LISTADO DE SECUENCIAS <110> KITE PHARMA, INC. <120> RECEPTORES QUIMÉRICOS Y MÉTODOS DE USO DE LOS MISMOS <130> K-1029.02US <140> 15/476,699 <141> 2017-03-31 <150> 62/317,068 <151> 2016-04-01 <160> 147 <170> PatentIn versión 3.5 <210> 1 <211> 294 <212> ADN <213> Homo sapiens <400> 1 cttgataatg aaaagtcaaa cggaacaatc attcacgtga agggcaagca cctctgtccg 60 tcacccttgt tccctggtcc atccaagcca ttctgggtgt tggtcgtagt gggtggagtc 120 ctcgcttgtt actctctgct cgtcaccgtg gcttttataa tcttctgggt tagatccaaa 180 agaagccgcc tgctccatag cgattacatg aatatgactc cacgccgccc tggccccaca 240 aggaaacact accagcctta cgcaccacct agagatttcg ctgcctatcg gagc 294 <210> 2 <211> 98 <212> PRT <213> Homo sapiens <400> 2 Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly Lys 1 5 10 15 His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe Trp 20 25 30 Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu Val 35 40 45 Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg Leu 50 55 60 Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr 65 70 75 80 Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr 85 90 95 Arg Ser <210> 3 <211> 90 <212> ADN <213> Homo sapiens <400> 3 cttgataatg aaaagtcaaa cggaacaatc attcacgtga agggcaagca cctctgtccg 60 tcacccttgt tccctggtcc atccaagcca 90 <210> 4 <211> 30 <212> PRT <213> Homo sapiens <400> 4 Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly Lys 1 5 10 15 His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro 20 25 30 <210> 5 <211> 81 <212> ADN <213> Homo sapiens <400> 5 ttctgggtgt tggtcgtagt gggtggagtc ctcgcttgtt actctctgct cgtcaccgtg 60 gcttttataa tcttctgggt t 81 <210> 6 <211> 27 <212> PRT <213> Homo sapiens <400> 6 Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu 1 5 10 15 Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val 20 25 <210> 7 <211> 123 <212> ADN <213> Homo sapiens <400> 7 agatccaaaa gaagccgcct gctccatagc gattacatga atatgactcc acgccgccct 60 ggccccacaa ggaaacacta ccagccttac gcaccaccta gagatttcgc tgcctatcgg 120 agc 123 <210> 8 <211> 41 <212> PRT <213> Homo sapiens <400> 8 Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr 1 5 10 15 Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro 20 25 30 Pro Arg Asp Phe Ala Ala Tyr Arg Ser 35 40 <210> 9 <211> 336 <212> ADN <213> Homo sapiens <400> 9 agggtgaagt tttccagatc tgcagatgca ccagcgtatc agcagggcca gaaccaactg 60 tataacgagc tcaacctggg acgcagggaa gagtatgacg ttttggacaa gcgcagagga 120 cgggaccctg agatgggtgg caaaccaaga cgaaaaaacc cccaggaggg tctctataat 180 gagctgcaga aggataagat ggctgaagcc tattctgaaa taggcatgaa aggagagcgg 240 agaaggggaa aagggcacga cggtttgtac cagggactca gcactgctac gaaggatact 300 tatgacgctc tccacatgca agccctgcca cctagg 336 <210> 10 <211> 112 <212> PRT <213> Homo sapiens <400> 10 Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly 1 5 10 15 Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr 20 25 30 Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys 35 40 45 Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys 50 55 60 Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg 65 70 75 80 Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala 85 90 95 Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 100 105 110 <210> 11 <211> 117 <212> ADN <213> Homo sapiens <400> 11 attgaggtga tgtatccacc gccttacctg gataacgaaa agagtaacgg taccatcatt 60 cacgtgaaag gtaaacacct gtgtccttct cccctcttcc ccgggccatc aaagccc 117 <210> 12 <211> 39 <212> PRT <213> Homo sapiens <400> 12 Ile Glu Val Met Tyr Pro Pro Pro Tyr Leu Asp Asn Glu Lys Ser Asn 1 5 10 15 Gly Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu 20 25 30 Phe Pro Gly Pro Ser Lys Pro 35 <210> 13 <211> 288 <212> ADN <213> Homo sapiens <400> 13 gctgcagcat tgagcaactc aataatgtat tttagtcact ttgtaccagt gttcttgccg 60 gctaagccta ctaccacacc cgctccacgg ccacctaccc cagctcctac catcgcttca 120 cagcctctgt ccctgcgccc agaggcttgc cgaccggccg cagggggcgc tgttcatacc 180 agaggactgg atttcgcctg cgatatctat atctgggcac ccctggccgg aacctgcggc 240 gtactcctgc tgtccctggt catcacgctc tattgtaatc acaggaac 288 <210> 14 <211> 96 <212> PRT <213> Homo sapiens <400> 14 Ala Ala Ala Leu Ser Asn Ser Ile Met Tyr Phe Ser His Phe Val Pro 1 5 10 15 Val Phe Leu Pro Ala Lys Pro Thr Thr Thr Pro Ala Pro Arg Pro Pro 20 25 30 Thr Pro Ala Pro Thr Ile Ala Ser Gln Pro Leu Ser Leu Arg Pro Glu 35 40 45 Ala Cys Arg Pro Ala Ala Gly Gly Ala Val His Thr Arg Gly Leu Asp 50 55 60 Phe Ala Cys Asp Ile Tyr Ile Trp Ala Pro Leu Ala Gly Thr Cys Gly 65 70 75 80 Val Leu Leu Leu Ser Leu Val Ile Thr Leu Tyr Cys Asn His Arg Asn 85 90 95 <210> 15 <211> 366 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 15 caggtgcagc tgcaggaatc cggaccgggg ctggtgaagc ccagcgagac tctgagtctc 60 acgtgtacag tttctggagg tagcattagc tcctactatt ggtcatggat aaggcagccc 120 cccgggaagg gattggaatg gatcggctat atttactaca gtgggagcac caattacaac 180 ccctcactga agtctagagt tacaatcagc gttgacacct caaagaatca gttcagtttg 240 aaattgtcta gcgtcacagc agctgataca gccgtctatt attgtgtttc tctggtctat 300 tgcggtgggg attgttacag tggctttgac tattgggggc agggtactct ggttacagtt 360 tcttcc 366 <210> 16 <211> 122 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 16 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 20 25 30 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile 35 40 45 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu 65 70 75 80 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val 85 90 95 Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp 100 105 110 Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 17 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 17 Gly Gly Ser Ile Ser Ser Tyr 1 5 <210> 18 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 18 Tyr Tyr Ser Gly Ser 1 5 <210> 19 <211> 14 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 19 Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr 1 5 10 <210> 20 <211> 324 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 20 gacatccagt tgacacagag cccgagttcc ttgtccgcct ccgtcgggga tagagtgtca 60 tttacctgtc aggcctctca ggatattaat aactttctga attggtatca gcaaaagccc 120 ggaaaggcac ccaagctgtt gatttacgac gccagtaacc tggagacagg cgtgccctcc 180 cggtttagtg gtagcggaag cggtacggat tttaccttta ctatcagctc tctccaaccc 240 gaagacattg caacctacta ttgtcaacaa tatggaaacc tgccttttac atttggcggc 300 ggcaccaagg tggagattaa gcgg 324 <210> 21 <211> 108 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 21 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg 100 105 <210> 22 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 22 Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn 1 5 10 <210> 23 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 23 Asp Ala Ser Asn Leu Glu Thr 1 5 <210> 24 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 24 Gln Gln Tyr Gly Asn Leu Pro Phe Thr 1 5 <210> 25 <211> 1440 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 25 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtcc aactgcaaga aagcggaccc ggactggtga agccttctga gacacttagt 120 ctgacgtgca cggtcagtgg cggctccatc tcctcctatt attggtcatg gatacgacaa 180 cccccaggta agggcctgga atggattggc tatatctact attcaggaag cacgaactac 240 aatcccagcc tgaagtcccg agtgacaatt tcagtagata ccagtaaaaa ccagttcagt 300 cttaaactgt caagcgtgac agctgccgac accgctgtgt attactgcgt ctcactggtg 360 tattgtggag gggattgtta tagcgggttc gattattggg gacagggaac cctggtgact 420 gtatcttccg gcggcggcgg ctcagggggt ggcggtagtg gcggtggggg ttccgatatt 480 caactgacac aatcccccag ctcactcagc gccagcgtgg gggacagggt tagctttacc 540 tgtcaagcct ctcaggatat aaataacttt ctgaactggt atcaacagaa gcctgggaag 600 gcgcccaaac tcctgatcta tgatgcgtcc aacctggaaa ctggcgtgcc ttcacgcttt 660 agcggctctg gcagtggtac agacttcact tttaccatct cttcacttca gccggaggac 720 atcgccacat attactgtca acagtacgga aacttgccct ttacttttgg aggcggcacc 780 aaagttgaaa tcaaaagggc cgctgccctg gataacgaaa agagcaatgg gactataata 840 catgttaaag gaaaacacct gtgtccatct cccctgttcc ctggaccgtc aaagccattt 900 tgggtgctcg tggttgtcgg tggcgttctc gcctgttata gcttgctggt gacagtagcc 960 ttcattatct tttgggtgag atccaaaaga agccgcctgc tccatagcga ttacatgaat 1020 atgactccac gccgccctgg ccccacaagg aaacactacc agccttacgc accacctaga 1080 gatttcgctg cctatcggag cagggtgaag ttttccagat ctgcagatgc accagcgtat 1140 cagcagggcc agaaccaact gtataacgag ctcaacctgg gacgcaggga agagtatgac 1200 gttttggaca agcgcagagg acgggaccct gagatgggtg gcaaaccaag acgaaaaaac 1260 ccccaggagg gtctctataa tgagctgcag aaggataaga tggctgaagc ctattctgaa 1320 ataggcatga aaggagagcg gagaagggga aaagggcacg acggtttgta ccagggactc 1380 agcactgcta cgaaggatac ttatgacgct ctccacatgc aagccctgcc acctaggtaa 1440 <210> 26 <211> 479 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 26 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu 20 25 30 Val Lys Pro Ser Glu Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly 35 40 45 Ser Ile Ser Ser Tyr Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys 50 55 60 Gly Leu Glu Trp Ile Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr 65 70 75 80 Asn Pro Ser Leu Lys Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys 85 90 95 Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 100 105 110 Val Tyr Tyr Cys Val Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser 115 120 125 Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly 130 135 140 Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile 145 150 155 160 Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg 165 170 175 Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn 180 185 190 Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp 195 200 205 Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly 210 215 220 Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp 225 230 235 240 Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe 245 250 255 Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Leu Asp Asn 260 265 270 Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly Lys His Leu Cys 275 280 285 Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val 290 295 300 Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala 305 310 315 320 Phe Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser 325 330 335 Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His 340 345 350 Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg 355 360 365 Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln 370 375 380 Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp 385 390 395 400 Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro 405 410 415 Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp 420 425 430 Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg 435 440 445 Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr 450 455 460 Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 465 470 475 <210> 27 <211> 1374 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 27 caggtccaac tgcaagaaag cggacccgga ctggtgaagc cttctgagac acttagtctg 60 acgtgcacgg tcagtggcgg ctccatctcc tcctattatt ggtcatggat acgacaaccc 120 ccaggtaagg gcctggaatg gattggctat atctactatt caggaagcac gaactacaat 180 cccagcctga agtcccgagt gacaatttca gtagatacca gtaaaaacca gttcagtctt 240 aaactgtcaa gcgtgacagc tgccgacacc gctgtgtatt actgcgtctc actggtgtat 300 tgtggagggg attgttatag cgggttcgat tattggggac agggaaccct ggtgactgta 360 tcttccggcg gcggcggctc agggggtggc ggtagtggcg gtgggggttc cgatattcaa 420 ctgacacaat cccccagctc actcagcgcc agcgtggggg acagggttag ctttacctgt 480 caagcctctc aggatataaa taactttctg aactggtatc aacagaagcc tgggaaggcg 540 cccaaactcc tgatctatga tgcgtccaac ctggaaactg gcgtgccttc acgctttagc 600 ggctctggca gtggtacaga cttcactttt accatctctt cacttcagcc ggaggacatc 660 gccacatatt actgtcaaca gtacggaaac ttgcccttta cttttggagg cggcaccaaa 720 gttgaaatca aaagggccgc tgccctggat aacgaaaaga gcaatgggac tataatacat 780 gttaaaggaa aacacctgtg tccatctccc ctgttccctg gaccgtcaaa gccattttgg 840 gtgctcgtgg ttgtcggtgg cgttctcgcc tgttatagct tgctggtgac agtagccttc 900 attatctttt gggtgagatc caaaagaagc cgcctgctcc atagcgatta catgaatatg 960 actccacgcc gccctggccc cacaaggaaa cactaccagc cttacgcacc acctagagat 1020 ttcgctgcct atcggagcag ggtgaagttt tccagatctg cagatgcacc agcgtatcag 1080 cagggccaga accaactgta taacgagctc aacctgggac gcagggaaga gtatgacgtt 1140 ttggacaagc gcagaggacg ggaccctgag atgggtggca aaccaagacg aaaaaacccc 1200 caggagggtc tctataatga gctgcagaag gataagatgg ctgaagccta ttctgaaata 1260 ggcatgaaag gagagcggag aaggggaaaa gggcacgacg gtttgtacca gggactcagc 1320 actgctacga aggatactta tgacgctctc cacatgcaag ccctgccacc tagg 1374 <210> 28 <211> 458 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 28 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 20 25 30 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile 35 40 45 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu 65 70 75 80 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val 85 90 95 Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp 100 105 110 Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly 115 120 125 Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Leu Thr Gln Ser 130 135 140 Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Ser Phe Thr Cys 145 150 155 160 Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn Trp Tyr Gln Gln Lys 165 170 175 Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser Asn Leu Glu 180 185 190 Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe 195 200 205 Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr Tyr Tyr 210 215 220 Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe Gly Gly Gly Thr Lys 225 230 235 240 Val Glu Ile Lys Arg Ala Ala Ala Leu Asp Asn Glu Lys Ser Asn Gly 245 250 255 Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe 260 265 270 Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val 275 280 285 Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp 290 295 300 Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met 305 310 315 320 Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala 325 330 335 Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg 340 345 350 Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn 355 360 365 Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg 370 375 380 Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro 385 390 395 400 Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala 405 410 415 Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His 420 425 430 Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp 435 440 445 Ala Leu His Met Gln Ala Leu Pro Pro Arg 450 455 <210> 29 <211> 1467 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 29 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtgc agctgcagga atccggaccg gggctggtga agcccagcga gactctgagt 120 ctcacgtgta cagtttctgg aggtagcatt agctcctact attggtcatg gataaggcag 180 ccccccggga agggattgga atggatcggc tatatttact acagtgggag caccaattac 240 aacccctcac tgaagtctag agttacaatc agcgttgaca cctcaaagaa tcagttcagt 300 ttgaaattgt ctagcgtcac agcagctgat acagccgtct attattgtgt ttctctggtc 360 tattgcggtg gggattgtta cagtggcttt gactattggg ggcagggtac tctggttaca 420 gtttcttccg gggggggagg ctctgggggc ggaggctcag gtggtggagg cagcgacatc 480 cagttgacac agagcccgag ttccttgtcc gcctccgtcg gggatagagt gtcatttacc 540 tgtcaggcct ctcaggatat taataacttt ctgaattggt atcagcaaaa gcccggaaag 600 gcacccaagc tgttgattta cgacgccagt aacctggaga caggcgtgcc ctcccggttt 660 agtggtagcg gaagcggtac ggattttacc tttactatca gctctctcca acccgaagac 720 attgcaacct actattgtca acaatatgga aacctgcctt ttacatttgg cggcggcacc 780 aaggtggaga ttaagcgggc ggcagctatt gaggtgatgt atccaccgcc ttacctggat 840 aacgaaaaga gtaacggtac catcattcac gtgaaaggta aacacctgtg tccttctccc 900 ctcttccccg ggccatcaaa gcccttctgg gttcttgtgg tcgtgggagg cgtgcttgct 960 tgttattctc tgctcgttac cgtggcgttt atcatttttt gggttagatc caaaagaagc 1020 cgcctgctcc atagcgatta catgaatatg actccacgcc gccctggccc cacaaggaaa 1080 cactaccagc cttacgcacc acctagagat ttcgctgcct atcggagcag ggtgaagttt 1140 tccagatctg cagatgcacc agcgtatcag cagggccaga accaactgta taacgagctc 1200 aacctgggac gcagggaaga gtatgacgtt ttggacaagc gcagaggacg ggaccctgag 1260 atgggtggca aaccaagacg aaaaaacccc caggagggtc tctataatga gctgcagaag 1320 gataagatgg ctgaagccta ttctgaaata ggcatgaaag gagagcggag aaggggaaaa 1380 gggcacgacg gtttgtacca gggactcagc actgctacga aggatactta tgacgctctc 1440 cacatgcaag ccctgccacc taggtaa 1467 <210> 30 <211> 488 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 30 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu 20 25 30 Val Lys Pro Ser Glu Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly 35 40 45 Ser Ile Ser Ser Tyr Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys 50 55 60 Gly Leu Glu Trp Ile Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr 65 70 75 80 Asn Pro Ser Leu Lys Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys 85 90 95 Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 100 105 110 Val Tyr Tyr Cys Val Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser 115 120 125 Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly 130 135 140 Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile 145 150 155 160 Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg 165 170 175 Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn 180 185 190 Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp 195 200 205 Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly 210 215 220 Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp 225 230 235 240 Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe 245 250 255 Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Ile Glu Val 260 265 270 Met Tyr Pro Pro Pro Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile 275 280 285 Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly 290 295 300 Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala 305 310 315 320 Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg 325 330 335 Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro 340 345 350 Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro 355 360 365 Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala 370 375 380 Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu 385 390 395 400 Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly 405 410 415 Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu 420 425 430 Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser 435 440 445 Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly 450 455 460 Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu 465 470 475 480 His Met Gln Ala Leu Pro Pro Arg 485 <210> 31 <211> 1401 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 31 caggtgcagc tgcaggaatc cggaccgggg ctggtgaagc ccagcgagac tctgagtctc 60 acgtgtacag tttctggagg tagcattagc tcctactatt ggtcatggat aaggcagccc 120 cccgggaagg gattggaatg gatcggctat atttactaca gtgggagcac caattacaac 180 ccctcactga agtctagagt tacaatcagc gttgacacct caaagaatca gttcagtttg 240 aaattgtcta gcgtcacagc agctgataca gccgtctatt attgtgtttc tctggtctat 300 tgcggtgggg attgttacag tggctttgac tattgggggc agggtactct ggttacagtt 360 tcttccgggg ggggaggctc tgggggcgga ggctcaggtg gtggaggcag cgacatccag 420 ttgacacaga gcccgagttc cttgtccgcc tccgtcgggg atagagtgtc atttacctgt 480 caggcctctc aggatattaa taactttctg aattggtatc agcaaaagcc cggaaaggca 540 cccaagctgt tgatttacga cgccagtaac ctggagacag gcgtgccctc ccggtttagt 600 ggtagcggaa gcggtacgga ttttaccttt actatcagct ctctccaacc cgaagacatt 660 gcaacctact attgtcaaca atatggaaac ctgcctttta catttggcgg cggcaccaag 720 gtggagatta agcgggcggc agctattgag gtgatgtatc caccgcctta cctggataac 780 gaaaagagta acggtaccat cattcacgtg aaaggtaaac acctgtgtcc ttctcccctc 840 ttccccgggc catcaaagcc cttctgggtt cttgtggtcg tgggaggcgt gcttgcttgt 900 tattctctgc tcgttaccgt ggcgtttatc attttttggg ttagatccaa aagaagccgc 960 ctgctccata gcgattacat gaatatgact ccacgccgcc ctggccccac aaggaaacac 1020 taccagcctt acgcaccacc tagagatttc gctgcctatc ggagcagggt gaagttttcc 1080 agatctgcag atgcaccagc gtatcagcag ggccagaacc aactgtataa cgagctcaac 1140 ctgggacgca gggaagagta tgacgttttg gacaagcgca gaggacggga ccctgagatg 1200 ggtggcaaac caagacgaaa aaacccccag gagggtctct ataatgagct gcagaaggat 1260 aagatggctg aagcctattc tgaaataggc atgaaaggag agcggagaag gggaaaaggg 1320 cacgacggtt tgtaccaggg actcagcact gctacgaagg atacttatga cgctctccac 1380 atgcaagccc tgccacctag g 1401 <210> 32 <211> 467 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 32 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 20 25 30 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile 35 40 45 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu 65 70 75 80 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val 85 90 95 Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp 100 105 110 Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly 115 120 125 Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Leu Thr Gln Ser 130 135 140 Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Ser Phe Thr Cys 145 150 155 160 Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn Trp Tyr Gln Gln Lys 165 170 175 Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser Asn Leu Glu 180 185 190 Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe 195 200 205 Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr Tyr Tyr 210 215 220 Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe Gly Gly Gly Thr Lys 225 230 235 240 Val Glu Ile Lys Arg Ala Ala Ala Ile Glu Val Met Tyr Pro Pro Pro 245 250 255 Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly 260 265 270 Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe 275 280 285 Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu 290 295 300 Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg 305 310 315 320 Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro 325 330 335 Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala 340 345 350 Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr 355 360 365 Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg 370 375 380 Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met 385 390 395 400 Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu 405 410 415 Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys 420 425 430 Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu 435 440 445 Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu 450 455 460 Pro Pro Arg 465 <210> 33 <211> 1548 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 33 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtgc aattgcaaga gtccggcccc ggactcgtta aacccagtga gacgcttagc 120 ctgacctgta ccgtctcagg gggcagcatc tcctcttatt actggagctg gatcaggcag 180 cctccaggaa aaggccttga atggattggg tacatctact actctggctc aacaaattat 240 aatccatccc tgaagtcccg cgtgactatc tctgtggaca ccagcaagaa tcagttttca 300 ctgaagttgt ctagtgttac cgcggccgac accgccgtat actactgtgt gtctcttgtg 360 tactgtggcg gcgactgcta ttccgggttc gactactggg gccaagggac tctggtaacc 420 gtgtcctcag gcggcggcgg gtcaggagga ggcggcagtg gaggtggcgg ctccgacatc 480 cagctgacac aatcaccatc ttccctttca gcttcagtcg gggacagagt gtccttcaca 540 tgccaggcca gccaggatat caataacttc ctgaactggt accaacagaa acccggaaag 600 gctccaaagc tcctgatcta tgatgcttcc aacctggaga ccggcgtgcc ctccaggttc 660 agtggttcag gatcaggcac tgactttacg ttcaccatat ccagtcttca gcccgaagac 720 attgcaacct attactgcca acaatacggg aaccttccct ttacattcgg aggcggcacc 780 aaggtggaaa tcaaaagggc tgcagcattg agcaactcaa taatgtattt tagtcacttt 840 gtaccagtgt tcttgccggc taagcctact accacacccg ctccacggcc acctacccca 900 gctcctacca tcgcttcaca gcctctgtcc ctgcgcccag aggcttgccg accggccgca 960 gggggcgctg ttcataccag aggactggat ttcgcctgcg atatctatat ctgggcaccc 1020 ctggccggaa cctgcggcgt actcctgctg tccctggtca tcacgctcta ttgtaatcac 1080 aggaacagat ccaaaagaag ccgcctgctc catagcgatt acatgaatat gactccacgc 1140 cgccctggcc ccacaaggaa acactaccag ccttacgcac cacctagaga tttcgctgcc 1200 tatcggagca gggtgaagtt ttccagatct gcagatgcac cagcgtatca gcagggccag 1260 aaccaactgt ataacgagct caacctggga cgcagggaag agtatgacgt tttggacaag 1320 cgcagaggac gggaccctga gatgggtggc aaaccaagac gaaaaaaccc ccaggagggt 1380 ctctataatg agctgcagaa ggataagatg gctgaagcct attctgaaat aggcatgaaa 1440 ggagagcgga gaaggggaaa agggcacgac ggtttgtacc agggactcag cactgctacg 1500 aaggatactt atgacgctct ccacatgcaa gccctgccac ctaggtaa 1548 <210> 34 <211> 515 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 34 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu 20 25 30 Val Lys Pro Ser Glu Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly 35 40 45 Ser Ile Ser Ser Tyr Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys 50 55 60 Gly Leu Glu Trp Ile Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr 65 70 75 80 Asn Pro Ser Leu Lys Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys 85 90 95 Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 100 105 110 Val Tyr Tyr Cys Val Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser 115 120 125 Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly 130 135 140 Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile 145 150 155 160 Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg 165 170 175 Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn 180 185 190 Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp 195 200 205 Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly 210 215 220 Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp 225 230 235 240 Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe 245 250 255 Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Leu Ser Asn 260 265 270 Ser Ile Met Tyr Phe Ser His Phe Val Pro Val Phe Leu Pro Ala Lys 275 280 285 Pro Thr Thr Thr Pro Ala Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile 290 295 300 Ala Ser Gln Pro Leu Ser Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala 305 310 315 320 Gly Gly Ala Val His Thr Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr 325 330 335 Ile Trp Ala Pro Leu Ala Gly Thr Cys Gly Val Leu Leu Leu Ser Leu 340 345 350 Val Ile Thr Leu Tyr Cys Asn His Arg Asn Arg Ser Lys Arg Ser Arg 355 360 365 Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro 370 375 380 Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala 385 390 395 400 Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr 405 410 415 Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg 420 425 430 Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met 435 440 445 Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu 450 455 460 Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys 465 470 475 480 Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu 485 490 495 Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu 500 505 510 Pro Pro Arg 515 <210> 35 <211> 1482 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 35 caggtgcaat tgcaagagtc cggccccgga ctcgttaaac ccagtgagac gcttagcctg 60 acctgtaccg tctcaggggg cagcatctcc tcttattact ggagctggat caggcagcct 120 ccaggaaaag gccttgaatg gattgggtac atctactact ctggctcaac aaattataat 180 ccatccctga agtcccgcgt gactatctct gtggacacca gcaagaatca gttttcactg 240 aagttgtcta gtgttaccgc ggccgacacc gccgtatact actgtgtgtc tcttgtgtac 300 tgtggcggcg actgctattc cgggttcgac tactggggcc aagggactct ggtaaccgtg 360 tcctcaggcg gcggcgggtc aggaggaggc ggcagtggag gtggcggctc cgacatccag 420 ctgacacaat caccatcttc cctttcagct tcagtcgggg acagagtgtc cttcacatgc 480 caggccagcc aggatatcaa taacttcctg aactggtacc aacagaaacc cggaaaggct 540 ccaaagctcc tgatctatga tgcttccaac ctggagaccg gcgtgccctc caggttcagt 600 ggttcaggat caggcactga ctttacgttc accatatcca gtcttcagcc cgaagacatt 660 gcaacctatt actgccaaca atacgggaac cttcccttta cattcggagg cggcaccaag 720 gtggaaatca aaagggctgc agcattgagc aactcaataa tgtattttag tcactttgta 780 ccagtgttct tgccggctaa gcctactacc acacccgctc cacggccacc taccccagct 840 cctaccatcg cttcacagcc tctgtccctg cgcccagagg cttgccgacc ggccgcaggg 900 ggcgctgttc ataccagagg actggatttc gcctgcgata tctatatctg ggcacccctg 960 gccggaacct gcggcgtact cctgctgtcc ctggtcatca cgctctattg taatcacagg 1020 aacagatcca aaagaagccg cctgctccat agcgattaca tgaatatgac tccacgccgc 1080 cctggcccca caaggaaaca ctaccagcct tacgcaccac ctagagattt cgctgcctat 1140 cggagcaggg tgaagttttc cagatctgca gatgcaccag cgtatcagca gggccagaac 1200 caactgtata acgagctcaa cctgggacgc agggaagagt atgacgtttt ggacaagcgc 1260 agaggacggg accctgagat gggtggcaaa ccaagacgaa aaaaccccca ggagggtctc 1320 tataatgagc tgcagaagga taagatggct gaagcctatt ctgaaatagg catgaaagga 1380 gagcggagaa ggggaaaagg gcacgacggt ttgtaccagg gactcagcac tgctacgaag 1440 gatacttatg acgctctcca catgcaagcc ctgccaccta gg 1482 <210> 36 <211> 494 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 36 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 20 25 30 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile 35 40 45 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu 65 70 75 80 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val 85 90 95 Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp 100 105 110 Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly 115 120 125 Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Leu Thr Gln Ser 130 135 140 Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Ser Phe Thr Cys 145 150 155 160 Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn Trp Tyr Gln Gln Lys 165 170 175 Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser Asn Leu Glu 180 185 190 Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe 195 200 205 Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr Tyr Tyr 210 215 220 Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe Gly Gly Gly Thr Lys 225 230 235 240 Val Glu Ile Lys Arg Ala Ala Ala Leu Ser Asn Ser Ile Met Tyr Phe 245 250 255 Ser His Phe Val Pro Val Phe Leu Pro Ala Lys Pro Thr Thr Thr Pro 260 265 270 Ala Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile Ala Ser Gln Pro Leu 275 280 285 Ser Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala Gly Gly Ala Val His 290 295 300 Thr Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr Ile Trp Ala Pro Leu 305 310 315 320 Ala Gly Thr Cys Gly Val Leu Leu Leu Ser Leu Val Ile Thr Leu Tyr 325 330 335 Cys Asn His Arg Asn Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp 340 345 350 Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr 355 360 365 Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val 370 375 380 Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn 385 390 395 400 Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val 405 410 415 Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg 420 425 430 Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys 435 440 445 Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg 450 455 460 Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys 465 470 475 480 Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 485 490 <210> 37 <211> 1440 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 37 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccggatatcc agctcacgca atccccctca agcttgagtg cctccgtggg cgaccgggtg 120 tccttcacat gtcaggcaag ccaagacata aataatttcc tgaattggta ccaacaaaaa 180 cccggcaagg ctcccaaact cctgatttat gatgcctcca atctggagac cggggtccct 240 tctagattca gcggaagtgg cagcggcaca gactttacat ttactatctc ttctctgcaa 300 ccagaggaca tcgccacata ctattgccag caatacggca atctgccctt caccttcgga 360 ggcggaacca aggtagaaat taaaaggggc ggtggaggct ccggaggggg gggctctggc 420 ggagggggct cccaagtaca attgcaggag tcagggcctg gactcgtgaa gccttcagaa 480 actttgtcac tgacatgtac agtgtccggc ggaagcattt ccagttacta ttggtcctgg 540 attagacagc cacccggcaa aggactggaa tggattggat atatctacta ctctggatct 600 acaaactata atcccagcct caaatccagg gtcactatta gtgtggatac atcaaagaat 660 cagttctcct tgaagctgag ctcagtcact gctgccgaca ccgcagtgta ctattgtgtg 720 agcctggtct actgcggcgg agattgctac agcggtttcg attactgggg ccagggcacc 780 ctggttaccg ttagttccgc ggctgctctt gataacgaga agtccaacgg tacgattatc 840 cacgttaagg gtaagcacct ttgccctagc ccgctgttcc caggccccag taagcccttt 900 tgggtcctcg ttgtggtagg tggggtactc gcctgctact ccctgctcgt cactgtcgca 960 ttcatcatct tctgggtcag atccaaaaga agccgcctgc tccatagcga ttacatgaat 1020 atgactccac gccgccctgg ccccacaagg aaacactacc agccttacgc accacctaga 1080 gatttcgctg cctatcggag cagggtgaag ttttccagat ctgcagatgc accagcgtat 1140 cagcagggcc agaaccaact gtataacgag ctcaacctgg gacgcaggga agagtatgac 1200 gttttggaca agcgcagagg acgggaccct gagatgggtg gcaaaccaag acgaaaaaac 1260 ccccaggagg gtctctataa tgagctgcag aaggataaga tggctgaagc ctattctgaa 1320 ataggcatga aaggagagcg gagaagggga aaagggcacg acggtttgta ccagggactc 1380 agcactgcta cgaaggatac ttatgacgct ctccacatgc aagccctgcc acctaggtaa 1440 <210> 38 <211> 458 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 38 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Gly Gly Gly Gly 100 105 110 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gln Val Gln Leu Gln 115 120 125 Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu Thr Leu Ser Leu Thr 130 135 140 Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr Tyr Trp Ser Trp Ile 145 150 155 160 Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile Gly Tyr Ile Tyr Tyr 165 170 175 Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys Ser Arg Val Thr Ile 180 185 190 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 195 200 205 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val Ser Leu Val Tyr Cys 210 215 220 Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu 225 230 235 240 Val Thr Val Ser Ser Ala Ala Ala Leu Asp Asn Glu Lys Ser Asn Gly 245 250 255 Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe 260 265 270 Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val 275 280 285 Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp 290 295 300 Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met 305 310 315 320 Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala 325 330 335 Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg 340 345 350 Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn 355 360 365 Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg 370 375 380 Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro 385 390 395 400 Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala 405 410 415 Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His 420 425 430 Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp 435 440 445 Ala Leu His Met Gln Ala Leu Pro Pro Arg 450 455 <210> 39 <211> 1374 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 39 gatatccagc tcacgcaatc cccctcaagc ttgagtgcct ccgtgggcga ccgggtgtcc 60 ttcacatgtc aggcaagcca agacataaat aatttcctga attggtacca acaaaaaccc 120 ggcaaggctc ccaaactcct gatttatgat gcctccaatc tggagaccgg ggtcccttct 180 agattcagcg gaagtggcag cggcacagac tttacattta ctatctcttc tctgcaacca 240 gaggacatcg ccacatacta ttgccagcaa tacggcaatc tgcccttcac cttcggaggc 300 ggaaccaagg tagaaattaa aaggggcggt ggaggctccg gagggggggg ctctggcgga 360 gggggctccc aagtacaatt gcaggagtca gggcctggac tcgtgaagcc ttcagaaact 420 ttgtcactga catgtacagt gtccggcgga agcatttcca gttactattg gtcctggatt 480 agacagccac ccggcaaagg actggaatgg attggatata tctactactc tggatctaca 540 aactataatc ccagcctcaa atccagggtc actattagtg tggatacatc aaagaatcag 600 ttctccttga agctgagctc agtcactgct gccgacaccg cagtgtacta ttgtgtgagc 660 ctggtctact gcggcggaga ttgctacagc ggtttcgatt actggggcca gggcaccctg 720 gttaccgtta gttccgcggc tgctcttgat aacgagaagt ccaacggtac gattatccac 780 gttaagggta agcacctttg ccctagcccg ctgttcccag gccccagtaa gcccttttgg 840 gtcctcgttg tggtaggtgg ggtactcgcc tgctactccc tgctcgtcac tgtcgcattc 900 atcatcttct gggtcagatc caaaagaagc cgcctgctcc atagcgatta catgaatatg 960 actccacgcc gccctggccc cacaaggaaa cactaccagc cttacgcacc acctagagat 1020 ttcgctgcct atcggagcag ggtgaagttt tccagatctg cagatgcacc agcgtatcag 1080 cagggccaga accaactgta taacgagctc aacctgggac gcagggaaga gtatgacgtt 1140 ttggacaagc gcagaggacg ggaccctgag atgggtggca aaccaagacg aaaaaacccc 1200 caggagggtc tctataatga gctgcagaag gataagatgg ctgaagccta ttctgaaata 1260 ggcatgaaag gagagcggag aaggggaaaa gggcacgacg gtttgtacca gggactcagc 1320 actgctacga aggatactta tgacgctctc cacatgcaag ccctgccacc tagg 1374 <210> 40 <211> 458 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 40 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Gly Gly Gly Gly 100 105 110 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gln Val Gln Leu Gln 115 120 125 Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu Thr Leu Ser Leu Thr 130 135 140 Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr Tyr Trp Ser Trp Ile 145 150 155 160 Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile Gly Tyr Ile Tyr Tyr 165 170 175 Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys Ser Arg Val Thr Ile 180 185 190 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 195 200 205 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val Ser Leu Val Tyr Cys 210 215 220 Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu 225 230 235 240 Val Thr Val Ser Ser Ala Ala Ala Leu Asp Asn Glu Lys Ser Asn Gly 245 250 255 Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe 260 265 270 Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val 275 280 285 Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp 290 295 300 Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met 305 310 315 320 Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala 325 330 335 Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg 340 345 350 Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn 355 360 365 Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg 370 375 380 Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro 385 390 395 400 Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala 405 410 415 Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His 420 425 430 Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp 435 440 445 Ala Leu His Met Gln Ala Leu Pro Pro Arg 450 455 <210> 41 <211> 1467 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 41 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccggatatcc agctgaccca gtctccatcc tctttgagtg cctccgtggg tgaccgcgtc 120 tctttcactt gccaagccag ccaagacatc aacaactttc tgaattggta ccagcagaaa 180 ccaggcaaag caccaaagct cctcatctac gacgcctcca acctggaaac cggggtgccc 240 agcaggttta gcgggagcgg ttctggcacg gattttacgt tcaccatctc ctctctgcag 300 cccgaggata tagctactta ttactgtcag cagtacggga atctgccatt tacttttggg 360 ggtggaacta aggtggaaat caaaaggggc ggcgggggaa gcgggggcgg gggctcaggt 420 ggcggaggga gccaggtgca actccaggaa agtggcccag gattggtgaa gcccagcgag 480 accctttccc ttacttgtac tgttagcgga ggcagcataa gcagctacta ttggtcctgg 540 atcagacagc caccagggaa agggcttgaa tggattggct acatttacta ttccgggtcc 600 accaactaca acccatccct caagtcccgc gtgacaattt ccgtcgacac aagcaagaac 660 cagttctccc tgaaacttag tagcgtcact gctgcagata cagcagtgta ctattgtgtc 720 agccttgtct actgtggcgg cgactgctac agtggctttg attactgggg acagggcacg 780 ctcgtgacag tgtccagcgc tgcggctatc gaggtaatgt atccgccacc gtatctggac 840 aacgagaagt ctaatgggac aatcattcac gtgaagggga agcacctgtg tccatccccc 900 ctgtttccgg gtcccagtaa acccttctgg gtgcttgttg tcgttggcgg ggtgctggcc 960 tgctattccc tgctggtgac cgtcgcgttt attattttct gggttagatc caaaagaagc 1020 cgcctgctcc atagcgatta catgaatatg actccacgcc gccctggccc cacaaggaaa 1080 cactaccagc cttacgcacc acctagagat ttcgctgcct atcggagcag ggtgaagttt 1140 tccagatctg cagatgcacc agcgtatcag cagggccaga accaactgta taacgagctc 1200 aacctgggac gcagggaaga gtatgacgtt ttggacaagc gcagaggacg ggaccctgag 1260 atgggtggca aaccaagacg aaaaaacccc caggagggtc tctataatga gctgcagaag 1320 gataagatgg ctgaagccta ttctgaaata ggcatgaaag gagagcggag aaggggaaaa 1380 gggcacgacg gtttgtacca gggactcagc actgctacga aggatactta tgacgctctc 1440 cacatgcaag ccctgccacc taggtaa 1467 <210> 42 <211> 488 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 42 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu 20 25 30 Ser Ala Ser Val Gly Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln 35 40 45 Asp Ile Asn Asn Phe Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala 50 55 60 Pro Lys Leu Leu Ile Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro 65 70 75 80 Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile 85 90 95 Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr 100 105 110 Gly Asn Leu Pro Phe Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 115 120 125 Arg Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 130 135 140 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 145 150 155 160 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 165 170 175 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile 180 185 190 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 195 200 205 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu 210 215 220 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val 225 230 235 240 Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp 245 250 255 Gly Gln Gly Thr Leu Val Thr Val Ser Ser Ala Ala Ala Ile Glu Val 260 265 270 Met Tyr Pro Pro Pro Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile 275 280 285 Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly 290 295 300 Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala 305 310 315 320 Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg 325 330 335 Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro 340 345 350 Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro 355 360 365 Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala 370 375 380 Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu 385 390 395 400 Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly 405 410 415 Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu 420 425 430 Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser 435 440 445 Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly 450 455 460 Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu 465 470 475 480 His Met Gln Ala Leu Pro Pro Arg 485 <210> 43 <211> 1401 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 43 gatatccagc tgacccagtc tccatcctct ttgagtgcct ccgtgggtga ccgcgtctct 60 ttcacttgcc aagccagcca agacatcaac aactttctga attggtacca gcagaaacca 120 ggcaaagcac caaagctcct catctacgac gcctccaacc tggaaaccgg ggtgcccagc 180 aggtttagcg ggagcggttc tggcacggat tttacgttca ccatctcctc tctgcagccc 240 gaggatatag ctacttatta ctgtcagcag tacgggaatc tgccatttac ttttgggggt 300 ggaactaagg tggaaatcaa aaggggcggc gggggaagcg ggggcggggg ctcaggtggc 360 ggagggagcc aggtgcaact ccaggaaagt ggcccaggat tggtgaagcc cagcgagacc 420 ctttccctta cttgtactgt tagcggaggc agcataagca gctactattg gtcctggatc 480 agacagccac cagggaaagg gcttgaatgg attggctaca tttactattc cgggtccacc 540 aactacaacc catccctcaa gtcccgcgtg acaatttccg tcgacacaag caagaaccag 600 ttctccctga aacttagtag cgtcactgct gcagatacag cagtgtacta ttgtgtcagc 660 cttgtctact gtggcggcga ctgctacagt ggctttgatt actggggaca gggcacgctc 720 gtgacagtgt ccagcgctgc ggctatcgag gtaatgtatc cgccaccgta tctggacaac 780 gagaagtcta atgggacaat cattcacgtg aaggggaagc acctgtgtcc atcccccctg 840 tttccgggtc ccagtaaacc cttctgggtg cttgttgtcg ttggcggggt gctggcctgc 900 tattccctgc tggtgaccgt cgcgtttatt attttctggg ttagatccaa aagaagccgc 960 ctgctccata gcgattacat gaatatgact ccacgccgcc ctggccccac aaggaaacac 1020 taccagcctt acgcaccacc tagagatttc gctgcctatc ggagcagggt gaagttttcc 1080 agatctgcag atgcaccagc gtatcagcag ggccagaacc aactgtataa cgagctcaac 1140 ctgggacgca gggaagagta tgacgttttg gacaagcgca gaggacggga ccctgagatg 1200 ggtggcaaac caagacgaaa aaacccccag gagggtctct ataatgagct gcagaaggat 1260 aagatggctg aagcctattc tgaaataggc atgaaaggag agcggagaag gggaaaaggg 1320 cacgacggtt tgtaccaggg actcagcact gctacgaagg atacttatga cgctctccac 1380 atgcaagccc tgccacctag g 1401 <210> 44 <211> 467 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 44 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Gly Gly Gly Gly 100 105 110 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gln Val Gln Leu Gln 115 120 125 Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu Thr Leu Ser Leu Thr 130 135 140 Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr Tyr Trp Ser Trp Ile 145 150 155 160 Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile Gly Tyr Ile Tyr Tyr 165 170 175 Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys Ser Arg Val Thr Ile 180 185 190 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 195 200 205 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val Ser Leu Val Tyr Cys 210 215 220 Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu 225 230 235 240 Val Thr Val Ser Ser Ala Ala Ala Ile Glu Val Met Tyr Pro Pro Pro 245 250 255 Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly 260 265 270 Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe 275 280 285 Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu 290 295 300 Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg 305 310 315 320 Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro 325 330 335 Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala 340 345 350 Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr 355 360 365 Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg 370 375 380 Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met 385 390 395 400 Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu 405 410 415 Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys 420 425 430 Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu 435 440 445 Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu 450 455 460 Pro Pro Arg 465 <210> 45 <211> 1548 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 45 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccggacattc aattgaccca gtcccctagc agtctctcag caagtgtggg agatagggtg 120 tcattcacct gtcaggcttc acaggacatc aacaacttcc tcaattggta tcagcagaag 180 ccagggaagg caccaaagct gctcatatat gacgcttcaa accttgaaac cggagtacct 240 agccgcttca gcggaagcgg atcagggact gacttcactt ttaccatctc ttcactgcag 300 cccgaagaca tcgccacata ctactgccag cagtacggaa acttgccttt tacatttggg 360 ggcggcacca aagtggagat taagcgaggg ggaggcggct caggaggcgg tggctccgga 420 ggcgggggtt cccaggtcca gctccaggaa tccggcccag gtctggttaa gcccagtgaa 480 actttgtccc tcacgtgtac tgtgagcggt ggttcaatct cctcatacta ttggtcttgg 540 atacggcaac ctcctggaaa gggcctcgag tggatcggct atatctacta tagtggctcc 600 actaattaca acccttccct caagtccaga gtcaccattt ccgtggacac atctaagaac 660 cagttcagtc tgaagttgtc cagcgttaca gccgcagaca cagccgttta ttactgtgtg 720 tctcttgttt actgcggggg agactgttat agcggcttcg attactgggg ccagggcacc 780 ttggtcacag tctcttccgc ggccgccctc tctaacagta ttatgtactt ttctcatttt 840 gtacccgtgt tccttcccgc taagccaact actaccccgg ccccacggcc gcctacccct 900 gcacccacaa tagccagtca gcctttgagc ctgagacctg aggcttgtcg gccggctgct 960 gggggtgcag tgcacacacg aggtcttgat tttgcttgcg acatatacat ctgggcccct 1020 ctggccggga cctgtggggt gctgcttctg agcttggtca tcacgctcta ttgcaaccat 1080 cgcaacagat ccaaaagaag ccgcctgctc catagcgatt acatgaatat gactccacgc 1140 cgccctggcc ccacaaggaa acactaccag ccttacgcac cacctagaga tttcgctgcc 1200 tatcggagca gggtgaagtt ttccagatct gcagatgcac cagcgtatca gcagggccag 1260 aaccaactgt ataacgagct caacctggga cgcagggaag agtatgacgt tttggacaag 1320 cgcagaggac gggaccctga gatgggtggc aaaccaagac gaaaaaaccc ccaggagggt 1380 ctctataatg agctgcagaa ggataagatg gctgaagcct attctgaaat aggcatgaaa 1440 ggagagcgga gaaggggaaa agggcacgac ggtttgtacc agggactcag cactgctacg 1500 aaggatactt atgacgctct ccacatgcaa gccctgccac ctaggtaa 1548 <210> 46 <211> 515 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 46 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu 20 25 30 Ser Ala Ser Val Gly Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln 35 40 45 Asp Ile Asn Asn Phe Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala 50 55 60 Pro Lys Leu Leu Ile Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro 65 70 75 80 Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile 85 90 95 Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr 100 105 110 Gly Asn Leu Pro Phe Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 115 120 125 Arg Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 130 135 140 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 145 150 155 160 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 165 170 175 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile 180 185 190 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 195 200 205 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu 210 215 220 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val 225 230 235 240 Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp 245 250 255 Gly Gln Gly Thr Leu Val Thr Val Ser Ser Ala Ala Ala Leu Ser Asn 260 265 270 Ser Ile Met Tyr Phe Ser His Phe Val Pro Val Phe Leu Pro Ala Lys 275 280 285 Pro Thr Thr Thr Pro Ala Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile 290 295 300 Ala Ser Gln Pro Leu Ser Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala 305 310 315 320 Gly Gly Ala Val His Thr Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr 325 330 335 Ile Trp Ala Pro Leu Ala Gly Thr Cys Gly Val Leu Leu Leu Ser Leu 340 345 350 Val Ile Thr Leu Tyr Cys Asn His Arg Asn Arg Ser Lys Arg Ser Arg 355 360 365 Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro 370 375 380 Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala 385 390 395 400 Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr 405 410 415 Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg 420 425 430 Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met 435 440 445 Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu 450 455 460 Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys 465 470 475 480 Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu 485 490 495 Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu 500 505 510 Pro Pro Arg 515 <210> 47 <211> 1482 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 47 gacattcaat tgacccagtc ccctagcagt ctctcagcaa gtgtgggaga tagggtgtca 60 ttcacctgtc aggcttcaca ggacatcaac aacttcctca attggtatca gcagaagcca 120 gggaaggcac caaagctgct catatatgac gcttcaaacc ttgaaaccgg agtacctagc 180 cgcttcagcg gaagcggatc agggactgac ttcactttta ccatctcttc actgcagccc 240 gaagacatcg ccacatacta ctgccagcag tacggaaact tgccttttac atttgggggc 300 ggcaccaaag tggagattaa gcgaggggga ggcggctcag gaggcggtgg ctccggaggc 360 gggggttccc aggtccagct ccaggaatcc ggcccaggtc tggttaagcc cagtgaaact 420 ttgtccctca cgtgtactgt gagcggtggt tcaatctcct catactattg gtcttggata 480 cggcaacctc ctggaaaggg cctcgagtgg atcggctata tctactatag tggctccact 540 aattacaacc cttccctcaa gtccagagtc accatttccg tggacacatc taagaaccag 600 ttcagtctga agttgtccag cgttacagcc gcagacacag ccgtttatta ctgtgtgtct 660 cttgtttact gcgggggaga ctgttatagc ggcttcgatt actggggcca gggcaccttg 720 gtcacagtct cttccgcggc cgccctctct aacagtatta tgtacttttc tcattttgta 780 cccgtgttcc ttcccgctaa gccaactact accccggccc cacggccgcc tacccctgca 840 cccacaatag ccagtcagcc tttgagcctg agacctgagg cttgtcggcc ggctgctggg 900 ggtgcagtgc acacacgagg tcttgatttt gcttgcgaca tatacatctg ggcccctctg 960 gccgggacct gtggggtgct gcttctgagc ttggtcatca cgctctattg caaccatcgc 1020 aacagatcca aaagaagccg cctgctccat agcgattaca tgaatatgac tccacgccgc 1080 cctggcccca caaggaaaca ctaccagcct tacgcaccac ctagagattt cgctgcctat 1140 cggagcaggg tgaagttttc cagatctgca gatgcaccag cgtatcagca gggccagaac 1200 caactgtata acgagctcaa cctgggacgc agggaagagt atgacgtttt ggacaagcgc 1260 agaggacggg accctgagat gggtggcaaa ccaagacgaa aaaaccccca ggagggtctc 1320 tataatgagc tgcagaagga taagatggct gaagcctatt ctgaaatagg catgaaagga 1380 gagcggagaa ggggaaaagg gcacgacggt ttgtaccagg gactcagcac tgctacgaag 1440 gatacttatg acgctctcca catgcaagcc ctgccaccta gg 1482 <210> 48 <211> 494 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 48 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Gly Gly Gly Gly 100 105 110 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gln Val Gln Leu Gln 115 120 125 Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu Thr Leu Ser Leu Thr 130 135 140 Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr Tyr Trp Ser Trp Ile 145 150 155 160 Arg Gln Pro Pro Gly Lys Gly Leu Glu Trp Ile Gly Tyr Ile Tyr Tyr 165 170 175 Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys Ser Arg Val Thr Ile 180 185 190 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 195 200 205 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Val Ser Leu Val Tyr Cys 210 215 220 Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu 225 230 235 240 Val Thr Val Ser Ser Ala Ala Ala Leu Ser Asn Ser Ile Met Tyr Phe 245 250 255 Ser His Phe Val Pro Val Phe Leu Pro Ala Lys Pro Thr Thr Thr Pro 260 265 270 Ala Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile Ala Ser Gln Pro Leu 275 280 285 Ser Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala Gly Gly Ala Val His 290 295 300 Thr Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr Ile Trp Ala Pro Leu 305 310 315 320 Ala Gly Thr Cys Gly Val Leu Leu Leu Ser Leu Val Ile Thr Leu Tyr 325 330 335 Cys Asn His Arg Asn Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp 340 345 350 Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr 355 360 365 Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val 370 375 380 Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn 385 390 395 400 Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val 405 410 415 Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg 420 425 430 Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys 435 440 445 Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg 450 455 460 Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys 465 470 475 480 Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 485 490 <210> 49 <211> 372 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 49 caggtacagc tgcaggaatc tgggcccgga cttgtcaagc caagtcagac actttctctt 60 acatgtaccg tgagcggcgg aagtataagc agtggaggct tttactggtc ttggatacgg 120 cagcacccag gcaaaggctt ggagtggatt ggatacattc atcattcagg atctacacac 180 tataatccat cccttaagtc ccgggtcacc attagcattg atacgtctaa gaatctgttc 240 agtctcaggc tgtcctccgt cactgctgcc gacacagccg tgtactactg cgcctccttg 300 gtttactgcg gaggcgactg ttatagcggc tttgattatt gggggcaggg gaccctcgta 360 accgtgagct ct 372 <210> 50 <211> 124 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 50 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Gln 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Gly 20 25 30 Gly Phe Tyr Trp Ser Trp Ile Arg Gln His Pro Gly Lys Gly Leu Glu 35 40 45 Trp Ile Gly Tyr Ile His His Ser Gly Ser Thr His Tyr Asn Pro Ser 50 55 60 Leu Lys Ser Arg Val Thr Ile Ser Ile Asp Thr Ser Lys Asn Leu Phe 65 70 75 80 Ser Leu Arg Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 85 90 95 Cys Ala Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 51 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 51 Gly Gly Ser Ile Ser Ser Gly Gly Phe 1 5 <210> 52 <211> 5 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 52 His His Ser Gly Ser 1 5 <210> 53 <211> 14 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 53 Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp Tyr 1 5 10 <210> 54 <211> 324 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 54 gatatccagc tcactcaaag cccctctagt ctctctgcct cagtggggga tcgggtcagt 60 tttacttgtc aagcttcaca ggatatcaac aacttcctta attggtatca gcagaagcca 120 ggaaaagcac ccaagctgct catctatgat gcctcaaatt tggagacggg tgttcccagt 180 cgattctctg ggtcagggtc cgggaccgac tttacgttta cgatctcctc tctgcagccc 240 gaagacatcg ccacatacta ttgtcaacag tacggcaact tgcctttcac atttgggggc 300 gggactaagg ttgaaatcaa gagg 324 <210> 55 <211> 108 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 55 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 85 90 95 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg 100 105 <210> 56 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 56 Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn 1 5 10 <210> 57 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 57 Asp Ala Ser Asn Leu Glu Thr 1 5 <210> 58 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 58 Gln Gln Tyr Gly Asn Leu Pro Phe Thr 1 5 <210> 59 <211> 1446 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 59 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtac agctgcagga atctgggccc ggacttgtca agccaagtca gacactttct 120 cttacatgta ccgtgagcgg cggaagtata agcagtggag gcttttactg gtcttggata 180 cggcagcacc caggcaaagg cttggagtgg attggataca ttcatcattc aggatctaca 240 cactataatc catcccttaa gtcccgggtc accattagca ttgatacgtc taagaatctg 300 ttcagtctca ggctgtcctc cgtcactgct gccgacacag ccgtgtacta ctgcgcctcc 360 ttggtttact gcggaggcga ctgttatagc ggctttgatt attgggggca ggggaccctc 420 gtaaccgtga gctctggagg gggtgggagc gggggaggag gttcaggggg gggcggctcc 480 gatatccagc tcactcaaag cccctctagt ctctctgcct cagtggggga tcgggtcagt 540 tttacttgtc aagcttcaca ggatatcaac aacttcctta attggtatca gcagaagcca 600 ggaaaagcac ccaagctgct catctatgat gcctcaaatt tggagacggg tgttcccagt 660 cgattctctg ggtcagggtc cgggaccgac tttacgttta cgatctcctc tctgcagccc 720 gaagacatcg ccacatacta ttgtcaacag tacggcaact tgcctttcac atttgggggc 780 gggactaagg ttgaaatcaa gagggccgct gcactggaca atgagaagtc caacggcacc 840 atcatccacg tgaagggcaa gcacctgtgc cctagtcctc tgttcccagg cccatccaaa 900 cctttttggg ttcttgttgt ggtcgggggg gtgctggcct gctattctct gctggtcacg 960 gtggccttca taattttctg ggttagatcc aaaagaagcc gcctgctcca tagcgattac 1020 atgaatatga ctccacgccg ccctggcccc acaaggaaac actaccagcc ttacgcacca 1080 cctagagatt tcgctgccta tcggagcagg gtgaagtttt ccagatctgc agatgcacca 1140 gcgtatcagc agggccagaa ccaactgtat aacgagctca acctgggacg cagggaagag 1200 tatgacgttt tggacaagcg cagaggacgg gaccctgaga tgggtggcaa accaagacga 1260 aaaaaccccc aggagggtct ctataatgag ctgcagaagg ataagatggc tgaagcctat 1320 tctgaaatag gcatgaaagg agagcggaga aggggaaaag ggcacgacgg tttgtaccag 1380 ggactcagca ctgctacgaa ggatacttat gacgctctcc acatgcaagc cctgccacct 1440 aggtaa 1446 <210> 60 <211> 481 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 60 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu 20 25 30 Val Lys Pro Ser Gln Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly 35 40 45 Ser Ile Ser Ser Gly Gly Phe Tyr Trp Ser Trp Ile Arg Gln His Pro 50 55 60 Gly Lys Gly Leu Glu Trp Ile Gly Tyr Ile His His Ser Gly Ser Thr 65 70 75 80 His Tyr Asn Pro Ser Leu Lys Ser Arg Val Thr Ile Ser Ile Asp Thr 85 90 95 Ser Lys Asn Leu Phe Ser Leu Arg Leu Ser Ser Val Thr Ala Ala Asp 100 105 110 Thr Ala Val Tyr Tyr Cys Ala Ser Leu Val Tyr Cys Gly Gly Asp Cys 115 120 125 Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser 130 135 140 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 145 150 155 160 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 165 170 175 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 180 185 190 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 195 200 205 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 210 215 220 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 225 230 235 240 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 245 250 255 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Leu 260 265 270 Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly Lys His 275 280 285 Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe Trp Val 290 295 300 Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu Val Thr 305 310 315 320 Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg Leu Leu 325 330 335 His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg 340 345 350 Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg 355 360 365 Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln 370 375 380 Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu 385 390 395 400 Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly 405 410 415 Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln 420 425 430 Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu 435 440 445 Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr 450 455 460 Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro 465 470 475 480 Arg <210> 61 <211> 1380 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 61 caggtacagc tgcaggaatc tgggcccgga cttgtcaagc caagtcagac actttctctt 60 acatgtaccg tgagcggcgg aagtataagc agtggaggct tttactggtc ttggatacgg 120 cagcacccag gcaaaggctt ggagtggatt ggatacattc atcattcagg atctacacac 180 tataatccat cccttaagtc ccgggtcacc attagcattg atacgtctaa gaatctgttc 240 agtctcaggc tgtcctccgt cactgctgcc gacacagccg tgtactactg cgcctccttg 300 gtttactgcg gaggcgactg ttatagcggc tttgattatt gggggcaggg gaccctcgta 360 accgtgagct ctggaggggg tgggagcggg ggaggaggtt cagggggggg cggctccgat 420 atccagctca ctcaaagccc ctctagtctc tctgcctcag tgggggatcg ggtcagtttt 480 acttgtcaag cttcacagga tatcaacaac ttccttaatt ggtatcagca gaagccagga 540 aaagcaccca agctgctcat ctatgatgcc tcaaatttgg agacgggtgt tcccagtcga 600 ttctctgggt cagggtccgg gaccgacttt acgtttacga tctcctctct gcagcccgaa 660 gacatcgcca catactattg tcaacagtac ggcaacttgc ctttcacatt tgggggcggg 720 actaaggttg aaatcaagag ggccgctgca ctggacaatg agaagtccaa cggcaccatc 780 atccacgtga agggcaagca cctgtgccct agtcctctgt tcccaggccc atccaaacct 840 ttttgggttc ttgttgtggt cgggggggtg ctggcctgct attctctgct ggtcacggtg 900 gccttcataa ttttctgggt tagatccaaa agaagccgcc tgctccatag cgattacatg 960 aatatgactc cacgccgccc tggccccaca aggaaacact accagcctta cgcaccacct 1020 agagatttcg ctgcctatcg gagcagggtg aagttttcca gatctgcaga tgcaccagcg 1080 tatcagcagg gccagaacca actgtataac gagctcaacc tgggacgcag ggaagagtat 1140 gacgttttgg acaagcgcag aggacgggac cctgagatgg gtggcaaacc aagacgaaaa 1200 aacccccagg agggtctcta taatgagctg cagaaggata agatggctga agcctattct 1260 gaaataggca tgaaaggaga gcggagaagg ggaaaagggc acgacggttt gtaccaggga 1320 ctcagcactg ctacgaagga tacttatgac gctctccaca tgcaagccct gccacctagg 1380 <210> 62 <211> 460 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 62 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Gln 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Gly 20 25 30 Gly Phe Tyr Trp Ser Trp Ile Arg Gln His Pro Gly Lys Gly Leu Glu 35 40 45 Trp Ile Gly Tyr Ile His His Ser Gly Ser Thr His Tyr Asn Pro Ser 50 55 60 Leu Lys Ser Arg Val Thr Ile Ser Ile Asp Thr Ser Lys Asn Leu Phe 65 70 75 80 Ser Leu Arg Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 85 90 95 Cys Ala Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly 115 120 125 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Leu Thr 130 135 140 Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Ser Phe 145 150 155 160 Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn Trp Tyr Gln 165 170 175 Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser Asn 180 185 190 Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr 195 200 205 Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr 210 215 220 Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe Gly Gly Gly 225 230 235 240 Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Leu Asp Asn Glu Lys Ser 245 250 255 Asn Gly Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro 260 265 270 Leu Phe Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly 275 280 285 Gly Val Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile 290 295 300 Phe Trp Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met 305 310 315 320 Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro 325 330 335 Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe 340 345 350 Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu 355 360 365 Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp 370 375 380 Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys 385 390 395 400 Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala 405 410 415 Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys 420 425 430 Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr 435 440 445 Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 450 455 460 <210> 63 <211> 1473 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 63 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtgc agctgcagga aagcggtccg ggacttgtca agccgtccca aacgctgagt 120 ctgacgtgta ctgtctctgg tggctctatt tcttccgggg gcttttattg gtcttggatc 180 agacaacacc ctggcaaagg gctggagtgg atagggtata ttcaccactc tgggtccact 240 cactacaacc catcattgaa atccagagtg actatctcaa tcgacacatc caagaacctt 300 ttcagcctga ggttgtcatc agttaccgcc gctgacaccg cggtgtatta ttgcgcctct 360 ctcgtgtact gcggtggcga ttgttatagt ggctttgact actgggggca ggggacattg 420 gttaccgttt caagtggagg cggtgggtct ggcgggggcg gtagcggagg tggggggagc 480 gacatacagc ttacgcagag cccctccagc ctttcagcct ccgtggggga tagggtgtcc 540 tttacctgcc aggcttccca ggacataaac aacttcctca attggtatca gcaaaagccc 600 gggaaagcac caaagctgct catctacgat gccagcaacc tggaaaccgg agtgccgtct 660 cgcttctctg gaagtggcag tgggaccgat ttcactttta caatctcaag tttgcagcca 720 gaagacattg caacatacta ctgtcaacag tacggcaatc tcccctttac atttgggggg 780 ggaactaaag tggagattaa gcgcgctgca gccattgaag ttatgtatcc gcccccgtat 840 ctggataacg agaaatctaa tggtaccata atacatgtga aggggaagca cctctgtcca 900 tcaccgctgt tccccggccc ttcaaaacct ttctgggtac tcgttgtcgt gggtggagtt 960 ctggcctgct atagtctgct ggtgaccgtg gcgtttatca tcttctgggt aagatccaaa 1020 agaagccgcc tgctccatag cgattacatg aatatgactc cacgccgccc tggccccaca 1080 aggaaacact accagcctta cgcaccacct agagatttcg ctgcctatcg gagcagggtg 1140 aagttttcca gatctgcaga tgcaccagcg tatcagcagg gccagaacca actgtataac 1200 gagctcaacc tgggacgcag ggaagagtat gacgttttgg acaagcgcag aggacgggac 1260 cctgagatgg gtggcaaacc aagacgaaaa aacccccagg agggtctcta taatgagctg 1320 cagaaggata agatggctga agcctattct gaaataggca tgaaaggaga gcggagaagg 1380 ggaaaagggc acgacggttt gtaccaggga ctcagcactg ctacgaagga tacttatgac 1440 gctctccaca tgcaagccct gccacctagg taa 1473 <210> 64 <211> 490 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 64 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu 20 25 30 Val Lys Pro Ser Gln Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly 35 40 45 Ser Ile Ser Ser Gly Gly Phe Tyr Trp Ser Trp Ile Arg Gln His Pro 50 55 60 Gly Lys Gly Leu Glu Trp Ile Gly Tyr Ile His His Ser Gly Ser Thr 65 70 75 80 His Tyr Asn Pro Ser Leu Lys Ser Arg Val Thr Ile Ser Ile Asp Thr 85 90 95 Ser Lys Asn Leu Phe Ser Leu Arg Leu Ser Ser Val Thr Ala Ala Asp 100 105 110 Thr Ala Val Tyr Tyr Cys Ala Ser Leu Val Tyr Cys Gly Gly Asp Cys 115 120 125 Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser 130 135 140 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 145 150 155 160 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 165 170 175 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 180 185 190 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 195 200 205 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 210 215 220 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 225 230 235 240 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 245 250 255 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Ile 260 265 270 Glu Val Met Tyr Pro Pro Pro Tyr Leu Asp Asn Glu Lys Ser Asn Gly 275 280 285 Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe 290 295 300 Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val 305 310 315 320 Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp 325 330 335 Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met 340 345 350 Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala 355 360 365 Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg 370 375 380 Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn 385 390 395 400 Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg 405 410 415 Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro 420 425 430 Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala 435 440 445 Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His 450 455 460 Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp 465 470 475 480 Ala Leu His Met Gln Ala Leu Pro Pro Arg 485 490 <210> 65 <211> 1407 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 65 caggtgcagc tgcaggaaag cggtccggga cttgtcaagc cgtcccaaac gctgagtctg 60 acgtgtactg tctctggtgg ctctatttct tccgggggct tttattggtc ttggatcaga 120 caacaccctg gcaaagggct ggagtggata gggtatattc accactctgg gtccactcac 180 tacaacccat cattgaaatc cagagtgact atctcaatcg acacatccaa gaaccttttc 240 agcctgaggt tgtcatcagt taccgccgct gacaccgcgg tgtattattg cgcctctctc 300 gtgtactgcg gtggcgattg ttatagtggc tttgactact gggggcaggg gacattggtt 360 accgtttcaa gtggaggcgg tgggtctggc gggggcggta gcggaggtgg ggggagcgac 420 atacagctta cgcagagccc ctccagcctt tcagcctccg tgggggatag ggtgtccttt 480 acctgccagg cttcccagga cataaacaac ttcctcaatt ggtatcagca aaagcccggg 540 aaagcaccaa agctgctcat ctacgatgcc agcaacctgg aaaccggagt gccgtctcgc 600 ttctctggaa gtggcagtgg gaccgatttc acttttacaa tctcaagttt gcagccagaa 660 gacattgcaa catactactg tcaacagtac ggcaatctcc cctttacatt tgggggggga 720 actaaagtgg agattaagcg cgctgcagcc attgaagtta tgtatccgcc cccgtatctg 780 gataacgaga aatctaatgg taccataata catgtgaagg ggaagcacct ctgtccatca 840 ccgctgttcc ccggcccttc aaaacctttc tgggtactcg ttgtcgtggg tggagttctg 900 gcctgctata gtctgctggt gaccgtggcg tttatcatct tctgggtaag atccaaaaga 960 agccgcctgc tccatagcga ttacatgaat atgactccac gccgccctgg ccccacaagg 1020 aaacactacc agccttacgc accacctaga gatttcgctg cctatcggag cagggtgaag 1080 ttttccagat ctgcagatgc accagcgtat cagcagggcc agaaccaact gtataacgag 1140 ctcaacctgg gacgcaggga agagtatgac gttttggaca agcgcagagg acgggaccct 1200 gagatgggtg gcaaaccaag acgaaaaaac ccccaggagg gtctctataa tgagctgcag 1260 aaggataaga tggctgaagc ctattctgaa ataggcatga aaggagagcg gagaagggga 1320 aaagggcacg acggtttgta ccagggactc agcactgcta cgaaggatac ttatgacgct 1380 ctccacatgc aagccctgcc acctagg 1407 <210> 66 <211> 469 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 66 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Gln 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Gly 20 25 30 Gly Phe Tyr Trp Ser Trp Ile Arg Gln His Pro Gly Lys Gly Leu Glu 35 40 45 Trp Ile Gly Tyr Ile His His Ser Gly Ser Thr His Tyr Asn Pro Ser 50 55 60 Leu Lys Ser Arg Val Thr Ile Ser Ile Asp Thr Ser Lys Asn Leu Phe 65 70 75 80 Ser Leu Arg Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 85 90 95 Cys Ala Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly 115 120 125 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Leu Thr 130 135 140 Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Ser Phe 145 150 155 160 Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn Trp Tyr Gln 165 170 175 Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser Asn 180 185 190 Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr 195 200 205 Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr 210 215 220 Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe Gly Gly Gly 225 230 235 240 Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Ile Glu Val Met Tyr Pro 245 250 255 Pro Pro Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val 260 265 270 Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys 275 280 285 Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser 290 295 300 Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg 305 310 315 320 Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro 325 330 335 Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe 340 345 350 Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro 355 360 365 Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly 370 375 380 Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro 385 390 395 400 Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr 405 410 415 Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly 420 425 430 Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln 435 440 445 Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln 450 455 460 Ala Leu Pro Pro Arg 465 <210> 67 <211> 1554 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 67 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtgc agttgcagga aagcgggcct ggccttgtga aaccaagcca gacactgagc 120 ctgacatgca ctgtgtccgg cgggtccata tcttccgggg gtttttattg gtcctggata 180 cgccagcatc ccgggaaagg acttgaatgg attggatata tccaccattc cggaagcacc 240 cactacaatc caagccttaa atcccgggtg acaatctcca tcgacacctc aaagaatctt 300 ttttccctgc ggttgtcttc agtaactgcc gccgataccg ctgtgtacta ctgtgccagc 360 ctcgtctatt gcggcggaga ttgttattct gggttcgatt attggggtca aggcacactg 420 gtaactgtca gcagcggagg cggcggttcc gggggcgggg gcagtggagg gggcggatct 480 gacattcagc ttacgcagtc cccatcttca cttagcgcca gcgttggcga tcgggtcagc 540 ttcacgtgtc aagcaagtca ggatatcaac aactttctta actggtacca gcagaagcca 600 ggcaaggcac ccaagttgct gatttacgat gcttctaacc tcgagacggg agtgcctagc 660 cgcttctccg ggagcggcag cggcacagac tttaccttta cgatttccag tctgcagcca 720 gaggatatag caacttatta ctgtcagcag tatggcaacc tcccttttac cttcggtggt 780 ggcacaaagg tcgagattaa aagagccgca gcgttgtcca actccataat gtatttttct 840 cattttgtgc ccgtctttct gcctgccaaa cctaccacca cccccgcccc acgaccacct 900 actccagccc ccaccatcgc ctcccagccc ctcagcctga ggccagaggc ttgtcgccct 960 gctgcggggg gcgctgtcca taccagagga ctcgacttcg cctgcgatat ttatatatgg 1020 gcccccctcg ccggcacctg cggagtcttg ctcctgagcc ttgtgatcac gctttattgt 1080 aaccatcgga atagatccaa aagaagccgc ctgctccata gcgattacat gaatatgact 1140 ccacgccgcc ctggccccac aaggaaacac taccagcctt acgcaccacc tagagatttc 1200 gctgcctatc ggagcagggt gaagttttcc agatctgcag atgcaccagc gtatcagcag 1260 ggccagaacc aactgtataa cgagctcaac ctgggacgca gggaagagta tgacgttttg 1320 gacaagcgca gaggacggga ccctgagatg ggtggcaaac caagacgaaa aaacccccag 1380 gagggtctct ataatgagct gcagaaggat aagatggctg aagcctattc tgaaataggc 1440 atgaaaggag agcggagaag gggaaaaggg cacgacggtt tgtaccaggg actcagcact 1500 gctacgaagg atacttatga cgctctccac atgcaagccc tgccacctag gtaa 1554 <210> 68 <211> 517 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 68 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu 20 25 30 Val Lys Pro Ser Gln Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly 35 40 45 Ser Ile Ser Ser Gly Gly Phe Tyr Trp Ser Trp Ile Arg Gln His Pro 50 55 60 Gly Lys Gly Leu Glu Trp Ile Gly Tyr Ile His His Ser Gly Ser Thr 65 70 75 80 His Tyr Asn Pro Ser Leu Lys Ser Arg Val Thr Ile Ser Ile Asp Thr 85 90 95 Ser Lys Asn Leu Phe Ser Leu Arg Leu Ser Ser Val Thr Ala Ala Asp 100 105 110 Thr Ala Val Tyr Tyr Cys Ala Ser Leu Val Tyr Cys Gly Gly Asp Cys 115 120 125 Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser 130 135 140 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 145 150 155 160 Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 165 170 175 Asp Arg Val Ser Phe Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe 180 185 190 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 195 200 205 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 210 215 220 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 225 230 235 240 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe 245 250 255 Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Leu 260 265 270 Ser Asn Ser Ile Met Tyr Phe Ser His Phe Val Pro Val Phe Leu Pro 275 280 285 Ala Lys Pro Thr Thr Thr Pro Ala Pro Arg Pro Pro Thr Pro Ala Pro 290 295 300 Thr Ile Ala Ser Gln Pro Leu Ser Leu Arg Pro Glu Ala Cys Arg Pro 305 310 315 320 Ala Ala Gly Gly Ala Val His Thr Arg Gly Leu Asp Phe Ala Cys Asp 325 330 335 Ile Tyr Ile Trp Ala Pro Leu Ala Gly Thr Cys Gly Val Leu Leu Leu 340 345 350 Ser Leu Val Ile Thr Leu Tyr Cys Asn His Arg Asn Arg Ser Lys Arg 355 360 365 Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro 370 375 380 Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe 385 390 395 400 Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro 405 410 415 Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly 420 425 430 Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro 435 440 445 Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr 450 455 460 Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly 465 470 475 480 Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln 485 490 495 Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln 500 505 510 Ala Leu Pro Pro Arg 515 <210> 69 <211> 1488 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 69 caggtgcagt tgcaggaaag cgggcctggc cttgtgaaac caagccagac actgagcctg 60 acatgcactg tgtccggcgg gtccatatct tccgggggtt tttattggtc ctggatacgc 120 cagcatcccg ggaaaggact tgaatggatt ggatatatcc accattccgg aagcacccac 180 tacaatccaa gccttaaatc ccgggtgaca atctccatcg acacctcaaa gaatcttttt 240 tccctgcggt tgtcttcagt aactgccgcc gataccgctg tgtactactg tgccagcctc 300 gtctattgcg gcggagattg ttattctggg ttcgattatt ggggtcaagg cacactggta 360 actgtcagca gcggaggcgg cggttccggg ggcgggggca gtggaggggg cggatctgac 420 attcagctta cgcagtcccc atcttcactt agcgccagcg ttggcgatcg ggtcagcttc 480 acgtgtcaag caagtcagga tatcaacaac tttcttaact ggtaccagca gaagccaggc 540 aaggcaccca agttgctgat ttacgatgct tctaacctcg agacgggagt gcctagccgc 600 ttctccggga gcggcagcgg cacagacttt acctttacga tttccagtct gcagccagag 660 gatatagcaa cttattactg tcagcagtat ggcaacctcc cttttacctt cggtggtggc 720 acaaaggtcg agattaaaag agccgcagcg ttgtccaact ccataatgta tttttctcat 780 tttgtgcccg tctttctgcc tgccaaacct accaccaccc ccgccccacg accacctact 840 ccagccccca ccatcgcctc ccagcccctc agcctgaggc cagaggcttg tcgccctgct 900 gcggggggcg ctgtccatac cagaggactc gacttcgcct gcgatattta tatatgggcc 960 cccctcgccg gcacctgcgg agtcttgctc ctgagccttg tgatcacgct ttattgtaac 1020 catcggaata gatccaaaag aagccgcctg ctccatagcg attacatgaa tatgactcca 1080 cgccgccctg gccccacaag gaaacactac cagccttacg caccacctag agatttcgct 1140 gcctatcgga gcagggtgaa gttttccaga tctgcagatg caccagcgta tcagcagggc 1200 cagaaccaac tgtataacga gctcaacctg ggacgcaggg aagagtatga cgttttggac 1260 aagcgcagag gacgggaccc tgagatgggt ggcaaaccaa gacgaaaaaa cccccaggag 1320 ggtctctata atgagctgca gaaggataag atggctgaag cctattctga aataggcatg 1380 aaaggagagc ggagaagggg aaaagggcac gacggtttgt accagggact cagcactgct 1440 acgaaggata cttatgacgc tctccacatg caagccctgc cacctagg 1488 <210> 70 <211> 496 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 70 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Gln 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Gly 20 25 30 Gly Phe Tyr Trp Ser Trp Ile Arg Gln His Pro Gly Lys Gly Leu Glu 35 40 45 Trp Ile Gly Tyr Ile His His Ser Gly Ser Thr His Tyr Asn Pro Ser 50 55 60 Leu Lys Ser Arg Val Thr Ile Ser Ile Asp Thr Ser Lys Asn Leu Phe 65 70 75 80 Ser Leu Arg Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 85 90 95 Cys Ala Ser Leu Val Tyr Cys Gly Gly Asp Cys Tyr Ser Gly Phe Asp 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly 115 120 125 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Leu Thr 130 135 140 Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Ser Phe 145 150 155 160 Thr Cys Gln Ala Ser Gln Asp Ile Asn Asn Phe Leu Asn Trp Tyr Gln 165 170 175 Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser Asn 180 185 190 Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr 195 200 205 Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro Glu Asp Ile Ala Thr 210 215 220 Tyr Tyr Cys Gln Gln Tyr Gly Asn Leu Pro Phe Thr Phe Gly Gly Gly 225 230 235 240 Thr Lys Val Glu Ile Lys Arg Ala Ala Ala Leu Ser Asn Ser Ile Met 245 250 255 Tyr Phe Ser His Phe Val Pro Val Phe Leu Pro Ala Lys Pro Thr Thr 260 265 270 Thr Pro Ala Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile Ala Ser Gln 275 280 285 Pro Leu Ser Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala Gly Gly Ala 290 295 300 Val His Thr Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr Ile Trp Ala 305 310 315 320 Pro Leu Ala Gly Thr Cys Gly Val Leu Leu Leu Ser Leu Val Ile Thr 325 330 335 Leu Tyr Cys Asn His Arg Asn Arg Ser Lys Arg Ser Arg Leu Leu His 340 345 350 Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys 355 360 365 His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser 370 375 380 Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly 385 390 395 400 Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr 405 410 415 Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys 420 425 430 Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys 435 440 445 Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg 450 455 460 Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala 465 470 475 480 Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 485 490 495 <210> 71 <211> 363 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 71 caggtccaac tggtgcagtc cggagccgaa gtcaagaaac caggtgcctc cgttaaagtg 60 agttgcaaag tctctggata cactctgacc gagctctcta tgcactgggt ccggcaggcc 120 cccggcaagg gattggaatg gatgggcggg ttcgatcctg aggacggaga gactatctac 180 gctcaaaaat tccagggacg agtgactgtg accgaagaca ctagtaccga cactgcctac 240 atggaacttt cctctctgcg atcagaagat accgcagtgt actactgtgc tactgaatct 300 aggggcattg gatggcccta cttcgattac tggggtcagg gaactctggt gactgtctcc 360 agc 363 <210> 72 <211> 121 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 72 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Val Ser Gly Tyr Thr Leu Thr Glu Leu 20 25 30 Ser Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Met 35 40 45 Gly Gly Phe Asp Pro Glu Asp Gly Glu Thr Ile Tyr Ala Gln Lys Phe 50 55 60 Gln Gly Arg Val Thr Val Thr Glu Asp Thr Ser Thr Asp Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Thr Glu Ser Arg Gly Ile Gly Trp Pro Tyr Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 73 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 73 Gly Tyr Thr Leu Thr Glu Leu 1 5 <210> 74 <211> 6 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 74 Asp Pro Glu Asp Gly Glu 1 5 <210> 75 <211> 12 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 75 Glu Ser Arg Gly Ile Gly Trp Pro Tyr Phe Asp Tyr 1 5 10 <210> 76 <211> 324 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 76 gatattcaga tgactcaatc tccttcttct ctgtccgctt ccgtgggcga tagagtgacc 60 attacttgta gggcgtccca gtcaatctcc agttatttga attggtatca gcagaagccc 120 gggaaagcac ctaagctgtt gatcagcggg gcttctagcc tgaagagtgg ggtaccttca 180 cggttcagcg gaagcggaag cggaaccgat ttcaccctga ctatcagcag cctgccacct 240 gaggactttg caacttacta ctgccaacag tcatacagca ctccgatcac tttcggccag 300 ggcacccggc tcgaaatcaa gcgc 324 <210> 77 <211> 108 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 77 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Ser Ile Ser Ser Tyr 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Ser Gly Ala Ser Ser Leu Lys Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Pro Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln Ser Tyr Ser Thr Pro Ile 85 90 95 Thr Phe Gly Gln Gly Thr Arg Leu Glu Ile Lys Arg 100 105 <210> 78 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 78 Arg Ala Ser Gln Ser Ile Ser Ser Tyr Leu Asn 1 5 10 <210> 79 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 79 Gly Ala Ser Ser Leu Lys Ser 1 5 <210> 80 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 80 Gln Gln Ser Tyr Ser Thr Pro Ile Thr 1 5 <210> 81 <211> 1437 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 81 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtcc aactggtgca gtccggagcc gaagtcaaga aaccaggtgc ctccgttaaa 120 gtgagttgca aagtctctgg atacactctg accgagctct ctatgcactg ggtccggcag 180 gcccccggca agggattgga atggatgggc gggttcgatc ctgaggacgg agagactatc 240 tacgctcaaa aattccaggg acgagtgact gtgaccgaag acactagtac cgacactgcc 300 tacatggaac tttcctctct gcgatcagaa gataccgcag tgtactactg tgctactgaa 360 tctaggggca ttggatggcc ctacttcgat tactggggtc agggaactct ggtgactgtc 420 tccagcggtg gaggtggcag cggtggtggc ggaagcgggg ggggcggctc tgatattcag 480 atgactcaat ctccttcttc tctgtccgct tccgtgggcg atagagtgac cattacttgt 540 agggcgtccc agtcaatctc cagttatttg aattggtatc agcagaagcc cgggaaagca 600 cctaagctgt tgatcagcgg ggcttctagc ctgaagagtg gggtaccttc acggttcagc 660 ggaagcggaa gcggaaccga tttcaccctg actatcagca gcctgccacc tgaggacttt 720 gcaacttact actgccaaca gtcatacagc actccgatca ctttcggcca gggcacccgg 780 ctcgaaatca agcgcgctgc tgctttggac aatgagaagt caaacggcac catcatacat 840 gttaaaggta aacatctgtg tccctccccg ctgttccccg gcccttccaa accgttctgg 900 gttctggtgg tggtcggagg cgtactcgct tgctatagtc tgctggtaac tgtcgccttc 960 atcatctttt gggtgagatc caaaagaagc cgcctgctcc atagcgatta catgaatatg 1020 actccacgcc gccctggccc cacaaggaaa cactaccagc cttacgcacc acctagagat 1080 ttcgctgcct atcggagcag ggtgaagttt tccagatctg cagatgcacc agcgtatcag 1140 cagggccaga accaactgta taacgagctc aacctgggac gcagggaaga gtatgacgtt 1200 ttggacaagc gcagaggacg ggaccctgag atgggtggca aaccaagacg aaaaaacccc 1260 caggagggtc tctataatga gctgcagaag gataagatgg ctgaagccta ttctgaaata 1320 ggcatgaaag gagagcggag aaggggaaaa gggcacgacg gtttgtacca gggactcagc 1380 actgctacga aggatactta tgacgctctc cacatgcaag ccctgccacc taggtaa 1437 <210> 82 <211> 478 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 82 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val 20 25 30 Lys Lys Pro Gly Ala Ser Val Lys Val Ser Cys Lys Val Ser Gly Tyr 35 40 45 Thr Leu Thr Glu Leu Ser Met His Trp Val Arg Gln Ala Pro Gly Lys 50 55 60 Gly Leu Glu Trp Met Gly Gly Phe Asp Pro Glu Asp Gly Glu Thr Ile 65 70 75 80 Tyr Ala Gln Lys Phe Gln Gly Arg Val Thr Val Thr Glu Asp Thr Ser 85 90 95 Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 100 105 110 Ala Val Tyr Tyr Cys Ala Thr Glu Ser Arg Gly Ile Gly Trp Pro Tyr 115 120 125 Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly 130 135 140 Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln 145 150 155 160 Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val 165 170 175 Thr Ile Thr Cys Arg Ala Ser Gln Ser Ile Ser Ser Tyr Leu Asn Trp 180 185 190 Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Ser Gly Ala 195 200 205 Ser Ser Leu Lys Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser 210 215 220 Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Pro Pro Glu Asp Phe 225 230 235 240 Ala Thr Tyr Tyr Cys Gln Gln Ser Tyr Ser Thr Pro Ile Thr Phe Gly 245 250 255 Gln Gly Thr Arg Leu Glu Ile Lys Arg Ala Ala Ala Leu Asp Asn Glu 260 265 270 Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro 275 280 285 Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val 290 295 300 Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe 305 310 315 320 Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp 325 330 335 Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr 340 345 350 Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val 355 360 365 Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn 370 375 380 Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val 385 390 395 400 Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg 405 410 415 Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys 420 425 430 Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg 435 440 445 Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys 450 455 460 Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 465 470 475 <210> 83 <211> 1371 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 83 caggtccaac tggtgcagtc cggagccgaa gtcaagaaac caggtgcctc cgttaaagtg 60 agttgcaaag tctctggata cactctgacc gagctctcta tgcactgggt ccggcaggcc 120 cccggcaagg gattggaatg gatgggcggg ttcgatcctg aggacggaga gactatctac 180 gctcaaaaat tccagggacg agtgactgtg accgaagaca ctagtaccga cactgcctac 240 atggaacttt cctctctgcg atcagaagat accgcagtgt actactgtgc tactgaatct 300 aggggcattg gatggcccta cttcgattac tggggtcagg gaactctggt gactgtctcc 360 agcggtggag gtggcagcgg tggtggcgga agcggggggg gcggctctga tattcagatg 420 actcaatctc cttcttctct gtccgcttcc gtgggcgata gagtgaccat tacttgtagg 480 gcgtcccagt caatctccag ttatttgaat tggtatcagc agaagcccgg gaaagcacct 540 aagctgttga tcagcggggc ttctagcctg aagagtgggg taccttcacg gttcagcgga 600 agcggaagcg gaaccgattt caccctgact atcagcagcc tgccacctga ggactttgca 660 acttactact gccaacagtc atacagcact ccgatcactt tcggccaggg cacccggctc 720 gaaatcaagc gcgctgctgc tttggacaat gagaagtcaa acggcaccat catacatgtt 780 aaaggtaaac atctgtgtcc ctccccgctg ttccccggcc cttccaaacc gttctgggtt 840 ctggtggtgg tcggaggcgt actcgcttgc tatagtctgc tggtaactgt cgccttcatc 900 atcttttggg tgagatccaa aagaagccgc ctgctccata gcgattacat gaatatgact 960 ccacgccgcc ctggccccac aaggaaacac taccagcctt acgcaccacc tagagatttc 1020 gctgcctatc ggagcagggt gaagttttcc agatctgcag atgcaccagc gtatcagcag 1080 ggccagaacc aactgtataa cgagctcaac ctgggacgca gggaagagta tgacgttttg 1140 gacaagcgca gaggacggga ccctgagatg ggtggcaaac caagacgaaa aaacccccag 1200 gagggtctct ataatgagct gcagaaggat aagatggctg aagcctattc tgaaataggc 1260 atgaaaggag agcggagaag gggaaaaggg cacgacggtt tgtaccaggg actcagcact 1320 gctacgaagg atacttatga cgctctccac atgcaagccc tgccacctag g 1371 <210> 84 <211> 457 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 84 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Val Ser Gly Tyr Thr Leu Thr Glu Leu 20 25 30 Ser Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Met 35 40 45 Gly Gly Phe Asp Pro Glu Asp Gly Glu Thr Ile Tyr Ala Gln Lys Phe 50 55 60 Gln Gly Arg Val Thr Val Thr Glu Asp Thr Ser Thr Asp Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Thr Glu Ser Arg Gly Ile Gly Trp Pro Tyr Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly Gly 115 120 125 Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Met Thr Gln Ser Pro 130 135 140 Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr Cys Arg 145 150 155 160 Ala Ser Gln Ser Ile Ser Ser Tyr Leu Asn Trp Tyr Gln Gln Lys Pro 165 170 175 Gly Lys Ala Pro Lys Leu Leu Ile Ser Gly Ala Ser Ser Leu Lys Ser 180 185 190 Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr 195 200 205 Leu Thr Ile Ser Ser Leu Pro Pro Glu Asp Phe Ala Thr Tyr Tyr Cys 210 215 220 Gln Gln Ser Tyr Ser Thr Pro Ile Thr Phe Gly Gln Gly Thr Arg Leu 225 230 235 240 Glu Ile Lys Arg Ala Ala Ala Leu Asp Asn Glu Lys Ser Asn Gly Thr 245 250 255 Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro 260 265 270 Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu 275 280 285 Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val 290 295 300 Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr 305 310 315 320 Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro 325 330 335 Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser 340 345 350 Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu 355 360 365 Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg 370 375 380 Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln 385 390 395 400 Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr 405 410 415 Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp 420 425 430 Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala 435 440 445 Leu His Met Gln Ala Leu Pro Pro Arg 450 455 <210> 85 <211> 1464 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 85 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtgc agcttgtgca gagcggggcc gaggtgaaga agcccggggc cagcgtcaaa 120 gtgtcctgta aggtcagcgg ttacaccctc accgagctga gcatgcactg ggtacggcag 180 gctcccggca aaggtcttga gtggatgggt ggatttgatc cagaagatgg agagactatc 240 tacgcccaga agttccaggg ccgggtcacc gtaacagaag acacctcaac tgacaccgct 300 tacatggagc tgagttcact gcggtccgag gacacggccg tgtattattg tgccaccgag 360 agccgcggaa tcggatggcc ttacttcgac tactggggac agggtacact tgttacagta 420 tcatccgggg gtggcggctc tggtgggggc ggctccggag ggggtggatc agatatccaa 480 atgactcaaa gtccaagttc cctgtctgcc tcagtcggag atagagtcac cataacctgc 540 agggcaagtc agtccatctc ctcctatctg aactggtacc aacagaaacc tggaaaggcg 600 cctaagctcc tgatctccgg agcctcatct ttgaaatccg gtgtcccatc tcgcttcagt 660 ggctctggaa gcggtacaga ttttactttg accattagca gcctcccacc ggaagacttt 720 gctacatatt actgccagca gtcttactca accccaatca ccttcgggca aggcaccaga 780 ctcgaaataa aaagagcagc tgctatcgag gttatgtacc caccgccgta cttggataac 840 gaaaaaagca atgggaccat cattcatgtg aagggtaagc acctttgccc tagcccactg 900 tttcctggcc cgagtaaacc cttttgggta cttgtggtcg tcggcggcgt gctggcctgc 960 tactcactcc tggttaccgt cgcattcatc atcttttggg tgagatccaa aagaagccgc 1020 ctgctccata gcgattacat gaatatgact ccacgccgcc ctggccccac aaggaaacac 1080 taccagcctt acgcaccacc tagagatttc gctgcctatc ggagcagggt gaagttttcc 1140 agatctgcag atgcaccagc gtatcagcag ggccagaacc aactgtataa cgagctcaac 1200 ctgggacgca gggaagagta tgacgttttg gacaagcgca gaggacggga ccctgagatg 1260 ggtggcaaac caagacgaaa aaacccccag gagggtctct ataatgagct gcagaaggat 1320 aagatggctg aagcctattc tgaaataggc atgaaaggag agcggagaag gggaaaaggg 1380 cacgacggtt tgtaccaggg actcagcact gctacgaagg atacttatga cgctctccac 1440 atgcaagccc tgccacctag gtaa 1464 <210> 86 <211> 487 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 86 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val 20 25 30 Lys Lys Pro Gly Ala Ser Val Lys Val Ser Cys Lys Val Ser Gly Tyr 35 40 45 Thr Leu Thr Glu Leu Ser Met His Trp Val Arg Gln Ala Pro Gly Lys 50 55 60 Gly Leu Glu Trp Met Gly Gly Phe Asp Pro Glu Asp Gly Glu Thr Ile 65 70 75 80 Tyr Ala Gln Lys Phe Gln Gly Arg Val Thr Val Thr Glu Asp Thr Ser 85 90 95 Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 100 105 110 Ala Val Tyr Tyr Cys Ala Thr Glu Ser Arg Gly Ile Gly Trp Pro Tyr 115 120 125 Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly 130 135 140 Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln 145 150 155 160 Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val 165 170 175 Thr Ile Thr Cys Arg Ala Ser Gln Ser Ile Ser Ser Tyr Leu Asn Trp 180 185 190 Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Ser Gly Ala 195 200 205 Ser Ser Leu Lys Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser 210 215 220 Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Pro Pro Glu Asp Phe 225 230 235 240 Ala Thr Tyr Tyr Cys Gln Gln Ser Tyr Ser Thr Pro Ile Thr Phe Gly 245 250 255 Gln Gly Thr Arg Leu Glu Ile Lys Arg Ala Ala Ala Ile Glu Val Met 260 265 270 Tyr Pro Pro Pro Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile 275 280 285 His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro 290 295 300 Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys 305 310 315 320 Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser 325 330 335 Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg 340 345 350 Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg 355 360 365 Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp 370 375 380 Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn 385 390 395 400 Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg 405 410 415 Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly 420 425 430 Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu 435 440 445 Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu 450 455 460 Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His 465 470 475 480 Met Gln Ala Leu Pro Pro Arg 485 <210> 87 <211> 1398 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 87 caggtgcagc ttgtgcagag cggggccgag gtgaagaagc ccggggccag cgtcaaagtg 60 tcctgtaagg tcagcggtta caccctcacc gagctgagca tgcactgggt acggcaggct 120 cccggcaaag gtcttgagtg gatgggtgga tttgatccag aagatggaga gactatctac 180 gcccagaagt tccagggccg ggtcaccgta acagaagaca cctcaactga caccgcttac 240 atggagctga gttcactgcg gtccgaggac acggccgtgt attattgtgc caccgagagc 300 cgcggaatcg gatggcctta cttcgactac tggggacagg gtacacttgt tacagtatca 360 tccgggggtg gcggctctgg tgggggcggc tccggagggg gtggatcaga tatccaaatg 420 actcaaagtc caagttccct gtctgcctca gtcggagata gagtcaccat aacctgcagg 480 gcaagtcagt ccatctcctc ctatctgaac tggtaccaac agaaacctgg aaaggcgcct 540 aagctcctga tctccggagc ctcatctttg aaatccggtg tcccatctcg cttcagtggc 600 tctggaagcg gtacagattt tactttgacc attagcagcc tcccaccgga agactttgct 660 acatattact gccagcagtc ttactcaacc ccaatcacct tcgggcaagg caccagactc 720 gaaataaaaa gagcagctgc tatcgaggtt atgtacccac cgccgtactt ggataacgaa 780 aaaagcaatg ggaccatcat tcatgtgaag ggtaagcacc tttgccctag cccactgttt 840 cctggcccga gtaaaccctt ttgggtactt gtggtcgtcg gcggcgtgct ggcctgctac 900 tcactcctgg ttaccgtcgc attcatcatc ttttgggtga gatccaaaag aagccgcctg 960 ctccatagcg attacatgaa tatgactcca cgccgccctg gccccacaag gaaacactac 1020 cagccttacg caccacctag agatttcgct gcctatcgga gcagggtgaa gttttccaga 1080 tctgcagatg caccagcgta tcagcagggc cagaaccaac tgtataacga gctcaacctg 1140 ggacgcaggg aagagtatga cgttttggac aagcgcagag gacgggaccc tgagatgggt 1200 ggcaaaccaa gacgaaaaaa cccccaggag ggtctctata atgagctgca gaaggataag 1260 atggctgaag cctattctga aataggcatg aaaggagagc ggagaagggg aaaagggcac 1320 gacggtttgt accagggact cagcactgct acgaaggata cttatgacgc tctccacatg 1380 caagccctgc cacctagg 1398 <210> 88 <211> 466 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 88 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Val Ser Gly Tyr Thr Leu Thr Glu Leu 20 25 30 Ser Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Met 35 40 45 Gly Gly Phe Asp Pro Glu Asp Gly Glu Thr Ile Tyr Ala Gln Lys Phe 50 55 60 Gln Gly Arg Val Thr Val Thr Glu Asp Thr Ser Thr Asp Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Thr Glu Ser Arg Gly Ile Gly Trp Pro Tyr Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly Gly 115 120 125 Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Met Thr Gln Ser Pro 130 135 140 Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr Cys Arg 145 150 155 160 Ala Ser Gln Ser Ile Ser Ser Tyr Leu Asn Trp Tyr Gln Gln Lys Pro 165 170 175 Gly Lys Ala Pro Lys Leu Leu Ile Ser Gly Ala Ser Ser Leu Lys Ser 180 185 190 Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr 195 200 205 Leu Thr Ile Ser Ser Leu Pro Pro Glu Asp Phe Ala Thr Tyr Tyr Cys 210 215 220 Gln Gln Ser Tyr Ser Thr Pro Ile Thr Phe Gly Gln Gly Thr Arg Leu 225 230 235 240 Glu Ile Lys Arg Ala Ala Ala Ile Glu Val Met Tyr Pro Pro Pro Tyr 245 250 255 Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly Lys 260 265 270 His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe Trp 275 280 285 Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu Val 290 295 300 Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg Leu 305 310 315 320 Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr 325 330 335 Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr 340 345 350 Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln 355 360 365 Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu 370 375 380 Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly 385 390 395 400 Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu 405 410 415 Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly 420 425 430 Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser 435 440 445 Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro 450 455 460 Pro Arg 465 <210> 89 <211> 1545 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 89 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtgc agttggtgca aagcggcgca gaagttaaga aacctggggc gtcagttaag 120 gtgtcttgca aagtatctgg ctataccctc actgagctgt ccatgcattg ggtaaggcag 180 gctcctggaa aggggctcga atggatggga ggatttgacc ctgaagacgg agagaccatc 240 tacgcccaga aattccaggg tagagtaaca gtgactgagg acactagcac tgacacagcg 300 tacatggagc tgagttctct gagaagtgag gacacagccg tttactactg cgctaccgag 360 tccagaggta ttggctggcc atacttcgac tattggggtc agggcaccct ggttacagtg 420 agttcaggag gcgggggctc tggggggggc ggttccggag gggggggctc agatatacag 480 atgacgcaga gtccatcaag tctctcagcc agcgtgggag atcgcgtgac tattacttgc 540 cgcgccagcc agagtattag ctcctatctg aattggtacc agcaaaagcc cgggaaggcc 600 cctaagcttc tgatttctgg cgcctcctct ttgaagtcag gtgtgccaag cagatttagc 660 gggtctggaa gtggcactga ctttacactt actatctcca gcctgccccc agaggatttt 720 gccacatatt actgtcagca aagctactct actccaatca ctttcggcca gggcacaaga 780 ttggagatta agagggctgc cgcactttca aattccatca tgtatttcag ccattttgtg 840 cctgtttttc ttccggccaa acctacaacc actcccgccc cacgcccacc tactcccgcc 900 cctaccattg cctcccagcc tctgtctctt agacctgagg cttgtagacc tgctgccggc 960 ggagccgtgc acactcgcgg tctggacttc gcctgcgaca tctatatctg ggcccctctg 1020 gccggcacct gcggcgttct ccttctctca ctcgtaatca cactctattg caatcacagg 1080 aacagatcca aaagaagccg cctgctccat agcgattaca tgaatatgac tccacgccgc 1140 cctggcccca caaggaaaca ctaccagcct tacgcaccac ctagagattt cgctgcctat 1200 cggagcaggg tgaagttttc cagatctgca gatgcaccag cgtatcagca gggccagaac 1260 caactgtata acgagctcaa cctgggacgc agggaagagt atgacgtttt ggacaagcgc 1320 agaggacggg accctgagat gggtggcaaa ccaagacgaa aaaaccccca ggagggtctc 1380 tataatgagc tgcagaagga taagatggct gaagcctatt ctgaaatagg catgaaagga 1440 gagcggagaa ggggaaaagg gcacgacggt ttgtaccagg gactcagcac tgctacgaag 1500 gatacttatg acgctctcca catgcaagcc ctgccaccta ggtaa 1545 <210> 90 <211> 514 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 90 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val 20 25 30 Lys Lys Pro Gly Ala Ser Val Lys Val Ser Cys Lys Val Ser Gly Tyr 35 40 45 Thr Leu Thr Glu Leu Ser Met His Trp Val Arg Gln Ala Pro Gly Lys 50 55 60 Gly Leu Glu Trp Met Gly Gly Phe Asp Pro Glu Asp Gly Glu Thr Ile 65 70 75 80 Tyr Ala Gln Lys Phe Gln Gly Arg Val Thr Val Thr Glu Asp Thr Ser 85 90 95 Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 100 105 110 Ala Val Tyr Tyr Cys Ala Thr Glu Ser Arg Gly Ile Gly Trp Pro Tyr 115 120 125 Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly 130 135 140 Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln 145 150 155 160 Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val 165 170 175 Thr Ile Thr Cys Arg Ala Ser Gln Ser Ile Ser Ser Tyr Leu Asn Trp 180 185 190 Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Ser Gly Ala 195 200 205 Ser Ser Leu Lys Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser 210 215 220 Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Pro Pro Glu Asp Phe 225 230 235 240 Ala Thr Tyr Tyr Cys Gln Gln Ser Tyr Ser Thr Pro Ile Thr Phe Gly 245 250 255 Gln Gly Thr Arg Leu Glu Ile Lys Arg Ala Ala Ala Leu Ser Asn Ser 260 265 270 Ile Met Tyr Phe Ser His Phe Val Pro Val Phe Leu Pro Ala Lys Pro 275 280 285 Thr Thr Thr Pro Ala Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile Ala 290 295 300 Ser Gln Pro Leu Ser Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala Gly 305 310 315 320 Gly Ala Val His Thr Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr Ile 325 330 335 Trp Ala Pro Leu Ala Gly Thr Cys Gly Val Leu Leu Leu Ser Leu Val 340 345 350 Ile Thr Leu Tyr Cys Asn His Arg Asn Arg Ser Lys Arg Ser Arg Leu 355 360 365 Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr 370 375 380 Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr 385 390 395 400 Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln 405 410 415 Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu 420 425 430 Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly 435 440 445 Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu 450 455 460 Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly 465 470 475 480 Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser 485 490 495 Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro 500 505 510 Pro Arg <210> 91 <211> 1479 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 91 caggtgcagt tggtgcaaag cggcgcagaa gttaagaaac ctggggcgtc agttaaggtg 60 tcttgcaaag tatctggcta taccctcact gagctgtcca tgcattgggt aaggcaggct 120 cctggaaagg ggctcgaatg gatgggagga tttgaccctg aagacggaga gaccatctac 180 gcccagaaat tccagggtag agtaacagtg actgaggaca ctagcactga cacagcgtac 240 atggagctga gttctctgag aagtgaggac acagccgttt actactgcgc taccgagtcc 300 agaggtattg gctggccata cttcgactat tggggtcagg gcaccctggt tacagtgagt 360 tcaggaggcg ggggctctgg ggggggcggt tccggagggg ggggctcaga tatacagatg 420 acgcagagtc catcaagtct ctcagccagc gtgggagatc gcgtgactat tacttgccgc 480 gccagccaga gtattagctc ctatctgaat tggtaccagc aaaagcccgg gaaggcccct 540 aagcttctga tttctggcgc ctcctctttg aagtcaggtg tgccaagcag atttagcggg 600 tctggaagtg gcactgactt tacacttact atctccagcc tgcccccaga ggattttgcc 660 acatattact gtcagcaaag ctactctact ccaatcactt tcggccaggg cacaagattg 720 gagattaaga gggctgccgc actttcaaat tccatcatgt atttcagcca ttttgtgcct 780 gtttttcttc cggccaaacc tacaaccact cccgccccac gcccacctac tcccgcccct 840 accattgcct cccagcctct gtctcttaga cctgaggctt gtagacctgc tgccggcgga 900 gccgtgcaca ctcgcggtct ggacttcgcc tgcgacatct atatctgggc ccctctggcc 960 ggcacctgcg gcgttctcct tctctcactc gtaatcacac tctattgcaa tcacaggaac 1020 agatccaaaa gaagccgcct gctccatagc gattacatga atatgactcc acgccgccct 1080 ggccccacaa ggaaacacta ccagccttac gcaccaccta gagatttcgc tgcctatcgg 1140 agcagggtga agttttccag atctgcagat gcaccagcgt atcagcaggg ccagaaccaa 1200 ctgtataacg agctcaacct gggacgcagg gaagagtatg acgttttgga caagcgcaga 1260 ggacgggacc ctgagatggg tggcaaacca agacgaaaaa acccccagga gggtctctat 1320 aatgagctgc agaaggataa gatggctgaa gcctattctg aaataggcat gaaaggagag 1380 cggagaaggg gaaaagggca cgacggtttg taccagggac tcagcactgc tacgaaggat 1440 acttatgacg ctctccacat gcaagccctg ccacctagg 1479 <210> 92 <211> 493 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 92 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Val Ser Gly Tyr Thr Leu Thr Glu Leu 20 25 30 Ser Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Met 35 40 45 Gly Gly Phe Asp Pro Glu Asp Gly Glu Thr Ile Tyr Ala Gln Lys Phe 50 55 60 Gln Gly Arg Val Thr Val Thr Glu Asp Thr Ser Thr Asp Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Thr Glu Ser Arg Gly Ile Gly Trp Pro Tyr Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly Gly 115 120 125 Gly Gly Ser Gly Gly Gly Gly Ser Asp Ile Gln Met Thr Gln Ser Pro 130 135 140 Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr Cys Arg 145 150 155 160 Ala Ser Gln Ser Ile Ser Ser Tyr Leu Asn Trp Tyr Gln Gln Lys Pro 165 170 175 Gly Lys Ala Pro Lys Leu Leu Ile Ser Gly Ala Ser Ser Leu Lys Ser 180 185 190 Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr 195 200 205 Leu Thr Ile Ser Ser Leu Pro Pro Glu Asp Phe Ala Thr Tyr Tyr Cys 210 215 220 Gln Gln Ser Tyr Ser Thr Pro Ile Thr Phe Gly Gln Gly Thr Arg Leu 225 230 235 240 Glu Ile Lys Arg Ala Ala Ala Leu Ser Asn Ser Ile Met Tyr Phe Ser 245 250 255 His Phe Val Pro Val Phe Leu Pro Ala Lys Pro Thr Thr Thr Pro Ala 260 265 270 Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile Ala Ser Gln Pro Leu Ser 275 280 285 Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala Gly Gly Ala Val His Thr 290 295 300 Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr Ile Trp Ala Pro Leu Ala 305 310 315 320 Gly Thr Cys Gly Val Leu Leu Leu Ser Leu Val Ile Thr Leu Tyr Cys 325 330 335 Asn His Arg Asn Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr 340 345 350 Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln 355 360 365 Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys 370 375 380 Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln 385 390 395 400 Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu 405 410 415 Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg 420 425 430 Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met 435 440 445 Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly 450 455 460 Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp 465 470 475 480 Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 485 490 <210> 93 <211> 351 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 93 caggtccagt tggtcgaaag tggcggtggt gtagtgcagc cgggccgcag tttgaggctt 60 tcctgtgcgg cttcaggctt tactttttcc agctatggaa tgcactgggt gcggcaggcc 120 cccggcaaag gacttgagtg ggtggccgtc atttcttatg acggatcaga taagtactac 180 gtggacagcg tcaagggcag attcaccatc tctagggaca acagtaaaaa tagactctac 240 ctccagatga atagcctcag agctgaagac acggccgtct actattgtgc tcgggagcgg 300 tatagtggca gagactactg ggggcagggc acactcgtta cagtgagtag c 351 <210> 94 <211> 117 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 94 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu 100 105 110 Val Thr Val Ser Ser 115 <210> 95 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 95 Gly Phe Thr Phe Ser Ser Tyr 1 5 <210> 96 <211> 6 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 96 Ser Tyr Asp Gly Ser Asp 1 5 <210> 97 <211> 8 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 97 Glu Arg Tyr Ser Gly Arg Asp Tyr 1 5 <210> 98 <211> 324 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 98 gagattgtta tgacccagag tcctgcgacc ctctcagtca gccccgggga gcgcgcaact 60 ttgtcttgca gagctagtca gtccgtgtcc tctcttctga catggtacca gcaaaagccc 120 gggcaggctc cgcgcctttt gatctttggg gcttcaacaa gagccactgg gattcccgca 180 cgattctctg gctccgggag cggtactggt ttcaccctga cgattagcag tctccagagc 240 gaggacttcg ccgtatacta ctgccagcag tacgatacgt ggccattcac ttttggacca 300 gggactaaag tggattttaa gcgc 324 <210> 99 <211> 108 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 99 Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Leu 20 25 30 Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asp Thr Trp Pro Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys Arg 100 105 <210> 100 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 100 Arg Ala Ser Gln Ser Val Ser Ser Leu Leu Thr 1 5 10 <210> 101 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 101 Gly Ala Ser Thr Arg Ala Thr 1 5 <210> 102 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 102 Gln Gln Tyr Asp Thr Trp Pro Phe Thr 1 5 <210> 103 <211> 1425 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 103 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtcc agttggtcga aagtggcggt ggtgtagtgc agccgggccg cagtttgagg 120 ctttcctgtg cggcttcagg ctttactttt tccagctatg gaatgcactg ggtgcggcag 180 gcccccggca aaggacttga gtgggtggcc gtcatttctt atgacggatc agataagtac 240 tacgtggaca gcgtcaaggg cagattcacc atctctaggg acaacagtaa aaatagactc 300 tacctccaga tgaatagcct cagagctgaa gacacggccg tctactattg tgctcgggag 360 cggtatagtg gcagagacta ctgggggcag ggcacactcg ttacagtgag tagcggcgga 420 ggagggagtg ggggcggtgg ctccggtgga ggaggttctg agattgttat gacccagagt 480 cctgcgaccc tctcagtcag ccccggggag cgcgcaactt tgtcttgcag agctagtcag 540 tccgtgtcct ctcttctgac atggtaccag caaaagcccg ggcaggctcc gcgccttttg 600 atctttgggg cttcaacaag agccactggg attcccgcac gattctctgg ctccgggagc 660 ggtactggtt tcaccctgac gattagcagt ctccagagcg aggacttcgc cgtatactac 720 tgccagcagt acgatacgtg gccattcact tttggaccag ggactaaagt ggattttaag 780 cgcgccgccg ctctcgataa cgaaaagtca aatggcacca taatccacgt caaaggcaag 840 cacctgtgcc cttccccgct cttccccgga cccagtaaac cattttgggt gctggttgtt 900 gtggggggcg tgctggcctg ctatagcctt ttggtcactg tagccttcat tattttttgg 960 gtcagatcca aaagaagccg cctgctccat agcgattaca tgaatatgac tccacgccgc 1020 cctggcccca caaggaaaca ctaccagcct tacgcaccac ctagagattt cgctgcctat 1080 cggagcaggg tgaagttttc cagatctgca gatgcaccag cgtatcagca gggccagaac 1140 caactgtata acgagctcaa cctgggacgc agggaagagt atgacgtttt ggacaagcgc 1200 agaggacggg accctgagat gggtggcaaa ccaagacgaa aaaaccccca ggagggtctc 1260 tataatgagc tgcagaagga taagatggct gaagcctatt ctgaaatagg catgaaagga 1320 gagcggagaa ggggaaaagg gcacgacggt ttgtaccagg gactcagcac tgctacgaag 1380 gatacttatg acgctctcca catgcaagcc ctgccaccta ggtaa 1425 <210> 104 <211> 474 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 104 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val 20 25 30 Val Gln Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe 35 40 45 Thr Phe Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys 50 55 60 Gly Leu Glu Trp Val Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr 65 70 75 80 Tyr Val Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser 85 90 95 Lys Asn Arg Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 100 105 110 Ala Val Tyr Tyr Cys Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp 115 120 125 Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly 130 135 140 Gly Gly Gly Ser Gly Gly Gly Gly Ser Glu Ile Val Met Thr Gln Ser 145 150 155 160 Pro Ala Thr Leu Ser Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys 165 170 175 Arg Ala Ser Gln Ser Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys 180 185 190 Pro Gly Gln Ala Pro Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala 195 200 205 Thr Gly Ile Pro Ala Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe 210 215 220 Thr Leu Thr Ile Ser Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr 225 230 235 240 Cys Gln Gln Tyr Asp Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys 245 250 255 Val Asp Phe Lys Arg Ala Ala Ala Leu Asp Asn Glu Lys Ser Asn Gly 260 265 270 Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe 275 280 285 Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val 290 295 300 Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp 305 310 315 320 Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met 325 330 335 Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala 340 345 350 Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg 355 360 365 Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn 370 375 380 Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg 385 390 395 400 Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro 405 410 415 Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala 420 425 430 Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His 435 440 445 Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp 450 455 460 Ala Leu His Met Gln Ala Leu Pro Pro Arg 465 470 <210> 105 <211> 1359 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 105 caggtccagt tggtcgaaag tggcggtggt gtagtgcagc cgggccgcag tttgaggctt 60 tcctgtgcgg cttcaggctt tactttttcc agctatggaa tgcactgggt gcggcaggcc 120 cccggcaaag gacttgagtg ggtggccgtc atttcttatg acggatcaga taagtactac 180 gtggacagcg tcaagggcag attcaccatc tctagggaca acagtaaaaa tagactctac 240 ctccagatga atagcctcag agctgaagac acggccgtct actattgtgc tcgggagcgg 300 tatagtggca gagactactg ggggcagggc acactcgtta cagtgagtag cggcggagga 360 gggagtgggg gcggtggctc cggtggagga ggttctgaga ttgttatgac ccagagtcct 420 gcgaccctct cagtcagccc cggggagcgc gcaactttgt cttgcagagc tagtcagtcc 480 gtgtcctctc ttctgacatg gtaccagcaa aagcccgggc aggctccgcg ccttttgatc 540 tttggggctt caacaagagc cactgggatt cccgcacgat tctctggctc cgggagcggt 600 actggtttca ccctgacgat tagcagtctc cagagcgagg acttcgccgt atactactgc 660 cagcagtacg atacgtggcc attcactttt ggaccaggga ctaaagtgga ttttaagcgc 720 gccgccgctc tcgataacga aaagtcaaat ggcaccataa tccacgtcaa aggcaagcac 780 ctgtgccctt ccccgctctt ccccggaccc agtaaaccat tttgggtgct ggttgttgtg 840 gggggcgtgc tggcctgcta tagccttttg gtcactgtag ccttcattat tttttgggtc 900 agatccaaaa gaagccgcct gctccatagc gattacatga atatgactcc acgccgccct 960 ggccccacaa ggaaacacta ccagccttac gcaccaccta gagatttcgc tgcctatcgg 1020 agcagggtga agttttccag atctgcagat gcaccagcgt atcagcaggg ccagaaccaa 1080 ctgtataacg agctcaacct gggacgcagg gaagagtatg acgttttgga caagcgcaga 1140 ggacgggacc ctgagatggg tggcaaacca agacgaaaaa acccccagga gggtctctat 1200 aatgagctgc agaaggataa gatggctgaa gcctattctg aaataggcat gaaaggagag 1260 cggagaaggg gaaaagggca cgacggtttg taccagggac tcagcactgc tacgaaggat 1320 acttatgacg ctctccacat gcaagccctg ccacctagg 1359 <210> 106 <211> 453 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 106 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu 100 105 110 Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly 115 120 125 Gly Gly Gly Ser Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser 130 135 140 Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser 145 150 155 160 Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro 165 170 175 Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala 180 185 190 Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser 195 200 205 Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asp 210 215 220 Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys Arg 225 230 235 240 Ala Ala Ala Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val 245 250 255 Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys 260 265 270 Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser 275 280 285 Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg 290 295 300 Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro 305 310 315 320 Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe 325 330 335 Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro 340 345 350 Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly 355 360 365 Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro 370 375 380 Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr 385 390 395 400 Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly 405 410 415 Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln 420 425 430 Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln 435 440 445 Ala Leu Pro Pro Arg 450 <210> 107 <211> 1452 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 107 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtgc agctcgtgga gtctggcggc ggcgtggtcc agcccggccg gtccctgcgc 120 ctgtcctgcg ccgccagcgg gtttactttt tcctcctacg gcatgcactg ggtgcgccag 180 gctcccggca agggcctcga gtgggtcgcc gtgatctcat acgatgggtc agacaaatac 240 tatgtcgatt ctgttaaagg gcggtttacc atttcaagag ataactctaa gaataggctg 300 tatttgcaga tgaacagcct gagggctgaa gataccgcag tgtactattg cgctagggag 360 cggtatagtg gccgcgatta ctggggacag ggtacactgg tgaccgtgag ctctgggggt 420 ggcggaagcg ggggtggcgg aagcggcgga gggggtagtg aaattgtgat gacccagtct 480 ccggctacac tttcagtctc ccctggggag agagctacac tgtcatgcag agcgtcccag 540 tccgtctctt ctctccttac ctggtatcag cagaagcccg gccaggctcc tcgactgctg 600 atcttcggtg cctccacaag ggcgaccggg attccagccc gcttctcagg ttctgggagc 660 ggaactggtt tcactttgac aatcagttca ctgcagtcag aggatttcgc cgtgtactac 720 tgccagcaat acgacacatg gccattcact ttcggacccg gtaccaaagt cgatttcaag 780 agagccgcgg ccatcgaggt tatgtaccca ccaccatatc tggacaatga aaaaagcaat 840 ggaaccatta tccatgtgaa gggtaaacac ctctgcccta gcccactttt ccctggccca 900 tcaaagccct tctgggtctt ggtggtcgtg gggggtgtgc tggcctgtta cagccttctg 960 gtgacggttg ctttcattat cttctgggtt agatccaaaa gaagccgcct gctccatagc 1020 gattacatga atatgactcc acgccgccct ggccccacaa ggaaacacta ccagccttac 1080 gcaccaccta gagatttcgc tgcctatcgg agcagggtga agttttccag atctgcagat 1140 gcaccagcgt atcagcaggg ccagaaccaa ctgtataacg agctcaacct gggacgcagg 1200 gaagagtatg acgttttgga caagcgcaga ggacgggacc ctgagatggg tggcaaacca 1260 agacgaaaaa acccccagga gggtctctat aatgagctgc agaaggataa gatggctgaa 1320 gcctattctg aaataggcat gaaaggagag cggagaaggg gaaaagggca cgacggtttg 1380 taccagggac tcagcactgc tacgaaggat acttatgacg ctctccacat gcaagccctg 1440 ccacctaggt aa 1452 <210> 108 <211> 483 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 108 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val 20 25 30 Val Gln Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe 35 40 45 Thr Phe Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys 50 55 60 Gly Leu Glu Trp Val Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr 65 70 75 80 Tyr Val Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser 85 90 95 Lys Asn Arg Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 100 105 110 Ala Val Tyr Tyr Cys Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp 115 120 125 Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly 130 135 140 Gly Gly Gly Ser Gly Gly Gly Gly Ser Glu Ile Val Met Thr Gln Ser 145 150 155 160 Pro Ala Thr Leu Ser Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys 165 170 175 Arg Ala Ser Gln Ser Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys 180 185 190 Pro Gly Gln Ala Pro Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala 195 200 205 Thr Gly Ile Pro Ala Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe 210 215 220 Thr Leu Thr Ile Ser Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr 225 230 235 240 Cys Gln Gln Tyr Asp Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys 245 250 255 Val Asp Phe Lys Arg Ala Ala Ala Ile Glu Val Met Tyr Pro Pro Pro 260 265 270 Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly 275 280 285 Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe 290 295 300 Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu 305 310 315 320 Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg 325 330 335 Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro 340 345 350 Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala 355 360 365 Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr 370 375 380 Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg 385 390 395 400 Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met 405 410 415 Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu 420 425 430 Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys 435 440 445 Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu 450 455 460 Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu 465 470 475 480 Pro Pro Arg <210> 109 <211> 1386 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 109 caggtgcagc tcgtggagtc tggcggcggc gtggtccagc ccggccggtc cctgcgcctg 60 tcctgcgccg ccagcgggtt tactttttcc tcctacggca tgcactgggt gcgccaggct 120 cccggcaagg gcctcgagtg ggtcgccgtg atctcatacg atgggtcaga caaatactat 180 gtcgattctg ttaaagggcg gtttaccatt tcaagagata actctaagaa taggctgtat 240 ttgcagatga acagcctgag ggctgaagat accgcagtgt actattgcgc tagggagcgg 300 tatagtggcc gcgattactg gggacagggt acactggtga ccgtgagctc tgggggtggc 360 ggaagcgggg gtggcggaag cggcggaggg ggtagtgaaa ttgtgatgac ccagtctccg 420 gctacacttt cagtctcccc tggggagaga gctacactgt catgcagagc gtcccagtcc 480 gtctcttctc tccttacctg gtatcagcag aagcccggcc aggctcctcg actgctgatc 540 ttcggtgcct ccacaagggc gaccgggatt ccagcccgct tctcaggttc tgggagcgga 600 actggtttca ctttgacaat cagttcactg cagtcagagg atttcgccgt gtactactgc 660 cagcaatacg acacatggcc attcactttc ggacccggta ccaaagtcga tttcaagaga 720 gccgcggcca tcgaggttat gtacccacca ccatatctgg acaatgaaaa aagcaatgga 780 accattatcc atgtgaaggg taaacacctc tgccctagcc cacttttccc tggcccatca 840 aagcccttct gggtcttggt ggtcgtgggg ggtgtgctgg cctgttacag ccttctggtg 900 acggttgctt tcattatctt ctgggttaga tccaaaagaa gccgcctgct ccatagcgat 960 tacatgaata tgactccacg ccgccctggc cccacaagga aacactacca gccttacgca 1020 ccacctagag atttcgctgc ctatcggagc agggtgaagt tttccagatc tgcagatgca 1080 ccagcgtatc agcagggcca gaaccaactg tataacgagc tcaacctggg acgcagggaa 1140 gagtatgacg ttttggacaa gcgcagagga cgggaccctg agatgggtgg caaaccaaga 1200 cgaaaaaacc cccaggaggg tctctataat gagctgcaga aggataagat ggctgaagcc 1260 tattctgaaa taggcatgaa aggagagcgg agaaggggaa aagggcacga cggtttgtac 1320 cagggactca gcactgctac gaaggatact tatgacgctc tccacatgca agccctgcca 1380 cctagg 1386 <210> 110 <211> 462 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 110 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu 100 105 110 Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly 115 120 125 Gly Gly Gly Ser Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser 130 135 140 Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser 145 150 155 160 Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro 165 170 175 Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala 180 185 190 Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser 195 200 205 Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asp 210 215 220 Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys Arg 225 230 235 240 Ala Ala Ala Ile Glu Val Met Tyr Pro Pro Pro Tyr Leu Asp Asn Glu 245 250 255 Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro 260 265 270 Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val 275 280 285 Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe 290 295 300 Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp 305 310 315 320 Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr 325 330 335 Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val 340 345 350 Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn 355 360 365 Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val 370 375 380 Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg 385 390 395 400 Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys 405 410 415 Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg 420 425 430 Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys 435 440 445 Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 450 455 460 <210> 111 <211> 1533 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 111 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccgcaggtgc agttggttga atcaggaggg ggtgtggtgc aacccggtcg gtcactgcgc 120 ctcagttgtg ctgcttccgg gtttactttc agctcatatg ggatgcactg ggtacggcag 180 gctccaggta aaggcttgga atgggtggcg gtgatcagct atgacggctc tgacaaatat 240 tatgtggact ccgtgaaagg cagattcacc atcagtcgag acaactcaaa gaatagactc 300 tacttgcaga tgaatagcct ccgggccgaa gatactgcag tctattattg cgcccgggag 360 cgctacagtg gaagagacta ttgggggcaa ggaactcttg tcacagtctc atctggcggc 420 ggcggcagcg gtgggggcgg atctggcggg ggcggcagcg aaatcgttat gactcagagt 480 cctgccacac tgagcgttag ccctggtgag agagcaacac ttagctgcag agctagtcag 540 agtgtttcca gtcttttgac atggtaccaa cagaagcccg gtcaagctcc acgactgctc 600 atcttcggtg catccacccg cgcaaccggg atacccgccc ggttttccgg ttctggaagt 660 ggcacaggat tcacgctcac catttcttct ctgcagtctg aagactttgc cgtgtattac 720 tgccagcagt acgatacctg gccctttacc tttggcccag gtactaaagt ggattttaaa 780 cgagctgctg cactttccaa tagtattatg tacttttcac attttgtgcc cgtgttcctg 840 cctgcgaagc ctacgacaac cccagcccct aggccgccca caccggcccc aactattgcc 900 tcccagccat tgtctctgag acccgaagct tgcagacctg ctgctggagg cgccgttcac 960 acccgaggat tggatttcgc atgtgacatt tacatctggg cccctttggc cggaacctgc 1020 ggtgtgctgc tgctgtcact cgtgattaca ctttactgca accaccgaaa cagatccaaa 1080 agaagccgcc tgctccatag cgattacatg aatatgactc cacgccgccc tggccccaca 1140 aggaaacact accagcctta cgcaccacct agagatttcg ctgcctatcg gagcagggtg 1200 aagttttcca gatctgcaga tgcaccagcg tatcagcagg gccagaacca actgtataac 1260 gagctcaacc tgggacgcag ggaagagtat gacgttttgg acaagcgcag aggacgggac 1320 cctgagatgg gtggcaaacc aagacgaaaa aacccccagg agggtctcta taatgagctg 1380 cagaaggata agatggctga agcctattct gaaataggca tgaaaggaga gcggagaagg 1440 ggaaaagggc acgacggttt gtaccaggga ctcagcactg ctacgaagga tacttatgac 1500 gctctccaca tgcaagccct gccacctagg taa 1533 <210> 112 <211> 509 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 112 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val 20 25 30 Val Gln Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe 35 40 45 Thr Phe Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys 50 55 60 Gly Leu Glu Trp Val Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr 65 70 75 80 Tyr Val Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser 85 90 95 Lys Asn Arg Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 100 105 110 Ala Val Tyr Tyr Cys Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp 115 120 125 Gly Gly Thr Leu Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly Gly 130 135 140 Gly Gly Ser Gly Gly Gly Gly Ser Glu Ile Val Met Thr Gln Ser Pro 145 150 155 160 Ala Thr Leu Ser Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys Arg 165 170 175 Ala Ser Gln Ser Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys Pro 180 185 190 Gly Gln Ala Pro Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala Thr 195 200 205 Gly Ile Pro Ala Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe Thr 210 215 220 Leu Thr Ile Ser Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr Cys 225 230 235 240 Gln Gln Tyr Asp Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys Val 245 250 255 Asp Phe Lys Arg Ala Ala Ala Leu Ser Asn Ser Ile Met Tyr Phe Ser 260 265 270 His Phe Val Pro Val Phe Leu Pro Ala Lys Pro Thr Thr Thr Pro Ala 275 280 285 Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile Ala Ser Gln Pro Leu Ser 290 295 300 Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala Gly Gly Ala Val His Thr 305 310 315 320 Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr Ile Trp Ala Pro Leu Ala 325 330 335 Gly Thr Cys Gly Val Leu Leu Leu Ser Leu Val Ile Thr Leu Tyr Cys 340 345 350 Asn His Arg Asn Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr 355 360 365 Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln 370 375 380 Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys 385 390 395 400 Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln 405 410 415 Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu 420 425 430 Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg 435 440 445 Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met 450 455 460 Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly 465 470 475 480 Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp 485 490 495 Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 500 505 <210> 113 <211> 1467 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 113 caggtgcagt tggttgaatc aggagggggt gtggtgcaac ccggtcggtc actgcgcctc 60 agttgtgctg cttccgggtt tactttcagc tcatatggga tgcactgggt acggcaggct 120 ccaggtaaag gcttggaatg ggtggcggtg atcagctatg acggctctga caaatattat 180 gtggactccg tgaaaggcag attcaccatc agtcgagaca actcaaagaa tagactctac 240 ttgcagatga atagcctccg ggccgaagat actgcagtct attattgcgc ccgggagcgc 300 tacagtggaa gagactattg ggggcaagga actcttgtca cagtctcatc tggcggcggc 360 ggcagcggtg ggggcggatc tggcgggggc ggcagcgaaa tcgttatgac tcagagtcct 420 gccacactga gcgttagccc tggtgagaga gcaacactta gctgcagagc tagtcagagt 480 gtttccagtc ttttgacatg gtaccaacag aagcccggtc aagctccacg actgctcatc 540 ttcggtgcat ccacccgcgc aaccgggata cccgcccggt tttccggttc tggaagtggc 600 acaggattca cgctcaccat ttcttctctg cagtctgaag actttgccgt gtattactgc 660 cagcagtacg atacctggcc ctttaccttt ggcccaggta ctaaagtgga ttttaaacga 720 gctgctgcac tttccaatag tattatgtac ttttcacatt ttgtgcccgt gttcctgcct 780 gcgaagccta cgacaacccc agcccctagg ccgcccacac cggccccaac tattgcctcc 840 cagccattgt ctctgagacc cgaagcttgc agacctgctg ctggaggcgc cgttcacacc 900 cgaggattgg atttcgcatg tgacatttac atctgggccc ctttggccgg aacctgcggt 960 gtgctgctgc tgtcactcgt gattacactt tactgcaacc accgaaacag atccaaaaga 1020 agccgcctgc tccatagcga ttacatgaat atgactccac gccgccctgg ccccacaagg 1080 aaacactacc agccttacgc accacctaga gatttcgctg cctatcggag cagggtgaag 1140 ttttccagat ctgcagatgc accagcgtat cagcagggcc agaaccaact gtataacgag 1200 ctcaacctgg gacgcaggga agagtatgac gttttggaca agcgcagagg acgggaccct 1260 gagatgggtg gcaaaccaag acgaaaaaac ccccaggagg gtctctataa tgagctgcag 1320 aaggataaga tggctgaagc ctattctgaa ataggcatga aaggagagcg gagaagggga 1380 aaagggcacg acggtttgta ccagggactc agcactgcta cgaaggatac ttatgacgct 1440 ctccacatgc aagccctgcc acctagg 1467 <210> 114 <211> 489 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 114 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu 100 105 110 Val Thr Val Ser Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly 115 120 125 Gly Gly Gly Ser Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser 130 135 140 Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser 145 150 155 160 Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro 165 170 175 Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala 180 185 190 Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser 195 200 205 Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asp 210 215 220 Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys Arg 225 230 235 240 Ala Ala Ala Leu Ser Asn Ser Ile Met Tyr Phe Ser His Phe Val Pro 245 250 255 Val Phe Leu Pro Ala Lys Pro Thr Thr Thr Pro Ala Pro Arg Pro Pro 260 265 270 Thr Pro Ala Pro Thr Ile Ala Ser Gln Pro Leu Ser Leu Arg Pro Glu 275 280 285 Ala Cys Arg Pro Ala Ala Gly Gly Ala Val His Thr Arg Gly Leu Asp 290 295 300 Phe Ala Cys Asp Ile Tyr Ile Trp Ala Pro Leu Ala Gly Thr Cys Gly 305 310 315 320 Val Leu Leu Leu Ser Leu Val Ile Thr Leu Tyr Cys Asn His Arg Asn 325 330 335 Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr 340 345 350 Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro 355 360 365 Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser 370 375 380 Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu 385 390 395 400 Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg 405 410 415 Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln 420 425 430 Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr 435 440 445 Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp 450 455 460 Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala 465 470 475 480 Leu His Met Gln Ala Leu Pro Pro Arg 485 <210> 115 <211> 1425 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 115 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccggagattg tgatgaccca gtcccctgct accctgtccg tcagtccggg cgagagagcc 120 accttgtcat gccgggccag ccagtccgtc agcagtctcc tgacttggta tcagcaaaaa 180 ccagggcagg caccgcggct tttgattttt ggtgcaagca cacgcgccac tggcattcca 240 gctaggtttt ctggaagtgg atctgggaca ggcttcactc tgacaatcag tagcctgcag 300 agtgaggact ttgctgttta ctactgtcaa cagtacgaca cctggccatt cacattcggg 360 cccggcacca aggtcgactt caagaggggc ggtggaggtt caggtggtgg cgggtcaggc 420 ggcggtgggt ctcaggttca actggtggaa tcaggtggcg gcgttgtcca accggggcga 480 tcacttcgac tttcctgtgc tgcctcaggc tttacttttt catcctatgg gatgcactgg 540 gttcggcagg ctcccggaaa aggactcgag tgggttgcag tgatctctta cgatggctca 600 gacaagtatt atgtggactc agtcaagggg agattcacaa taagccgaga caactccaaa 660 aaccggcttt atctccagat gaacagcctt agagcggaag ataccgcggt atactactgt 720 gcccgcgaga ggtattccgg cagagactac tggggacagg gcacactggt caccgtgagt 780 tctgccgcag cgctcgataa cgaaaagagc aacggaacca ttatccacgt taagggcaag 840 cacctgtgcc ccagtcccct cttcccagga ccatctaaac ccttctgggt tctggtagta 900 gttggagggg tccttgcatg ttactccctt ttggtcaccg tcgccttcat tattttctgg 960 gtgagatcca aaagaagccg cctgctccat agcgattaca tgaatatgac tccacgccgc 1020 cctggcccca caaggaaaca ctaccagcct tacgcaccac ctagagattt cgctgcctat 1080 cggagcaggg tgaagttttc cagatctgca gatgcaccag cgtatcagca gggccagaac 1140 caactgtata acgagctcaa cctgggacgc agggaagagt atgacgtttt ggacaagcgc 1200 agaggacggg accctgagat gggtggcaaa ccaagacgaa aaaaccccca ggagggtctc 1260 tataatgagc tgcagaagga taagatggct gaagcctatt ctgaaatagg catgaaagga 1320 gagcggagaa ggggaaaagg gcacgacggt ttgtaccagg gactcagcac tgctacgaag 1380 gatacttatg acgctctcca catgcaagcc ctgccaccta ggtaa 1425 <210> 116 <211> 474 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 116 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu 20 25 30 Ser Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln 35 40 45 Ser Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala 50 55 60 Pro Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro 65 70 75 80 Ala Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile 85 90 95 Ser Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr 100 105 110 Asp Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys 115 120 125 Arg Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 130 135 140 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 145 150 155 160 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 165 170 175 Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 180 185 190 Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val 195 200 205 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr 210 215 220 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 225 230 235 240 Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu 245 250 255 Val Thr Val Ser Ser Ala Ala Ala Leu Asp Asn Glu Lys Ser Asn Gly 260 265 270 Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe 275 280 285 Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val 290 295 300 Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp 305 310 315 320 Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met 325 330 335 Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala 340 345 350 Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg 355 360 365 Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn 370 375 380 Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg 385 390 395 400 Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro 405 410 415 Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala 420 425 430 Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His 435 440 445 Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp 450 455 460 Ala Leu His Met Gln Ala Leu Pro Pro Arg 465 470 <210> 117 <211> 1359 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 117 gagattgtga tgacccagtc ccctgctacc ctgtccgtca gtccgggcga gagagccacc 60 ttgtcatgcc gggccagcca gtccgtcagc agtctcctga cttggtatca gcaaaaacca 120 gggcaggcac cgcggctttt gatttttggt gcaagcacac gcgccactgg cattccagct 180 aggttttctg gaagtggatc tgggacaggc ttcactctga caatcagtag cctgcagagt 240 gaggactttg ctgtttacta ctgtcaacag tacgacacct ggccattcac attcgggccc 300 ggcaccaagg tcgacttcaa gaggggcggt ggaggttcag gtggtggcgg gtcaggcggc 360 ggtgggtctc aggttcaact ggtggaatca ggtggcggcg ttgtccaacc ggggcgatca 420 cttcgacttt cctgtgctgc ctcaggcttt actttttcat cctatgggat gcactgggtt 480 cggcaggctc ccggaaaagg actcgagtgg gttgcagtga tctcttacga tggctcagac 540 aagtattatg tggactcagt caaggggaga ttcacaataa gccgagacaa ctccaaaaac 600 cggctttatc tccagatgaa cagccttaga gcggaagata ccgcggtata ctactgtgcc 660 cgcgagaggt attccggcag agactactgg ggacagggca cactggtcac cgtgagttct 720 gccgcagcgc tcgataacga aaagagcaac ggaaccatta tccacgttaa gggcaagcac 780 ctgtgcccca gtcccctctt cccaggacca tctaaaccct tctgggttct ggtagtagtt 840 ggaggggtcc ttgcatgtta ctcccttttg gtcaccgtcg ccttcattat tttctgggtg 900 agatccaaaa gaagccgcct gctccatagc gattacatga atatgactcc acgccgccct 960 ggccccacaa ggaaacacta ccagccttac gcaccaccta gagatttcgc tgcctatcgg 1020 agcagggtga agttttccag atctgcagat gcaccagcgt atcagcaggg ccagaaccaa 1080 ctgtataacg agctcaacct gggacgcagg gaagagtatg acgttttgga caagcgcaga 1140 ggacgggacc ctgagatggg tggcaaacca agacgaaaaa acccccagga gggtctctat 1200 aatgagctgc agaaggataa gatggctgaa gcctattctg aaataggcat gaaaggagag 1260 cggagaaggg gaaaagggca cgacggtttg taccagggac tcagcactgc tacgaaggat 1320 acttatgacg ctctccacat gcaagccctg ccacctagg 1359 <210> 118 <211> 453 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 118 Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Leu 20 25 30 Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asp Thr Trp Pro Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys Arg Gly Gly Gly Gly 100 105 110 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gln Val Gln Leu Val 115 120 125 Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg Ser Leu Arg Leu Ser 130 135 140 Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr Gly Met His Trp Val 145 150 155 160 Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val Ala Val Ile Ser Tyr 165 170 175 Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val Lys Gly Arg Phe Thr 180 185 190 Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr Leu Gln Met Asn Ser 195 200 205 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Arg Tyr 210 215 220 Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 225 230 235 240 Ala Ala Ala Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val 245 250 255 Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys 260 265 270 Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser 275 280 285 Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg 290 295 300 Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro 305 310 315 320 Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe 325 330 335 Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro 340 345 350 Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly 355 360 365 Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro 370 375 380 Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr 385 390 395 400 Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly 405 410 415 Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln 420 425 430 Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln 435 440 445 Ala Leu Pro Pro Arg 450 <210> 119 <211> 1452 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 119 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccggagatcg tcatgacaca gagtccagct accctgagcg tgtcccctgg agagagagcc 120 accctgtcct gtagggctag tcagagtgtg tccagcctcc tcacctggta tcaacagaag 180 cctggtcaag ctccccggct gcttatcttc ggggccagca cgcgagccac aggcatcccg 240 gccagattct ctggctctgg cagtggcacc gggttcactc tcacgatctc atccctgcag 300 tcagaggatt tcgctgtgta ttactgtcag cagtacgata catggccctt caccttcggc 360 ccgggcacaa aagtagattt caagcgcggc ggcgggggta gtgggggcgg gggatcagga 420 ggagggggct cccaagtaca gctggttgag agcggcggcg gggtggttca gcccgggcgc 480 agcctcaggc tgagttgcgc agcatcagga ttcacattca gttcttatgg aatgcattgg 540 gtcagacagg ctcccgggaa gggccttgaa tgggtggcag tcattagcta cgacggaagc 600 gataagtact atgtggactc agttaaaggg agatttacta tcagccgcga caattccaaa 660 aacagattgt atttgcagat gaactccctc agggcggagg acactgctgt atattactgc 720 gcacgagaga gatactccgg ccgagactat tggggccaag gaacattggt aactgtgagc 780 tccgccgcag ctattgaggt catgtacccc ccaccttatc tcgataatga gaagagtaat 840 gggactataa ttcacgtaaa gggcaaacac ctgtgccctt ccccgctgtt tccaggtcca 900 agtaagccgt tctgggtcct ggttgtggtg ggaggggtgc tggcctgcta ttctctgttg 960 gttaccgtgg cctttatcat tttctgggtg agatccaaaa gaagccgcct gctccatagc 1020 gattacatga atatgactcc acgccgccct ggccccacaa ggaaacacta ccagccttac 1080 gcaccaccta gagatttcgc tgcctatcgg agcagggtga agttttccag atctgcagat 1140 gcaccagcgt atcagcaggg ccagaaccaa ctgtataacg agctcaacct gggacgcagg 1200 gaagagtatg acgttttgga caagcgcaga ggacgggacc ctgagatggg tggcaaacca 1260 agacgaaaaa acccccagga gggtctctat aatgagctgc agaaggataa gatggctgaa 1320 gcctattctg aaataggcat gaaaggagag cggagaaggg gaaaagggca cgacggtttg 1380 taccagggac tcagcactgc tacgaaggat acttatgacg ctctccacat gcaagccctg 1440 ccacctaggt aa 1452 <210> 120 <211> 483 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 120 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu 20 25 30 Ser Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln 35 40 45 Ser Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala 50 55 60 Pro Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro 65 70 75 80 Ala Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile 85 90 95 Ser Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr 100 105 110 Asp Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys 115 120 125 Arg Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 130 135 140 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 145 150 155 160 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 165 170 175 Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 180 185 190 Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val 195 200 205 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr 210 215 220 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 225 230 235 240 Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu 245 250 255 Val Thr Val Ser Ser Ala Ala Ala Ile Glu Val Met Tyr Pro Pro Pro 260 265 270 Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly 275 280 285 Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe 290 295 300 Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu 305 310 315 320 Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg 325 330 335 Leu Leu His Ser Asp Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro 340 345 350 Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala 355 360 365 Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr 370 375 380 Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg 385 390 395 400 Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met 405 410 415 Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu 420 425 430 Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys 435 440 445 Gly Glu Arg Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu 450 455 460 Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu 465 470 475 480 Pro Pro Arg <210> 121 <211> 1386 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 121 gagatcgtca tgacacagag tccagctacc ctgagcgtgt cccctggaga gagagccacc 60 ctgtcctgta gggctagtca gagtgtgtcc agcctcctca cctggtatca acagaagcct 120 ggtcaagctc cccggctgct tatcttcggg gccagcacgc gagccacagg catcccggcc 180 agattctctg gctctggcag tggcaccggg ttcactctca cgatctcatc cctgcagtca 240 gaggatttcg ctgtgtatta ctgtcagcag tacgatacat ggcccttcac cttcggcccg 300 ggcacaaaag tagatttcaa gcgcggcggc gggggtagtg ggggcggggg atcaggagga 360 gggggctccc aagtacagct ggttgagagc ggcggcgggg tggttcagcc cgggcgcagc 420 ctcaggctga gttgcgcagc atcaggattc acattcagtt cttatggaat gcattgggtc 480 agacaggctc ccgggaaggg ccttgaatgg gtggcagtca ttagctacga cggaagcgat 540 aagtactatg tggactcagt taaagggaga tttactatca gccgcgacaa ttccaaaaac 600 agattgtatt tgcagatgaa ctccctcagg gcggaggaca ctgctgtata ttactgcgca 660 cgagagagat actccggccg agactattgg ggccaaggaa cattggtaac tgtgagctcc 720 gccgcagcta ttgaggtcat gtacccccca ccttatctcg ataatgagaa gagtaatggg 780 actataattc acgtaaaggg caaacacctg tgcccttccc cgctgtttcc aggtccaagt 840 aagccgttct gggtcctggt tgtggtggga ggggtgctgg cctgctattc tctgttggtt 900 accgtggcct ttatcatttt ctgggtgaga tccaaaagaa gccgcctgct ccatagcgat 960 tacatgaata tgactccacg ccgccctggc cccacaagga aacactacca gccttacgca 1020 ccacctagag atttcgctgc ctatcggagc agggtgaagt tttccagatc tgcagatgca 1080 ccagcgtatc agcagggcca gaaccaactg tataacgagc tcaacctggg acgcagggaa 1140 gagtatgacg ttttggacaa gcgcagagga cgggaccctg agatgggtgg caaaccaaga 1200 cgaaaaaacc cccaggaggg tctctataat gagctgcaga aggataagat ggctgaagcc 1260 tattctgaaa taggcatgaa aggagagcgg agaaggggaa aagggcacga cggtttgtac 1320 cagggactca gcactgctac gaaggatact tatgacgctc tccacatgca agccctgcca 1380 cctagg 1386 <210> 122 <211> 462 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 122 Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Leu 20 25 30 Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asp Thr Trp Pro Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys Arg Gly Gly Gly Gly 100 105 110 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gln Val Gln Leu Val 115 120 125 Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg Ser Leu Arg Leu Ser 130 135 140 Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr Gly Met His Trp Val 145 150 155 160 Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val Ala Val Ile Ser Tyr 165 170 175 Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val Lys Gly Arg Phe Thr 180 185 190 Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr Leu Gln Met Asn Ser 195 200 205 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Arg Tyr 210 215 220 Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 225 230 235 240 Ala Ala Ala Ile Glu Val Met Tyr Pro Pro Pro Tyr Leu Asp Asn Glu 245 250 255 Lys Ser Asn Gly Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro 260 265 270 Ser Pro Leu Phe Pro Gly Pro Ser Lys Pro Phe Trp Val Leu Val Val 275 280 285 Val Gly Gly Val Leu Ala Cys Tyr Ser Leu Leu Val Thr Val Ala Phe 290 295 300 Ile Ile Phe Trp Val Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp 305 310 315 320 Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr 325 330 335 Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val 340 345 350 Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn 355 360 365 Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val 370 375 380 Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg 385 390 395 400 Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys 405 410 415 Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg 420 425 430 Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys 435 440 445 Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 450 455 460 <210> 123 <211> 1533 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 123 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccggaaatag tgatgactca gtccccggcc accctcagcg tgtcccccgg ggagcgagcg 120 accctgtcat gcagggcttc ccagagtgtc agctccctgc tcacttggta tcagcaaaag 180 ccggggcagg ctccccgcct cctcatcttc ggggcatcaa ctagggccac cggcattcct 240 gcaagatttt ccgggtctgg cagcggcacc ggcttcaccc ttaccattag ctctctgcag 300 tctgaggact tcgccgttta ctattgtcag cagtatgata cttggccctt taccttcggt 360 cccggaacta aggtggactt caagcgcggg gggggtggat ctggaggtgg tggctccggg 420 ggcggtggaa gccaggtcca gttggttgag agcggcggcg gagtggtgca gcccgggagg 480 tccttgcggc tgagctgtgc agcctccggt tttacttttt ctagctatgg aatgcattgg 540 gtaagacagg ctcccggaaa aggcctcgag tgggtggcgg tcattagcta tgatggatct 600 gataaatact atgtggactc agttaagggg cgcttcacaa tctcaagaga caatagcaaa 660 aatagactgt acctgcagat gaatagtctg cgcgccgagg acactgccgt gtactactgc 720 gcccgcgaga gatacagcgg acgggattac tggggccagg gtaccctcgt aacggtgtcc 780 tccgctgccg cccttagcaa cagcattatg tacttttctc atttcgtgcc agtctttctc 840 ccagcaaagc ccaccactac cccggccccc aggccgccta ctcctgcccc cactatcgcg 900 tctcagcctc tctccttgcg gcccgaggcc tgccggccag ccgcaggggg cgccgtacat 960 actcggggtt tggatttcgc ttgcgacata tatatttggg cccccctcgc cggcacatgt 1020 ggagtgctgc tcctgagtct cgttataacc ctctattgca accatagaaa cagatccaaa 1080 agaagccgcc tgctccatag cgattacatg aatatgactc cacgccgccc tggccccaca 1140 aggaaacact accagcctta cgcaccacct agagatttcg ctgcctatcg gagcagggtg 1200 aagttttcca gatctgcaga tgcaccagcg tatcagcagg gccagaacca actgtataac 1260 gagctcaacc tgggacgcag ggaagagtat gacgttttgg acaagcgcag aggacgggac 1320 cctgagatgg gtggcaaacc aagacgaaaa aacccccagg agggtctcta taatgagctg 1380 cagaaggata agatggctga agcctattct gaaataggca tgaaaggaga gcggagaagg 1440 ggaaaagggc acgacggttt gtaccaggga ctcagcactg ctacgaagga tacttatgac 1500 gctctccaca tgcaagccct gccacctagg taa 1533 <210> 124 <211> 510 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 124 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu 20 25 30 Ser Val Ser Pro Gly Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln 35 40 45 Ser Val Ser Ser Leu Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala 50 55 60 Pro Arg Leu Leu Ile Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro 65 70 75 80 Ala Arg Phe Ser Gly Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile 85 90 95 Ser Ser Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr 100 105 110 Asp Thr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys 115 120 125 Arg Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 130 135 140 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 145 150 155 160 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 165 170 175 Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 180 185 190 Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val 195 200 205 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr 210 215 220 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 225 230 235 240 Ala Arg Glu Arg Tyr Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu 245 250 255 Val Thr Val Ser Ser Ala Ala Ala Leu Ser Asn Ser Ile Met Tyr Phe 260 265 270 Ser His Phe Val Pro Val Phe Leu Pro Ala Lys Pro Thr Thr Thr Pro 275 280 285 Ala Pro Arg Pro Pro Thr Pro Ala Pro Thr Ile Ala Ser Gln Pro Leu 290 295 300 Ser Leu Arg Pro Glu Ala Cys Arg Pro Ala Ala Gly Gly Ala Val His 305 310 315 320 Thr Arg Gly Leu Asp Phe Ala Cys Asp Ile Tyr Ile Trp Ala Pro Leu 325 330 335 Ala Gly Thr Cys Gly Val Leu Leu Leu Ser Leu Val Ile Thr Leu Tyr 340 345 350 Cys Asn His Arg Asn Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp 355 360 365 Tyr Met Asn Met Thr Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr 370 375 380 Gln Pro Tyr Ala Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val 385 390 395 400 Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn 405 410 415 Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val 420 425 430 Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg 435 440 445 Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys 450 455 460 Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg 465 470 475 480 Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys 485 490 495 Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 500 505 510 <210> 125 <211> 1467 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polinucleótido sintético <400> 125 gaaatagtga tgactcagtc cccggccacc ctcagcgtgt cccccgggga gcgagcgacc 60 ctgtcatgca gggcttccca gagtgtcagc tccctgctca cttggtatca gcaaaagccg 120 gggcaggctc cccgcctcct catcttcggg gcatcaacta gggccaccgg cattcctgca 180 agattttccg ggtctggcag cggcaccggc ttcaccctta ccattagctc tctgcagtct 240 gaggacttcg ccgtttacta ttgtcagcag tatgatactt ggccctttac cttcggtccc 300 ggaactaagg tggacttcaa gcgcgggggg ggtggatctg gaggtggtgg ctccgggggc 360 ggtggaagcc aggtccagtt ggttgagagc ggcggcggag tggtgcagcc cgggaggtcc 420 ttgcggctga gctgtgcagc ctccggtttt actttttcta gctatggaat gcattgggta 480 agacaggctc ccggaaaagg cctcgagtgg gtggcggtca ttagctatga tggatctgat 540 aaatactatg tggactcagt taaggggcgc ttcacaatct caagagacaa tagcaaaaat 600 agactgtacc tgcagatgaa tagtctgcgc gccgaggaca ctgccgtgta ctactgcgcc 660 cgcgagagat acagcggacg ggattactgg ggccagggta ccctcgtaac ggtgtcctcc 720 gctgccgccc ttagcaacag cattatgtac ttttctcatt tcgtgccagt ctttctccca 780 gcaaagccca ccactacccc ggcccccagg ccgcctactc ctgcccccac tatcgcgtct 840 cagcctctct ccttgcggcc cgaggcctgc cggccagccg cagggggcgc cgtacatact 900 cggggtttgg atttcgcttg cgacatatat atttgggccc ccctcgccgg cacatgtgga 960 gtgctgctcc tgagtctcgt tataaccctc tattgcaacc atagaaacag atccaaaaga 1020 agccgcctgc tccatagcga ttacatgaat atgactccac gccgccctgg ccccacaagg 1080 aaacactacc agccttacgc accacctaga gatttcgctg cctatcggag cagggtgaag 1140 ttttccagat ctgcagatgc accagcgtat cagcagggcc agaaccaact gtataacgag 1200 ctcaacctgg gacgcaggga agagtatgac gttttggaca agcgcagagg acgggaccct 1260 gagatgggtg gcaaaccaag acgaaaaaac ccccaggagg gtctctataa tgagctgcag 1320 aaggataaga tggctgaagc ctattctgaa ataggcatga aaggagagcg gagaagggga 1380 aaagggcacg acggtttgta ccagggactc agcactgcta cgaaggatac ttatgacgct 1440 ctccacatgc aagccctgcc acctagg 1467 <210> 126 <211> 489 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Polipéptido sintético <400> 126 Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Leu 20 25 30 Leu Thr Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asp Thr Trp Pro Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Phe Lys Arg Gly Gly Gly Gly 100 105 110 Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gln Val Gln Leu Val 115 120 125 Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg Ser Leu Arg Leu Ser 130 135 140 Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr Gly Met His Trp Val 145 150 155 160 Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val Ala Val Ile Ser Tyr 165 170 175 Asp Gly Ser Asp Lys Tyr Tyr Val Asp Ser Val Lys Gly Arg Phe Thr 180 185 190 Ile Ser Arg Asp Asn Ser Lys Asn Arg Leu Tyr Leu Gln Met Asn Ser 195 200 205 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Arg Tyr 210 215 220 Ser Gly Arg Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 225 230 235 240 Ala Ala Ala Leu Ser Asn Ser Ile Met Tyr Phe Ser His Phe Val Pro 245 250 255 Val Phe Leu Pro Ala Lys Pro Thr Thr Thr Pro Ala Pro Arg Pro Pro 260 265 270 Thr Pro Ala Pro Thr Ile Ala Ser Gln Pro Leu Ser Leu Arg Pro Glu 275 280 285 Ala Cys Arg Pro Ala Ala Gly Gly Ala Val His Thr Arg Gly Leu Asp 290 295 300 Phe Ala Cys Asp Ile Tyr Ile Trp Ala Pro Leu Ala Gly Thr Cys Gly 305 310 315 320 Val Leu Leu Leu Ser Leu Val Ile Thr Leu Tyr Cys Asn His Arg Asn 325 330 335 Arg Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr 340 345 350 Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala Pro 355 360 365 Pro Arg Asp Phe Ala Ala Tyr Arg Ser Arg Val Lys Phe Ser Arg Ser 370 375 380 Ala Asp Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu 385 390 395 400 Leu Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg 405 410 415 Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro Gln 420 425 430 Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu Ala Tyr 435 440 445 Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys Gly His Asp 450 455 460 Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp Thr Tyr Asp Ala 465 470 475 480 Leu His Met Gln Ala Leu Pro Pro Arg 485 <210> 127 <211> 63 <212> ADN <213> Homo sapiens <400> 127 atggcactcc ccgtaactgc tctgctgctg ccgttggcat tgctcctgca cgccgcacgc 60 ccg 63 <210> 128 <211> 21 <212> PRT <213> Homo sapiens <400> 128 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro 20 <210> 129 <211> 45 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Oligonucleótido sintético <400> 129 ggcggtggag gctccggagg ggggggctct ggcggagggg gctcc 45 <210> 130 <211> 15 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 130 Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser 1 5 10 15 <210> 131 <211> 54 <212> ADN <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Oligonucleótido sintético <400> 131 gggtctacat ccggctccgg gaagcccgga agtggcgaag gtagtacaaa gggg 54 <210> 132 <211> 18 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 132 Gly Ser Thr Ser Gly Ser Gly Lys Pro Gly Ser Gly Glu Gly Ser Thr 1 5 10 15 Lys Gly <210> 133 <211> 152 <212> PRT <213> Homo sapiens <400> 133 Met Leu Arg Leu Leu Leu Ala Leu Asn Leu Phe Pro Ser Ile Gln Val 1 5 10 15 Thr Gly Asn Lys Ile Leu Val Lys Gln Ser Pro Met Leu Val Ala Tyr 20 25 30 Asp Asn Ala Val Asn Leu Ser Cys Lys Tyr Ser Tyr Asn Leu Phe Ser 35 40 45 Arg Glu Phe Arg Ala Ser Leu His Lys Gly Leu Asp Ser Ala Val Glu 50 55 60 Val Cys Val Val Tyr Gly Asn Tyr Ser Gln Gln Leu Gln Val Tyr Ser 65 70 75 80 Lys Thr Gly Phe Asn Cys Asp Gly Lys Leu Gly Asn Glu Ser Val Thr 85 90 95 Phe Tyr Leu Gln Asn Leu Tyr Val Asn Gln Thr Asp Ile Tyr Phe Cys 100 105 110 Lys Ile Glu Val Met Tyr Pro Pro Pro Tyr Leu Asp Asn Glu Lys Ser 115 120 125 Asn Gly Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro 130 135 140 Leu Phe Pro Gly Pro Ser Lys Pro 145 150 <210> 134 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <220> <221> MOD_RES <222> (2)..(2) <223> Gly, Phe o Tyr <220> <221> MOD_RES <222> (3)..(3) <223> Ser o Thr <220> <221> MOD_RES <222> (4)..(4) <223> Ile, Phe o Leu <220> <221> MOD_RES <222> (5)..(5) <223> Ser o Thr <220> <221> MOD_RES <222> (6)..(7) <223> Pueden o no estar presentes <220> <221> MOD_RES <222> (8)..(8) <223> Glu, Gly o ausente <220> <221> MOD_RES <222> (9)..(9) <223> Phe, Leu o Tyr <400> 134 Gly Xaa Xaa Xaa Xaa Ser Gly Xaa Xaa 1 5 <210> 135 <211> 6 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <220> <221> MOD_RES <222> (1)..(1) <223> Asp, His, Ser o Tyr <220> <221> MOD_RES <222> (2)..(2) <223> His, Pro o Tyr <220> <221> MOD_RES <222> (3)..(3) <223> Asp, Glu o Ser <220> <221> MOD_RES <222> (4)..(4) <223> Asp o Gly <220> <221> MOD_RES <222> (5)..(5) <223> Gly o Ser <220> <221> MOD_RES <222> (6)..(6) <223> Asp, Glu o ausente <400> 135 Xaa Xaa Xaa Xaa Xaa Xaa 1 5 <210> 136 <211> 14 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <220> <221> MOD_RES <222> (1)..(1) <223> Glu o Leu <220> <221> MOD_RES <222> (2)..(2) <223> Arg, Ser o Val <220> <221> MOD_RES <222> (3)..(3) <223> Arg o Tyr <220> <221> MOD_RES <222> (4)..(4) <223> Cys, Gly o Ser <220> <221> MOD_RES <222> (5)..(5) <223> Gly, Ile o ausente <220> <221> MOD_RES <222> (6)..(8) <223> Pueden o no estar presentes <220> <221> MOD_RES <222> (9)..(9) <223> Trp, Tyr o ausente <220> <221> MOD_RES <222> (10)..(10) <223> Pro, Ser o ausente <220> <221> MOD_RES <222> (11)..(11) <223> Gly, Tyr o ausente <220> <221> MOD_RES <222> (12)..(12) <223> Phe o Arg <400> 136 Xaa Xaa Xaa Xaa Xaa Gly Asp Cys Xaa Xaa Xaa Xaa Asp Tyr 1 5 10 <210> 137 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <220> <221> MOD_RES <222> (1)..(1) <223> Gln o Arg <220> <221> MOD_RES <222> (5)..(5) <223> Asp o Ser <220> <221> MOD_RES <222> (6)..(6) <223> Ile o Val <220> <221> MOD_RES <222> (7)..(8) <223> Asn o Ser <220> <221> MOD_RES <222> (9)..(9) <223> Phe, Leu o Tyr <220> <221> MOD_RES <222> (11)..(11) <223> Asn o Thr <400> 137 Xaa Ala Ser Gln Xaa Xaa Xaa Xaa Xaa Leu Xaa 1 5 10 <210> 138 <211> 7 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <220> <221> MOD_RES <222> (1)..(1) <223> Asp o Gly <220> <221> MOD_RES <222> (4)..(4) <223> Asn, Ser o Thr <220> <221> MOD_RES <222> (5)..(5) <223> Leu o Arg <220> <221> MOD_RES <222> (6)..(6) <223> Ala, Glu o Lys <220> <221> MOD_RES <222> (7)..(7) <223> Ser o Thr <400> 138 Xaa Ala Ser Xaa Xaa Xaa Xaa 1 5 <210> 139 <211> 9 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <220> <221> MOD_RES <222> (3)..(3) <223> Ser o Tyr <220> <221> MOD_RES <222> (4)..(4) <223> Asp, Gly o Tyr <220> <221> MOD_RES <222> (5)..(5) <223> Asn, Ser o Thr <220> <221> MOD_RES <222> (6)..(6) <223> Leu, Thr o Tyr <220> <221> MOD_RES <222> (8)..(8) <223> Phe o Ile <400> 139 Gln Gln Xaa Xaa Xaa Xaa Pro Xaa Thr 1 5 <210> 140 <211> 265 <212> PRT <213> Homo sapiens <400> 140 Met Ser Glu Glu Val Thr Tyr Ala Asp Leu Gln Phe Gln Asn Ser Ser 1 5 10 15 Glu Met Glu Lys Ile Pro Glu Ile Gly Lys Phe Gly Glu Lys Ala Pro 20 25 30 Pro Ala Pro Ser His Val Trp Arg Pro Ala Ala Leu Phe Leu Thr Leu 35 40 45 Leu Cys Leu Leu Leu Leu Ile Gly Leu Gly Val Leu Ala Ser Met Phe 50 55 60 His Val Thr Leu Lys Ile Glu Met Lys Lys Met Asn Lys Leu Gln Asn 65 70 75 80 Ile Ser Glu Glu Leu Gln Arg Asn Ile Ser Leu Gln Leu Met Ser Asn 85 90 95 Met Asn Ile Ser Asn Lys Ile Arg Asn Leu Ser Thr Thr Leu Gln Thr 100 105 110 Ile Ala Thr Lys Leu Cys Arg Glu Leu Tyr Ser Lys Glu Gln Glu His 115 120 125 Lys Cys Lys Pro Cys Pro Arg Arg Trp Ile Trp His Lys Asp Ser Cys 130 135 140 Tyr Phe Leu Ser Asp Asp Val Gln Thr Trp Gln Glu Ser Lys Met Ala 145 150 155 160 Cys Ala Ala Gln Asn Ala Ser Leu Leu Lys Ile Asn Asn Lys Asn Ala 165 170 175 Leu Glu Phe Ile Lys Ser Gln Ser Arg Ser Tyr Asp Tyr Trp Leu Gly 180 185 190 Leu Ser Pro Glu Glu Asp Ser Thr Arg Gly Met Arg Val Asp Asn Ile 195 200 205 Ile Asn Ser Ser Ala Trp Val Ile Arg Asn Ala Pro Asp Leu Asn Asn 210 215 220 Met Tyr Cys Gly Tyr Ile Asn Arg Leu Tyr Val Gln Tyr Tyr His Cys 225 230 235 240 Thr Tyr Lys Lys Arg Met Ile Cys Glu Lys Met Ala Asn Pro Val Gln 245 250 255 Leu Gly Ser Thr Tyr Phe Arg Glu Ala 260 265 <210> 141 <211> 126 <212> ADN <213> Homo sapiens <400> 141 aagcgcggca ggaagaagct cctctacatt tttaagcagc cttttatgag gcccgtacag 60 acaacacagg aggaagatgg ctgtagctgc agatttcccg aggaggagga aggtgggtgc 120 gagctg 126 <210> 142 <211> 42 <212> PRT <213> Homo sapiens <400> 142 Lys Arg Gly Arg Lys Lys Leu Leu Tyr Ile Phe Lys Gln Pro Phe Met 1 5 10 15 Arg Pro Val Gln Thr Thr Gln Glu Glu Asp Gly Cys Ser Cys Arg Phe 20 25 30 Pro Glu Glu Glu Glu Gly Gly Cys Glu Leu 35 40 <210> 143 <211> 37 <212> PRT <213> Homo sapiens <400> 143 Arg Arg Asp Gln Arg Leu Pro Pro Asp Ala His Lys Pro Pro Gly Gly 1 5 10 15 Gly Ser Phe Arg Thr Pro Ile Gln Glu Glu Gln Ala Asp Ala His Ser 20 25 30 Thr Leu Ala Lys Ile 35 <210> 144 <211> 21 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 144 Met Ala Leu Pro Val Thr Ala Leu Leu Leu Pro Leu Ala Leu Leu Leu 1 5 10 15 His Ala Ala Arg Pro 20 <210> 145 <211> 20 <212> PRT <213> Secuencia Artificial <220> <223> Descripción de la Secuencia Artificial: Péptido sintético <400> 145 Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Ser Gly 1 5 10 15 Gly Gly Gly Ser 20 <210> 146 <211> 112 <212> PRT <213> Homo sapiens <400> 146 Arg Val Lys Phe Ser Arg Ser Ala Asp Ala Pro Ala Tyr Lys Gln Gly 1 5 10 15 Gln Asn Gln Leu Tyr Asn Glu Leu Asn Leu Gly Arg Arg Glu Glu Tyr 20 25 30 Asp Val Leu Asp Lys Arg Arg Gly Arg Asp Pro Glu Met Gly Gly Lys 35 40 45 Pro Arg Arg Lys Asn Pro Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys 50 55 60 Asp Lys Met Ala Glu Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg 65 70 75 80 Arg Arg Gly Lys Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala 85 90 95 Thr Lys Asp Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg 100 105 110 <210> 147 <211> 6762 <212> ADN <213> Lentivirus <400> 147 ctgacgcgcc ctgtagcggc gcattaagcg cggcgggtgt ggtggttacg cgcagcgtga 60 ccgctacact tgccagcgcc ctagcgcccg ctcctttcgc tttcttccct tcctttctcg 120 ccacgttcgc cggctttccc cgtcaagctc taaatcgggg gctcccttta gggttccgat 180 ttagtgcttt acggcacctc gaccccaaaa aacttgatta gggtgatggt tcacgtagtg 240 ggccatcgcc ctgatagacg gtttttcgcc ctttgacgtt ggagtccacg ttctttaata 300 gtggactctt gttccaaact ggaacaacac tcaaccctat ctcggtctat tcttttgatt 360 tataagggat tttgccgatt tcggcctatt ggttaaaaaa tgagctgatt taacaaaaat 420 ttaacgcgaa ttttaacaaa atattaacgc ttacaatttg ccattcgcca ttcaggctgc 480 gcaactgttg ggaagggcga tcggtgcggg cctcttcgct attacgccag ctggcgaaag 540 ggggatgtgc tgcaaggcga ttaagttggg taacgccagg gttttcccag tcacgacgtt 600 gtaaaacgac ggccagtgaa ttgtaatacg actcactata gggcgacccg gggatggcgc 660 gccagtaatc aattacgggg tcattagttc atagcccata tatggagttc cgcgttacat 720 aacttacggt aaatggcccg cctggctgac cgcccaacga cccccgccca ttgacgtcaa 780 taatgacgta tgttcccata gtaacgccaa tagggacttt ccattgacgt caatgggtgg 840 agtatttacg gtaaactgcc cacttggcag tacatcaagt gtatcatatg ccaagtacgc 900 cccctattga cgtcaatgac ggtaaatggc ccgcctggca ttatgcccag tacatgacct 960 tatgggactt tcctacttgg cagtacatct acgtattagt catcgctatt accatgctga 1020 tgcggttttg gcagtacatc aatgggcgtg gatagcggtt tgactcacgg ggatttccaa 1080 gtctccaccc cattgacgtc aatgggagtt tgttttggca ccaaaatcaa cgggactttc 1140 caaaatgtcg taacaactcc gccccattga cgcaaatggg cggtaggcgt gtacggtggg 1200 aggtctatat aagcagagct ggtttagtga accggggtct ctctggttag accagatctg 1260 agcctgggag ctctctggct aactagggaa cccactgctt aagcctcaat aaagcttgcc 1320 ttgagtgctt caagtagtgt gtgcccgtct gttgtgtgac tctggtaact agagatccct 1380 cagacccttt tagtcagtgt ggaaaatctc tagcagtggc gcccgaacag ggacttgaaa 1440 gcgaaaggga aaccagagga gctctctcga cgcaggactc ggcttgctga agcgcgcacg 1500 gcaagaggcg aggggcggcg actggtgagt acgccaaaaa ttttgactag cggaggctag 1560 aaggagagag atgggtgcga gagcgtcagt attaagcggg ggagaattag atcgcgatgg 1620 gaaaaaattc ggttaaggcc agggggaaag aaaaaatata aattaaaaca tatagtatgg 1680 gcaagcaggg agctagaacg attcgcagtt aatcctggcc tgttagaaac atcagaaggc 1740 tgtagacaaa tactgggaca gctacaacca tcccttcaga caggatcaga agaacttaga 1800 tcattatata atacagtagc aaccctctat tgtgtgcatc aaaggataga gataaaagac 1860 accaaggaag ctttagacaa gatagaggaa gagcaaaaca aaagtaagac caccgcacag 1920 caagccgccg ctgatcttca gacctggagg aggagatatg agggacaatt ggagaagtga 1980 attatataaa tataaagtag taaaaattga accattagga gtagcaccca ccaaggcaaa 2040 gagaagagtg gtgcagagag aaaaaagagc agtgggaata ggagctttgt tccttgggtt 2100 cttgggagca gcaggaagca ctatgggcgc agcgtcaatg acgctgacgg tacaggccag 2160 acaattattg tctggtatag tgcagcagca gaacaatttg ctgagggcta ttgaggcgca 2220 acagcatctg ttgcaactca cagtctgggg catcaagcag ctccaggcaa gaatcctggc 2280 tgtggaaaga tacctaaagg atcaacagct cctggggatt tggggttgct ctggaaaact 2340 catttgcacc actgctgtgc cttggaatgc tagttggagt aataaatctc tggaacagat 2400 ttggaatcac acgacctgga tggagtggga cagagaaatt aacaattaca caagcttaat 2460 acactcctta attgaagaat cgcaaaacca gcaagaaaag aatgaacaag aattattgga 2520 attagataaa tgggcaagtt tgtggaattg gtttaacata acaaattggc tgtggtatat 2580 aaaattattc ataatgatag taggaggctt ggtaggttta agaatagttt ttgctgtact 2640 ttctatagtg aatagagtta ggcagggata ttcaccatta tcgtttcaga cccacctccc 2700 aaccccgagg ggacccgaca ggcccgaagg aatagaagaa gaaggtggag agagagacag 2760 agacagatcc attcgattag tgaacggatc tcgacggtat cggttaactt ttaaaagaaa 2820 aggggggatt ggggggtaca gtgcagggga aagaatagta gacataatag caacagacat 2880 acaaactaaa gaattacaaa aacaaattac aaaattcaaa attttatcgc gatcgcggaa 2940 tgaaagaccc cacctgtagg tttggcaagc tagcttaagt aacgccattt tgcaaggcat 3000 ggaaaataca taactgagaa tagagaagtt cagatcaagg ttaggaacag agagacagca 3060 gaatatgggc caaacaggat atctgtggta agcagttcct gccccggctc agggccaaga 3120 acagatggtc cccagatgcg gtcccgccct cagcagtttc tagagaacca tcagatgttt 3180 ccagggtgcc ccaaggacct gaaaatgacc ctgtgcctta tttgaactaa ccaatcagtt 3240 cgcttctcgc ttctgttcgc gcgcttctgc tccccgagct caataaaaga gcccacaacc 3300 cctcactcgg cgcgccagtc cttcgaagta gatctttgtc gatcctacca tccactcgac 3360 acacccgcca gcggccgctg ccaagcttcc gagctctcga attaattcac ggtacccacc 3420 atggcctagg gagactagtc gaatcgatat caacctctgg attacaaaat ttgtgaaaga 3480 ttgactggta ttcttaacta tgttgctcct tttacgctat gtggatacgc tgctttaatg 3540 cctttgtatc atgctattgc ttcccgtatg gctttcattt tctcctcctt gtataaatcc 3600 tggttgctgt ctctttatga ggagttgtgg cccgttgtca ggcaacgtgg cgtggtgtgc 3660 actgtgtttg ctgacgcaac ccccactggt tggggcattg ccaccacctg tcagctcctt 3720 tccgggactt tcgctttccc cctccctatt gccacggcgg aactcatcgc cgcctgcctt 3780 gcccgctgct ggacaggggc tcggctgttg ggcactgaca attccgtggt gttgtcgggg 3840 aagctgacgt ccttttcatg gctgctcgcc tgtgttgcca cctggattct gcgcgggacg 3900 tccttctgct acgtcccttc ggccctcaat ccagcggacc ttccttcccg cggcctgctg 3960 ccggctctgc ggcctcttcc gcgtcttcgc cttcgccctc agacgagtcg gatctccctt 4020 tgggccgcct ccccgcctgg ttaattaaag tacctttaag accaatgact tacaaggcag 4080 ctgtagatct tagccacttt ttaaaagaaa aggggggact ggaagggcga attcactccc 4140 aacgaagaca agatctgctt tttgcttgta ctgggtctct ctggttagac cagatctgag 4200 cctgggagct ctctggctaa ctagggaacc cactgcttaa gcctcaataa agcttgcctt 4260 gagtgcttca agtagtgtgt gcccgtctgt tgtgtgactc tggtaactag agatccctca 4320 gaccctttta gtcagtgtgg aaaatctcta gcaggcatgc cagacatgat aagatacatt 4380 gatgagtttg gacaaaccac aactagaatg cagtgaaaaa aatgctttat ttgtgaaatt 4440 tgtgatgcta ttgctttatt tgtaaccatt ataagctgca ataaacaagt taacaacaac 4500 aattgcattc attttatgtt tcaggttcag ggggaggtgt gggaggtttt ttggcgcgcc 4560 atcgtcgagg ttccctttag tgagggttaa ttgcgagctt ggcgtaatca tggtcatagc 4620 tgtttcctgt gtgaaattgt tatccgctca caattccaca caacatacga gccggaagca 4680 taaagtgtaa agcctggggt gcctaatgag tgagctaact cacattaatt gcgttgcgct 4740 cactgcccgc tttccagtcg ggaaacctgt cgtgccagct gcattaatga atcggccaac 4800 gcgcggggag aggcggtttg cgtattgggc gctcttccgc ttcctcgctc actgactcgc 4860 tgcgctcggt cgttcggctg cggcgagcgg tatcagctca ctcaaaggcg gtaatacggt 4920 tatccacaga atcaggggat aacgcaggaa agaacatgtg agcaaaaggc cagcaaaagg 4980 ccaggaaccg taaaaaggcc gcgttgctgg cgtttttcca taggctccgc ccccctgacg 5040 agcatcacaa aaatcgacgc tcaagtcaga ggtggcgaaa cccgacagga ctataaagat 5100 accaggcgtt tccccctgga agctccctcg tgcgctctcc tgttccgacc ctgccgctta 5160 ccggatacct gtccgccttt ctcccttcgg gaagcgtggc gctttctcat agctcacgct 5220 gtaggtatct cagttcggtg taggtcgttc gctccaagct gggctgtgtg cacgaacccc 5280 ccgttcagcc cgaccgctgc gccttatccg gtaactatcg tcttgagtcc aacccggtaa 5340 gacacgactt atcgccactg gcagcagcca ctggtaacag gattagcaga gcgaggtatg 5400 taggcggtgc tacagagttc ttgaagtggt ggcctaacta cggctacact agaagaacag 5460 tatttggtat ctgcgctctg ctgaagccag ttaccttcgg aaaaagagtt ggtagctctt 5520 gatccggcaa acaaaccacc gctggtagcg gtggtttttt tgtttgcaag cagcagatta 5580 cgcgcagaaa aaaaggatct caagaagatc ctttgatctt ttctacgggg tctgacgctc 5640 agtggaacga aaactcacgt taagggattt tggtcatgag attatcaaaa aggatcttca 5700 cctagatcct tttaaattaa aaatgaagtt ttaaatcaat ctaaagtata tatgagtaaa 5760 cttggtctga cagttaccaa tgcttaatca gtgaggcacc tatctcagcg atctgtctat 5820 ttcgttcatc catagttgcc tgactccccg tcgtgtagat aactacgata cgggagggct 5880 taccatctgg ccccagtgct gcaatgatac cgcgagaccc acgctcaccg gctccagatt 5940 tatcagcaat aaaccagcca gccggaaggg ccgagcgcag aagtggtcct gcaactttat 6000 ccgcctccat ccagtctatt aattgttgcc gggaagctag agtaagtagt tcgccagtta 6060 atagtttgcg caacgttgtt gccattgcta caggcatcgt ggtgtcacgc tcgtcgtttg 6120 gtatggcttc attcagctcc ggttcccaac gatcaaggcg agttacatga tcccccatgt 6180 tgtgcaaaaa agcggttagc tccttcggtc ctccgatcgt tgtcagaagt aagttggccg 6240 cagtgttatc actcatggtt atggcagcac tgcataattc tcttactgtc atgccatccg 6300 taagatgctt ttctgtgact ggtgagtact caaccaagtc attctgagaa tagtgtatgc 6360 ggcgaccgag ttgctcttgc ccggcgtcaa tacgggataa taccgcgcca catagcagaa 6420 ctttaaaagt gctcatcatt ggaaaacgtt cttcggggcg aaaactctca aggatcttac 6480 cgctgttgag atccagttcg atgtaaccca ctcgtgcacc caactgatct tcagcatctt 6540 ttactttcac cagcgtttct gggtgagcaa aaacaggaag gcaaaatgcc gcaaaaaagg 6600 gaataagggc gacacggaaa tgttgaatac tcatactctt cctttttcaa tattattgaa 6660 gcatttatca gggttattgt ctcatgagcg gatacatatt tgaatgtatt tagaaaaata 6720 aacaaatagg ggttccgcgc acatttcccc gaaaagtgcc ac 6762