SEQUENCE LISTING <110> SOFAR SpA <120> Exopolysaccharides and uses thereof <130> 71.S0662.12.WO.10 <160> 13 <170> PatentIn version 3.5 <210> 1 <211> 18746 <212> DNA <213> Artificial Sequence <220> <223> Lactobacillus paracasei strain DG Exopolysaccharide-b region <400> 1 ccatctttag attattaaat aatattatcc tagattgcaa taataaagtt accacctaga 60 aagaggcttg ctcactgctt gaactggggt ttgccaacgg agacattttc taggtttgtt 120 attgataaac gctgtggctc gttgaatatt ggcctctgaa acctgatcaa actgtgttcc 180 cttcgggaaa tagtagcgaa gttctcgatt gaaccgttcg ttcgtgcccc gttcattcgg 240 gtgataggca tggcaaaagt aaatcggtat ccgatagcgc tttgtaagcg cctgatcgca 300 ggaaaactct ttaccgtgat caaccgtcac tgatcgaacc ggacccggaa agtctaccat 360 cagtcttgca aatcctttga gaacagcatt ttgtgataag ttttcaagct tagttgtcgc 420 cattaaacgt gtcacccgat cgacaatggt caaaacagca gcctttgacc cgcgaccacc 480 gcgaactgta tccatctcta aatgtccttt ttcggttcgc cgattagctg actcactgcg 540 aatctcaatt gaggtgccta ctgcttggtt atagcgcgac cgaaggtctt gtcttctttt 600 atgacgttta ccgtgatcaa agagttggct tggctgaaaa tcgacttgtc tttgataaat 660 ccagtggtaa atcgtgtgtg gcgcacagtg aacgacataa ccgaccattt caggggacca 720 acctaggttt agcttctcag ttaccatccg cttcaactta ggcgttaaaa tcgagtgccg 780 accacaacga tgccgacaag tatcggcatg atcctgagct ataatggcgc agtaatcacc 840 ttcagggcaa cggtgaagct catgcctaat agaaatacga gagcggccta aggtcgcggc 900 gatgtattga atcgtgtggt gttgcatcag ttctatctga gatcgttcaa ttaaggttat 960 aatggccatg ggacctgtcc ttctctctag atggtatgtt atgcaaacac cattttagca 1020 agaacggaca ggtctttttt cacattttct gggtggtaac tttaattatg caatctaggt 1080 tataaaatct tttgatagcc cggcgtttca tctaatgtta aagcataacg ccgcacatta 1140 aaggtggggg aaaccatgtt agacaatatc gggaaattgg tgcaccaaca gcgccgcagt 1200 ttgaacttga cgattgagaa gttggcggag cgatccggcg tctcgatcag tctgatttcg 1260 cgaatggagc gtggagacgt caacaatatc agcataaaaa aattgaccga cattgcgcgg 1320 gctttaaata tgcaggtagg cgacttcttt attgctccgg aaatgagcga tattagcaca 1380 ttagcggtgg tgaaatactt aacccactta ccagagaaag aacgggcgcg tgtttccgag 1440 gtactcatgc aggtgattaa cctgtaagta ccaccttttt agaacagtct gtcacttgag 1500 gctgttcttt tttgatatca aaaatgtcag aatgacctta aaaggatggc gcaacccgtt 1560 gtcagtcagc tggtaaaacg cgtatactaa atgcactgat tttagacaat gaacgcgaac 1620 ttgcacggtt agcttggttt gacaaagtgg cactgaatag ttgatcaagt atttgttcgg 1680 ctaacaggct ttcttcacaa taaccaaccg ccatgtggag aacgcatttt aaaagaagga 1740 gaatgatcga catgacattt gaagcaattt taccgtcctt taaagccggc aagaaggccg 1800 ttcgcaccgg ctgggaaggt actgagttgt atgtgcaact agttccggaa ggcaaattcg 1860 aaggcgacac tttgaatccg tattttttga tcaaaactgc cgacgaagct ttcagtctct 1920 ggtcaccgac tgactgtgac attttggctg aagactggca gcttgtgaac gcatgacgca 1980 tttcgacttc accgacaaga ccgtcatcat caccggcgcg gcttctggca tcggtgcggc 2040 tcaggcggcg gcttttcagg cagctggtgc cactgtggta ggaattgacc tccaaccaat 2100 tagcaacctc acagacgcca ttcaggccga tgtgagcgat cctgccacgg cagcagcgat 2160 tgcggctcaa taccagccag atattgtctg caatacggcg ggcgtgttgg atggttatca 2220 aactgtgacc gatacggcgc tctcggcatg gcagcacatt ctcgatgtcg atcctaccag 2280 tcagttctta atgatcaagg cgctgctgcc ggggatgctg gctcgcggtc acggtatttt 2340 catcaatatg agttccatcg ctggtttagt cggtggtggt ggcggcttgg cgtatactgc 2400 tgctaagcac gccgtcatcg tcctcaccaa gcaattagac cttgattacg ccgccaaggg 2460 cattcgcgcc aacgcgctcg caccaggcgc tatcaacacg cccatgaacg ccgctgattt 2520 tgccggcgac gggaaaatgg ctgcgtgggt agcgcgcgaa accccagcca aacgctgggc 2580 caagcccgag gaagtcgcac aattatcctt gtttctggcc agcgatgctg ctgattatat 2640 tcatggaacc gtgattccca ttgacggcgg ctggctcgaa aagtaaactt aatgcattgc 2700 aacaccaaaa ctgaaaacgg aaggcaatcc ttccacgacg atacttactt tcctttgatc 2760 gtcgttacta ctggcatagc cacaaaggag aacaaacatg caaacaactt caaccaccca 2820 tcgttcaatc gtcagtctcg ccaaaaccgc catgatcacg tccatttacg tcgtgatgac 2880 cctcatgctc agtccactca gcttcggggt cgtacaagtt cggttctccg agatgctcaa 2940 ctacacggca ctcttcaacc gccgttatgt ctggggcgtc acgctgggtg tttttttggc 3000 caatttaacc tcgtcaaccg cactcctcga tgtcccaatc ggcaccctcg gcacgctcgt 3060 cttcatcatc atcagccgct ggttagccaa actcgtccaa ccaaaatggg ctaaattcac 3120 catcatgggt atccttttcg ccttatccat gttcaccatt gccggcgaac tgaccatcct 3180 cacaaaagtc ccattctggc caacctacgc taccatcgcg cttggcgaag ccatctcgat 3240 ggccgtcggt ggcgttgtga tgatgatttt gacgcgattt gtggatttgg ataagtaggc 3300 gataaggcta ttgaaagagg ctcctataga aaaaagctta ctggcaggaa aggtttcgct 3360 gaagcttttc gatctggcag aagggcaagc aggtctgatt gctgtgttca aaagttgtcg 3420 caggggttag gcttccgatg cacctgattt tggttaaata ttggttaaat acaaaaaagc 3480 atcaagacaa ttgtctcgat gcttttttta atggaaggga tacgccctaa atctttttta 3540 agcaagatgc taatcctagg taatgatggt cttttcattg ttactttttc aatgtctgca 3600 tgacatcctt agcaatcaac gtgtagtaat gcggccggcc agcgtcgttc ggatggacac 3660 cgtcatcagc aaaccagtcg tcattgccac ctgccagata ataccaatcc accacatgca 3720 gattggcatg ggttttagct gccgcatgaa tcagcttgtt aaccggatca atccacgctt 3780 tccccggagc atacgcggtc acccagaaga cctgacgctc agtcccaagc tgatccagaa 3840 tcccgttaat gtcggcctct gtcataggtc cgttcgtccc caaactgatc acaaccgtgt 3900 tagccaactt accacttgcc ttcagctgac taataatcgc aggtgctgcc tgcacctgcc 3960 gaccaacctc agcatcaatc gacatctccg gaaaaagcac cttcaaatat gccgaactcc 4020 ccagcataat cgaatcgcca atcgccgaca ccggcaatgt tttggccgca ttaatctcgc 4080 tgtcagttaa gccataaagc cgatactgat tcagaacctt ttccttcttc accttcgcct 4140 tagaatcctt ctgaatgcgc tgccgcgtcg attggttaac cgcaatcgcc tgctcagact 4200 gataatgctt gacgtagaag aaccccgcga caccagcagt tgccaatccc aacgcgatac 4260 ttaatagcca gtctcgtaga cgtagcttgt tttttttcat gatttagtga acccccaaaa 4320 tttgcattgc ttatatttta aactaaaaat caggttagtc tgattacaag ttagggtcat 4380 tctgacgggt ttataggaaa ctgtaaatag actgtaataa aatgaaattt gaagttacca 4440 accttagtaa aaggcgtgta tatcggattc aaactaatct gatagtacaa ccaaaaacat 4500 gacattcatt caaaacaggt agacttcgtc acacatgcta ggttattatg gtttggagta 4560 gagttttaaa agtctttttt agaaatgcgg gctgcgctgc ttgtggtccg cattttgagt 4620 gttggatata aattatggga ttaggtgggg aaagagttaa tgaacaagca aatcgacctt 4680 tcgcagttgt ggaatgtatt taaacgcagc tttgttgcaa tgattattct cggaattctt 4740 gggatggcgg ctgcttattt cggtgctaaa acgtttattt cgccaaaata tgagtctgat 4800 acgtcattgc tggtcaatcg caagcaggat aacgatccaa acatgcaatt gaatgctcag 4860 caggctgata ttcagatcat taatacatac aaggacatta tcacacgtcc agtcgtttta 4920 caggctgttg cgagtgaact aacaagtccc cagcgtgtat tgataaaaaa agctacaaag 4980 gcggtttatg gtacgcgtta caatgcaaca acaggtgttc gagaagaata tgttactcaa 5040 aaagctcaac cggcgcaata taagttaaag ccagctcaat actccaatct ttcatctacc 5100 gatcttgcta aggtcgtaac agtatccaca cagcaaaatt ctcaagtgtt taccgttaac 5160 gttaaagata cagatcctgt tcgggcaaga gatattgcaa atgaagttgc taaggttttt 5220 gaaaagaaaa ttgctaaaat catgagcatt tccaatgttt ccgttgtttc aagggcaacg 5280 gctgatccga taccagtatt gcctcggttg aatctaatgg cattaattgg cctagtttta 5340 ggagtgcttg tcgctttcgt ttggggattg attcgagaac tgacagatca gaccattaag 5400 gatattgact ttatcacgga cgaccttggg ttggttaatt tgggaatagt caattatgtt 5460 caacatatgc gtgacatgag tgaagcgatc gatgccacaa agtcaataga agctgaggat 5520 actgaagatt acgatgcgtc ggactttccg caacgtagcc gtcgccgaat ctaaggagga 5580 agaaaacatg aagtggtctt tcaaacaact tttccaccgg caacaagaag atcaagaaac 5640 tcaaaagaac ggggtcattt tagtcacttt cgctgaacca aaacatgttg tttcagaaca 5700 gtttcgcaca gtgcgaacta atattgagtt tgctggagca gctcttgata agtgtcaagt 5760 tgttatgttt acgtcttcag tgatgtccaa gggcaagtcg actgtttcgg caaacgttgc 5820 ggtaacttgg gctcaggcgg ggaaaaaggt tttactgatt gattgtgacc ttcgacgacc 5880 gactgtacat gcaacttttc gaacgcttaa tctagaggga gtcacaacag tattaacggg 5940 gaaaagttct gctcacaata tagttgagca aacatttgtg agtaatttag atattcttac 6000 ctccgggccg ctacctccca ctccgtctga acttttaaat tcacaacgta tggctaacct 6060 cgtggattgg gcacgcgaca attatgatat tgttgttcta gatgcaccgc cagttttggc 6120 agtatctgat gtacaggtct tagtccccaa aacagatggc gtagtggttg tcgcaaagat 6180 ggggaagact ttaaagggag acttaagacg aactattgaa gttctgaagc ttgcaaaagc 6240 taaacttctt ggatgtgtag agcgtgtgaa tgttaaacgt ggcgatcgcg gctatggcta 6300 cggttatggc tacggttatg ggaatgaagg gactaaataa tccgatatta tcaacctaaa 6360 gaaaaaaggc atagctcaaa tatttataaa ttgatgctta acgcattgtt gtctgttttt 6420 gatgtttggg tggttatctg attatttatg tgatttaata gtggcaagaa aagtttataa 6480 atttaatata cttgcacaaa gatttttaag aatgcaagtt tttattcttg caaagttgaa 6540 aaagtgattt cgactttagc acggggaacg cgacatacta aagtcacttc acgtagtgcg 6600 tttgggggag gaaggatcat gtatcaacac ttcattaaaa gaattttaga tattttggga 6660 gcaataatag cattgctaat cttggcaatc ccgtttatca ttattgcaat acttattagg 6720 atggattcaa cgggtccagc cttttttcgt cagcaaagaa tggggaagga tgggaagccc 6780 tttagaattt acaagtttcg tacaatggac caagaggccc cacacgatct tgcaactgct 6840 aaactagata atgctaataa gcagattaca cgggtcggtc gattgctccg aaagacaagt 6900 attgatgagt tacctcagtt cattaatgtg ttaaagggcg acatgagcat ggtcggacca 6960 cgtccggttg tcttgacaga aactgagcta attgaaatgc gtcacaaaaa tggcgctgaa 7020 agtgctttac cggggataac aggattagcg caggtaaacg gaagagatcg gttatccaat 7080 ttaagtaaat ctaattacga tggtatttat gtttcttcaa tttcattttt tatagattca 7140 aagataatgg tcaaaacttt ctggtatgta gctcttcgat taggtattag agaaggtcgt 7200 ccaaattcta aaaaagttaa tgctgctaat atcggagaaa aaaatattag gccgaacgaa 7260 cagcaactat ttttaaaaag gaaagcttag atttaatgaa tgataatact aaagaaatta 7320 gcttttgtac cgttacttat aacagcgcaa aagaagtgac ccagttaata gaaaatatag 7380 agtctctaaa aagcgatttg ttttcctcac gagttttcat tgttgataat gggtcccaag 7440 atgacacagt gaatatagtt ttaaagcttt ctcaggaaca ctctaatctt gttttaatta 7500 ggcctgatgt gaatagggga tttggagcag gcaacaatca ggtgttaaat atgattacct 7560 cggattacca tattctgatt aatccagatg tgcgtatacc gtcctccaga acgattgaaa 7620 agatgatcgg gtatatggat actcattctg atgttggact gttatccccc aaaattctta 7680 atgttgacgg ctcagttcaa aaattattta gacataatcc tactgtactt gatatggcgt 7740 tacggttcat ctcacctaat cttatgaaaa aaaggcaaga ttggttcgtc catgaagaga 7800 ccgggtatac tcagagcgga gtgatcgatc aagctagtgg agcatttatg tttttccgta 7860 catctgtatt taaaggtata gcgggttttg atgagagata ctttatgtat ttggaggatg 7920 cagacattac tcgtaaggtc aatgctgtta gcaaagcaat tttttatcct gaagtaagca 7980 tcatgcataa gtggaatcga caaaatcatt caaagttgaa attcattggc tatacaatta 8040 agagcatggt tcaatatttt aacaaatggg gatggaagtt attctaacca ctggggagat 8100 tgattgaatg atttggctgg gaattgtctg tattagcttt atatctagtt gtttccaaaa 8160 attagagaag tcagcgggtt tgatatcttt tttgggttta ggttatttgg cgggcacacc 8220 aaatatgttg tacgatcccg atgcttttgt ctatttacaa aattataatt cgggcactga 8280 ttatttcgag acaggatata attgggtgac aaagctattt gagcctagtg tagattatca 8340 aacatttaga ttatacagta gtttatttat ttttttcctg atgtttttag cagtactttt 8400 gatgacaaag cacgtatcaa gtattgcgtt ggtttatgca atcgcaatgt ttccggttga 8460 taaagcacag actagaaatg tcatggcagc cgtcttttgt tcctttttgg agttcstgtt 8520 gttttgctgt aagcttggga aaagaggaat tcttccctca ttactggtca tttttattag 8580 gatctttttt tcatagtctt gcactctact ttcttttact accattatta tggttgttta 8640 aaggctttat tgaaaagcat ttttctgcaa ttactacatg tctaattgtt gttgcgttta 8700 tttttgaaat cttaggttca acaagcatag cgccactatt agtacaactt ttgggaaagt 8760 ttgcaaatcg tgcgaacgtt gcagaaaatg tgtcaacttt atatgctgga ggtcagccat 8820 ttagtcagtg gtttgtttct ttcgcagtta ctatgatgat aattttaaca gttcaatttc 8880 ttagaaggca ataccctaac aatatgagat cctattacca aatgatttta tgttcttcga 8940 tattatggtc agcagcgtta atattgatga ctctttcaat tgactacata agaattctga 9000 gaattgttac gtacttctat tttatctata tcgtgaatgt tacttcaaat cagaagagca 9060 cggatcgcct tataggggtg acaatcagta ttggatctgc agtcgttttg atgtttgtcg 9120 ggttatgggt ctacggattt agtggtgacc aaattcgagc aatttttggg tttatttaag 9180 gggactgaag aatgttgaaa gttggagtaa ttgttgttac ttacaatccg gatttaatga 9240 ttctacagaa taatctgacg acactaaaaa ggcaaaatgg catcaactgt ctgattgttg 9300 ataacggctc taagaattca aacgatttaa aaaaagtaag tgaaaactta aaagtcaaca 9360 ttatttcact tgatagtaat cgtgggattg cttatgcaca aaatcgaggt tttgaatttt 9420 ttcaaagaga agggttaaag tgggcgctta ctttagacca agacagcata gttcctgata 9480 acttactaga agtgtatgta aagcaaaaag aattgaactc ttccgacaca gcaattttaa 9540 cttgtagcta cgttgatgag gactggactg gaaagcaaaa agaagctatg cttcagcgtg 9600 aaaagattgt gcaaaagcaa tatgtcattt cttcaggtaa tcttgtaaga atttcctctt 9660 ggcaaaaagt gggtggattt gacgaattcc tctttattga catggttgac ttcgactttg 9720 acgctaaact atttttagct ggctttaaaa tctggcagac gaatgaagtc gtactaaaac 9780 attctgttgg acaatcctta aagaagccca tcgtgaaaaa aatacttctg attccagaaa 9840 ctgctatttt ggccgatcat tcaccaattc gtcagtatta catttataga aatagtatta 9900 ttttcgagaa aagatacacg atgattaccc aacgaaagtt tgttgttctc catactttcg 9960 ttgcaacaag gagaatgttt gcgtatagca ataagttacg caagatgttt gcagcttggc 10020 gcggagttat tgatggtgcc agatacaatg tagacaagga caaacaattt aaaaaaacac 10080 tggcaaaact gaaacgatag ttatttgggg tgaaataatg agaagtgaaa acgtaagtgt 10140 cgcaatttgt ttagccacgt ataacgggga gaagtattta gaaaaacaga ttgactcaat 10200 agtttcccaa tctgtctcta gttggacatt gtttattaga gatgatggtt ccaccgatgg 10260 aacgcaaaaa atcattaaaa agtttgcaaa gaagtatccg caaaaagttt tcaacttatc 10320 aggtcttcat ggaggcggaa attctaaaga aaattttttt actattctgc aatgggtgag 10380 cgaacacaaa acttttgatt attttatgtt ttctgatcaa gatgacattt ggttacctga 10440 taaaattgca ttaagtgtca aggctattga ttctgatgat tctccatgtt tagttcatac 10500 tgatctaaaa gttgtcgata aaaacttgga tacaataaca gaatctttca ttcggtacag 10560 taacttaaat tctcaagtaa aggatttttc gcatatcctt gtacagaaca atgtaactgg 10620 ctgcacaatg ttgtggaata agagtttaaa cgatttaatc gattttcatc cagattctag 10680 aatccttatg catgattggt ggattgcttt aattgcatca gcgtttggaa atgtcgtctt 10740 tgtaaaaact ccaaccatcc tctatcgaca acatgatgaa aatgtagtgg gggcagaagc 10800 ggctggttct gtggcatata ttatttcaaa attgcgtaat tataagttga ttaaaaaagg 10860 attgcaacgt acctttgggc aagcaaatat ttttaaagag atttattatc atcggttaga 10920 tgccagttct aaaagtatac tagatgagta tttgcagctt cctgccaagt ccaaacttag 10980 aaaaatatat ctttctctca agtatggatt tacaaaacaa agcaccatac aaattattgg 11040 gcagtttctt tttgtctagt ctgttgaggc tgattaattg cgagttttaa aaaattattt 11100 atatagtgtt gggtatcaag ttctaaacat gatattgcca ctcataacag gaccgtatgt 11160 tgcacgagtt cttggaccga agggtgttgg gattaatact tatacaggtg cagtaacaca 11220 atactttgtt ttattcgctg gcctagggat agcgctttat ggaaatcgac agattgctta 11280 tgttaagggt gacccacatc agttaagcat taccttttgg gaaatacagt ttattaaaac 11340 gattacaaca gtttgcgcct ttgtcgcttt ttcaatatat ttaattttcg tcaaagaata 11400 taagttttat ttactgttac aatccgcgta tattttagct acaggatttg atatttcatg 11460 gctttatgag ggcgttgagg attttaaaaa gacctttact agaaacacgt tagttcgaat 11520 agtctccctt gttctaatcc tcacgctggt acacaaacaa agtgacgttt gggtatacat 11580 agtcattctc gcagcttcta acctcggtgg gtatgttgcg ttgtggccaa ctctaaggcg 11640 gctgctcgta cccattaaac tgtctgaatt acatcctagg aaacatttga agggcacact 11700 gattttattt gtgccataca tgacgctgaa catttatcct atcattaata aaacattact 11760 caaacatttt cttggggttg atgcttccgg ttattttgaa aaaagtgatg tgatgatacg 11820 tatggcgttg acagtagtga cgtcggtaag cgcagtatta ctgccacata catccaaggc 11880 ttttgctgat ggcaaggttt cgttaattaa gaaattgcta aaaacctctt ttggatatgt 11940 gtccatgatg gcattcccaa tcgcattagg aatggcggca atagcaccaa aatttggtgt 12000 tttcttttat ggtgaagggt ttgcaccggt tgggccagca atgatgatag aatctagtgc 12060 cattattttc atggggtggt cgagcatcac aggtaatcag tatttaattc cgacgatgca 12120 gtcaaagcat tacacgcact cagttcttct aggctcggtt ttgaatattg ttcttgacgt 12180 tcctcttatc attatttttg ggcttaatgg tgcagcgttt gctactttga ttgctgaagc 12240 gtttattgct atatatcagt taataatgat cagtggtcag gttgattatt ccacttggct 12300 gatggacatc attaaatatt gtgtagctgc tataatcatg ttctgctttg tttttttcgc 12360 aagtagcatg ttgacgatga ccatcttgac cttagtgctt gaaatcatgc ttggtgccat 12420 catttactta gtatgtctgt ttcttatgaa acccgcaact aataagcaac tcaaacgggc 12480 agcattctca attattaacc gagttcggtc atgattattt ttgggggaat aatgacaata 12540 agacgaagag tttcttggtt gattcgttca cctgcacgat tacatgttgt gtatcggatt 12600 gacgatttta caaataattt gaaggttcga agactgttac atatactatt gatcccagtc 12660 ggcatgttaa acttaattag gctaaaactg atgactagat cacctgaaaa gtttatgtat 12720 caattatcaa ttgttactac agtcaaaaat gaggctccat acttaagaga gtggctgaga 12780 tatcacattt cggttggagt acagcacttt tatctttatg ataatgatag tcaagataac 12840 ttagatgaag tgttaaaaga tttttccgac tacgttactt taacaaagat acacggacga 12900 gttagacaat ttgatgcata caatgacgcg ataaatcgat tcaggtatga aacaaagtat 12960 atggcggtga tagacgcgga tgagtttatt tttagaccag gtaaagacaa gctgttacta 13020 cctcttattg attatttact ttcaaataag tcatttggag gattggcggt gaattgggca 13080 atatttggtt cttcgggttt aaaaaagaaa cctttaggat tggttaccga caactttgta 13140 tatcgggcca acgataactt taggaaaaac aggctggtta aaactatctg caatccgaga 13200 aaagtctttt acttttcagt tagccatgct gcaaattact tgccaggttt ttatgcagtt 13260 aatgagaatc aggaaaaagt tgattggaca acaacgcaag ttcccagtat cagtaagatt 13320 agaattaatc actattattc aaaatcacaa gaagagtttt tacgaaagcg agctcgaggc 13380 gctggggatg ttgttggcct tagagactta ggagaattcg cagaacatga tcgaaatgat 13440 gtttttgacg actcgcttag agtttataat gaatcaagag gtttaaacaa agactgaggg 13500 ggatattgaa agatgaaggg gattatatta gctgggggat ccggaactcg actctatcca 13560 attacgaagg caacaagtaa acagttagtt ccaatttatg acaagcccat gatttattac 13620 ccattctctg cgctaatgtt gtctgggatc aaagagtttc tgattatttc tacgccagaa 13680 tttctgccac agtttgaaga attatttggt gatggacata ctctgggact aaatattcat 13740 tacaaggttc aaacagagcc aaatggattg gctgaggcat ttatccttgg tgcggatttt 13800 atcggtaatg attccgttgc tttagtgctg ggagataatg ttttttatgg tgctgggtta 13860 tcaaagctat tacaagatgg ggccgcaaag gaatctggcg ccacaatttt tgggtatcag 13920 gtaactgatc ctgaacgttt tggtgtagta gaatttgata gccatcaaca cgctgtatcg 13980 attgttgaaa agccaaccca tccacgcagt aattatgcag taactggttt gtatttttat 14040 gataatgatg tggttaatat tgcaaaaaat gtaaagccat ctgcgcgtgg cgaacttgaa 14100 attaccgatg tgaatgagga atatcttcgt cgcgggcagc tagatgtaaa agttatgggc 14160 agaggttatg cttggttaga tactggaacg catgactcat tgcttgctgc ttcaagtttt 14220 gttgcaacta ttgagaatca acaaaatctt aaagtggcgt gtcttgagga aattgcttat 14280 cgtatggggt atattaatct tgaacagttg gaagaacttg cccagccgct caaaaaaaat 14340 gattatggtc agtatttgtt gcgtttggtc aaggaggaga gtaagtaatg gctttaaaag 14400 taatcccgac aaagttaact gatgtcaagt tggttgagac agatgttttt ggtgataatc 14460 gcggtttctt cacagaaacg tatactcgac ctaagtttca agaggcgggc atcacgaatg 14520 atttcaatca agataatcag tcattgtctg ctgaagcagg tgtgttaaga ggcatgcact 14580 accagatggc tccacatgca caaacaaaat tagttcgtgt ggtaactggt gttgttgaag 14640 atgttttggt tgacatccga aagggttcac caacttatgg tcagtgggaa ggatatattt 14700 taagcgaatt caaccatcgc caattacttg tgccaaaggg gtttgctcat gggtttatta 14760 cattaactcc aaatgttaat tttgcttata aggttgaagg gtattatgct cctgaagctg 14820 atcgtggaat tgcctttgat gatcctgaca ttggcattaa ttggccaatg tcaacagcac 14880 accttattat gtctgagaag gatcaacacc atccacagct gagggatgct gaaaataact 14940 ttgtatacgg ggagatttga taatgaaact tatgatcact ggcggggctg ggtttatcgg 15000 ttcaaatttt gttcattttg tttataataa ccatccagat gttcagatta tggttttgga 15060 caagctaaca tatgccggca ataaggccaa tattgaagat atcttgggcg atcgtgtcaa 15120 attagaagtc ggggatattg ccgacaagaa tttggtcgat aaattgatga gtgaagtcga 15180 tacagttgtc aactttgcgg cagaaagtca caatgacaat tcgttgatta atccggatcc 15240 gttcctgcac agcaatgtta ttggcaccta tactttactt gaagcagcaa gaaagtacga 15300 tgttcgattc caccatattt ccacagatga ggtgtacgga gatctaccat tacgtgcgga 15360 tcttccagga cacggggaag gccctggcga gaagttcacc gttaacagtc gttataatcc 15420 ttccagccca tattcttcaa ctaaagctgc cagtgacatg ttggtacatg catgggcacg 15480 ttcatttggc gtacgcgcaa caatttctaa ttgctcgaat aactatggtc cataccaaca 15540 cattgagaaa ttcattcctc ggcaaatcac aaacatttta agcggaatca aaccgaagct 15600 ttatggcact ggcaaaaatg ttcgtgattg gattcacaca aacgatcatt caagtgctat 15660 ctgggatatt ttgactaacg ggaaaattgg tgagacttac ttgatcggcg ccaatggcga 15720 aaaagacaat aagacggtac tcgaacttat cttaaaattg atgggcaaac cagctgatta 15780 ctatgaacag gttaaggatc gtccggggca tgatatgcga tatgccattg atgcttccaa 15840 aacccgtgaa gaacttggtt gggaacctca gtatacgaat tttgaagaag gtttagcaga 15900 taccatcaaa tggtacacag atcatcacag ctggtggcaa ggtgaaaaga ctgcggtaga 15960 agaaaagtac caagaaaacg gtcaatgact ttagctcata gtaatggtcg tcactaatta 16020 tgaacctgtt attttctgga atgtcgagga gaagatacat gaagactttg attactggtg 16080 cgcaaggtca gcttggtaca gaattgcgcc gcctattaga tgcgcagggc gttgcttatc 16140 gagcaacaga tgcccatgat ttagacatta ctgatgagac tgcggttaat cagtatttta 16200 aagattatca acccgagtta gtttatcact gtgctgccta tacggctgtc gataaggctg 16260 aaggtgaagc taaggcaatt aatcaaaaag ttaatgttga cggaacacgt aatttggcaa 16320 aagcggccgc tgaagtagat gcgacacttg tttacatcag tacagattat gtatttgatg 16380 gtgacagcaa agaaatttat accgtcgatg atcaacctgc tccacgtaat gagtatggcc 16440 gggcaaaata tgaaggtgag caacaagtcc aaaaatatct taagaagttc tatattatta 16500 gaacctcatg ggtattcggt gaatttggtc ataactttgt ttatacaatg ttggacttag 16560 ccaagacaca caaagaactc agcgttgtcg acgatcaata cggtcgtccg tcatggacca 16620 agacactcgc agaattcatg acgttcgcag tgaatcaaca tttggattat ggcatttacc 16680 acttgtctaa tgataacagt tgtaactggt acgaatttgc tagcgctatt ttggctgaca 16740 aagatgttga tgttaagcca gtatcgtcat cagagtatcc gcagaaggca tggcgtccgc 16800 gacattcgat tttggactta agtaagacga aggttacagg ctttaagata gacacttggc 16860 aagaagcttt gacaaacttt ttacaagtta tcgataaata agtgaaacta gatcaagtgt 16920 atcaaaaaga acgtaaaaac caatctggcg attggtttcg gcgccctttt gatacacgta 16980 acaataacgg gtctacactt tctggtgttg agaaataatc agcactgaac gtgtaggccc 17040 tttttggata acgcaaaaag acacctattc agtgaccatg ctatgcttgt tagcgtcgaa 17100 accaaaagca agcgaggtta tgagtaaatg tcccaatacg attctacact gtccgtcctt 17160 ggaataccag accataatat caaagtagcc tttgttcgtc atgaatatcg cggcaacggg 17220 gtacgtcgcc gccagtatca tgtgattgat gctgagctga cttaccggtt acactgtgtg 17280 gctttgaggc cttgcaccct aacgggtttt acacggccca tgtgcgcgtc ctcaacgggg 17340 ttgaaatgcc gacagtcatt gacttgcaca agcaacgatg gcgctgtcat aactgttacc 17400 acacagtcag tgccaagacg ccactcgtgc aacccaacca cacgatcgcc gctcacatga 17460 cagagcgaat catgaagtta gcgcatgaac ggttgccagt caaaaccatc gcccgtatta 17520 tcggaatctc agcctcctcg gttcaacgga tcattgacca aaatctcaaa ctccgaccgg 17580 ctcgccggct acccacgcga ctctgctttg atgagttccg ttccactcat ggcatgatgt 17640 cgtttatctg tcttgatgcc gattcacatc atctgattgc cttgcttggt gatcgatgca 17700 accgcacgat taaaaacttc ttcctcgctc attattcact cgctgaacgc actcgggtcc 17760 agacggtcac catggacatg aatgcagctt atcagacgat tattcatgag gttttcccca 17820 aggcccaagt cgtcattgat cggttccata tcattcaact tgcggctcgt gcccttgatc 17880 aggtacgcgt ccaagcgctc aaacagcttg atgacaaaca cagccgtcct tataagatca 17940 tgaagacaaa ctggcggctt tttcatcaaa ctgcgcctga cgctaaacac aaacagttcc 18000 tgtttggttt gaatgaagac gtcacgcaac aggaggccat cgatattgca cttgatactg 18060 agcccaagct caagcaaacc tacgagacct acttagcgct tcatgatgct ttgatggtga 18120 agaaacatcc cgcggaactg gcaaacctgt tagctactta cgagccaaac ggtacggcaa 18180 tggacatgac gatcgcgacg cttaagcgac acaaagtcgc tgttctcgcc gctgtcacca 18240 gcccttattc caacggtccg atcgaagggt taaccgcctc atcaagtcac tcaaacgatc 18300 ctgttttggc ttcaagaatc agctgaactt cttcaaacga atcataccaa atcacggcat 18360 aacatgacaa agacggcggc atgatcctga agctataata ggcgcagtaa tcaccttcag 18420 ggcaacgtga agctcatgcc taatagaaat acgagagcgg cctaaggtcg cggcgatgta 18480 ttgaatcgtg tggtgttgca tcagttctat ctgagatcgt tcaattaagg ttataatggc 18540 catgggacct gtccttctct ctagatggta tgttatgcaa acaccatttt agcaagaacg 18600 gacaggtctt ttttcacatt ttctgggtgg taactttaat tatgcaatct aggcattaag 18660 ggtcaaatta ccagatgata atatgcctga ttcattaata atcgcgtgtg aaaaaggaac 18720 attaatctta ggagaattga tgatcg 18746 <210> 2 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> GAPDH forward <400> 2 gggaaggtga aggtcggagt 20 <210> 3 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> GAPDH reverse <400> 3 tcagccttga cggtgccatg 20 <210> 4 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> IL-6 forward <400> 4 cggtacatcc tcgacggcat 20 <210> 5 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> IL-6 reverse <400> 5 tcaccaggca agtctcctca t 21 <210> 6 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> IL-8 forward <400> 6 tgtggtatcc aagaatcagt gaa 23 <210> 7 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> IL-8 reverse <400> 7 tatgttctgg atatttcatg gtaca 25 <210> 8 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> CCL20 forward <400> 8 ctgcttgatg tcagtgctg 19 <210> 9 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> CCL20 reverse <400> 9 cacccaagtc tgttttgg 18 <210> 10 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> TNF-alfa forward <400> 10 tcagctccac gccatt 16 <210> 11 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> TNF-alfa reverse <400> 11 cccaggcagt cagatcat 18 <210> 12 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> COX-2 forward <400> 12 cccttgggtg tcaaaggtaa 20 <210> 13 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> COX-2 reverse <400> 13 tgaaaaggcg cagtttacg 19