LISTADO DE SECUENCIAS <110> YANG, Zhi-yong NABEL, Gary J. WU, Lan SEUNG, Edward WEI, Ronnie BENINGA, Jochen RAO, Ercole LEUSCHNER, Wulf Dirk BEIL, Christian LANGE, Christian CORVEY, Carsten <120> PROTEÍNAS DE UNIÓN TRIESPECÍFICAS Y/O TRIVALENTES <130> 183952027140 <140> Sin asignar <141> Simultáneamente con la presente <150> US 62/322,036 <151> 2016-04-13 <150> US 62/331,191 <151> 2016-05-03 <150> US 62/412,187 <151> 2016-10-24 <150> EP 17305298.6 <151> 2017-03-17 <160> 179 <170> FastSEQ para Windows Version 4.0 <210> 1 <211> 447 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 1 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Asn Ile Lys Asp Thr 20 25 30 Tyr Ile His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Arg Ile Tyr Pro Thr Asn Gly Tyr Thr Arg Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Ala Asp Thr Ser Lys Asn Thr Ala Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ser Arg Trp Gly Gly Asp Gly Phe Tyr Ala Met Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser Ala Ser Thr Lys Gly Pro Ser Val 115 120 125 Phe Pro Leu Ala Pro Cys Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala 130 135 140 Leu Gly Cys Leu Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val Ser 145 150 155 160 Trp Asn Ser Gly Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val 165 170 175 Leu Gln Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro 180 185 190 Ser Ser Ser Leu Gly Thr Lys Thr Tyr Thr Cys Asn Val Asp His Lys 195 200 205 Pro Ser Asn Thr Lys Val Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro 210 215 220 Pro Cys Pro Pro Cys Pro Ala Pro Glu Phe Leu Gly Gly Pro Ser Val 225 230 235 240 Phe Leu Phe Pro Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr 245 250 255 Pro Glu Val Thr Cys Val Val Val Asp Val Ser Gln Glu Asp Pro Glu 260 265 270 Val Gln Phe Asn Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys 275 280 285 Thr Lys Pro Arg Glu Glu Gln Phe Asn Ser Thr Tyr Arg Val Val Ser 290 295 300 Val Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys 305 310 315 320 Cys Lys Val Ser Asn Lys Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile 325 330 335 Ser Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro 340 345 350 Pro Cys Gln Glu Glu Met Thr Lys Asn Gln Val Ser Leu Trp Cys Leu 355 360 365 Val Lys Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn 370 375 380 Gly Gln Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser 385 390 395 400 Asp Gly Ser Phe Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg 405 410 415 Trp Gln Glu Gly Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu 420 425 430 His Asn His Tyr Thr Gln Lys Ser Leu Ser Leu Ser Leu Gly Lys 435 440 445 <210> 2 <211> 214 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 2 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Asp Val Asn Thr Ala 20 25 30 Val Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Ser Ala Ser Phe Leu Tyr Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Arg Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln His Tyr Thr Thr Pro Pro 85 90 95 Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys Arg Thr Val Ala Ala 100 105 110 Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly 115 120 125 Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala 130 135 140 Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln 145 150 155 160 Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser 165 170 175 Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr 180 185 190 Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser 195 200 205 Phe Asn Arg Gly Glu Cys 210 <210> 3 <211> 571 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 3 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Thr Phe Thr Ser Tyr 20 25 30 Tyr Ile His Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Ser Ile Tyr Pro Gly Asn Val Asn Thr Asn Tyr Ala Gln Lys Phe 50 55 60 Gln Gly Arg Ala Thr Leu Thr Val Asp Thr Ser Ile Ser Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Arg Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Ser His Tyr Gly Leu Asp Trp Asn Phe Asp Val Trp Gly Lys 100 105 110 Gly Thr Thr Val Thr Val Ser Ser Ser Gln Val Gln Leu Val Glu Ser 115 120 125 Gly Gly Gly Val Val Gln Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala 130 135 140 Ala Ser Gly Phe Thr Phe Thr Lys Ala Trp Met His Trp Val Arg Gln 145 150 155 160 Ala Pro Gly Lys Gln Leu Glu Trp Val Ala Gln Ile Lys Asp Lys Ser 165 170 175 Asn Ser Tyr Ala Thr Tyr Tyr Ala Asp Ser Val Lys Gly Arg Phe Thr 180 185 190 Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 195 200 205 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Arg Gly Val Tyr Tyr 210 215 220 Ala Leu Ser Pro Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val 225 230 235 240 Ser Ser Arg Thr Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala 245 250 255 Pro Cys Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala Leu Gly Cys Leu 260 265 270 Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly 275 280 285 Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser 290 295 300 Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu 305 310 315 320 Gly Thr Lys Thr Tyr Thr Cys Asn Val Asp His Lys Pro Ser Asn Thr 325 330 335 Lys Val Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro Pro Cys Pro Pro 340 345 350 Cys Pro Ala Pro Glu Phe Leu Gly Gly Pro Ser Val Phe Leu Phe Pro 355 360 365 Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr 370 375 380 Cys Val Val Val Asp Val Ser Gln Glu Asp Pro Glu Val Gln Phe Asn 385 390 395 400 Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg 405 410 415 Glu Glu Gln Phe Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val 420 425 430 Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser 435 440 445 Asn Lys Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile Ser Lys Ala Lys 450 455 460 Gly Gln Pro Arg Glu Pro Gln Val Cys Thr Leu Pro Pro Ser Gln Glu 465 470 475 480 Glu Met Thr Lys Asn Gln Val Ser Leu Ser Cys Ala Val Lys Gly Phe 485 490 495 Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu 500 505 510 Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe 515 520 525 Phe Leu Val Ser Lys Leu Thr Val Asp Lys Ser Arg Trp Gln Glu Gly 530 535 540 Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn His Tyr 545 550 555 560 Thr Gln Lys Ser Leu Ser Leu Ser Leu Gly Lys 565 570 <210> 4 <211> 338 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 4 Asp Ile Val Met Thr Gln Thr Pro Leu Ser Leu Ser Val Thr Pro Gly 1 5 10 15 Gln Pro Ala Ser Ile Ser Cys Lys Ser Ser Gln Ser Leu Val His Asn 20 25 30 Asn Ala Asn Thr Tyr Leu Ser Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Gln Ser Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Gly Gln Gly 85 90 95 Thr Gln Tyr Pro Phe Thr Phe Gly Ser Gly Thr Lys Val Glu Ile Lys 100 105 110 Gly Gln Pro Lys Ala Ala Pro Asp Ile Gln Met Thr Gln Ser Pro Ser 115 120 125 Ser Leu Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr Cys Gln Ala 130 135 140 Ser Gln Asn Ile Tyr Val Trp Leu Asn Trp Tyr Gln Gln Lys Pro Gly 145 150 155 160 Lys Ala Pro Lys Leu Leu Ile Tyr Lys Ala Ser Asn Leu His Thr Gly 165 170 175 Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu 180 185 190 Thr Ile Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr Tyr Tyr Cys Gln 195 200 205 Gln Gly Gln Thr Tyr Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu 210 215 220 Ile Lys Thr Lys Gly Pro Ser Arg Thr Val Ala Ala Pro Ser Val Phe 225 230 235 240 Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly Thr Ala Ser Val 245 250 255 Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala Lys Val Gln Trp 260 265 270 Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln Glu Ser Val Thr 275 280 285 Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser Ser Thr Leu Thr 290 295 300 Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr Ala Cys Glu Val 305 310 315 320 Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser Phe Asn Arg Gly 325 330 335 Glu Cys <210> 5 <211> 1341 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 5 gaagtgcagc tggtggaatc tggcggcgga ctggtgcagc ctggcggatc tctgagactg 60 agctgtgccg ccagcggctt caacatcaag gacacctaca tccactgggt gcgccaggcc 120 cctggcaagg gactggaatg ggtggccaga atctacccca ccaacggcta caccagatac 180 gccgacagcg tgaagggccg gttcaccatc agcgccgaca ccagcaagaa caccgcctac 240 ctgcagatga acagcctgcg ggccgaggac accgccgtgt actactgtag tagatgggga 300 ggcgacggct tctacgccat ggactattgg ggccagggca ccctcgtgac cgtgtctagt 360 gcgtcgacca agggcccatc ggtgttccct ctggcccctt gcagcagaag caccagcgaa 420 tctacagccg ccctgggctg cctcgtgaag gactactttc ccgagcccgt gaccgtgtcc 480 tggaactctg gcgctctgac aagcggcgtg cacacctttc cagccgtgct ccagagcagc 540 ggcctgtact ctctgagcag cgtcgtgaca gtgcccagca gcagcctggg caccaagacc 600 tacacctgta acgtggacca caagcccagc aacaccaagg tggacaagcg ggtggaatct 660 aagtacggcc ctccctgccc tccttgccca gcccctgaat ttctgggcgg accctccgtg 720 ttcctgttcc ccccaaagcc caaggacacc ctgatgatca gccggacccc cgaagtgacc 780 tgcgtggtgg tggatgtgtc ccaggaagat cccgaggtgc agttcaattg gtacgtggac 840 ggcgtggaag tgcacaacgc caagaccaag cccagagagg aacagttcaa cagcacctac 900 cgggtggtgt ccgtgctgac cgtgctgcac caggactggc tgaacggcaa agagtacaag 960 tgcaaggtgt ccaacaaggg cctgcccagc tccatcgaga aaaccatcag caaggccaag 1020 ggccagcccc gcgagcctca agtgtatacc ctgccccctt gccaggaaga gatgaccaag 1080 aaccaggtgt ccctgtggtg tctcgtgaaa ggcttctacc ccagcgacat tgccgtggaa 1140 tgggagagca acggccagcc cgagaacaac tacaagacca ccccccctgt gctggacagc 1200 gacggctcat tcttcctgta ctccaagctg accgtggaca agagccggtg gcaggaaggc 1260 aacgtgttca gctgctccgt gatgcacgag gccctgcaca accactacac ccagaagtcc 1320 ctgtctctgt ccctgggcaa g 1341 <210> 6 <211> 642 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 6 gacatccaga tgacccagag ccccagcagc ctgtctgcca gcgtgggcga cagagtgacc 60 atcacctgta gagccagcca ggacgtgaac accgccgtgg cctggtatca gcagaagcct 120 ggcaaggccc ccaagctgct gatctacagc gccagcttcc tgtacagcgg cgtgcccagc 180 agattcagcg gaagcagaag cggcaccgac ttcaccctga ccatcagctc cctgcagccc 240 gaggacttcg ccacctacta ctgccagcag cactacacca ccccccccac atttggccag 300 ggcaccaagg tggaaatcaa gcgtacggtg gccgctccca gcgtgttcat cttcccacct 360 agcgacgagc agctgaagtc cggcacagcc tctgtcgtgt gcctgctgaa caacttctac 420 ccccgcgagg ccaaagtgca gtggaaggtg gacaacgccc tgcagagcgg caacagccag 480 gaaagcgtga ccgagcagga cagcaaggac tccacctaca gcctgagcag caccctgaca 540 ctgagcaagg ccgactacga gaagcacaag gtgtacgcct gcgaagtgac ccaccagggc 600 ctgtctagcc ccgtgaccaa gagcttcaac cggggcgagt gt 642 <210> 7 <211> 1713 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 7 caggtgcagc tggtgcagtc tggcgccgag gtcgtgaaac ctggcgcctc tgtgaaggtg 60 tcctgcaagg ccagcggcta cacctttacc agctactaca tccactgggt gcgccaggcc 120 cctggacagg gactggaatg gatcggcagc atctaccccg gcaacgtgaa caccaactac 180 gcccagaagt tccagggcag agccaccctg accgtggaca ccagcatcag caccgcctac 240 atggaactga gccggctgag aagcgacgac accgccgtgt actactgcac ccggtcccac 300 tacggcctgg attggaactt cgacgtgtgg ggcaagggca ccaccgtgac agtgtctagc 360 agccaggtgc agctggtgga atctggcggc ggagtggtgc agcctggcag aagcctgaga 420 ctgagctgtg ccgccagcgg cttcaccttc accaaggcct ggatgcactg ggtgcgccag 480 gcccctggaa agcagctgga atgggtggcc cagatcaagg acaagagcaa cagctacgcc 540 acctactacg ccgacagcgt gaagggccgg ttcaccatca gccgggacga cagcaagaac 600 accctgtacc tgcagatgaa cagcctgcgg gccgaggaca ccgccgtgta ctactgtcgg 660 ggcgtgtact atgccctgag ccccttcgat tactggggcc agggaaccct cgtgaccgtg 720 tctagtcgga ccgccagcac aaagggccca tcggtgttcc ctctggcccc ttgcagcaga 780 agcaccagcg aatctacagc cgccctgggc tgcctcgtga aggactactt tcccgagccc 840 gtgaccgtgt cctggaactc tggcgctctg acaagcggcg tgcacacctt tccagccgtg 900 ctccagagca gcggcctgta ctctctgagc agcgtcgtga cagtgcccag cagcagcctg 960 ggcaccaaga cctacacctg taacgtggac cacaagccca gcaacaccaa ggtggacaag 1020 cgggtggaat ctaagtacgg ccctccctgc cctccttgcc cagcccctga atttctgggc 1080 ggaccctccg tgttcctgtt ccccccaaag cccaaggaca ccctgatgat cagccggacc 1140 cccgaagtga cctgcgtggt ggtggatgtg tcccaggaag atcccgaggt gcagttcaat 1200 tggtacgtgg acggcgtgga agtgcacaac gccaagacca agcccagaga ggaacagttc 1260 aacagcacct accgggtggt gtccgtgctg accgtgctgc accaggactg gctgaacggc 1320 aaagagtaca agtgcaaggt gtccaacaag ggcctgccca gctccatcga gaaaaccatc 1380 agcaaggcca agggccagcc ccgcgagcct caagtgtgta ccctgccccc tagccaggaa 1440 gagatgacca agaaccaggt gtccctgagc tgtgccgtga aaggcttcta ccccagcgac 1500 attgccgtgg aatgggagag caacggccag cccgagaaca actacaagac caccccccct 1560 gtgctggaca gcgacggctc attcttcctg gtgtccaagc tgaccgtgga caagagccgg 1620 tggcaggaag gcaacgtgtt cagctgctcc gtgatgcacg aggccctgca caaccactac 1680 acccagaagt ccctgtctct gtccctgggc aag 1713 <210> 8 <211> 1014 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 8 gacatcgtga tgacccagac ccccctgagc ctgagcgtga cacctggaca gcctgccagc 60 atcagctgca agagcagcca gagcctggtg cacaacaacg ccaacaccta cctgagctgg 120 tatctgcaga agcccggcca gagcccccag tccctgatct acaaggtgtc caacagattc 180 agcggcgtgc ccgacagatt ctccggcagc ggctctggca ccgacttcac cctgaagatc 240 agccgggtgg aagccgagga cgtgggcgtg tactattgtg gccagggcac ccagtacccc 300 ttcacctttg gcagcggcac caaggtggaa atcaagggcc agcccaaggc cgcccccgac 360 atccagatga cccagagccc cagcagcctg tctgccagcg tgggcgacag agtgaccatc 420 acctgtcagg ccagccagaa catctacgtg tggctgaact ggtatcagca gaagcccggc 480 aaggccccca agctgctgat ctacaaggcc agcaacctgc acaccggcgt gcccagcaga 540 ttttctggca gcggctccgg caccgacttc accctgacaa tcagctccct gcagcccgag 600 gacattgcca cctactactg ccagcagggc cagacctacc cctacacctt tggccagggc 660 accaagctgg aaatcaagac caagggcccc agccgtacgg tggccgctcc cagcgtgttc 720 atcttcccac ctagcgacga gcagctgaag tccggcacag cctctgtcgt gtgcctgctg 780 aacaacttct acccccgcga ggccaaagtg cagtggaagg tggacaacgc cctgcagagc 840 ggcaacagcc aggaaagcgt gaccgagcag gacagcaagg actccaccta cagcctgagc 900 agcaccctga cactgagcaa ggccgactac gagaagcaca aggtgtacgc ctgcgaagtg 960 acccaccagg gcctgtctag ccccgtgacc aagagcttca accggggcga gtgt 1014 <210> 9 <211> 571 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 9 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Gln 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Phe Ser Leu Ser Asp Tyr 20 25 30 Gly Val His Trp Val Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Ala Gly Gly Gly Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Lys Thr Ile Ser Lys Asp Thr Ser Lys Asn Gln Val Ser Leu 65 70 75 80 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 85 90 95 Arg Asp Lys Gly Tyr Ser Tyr Tyr Tyr Ser Met Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Thr Val Thr Val Ser Ser Ser Gln Val Gln Leu Val Glu Ser 115 120 125 Gly Gly Gly Val Val Gln Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala 130 135 140 Ala Ser Gly Phe Thr Phe Thr Lys Ala Trp Met His Trp Val Arg Gln 145 150 155 160 Ala Pro Gly Lys Gln Leu Glu Trp Val Ala Gln Ile Lys Asp Lys Ser 165 170 175 Asn Ser Tyr Ala Thr Tyr Tyr Ala Asp Ser Val Lys Gly Arg Phe Thr 180 185 190 Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 195 200 205 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Arg Gly Val Tyr Tyr 210 215 220 Ala Leu Ser Pro Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val 225 230 235 240 Ser Ser Arg Thr Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala 245 250 255 Pro Cys Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala Leu Gly Cys Leu 260 265 270 Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly 275 280 285 Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser 290 295 300 Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu 305 310 315 320 Gly Thr Lys Thr Tyr Thr Cys Asn Val Asp His Lys Pro Ser Asn Thr 325 330 335 Lys Val Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro Pro Cys Pro Pro 340 345 350 Cys Pro Ala Pro Glu Phe Leu Gly Gly Pro Ser Val Phe Leu Phe Pro 355 360 365 Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr 370 375 380 Cys Val Val Val Asp Val Ser Gln Glu Asp Pro Glu Val Gln Phe Asn 385 390 395 400 Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg 405 410 415 Glu Glu Gln Phe Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val 420 425 430 Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser 435 440 445 Asn Lys Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile Ser Lys Ala Lys 450 455 460 Gly Gln Pro Arg Glu Pro Gln Val Cys Thr Leu Pro Pro Ser Gln Glu 465 470 475 480 Glu Met Thr Lys Asn Gln Val Ser Leu Ser Cys Ala Val Lys Gly Phe 485 490 495 Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu 500 505 510 Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe 515 520 525 Phe Leu Val Ser Lys Leu Thr Val Asp Lys Ser Arg Trp Gln Glu Gly 530 535 540 Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn His Tyr 545 550 555 560 Thr Gln Lys Ser Leu Ser Leu Ser Leu Gly Lys 565 570 <210> 10 <211> 342 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 10 Asp Ile Val Met Thr Gln Thr Pro Leu Ser Leu Ser Val Thr Pro Gly 1 5 10 15 Gln Pro Ala Ser Ile Ser Cys Lys Ser Ser Gln Ser Leu Val His Asn 20 25 30 Asn Ala Asn Thr Tyr Leu Ser Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Gln Ser Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Gly Gln Gly 85 90 95 Thr Gln Tyr Pro Phe Thr Phe Gly Ser Gly Thr Lys Val Glu Ile Lys 100 105 110 Gly Gln Pro Lys Ala Ala Pro Asp Ile Val Leu Thr Gln Ser Pro Ala 115 120 125 Ser Leu Ala Val Ser Pro Gly Gln Arg Ala Thr Ile Thr Cys Arg Ala 130 135 140 Ser Glu Ser Val Glu Tyr Tyr Val Thr Ser Leu Met Gln Trp Tyr Gln 145 150 155 160 Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile Phe Ala Ala Ser Asn 165 170 175 Val Glu Ser Gly Val Pro Ala Arg Phe Ser Gly Ser Gly Ser Gly Thr 180 185 190 Asp Phe Thr Leu Thr Ile Asn Pro Val Glu Ala Asn Asp Val Ala Asn 195 200 205 Tyr Tyr Cys Gln Gln Ser Arg Lys Val Pro Tyr Thr Phe Gly Gln Gly 210 215 220 Thr Lys Leu Glu Ile Lys Thr Lys Gly Pro Ser Arg Thr Val Ala Ala 225 230 235 240 Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly 245 250 255 Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala 260 265 270 Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln 275 280 285 Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser 290 295 300 Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr 305 310 315 320 Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser 325 330 335 Phe Asn Arg Gly Glu Cys 340 <210> 11 <211> 1713 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 11 caggtgcagc tgcaggaatc tggccctggc ctcgtgaagc ctagccagac cctgagcctg 60 acctgtaccg tgtccggctt cagcctgagc gactacggcg tgcactgggt gcgccagcca 120 cctggaaaag gcctggaatg gctgggcgtg atctgggctg gcggaggcac caactacaac 180 cccagcctga agtccagaaa gaccatcagc aaggacacca gcaagaacca ggtgtccctg 240 aagctgagca gcgtgacagc cgccgatacc gccgtgtact actgcgccag agacaagggc 300 tacagctact actacagcat ggactactgg ggccagggca ccaccgtgac cgtgtcatcc 360 tctcaggtgc agctggtgga atctggcggc ggagtggtgc agcctggcag aagcctgaga 420 ctgagctgtg ccgccagcgg cttcaccttc accaaggcct ggatgcactg ggtgcgccag 480 gcccctggaa agcagctgga atgggtggcc cagatcaagg acaagagcaa cagctacgcc 540 acctactacg ccgacagcgt gaagggccgg ttcaccatca gccgggacga cagcaagaac 600 accctgtacc tgcagatgaa cagcctgcgg gccgaggaca ccgccgtgta ctactgtcgg 660 ggcgtgtact atgccctgag ccccttcgat tactggggcc agggaaccct cgtgaccgtg 720 tctagtcgga ccgcttcgac caagggccca tcggtgttcc ctctggcccc ttgcagcaga 780 agcaccagcg aatctacagc cgccctgggc tgcctcgtga aggactactt tcccgagccc 840 gtgaccgtgt cctggaactc tggcgctctg acaagcggcg tgcacacctt tccagccgtg 900 ctccagagca gcggcctgta ctctctgagc agcgtcgtga cagtgcccag cagcagcctg 960 ggcaccaaga cctacacctg taacgtggac cacaagccca gcaacaccaa ggtggacaag 1020 cgggtggaat ctaagtacgg ccctccctgc cctccttgcc cagcccctga atttctgggc 1080 ggaccctccg tgttcctgtt ccccccaaag cccaaggaca ccctgatgat cagccggacc 1140 cccgaagtga cctgcgtggt ggtggatgtg tcccaggaag atcccgaggt gcagttcaat 1200 tggtacgtgg acggcgtgga agtgcacaac gccaagacca agcccagaga ggaacagttc 1260 aacagcacct accgggtggt gtccgtgctg accgtgctgc accaggactg gctgaacggc 1320 aaagagtaca agtgcaaggt gtccaacaag ggcctgccca gctccatcga gaaaaccatc 1380 agcaaggcca agggccagcc ccgcgagcct caagtgtgta ccctgccccc tagccaggaa 1440 gagatgacca agaaccaggt gtccctgagc tgtgccgtga aaggcttcta ccccagcgac 1500 attgccgtgg aatgggagag caacggccag cccgagaaca actacaagac caccccccct 1560 gtgctggaca gcgacggctc attcttcctg gtgtccaagc tgaccgtgga caagagccgg 1620 tggcaggaag gcaacgtgtt cagctgctcc gtgatgcacg aggccctgca caaccactac 1680 acccagaagt ccctgtctct gtccctgggc aag 1713 <210> 12 <211> 1026 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 12 gacatcgtga tgacccagac ccccctgagc ctgagcgtga cacctggaca gcctgccagc 60 atcagctgca agagcagcca gagcctggtg cacaacaacg ccaacaccta cctgagctgg 120 tatctgcaga agcccggcca gagcccccag tccctgatct acaaggtgtc caacagattc 180 agcggcgtgc ccgacagatt ctccggcagc ggctctggca ccgacttcac cctgaagatc 240 agccgggtgg aagccgagga cgtgggcgtg tactattgtg gccagggcac ccagtacccc 300 ttcacctttg gcagcggcac caaggtggaa atcaagggcc agcccaaggc cgcccccgac 360 atcgtgctga cacagagccc tgctagcctg gccgtgtctc ctggacagag ggccaccatc 420 acctgtagag ccagcgagag cgtggaatat tacgtgacca gcctgatgca gtggtatcag 480 cagaagcccg gccagccccc caagctgctg attttcgccg ccagcaacgt ggaaagcggc 540 gtgccagcca gattttccgg cagcggctct ggcaccgact tcaccctgac catcaacccc 600 gtggaagcca acgacgtggc caactactac tgccagcaga gccggaaggt gccctacacc 660 tttggccagg gcaccaagct ggaaatcaag accaagggcc ccagccgtac ggtggccgct 720 cccagcgtgt tcatcttccc acctagcgac gagcagctga agtccggcac agcctctgtc 780 gtgtgcctgc tgaacaactt ctacccccgc gaggccaaag tgcagtggaa ggtggacaac 840 gccctgcaga gcggcaacag ccaggaaagc gtgaccgagc aggacagcaa ggactccacc 900 tacagcctga gcagcaccct gacactgagc aaggccgact acgagaagca caaggtgtac 960 gcctgcgaag tgacccacca gggcctgtct agccccgtga ccaagagctt caaccggggc 1020 gagtgt 1026 <210> 13 <211> 451 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 13 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Ala Phe Ser Ser Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Gln Ile Trp Pro Gly Asp Gly Asp Thr Asn Tyr Asn Gln Lys Phe 50 55 60 Lys Gly Arg Ala Thr Leu Thr Ala Asp Glu Ser Thr Ser Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Arg Glu Thr Thr Thr Val Gly Arg Tyr Tyr Tyr Ala Met Asp 100 105 110 Tyr Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser Ala Ser Thr Lys 115 120 125 Gly Pro Ser Val Phe Pro Leu Ala Pro Cys Ser Arg Ser Thr Ser Glu 130 135 140 Ser Thr Ala Ala Leu Gly Cys Leu Val Lys Asp Tyr Phe Pro Glu Pro 145 150 155 160 Val Thr Val Ser Trp Asn Ser Gly Ala Leu Thr Ser Gly Val His Thr 165 170 175 Phe Pro Ala Val Leu Gln Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val 180 185 190 Val Thr Val Pro Ser Ser Ser Leu Gly Thr Lys Thr Tyr Thr Cys Asn 195 200 205 Val Asp His Lys Pro Ser Asn Thr Lys Val Asp Lys Arg Val Glu Ser 210 215 220 Lys Tyr Gly Pro Pro Cys Pro Pro Cys Pro Ala Pro Glu Phe Leu Gly 225 230 235 240 Gly Pro Ser Val Phe Leu Phe Pro Pro Lys Pro Lys Asp Thr Leu Met 245 250 255 Ile Ser Arg Thr Pro Glu Val Thr Cys Val Val Val Asp Val Ser Gln 260 265 270 Glu Asp Pro Glu Val Gln Phe Asn Trp Tyr Val Asp Gly Val Glu Val 275 280 285 His Asn Ala Lys Thr Lys Pro Arg Glu Glu Gln Phe Asn Ser Thr Tyr 290 295 300 Arg Val Val Ser Val Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly 305 310 315 320 Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys Gly Leu Pro Ser Ser Ile 325 330 335 Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln Val 340 345 350 Tyr Thr Leu Pro Pro Cys Gln Glu Glu Met Thr Lys Asn Gln Val Ser 355 360 365 Leu Trp Cys Leu Val Lys Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu 370 375 380 Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro 385 390 395 400 Val Leu Asp Ser Asp Gly Ser Phe Phe Leu Tyr Ser Lys Leu Thr Val 405 410 415 Asp Lys Ser Arg Trp Gln Glu Gly Asn Val Phe Ser Cys Ser Val Met 420 425 430 His Glu Ala Leu His Asn His Tyr Thr Gln Lys Ser Leu Ser Leu Ser 435 440 445 Leu Gly Lys 450 <210> 14 <211> 218 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 14 Asp Leu Val Leu Thr Gln Ser Pro Ala Ser Leu Ala Val Ser Pro Gly 1 5 10 15 Gln Arg Ala Thr Ile Thr Cys Lys Ala Ser Gln Ser Val Asp Tyr Asp 20 25 30 Gly Asp Ser Tyr Leu Asn Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Tyr Asp Ala Ser Asn Leu Val Ser Gly Val Pro Ala 50 55 60 Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Asn 65 70 75 80 Pro Val Glu Ala Asn Asp Thr Ala Asn Tyr Tyr Cys Gln Gln Ser Thr 85 90 95 Glu Asp Pro Trp Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys Arg 100 105 110 Thr Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln 115 120 125 Leu Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr 130 135 140 Pro Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser 145 150 155 160 Gly Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr 165 170 175 Tyr Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys 180 185 190 His Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro 195 200 205 Val Thr Lys Ser Phe Asn Arg Gly Glu Cys 210 215 <210> 15 <211> 1353 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 15 caggtgcagc tggtgcagag cggcgccgaa gtgaagaagc ctggcagcag cgtgaaggtg 60 agctgcaagg ccagcggcta tgccttcagc agctactgga tgaactgggt gaggcaggca 120 cctggccagg gcctggagtg gataggccaa atatggcctg gcgatggcga caccaactac 180 aaccagaagt tcaagggcag agcgaccttg accgccgacg agagcaccag caccgcgtac 240 atggagctga gcagcctgag gagcgaggac accgccgtgt actattgcgc cagaagggag 300 accaccaccg tgggcaggta ctactacgcc atggactact ggggccaggg aaccaccgtg 360 accgtgagca gcgcctcgac caagggccca tcggtgttcc ctctggcccc ttgcagcaga 420 agcaccagcg aatctacagc cgccctgggc tgcctcgtga aggactactt tcccgagccc 480 gtgaccgtgt cctggaactc tggcgctctg acaagcggcg tgcacacctt tccagccgtg 540 ctccagagca gcggcctgta ctctctgagc agcgtcgtga cagtgcccag cagcagcctg 600 ggcaccaaga cctacacctg taacgtggac cacaagccca gcaacaccaa ggtggacaag 660 cgggtggaat ctaagtacgg ccctccctgc cctccttgcc cagcccctga atttctgggc 720 ggaccctccg tgttcctgtt ccccccaaag cccaaggaca ccctgatgat cagccggacc 780 cccgaagtga cctgcgtggt ggtggatgtg tcccaggaag atcccgaggt gcagttcaat 840 tggtacgtgg acggcgtgga agtgcacaac gccaagacca agcccagaga ggaacagttc 900 aacagcacct accgggtggt gtccgtgctg accgtgctgc accaggactg gctgaacggc 960 aaagagtaca agtgcaaggt gtccaacaag ggcctgccca gctccatcga gaaaaccatc 1020 agcaaggcca agggccagcc ccgcgagcct caagtgtata ccctgccccc ttgccaggaa 1080 gagatgacca agaaccaggt gtccctgtgg tgtctcgtga aaggcttcta ccccagcgac 1140 attgccgtgg aatgggagag caacggccag cccgagaaca actacaagac caccccccct 1200 gtgctggaca gcgacggctc attcttcctg tactccaagc tgaccgtgga caagagccgg 1260 tggcaggaag gcaacgtgtt cagctgctcc gtgatgcacg aggccctgca caaccactac 1320 acccagaagt ccctgtctct gtccctgggc aag 1353 <210> 16 <211> 654 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 16 gacctcgtgc tgacccagag ccctgcgagc ctggctgtga gccctggcca gagagccacc 60 atcacctgca aagccagcca gagcgtggac tacgacggcg acagctacct caactggtac 120 cagcagaagc ctggccagcc ccccaagctg ctgatttacg atgccagcaa cctggtgagc 180 ggcgtgcctg ctagattcag cggctccggc agcggcaccg acttcaccct gaccatcaac 240 cccgtggagg ccaacgacac cgccaactac tactgccagc agagcacgga ggacccctgg 300 accttcggcc agggcacaaa gctggagatc aagcgtacgg tggccgctcc cagcgtgttc 360 atcttcccac ctagcgacga gcagctgaag tccggcacag cctctgtcgt gtgcctgctg 420 aacaacttct acccccgcga ggccaaagtg cagtggaagg tggacaacgc cctgcagagc 480 ggcaacagcc aggaaagcgt gaccgagcag gacagcaagg actccaccta cagcctgagc 540 agcaccctga cactgagcaa ggccgactac gagaagcaca aggtgtacgc ctgcgaagtg 600 acccaccagg gcctgtctag ccccgtgacc aagagcttca accggggcga gtgt 654 <210> 17 <211> 447 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 17 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Ala Lys Pro Gly Thr 1 5 10 15 Ser Val Lys Leu Ser Cys Lys Ala Ser Gly Tyr Thr Phe Thr Asp Tyr 20 25 30 Trp Met Gln Trp Val Lys Gln Arg Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Thr Ile Tyr Pro Gly Asp Gly Asp Thr Gly Tyr Ala Gln Lys Phe 50 55 60 Gln Gly Lys Ala Thr Leu Thr Ala Asp Lys Ser Ser Lys Thr Val Tyr 65 70 75 80 Met His Leu Ser Ser Leu Ala Ser Glu Asp Ser Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gly Asp Tyr Tyr Gly Ser Asn Ser Leu Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Ser Val Thr Val Ser Ser Ala Ser Thr Lys Gly Pro Ser Val 115 120 125 Phe Pro Leu Ala Pro Cys Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala 130 135 140 Leu Gly Cys Leu Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val Ser 145 150 155 160 Trp Asn Ser Gly Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val 165 170 175 Leu Gln Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro 180 185 190 Ser Ser Ser Leu Gly Thr Lys Thr Tyr Thr Cys Asn Val Asp His Lys 195 200 205 Pro Ser Asn Thr Lys Val Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro 210 215 220 Pro Cys Pro Pro Cys Pro Ala Pro Glu Phe Leu Gly Gly Pro Ser Val 225 230 235 240 Phe Leu Phe Pro Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr 245 250 255 Pro Glu Val Thr Cys Val Val Val Asp Val Ser Gln Glu Asp Pro Glu 260 265 270 Val Gln Phe Asn Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys 275 280 285 Thr Lys Pro Arg Glu Glu Gln Phe Asn Ser Thr Tyr Arg Val Val Ser 290 295 300 Val Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys 305 310 315 320 Cys Lys Val Ser Asn Lys Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile 325 330 335 Ser Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro 340 345 350 Pro Cys Gln Glu Glu Met Thr Lys Asn Gln Val Ser Leu Trp Cys Leu 355 360 365 Val Lys Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn 370 375 380 Gly Gln Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser 385 390 395 400 Asp Gly Ser Phe Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg 405 410 415 Trp Gln Glu Gly Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu 420 425 430 His Asn His Tyr Thr Gln Lys Ser Leu Ser Leu Ser Leu Gly Lys 435 440 445 <210> 18 <211> 214 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 18 Asp Ile Val Met Thr Gln Ser His Leu Ser Met Ser Thr Ser Leu Gly 1 5 10 15 Asp Pro Val Ser Ile Thr Cys Lys Ala Ser Gln Asp Val Ser Thr Val 20 25 30 Val Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ser Pro Arg Arg Leu Ile 35 40 45 Tyr Ser Ala Ser Tyr Arg Tyr Ile Gly Val Pro Asp Arg Phe Thr Gly 50 55 60 Ser Gly Ala Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Val Gln Ala 65 70 75 80 Glu Asp Leu Ala Val Tyr Tyr Cys Gln Gln His Tyr Ser Pro Pro Tyr 85 90 95 Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Arg Thr Val Ala Ala 100 105 110 Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly 115 120 125 Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala 130 135 140 Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln 145 150 155 160 Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser 165 170 175 Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr 180 185 190 Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser 195 200 205 Phe Asn Arg Gly Glu Cys 210 <210> 19 <211> 1341 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 19 caggtgcagc tggtgcagtc tggcgccgaa gtggccaagc ctggcacaag cgtgaagctg 60 agctgcaagg ccagcggcta caccttcacc gactactgga tgcagtgggt caagcagagg 120 ccaggccagg gcctggaatg gatcggcaca atctatcccg gcgacggcga taccggctac 180 gcccagaagt ttcagggcaa ggccaccctg accgccgaca agagcagcaa gaccgtgtac 240 atgcacctga gcagcctggc cagcgaggac agcgccgtgt actattgcgc cagaggcgac 300 tactacggca gcaacagcct ggactattgg ggccagggca ccagcgtgac agtgtctagt 360 gcgtcgacca agggcccatc ggtgttccct ctggcccctt gcagcagaag caccagcgaa 420 tctacagccg ccctgggctg cctcgtgaag gactactttc ccgagcccgt gaccgtgtcc 480 tggaactctg gcgctctgac aagcggcgtg cacacctttc cagccgtgct ccagagcagc 540 ggcctgtact ctctgagcag cgtcgtgaca gtgcccagca gcagcctggg caccaagacc 600 tacacctgta acgtggacca caagcccagc aacaccaagg tggacaagcg ggtggaatct 660 aagtacggcc ctccctgccc tccttgccca gcccctgaat ttctgggcgg accctccgtg 720 ttcctgttcc ccccaaagcc caaggacacc ctgatgatca gccggacccc cgaagtgacc 780 tgcgtggtgg tggatgtgtc ccaggaagat cccgaggtgc agttcaattg gtacgtggac 840 ggcgtggaag tgcacaacgc caagaccaag cccagagagg aacagttcaa cagcacctac 900 cgggtggtgt ccgtgctgac cgtgctgcac caggactggc tgaacggcaa agagtacaag 960 tgcaaggtgt ccaacaaggg cctgcccagc tccatcgaga aaaccatcag caaggccaag 1020 ggccagcccc gcgagcctca agtgtatacc ctgccccctt gccaggaaga gatgaccaag 1080 aaccaggtgt ccctgtggtg tctcgtgaaa ggcttctacc ccagcgacat tgccgtggaa 1140 tgggagagca acggccagcc cgagaacaac tacaagacca ccccccctgt gctggacagc 1200 gacggctcat tcttcctgta ctccaagctg accgtggaca agagccggtg gcaggaaggc 1260 aacgtgttca gctgctccgt gatgcacgag gccctgcaca accactacac ccagaagtcc 1320 ctgtctctgt ccctgggcaa g 1341 <210> 20 <211> 642 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 20 gacatcgtga tgacccagag ccacctgagc atgagcacca gcctgggcga ccccgtgtcc 60 atcacctgta aagccagcca ggacgtgtcc accgtggtgg cctggtatca gcagaagcct 120 ggccagagcc ccagacggct gatctacagc gccagctatc ggtacatcgg cgtgcccgac 180 agattcaccg gaagcggagc cggcaccgac ttcaccttca ccatcagctc tgtgcaggcc 240 gaggacctgg ccgtgtacta ctgccagcag cactacagcc ccccctacac ctttggcgga 300 ggcaccaagc tggaaatcaa gcgtacggtg gccgctccca gcgtgttcat cttcccacct 360 agcgacgagc agctgaagtc cggcacagcc tctgtcgtgt gcctgctgaa caacttctac 420 ccccgcgagg ccaaagtgca gtggaaggtg gacaacgccc tgcagagcgg caacagccag 480 gaaagcgtga ccgagcagga cagcaaggac tccacctaca gcctgagcag caccctgaca 540 ctgagcaagg ccgactacga gaagcacaag gtgtacgcct gcgaagtgac ccaccagggc 600 ctgtctagcc ccgtgaccaa gagcttcaac cggggcgagt gt 642 <210> 21 <211> 445 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 21 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Ile Phe Thr Asn Tyr 20 25 30 Asn Ile His Trp Val Lys Lys Ser Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Ala Ile Tyr Pro Gly Asn Gly Asp Ala Pro Tyr Ser Gln Lys Phe 50 55 60 Gln Gly Lys Ala Thr Leu Thr Ala Asp Thr Ser Thr Ser Thr Thr Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Val Arg Ala Asn Trp Asp Val Ala Phe Ala Tyr Trp Gly Gln Gly Thr 100 105 110 Leu Val Thr Val Ser Ser Ala Ser Thr Lys Gly Pro Ser Val Phe Pro 115 120 125 Leu Ala Pro Cys Ser Arg Ser Thr Ser Glu Ser Thr Ala Ala Leu Gly 130 135 140 Cys Leu Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn 145 150 155 160 Ser Gly Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln 165 170 175 Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser 180 185 190 Ser Leu Gly Thr Lys Thr Tyr Thr Cys Asn Val Asp His Lys Pro Ser 195 200 205 Asn Thr Lys Val Asp Lys Arg Val Glu Ser Lys Tyr Gly Pro Pro Cys 210 215 220 Pro Pro Cys Pro Ala Pro Glu Phe Leu Gly Gly Pro Ser Val Phe Leu 225 230 235 240 Phe Pro Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu 245 250 255 Val Thr Cys Val Val Val Asp Val Ser Gln Glu Asp Pro Glu Val Gln 260 265 270 Phe Asn Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys 275 280 285 Pro Arg Glu Glu Gln Phe Asn Ser Thr Tyr Arg Val Val Ser Val Leu 290 295 300 Thr Val Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys 305 310 315 320 Val Ser Asn Lys Gly Leu Pro Ser Ser Ile Glu Lys Thr Ile Ser Lys 325 330 335 Ala Lys Gly Gln Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Cys 340 345 350 Gln Glu Glu Met Thr Lys Asn Gln Val Ser Leu Trp Cys Leu Val Lys 355 360 365 Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln 370 375 380 Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly 385 390 395 400 Ser Phe Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg Trp Gln 405 410 415 Glu Gly Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn 420 425 430 His Tyr Thr Gln Lys Ser Leu Ser Leu Ser Leu Gly Lys 435 440 445 <210> 22 <211> 213 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 22 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Lys Ala Ser Gln Asp Ile Asp Arg Tyr 20 25 30 Met Ala Trp Tyr Gln Asp Lys Pro Gly Lys Ala Pro Arg Leu Leu Ile 35 40 45 His Asp Thr Ser Thr Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Arg Asp Tyr Thr Leu Thr Ile Ser Asn Leu Glu Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Leu Gln Tyr Asp Asn Leu Trp Thr 85 90 95 Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Thr Val Ala Ala Pro 100 105 110 Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly Thr 115 120 125 Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala Lys 130 135 140 Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln Glu 145 150 155 160 Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser Ser 165 170 175 Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr Ala 180 185 190 Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser Phe 195 200 205 Asn Arg Gly Glu Cys 210 <210> 23 <211> 1335 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 23 caggtgcagc tggtgcagtc tggcgccgaa gtgaagaaac ccggcagcag cgtgaaggtg 60 tcctgcaagg ccagcggcta catcttcacc aactacaaca tccactgggt caagaagtcc 120 ccaggccagg gcctggaatg gatcggcgcc atctatcccg gaaacggcga cgccccttac 180 agccagaagt tccagggcaa ggccaccctg accgccgata ccagcacctc caccacctac 240 atggaactga gcagcctgcg gagcgaggac accgccgtgt actattgcgt gcgggccaac 300 tgggatgtgg ccttcgccta ttggggccag ggcacactcg tgaccgtgtc ctctgcgtcg 360 accaagggcc catcggtgtt ccctctggcc ccttgcagca gaagcaccag cgaatctaca 420 gccgccctgg gctgcctcgt gaaggactac tttcccgagc ccgtgaccgt gtcctggaac 480 tctggcgctc tgacaagcgg cgtgcacacc tttccagccg tgctccagag cagcggcctg 540 tactctctga gcagcgtcgt gacagtgccc agcagcagcc tgggcaccaa gacctacacc 600 tgtaacgtgg accacaagcc cagcaacacc aaggtggaca agcgggtgga atctaagtac 660 ggccctccct gccctccttg cccagcccct gaatttctgg gcggaccctc cgtgttcctg 720 ttccccccaa agcccaagga caccctgatg atcagccgga cccccgaagt gacctgcgtg 780 gtggtggatg tgtcccagga agatcccgag gtgcagttca attggtacgt ggacggcgtg 840 gaagtgcaca acgccaagac caagcccaga gaggaacagt tcaacagcac ctaccgggtg 900 gtgtccgtgc tgaccgtgct gcaccaggac tggctgaacg gcaaagagta caagtgcaag 960 gtgtccaaca agggcctgcc cagctccatc gagaaaacca tcagcaaggc caagggccag 1020 ccccgcgagc ctcaagtgta taccctgccc ccttgccagg aagagatgac caagaaccag 1080 gtgtccctgt ggtgtctcgt gaaaggcttc taccccagcg acattgccgt ggaatgggag 1140 agcaacggcc agcccgagaa caactacaag accacccccc ctgtgctgga cagcgacggc 1200 tcattcttcc tgtactccaa gctgaccgtg gacaagagcc ggtggcagga aggcaacgtg 1260 ttcagctgct ccgtgatgca cgaggccctg cacaaccact acacccagaa gtccctgtct 1320 ctgtccctgg gcaag 1335 <210> 24 <211> 639 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 24 gacatccaga tgacccagag ccccagcagc ctgtctgcca gcgtgggcga cagagtgacc 60 atcacatgca aggccagcca ggacatcgat cggtacatgg cctggtatca ggacaagccc 120 ggcaaggccc ccagactgct gatccacgat accagcacac tgcagagcgg cgtgcccagc 180 agattttccg gctctggcag cggcagagac tacaccctga ccatcagcaa cctggaaccc 240 gaggacttcg ccacctacta ctgcctgcag tacgacaacc tgtggacctt cggcggaggc 300 accaaggtgg aaatcaagcg tacggtggcc gctcccagcg tgttcatctt cccacctagc 360 gacgagcagc tgaagtccgg cacagcctct gtcgtgtgcc tgctgaacaa cttctacccc 420 cgcgaggcca aagtgcagtg gaaggtggac aacgccctgc agagcggcaa cagccaggaa 480 agcgtgaccg agcaggacag caaggactcc acctacagcc tgagcagcac cctgacactg 540 agcaaggccg actacgagaa gcacaaggtg tacgcctgcg aagtgaccca ccagggcctg 600 tctagccccg tgaccaagag cttcaaccgg ggcgagtgt 639 <210> 25 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 25 Gly Phe Asn Ile Lys Asp Thr Tyr 1 5 <210> 26 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 26 Ile Tyr Pro Thr Asn Gly Tyr Thr 1 5 <210> 27 <211> 13 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 27 Ser Arg Trp Gly Gly Asp Gly Phe Tyr Ala Met Asp Tyr 1 5 10 <210> 28 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 28 Gly Tyr Thr Phe Thr Ser Tyr Tyr 1 5 <210> 29 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 29 Ile Tyr Pro Gly Asn Val Asn Thr 1 5 <210> 30 <211> 13 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 30 Thr Arg Ser His Tyr Gly Leu Asp Trp Asn Phe Asp Val 1 5 10 <210> 31 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 31 Gly Phe Ser Leu Ser Asp Tyr Gly 1 5 <210> 32 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 32 Ile Trp Ala Gly Gly Gly Thr 1 5 <210> 33 <211> 13 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 33 Ala Arg Asp Lys Gly Tyr Ser Tyr Tyr Tyr Ser Met Asp 1 5 10 <210> 34 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 34 Gly Phe Thr Phe Thr Lys Ala Trp 1 5 <210> 35 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 35 Ile Lys Asp Lys Ser Asn Ser 1 5 <210> 36 <211> 12 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 36 Arg Gly Val Tyr Tyr Ala Leu Ser Pro Phe Asp Tyr 1 5 10 <210> 37 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 37 Gly Tyr Ala Phe Ser Ser Tyr Trp 1 5 <210> 38 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 38 Ile Trp Pro Gly Asp Gly Asp Thr 1 5 <210> 39 <211> 16 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 39 Ala Arg Arg Glu Thr Thr Thr Val Gly Arg Tyr Tyr Tyr Ala Met Asp 1 5 10 15 <210> 40 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 40 Gly Tyr Thr Phe Thr Asp Tyr Trp 1 5 <210> 41 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 41 Ile Tyr Pro Gly Asp Gly Asp Thr 1 5 <210> 42 <211> 13 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 42 Ala Arg Gly Asp Tyr Tyr Gly Ser Asn Ser Leu Asp Tyr 1 5 10 <210> 43 <211> 6 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 43 Gln Asp Val Asn Thr Ala 1 5 <210> 44 <211> 3 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 44 Ser Ala Ser 1 <210> 45 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 45 Gln Gln His Tyr Thr Thr Pro Pro Thr 1 5 <210> 46 <211> 6 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 46 Gln Asn Ile Tyr Val Trp 1 5 <210> 47 <211> 3 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 47 Lys Ala Ser 1 <210> 48 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 48 Gln Gln Gly Gln Thr Tyr Pro Tyr Thr 1 5 <210> 49 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 49 Glu Ser Val Glu Tyr Tyr Val Thr Ser Leu 1 5 10 <210> 50 <211> 3 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 50 Ala Ala Ser 1 <210> 51 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 51 Gln Gln Ser Arg Lys Val Pro Tyr Thr 1 5 <210> 52 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 52 Gln Ser Leu Val His Asn Asn Ala Asn Thr Tyr 1 5 10 <210> 53 <211> 3 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 53 Lys Val Ser 1 <210> 54 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 54 Gly Gln Gly Thr Gln Tyr Pro 1 5 <210> 55 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 55 Gln Ser Val Asp Tyr Asp Gly Asp Ser Tyr 1 5 10 <210> 56 <211> 3 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 56 Asp Ala Ser 1 <210> 57 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 57 Gln Gln Ser Thr Glu Asp Pro Trp Thr 1 5 <210> 58 <211> 6 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 58 Gln Asp Val Ser Thr Val 1 5 <210> 59 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 59 Gln Gln His Tyr Ser Pro Pro Tyr Thr 1 5 <210> 60 <211> 450 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 60 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Asp Asp Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Ala Ile Thr Trp Asn Ser Gly His Ile Asp Tyr Ala Asp Ser Val 50 55 60 Glu Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Val Ser Tyr Leu Ser Thr Ala Ser Ser Leu Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser Ala Ser Thr Lys Gly Pro Ser 115 120 125 Val Phe Pro Leu Ala Pro Ser Ser Lys Ser Thr Ser Gly Gly Thr Ala 130 135 140 Ala Leu Gly Cys Leu Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val 145 150 155 160 Ser Trp Asn Ser Gly Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala 165 170 175 Val Leu Gln Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val 180 185 190 Pro Ser Ser Ser Leu Gly Thr Gln Thr Tyr Ile Cys Asn Val Asn His 195 200 205 Lys Pro Ser Asn Thr Lys Val Asp Lys Lys Val Glu Pro Lys Ser Cys 210 215 220 Asp Lys Thr His Thr Cys Pro Pro Cys Pro Ala Pro Glu Leu Leu Gly 225 230 235 240 Gly Pro Ser Val Phe Leu Phe Pro Pro Lys Pro Lys Asp Thr Leu Met 245 250 255 Ile Ser Arg Thr Pro Glu Val Thr Cys Val Val Val Asp Val Ser His 260 265 270 Glu Asp Pro Glu Val Lys Phe Asn Trp Tyr Val Asp Gly Val Glu Val 275 280 285 His Asn Ala Lys Thr Lys Pro Arg Glu Glu Gln Tyr Asn Ser Thr Tyr 290 295 300 Arg Val Val Ser Val Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly 305 310 315 320 Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys Ala Leu Pro Ala Pro Ile 325 330 335 Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln Val 340 345 350 Cys Thr Leu Pro Pro Ser Arg Asp Glu Leu Thr Lys Asn Gln Val Ser 355 360 365 Leu Ser Cys Ala Val Lys Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu 370 375 380 Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro 385 390 395 400 Val Leu Asp Ser Asp Gly Ser Phe Phe Leu Val Ser Lys Leu Thr Val 405 410 415 Asp Lys Ser Arg Trp Gln Gln Gly Asn Val Phe Ser Cys Ser Val Met 420 425 430 His Glu Ala Leu His Asn His Tyr Thr Gln Lys Ser Leu Ser Leu Ser 435 440 445 Pro Gly 450 <210> 61 <211> 213 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 61 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Arg Asn Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Ala Ala Ser Thr Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Val Ala Thr Tyr Tyr Cys Gln Arg Tyr Asn Arg Ala Pro Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys Gly Gln Pro Lys Ala 100 105 110 Ala Pro Ser Val Thr Leu Phe Pro Pro Ser Ser Glu Glu Leu Gln Ala 115 120 125 Asn Lys Ala Thr Leu Val Cys Leu Ile Ser Asp Phe Tyr Pro Gly Ala 130 135 140 Val Thr Val Ala Trp Lys Ala Asp Ser Ser Pro Val Lys Ala Gly Val 145 150 155 160 Glu Thr Thr Thr Pro Ser Lys Gln Ser Asn Asn Lys Tyr Ala Ala Ser 165 170 175 Ser Tyr Leu Ser Leu Thr Pro Glu Gln Trp Lys Ser His Arg Ser Tyr 180 185 190 Ser Cys Gln Val Thr His Glu Gly Ser Thr Val Glu Lys Thr Val Ala 195 200 205 Pro Thr Glu Cys Ser 210 <210> 62 <211> 570 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 62 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser Gly Tyr Ser Phe Thr Ser Tyr 20 25 30 Trp Ile His Trp Ile Lys Gln Arg Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Met Ile Asp Pro Ser Asp Gly Glu Thr Arg Leu Asn Gln Arg Phe 50 55 60 Gln Gly Arg Ala Thr Leu Thr Val Asp Glu Ser Thr Ser Thr Ala Tyr 65 70 75 80 Met Gln Leu Arg Ser Pro Thr Ser Glu Asp Ser Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Leu Lys Glu Tyr Gly Asn Tyr Asp Ser Phe Tyr Phe Asp Val 100 105 110 Trp Gly Ala Gly Thr Leu Val Thr Val Ser Ser Glu Val Gln Leu Lys 115 120 125 Glu Ser Gly Pro Gly Leu Val Ala Pro Gly Gly Ser Leu Ser Ile Thr 130 135 140 Cys Thr Val Ser Gly Phe Ser Leu Thr Asp Ser Ser Ile Asn Trp Val 145 150 155 160 Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu Gly Met Ile Trp Gly 165 170 175 Asp Gly Arg Ile Asp Tyr Ala Asp Ala Leu Lys Ser Arg Leu Ser Ile 180 185 190 Ser Lys Asp Ser Ser Lys Ser Gln Val Phe Leu Glu Met Thr Ser Leu 195 200 205 Arg Thr Asp Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Asp Gly Tyr Phe 210 215 220 Pro Tyr Ala Met Asp Phe Trp Gly Gln Gly Thr Ser Val Thr Val Ser 225 230 235 240 Ser Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala Pro Ser Ser 245 250 255 Lys Ser Thr Ser Gly Gly Thr Ala Ala Leu Gly Cys Leu Val Lys Asp 260 265 270 Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly Ala Leu Thr 275 280 285 Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser Gly Leu Tyr 290 295 300 Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr Gln 305 310 315 320 Thr Tyr Ile Cys Asn Val Asn His Lys Pro Ser Asn Thr Lys Val Asp 325 330 335 Lys Lys Val Glu Pro Lys Ser Cys Asp Lys Thr His Thr Cys Pro Pro 340 345 350 Cys Pro Ala Pro Glu Leu Leu Gly Gly Pro Ser Val Phe Leu Phe Pro 355 360 365 Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr 370 375 380 Cys Val Val Val Asp Val Ser His Glu Asp Pro Glu Val Lys Phe Asn 385 390 395 400 Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg 405 410 415 Glu Glu Gln Tyr Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val 420 425 430 Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser 435 440 445 Asn Lys Ala Leu Pro Ala Pro Ile Glu Lys Thr Ile Ser Lys Ala Lys 450 455 460 Gly Gln Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Cys Arg Asp 465 470 475 480 Glu Leu Thr Lys Asn Gln Val Ser Leu Trp Cys Leu Val Lys Gly Phe 485 490 495 Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu 500 505 510 Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe 515 520 525 Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg Trp Gln Gln Gly 530 535 540 Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn Arg Phe 545 550 555 560 Thr Gln Lys Ser Leu Ser Leu Ser Pro Gly 565 570 <210> 63 <211> 345 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 63 Asp Ile Val Leu Thr Gln Ser Pro Ala Ser Leu Ala Val Ser Leu Gly 1 5 10 15 Gln Arg Ala Thr Ile Ser Cys Arg Ala Ser Glu Ser Val Asp Ser Tyr 20 25 30 Gly Gln Ser Tyr Met His Trp Tyr Gln Gln Lys Ala Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Tyr Leu Ala Ser Asn Leu Glu Ser Gly Val Pro Ala 50 55 60 Arg Phe Ser Gly Ser Gly Ser Arg Thr Asp Phe Thr Leu Thr Ile Asp 65 70 75 80 Pro Val Gln Ala Glu Asp Ala Ala Thr Tyr Tyr Cys Gln Gln Asn Ala 85 90 95 Glu Asp Ser Arg Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Gly 100 105 110 Gly Ser Gly Ser Ser Gly Ser Gly Gly Asp Ile Gln Met Thr Gln Ser 115 120 125 Pro Ala Ser Leu Ser Val Ser Val Gly Asp Thr Ile Thr Leu Thr Cys 130 135 140 His Ala Ser Gln Asn Ile Asp Val Trp Leu Ser Trp Phe Gln Gln Lys 145 150 155 160 Pro Gly Asn Ile Pro Lys Leu Leu Ile Tyr Lys Ala Ser Asn Leu His 165 170 175 Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe 180 185 190 Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr Tyr Tyr 195 200 205 Cys Gln Gln Ala His Ser Tyr Pro Phe Thr Phe Gly Gly Gly Thr Lys 210 215 220 Leu Glu Ile Lys Gly Gly Ser Gly Ser Ser Gly Ser Gly Gly Arg Thr 225 230 235 240 Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu 245 250 255 Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro 260 265 270 Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly 275 280 285 Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr 290 295 300 Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His 305 310 315 320 Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val 325 330 335 Thr Lys Ser Phe Asn Arg Gly Glu Cys 340 345 <210> 64 <211> 1350 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 64 gaggtgcagc tggtggaaag cggcggagga ctggtgcagc ccggcagaag cctgagactg 60 agctgcgccg ccagcggctt caccttcgac gactacgcca tgcactgggt ccgccaggcc 120 cctggcaagg gcctggaatg ggtgtccgcc atcacctgga acagcggcca catcgactac 180 gccgacagcg tggaaggccg gttcaccatc agccgggaca acgccaagaa cagcctgtac 240 ctgcagatga acagcctgcg ggccgaggac accgccgtgt actactgcgc caaggtgtcc 300 tacctgagca ccgccagcag cctggactac tggggccagg gcaccctggt gacagtgtcc 360 agcgcttcca ccaagggccc cagcgtgttc cccctggccc ctagcagcaa gagcacatct 420 ggcggcacag ccgccctggg ctgcctggtc aaggactact tccccgagcc cgtgacagtg 480 tcctggaact ctggcgccct gaccagcgga gtgcatacct tccctgccgt gctgcagtcc 540 agcggcctgt acagcctgag cagcgtggtc acagtgccca gcagcagcct gggcacccag 600 acctacatct gcaacgtgaa ccacaagccc agcaacacca aggtggacaa gaaggtggaa 660 cccaagagct gcgacaagac ccacacctgt cccccctgcc ctgcccctga actgctgggc 720 ggaccctccg tgttcctgtt ccccccaaag cccaaggaca ccctgatgat cagccggacc 780 cccgaagtga cctgcgtggt ggtggacgtg tcccacgagg accctgaagt gaagttcaat 840 tggtacgtgg acggcgtgga agtgcataac gccaagacca agcccagaga ggaacagtac 900 aacagcacct accgggtggt gtccgtgctg accgtgctgc accaggactg gctgaacggc 960 aaagagtaca agtgcaaggt gtccaacaag gccctgcctg cccccatcga gaaaaccatc 1020 agcaaggcca agggccagcc tagagagccc caagtctgca ccctgccccc cagcagagat 1080 gagctgacca agaaccaggt gtccctgagc tgcgccgtga agggcttcta ccccagcgat 1140 atcgccgtgg aatgggagag caacggccag cccgagaaca actacaagac caccccccct 1200 gtgctggaca gcgacggctc attcttcctg gtgtccaagc tgacagtgga caagagccgg 1260 tggcagcagg gcaacgtgtt cagctgcagc gtgatgcacg aggccctgca caaccattac 1320 acccagaagt ccctgagcct gagccccggc 1350 <210> 65 <211> 639 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 65 gacatccaga tgacccagag ccccagcagc ctgagcgcca gcgtgggcga cagagtgacc 60 atcacctgtc gggccagcca gggcatccgg aactacctgg cctggtatca gcagaagccc 120 ggcaaggccc ccaagctgct gatctacgcc gccagcacac tgcagagcgg cgtgcccagc 180 agattcagcg gcagcggctc cggcaccgac ttcaccctga ccatcagcag cctgcagccc 240 gaggacgtgg ccacctacta ctgccagcgg tacaacagag ccccctacac cttcggccag 300 ggcaccaagg tggaaatcaa gggacagccc aaggctgccc cctcggtcac cctgttcccc 360 ccaagcagcg aggaactgca ggccaacaag gccaccctcg tgtgcctgat cagcgacttc 420 taccctggcg ccgtgaccgt ggcctggaag gccgatagct ctcccgtgaa ggccggcgtg 480 gaaaccacca cccccagcaa gcagagcaac aacaaatacg ccgcctccag ctacctgagc 540 ctgacccccg agcagtggaa gtcccaccgg tcctacagct gccaggtcac acacgagggc 600 agcaccgtgg aaaagaccgt ggcccccacc gagtgcagc 639 <210> 66 <211> 1710 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 66 caggtgcagc tgcagcagag cggccctgag ctggtcaagc ctggcgccag cgtgaagatc 60 agctgcaagg ccagcggcta cagcttcacc agctactgga tccactggat caagcagcgg 120 cctggccagg gcctggaatg gatcggcatg atcgacccca gcgacggcga gacacggctg 180 aaccagagat tccagggcag agccaccctg accgtggacg agagcaccag caccgcctac 240 atgcagctgc ggagccccac cagcgaggac agcgccgtgt actactgcac ccggctgaaa 300 gagtacggca actacgacag cttctacttc gacgtgtggg gagccggcac cctggtcacc 360 gtgtccagcg aagtgcagct gaaagaaagc ggccctggcc tggtggcccc tggcggcagc 420 ctgagcatca cctgtaccgt gtccggcttc agcctgaccg acagcagcat caactgggtc 480 cgacagcccc ctggcaaggg cctcgagtgg ctgggaatga tctggggcga cggccggatc 540 gactacgccg acgccctgaa gtcccggctg agcatcagca aggacagcag caagagccag 600 gtgttcctgg aaatgaccag cctgcggacc gacgacaccg ccacctacta ctgcgccagg 660 gacggctact tcccctacgc catggatttc tggggccagg gcaccagcgt gaccgtgtcc 720 tctgcttcca ccaagggccc cagcgtgttc cctctggccc ctagcagcaa gagcacatct 780 ggcggaacag ccgccctggg ctgcctggtc aaggactact ttcccgagcc cgtgaccgtg 840 tcctggaact ctggtgccct gacaagcgga gtgcatacct tccctgccgt gctgcagagc 900 agcggcctgt actctctgag cagcgtggtc accgtgccaa gcagcagcct gggcacccag 960 acctacatct gcaacgtgaa ccacaagccc tccaacacca aggtggacaa gaaggtggaa 1020 cccaagagct gcgacaagac ccacacctgt cctccctgtc ctgcccctga actgctgggc 1080 ggaccctccg tgttcctgtt ccctccaaag cccaaggata ccctgatgat cagccggacc 1140 cctgaagtga cctgcgtggt ggtggacgtg tcccacgagg atcccgaagt gaagttcaat 1200 tggtacgtgg acggcgtgga agtgcataac gccaagacca agcccagaga ggaacagtac 1260 aacagcacct accgggtggt gtccgtgctg acagtgctgc accaggactg gctgaacggc 1320 aaagagtaca agtgcaaggt gtccaacaag gccctgccag cccctatcga gaaaaccatc 1380 agcaaggcca agggccagcc ccgcgagcct caggtgtaca cactgcctcc atgccgggac 1440 gagctgacca agaaccaggt gtccctgtgg tgcctcgtga agggcttcta cccctccgat 1500 atcgccgtgg aatgggagag caacggccag cccgagaaca actacaagac cacccctccc 1560 gtgctggaca gcgacggctc attcttcctg tacagcaagc tgaccgtgga caagtcccgg 1620 tggcagcagg gcaacgtgtt cagctgctct gtgatgcacg aggccctgca caaccggttc 1680 acccagaagt ccctgagcct gagccctggc 1710 <210> 67 <211> 1035 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 67 gacatcgtgc tgacccagag ccctgccagc ctggccgtgt ctctgggcca gagagccacc 60 atcagctgcc gggccagcga gagcgtggac agctacggcc agagctacat gcactggtat 120 cagcagaagg ccggccagcc ccccaagctg ctgatctacc tggccagcaa cctggaaagc 180 ggcgtgcccg ccagattcag cggcagcggc agcagaaccg acttcaccct gaccatcgac 240 cccgtgcagg ccgaggacgc cgccacctac tactgccagc agaacgccga ggacagccgg 300 accttcggcg gaggcaccaa gctggaaatc aagggcggct ccggcagcag cggctctggc 360 ggcgatatcc agatgaccca gtcccccgcc tccctgagcg tgtccgtggg cgacaccatc 420 accctgacat gccacgccag ccagaacatc gacgtgtggc tgagctggtt ccagcagaag 480 cctggcaaca tccctaagct gctcatctat aaggcctcca acctgcacac cggcgtgccc 540 agcaggtttt ccggctctgg cagcggcacc ggctttaccc tgacaatcag cagcctgcag 600 cccgaggata tcgccacata ttactgtcag caggcccaca gctacccctt cacctttggc 660 ggcggaacaa agctcgagat taagggcggc agcggaagct ccggctccgg cggacgtacg 720 gtggccgctc cttccgtgtt catcttccct ccctccgacg agcagctgaa gtccggcacc 780 gcctccgtgg tgtgtctgct gaacaacttc taccctcggg aggccaaggt gcagtggaag 840 gtggacaacg ccctgcagtc cggcaactcc caggagtccg tcaccgagca ggactccaag 900 gacagcacct actccctgtc ctccaccctg accctgtcca aggccgacta cgagaagcac 960 aaggtgtacg cctgtgaggt gacccaccag ggcctgtcca gccctgtgac caagtccttc 1020 aaccggggcg agtgc 1035 <210> 68 <211> 570 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 68 Glu Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala Pro Gly Gly 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Thr Asp Ser 20 25 30 Ser Ile Asn Trp Val Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Met Ile Trp Gly Asp Gly Arg Ile Asp Tyr Ala Asp Ala Leu Lys 50 55 60 Ser Arg Leu Ser Ile Ser Lys Asp Ser Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Glu Met Thr Ser Leu Arg Thr Asp Asp Thr Ala Thr Tyr Tyr Cys Ala 85 90 95 Arg Asp Gly Tyr Phe Pro Tyr Ala Met Asp Phe Trp Gly Gln Gly Thr 100 105 110 Ser Val Thr Val Ser Ser Gln Val Gln Leu Gln Gln Ser Gly Pro Glu 115 120 125 Leu Val Lys Pro Gly Ala Ser Val Lys Ile Ser Cys Lys Ala Ser Gly 130 135 140 Tyr Ser Phe Thr Ser Tyr Trp Ile His Trp Ile Lys Gln Arg Pro Gly 145 150 155 160 Gln Gly Leu Glu Trp Ile Gly Met Ile Asp Pro Ser Asp Gly Glu Thr 165 170 175 Arg Leu Asn Gln Arg Phe Gln Gly Arg Ala Thr Leu Thr Val Asp Glu 180 185 190 Ser Thr Ser Thr Ala Tyr Met Gln Leu Arg Ser Pro Thr Ser Glu Asp 195 200 205 Ser Ala Val Tyr Tyr Cys Thr Arg Leu Lys Glu Tyr Gly Asn Tyr Asp 210 215 220 Ser Phe Tyr Phe Asp Val Trp Gly Ala Gly Thr Leu Val Thr Val Ser 225 230 235 240 Ser Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala Pro Ser Ser 245 250 255 Lys Ser Thr Ser Gly Gly Thr Ala Ala Leu Gly Cys Leu Val Lys Asp 260 265 270 Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly Ala Leu Thr 275 280 285 Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser Gly Leu Tyr 290 295 300 Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr Gln 305 310 315 320 Thr Tyr Ile Cys Asn Val Asn His Lys Pro Ser Asn Thr Lys Val Asp 325 330 335 Lys Lys Val Glu Pro Lys Ser Cys Asp Lys Thr His Thr Cys Pro Pro 340 345 350 Cys Pro Ala Pro Glu Leu Leu Gly Gly Pro Ser Val Phe Leu Phe Pro 355 360 365 Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr 370 375 380 Cys Val Val Val Asp Val Ser His Glu Asp Pro Glu Val Lys Phe Asn 385 390 395 400 Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg 405 410 415 Glu Glu Gln Tyr Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val 420 425 430 Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser 435 440 445 Asn Lys Ala Leu Pro Ala Pro Ile Glu Lys Thr Ile Ser Lys Ala Lys 450 455 460 Gly Gln Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Cys Arg Asp 465 470 475 480 Glu Leu Thr Lys Asn Gln Val Ser Leu Trp Cys Leu Val Lys Gly Phe 485 490 495 Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu 500 505 510 Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe 515 520 525 Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg Trp Gln Gln Gly 530 535 540 Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn Arg Phe 545 550 555 560 Thr Gln Lys Ser Leu Ser Leu Ser Pro Gly 565 570 <210> 69 <211> 345 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 69 Asp Ile Gln Met Thr Gln Ser Pro Ala Ser Leu Ser Val Ser Val Gly 1 5 10 15 Asp Thr Ile Thr Leu Thr Cys His Ala Ser Gln Asn Ile Asp Val Trp 20 25 30 Leu Ser Trp Phe Gln Gln Lys Pro Gly Asn Ile Pro Lys Leu Leu Ile 35 40 45 Tyr Lys Ala Ser Asn Leu His Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Ala His Ser Tyr Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Gly Gly Ser Gly Ser 100 105 110 Ser Gly Ser Gly Gly Asp Ile Val Leu Thr Gln Ser Pro Ala Ser Leu 115 120 125 Ala Val Ser Leu Gly Gln Arg Ala Thr Ile Ser Cys Arg Ala Ser Glu 130 135 140 Ser Val Asp Ser Tyr Gly Gln Ser Tyr Met His Trp Tyr Gln Gln Lys 145 150 155 160 Ala Gly Gln Pro Pro Lys Leu Leu Ile Tyr Leu Ala Ser Asn Leu Glu 165 170 175 Ser Gly Val Pro Ala Arg Phe Ser Gly Ser Gly Ser Arg Thr Asp Phe 180 185 190 Thr Leu Thr Ile Asp Pro Val Gln Ala Glu Asp Ala Ala Thr Tyr Tyr 195 200 205 Cys Gln Gln Asn Ala Glu Asp Ser Arg Thr Phe Gly Gly Gly Thr Lys 210 215 220 Leu Glu Ile Lys Gly Gly Ser Gly Ser Ser Gly Ser Gly Gly Arg Thr 225 230 235 240 Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu 245 250 255 Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro 260 265 270 Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly 275 280 285 Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr 290 295 300 Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His 305 310 315 320 Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val 325 330 335 Thr Lys Ser Phe Asn Arg Gly Glu Cys 340 345 <210> 70 <211> 1035 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 70 gacatccaga tgacccagag ccccgccagc ctgagcgtgt ccgtgggcga taccatcacc 60 ctgacctgcc acgccagcca gaacatcgac gtgtggctga gctggttcca gcagaagccc 120 ggcaacatcc ccaagctgct gatctacaag gccagcaacc tgcacaccgg cgtgcccagc 180 agattcagcg gctctggcag cggcaccggc tttaccctga ccatcagcag cctgcagccc 240 gaggatatcg ccacctacta ctgccagcag gcccacagct accccttcac cttcggcgga 300 ggcaccaagc tggaaatcaa gggcggcagc ggcagctccg gctctggcgg cgatatcgtg 360 ctgacccagt ctcccgcctc cctggccgtg tctctgggcc agagagccac catcagctgc 420 cgggccagcg agagcgtgga cagctacggc cagagctaca tgcactggta tcagcagaag 480 gccggacagc cccctaaact gctcatctac ctggcctcca acctggaaag cggcgtgccc 540 gccaggtttt ccggcagcgg ctccagaacc gacttcaccc tgacaatcga ccccgtgcag 600 gccgaggacg ccgccacata ttactgtcag cagaacgccg aggacagcag aacctttggc 660 ggcggaacaa agctcgagat taagggcggc tccggctcca gcggatctgg cggacgtacg 720 gtggccgctc cttccgtgtt catcttccct ccctccgacg agcagctgaa gtccggcacc 780 gcctccgtgg tgtgtctgct gaacaacttc taccctcggg aggccaaggt gcagtggaag 840 gtggacaacg ccctgcagtc cggcaactcc caggagtccg tcaccgagca ggactccaag 900 gacagcacct actccctgtc ctccaccctg accctgtcca aggccgacta cgagaagcac 960 aaggtgtacg cctgtgaggt gacccaccag ggcctgtcca gccctgtgac caagtccttc 1020 aaccggggcg agtgc 1035 <210> 71 <211> 214 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 71 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Arg Asn Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Ala Ala Ser Thr Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Val Ala Thr Tyr Tyr Cys Gln Arg Tyr Asn Arg Ala Pro Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys Arg Thr Val Ala Ala 100 105 110 Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly 115 120 125 Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala 130 135 140 Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln 145 150 155 160 Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser 165 170 175 Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr 180 185 190 Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser 195 200 205 Phe Asn Arg Gly Glu Cys 210 <210> 72 <211> 642 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 72 gacatccaga tgacccagag ccccagcagc ctgagcgcca gcgtgggcga cagagtgacc 60 atcacctgtc gggccagcca gggcatccgg aactacctgg cctggtatca gcagaagccc 120 ggcaaggccc ccaagctgct gatctacgcc gccagcacac tgcagagcgg cgtgcccagc 180 agattcagcg gcagcggctc cggcaccgac ttcaccctga ccatcagcag cctgcagccc 240 gaggacgtgg ccacctacta ctgccagcgg tacaacagag ccccctacac cttcggccag 300 ggcaccaagg tggaaatcaa gcgtacggtg gccgctcctt ccgtgttcat cttccctccc 360 tccgacgagc agctgaagtc cggcaccgcc tccgtggtgt gtctgctgaa caacttctac 420 cctcgggagg ccaaggtgca gtggaaggtg gacaacgccc tgcagtccgg caactcccag 480 gagtccgtca ccgagcagga ctccaaggac agcacctact ccctgtcctc caccctgacc 540 ctgtccaagg ccgactacga gaagcacaag gtgtacgcct gtgaggtgac ccaccagggc 600 ctgtccagcc ctgtgaccaa gtccttcaac cggggcgagt gc 642 <210> 73 <211> 447 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 73 Glu Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala Pro Gly Gly 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Thr Asp Ser 20 25 30 Ser Ile Asn Trp Val Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Met Ile Trp Gly Asp Gly Arg Ile Asp Tyr Ala Asp Ala Leu Lys 50 55 60 Ser Arg Leu Ser Ile Ser Lys Asp Ser Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Glu Met Thr Ser Leu Arg Thr Asp Asp Thr Ala Thr Tyr Tyr Cys Ala 85 90 95 Arg Asp Gly Tyr Phe Pro Tyr Ala Met Asp Phe Trp Gly Gln Gly Thr 100 105 110 Ser Val Thr Val Ser Ser Ala Ser Thr Lys Gly Pro Ser Val Phe Pro 115 120 125 Leu Ala Pro Ser Ser Lys Ser Thr Ser Gly Gly Thr Ala Ala Leu Gly 130 135 140 Cys Leu Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn 145 150 155 160 Ser Gly Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln 165 170 175 Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser 180 185 190 Ser Leu Gly Thr Gln Thr Tyr Ile Cys Asn Val Asn His Lys Pro Ser 195 200 205 Asn Thr Lys Val Asp Lys Lys Val Glu Pro Lys Ser Cys Asp Lys Thr 210 215 220 His Thr Cys Pro Pro Cys Pro Ala Pro Glu Leu Leu Gly Gly Pro Ser 225 230 235 240 Val Phe Leu Phe Pro Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg 245 250 255 Thr Pro Glu Val Thr Cys Val Val Val Asp Val Ser His Glu Asp Pro 260 265 270 Glu Val Lys Phe Asn Trp Tyr Val Asp Gly Val Glu Val His Asn Ala 275 280 285 Lys Thr Lys Pro Arg Glu Glu Gln Tyr Asn Ser Thr Tyr Arg Val Val 290 295 300 Ser Val Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr 305 310 315 320 Lys Cys Lys Val Ser Asn Lys Ala Leu Pro Ala Pro Ile Glu Lys Thr 325 330 335 Ile Ser Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln Val Cys Thr Leu 340 345 350 Pro Pro Ser Arg Asp Glu Leu Thr Lys Asn Gln Val Ser Leu Ser Cys 355 360 365 Ala Val Lys Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser 370 375 380 Asn Gly Gln Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp 385 390 395 400 Ser Asp Gly Ser Phe Phe Leu Val Ser Lys Leu Thr Val Asp Lys Ser 405 410 415 Arg Trp Gln Gln Gly Asn Val Phe Ser Cys Ser Val Met His Glu Ala 420 425 430 Leu His Asn His Tyr Thr Gln Lys Ser Leu Ser Leu Ser Pro Gly 435 440 445 <210> 74 <211> 217 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 74 Asp Ile Val Leu Thr Gln Ser Pro Ala Ser Leu Ala Val Ser Leu Gly 1 5 10 15 Gln Arg Ala Thr Ile Ser Cys Arg Ala Ser Glu Ser Val Asp Ser Tyr 20 25 30 Gly Gln Ser Tyr Met His Trp Tyr Gln Gln Lys Ala Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Tyr Leu Ala Ser Asn Leu Glu Ser Gly Val Pro Ala 50 55 60 Arg Phe Ser Gly Ser Gly Ser Arg Thr Asp Phe Thr Leu Thr Ile Asp 65 70 75 80 Pro Val Gln Ala Glu Asp Ala Ala Thr Tyr Tyr Cys Gln Gln Asn Ala 85 90 95 Glu Asp Ser Arg Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Gly 100 105 110 Gln Pro Lys Ala Ala Pro Ser Val Thr Leu Phe Pro Pro Ser Ser Glu 115 120 125 Glu Leu Gln Ala Asn Lys Ala Thr Leu Val Cys Leu Ile Ser Asp Phe 130 135 140 Tyr Pro Gly Ala Val Thr Val Ala Trp Lys Ala Asp Ser Ser Pro Val 145 150 155 160 Lys Ala Gly Val Glu Thr Thr Thr Pro Ser Lys Gln Ser Asn Asn Lys 165 170 175 Tyr Ala Ala Ser Ser Tyr Leu Ser Leu Thr Pro Glu Gln Trp Lys Ser 180 185 190 His Arg Ser Tyr Ser Cys Gln Val Thr His Glu Gly Ser Thr Val Glu 195 200 205 Lys Thr Val Ala Pro Thr Glu Cys Ser 210 215 <210> 75 <211> 573 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 75 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser Gly Tyr Ser Phe Thr Ser Tyr 20 25 30 Trp Ile His Trp Ile Lys Gln Arg Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Met Ile Asp Pro Ser Asp Gly Glu Thr Arg Leu Asn Gln Arg Phe 50 55 60 Gln Gly Arg Ala Thr Leu Thr Val Asp Glu Ser Thr Ser Thr Ala Tyr 65 70 75 80 Met Gln Leu Arg Ser Pro Thr Ser Glu Asp Ser Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Leu Lys Glu Tyr Gly Asn Tyr Asp Ser Phe Tyr Phe Asp Val 100 105 110 Trp Gly Ala Gly Thr Leu Val Thr Val Ser Ser Glu Val Gln Leu Val 115 120 125 Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Arg Ser Leu Arg Leu Ser 130 135 140 Cys Ala Ala Ser Gly Phe Thr Phe Asp Asp Tyr Ala Met His Trp Val 145 150 155 160 Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val Ser Ala Ile Thr Trp 165 170 175 Asn Ser Gly His Ile Asp Tyr Ala Asp Ser Val Glu Gly Arg Phe Thr 180 185 190 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 195 200 205 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Ser Tyr 210 215 220 Leu Ser Thr Ala Ser Ser Leu Asp Tyr Trp Gly Gln Gly Thr Leu Val 225 230 235 240 Thr Val Ser Ser Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala 245 250 255 Pro Ser Ser Lys Ser Thr Ser Gly Gly Thr Ala Ala Leu Gly Cys Leu 260 265 270 Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly 275 280 285 Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser 290 295 300 Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu 305 310 315 320 Gly Thr Gln Thr Tyr Ile Cys Asn Val Asn His Lys Pro Ser Asn Thr 325 330 335 Lys Val Asp Lys Lys Val Glu Pro Lys Ser Cys Asp Lys Thr His Thr 340 345 350 Cys Pro Pro Cys Pro Ala Pro Glu Leu Leu Gly Gly Pro Ser Val Phe 355 360 365 Leu Phe Pro Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro 370 375 380 Glu Val Thr Cys Val Val Val Asp Val Ser His Glu Asp Pro Glu Val 385 390 395 400 Lys Phe Asn Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys Thr 405 410 415 Lys Pro Arg Glu Glu Gln Tyr Asn Ser Thr Tyr Arg Val Val Ser Val 420 425 430 Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys 435 440 445 Lys Val Ser Asn Lys Ala Leu Pro Ala Pro Ile Glu Lys Thr Ile Ser 450 455 460 Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro 465 470 475 480 Cys Arg Asp Glu Leu Thr Lys Asn Gln Val Ser Leu Trp Cys Leu Val 485 490 495 Lys Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly 500 505 510 Gln Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp 515 520 525 Gly Ser Phe Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg Trp 530 535 540 Gln Gln Gly Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu His 545 550 555 560 Asn Arg Phe Thr Gln Lys Ser Leu Ser Leu Ser Pro Gly 565 570 <210> 76 <211> 341 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 76 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Arg Asn Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Ala Ala Ser Thr Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Val Ala Thr Tyr Tyr Cys Gln Arg Tyr Asn Arg Ala Pro Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys Gly Gly Ser Gly Ser 100 105 110 Ser Gly Ser Gly Gly Asp Ile Gln Met Thr Gln Ser Pro Ala Ser Leu 115 120 125 Ser Val Ser Val Gly Asp Thr Ile Thr Leu Thr Cys His Ala Ser Gln 130 135 140 Asn Ile Asp Val Trp Leu Ser Trp Phe Gln Gln Lys Pro Gly Asn Ile 145 150 155 160 Pro Lys Leu Leu Ile Tyr Lys Ala Ser Asn Leu His Thr Gly Val Pro 165 170 175 Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile 180 185 190 Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Ala 195 200 205 His Ser Tyr Pro Phe Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 210 215 220 Gly Gly Ser Gly Ser Ser Gly Ser Gly Gly Arg Thr Val Ala Ala Pro 225 230 235 240 Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly Thr 245 250 255 Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala Lys 260 265 270 Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln Glu 275 280 285 Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser Ser 290 295 300 Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr Ala 305 310 315 320 Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser Phe 325 330 335 Asn Arg Gly Glu Cys 340 <210> 77 <211> 1341 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 77 gaggtgcagc tgaaggagag cggccccggc ctggtggccc ccggcggcag cctgagcatc 60 acctgcaccg tgagcggctt cagcctgacc gacagcagca tcaactgggt gcgccagccc 120 cccggcaagg gcctggagtg gctgggcatg atctggggcg acggccgcat cgactacgcc 180 gacgccctga agagccgcct gagcatcagc aaggacagca gcaagagcca ggtgttcctg 240 gagatgacca gcctgcgcac cgacgacacc gccacctact actgcgcccg cgacggctac 300 ttcccctacg ccatggactt ctggggccag ggcaccagcg tgaccgtgag cagcgccagc 360 accaagggcc ccagcgtgtt ccccctggcc cctagcagca agagcacatc tggcggcaca 420 gccgccctgg gctgcctggt caaggactac ttccccgagc ccgtgacagt gtcctggaac 480 tctggcgccc tgaccagcgg agtgcatacc ttccctgccg tgctgcagtc cagcggcctg 540 tacagcctga gcagcgtggt cacagtgccc agcagcagcc tgggcaccca gacctacatc 600 tgcaacgtga accacaagcc cagcaacacc aaggtggaca agaaggtgga acccaagagc 660 tgcgacaaga cccacacctg tcccccctgc cctgcccctg aactgctggg cggaccctcc 720 gtgttcctgt tccccccaaa gcccaaggac accctgatga tcagccggac ccccgaagtg 780 acctgcgtgg tggtggacgt gtcccacgag gaccctgaag tgaagttcaa ttggtacgtg 840 gacggcgtgg aagtgcataa cgccaagacc aagcccagag aggaacagta caacagcacc 900 taccgggtgg tgtccgtgct gaccgtgctg caccaggact ggctgaacgg caaagagtac 960 aagtgcaagg tgtccaacaa ggccctgcct gcccccatcg agaaaaccat cagcaaggcc 1020 aagggccagc ctagagagcc ccaagtctgc accctgcccc ccagcagaga tgagctgacc 1080 aagaaccagg tgtccctgag ctgcgccgtg aagggcttct accccagcga tatcgccgtg 1140 gaatgggaga gcaacggcca gcccgagaac aactacaaga ccaccccccc tgtgctggac 1200 agcgacggct cattcttcct ggtgtccaag ctgacagtgg acaagagccg gtggcagcag 1260 ggcaacgtgt tcagctgcag cgtgatgcac gaggccctgc acaaccatta cacccagaag 1320 tccctgagcc tgagccccgg c 1341 <210> 78 <211> 651 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 78 gacatcgtgc tgacccagag ccctgccagc ctggccgtgt ctctgggcca gagagccacc 60 atcagctgcc gggccagcga gagcgtggac agctacggcc agagctacat gcactggtat 120 cagcagaagg ccggccagcc ccccaagctg ctgatctacc tggccagcaa cctggaaagc 180 ggcgtgcccg ccagattcag cggcagcggc agcagaaccg acttcaccct gaccatcgac 240 cccgtgcagg ccgaggacgc cgccacctac tactgccagc agaacgccga ggacagccgg 300 accttcggcg gaggcaccaa gctggaaatc aagggacagc ccaaggctgc cccctcggtc 360 accctgttcc ccccaagcag cgaggaactg caggccaaca aggccaccct cgtgtgcctg 420 atcagcgact tctaccctgg cgccgtgacc gtggcctgga aggccgatag ctctcccgtg 480 aaggccggcg tggaaaccac cacccccagc aagcagagca acaacaaata cgccgccagc 540 agctacctga gcctgacccc cgagcagtgg aagtcccacc ggtcctacag ctgccaggtc 600 acacacgagg gcagcaccgt ggaaaagacc gtggccccca ccgagtgcag c 651 <210> 79 <211> 1719 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 79 caggtgcagc tgcagcagag cggccctgag ctggtcaagc ctggcgccag cgtgaagatc 60 agctgcaagg ccagcggcta cagcttcacc agctactgga tccactggat caagcagcgg 120 cctggccagg gcctggaatg gatcggcatg atcgacccca gcgacggcga gacacggctg 180 aaccagagat tccagggcag agccaccctg accgtggacg agagcaccag caccgcctac 240 atgcagctgc ggagccccac cagcgaggac agcgccgtgt actactgcac ccggctgaaa 300 gagtacggca actacgacag cttctacttc gacgtgtggg gagccggcac cctggtcacc 360 gtgtccagcg aagtgcagct ggtggaaagc ggcggaggcc tggtgcagcc cggcagaagc 420 ctgagactga gctgcgccgc cagcggcttc accttcgacg actacgccat gcactgggtc 480 cgacaggccc ctggcaaagg actggaatgg gtgtccgcca tcacctggaa cagcggccac 540 atcgactacg ccgacagcgt ggaaggccgg ttcaccatca gccgggacaa cgccaagaac 600 agcctgtacc tgcagatgaa cagcctgcgg gccgaggata ccgccgtgta ttattgcgcc 660 aaggtgtcct acctgagcac cgccagcagc ctggactact ggggccaggg caccctcgtg 720 acagtgtcct ccgcttccac caagggcccc agcgtgttcc ctctggcccc tagcagcaag 780 agcacatctg gcggaacagc cgccctgggc tgcctggtca aggactactt tcccgagccc 840 gtgaccgtgt cctggaactc tggtgccctg acaagcggag tgcatacctt ccctgccgtg 900 ctgcagagca gcggcctgta ctctctgagc agcgtggtca ccgtgccaag cagcagcctg 960 ggcacccaga cctacatctg caacgtgaac cacaagccct ccaacaccaa ggtggacaag 1020 aaggtggaac ccaagagctg cgacaagacc cacacctgtc ctccctgtcc tgcccctgaa 1080 ctgctgggcg gaccctccgt gttcctgttc cctccaaagc ccaaggatac cctgatgatc 1140 agccggaccc ctgaagtgac ctgcgtggtg gtggacgtgt cccacgagga tcccgaagtg 1200 aagttcaatt ggtacgtgga cggcgtggaa gtgcataacg ccaagaccaa gcccagagag 1260 gaacagtaca acagcaccta ccgggtggtg tccgtgctga cagtgctgca ccaggactgg 1320 ctgaacggca aagagtacaa gtgcaaggtg tccaacaagg ccctgccagc ccctatcgag 1380 aaaaccatca gcaaggccaa gggccagccc cgcgagcctc aggtgtacac actgcctcca 1440 tgccgggacg agctgaccaa gaaccaggtg tccctgtggt gcctcgtgaa gggcttctac 1500 ccctccgata tcgccgtgga atgggagagc aacggccagc ccgagaacaa ctacaagacc 1560 acccctcccg tgctggacag cgacggctca ttcttcctgt acagcaagct gaccgtggac 1620 aagtcccggt ggcagcaggg caacgtgttc agctgctctg tgatgcacga ggccctgcac 1680 aaccggttca cccagaagtc cctgagcctg agccctggc 1719 <210> 80 <211> 1023 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 80 gacatccaga tgacccagag ccccagcagc ctgagcgcca gcgtgggcga cagagtgacc 60 atcacctgtc gggccagcca gggcatccgg aactacctgg cctggtatca gcagaagccc 120 ggcaaggccc ccaagctgct gatctacgcc gccagcacac tgcagagcgg cgtgcccagc 180 agattcagcg gcagcggctc cggcaccgac ttcaccctga ccatcagcag cctgcagccc 240 gaggacgtgg ccacctacta ctgccagcgg tacaacagag ccccctacac cttcggccag 300 ggcaccaagg tggaaatcaa gggcggctct ggcagctccg gcagcggcgg agacattcag 360 atgacacagt cccccgccag cctgtccgtg tccgtgggcg ataccatcac cctgacatgc 420 cacgccagcc agaacatcga cgtgtggctg agctggttcc agcagaaacc tggcaacatc 480 cctaagctgc tcatctataa ggccagcaac ctgcacacag gcgtgccctc cagattctcc 540 ggctctggct ctggcaccgg ctttacactg acaatcagtt ctctgcagcc tgaggatatc 600 gccacatatt actgtcagca ggcccacagc taccctttca ccttcggagg cggcaccaag 660 ctcgagatta agggcggaag cggctcctcc ggctccggcg gacgtacggt ggccgctcct 720 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 780 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 840 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 900 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 960 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 1020 tgc 1023 <210> 81 <211> 573 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 81 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Asp Asp Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Ala Ile Thr Trp Asn Ser Gly His Ile Asp Tyr Ala Asp Ser Val 50 55 60 Glu Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Val Ser Tyr Leu Ser Thr Ala Ser Ser Leu Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser Gln Val Gln Leu Gln Gln Ser 115 120 125 Gly Pro Glu Leu Val Lys Pro Gly Ala Ser Val Lys Ile Ser Cys Lys 130 135 140 Ala Ser Gly Tyr Ser Phe Thr Ser Tyr Trp Ile His Trp Ile Lys Gln 145 150 155 160 Arg Pro Gly Gln Gly Leu Glu Trp Ile Gly Met Ile Asp Pro Ser Asp 165 170 175 Gly Glu Thr Arg Leu Asn Gln Arg Phe Gln Gly Arg Ala Thr Leu Thr 180 185 190 Val Asp Glu Ser Thr Ser Thr Ala Tyr Met Gln Leu Arg Ser Pro Thr 195 200 205 Ser Glu Asp Ser Ala Val Tyr Tyr Cys Thr Arg Leu Lys Glu Tyr Gly 210 215 220 Asn Tyr Asp Ser Phe Tyr Phe Asp Val Trp Gly Ala Gly Thr Leu Val 225 230 235 240 Thr Val Ser Ser Ala Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala 245 250 255 Pro Ser Ser Lys Ser Thr Ser Gly Gly Thr Ala Ala Leu Gly Cys Leu 260 265 270 Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly 275 280 285 Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val Leu Gln Ser Ser 290 295 300 Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu 305 310 315 320 Gly Thr Gln Thr Tyr Ile Cys Asn Val Asn His Lys Pro Ser Asn Thr 325 330 335 Lys Val Asp Lys Lys Val Glu Pro Lys Ser Cys Asp Lys Thr His Thr 340 345 350 Cys Pro Pro Cys Pro Ala Pro Glu Leu Leu Gly Gly Pro Ser Val Phe 355 360 365 Leu Phe Pro Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro 370 375 380 Glu Val Thr Cys Val Val Val Asp Val Ser His Glu Asp Pro Glu Val 385 390 395 400 Lys Phe Asn Trp Tyr Val Asp Gly Val Glu Val His Asn Ala Lys Thr 405 410 415 Lys Pro Arg Glu Glu Gln Tyr Asn Ser Thr Tyr Arg Val Val Ser Val 420 425 430 Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys 435 440 445 Lys Val Ser Asn Lys Ala Leu Pro Ala Pro Ile Glu Lys Thr Ile Ser 450 455 460 Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro 465 470 475 480 Cys Arg Asp Glu Leu Thr Lys Asn Gln Val Ser Leu Trp Cys Leu Val 485 490 495 Lys Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly 500 505 510 Gln Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp 515 520 525 Gly Ser Phe Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg Trp 530 535 540 Gln Gln Gly Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu His 545 550 555 560 Asn Arg Phe Thr Gln Lys Ser Leu Ser Leu Ser Pro Gly 565 570 <210> 82 <211> 341 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 82 Asp Ile Gln Met Thr Gln Ser Pro Ala Ser Leu Ser Val Ser Val Gly 1 5 10 15 Asp Thr Ile Thr Leu Thr Cys His Ala Ser Gln Asn Ile Asp Val Trp 20 25 30 Leu Ser Trp Phe Gln Gln Lys Pro Gly Asn Ile Pro Lys Leu Leu Ile 35 40 45 Tyr Lys Ala Ser Asn Leu His Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Ala His Ser Tyr Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Gly Gly Ser Gly Ser 100 105 110 Ser Gly Ser Gly Gly Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu 115 120 125 Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln 130 135 140 Gly Ile Arg Asn Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala 145 150 155 160 Pro Lys Leu Leu Ile Tyr Ala Ala Ser Thr Leu Gln Ser Gly Val Pro 165 170 175 Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile 180 185 190 Ser Ser Leu Gln Pro Glu Asp Val Ala Thr Tyr Tyr Cys Gln Arg Tyr 195 200 205 Asn Arg Ala Pro Tyr Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 210 215 220 Gly Gly Ser Gly Ser Ser Gly Ser Gly Gly Arg Thr Val Ala Ala Pro 225 230 235 240 Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly Thr 245 250 255 Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala Lys 260 265 270 Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln Glu 275 280 285 Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser Ser 290 295 300 Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr Ala 305 310 315 320 Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser Phe 325 330 335 Asn Arg Gly Glu Cys 340 <210> 83 <211> 1719 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 83 gaggtgcagc tggtggaaag cggcggagga ctggtgcagc ccggcagaag cctgagactg 60 agctgcgccg ccagcggctt caccttcgac gactacgcca tgcactgggt ccgacaggcc 120 cctggcaagg gcctggaatg ggtgtccgcc atcacctgga acagcggcca catcgactac 180 gccgacagcg tggaaggccg gttcaccatc agccgggaca acgccaagaa cagcctgtac 240 ctgcagatga acagcctgcg ggccgaggac accgccgtgt actactgcgc caaggtgtcc 300 tacctgagca ccgccagcag cctggactac tggggccagg gcaccctggt caccgtgtcc 360 agtcaggtcc agctgcagca gagcggccct gagctggtca agcctggcgc cagcgtgaag 420 atcagctgca aggccagcgg ctacagcttc accagctact ggatccactg gatcaagcag 480 cggcctggcc agggcctcga gtggatcggc atgatcgacc ccagcgacgg cgagacacgg 540 ctgaaccaga gattccaggg cagagccacc ctgaccgtgg acgagagcac cagcaccgcc 600 tacatgcagc tgcggagccc caccagcgag gatagcgccg tgtattattg cacccggctg 660 aaagagtacg gcaactacga cagcttctac ttcgacgtgt ggggagccgg caccctcgtg 720 acagtgtcct ccgcttccac caagggcccc agcgtgttcc ctctggcccc tagcagcaag 780 agcacatctg gcggaacagc cgccctgggc tgcctggtca aggactactt tcccgagccc 840 gtgaccgtgt cctggaactc tggtgccctg acaagcggag tgcatacctt ccctgccgtg 900 ctgcagagca gcggcctgta ctctctgagc agcgtggtca ccgtgccaag cagcagcctg 960 ggcacccaga cctacatctg caacgtgaac cacaagccct ccaacaccaa ggtggacaag 1020 aaggtggaac ccaagagctg cgacaagacc cacacctgtc ctccctgtcc tgcccctgaa 1080 ctgctgggcg gaccctccgt gttcctgttc cctccaaagc ccaaggatac cctgatgatc 1140 agccggaccc ctgaagtgac ctgcgtggtg gtggacgtgt cccacgagga tcccgaagtg 1200 aagttcaatt ggtacgtgga cggcgtggaa gtgcataacg ccaagaccaa gcccagagag 1260 gaacagtaca acagcaccta ccgggtggtg tccgtgctga cagtgctgca ccaggactgg 1320 ctgaacggca aagagtacaa gtgcaaggtg tccaacaagg ccctgccagc ccctatcgag 1380 aaaaccatca gcaaggccaa gggccagccc cgcgagcctc aggtgtacac actgcctcca 1440 tgccgggacg agctgaccaa gaaccaggtg tccctgtggt gcctcgtgaa gggcttctac 1500 ccctccgata tcgccgtgga atgggagagc aacggccagc ccgagaacaa ctacaagacc 1560 acccctcccg tgctggacag cgacggctca ttcttcctgt acagcaagct gaccgtggac 1620 aagtcccggt ggcagcaggg caacgtgttc agctgctctg tgatgcacga ggccctgcac 1680 aaccggttca cccagaagtc cctgagcctg agccctggc 1719 <210> 84 <211> 1023 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 84 gacatccaga tgacccagag ccccgccagc ctgagcgtgt ccgtgggcga taccatcacc 60 ctgacctgcc acgccagcca gaacatcgac gtgtggctga gctggttcca gcagaagccc 120 ggcaacatcc ccaagctgct gatctacaag gccagcaacc tgcacaccgg cgtgcccagc 180 agattcagcg gctctggcag cggcaccggc tttaccctga ccatcagcag cctgcagccc 240 gaggatatcg ccacctacta ctgccagcag gcccacagct accccttcac cttcggcgga 300 ggcaccaagc tggaaatcaa gggcggcagc ggcagctccg gcagcggcgg agacattcag 360 atgacacagt cccccagcag cctgtccgcc agcgtgggcg acagagtgac catcacctgt 420 cgggccagcc agggcatccg gaactacctg gcctggtatc agcagaaacc tggcaaggcc 480 cctaaactgc tcatctacgc cgccagcaca ctgcagtctg gcgtgccctc cagattctcc 540 ggaagcggct ccggcaccga tttcaccctg acaatctcat ctctgcagcc tgaggacgtg 600 gccacatatt actgccagag atacaacaga gccccctaca cctttggcca gggcaccaag 660 gtcgagatta agggcggatc cggctccagc ggcagcggag gacgtacggt ggccgctcct 720 tccgtgttca tcttccctcc ctccgacgag cagctgaagt ccggcaccgc ctccgtggtg 780 tgtctgctga acaacttcta ccctcgggag gccaaggtgc agtggaaggt ggacaacgcc 840 ctgcagtccg gcaactccca ggagtccgtc accgagcagg actccaagga cagcacctac 900 tccctgtcct ccaccctgac cctgtccaag gccgactacg agaagcacaa ggtgtacgcc 960 tgtgaggtga cccaccaggg cctgtccagc cctgtgacca agtccttcaa ccggggcgag 1020 tgc 1023 <210> 85 <211> 452 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 85 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser Gly Tyr Ser Phe Thr Ser Tyr 20 25 30 Trp Ile His Trp Ile Lys Gln Arg Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Met Ile Asp Pro Ser Asp Gly Glu Thr Arg Leu Asn Gln Arg Phe 50 55 60 Gln Gly Arg Ala Thr Leu Thr Val Asp Glu Ser Thr Ser Thr Ala Tyr 65 70 75 80 Met Gln Leu Arg Ser Pro Thr Ser Glu Asp Ser Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Leu Lys Glu Tyr Gly Asn Tyr Asp Ser Phe Tyr Phe Asp Val 100 105 110 Trp Gly Ala Gly Thr Leu Val Thr Val Ser Ser Ala Ser Thr Lys Gly 115 120 125 Pro Ser Val Phe Pro Leu Ala Pro Ser Ser Lys Ser Thr Ser Gly Gly 130 135 140 Thr Ala Ala Leu Gly Cys Leu Val Lys Asp Tyr Phe Pro Glu Pro Val 145 150 155 160 Thr Val Ser Trp Asn Ser Gly Ala Leu Thr Ser Gly Val His Thr Phe 165 170 175 Pro Ala Val Leu Gln Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val Val 180 185 190 Thr Val Pro Ser Ser Ser Leu Gly Thr Gln Thr Tyr Ile Cys Asn Val 195 200 205 Asn His Lys Pro Ser Asn Thr Lys Val Asp Lys Lys Val Glu Pro Lys 210 215 220 Ser Cys Asp Lys Thr His Thr Cys Pro Pro Cys Pro Ala Pro Glu Leu 225 230 235 240 Leu Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys Pro Lys Asp Thr 245 250 255 Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val Val Val Asp Val 260 265 270 Ser His Glu Asp Pro Glu Val Lys Phe Asn Trp Tyr Val Asp Gly Val 275 280 285 Glu Val His Asn Ala Lys Thr Lys Pro Arg Glu Glu Gln Tyr Asn Ser 290 295 300 Thr Tyr Arg Val Val Ser Val Leu Thr Val Leu His Gln Asp Trp Leu 305 310 315 320 Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys Ala Leu Pro Ala 325 330 335 Pro Ile Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln Pro Arg Glu Pro 340 345 350 Gln Val Cys Thr Leu Pro Pro Ser Arg Asp Glu Leu Thr Lys Asn Gln 355 360 365 Val Ser Leu Ser Cys Ala Val Lys Gly Phe Tyr Pro Ser Asp Ile Ala 370 375 380 Val Glu Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn Tyr Lys Thr Thr 385 390 395 400 Pro Pro Val Leu Asp Ser Asp Gly Ser Phe Phe Leu Val Ser Lys Leu 405 410 415 Thr Val Asp Lys Ser Arg Trp Gln Gln Gly Asn Val Phe Ser Cys Ser 420 425 430 Val Met His Glu Ala Leu His Asn His Tyr Thr Gln Lys Ser Leu Ser 435 440 445 Leu Ser Pro Gly 450 <210> 86 <211> 213 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 86 Asp Ile Gln Met Thr Gln Ser Pro Ala Ser Leu Ser Val Ser Val Gly 1 5 10 15 Asp Thr Ile Thr Leu Thr Cys His Ala Ser Gln Asn Ile Asp Val Trp 20 25 30 Leu Ser Trp Phe Gln Gln Lys Pro Gly Asn Ile Pro Lys Leu Leu Ile 35 40 45 Tyr Lys Ala Ser Asn Leu His Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Ala His Ser Tyr Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Gly Gln Pro Lys Ala 100 105 110 Ala Pro Ser Val Thr Leu Phe Pro Pro Ser Ser Glu Glu Leu Gln Ala 115 120 125 Asn Lys Ala Thr Leu Val Cys Leu Ile Ser Asp Phe Tyr Pro Gly Ala 130 135 140 Val Thr Val Ala Trp Lys Ala Asp Ser Ser Pro Val Lys Ala Gly Val 145 150 155 160 Glu Thr Thr Thr Pro Ser Lys Gln Ser Asn Asn Lys Tyr Ala Ala Ser 165 170 175 Ser Tyr Leu Ser Leu Thr Pro Glu Gln Trp Lys Ser His Arg Ser Tyr 180 185 190 Ser Cys Gln Val Thr His Glu Gly Ser Thr Val Glu Lys Thr Val Ala 195 200 205 Pro Thr Glu Cys Ser 210 <210> 87 <211> 568 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 87 Glu Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala Pro Gly Gly 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Thr Asp Ser 20 25 30 Ser Ile Asn Trp Val Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Met Ile Trp Gly Asp Gly Arg Ile Asp Tyr Ala Asp Ala Leu Lys 50 55 60 Ser Arg Leu Ser Ile Ser Lys Asp Ser Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Glu Met Thr Ser Leu Arg Thr Asp Asp Thr Ala Thr Tyr Tyr Cys Ala 85 90 95 Arg Asp Gly Tyr Phe Pro Tyr Ala Met Asp Phe Trp Gly Gln Gly Thr 100 105 110 Ser Val Thr Val Ser Ser Glu Val Gln Leu Val Glu Ser Gly Gly Gly 115 120 125 Leu Val Gln Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly 130 135 140 Phe Thr Phe Asp Asp Tyr Ala Met His Trp Val Arg Gln Ala Pro Gly 145 150 155 160 Lys Gly Leu Glu Trp Val Ser Ala Ile Thr Trp Asn Ser Gly His Ile 165 170 175 Asp Tyr Ala Asp Ser Val Glu Gly Arg Phe Thr Ile Ser Arg Asp Asn 180 185 190 Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 195 200 205 Thr Ala Val Tyr Tyr Cys Ala Lys Val Ser Tyr Leu Ser Thr Ala Ser 210 215 220 Ser Leu Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Ala 225 230 235 240 Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala Pro Ser Ser Lys Ser 245 250 255 Thr Ser Gly Gly Thr Ala Ala Leu Gly Cys Leu Val Lys Asp Tyr Phe 260 265 270 Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly Ala Leu Thr Ser Gly 275 280 285 Val His Thr Phe Pro Ala Val Leu Gln Ser Ser Gly Leu Tyr Ser Leu 290 295 300 Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr Gln Thr Tyr 305 310 315 320 Ile Cys Asn Val Asn His Lys Pro Ser Asn Thr Lys Val Asp Lys Lys 325 330 335 Val Glu Pro Lys Ser Cys Asp Lys Thr His Thr Cys Pro Pro Cys Pro 340 345 350 Ala Pro Glu Leu Leu Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys 355 360 365 Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val 370 375 380 Val Val Asp Val Ser His Glu Asp Pro Glu Val Lys Phe Asn Trp Tyr 385 390 395 400 Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg Glu Glu 405 410 415 Gln Tyr Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val Leu His 420 425 430 Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys 435 440 445 Ala Leu Pro Ala Pro Ile Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln 450 455 460 Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Cys Arg Asp Glu Leu 465 470 475 480 Thr Lys Asn Gln Val Ser Leu Trp Cys Leu Val Lys Gly Phe Tyr Pro 485 490 495 Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn 500 505 510 Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe Phe Leu 515 520 525 Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg Trp Gln Gln Gly Asn Val 530 535 540 Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn Arg Phe Thr Gln 545 550 555 560 Lys Ser Leu Ser Leu Ser Pro Gly 565 <210> 88 <211> 344 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 88 Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp 1 5 10 15 Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Arg Asn Tyr Leu 20 25 30 Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr 35 40 45 Ala Ala Ser Thr Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly Ser 50 55 60 Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu 65 70 75 80 Asp Val Ala Thr Tyr Tyr Cys Gln Arg Tyr Asn Arg Ala Pro Tyr Thr 85 90 95 Phe Gly Gln Gly Thr Lys Val Glu Ile Lys Gly Gly Ser Gly Ser Ser 100 105 110 Gly Ser Gly Gly Asp Ile Val Leu Thr Gln Ser Pro Ala Ser Leu Ala 115 120 125 Val Ser Leu Gly Gln Arg Ala Thr Ile Ser Cys Arg Ala Ser Glu Ser 130 135 140 Val Asp Ser Tyr Gly Gln Ser Tyr Met His Trp Tyr Gln Gln Lys Ala 145 150 155 160 Gly Gln Pro Pro Lys Leu Leu Ile Tyr Leu Ala Ser Asn Leu Glu Ser 165 170 175 Gly Val Pro Ala Arg Phe Ser Gly Ser Gly Ser Arg Thr Asp Phe Thr 180 185 190 Leu Thr Ile Asp Pro Val Gln Ala Glu Asp Ala Ala Thr Tyr Tyr Cys 195 200 205 Gln Gln Asn Ala Glu Asp Ser Arg Thr Phe Gly Gly Gly Thr Lys Leu 210 215 220 Glu Ile Lys Gly Gly Ser Gly Ser Ser Gly Ser Gly Gly Arg Thr Val 225 230 235 240 Ala Ala Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys 245 250 255 Ser Gly Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg 260 265 270 Glu Ala Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn 275 280 285 Ser Gln Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser 290 295 300 Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys 305 310 315 320 Val Tyr Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr 325 330 335 Lys Ser Phe Asn Arg Gly Glu Cys 340 <210> 89 <211> 1356 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 89 caggtgcagc tgcagcagag cggccccgag ctggtgaagc ccggcgccag cgtgaagatc 60 agctgcaagg ccagcggcta cagcttcacc agctactgga ttcactggat caagcagcgc 120 cccggccagg gcctggagtg gatcggcatg atcgacccca gcgacggcga gacccgcctg 180 aaccagcgct tccagggccg cgccaccctg accgtggacg agagcaccag caccgcctac 240 atgcagctgc gcagccccac cagcgaggac agcgccgtgt actactgcac ccgcctgaag 300 gagtacggca actacgacag cttctacttc gacgtgtggg gcgccggcac cctggtgacc 360 gtgagcagcg ccagcaccaa gggccccagc gtgttccccc tggcccctag cagcaagagc 420 acatctggcg gcacagccgc cctgggctgc ctggtcaagg actacttccc cgagcccgtg 480 acagtgtcct ggaactctgg cgccctgacc agcggagtgc ataccttccc tgccgtgctg 540 cagtccagcg gcctgtacag cctgagcagc gtggtcacag tgcccagcag cagcctgggc 600 acccagacct acatctgcaa cgtgaaccac aagcccagca acaccaaggt ggacaagaag 660 gtggaaccca agagctgcga caagacccac acctgtcccc cctgccctgc ccctgaactg 720 ctgggcggac cctccgtgtt cctgttcccc ccaaagccca aggacaccct gatgatcagc 780 cggacccccg aagtgacctg cgtggtggtg gacgtgtccc acgaggaccc tgaagtgaag 840 ttcaattggt acgtggacgg cgtggaagtg cataacgcca agaccaagcc cagagaggaa 900 cagtacaaca gcacctaccg ggtggtgtcc gtgctgaccg tgctgcacca ggactggctg 960 aacggcaaag agtacaagtg caaggtgtcc aacaaggccc tgcctgcccc catcgagaaa 1020 accatcagca aggccaaggg ccagcctaga gagccccaag tctgcaccct gccccccagc 1080 agagatgagc tgaccaagaa ccaggtgtcc ctgagctgcg ccgtgaaggg cttctacccc 1140 agcgatatcg ccgtggaatg ggagagcaac ggccagcccg agaacaacta caagaccacc 1200 ccccctgtgc tggacagcga cggctcattc ttcctggtgt ccaagctgac agtggacaag 1260 agccggtggc agcagggcaa cgtgttcagc tgcagcgtga tgcacgaggc cctgcacaac 1320 cattacaccc agaagtccct gagcctgagc cccggc 1356 <210> 90 <211> 639 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 90 gacatccaga tgacccagag ccccgccagc ctgagcgtgt ccgtgggcga taccatcacc 60 ctgacctgcc acgccagcca gaacatcgac gtgtggctga gctggttcca gcagaagccc 120 ggcaacatcc ccaagctgct gatctacaag gccagcaacc tgcacaccgg cgtgcccagc 180 agattcagcg gctctggcag cggcaccggc tttaccctga ccatcagcag cctgcagccc 240 gaggatatcg ccacctacta ctgccagcag gcccacagct accccttcac cttcggcgga 300 ggcaccaagc tggaaatcaa gggacagccc aaggctgccc cctcggtcac cctgttcccc 360 ccaagctctg aggaactgca ggccaacaag gccaccctcg tgtgcctgat cagcgacttc 420 taccctggcg ccgtgaccgt ggcctggaag gccgatagct ctcccgtgaa ggccggcgtg 480 gaaaccacca cccccagcaa gcagagcaac aacaaatacg ccgccagcag ctacctgagc 540 ctgacccccg agcagtggaa gtcccaccgg tcctacagct gccaggtcac acacgagggc 600 agcaccgtgg aaaagaccgt ggcccccacc gagtgcagc 639 <210> 91 <211> 1704 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 91 gaggtgcagc tgaaagagtc cggccctgga ctggtggccc ctggcggcag cctgagcatc 60 acctgtaccg tgtccggctt cagcctgacc gacagcagca tcaactgggt ccgacagccc 120 cctggcaagg gcctggaatg gctgggcatg atctggggcg acggccggat cgactacgcc 180 gacgccctga agtcccggct gagcatcagc aaggacagca gcaagagcca ggtgttcctg 240 gaaatgacca gcctgcggac cgacgacacc gccacctact actgcgccag ggacggctac 300 ttcccctacg ccatggattt ctggggccag ggcaccagcg tgaccgtgtc ctccgaagtg 360 cagctggtgg aaagcggcgg aggcctggtg cagcccggca gaagcctgag actgagctgc 420 gccgccagcg gcttcacctt cgacgactac gccatgcact gggtccgcca ggctcccgga 480 aagggactcg agtgggtgtc cgccatcacc tggaacagcg gccacatcga ttacgccgat 540 agcgtggaag gccggttcac catcagccgg gacaacgcca agaacagcct gtacctgcag 600 atgaacagcc tgagagccga ggataccgcc gtgtactact gtgccaaggt gtcctacctg 660 agcaccgcca gcagcctgga ctactgggga cagggaaccc tggtcaccgt gtccagcgct 720 tccaccaagg gccccagcgt gttccctctg gcccctagca gcaagagcac atctggcgga 780 acagccgccc tgggctgcct ggtcaaggac tactttcccg agcccgtgac cgtgtcctgg 840 aactctggtg ccctgacaag cggagtgcat accttccctg ccgtgctgca gagcagcggc 900 ctgtactctc tgagcagcgt ggtcaccgtg ccaagcagca gcctgggcac ccagacctac 960 atctgcaacg tgaaccacaa gccctccaac accaaggtgg acaagaaggt ggaacccaag 1020 agctgcgaca agacccacac ctgtcctccc tgtcctgccc ctgaactgct gggcggaccc 1080 tccgtgttcc tgttccctcc aaagcccaag gataccctga tgatcagccg gacccctgaa 1140 gtgacctgcg tggtggtgga cgtgtcccac gaggatcccg aagtgaagtt caattggtac 1200 gtggacggcg tggaagtgca taacgccaag accaagccca gagaggaaca gtacaacagc 1260 acctaccggg tggtgtccgt gctgacagtg ctgcaccagg actggctgaa cggcaaagag 1320 tacaagtgca aggtgtccaa caaggccctg ccagccccta tcgagaaaac catcagcaag 1380 gccaagggcc agccccgcga gcctcaggtg tacacactgc ctccatgccg ggacgagctg 1440 accaagaacc aggtgtccct gtggtgcctc gtgaagggct tctacccctc cgatatcgcc 1500 gtggaatggg agagcaacgg ccagcccgag aacaactaca agaccacccc tcccgtgctg 1560 gacagcgacg gctcattctt cctgtacagc aagctgaccg tggacaagtc ccggtggcag 1620 cagggcaacg tgttcagctg ctctgtgatg cacgaggccc tgcacaaccg gttcacccag 1680 aagtccctga gcctgagccc tggc 1704 <210> 92 <211> 1035 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 92 gacatccaga tgacccagag ccccagcagc ctgagcgcca gcgtgggcga cagagtgacc 60 atcacctgtc gggccagcca gggcatccgg aactacctgg cctggtatca gcagaagccc 120 ggcaaggccc ccaagctgct gatctacgcc gccagcacac tgcagagcgg cgtgcccagc 180 agattcagcg gcagcggctc cggcaccgac ttcaccctga ccatcagcag cctgcagccc 240 gaggacgtgg ccacctacta ctgccagcgg tacaacagag ccccctacac cttcggccag 300 ggcaccaagg tggaaatcaa gggcggctct ggcagctccg gctctggcgg cgatatcgtg 360 ctgacccagt ctcccgccag cctggccgtg tctctgggcc agagagccac catcagctgc 420 agagccagcg agagcgtgga cagctacggc cagagctaca tgcattggta tcagcagaaa 480 gccggccagc ctcctaaact gctcatctac ctggccagca acctggaatc cggcgtgccc 540 gccaggtttt ccggcagcgg cagcagaacc gatttcacac tgacaatcga ccccgtgcag 600 gccgaggatg ccgccacata ttactgtcag cagaacgccg aggacagccg gaccttcggc 660 ggaggcacca agctcgagat taagggcgga agcggctcca gcggcagtgg cggacgtacg 720 gtggccgctc cttccgtgtt catcttccct ccctccgacg agcagctgaa gtccggcacc 780 gcctccgtgg tgtgtctgct gaacaacttc taccctcggg aggccaaggt gcagtggaag 840 gtggacaacg ccctgcagtc cggcaactcc caggagtccg tcaccgagca ggactccaag 900 gacagcacct actccctgtc ctccaccctg accctgtcca aggccgacta cgagaagcac 960 aaggtgtacg cctgtgaggt gacccaccag ggcctgtcca gccctgtgac caagtccttc 1020 aaccggggcg agtgc 1035 <210> 93 <211> 568 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 93 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Asp Asp Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Ala Ile Thr Trp Asn Ser Gly His Ile Asp Tyr Ala Asp Ser Val 50 55 60 Glu Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Val Ser Tyr Leu Ser Thr Ala Ser Ser Leu Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser Glu Val Gln Leu Lys Glu Ser 115 120 125 Gly Pro Gly Leu Val Ala Pro Gly Gly Ser Leu Ser Ile Thr Cys Thr 130 135 140 Val Ser Gly Phe Ser Leu Thr Asp Ser Ser Ile Asn Trp Val Arg Gln 145 150 155 160 Pro Pro Gly Lys Gly Leu Glu Trp Leu Gly Met Ile Trp Gly Asp Gly 165 170 175 Arg Ile Asp Tyr Ala Asp Ala Leu Lys Ser Arg Leu Ser Ile Ser Lys 180 185 190 Asp Ser Ser Lys Ser Gln Val Phe Leu Glu Met Thr Ser Leu Arg Thr 195 200 205 Asp Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Asp Gly Tyr Phe Pro Tyr 210 215 220 Ala Met Asp Phe Trp Gly Gln Gly Thr Ser Val Thr Val Ser Ser Ala 225 230 235 240 Ser Thr Lys Gly Pro Ser Val Phe Pro Leu Ala Pro Ser Ser Lys Ser 245 250 255 Thr Ser Gly Gly Thr Ala Ala Leu Gly Cys Leu Val Lys Asp Tyr Phe 260 265 270 Pro Glu Pro Val Thr Val Ser Trp Asn Ser Gly Ala Leu Thr Ser Gly 275 280 285 Val His Thr Phe Pro Ala Val Leu Gln Ser Ser Gly Leu Tyr Ser Leu 290 295 300 Ser Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr Gln Thr Tyr 305 310 315 320 Ile Cys Asn Val Asn His Lys Pro Ser Asn Thr Lys Val Asp Lys Lys 325 330 335 Val Glu Pro Lys Ser Cys Asp Lys Thr His Thr Cys Pro Pro Cys Pro 340 345 350 Ala Pro Glu Leu Leu Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys 355 360 365 Pro Lys Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val 370 375 380 Val Val Asp Val Ser His Glu Asp Pro Glu Val Lys Phe Asn Trp Tyr 385 390 395 400 Val Asp Gly Val Glu Val His Asn Ala Lys Thr Lys Pro Arg Glu Glu 405 410 415 Gln Tyr Asn Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val Leu His 420 425 430 Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys 435 440 445 Ala Leu Pro Ala Pro Ile Glu Lys Thr Ile Ser Lys Ala Lys Gly Gln 450 455 460 Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Cys Arg Asp Glu Leu 465 470 475 480 Thr Lys Asn Gln Val Ser Leu Trp Cys Leu Val Lys Gly Phe Tyr Pro 485 490 495 Ser Asp Ile Ala Val Glu Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn 500 505 510 Tyr Lys Thr Thr Pro Pro Val Leu Asp Ser Asp Gly Ser Phe Phe Leu 515 520 525 Tyr Ser Lys Leu Thr Val Asp Lys Ser Arg Trp Gln Gln Gly Asn Val 530 535 540 Phe Ser Cys Ser Val Met His Glu Ala Leu His Asn Arg Phe Thr Gln 545 550 555 560 Lys Ser Leu Ser Leu Ser Pro Gly 565 <210> 94 <211> 345 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 94 Asp Ile Val Leu Thr Gln Ser Pro Ala Ser Leu Ala Val Ser Leu Gly 1 5 10 15 Gln Arg Ala Thr Ile Ser Cys Arg Ala Ser Glu Ser Val Asp Ser Tyr 20 25 30 Gly Gln Ser Tyr Met His Trp Tyr Gln Gln Lys Ala Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Tyr Leu Ala Ser Asn Leu Glu Ser Gly Val Pro Ala 50 55 60 Arg Phe Ser Gly Ser Gly Ser Arg Thr Asp Phe Thr Leu Thr Ile Asp 65 70 75 80 Pro Val Gln Ala Glu Asp Ala Ala Thr Tyr Tyr Cys Gln Gln Asn Ala 85 90 95 Glu Asp Ser Arg Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Gly 100 105 110 Gly Ser Gly Ser Ser Gly Ser Gly Gly Asp Ile Gln Met Thr Gln Ser 115 120 125 Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr Cys 130 135 140 Arg Ala Ser Gln Gly Ile Arg Asn Tyr Leu Ala Trp Tyr Gln Gln Lys 145 150 155 160 Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Thr Leu Gln 165 170 175 Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe 180 185 190 Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Val Ala Thr Tyr Tyr 195 200 205 Cys Gln Arg Tyr Asn Arg Ala Pro Tyr Thr Phe Gly Gln Gly Thr Lys 210 215 220 Val Glu Ile Lys Gly Gly Ser Gly Ser Ser Gly Ser Gly Gly Arg Thr 225 230 235 240 Val Ala Ala Pro Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu 245 250 255 Lys Ser Gly Thr Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro 260 265 270 Arg Glu Ala Lys Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly 275 280 285 Asn Ser Gln Glu Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr 290 295 300 Ser Leu Ser Ser Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His 305 310 315 320 Lys Val Tyr Ala Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val 325 330 335 Thr Lys Ser Phe Asn Arg Gly Glu Cys 340 345 <210> 95 <211> 1704 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 95 gaggtgcagc tggtggaaag cggcggagga ctggtgcagc ccggcagaag cctgagactg 60 agctgcgccg ccagcggctt caccttcgac gactacgcca tgcactgggt ccgacaggcc 120 cctggcaagg gcctggaatg ggtgtccgcc atcacctgga acagcggcca catcgactac 180 gccgacagcg tggaaggccg gttcaccatc agccgggaca acgccaagaa cagcctgtac 240 ctgcagatga acagcctgcg ggccgaggac accgccgtgt actactgcgc caaggtgtcc 300 tacctgagca ccgccagcag cctggactac tggggccagg gcaccctggt caccgtgtcc 360 tccgaagtgc agctgaaaga gtccggccct ggcctggtgg cccctggcgg cagcctgagc 420 atcacctgta ccgtgtccgg cttcagcctg accgacagca gcatcaactg ggtccgccag 480 cctcccggaa agggactcga gtggctgggc atgatctggg gcgacggccg gatcgattac 540 gccgatgccc tgaagtcccg gctgagcatc agcaaggaca gcagcaagag ccaggtgttc 600 ctggaaatga ccagcctgag aaccgacgac accgccacct actactgtgc ccgggacggc 660 tacttcccct acgccatgga tttctgggga cagggaacca gcgtgaccgt gtccagcgct 720 tccaccaagg gccccagcgt gttccctctg gcccctagca gcaagagcac atctggcgga 780 acagccgccc tgggctgcct ggtcaaggac tactttcccg agcccgtgac cgtgtcctgg 840 aactctggtg ccctgacaag cggagtgcat accttccctg ccgtgctgca gagcagcggc 900 ctgtactctc tgagcagcgt ggtcaccgtg ccaagcagca gcctgggcac ccagacctac 960 atctgcaacg tgaaccacaa gccctccaac accaaggtgg acaagaaggt ggaacccaag 1020 agctgcgaca agacccacac ctgtcctccc tgtcctgccc ctgaactgct gggcggaccc 1080 tccgtgttcc tgttccctcc aaagcccaag gataccctga tgatcagccg gacccctgaa 1140 gtgacctgcg tggtggtgga cgtgtcccac gaggatcccg aagtgaagtt caattggtac 1200 gtggacggcg tggaagtgca taacgccaag accaagccca gagaggaaca gtacaacagc 1260 acctaccggg tggtgtccgt gctgacagtg ctgcaccagg actggctgaa cggcaaagag 1320 tacaagtgca aggtgtccaa caaggccctg ccagccccta tcgagaaaac catcagcaag 1380 gccaagggcc agccccgcga gcctcaggtg tacacactgc ctccatgccg ggacgagctg 1440 accaagaacc aggtgtccct gtggtgcctc gtgaagggct tctacccctc cgatatcgcc 1500 gtggaatggg agagcaacgg ccagcccgag aacaactaca agaccacccc tcccgtgctg 1560 gacagcgacg gctcattctt cctgtacagc aagctgaccg tggacaagtc ccggtggcag 1620 cagggcaacg tgttcagctg ctctgtgatg cacgaggccc tgcacaaccg gttcacccag 1680 aagtccctga gcctgagccc tggc 1704 <210> 96 <211> 1035 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 96 gacatcgtgc tgacccagag ccctgccagc ctggccgtgt ctctgggcca gagagccacc 60 atcagctgcc gggccagcga gagcgtggac agctacggcc agagctacat gcactggtat 120 cagcagaagg ccggccagcc ccccaagctg ctgatctacc tggccagcaa cctggaaagc 180 ggcgtgcccg ccagattcag cggcagcggc agcagaaccg acttcaccct gaccatcgac 240 cccgtgcagg ccgaggacgc cgccacctac tactgccagc agaacgccga ggacagccgg 300 accttcggcg gaggcaccaa gctggaaatc aagggcggct ccggcagcag cggctctggc 360 ggcgatatcc agatgaccca gtcccccagc agcctgagcg ccagcgtggg cgacagagtg 420 accatcacct gtagagccag ccagggcatc cggaactacc tggcttggta tcagcagaaa 480 cccggaaagg cccctaaact gctcatctac gccgccagca ccctgcagtc cggcgtgcca 540 agcagattct ccggctctgg cagcggcacc gatttcacac tgacaatcag cagcctgcag 600 cccgaggatg tggccaccta ttattgccag agatacaaca gagcccccta caccttcggc 660 cagggcacca aggtcgagat taagggcgga agcggcagct ccggctccgg cggacgtacg 720 gtggccgctc cttccgtgtt catcttccct ccctccgacg agcagctgaa gtccggcacc 780 gcctccgtgg tgtgtctgct gaacaacttc taccctcggg aggccaaggt gcagtggaag 840 gtggacaacg ccctgcagtc cggcaactcc caggagtccg tcaccgagca ggactccaag 900 gacagcacct actccctgtc ctccaccctg accctgtcca aggccgacta cgagaagcac 960 aaggtgtacg cctgtgaggt gacccaccag ggcctgtcca gccctgtgac caagtccttc 1020 aaccggggcg agtgc 1035 <210> 97 <211> 1710 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 97 gaggtgcagc tgaaagagtc cggccctgga ctggtggccc ctggcggcag cctgagcatc 60 acctgtaccg tgtccggctt cagcctgacc gacagcagca tcaactgggt ccgacagccc 120 cctggcaagg gcctggaatg gctgggcatg atctggggcg acggccggat cgactacgcc 180 gacgccctga agtcccggct gagcatcagc aaggacagca gcaagagcca ggtgttcctg 240 gaaatgacca gcctgcggac cgacgacacc gccacctact actgcgccag ggacggctac 300 ttcccctacg ccatggattt ctggggccag ggcaccagcg tgaccgtgtc cagtcaggtc 360 cagctgcagc agagcggccc tgagctggtc aagcctggcg ccagcgtgaa gatcagctgc 420 aaggccagcg gctacagctt caccagctac tggatccact ggatcaagca gcggcctggc 480 cagggcctcg agtggatcgg aatgatcgac cccagcgacg gcgagacacg gctgaaccag 540 agattccagg gcagagccac cctgaccgtg gacgagagca ccagcaccgc ctacatgcag 600 ctgcggagcc ccaccagcga ggacagcgcc gtgtactact gcacccggct gaaagaatac 660 ggcaactacg acagcttcta cttcgacgtg tggggagccg gcaccctggt caccgtgtct 720 agcgcttcca ccaagggccc cagcgtgttc cctctggccc ctagcagcaa gagcacatct 780 ggcggaacag ccgccctggg ctgcctggtc aaggactact ttcccgagcc cgtgaccgtg 840 tcctggaact ctggtgccct gacaagcgga gtgcatacct tccctgccgt gctgcagagc 900 agcggcctgt actctctgag cagcgtggtc accgtgccaa gcagcagcct gggcacccag 960 acctacatct gcaacgtgaa ccacaagccc tccaacacca aggtggacaa gaaggtggaa 1020 cccaagagct gcgacaagac ccacacctgt cctccctgtc ctgcccctga actgctgggc 1080 ggaccctccg tgttcctgtt ccctccaaag cccaaggata ccctgatgat cagccggacc 1140 cctgaagtga cctgcgtggt ggtggacgtg tcccacgagg atcccgaagt gaagttcaat 1200 tggtacgtgg acggcgtgga agtgcataac gccaagacca agcccagaga ggaacagtac 1260 aacagcacct accgggtggt gtccgtgctg acagtgctgc accaggactg gctgaacggc 1320 aaagagtaca agtgcaaggt gtccaacaag gccctgccag cccctatcga gaaaaccatc 1380 agcaaggcca agggccagcc ccgcgagcct caggtgtaca cactgcctcc atgccgggac 1440 gagctgacca agaaccaggt gtccctgtgg tgcctcgtga agggcttcta cccctccgat 1500 atcgccgtgg aatgggagag caacggccag cccgagaaca actacaagac cacccctccc 1560 gtgctggaca gcgacggctc attcttcctg tacagcaagc tgaccgtgga caagtcccgg 1620 tggcagcagg gcaacgtgtt cagctgctct gtgatgcacg aggccctgca caaccggttc 1680 acccagaagt ccctgagcct gagccctggc 1710 <210> 98 <211> 4 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 98 Gly Gly Gly Gly 1 <210> 99 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 99 Gly Gly Gly Gly Gly 1 5 <210> 100 <211> 6 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 100 Gly Gly Gly Gly Gly Gly 1 5 <210> 101 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 101 Gly Gly Gly Gly Gly Gly Gly 1 5 <210> 102 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 102 Gly Gly Gly Gly Gly Gly Gly Gly 1 5 <210> 103 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 103 Gly Gly Gly Gly Ser 1 5 <210> 104 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 104 Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 1 5 10 <210> 105 <211> 15 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 105 Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 1 5 10 15 <210> 106 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 106 Thr Lys Gly Pro Ser 1 5 <210> 107 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 107 Thr Val Ala Ala Pro 1 5 <210> 108 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 108 Gln Pro Lys Ala Ala 1 5 <210> 109 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 109 Gln Arg Ile Glu Gly 1 5 <210> 110 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 110 Ala Ser Thr Lys Gly Pro Ser 1 5 <210> 111 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 111 Arg Thr Val Ala Ala Pro Ser 1 5 <210> 112 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 112 Gly Gln Pro Lys Ala Ala Pro 1 5 <210> 113 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 113 His Ile Asp Ser Pro Asn Lys 1 5 <210> 114 <211> 448 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 114 Gln Val Gln Leu Gln Gln Pro Gly Ala Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Met Ser Cys Lys Ala Ser Gly Tyr Thr Phe Thr Ser Tyr 20 25 30 Asn Met His Trp Val Lys Gln Thr Pro Gly Arg Gly Leu Glu Trp Ile 35 40 45 Gly Ala Ile Tyr Pro Gly Asn Gly Asp Thr Ser Tyr Asn Gln Lys Phe 50 55 60 Lys Gly Lys Ala Thr Leu Thr Ala Asp Lys Ser Ser Ser Thr Ala Tyr 65 70 75 80 Met Gln Leu Ser Ser Leu Thr Ser Glu Asp Ser Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Ser Thr Tyr Tyr Gly Gly Asp Trp Tyr Phe Asn Val Trp Gly 100 105 110 Ala Gly Thr Thr Val Thr Val Ser Ala Ala Ser Thr Lys Gly Pro Ser 115 120 125 Val Phe Pro Leu Ala Pro Cys Ser Arg Ser Thr Ser Glu Ser Thr Ala 130 135 140 Ala Leu Gly Cys Leu Val Lys Asp Tyr Phe Pro Glu Pro Val Thr Val 145 150 155 160 Ser Trp Asn Ser Gly Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala 165 170 175 Val Leu Gln Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val 180 185 190 Pro Ser Ser Ser Leu Gly Thr Lys Thr Tyr Thr Cys Asn Val Asp His 195 200 205 Lys Pro Ser Asn Thr Lys Val Asp Lys Arg Val Glu Ser Lys Tyr Gly 210 215 220 Pro Pro Cys Pro Pro Cys Pro Ala Pro Glu Phe Leu Gly Gly Pro Ser 225 230 235 240 Val Phe Leu Phe Pro Pro Lys Pro Lys Asp Thr Leu Met Ile Ser Arg 245 250 255 Thr Pro Glu Val Thr Cys Val Val Val Asp Val Ser Gln Glu Asp Pro 260 265 270 Glu Val Gln Phe Asn Trp Tyr Val Asp Gly Val Glu Val His Asn Ala 275 280 285 Lys Thr Lys Pro Arg Glu Glu Gln Phe Asn Ser Thr Tyr Arg Val Val 290 295 300 Ser Val Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly Lys Glu Tyr 305 310 315 320 Lys Cys Lys Val Ser Asn Lys Gly Leu Pro Ser Ser Ile Glu Lys Thr 325 330 335 Ile Ser Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln Val Tyr Thr Leu 340 345 350 Pro Pro Cys Gln Glu Glu Met Thr Lys Asn Gln Val Ser Leu Trp Cys 355 360 365 Leu Val Lys Gly Phe Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu Ser 370 375 380 Asn Gly Gln Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu Asp 385 390 395 400 Ser Asp Gly Ser Phe Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys Ser 405 410 415 Arg Trp Gln Glu Gly Asn Val Phe Ser Cys Ser Val Met His Glu Ala 420 425 430 Leu His Asn His Tyr Thr Gln Lys Ser Leu Ser Leu Ser Leu Gly Lys 435 440 445 <210> 115 <211> 213 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 115 Gln Ile Val Leu Ser Gln Ser Pro Ala Ile Leu Ser Ala Ser Pro Gly 1 5 10 15 Glu Lys Val Thr Met Thr Cys Arg Ala Ser Ser Ser Val Ser Tyr Ile 20 25 30 His Trp Phe Gln Gln Lys Pro Gly Ser Ser Pro Lys Pro Trp Ile Tyr 35 40 45 Ala Thr Ser Asn Leu Ala Ser Gly Val Pro Val Arg Phe Ser Gly Ser 50 55 60 Gly Ser Gly Thr Ser Tyr Ser Leu Thr Ile Ser Arg Val Glu Ala Glu 65 70 75 80 Asp Ala Ala Thr Tyr Tyr Cys Gln Gln Trp Thr Ser Asn Pro Pro Thr 85 90 95 Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys Arg Thr Val Ala Ala Pro 100 105 110 Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly Thr 115 120 125 Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu Ala Lys 130 135 140 Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly Asn Ser Gln Glu 145 150 155 160 Ser Val Thr Glu Gln Asp Ser Lys Asp Ser Thr Tyr Ser Leu Ser Ser 165 170 175 Thr Leu Thr Leu Ser Lys Ala Asp Tyr Glu Lys His Lys Val Tyr Ala 180 185 190 Cys Glu Val Thr His Gln Gly Leu Ser Ser Pro Val Thr Lys Ser Phe 195 200 205 Asn Arg Gly Glu Cys 210 <210> 116 <211> 1344 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 116 caggtgcagc tgcagcagcc tggcgccgaa ctcgtgaaac ctggcgcctc cgtgaagatg 60 agctgcaagg ccagcggcta caccttcacc agctacaaca tgcactgggt caagcagacc 120 cccggcagag gcctggaatg gatcggcgcc atctaccccg gcaacggcga cacctcctac 180 aaccagaagt tcaagggcaa ggccaccctg accgccgaca agagcagcag cacagcctac 240 atgcagctgt ccagcctgac cagcgaggac agcgccgtgt actactgcgc cagaagcacc 300 tactacggcg gcgactggta cttcaacgtg tggggagccg gcaccaccgt gacagtgtct 360 gctgcttcga ccaagggccc atcggtgttc cctctggccc cttgcagcag aagcaccagc 420 gaatctacag ccgccctggg ctgcctcgtg aaggactact ttcccgagcc cgtgaccgtg 480 tcctggaact ctggcgctct gacaagcggc gtgcacacct ttccagccgt gctccagagc 540 agcggcctgt actctctgag cagcgtcgtg acagtgccca gcagcagcct gggcaccaag 600 acctacacct gtaacgtgga ccacaagccc agcaacacca aggtggacaa gcgggtggaa 660 tctaagtacg gccctccctg ccctccttgc ccagcccctg aatttctggg cggaccctcc 720 gtgttcctgt tccccccaaa gcccaaggac accctgatga tcagccggac ccccgaagtg 780 acctgcgtgg tggtggatgt gtcccaggaa gatcccgagg tgcagttcaa ttggtacgtg 840 gacggcgtgg aagtgcacaa cgccaagacc aagcccagag aggaacagtt caacagcacc 900 taccgggtgg tgtccgtgct gaccgtgctg caccaggact ggctgaacgg caaagagtac 960 aagtgcaagg tgtccaacaa gggcctgccc agctccatcg agaaaaccat cagcaaggcc 1020 aagggccagc cccgcgagcc tcaagtgtat accctgcccc cttgccagga agagatgacc 1080 aagaaccagg tgtccctgtg gtgtctcgtg aaaggcttct accccagcga cattgccgtg 1140 gaatgggaga gcaacggcca gcccgagaac aactacaaga ccaccccccc tgtgctggac 1200 agcgacggct cattcttcct gtactccaag ctgaccgtgg acaagagccg gtggcaggaa 1260 ggcaacgtgt tcagctgctc cgtgatgcac gaggccctgc acaaccacta cacccagaag 1320 tccctgtctc tgtccctggg caag 1344 <210> 117 <211> 639 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 117 cagatcgtgc tgagccagag ccctgccatc ctgagcgctt ccccaggcga gaaagtgacc 60 atgacctgca gagccagcag cagcgtgtcc tacatccact ggttccagca gaagcccggc 120 agcagcccca agccttggat ctacgccacc agcaatctgg ccagcggagt gcctgtgcgg 180 tttagcggct ctggcagcgg cacaagctac agcctgacca tcagccgggt ggaagccgaa 240 gatgccgcca cctactactg ccagcagtgg accagcaacc cccccacatt tggcggaggc 300 accaagctgg aaatcaagcg tacggtggcc gctcccagcg tgttcatctt cccacctagc 360 gacgagcagc tgaagtccgg cacagcctct gtcgtgtgcc tgctgaacaa cttctacccc 420 cgcgaggcca aagtgcagtg gaaggtggac aacgccctgc agagcggcaa cagccaggaa 480 agcgtgaccg agcaggacag caaggactcc acctacagcc tgagcagcac cctgacactg 540 agcaaggccg actacgagaa gcacaaggtg tacgcctgcg aagtgaccca ccagggcctg 600 tctagccccg tgaccaagag cttcaaccgg ggcgagtgt 639 <210> 118 <211> 1713 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 118 caggtgcagc tgcaggaatc tggccctggc ctcgtgaagc ctagccagac cctgagcctg 60 acctgtaccg tgtccggctt cagcctgagc gactacggcg tgcactgggt gcgccagcca 120 cctggaaaag gcctggaatg gctgggcgtg atctgggctg gcggaggcac caactacaac 180 cccagcctga agtccagaaa gaccatcagc aaggacacca gcaagaacca ggtgtccctg 240 aagctgagca gcgtgacagc cgccgatacc gccgtgtact actgcgccag agacaagggc 300 tacagctact actacagcat ggactactgg ggccagggca ccaccgtgac cgtgtcatcc 360 tctcaggtgc agctggtgga atctggcggc ggagtggtgc agcctggcag aagcctgaga 420 ctgagctgtg ccgccagcgg cttcaccttc accaaggcct ggatgcactg ggtgcgccag 480 gcccctggaa agcagctgga atgggtggcc cagatcaagg acaagagcaa cagctacgcc 540 acctactacg ccgacagcgt gaagggccgg ttcaccatca gccgggacga cagcaagaac 600 accctgtacc tgcagatgaa cagcctgcgg gccgaggaca ccgccgtgta ctactgtcgg 660 ggcgtgtact atgccctgag ccccttcgat tactggggcc agggaaccct cgtgaccgtg 720 tctagtcgga ccgcttcgac caagggccca tcggtgttcc ctctggcccc ttgcagcaga 780 agcaccagcg aatctacagc cgccctgggc tgcctcgtga aggactactt tcccgagccc 840 gtgaccgtgt cctggaactc tggcgctctg acaagcggcg tgcacacctt tccagccgtg 900 ctccagagca gcggcctgta ctctctgagc agcgtcgtga cagtgcccag cagcagcctg 960 ggcaccaaga cctacacctg taacgtggac cacaagccca gcaacaccaa ggtggacaag 1020 cgggtggaat ctaagtacgg ccctccctgc cctccttgcc cagcccctga atttctgggc 1080 ggaccctccg tgttcctgtt ccccccaaag cccaaggaca ccctgatgat cagccggacc 1140 cccgaagtga cctgcgtggt ggtggatgtg tcccaggaag atcccgaggt gcagttcaat 1200 tggtacgtgg acggcgtgga agtgcacaac gccaagacca agcccagaga ggaacagttc 1260 aacagcacct accgggtggt gtccgtgctg accgtgctgc accaggactg gctgaacggc 1320 aaagagtaca agtgcaaggt gtccaacaag ggcctgccca gctccatcga gaaaaccatc 1380 agcaaggcca agggccagcc ccgcgagcct caagtgtgta ccctgccccc tagccaggaa 1440 gagatgacca agaaccaggt gtccctgagc tgtgccgtga aaggcttcta ccccagcgac 1500 attgccgtgg aatgggagag caacggccag cccgagaaca actacaagac caccccccct 1560 gtgctggaca gcgacggctc attcttcctg gtgtccaagc tgaccgtgga caagagccgg 1620 tggcaggaag gcaacgtgtt cagctgctcc gtgatgcacg aggccctgca caaccactac 1680 acccagaagt ccctgtctct gtccctgggc aag 1713 <210> 119 <211> 1026 <212> ADN <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 119 gacatcgtga tgacccagac ccccctgagc ctgagcgtga cacctggaca gcctgccagc 60 atcagctgca agagcagcca gagcctggtg cacaacaacg ccaacaccta cctgagctgg 120 tatctgcaga agcccggcca gagcccccag tccctgatct acaaggtgtc caacagattc 180 agcggcgtgc ccgacagatt ctccggcagc ggctctggca ccgacttcac cctgaagatc 240 agccgggtgg aagccgagga cgtgggcgtg tactattgtg gccagggcac ccagtacccc 300 ttcacctttg gcagcggcac caaggtggaa atcaagggcc agcccaaggc cgcccccgac 360 atcgtgctga cacagagccc tgctagcctg gccgtgtctc ctggacagag ggccaccatc 420 acctgtagag ccagcgagag cgtggaatat tacgtgacca gcctgatgca gtggtatcag 480 cagaagcccg gccagccccc caagctgctg attttcgccg ccagcaacgt ggaaagcggc 540 gtgccagcca gattttccgg cagcggctct ggcaccgact tcaccctgac catcaacccc 600 gtggaagcca acgacgtggc caactactac tgccagcaga gccggaaggt gccctacacc 660 tttggccagg gcaccaagct ggaaatcaag accaagggcc ccagccgtac ggtggccgct 720 cccagcgtgt tcatcttccc acctagcgac gagcagctga agtccggcac agcctctgtc 780 gtgtgcctgc tgaacaactt ctacccccgc gaggccaaag tgcagtggaa ggtggacaac 840 gccctgcaga gcggcaacag ccaggaaagc gtgaccgagc aggacagcaa ggactccacc 900 tacagcctga gcagcaccct gacactgagc aaggccgact acgagaagca caaggtgtac 960 gcctgcgaag tgacccacca gggcctgtct agccccgtga ccaagagctt caaccggggc 1020 gagtgt 1026 <210> 120 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 120 Gly Tyr Thr Phe Thr Ser Tyr Asn 1 5 <210> 121 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 121 Ile Tyr Pro Gly Asn Gly Asp Thr 1 5 <210> 122 <211> 14 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 122 Ala Arg Ser Thr Tyr Tyr Gly Gly Asp Trp Tyr Phe Asn Val 1 5 10 <210> 123 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 123 Ser Ser Val Ser Tyr 1 5 <210> 124 <211> 3 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 124 Ala Thr Ser 1 <210> 125 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 125 Gln Gln Trp Thr Ser Asn Pro 1 5 <210> 126 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 126 Gly Tyr Ile Phe Thr Asn Tyr Asn Ile His 1 5 10 <210> 127 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 127 Ala Ile Tyr Pro Gly Asn Gly Asp Ala Pro 1 5 10 <210> 128 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 128 Ala Asn Trp Asp Val Ala Phe Ala Tyr 1 5 <210> 129 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 129 Gly Phe Thr Phe Asp Asp Tyr Ala Met His 1 5 10 <210> 130 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 130 Ala Ile Thr Trp Asn Ser Gly His Ile Asp 1 5 10 <210> 131 <211> 12 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 131 Val Ser Tyr Leu Ser Thr Ala Ser Ser Leu Asp Tyr 1 5 10 <210> 132 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 132 Gly Tyr Ser Phe Thr Ser Tyr Trp Ile His 1 5 10 <210> 133 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 133 Met Ile Asp Pro Ser Asp Gly Glu Thr 1 5 <210> 134 <211> 14 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 134 Leu Lys Glu Tyr Gly Asn Tyr Asp Ser Phe Tyr Phe Asp Val 1 5 10 <210> 135 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 135 Gly Phe Ser Leu Thr Asp Ser Ser Ile Asn 1 5 10 <210> 136 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 136 Met Ile Trp Gly Asp Gly Arg Ile Asp 1 5 <210> 137 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 137 Asp Gly Tyr Phe Pro Tyr Ala Met Asp Phe 1 5 10 <210> 138 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 138 Lys Ala Ser Gln Asp Ile Asp Arg Tyr Met Ala 1 5 10 <210> 139 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 139 Asp Thr Ser Thr Leu Gln Ser 1 5 <210> 140 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 140 Leu Gln Tyr Asp Asn Leu Trp Thr 1 5 <210> 141 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 141 Arg Ala Ser Gln Gly Ile Arg Asn Tyr Leu Ala 1 5 10 <210> 142 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 142 Gln Arg Tyr Asn Arg Ala Pro Tyr Thr 1 5 <210> 143 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 143 His Ala Ser Gln Asn Ile Asp Val Trp Leu Ser 1 5 10 <210> 144 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 144 Gln Gln Ala His Ser Tyr Pro Phe Thr 1 5 <210> 145 <211> 15 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 145 Arg Ala Ser Glu Ser Val Asp Ser Tyr Gly Gln Ser Tyr Met His 1 5 10 15 <210> 146 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 146 Leu Ala Ser Asn Leu Glu Ser 1 5 <210> 147 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 147 Gln Gln Asn Ala Glu Asp Ser Arg Thr 1 5 <210> 148 <211> 10 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 148 Gly Gly Ser Gly Ser Ser Gly Ser Gly Gly 1 5 10 <210> 149 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 149 Gln Ser Leu Val His Asn Asn Gly Asn Thr Tyr 1 5 10 <210> 150 <211> 120 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 150 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Asn Ile Lys Asp Thr 20 25 30 Tyr Ile His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Arg Ile Tyr Pro Thr Asn Gly Tyr Thr Arg Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Ala Asp Thr Ser Lys Asn Thr Ala Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ser Arg Trp Gly Gly Asp Gly Phe Tyr Ala Met Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 151 <211> 107 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 151 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Asp Val Asn Thr Ala 20 25 30 Val Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Ser Ala Ser Phe Leu Tyr Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Arg Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln His Tyr Thr Thr Pro Pro 85 90 95 Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 <210> 152 <211> 121 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 152 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Thr Lys Ala 20 25 30 Trp Met His Trp Val Arg Gln Ala Pro Gly Lys Gln Leu Glu Trp Val 35 40 45 Ala Gln Ile Lys Asp Lys Ser Asn Ser Tyr Ala Thr Tyr Tyr Ala Asp 50 55 60 Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr 65 70 75 80 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 85 90 95 Tyr Cys Arg Gly Val Tyr Tyr Ala Leu Ser Pro Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 153 <211> 112 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 153 Asp Ile Val Met Thr Gln Thr Pro Leu Ser Leu Ser Val Thr Pro Gly 1 5 10 15 Gln Pro Ala Ser Ile Ser Cys Lys Ser Ser Gln Ser Leu Val His Asn 20 25 30 Asn Ala Asn Thr Tyr Leu Ser Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Gln Ser Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Gly Gln Gly 85 90 95 Thr Gln Tyr Pro Phe Thr Phe Gly Ser Gly Thr Lys Val Glu Ile Lys 100 105 110 <210> 154 <211> 121 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 154 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Thr Lys Ala 20 25 30 Trp Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Gln Ile Lys Asp Lys Ser Asn Ser Tyr Ala Thr Tyr Tyr Ala Asp 50 55 60 Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr 65 70 75 80 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 85 90 95 Tyr Cys Arg Gly Val Tyr Tyr Ala Leu Ser Pro Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 155 <211> 112 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 155 Asp Ile Val Met Thr Gln Thr Pro Leu Ser Leu Ser Val Thr Pro Gly 1 5 10 15 Gln Pro Ala Ser Ile Ser Cys Lys Ser Ser Gln Ser Leu Val His Asn 20 25 30 Asn Gly Asn Thr Tyr Leu Ser Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Gly Gln Gly 85 90 95 Thr Gln Tyr Pro Phe Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 100 105 110 <210> 156 <211> 124 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 156 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Ala Phe Ser Ser Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Gln Ile Trp Pro Gly Asp Gly Asp Thr Asn Tyr Asn Gln Lys Phe 50 55 60 Lys Gly Arg Ala Thr Leu Thr Ala Asp Glu Ser Thr Ser Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Arg Glu Thr Thr Thr Val Gly Arg Tyr Tyr Tyr Ala Met Asp 100 105 110 Tyr Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 <210> 157 <211> 111 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 157 Asp Leu Val Leu Thr Gln Ser Pro Ala Ser Leu Ala Val Ser Pro Gly 1 5 10 15 Gln Arg Ala Thr Ile Thr Cys Lys Ala Ser Gln Ser Val Asp Tyr Asp 20 25 30 Gly Asp Ser Tyr Leu Asn Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Tyr Asp Ala Ser Asn Leu Val Ser Gly Val Pro Ala 50 55 60 Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Asn 65 70 75 80 Pro Val Glu Ala Asn Asp Thr Ala Asn Tyr Tyr Cys Gln Gln Ser Thr 85 90 95 Glu Asp Pro Trp Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 158 <211> 121 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 158 Gln Val Gln Leu Gln Gln Pro Gly Ala Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Met Ser Cys Lys Ala Ser Gly Tyr Thr Phe Thr Ser Tyr 20 25 30 Asn Met His Trp Val Lys Gln Thr Pro Gly Arg Gly Leu Glu Trp Ile 35 40 45 Gly Ala Ile Tyr Pro Gly Asn Gly Asp Thr Ser Tyr Asn Gln Lys Phe 50 55 60 Lys Gly Lys Ala Thr Leu Thr Ala Asp Lys Ser Ser Ser Thr Ala Tyr 65 70 75 80 Met Gln Leu Ser Ser Leu Thr Ser Glu Asp Ser Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Ser Thr Tyr Tyr Gly Gly Asp Trp Tyr Phe Asn Val Trp Gly 100 105 110 Ala Gly Thr Thr Val Thr Val Ser Ala 115 120 <210> 159 <211> 106 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 159 Gln Ile Val Leu Ser Gln Ser Pro Ala Ile Leu Ser Ala Ser Pro Gly 1 5 10 15 Glu Lys Val Thr Met Thr Cys Arg Ala Ser Ser Ser Val Ser Tyr Ile 20 25 30 His Trp Phe Gln Gln Lys Pro Gly Ser Ser Pro Lys Pro Trp Ile Tyr 35 40 45 Ala Thr Ser Asn Leu Ala Ser Gly Val Pro Val Arg Phe Ser Gly Ser 50 55 60 Gly Ser Gly Thr Ser Tyr Ser Leu Thr Ile Ser Arg Val Glu Ala Glu 65 70 75 80 Asp Ala Ala Thr Tyr Tyr Cys Gln Gln Trp Thr Ser Asn Pro Pro Thr 85 90 95 Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 160 <211> 120 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 160 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Thr Phe Thr Ser Tyr 20 25 30 Tyr Ile His Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Ser Ile Tyr Pro Gly Asn Val Asn Thr Asn Tyr Ala Gln Lys Phe 50 55 60 Gln Gly Arg Ala Thr Leu Thr Val Asp Thr Ser Ile Ser Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Arg Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Ser His Tyr Gly Leu Asp Trp Asn Phe Asp Val Trp Gly Lys 100 105 110 Gly Thr Thr Val Thr Val Ser Ser 115 120 <210> 161 <211> 107 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 161 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Gln Ala Ser Gln Asn Ile Tyr Val Trp 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Lys Ala Ser Asn Leu His Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Gly Gln Thr Tyr Pro Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 162 <211> 120 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 162 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Gln 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Phe Ser Leu Ser Asp Tyr 20 25 30 Gly Val His Trp Val Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Val Ile Trp Ala Gly Gly Gly Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Lys Thr Ile Ser Lys Asp Thr Ser Lys Asn Gln Val Ser Leu 65 70 75 80 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 85 90 95 Arg Asp Lys Gly Tyr Ser Tyr Tyr Tyr Ser Met Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Thr Val Thr Val Ser Ser 115 120 <210> 163 <211> 111 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 163 Asp Ile Val Leu Thr Gln Ser Pro Ala Ser Leu Ala Val Ser Pro Gly 1 5 10 15 Gln Arg Ala Thr Ile Thr Cys Arg Ala Ser Glu Ser Val Glu Tyr Tyr 20 25 30 Val Thr Ser Leu Met Gln Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Phe Ala Ala Ser Asn Val Glu Ser Gly Val Pro Ala 50 55 60 Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Asn 65 70 75 80 Pro Val Glu Ala Asn Asp Val Ala Asn Tyr Tyr Cys Gln Gln Ser Arg 85 90 95 Lys Val Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 164 <211> 120 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 164 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Ala Lys Pro Gly Thr 1 5 10 15 Ser Val Lys Leu Ser Cys Lys Ala Ser Gly Tyr Thr Phe Thr Asp Tyr 20 25 30 Trp Met Gln Trp Val Lys Gln Arg Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Thr Ile Tyr Pro Gly Asp Gly Asp Thr Gly Tyr Ala Gln Lys Phe 50 55 60 Gln Gly Lys Ala Thr Leu Thr Ala Asp Lys Ser Ser Lys Thr Val Tyr 65 70 75 80 Met His Leu Ser Ser Leu Ala Ser Glu Asp Ser Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gly Asp Tyr Tyr Gly Ser Asn Ser Leu Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Ser Val Thr Val Ser Ser 115 120 <210> 165 <211> 107 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 165 Asp Ile Val Met Thr Gln Ser His Leu Ser Met Ser Thr Ser Leu Gly 1 5 10 15 Asp Pro Val Ser Ile Thr Cys Lys Ala Ser Gln Asp Val Ser Thr Val 20 25 30 Val Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ser Pro Arg Arg Leu Ile 35 40 45 Tyr Ser Ala Ser Tyr Arg Tyr Ile Gly Val Pro Asp Arg Phe Thr Gly 50 55 60 Ser Gly Ala Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Val Gln Ala 65 70 75 80 Glu Asp Leu Ala Val Tyr Tyr Cys Gln Gln His Tyr Ser Pro Pro Tyr 85 90 95 Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 166 <211> 118 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 166 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Tyr Ile Phe Thr Asn Tyr 20 25 30 Asn Ile His Trp Val Lys Lys Ser Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Ala Ile Tyr Pro Gly Asn Gly Asp Ala Pro Tyr Ser Gln Lys Phe 50 55 60 Gln Gly Lys Ala Thr Leu Thr Ala Asp Thr Ser Thr Ser Thr Thr Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Val Arg Ala Asn Trp Asp Val Ala Phe Ala Tyr Trp Gly Gln Gly Thr 100 105 110 Leu Val Thr Val Ser Ser 115 <210> 167 <211> 106 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 167 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Lys Ala Ser Gln Asp Ile Asp Arg Tyr 20 25 30 Met Ala Trp Tyr Gln Asp Lys Pro Gly Lys Ala Pro Arg Leu Leu Ile 35 40 45 His Asp Thr Ser Thr Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Arg Asp Tyr Thr Leu Thr Ile Ser Asn Leu Glu Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Leu Gln Tyr Asp Asn Leu Trp Thr 85 90 95 Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 100 105 <210> 168 <211> 121 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 168 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Asp Asp Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Ala Ile Thr Trp Asn Ser Gly His Ile Asp Tyr Ala Asp Ser Val 50 55 60 Glu Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Val Ser Tyr Leu Ser Thr Ala Ser Ser Leu Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 169 <211> 107 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 169 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Arg Asn Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Ala Ala Ser Thr Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Val Ala Thr Tyr Tyr Cys Gln Arg Tyr Asn Arg Ala Pro Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 <210> 170 <211> 123 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 170 Gln Val Gln Leu Gln Gln Ser Gly Pro Glu Leu Val Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Ala Ser Gly Tyr Ser Phe Thr Ser Tyr 20 25 30 Trp Ile His Trp Ile Lys Gln Arg Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Met Ile Asp Pro Ser Asp Gly Glu Thr Arg Leu Asn Gln Arg Phe 50 55 60 Gln Gly Arg Ala Thr Leu Thr Val Asp Glu Ser Thr Ser Thr Ala Tyr 65 70 75 80 Met Gln Leu Arg Ser Pro Thr Ser Glu Asp Ser Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Leu Lys Glu Tyr Gly Asn Tyr Asp Ser Phe Tyr Phe Asp Val 100 105 110 Trp Gly Ala Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 171 <211> 107 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 171 Asp Ile Gln Met Thr Gln Ser Pro Ala Ser Leu Ser Val Ser Val Gly 1 5 10 15 Asp Thr Ile Thr Leu Thr Cys His Ala Ser Gln Asn Ile Asp Val Trp 20 25 30 Leu Ser Trp Phe Gln Gln Lys Pro Gly Asn Ile Pro Lys Leu Leu Ile 35 40 45 Tyr Lys Ala Ser Asn Leu His Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Ala His Ser Tyr Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 172 <211> 118 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 172 Glu Val Gln Leu Lys Glu Ser Gly Pro Gly Leu Val Ala Pro Gly Gly 1 5 10 15 Ser Leu Ser Ile Thr Cys Thr Val Ser Gly Phe Ser Leu Thr Asp Ser 20 25 30 Ser Ile Asn Trp Val Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Leu 35 40 45 Gly Met Ile Trp Gly Asp Gly Arg Ile Asp Tyr Ala Asp Ala Leu Lys 50 55 60 Ser Arg Leu Ser Ile Ser Lys Asp Ser Ser Lys Ser Gln Val Phe Leu 65 70 75 80 Glu Met Thr Ser Leu Arg Thr Asp Asp Thr Ala Thr Tyr Tyr Cys Ala 85 90 95 Arg Asp Gly Tyr Phe Pro Tyr Ala Met Asp Phe Trp Gly Gln Gly Thr 100 105 110 Ser Val Thr Val Ser Ser 115 <210> 173 <211> 111 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 173 Asp Ile Val Leu Thr Gln Ser Pro Ala Ser Leu Ala Val Ser Leu Gly 1 5 10 15 Gln Arg Ala Thr Ile Ser Cys Arg Ala Ser Glu Ser Val Asp Ser Tyr 20 25 30 Gly Gln Ser Tyr Met His Trp Tyr Gln Gln Lys Ala Gly Gln Pro Pro 35 40 45 Lys Leu Leu Ile Tyr Leu Ala Ser Asn Leu Glu Ser Gly Val Pro Ala 50 55 60 Arg Phe Ser Gly Ser Gly Ser Arg Thr Asp Phe Thr Leu Thr Ile Asp 65 70 75 80 Pro Val Gln Ala Glu Asp Ala Ala Thr Tyr Tyr Cys Gln Gln Asn Ala 85 90 95 Glu Asp Ser Arg Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 174 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <220> <221> VARIANTE <222> (1)...(5) <223> Puede estar ausente o presente, o presente en repeticiones de hasta 5 veces <400> 174 Gly Gly Gly Gly Ser 1 5 <210> 175 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 175 Gly Gln Pro Lys Ala Ala Pro 1 5 <210> 176 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 176 Asp Lys Thr His Thr 1 5 <210> 177 <211> 6 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 177 Thr Lys Gly Pro Ser Arg 1 5 <210> 178 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 178 Ala Ala Ser Thr Leu Gln Ser 1 5 <210> 179 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Constructo Sintético <400> 179 Lys Ala Ser Asn Leu His Thr 1 5