LISTADO DE SECUENCIAS <110> Valneva Austria GmbH Dynavax Technologies Corporation <120> VACUNA CONTRA EL VIRUS SARS-CoV-2 CON ADYUVANTE CpG <130> P6141WO00 <150> US 62983737 <151> 2020-03-01 <150> EP 20168324.0 <151> 2020-04-06 <150> EP 20202124.2 <151> 2020-10-15 <150> EP 20211936.8 <151> 2020-12-04 <150> EP 21154645.2 <151> 2021-02-01 <150> EP 21160933.4 <151> 2021-03-05 <150> US 21/20313 <151> 2021-03-01 <160> 32 <170> PatentIn versión 3.5 <210> 1 <211> 29903 <212> ADN <213> SARS-CoV2 <400> 1 attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct 60 gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact 120 cacgcagtat aattaataac taattactgt cgttgacagg acacgagtaa ctcgtctatc 180 ttctgcaggc tgcttacggt ttcgtccgtg ttgcagccga tcatcagcac atctaggttt 240 cgtccgggtg tgaccgaaag gtaagatgga gagccttgtc cctggtttca acgagaaaac 300 acacgtccaa ctcagtttgc ctgttttaca ggttcgcgac gtgctcgtac gtggctttgg 360 agactccgtg gaggaggtct tatcagaggc acgtcaacat cttaaagatg gcacttgtgg 420 cttagtagaa gttgaaaaag gcgttttgcc tcaacttgaa cagccctatg tgttcatcaa 480 acgttcggat gctcgaactg cacctcatgg tcatgttatg gttgagctgg tagcagaact 540 cgaaggcatt cagtacggtc gtagtggtga gacacttggt gtccttgtcc ctcatgtggg 600 cgaaatacca gtggcttacc gcaaggttct tcttcgtaag aacggtaata aaggagctgg 660 tggccatagt tacggcgccg atctaaagtc atttgactta ggcgacgagc ttggcactga 720 tccttatgaa gattttcaag aaaactggaa cactaaacat agcagtggtg ttacccgtga 780 actcatgcgt gagcttaacg gaggggcata cactcgctat gtcgataaca acttctgtgg 840 ccctgatggc taccctcttg agtgcattaa agaccttcta gcacgtgctg gtaaagcttc 900 atgcactttg tccgaacaac tggactttat tgacactaag aggggtgtat actgctgccg 960 tgaacatgag catgaaattg cttggtacac ggaacgttct gaaaagagct atgaattgca 1020 gacacctttt gaaattaaat tggcaaagaa atttgacacc ttcaatgggg aatgtccaaa 1080 ttttgtattt cccttaaatt ccataatcaa gactattcaa ccaagggttg aaaagaaaaa 1140 gcttgatggc tttatgggta gaattcgatc tgtctatcca gttgcgtcac caaatgaatg 1200 caaccaaatg tgcctttcaa ctctcatgaa gtgtgatcat tgtggtgaaa cttcatggca 1260 gacgggcgat tttgttaaag ccacttgcga attttgtggc actgagaatt tgactaaaga 1320 aggtgccact acttgtggtt acttacccca aaatgctgtt gttaaaattt attgtccagc 1380 atgtcacaat tcagaagtag gacctgagca tagtcttgcc gaataccata atgaatctgg 1440 cttgaaaacc attcttcgta agggtggtcg cactattgcc tttggaggct gtgtgttctc 1500 ttatgttggt tgccataaca agtgtgccta ttgggttcca cgtgctagcg ctaacatagg 1560 ttgtaaccat acaggtgttg ttggagaagg ttccgaaggt cttaatgaca accttcttga 1620 aatactccaa aaagagaaag tcaacatcaa tattgttggt gactttaaac ttaatgaaga 1680 gatcgccatt attttggcat ctttttctgc ttccacaagt gcttttgtgg aaactgtgaa 1740 aggtttggat tataaagcat tcaaacaaat tgttgaatcc tgtggtaatt ttaaagttac 1800 aaaaggaaaa gctaaaaaag gtgcctggaa tattggtgaa cagaaatcaa tactgagtcc 1860 tctttatgca tttgcatcag aggctgctcg tgttgtacga tcaattttct cccgcactct 1920 tgaaactgct caaaattctg tgcgtgtttt acagaaggcc gctataacaa tactagatgg 1980 aatttcacag tattcactga gactcattga tgctatgatg ttcacatctg atttggctac 2040 taacaatcta gttgtaatgg cctacattac aggtggtgtt gttcagttga cttcgcagtg 2100 gctaactaac atctttggca ctgtttatga aaaactcaaa cccgtccttg attggcttga 2160 agagaagttt aaggaaggtg tagagtttct tagagacggt tgggaaattg ttaaatttat 2220 ctcaacctgt gcttgtgaaa ttgtcggtgg acaaattgtc acctgtgcaa aggaaattaa 2280 ggagagtgtt cagacattct ttaagcttgt aaataaattt ttggctttgt gtgctgactc 2340 tatcattatt ggtggagcta aacttaaagc cttgaattta ggtgaaacat ttgtcacgca 2400 ctcaaaggga ttgtacagaa agtgtgttaa atccagagaa gaaactggcc tactcatgcc 2460 tctaaaagcc ccaaaagaaa ttatcttctt agagggagaa acacttccca cagaagtgtt 2520 aacagaggaa gttgtcttga aaactggtga tttacaacca ttagaacaac ctactagtga 2580 agctgttgaa gctccattgg ttggtacacc agtttgtatt aacgggctta tgttgctcga 2640 aatcaaagac acagaaaagt actgtgccct tgcacctaat atgatggtaa caaacaatac 2700 cttcacactc aaaggcggtg caccaacaaa ggttactttt ggtgatgaca ctgtgataga 2760 agtgcaaggt tacaagagtg tgaatatcac ttttgaactt gatgaaagga ttgataaagt 2820 acttaatgag aagtgctctg cctatacagt tgaactcggt acagaagtaa atgagttcgc 2880 ctgtgttgtg gcagatgctg tcataaaaac tttgcaacca gtatctgaat tacttacacc 2940 actgggcatt gatttagatg agtggagtat ggctacatac tacttatttg atgagtctgg 3000 tgagtttaaa ttggcttcac atatgtattg ttctttctac cctccagatg aggatgaaga 3060 agaaggtgat tgtgaagaag aagagtttga gccatcaact caatatgagt atggtactga 3120 agatgattac caaggtaaac ctttggaatt tggtgccact tctgctgctc ttcaacctga 3180 agaagagcaa gaagaagatt ggttagatga tgatagtcaa caaactgttg gtcaacaaga 3240 cggcagtgag gacaatcaga caactactat tcaaacaatt gttgaggttc aacctcaatt 3300 agagatggaa cttacaccag ttgttcagac tattgaagtg aatagtttta gtggttattt 3360 aaaacttact gacaatgtat acattaaaaa tgcagacatt gtggaagaag ctaaaaaggt 3420 aaaaccaaca gtggttgtta atgcagccaa tgtttacctt aaacatggag gaggtgttgc 3480 aggagcctta aataaggcta ctaacaatgc catgcaagtt gaatctgatg attacatagc 3540 tactaatgga ccacttaaag tgggtggtag ttgtgtttta agcggacaca atcttgctaa 3600 acactgtctt catgttgtcg gcccaaatgt taacaaaggt gaagacattc aacttcttaa 3660 gagtgcttat gaaaatttta atcagcacga agttctactt gcaccattat tatcagctgg 3720 tatttttggt gctgacccta tacattcttt aagagtttgt gtagatactg ttcgcacaaa 3780 tgtctactta gctgtctttg ataaaaatct ctatgacaaa cttgtttcaa gctttttgga 3840 aatgaagagt gaaaagcaag ttgaacaaaa gatcgctgag attcctaaag aggaagttaa 3900 gccatttata actgaaagta aaccttcagt tgaacagaga aaacaagatg ataagaaaat 3960 caaagcttgt gttgaagaag ttacaacaac tctggaagaa actaagttcc tcacagaaaa 4020 cttgttactt tatattgaca ttaatggcaa tcttcatcca gattctgcca ctcttgttag 4080 tgacattgac atcactttct taaagaaaga tgctccatat atagtgggtg atgttgttca 4140 agagggtgtt ttaactgctg tggttatacc tactaaaaag gctggtggca ctactgaaat 4200 gctagcgaaa gctttgagaa aagtgccaac agacaattat ataaccactt acccgggtca 4260 gggtttaaat ggttacactg tagaggaggc aaagacagtg cttaaaaagt gtaaaagtgc 4320 cttttacatt ctaccatcta ttatctctaa tgagaagcaa gaaattcttg gaactgtttc 4380 ttggaatttg cgagaaatgc ttgcacatgc agaagaaaca cgcaaattaa tgcctgtctg 4440 tgtggaaact aaagccatag tttcaactat acagcgtaaa tataagggta ttaaaataca 4500 agagggtgtg gttgattatg gtgctagatt ttacttttac accagtaaaa caactgtagc 4560 gtcacttatc aacacactta acgatctaaa tgaaactctt gttacaatgc cacttggcta 4620 tgtaacacat ggcttaaatt tggaagaagc tgctcggtat atgagatctc tcaaagtgcc 4680 agctacagtt tctgtttctt cacctgatgc tgttacagcg tataatggtt atcttacttc 4740 ttcttctaaa acacctgaag aacattttat tgaaaccatc tcacttgctg gttcctataa 4800 agattggtcc tattctggac aatctacaca actaggtata gaatttctta agagaggtga 4860 taaaagtgta tattacacta gtaatcctac cacattccac ctagatggtg aagttatcac 4920 ctttgacaat cttaagacac ttctttcttt gagagaagtg aggactatta aggtgtttac 4980 aacagtagac aacattaacc tccacacgca agttgtggac atgtcaatga catatggaca 5040 acagtttggt ccaacttatt tggatggagc tgatgttact aaaataaaac ctcataattc 5100 acatgaaggt aaaacatttt atgttttacc taatgatgac actctacgtg ttgaggcttt 5160 tgagtactac cacacaactg atcctagttt tctgggtagg tacatgtcag cattaaatca 5220 cactaaaaag tggaaatacc cacaagttaa tggtttaact tctattaaat gggcagataa 5280 caactgttat cttgccactg cattgttaac actccaacaa atagagttga agtttaatcc 5340 acctgctcta caagatgctt attacagagc aagggctggt gaagctgcta acttttgtgc 5400 acttatctta gcctactgta ataagacagt aggtgagtta ggtgatgtta gagaaacaat 5460 gagttacttg tttcaacatg ccaatttaga ttcttgcaaa agagtcttga acgtggtgtg 5520 taaaacttgt ggacaacagc agacaaccct taagggtgta gaagctgtta tgtacatggg 5580 cacactttct tatgaacaat ttaagaaagg tgttcagata ccttgtacgt gtggtaaaca 5640 agctacaaaa tatctagtac aacaggagtc accttttgtt atgatgtcag caccacctgc 5700 tcagtatgaa cttaagcatg gtacatttac ttgtgctagt gagtacactg gtaattacca 5760 gtgtggtcac tataaacata taacttctaa agaaactttg tattgcatag acggtgcttt 5820 acttacaaag tcctcagaat acaaaggtcc tattacggat gttttctaca aagaaaacag 5880 ttacacaaca accataaaac cagttactta taaattggat ggtgttgttt gtacagaaat 5940 tgaccctaag ttggacaatt attataagaa agacaattct tatttcacag agcaaccaat 6000 tgatcttgta ccaaaccaac catatccaaa cgcaagcttc gataatttta agtttgtatg 6060 tgataatatc aaatttgctg atgatttaaa ccagttaact ggttataaga aacctgcttc 6120 aagagagctt aaagttacat ttttccctga cttaaatggt gatgtggtgg ctattgatta 6180 taaacactac acaccctctt ttaagaaagg agctaaattg ttacataaac ctattgtttg 6240 gcatgttaac aatgcaacta ataaagccac gtataaacca aatacctggt gtatacgttg 6300 tctttggagc acaaaaccag ttgaaacatc aaattcgttt gatgtactga agtcagagga 6360 cgcgcaggga atggataatc ttgcctgcga agatctaaaa ccagtctctg aagaagtagt 6420 ggaaaatcct accatacaga aagacgttct tgagtgtaat gtgaaaacta ccgaagttgt 6480 aggagacatt atacttaaac cagcaaataa tagtttaaaa attacagaag aggttggcca 6540 cacagatcta atggctgctt atgtagacaa ttctagtctt actattaaga aacctaatga 6600 attatctaga gtattaggtt tgaaaaccct tgctactcat ggtttagctg ctgttaatag 6660 tgtcccttgg gatactatag ctaattatgc taagcctttt cttaacaaag ttgttagtac 6720 aactactaac atagttacac ggtgtttaaa ccgtgtttgt actaattata tgccttattt 6780 ctttacttta ttgctacaat tgtgtacttt tactagaagt acaaattcta gaattaaagc 6840 atctatgccg actactatag caaagaatac tgttaagagt gtcggtaaat tttgtctaga 6900 ggcttcattt aattatttga agtcacctaa tttttctaaa ctgataaata ttataatttg 6960 gtttttacta ttaagtgttt gcctaggttc tttaatctac tcaaccgctg ctttaggtgt 7020 tttaatgtct aatttaggca tgccttctta ctgtactggt tacagagaag gctatttgaa 7080 ctctactaat gtcactattg caacctactg tactggttct ataccttgta gtgtttgtct 7140 tagtggttta gattctttag acacctatcc ttctttagaa actatacaaa ttaccatttc 7200 atcttttaaa tgggatttaa ctgcttttgg cttagttgca gagtggtttt tggcatatat 7260 tcttttcact aggtttttct atgtacttgg attggctgca atcatgcaat tgtttttcag 7320 ctattttgca gtacatttta ttagtaattc ttggcttatg tggttaataa ttaatcttgt 7380 acaaatggcc ccgatttcag ctatggttag aatgtacatc ttctttgcat cattttatta 7440 tgtatggaaa agttatgtgc atgttgtaga cggttgtaat tcatcaactt gtatgatgtg 7500 ttacaaacgt aatagagcaa caagagtcga atgtacaact attgttaatg gtgttagaag 7560 gtccttttat gtctatgcta atggaggtaa aggcttttgc aaactacaca attggaattg 7620 tgttaattgt gatacattct gtgctggtag tacatttatt agtgatgaag ttgcgagaga 7680 cttgtcacta cagtttaaaa gaccaataaa tcctactgac cagtcttctt acatcgttga 7740 tagtgttaca gtgaagaatg gttccatcca tctttacttt gataaagctg gtcaaaagac 7800 ttatgaaaga cattctctct ctcattttgt taacttagac aacctgagag ctaataacac 7860 taaaggttca ttgcctatta atgttatagt ttttgatggt aaatcaaaat gtgaagaatc 7920 atctgcaaaa tcagcgtctg tttactacag tcagcttatg tgtcaaccta tactgttact 7980 agatcaggca ttagtgtctg atgttggtga tagtgcggaa gttgcagtta aaatgtttga 8040 tgcttacgtt aatacgtttt catcaacttt taacgtacca atggaaaaac tcaaaacact 8100 agttgcaact gcagaagctg aacttgcaaa gaatgtgtcc ttagacaatg tcttatctac 8160 ttttatttca gcagctcggc aagggtttgt tgattcagat gtagaaacta aagatgttgt 8220 tgaatgtctt aaattgtcac atcaatctga catagaagtt actggcgata gttgtaataa 8280 ctatatgctc acctataaca aagttgaaaa catgacaccc cgtgaccttg gtgcttgtat 8340 tgactgtagt gcgcgtcata ttaatgcgca ggtagcaaaa agtcacaaca ttgctttgat 8400 atggaacgtt aaagatttca tgtcattgtc tgaacaacta cgaaaacaaa tacgtagtgc 8460 tgctaaaaag aataacttac cttttaagtt gacatgtgca actactagac aagttgttaa 8520 tgttgtaaca acaaagatag cacttaaggg tggtaaaatt gttaataatt ggttgaagca 8580 gttaattaaa gttacacttg tgttcctttt tgttgctgct attttctatt taataacacc 8640 tgttcatgtc atgtctaaac atactgactt ttcaagtgaa atcataggat acaaggctat 8700 tgatggtggt gtcactcgtg acatagcatc tacagatact tgttttgcta acaaacatgc 8760 tgattttgac acatggttta gccagcgtgg tggtagttat actaatgaca aagcttgccc 8820 attgattgct gcagtcataa caagagaagt gggttttgtc gtgcctggtt tgcctggcac 8880 gatattacgc acaactaatg gtgacttttt gcatttctta cctagagttt ttagtgcagt 8940 tggtaacatc tgttacacac catcaaaact tatagagtac actgactttg caacatcagc 9000 ttgtgttttg gctgctgaat gtacaatttt taaagatgct tctggtaagc cagtaccata 9060 ttgttatgat accaatgtac tagaaggttc tgttgcttat gaaagtttac gccctgacac 9120 acgttatgtg ctcatggatg gctctattat tcaatttcct aacacctacc ttgaaggttc 9180 tgttagagtg gtaacaactt ttgattctga gtactgtagg cacggcactt gtgaaagatc 9240 agaagctggt gtttgtgtat ctactagtgg tagatgggta cttaacaatg attattacag 9300 atctttacca ggagttttct gtggtgtaga tgctgtaaat ttacttacta atatgtttac 9360 accactaatt caacctattg gtgctttgga catatcagca tctatagtag ctggtggtat 9420 tgtagctatc gtagtaacat gccttgccta ctattttatg aggtttagaa gagcttttgg 9480 tgaatacagt catgtagttg cctttaatac tttactattc cttatgtcat tcactgtact 9540 ctgtttaaca ccagtttact cattcttacc tggtgtttat tctgttattt acttgtactt 9600 gacattttat cttactaatg atgtttcttt tttagcacat attcagtgga tggttatgtt 9660 cacaccttta gtacctttct ggataacaat tgcttatatc atttgtattt ccacaaagca 9720 tttctattgg ttctttagta attacctaaa gagacgtgta gtctttaatg gtgtttcctt 9780 tagtactttt gaagaagctg cgctgtgcac ctttttgtta aataaagaaa tgtatctaaa 9840 gttgcgtagt gatgtgctat tacctcttac gcaatataat agatacttag ctctttataa 9900 taagtacaag tattttagtg gagcaatgga tacaactagc tacagagaag ctgcttgttg 9960 tcatctcgca aaggctctca atgacttcag taactcaggt tctgatgttc tttaccaacc 10020 accacaaacc tctatcacct cagctgtttt gcagagtggt tttagaaaaa tggcattccc 10080 atctggtaaa gttgagggtt gtatggtaca agtaacttgt ggtacaacta cacttaacgg 10140 tctttggctt gatgacgtag tttactgtcc aagacatgtg atctgcacct ctgaagacat 10200 gcttaaccct aattatgaag atttactcat tcgtaagtct aatcataatt tcttggtaca 10260 ggctggtaat gttcaactca gggttattgg acattctatg caaaattgtg tacttaagct 10320 taaggttgat acagccaatc ctaagacacc taagtataag tttgttcgca ttcaaccagg 10380 acagactttt tcagtgttag cttgttacaa tggttcacca tctggtgttt accaatgtgc 10440 tatgaggccc aatttcacta ttaagggttc attccttaat ggttcatgtg gtagtgttgg 10500 ttttaacata gattatgact gtgtctcttt ttgttacatg caccatatgg aattaccaac 10560 tggagttcat gctggcacag acttagaagg taacttttat ggaccttttg ttgacaggca 10620 aacagcacaa gcagctggta cggacacaac tattacagtt aatgttttag cttggttgta 10680 cgctgctgtt ataaatggag acaggtggtt tctcaatcga tttaccacaa ctcttaatga 10740 ctttaacctt gtggctatga agtacaatta tgaacctcta acacaagacc atgttgacat 10800 actaggacct ctttctgctc aaactggaat tgccgtttta gatatgtgtg cttcattaaa 10860 agaattactg caaaatggta tgaatggacg taccatattg ggtagtgctt tattagaaga 10920 tgaatttaca ccttttgatg ttgttagaca atgctcaggt gttactttcc aaagtgcagt 10980 gaaaagaaca atcaagggta cacaccactg gttgttactc acaattttga cttcactttt 11040 agttttagtc cagagtactc aatggtcttt gttctttttt ttgtatgaaa atgccttttt 11100 accttttgct atgggtatta ttgctatgtc tgcttttgca atgatgtttg tcaaacataa 11160 gcatgcattt ctctgtttgt ttttgttacc ttctcttgcc actgtagctt attttaatat 11220 ggtctatatg cctgctagtt gggtgatgcg tattatgaca tggttggata tggttgatac 11280 tagtttgtct ggttttaagc taaaagactg tgttatgtat gcatcagctg tagtgttact 11340 aatccttatg acagcaagaa ctgtgtatga tgatggtgct aggagagtgt ggacacttat 11400 gaatgtcttg acactcgttt ataaagttta ttatggtaat gctttagatc aagccatttc 11460 catgtgggct cttataatct ctgttacttc taactactca ggtgtagtta caactgtcat 11520 gtttttggcc agaggtattg tttttatgtg tgttgagtat tgccctattt tcttcataac 11580 tggtaataca cttcagtgta taatgctagt ttattgtttc ttaggctatt tttgtacttg 11640 ttactttggc ctcttttgtt tactcaaccg ctactttaga ctgactcttg gtgtttatga 11700 ttacttagtt tctacacagg agtttagata tatgaattca cagggactac tcccacccaa 11760 gaatagcata gatgccttca aactcaacat taaattgttg ggtgttggtg gcaaaccttg 11820 tatcaaagta gccactgtac agtctaaaat gtcagatgta aagtgcacat cagtagtctt 11880 actctcagtt ttgcaacaac tcagagtaga atcatcatct aaattgtggg ctcaatgtgt 11940 ccagttacac aatgacattc tcttagctaa agatactact gaagcctttg aaaaaatggt 12000 ttcactactt tctgttttgc tttccatgca gggtgctgta gacataaaca agctttgtga 12060 agaaatgctg gacaacaggg caaccttaca agctatagcc tcagagttta gttcccttcc 12120 atcatatgca gcttttgcta ctgctcaaga agcttatgag caggctgttg ctaatggtga 12180 ttctgaagtt gttcttaaaa agttgaagaa gtctttgaat gtggctaaat ctgaatttga 12240 ccgtgatgca gccatgcaac gtaagttgga aaagatggct gatcaagcta tgacccaaat 12300 gtataaacag gctagatctg aggacaagag ggcaaaagtt actagtgcta tgcagacaat 12360 gcttttcact atgcttagaa agttggataa tgatgcactc aacaacatta tcaacaatgc 12420 aagagatggt tgtgttccct tgaacataat acctcttaca acagcagcca aactaatggt 12480 tgtcatacca gactataaca catataaaaa tacgtgtgat ggtacaacat ttacttatgc 12540 atcagcattg tgggaaatcc aacaggttgt agatgcagat agtaaaattg ttcaacttag 12600 tgaaattagt atggacaatt cacctaattt agcatggcct cttattgtaa cagctttaag 12660 ggccaattct gctgtcaaat tacagaataa tgagcttagt cctgttgcac tacgacagat 12720 gtcttgtgct gccggtacta cacaaactgc ttgcactgat gacaatgcgt tagcttacta 12780 caacacaaca aagggaggta ggtttgtact tgcactgtta tccgatttac aggatttgaa 12840 atgggctaga ttccctaaga gtgatggaac tggtactatc tatacagaac tggaaccacc 12900 ttgtaggttt gttacagaca cacctaaagg tcctaaagtg aagtatttat actttattaa 12960 aggattaaac aacctaaata gaggtatggt acttggtagt ttagctgcca cagtacgtct 13020 acaagctggt aatgcaacag aagtgcctgc caattcaact gtattatctt tctgtgcttt 13080 tgctgtagat gctgctaaag cttacaaaga ttatctagct agtgggggac aaccaatcac 13140 taattgtgtt aagatgttgt gtacacacac tggtactggt caggcaataa cagttacacc 13200 ggaagccaat atggatcaag aatcctttgg tggtgcatcg tgttgtctgt actgccgttg 13260 ccacatagat catccaaatc ctaaaggatt ttgtgactta aaaggtaagt atgtacaaat 13320 acctacaact tgtgctaatg accctgtggg ttttacactt aaaaacacag tctgtaccgt 13380 ctgcggtatg tggaaaggtt atggctgtag ttgtgatcaa ctccgcgaac ccatgcttca 13440 gtcagctgat gcacaatcgt ttttaaacgg gtttgcggtg taagtgcagc ccgtcttaca 13500 ccgtgcggca caggcactag tactgatgtc gtatacaggg cttttgacat ctacaatgat 13560 aaagtagctg gttttgctaa attcctaaaa actaattgtt gtcgcttcca agaaaaggac 13620 gaagatgaca atttaattga ttcttacttt gtagttaaga gacacacttt ctctaactac 13680 caacatgaag aaacaattta taatttactt aaggattgtc cagctgttgc taaacatgac 13740 ttctttaagt ttagaataga cggtgacatg gtaccacata tatcacgtca acgtcttact 13800 aaatacacaa tggcagacct cgtctatgct ttaaggcatt ttgatgaagg taattgtgac 13860 acattaaaag aaatacttgt cacatacaat tgttgtgatg atgattattt caataaaaag 13920 gactggtatg attttgtaga aaacccagat atattacgcg tatacgccaa cttaggtgaa 13980 cgtgtacgcc aagctttgtt aaaaacagta caattctgtg atgccatgcg aaatgctggt 14040 attgttggtg tactgacatt agataatcaa gatctcaatg gtaactggta tgatttcggt 14100 gatttcatac aaaccacgcc aggtagtgga gttcctgttg tagattctta ttattcattg 14160 ttaatgccta tattaacctt gaccagggct ttaactgcag agtcacatgt tgacactgac 14220 ttaacaaagc cttacattaa gtgggatttg ttaaaatatg acttcacgga agagaggtta 14280 aaactctttg accgttattt taaatattgg gatcagacat accacccaaa ttgtgttaac 14340 tgtttggatg acagatgcat tctgcattgt gcaaacttta atgttttatt ctctacagtg 14400 ttcccaccta caagttttgg accactagtg agaaaaatat ttgttgatgg tgttccattt 14460 gtagtttcaa ctggatacca cttcagagag ctaggtgttg tacataatca ggatgtaaac 14520 ttacatagct ctagacttag ttttaaggaa ttacttgtgt atgctgctga ccctgctatg 14580 cacgctgctt ctggtaatct attactagat aaacgcacta cgtgcttttc agtagctgca 14640 cttactaaca atgttgcttt tcaaactgtc aaacccggta attttaacaa agacttctat 14700 gactttgctg tgtctaaggg tttctttaag gaaggaagtt ctgttgaatt aaaacacttc 14760 ttctttgctc aggatggtaa tgctgctatc agcgattatg actactatcg ttataatcta 14820 ccaacaatgt gtgatatcag acaactacta tttgtagttg aagttgttga taagtacttt 14880 gattgttacg atggtggctg tattaatgct aaccaagtca tcgtcaacaa cctagacaaa 14940 tcagctggtt ttccatttaa taaatggggt aaggctagac tttattatga ttcaatgagt 15000 tatgaggatc aagatgcact tttcgcatat acaaaacgta atgtcatccc tactataact 15060 caaatgaatc ttaagtatgc cattagtgca aagaatagag ctcgcaccgt agctggtgtc 15120 tctatctgta gtactatgac caatagacag tttcatcaaa aattattgaa atcaatagcc 15180 gccactagag gagctactgt agtaattgga acaagcaaat tctatggtgg ttggcacaac 15240 atgttaaaaa ctgtttatag tgatgtagaa aaccctcacc ttatgggttg ggattatcct 15300 aaatgtgata gagccatgcc taacatgctt agaattatgg cctcacttgt tcttgctcgc 15360 aaacatacaa cgtgttgtag cttgtcacac cgtttctata gattagctaa tgagtgtgct 15420 caagtattga gtgaaatggt catgtgtggc ggttcactat atgttaaacc aggtggaacc 15480 tcatcaggag atgccacaac tgcttatgct aatagtgttt ttaacatttg tcaagctgtc 15540 acggccaatg ttaatgcact tttatctact gatggtaaca aaattgccga taagtatgtc 15600 cgcaatttac aacacagact ttatgagtgt ctctatagaa atagagatgt tgacacagac 15660 tttgtgaatg agttttacgc atatttgcgt aaacatttct caatgatgat actctctgac 15720 gatgctgttg tgtgtttcaa tagcacttat gcatctcaag gtctagtggc tagcataaag 15780 aactttaagt cagttcttta ttatcaaaac aatgttttta tgtctgaagc aaaatgttgg 15840 actgagactg accttactaa aggacctcat gaattttgct ctcaacatac aatgctagtt 15900 aaacagggtg atgattatgt gtaccttcct tacccagatc catcaagaat cctaggggcc 15960 ggctgttttg tagatgatat cgtaaaaaca gatggtacac ttatgattga acggttcgtg 16020 tctttagcta tagatgctta cccacttact aaacatccta atcaggagta tgctgatgtc 16080 tttcatttgt acttacaata cataagaaag ctacatgatg agttaacagg acacatgtta 16140 gacatgtatt ctgttatgct tactaatgat aacacttcaa ggtattggga acctgagttt 16200 tatgaggcta tgtacacacc gcatacagtc ttacaggctg ttggggcttg tgttctttgc 16260 aattcacaga cttcattaag atgtggtgct tgcatacgta gaccattctt atgttgtaaa 16320 tgctgttacg accatgtcat atcaacatca cataaattag tcttgtctgt taatccgtat 16380 gtttgcaatg ctccaggttg tgatgtcaca gatgtgactc aactttactt aggaggtatg 16440 agctattatt gtaaatcaca taaaccaccc attagttttc cattgtgtgc taatggacaa 16500 gtttttggtt tatataaaaa tacatgtgtt ggtagcgata atgttactga ctttaatgca 16560 attgcaacat gtgactggac aaatgctggt gattacattt tagctaacac ctgtactgaa 16620 agactcaagc tttttgcagc agaaacgctc aaagctactg aggagacatt taaactgtct 16680 tatggtattg ctactgtacg tgaagtgctg tctgacagag aattacatct ttcatgggaa 16740 gttggtaaac ctagaccacc acttaaccga aattatgtct ttactggtta tcgtgtaact 16800 aaaaacagta aagtacaaat aggagagtac acctttgaaa aaggtgacta tggtgatgct 16860 gttgtttacc gaggtacaac aacttacaaa ttaaatgttg gtgattattt tgtgctgaca 16920 tcacatacag taatgccatt aagtgcacct acactagtgc cacaagagca ctatgttaga 16980 attactggct tatacccaac actcaatatc tcagatgagt tttctagcaa tgttgcaaat 17040 tatcaaaagg ttggtatgca aaagtattct acactccagg gaccacctgg tactggtaag 17100 agtcattttg ctattggcct agctctctac tacccttctg ctcgcatagt gtatacagct 17160 tgctctcatg ccgctgttga tgcactatgt gagaaggcat taaaatattt gcctatagat 17220 aaatgtagta gaattatacc tgcacgtgct cgtgtagagt gttttgataa attcaaagtg 17280 aattcaacat tagaacagta tgtcttttgt actgtaaatg cattgcctga gacgacagca 17340 gatatagttg tctttgatga aatttcaatg gccacaaatt atgatttgag tgttgtcaat 17400 gccagattac gtgctaagca ctatgtgtac attggcgacc ctgctcaatt acctgcacca 17460 cgcacattgc taactaaggg cacactagaa ccagaatatt tcaattcagt gtgtagactt 17520 atgaaaacta taggtccaga catgttcctc ggaacttgtc ggcgttgtcc tgctgaaatt 17580 gttgacactg tgagtgcttt ggtttatgat aataagctta aagcacataa agacaaatca 17640 gctcaatgct ttaaaatgtt ttataagggt gttatcacgc atgatgtttc atctgcaatt 17700 aacaggccac aaataggcgt ggtaagagaa ttccttacac gtaaccctgc ttggagaaaa 17760 gctgtcttta tttcacctta taattcacag aatgctgtag cctcaaagat tttgggacta 17820 ccaactcaaa ctgttgattc atcacagggc tcagaatatg actatgtcat attcactcaa 17880 accactgaaa cagctcactc ttgtaatgta aacagattta atgttgctat taccagagca 17940 aaagtaggca tactttgcat aatgtctgat agagaccttt atgacaagtt gcaatttaca 18000 agtcttgaaa ttccacgtag gaatgtggca actttacaag ctgaaaatgt aacaggactc 18060 tttaaagatt gtagtaaggt aatcactggg ttacatccta cacaggcacc tacacacctc 18120 agtgttgaca ctaaattcaa aactgaaggt ttatgtgttg acatacctgg catacctaag 18180 gacatgacct atagaagact catctctatg atgggtttta aaatgaatta tcaagttaat 18240 ggttacccta acatgtttat cacccgcgaa gaagctataa gacatgtacg tgcatggatt 18300 ggcttcgatg tcgaggggtg tcatgctact agagaagctg ttggtaccaa tttaccttta 18360 cagctaggtt tttctacagg tgttaaccta gttgctgtac ctacaggtta tgttgataca 18420 cctaataata cagatttttc cagagttagt gctaaaccac cgcctggaga tcaatttaaa 18480 cacctcatac cacttatgta caaaggactt ccttggaatg tagtgcgtat aaagattgta 18540 caaatgttaa gtgacacact taaaaatctc tctgacagag tcgtatttgt cttatgggca 18600 catggctttg agttgacatc tatgaagtat tttgtgaaaa taggacctga gcgcacctgt 18660 tgtctatgtg atagacgtgc cacatgcttt tccactgctt cagacactta tgcctgttgg 18720 catcattcta ttggatttga ttacgtctat aatccgttta tgattgatgt tcaacaatgg 18780 ggttttacag gtaacctaca aagcaaccat gatctgtatt gtcaagtcca tggtaatgca 18840 catgtagcta gttgtgatgc aatcatgact aggtgtctag ctgtccacga gtgctttgtt 18900 aagcgtgttg actggactat tgaatatcct ataattggtg atgaactgaa gattaatgcg 18960 gcttgtagaa aggttcaaca catggttgtt aaagctgcat tattagcaga caaattccca 19020 gttcttcacg acattggtaa ccctaaagct attaagtgtg tacctcaagc tgatgtagaa 19080 tggaagttct atgatgcaca gccttgtagt gacaaagctt ataaaataga agaattattc 19140 tattcttatg ccacacattc tgacaaattc acagatggtg tatgcctatt ttggaattgc 19200 aatgtcgata gatatcctgc taattccatt gtttgtagat ttgacactag agtgctatct 19260 aaccttaact tgcctggttg tgatggtggc agtttgtatg taaataaaca tgcattccac 19320 acaccagctt ttgataaaag tgcttttgtt aatttaaaac aattaccatt tttctattac 19380 tctgacagtc catgtgagtc tcatggaaaa caagtagtgt cagatataga ttatgtacca 19440 ctaaagtctg ctacgtgtat aacacgttgc aatttaggtg gtgctgtctg tagacatcat 19500 gctaatgagt acagattgta tctcgatgct tataacatga tgatctcagc tggctttagc 19560 ttgtgggttt acaaacaatt tgatacttat aacctctgga acacttttac aagacttcag 19620 agtttagaaa atgtggcttt taatgttgta aataagggac actttgatgg acaacagggt 19680 gaagtaccag tttctatcat taataacact gtttacacaa aagttgatgg tgttgatgta 19740 gaattgtttg aaaataaaac aacattacct gttaatgtag catttgagct ttgggctaag 19800 cgcaacatta aaccagtacc agaggtgaaa atactcaata atttgggtgt ggacattgct 19860 gctaatactg tgatctggga ctacaaaaga gatgctccag cacatatatc tactattggt 19920 gtttgttcta tgactgacat agccaagaaa ccaactgaaa cgatttgtgc accactcact 19980 gtcttttttg atggtagagt tgatggtcaa gtagacttat ttagaaatgc ccgtaatggt 20040 gttcttatta cagaaggtag tgttaaaggt ttacaaccat ctgtaggtcc caaacaagct 20100 agtcttaatg gagtcacatt aattggagaa gccgtaaaaa cacagttcaa ttattataag 20160 aaagttgatg gtgttgtcca acaattacct gaaacttact ttactcagag tagaaattta 20220 caagaattta aacccaggag tcaaatggaa attgatttct tagaattagc tatggatgaa 20280 ttcattgaac ggtataaatt agaaggctat gccttcgaac atatcgttta tggagatttt 20340 agtcatagtc agttaggtgg tttacatcta ctgattggac tagctaaacg ttttaaggaa 20400 tcaccttttg aattagaaga ttttattcct atggacagta cagttaaaaa ctatttcata 20460 acagatgcgc aaacaggttc atctaagtgt gtgtgttctg ttattgattt attacttgat 20520 gattttgttg aaataataaa atcccaagat ttatctgtag tttctaaggt tgtcaaagtg 20580 actattgact atacagaaat ttcatttatg ctttggtgta aagatggcca tgtagaaaca 20640 ttttacccaa aattacaatc tagtcaagcg tggcaaccgg gtgttgctat gcctaatctt 20700 tacaaaatgc aaagaatgct attagaaaag tgtgaccttc aaaattatgg tgatagtgca 20760 acattaccta aaggcataat gatgaatgtc gcaaaatata ctcaactgtg tcaatattta 20820 aacacattaa cattagctgt accctataat atgagagtta tacattttgg tgctggttct 20880 gataaaggag ttgcaccagg tacagctgtt ttaagacagt ggttgcctac gggtacgctg 20940 cttgtcgatt cagatcttaa tgactttgtc tctgatgcag attcaacttt gattggtgat 21000 tgtgcaactg tacatacagc taataaatgg gatctcatta ttagtgatat gtacgaccct 21060 aagactaaaa atgttacaaa agaaaatgac tctaaagagg gttttttcac ttacatttgt 21120 gggtttatac aacaaaagct agctcttgga ggttccgtgg ctataaagat aacagaacat 21180 tcttggaatg ctgatcttta taagctcatg ggacacttcg catggtggac agcctttgtt 21240 actaatgtga atgcgtcatc atctgaagca tttttaattg gatgtaatta tcttggcaaa 21300 ccacgcgaac aaatagatgg ttatgtcatg catgcaaatt acatattttg gaggaataca 21360 aatccaattc agttgtcttc ctattcttta tttgacatga gtaaatttcc ccttaaatta 21420 aggggtactg ctgttatgtc tttaaaagaa ggtcaaatca atgatatgat tttatctctt 21480 cttagtaaag gtagacttat aattagagaa aacaacagag ttgttatttc tagtgatgtt 21540 cttgttaaca actaaacgaa caatgtttgt ttttcttgtt ttattgccac tagtctctag 21600 tcagtgtgtt aatcttacaa ccagaactca attaccccct gcatacacta attctttcac 21660 acgtggtgtt tattaccctg acaaagtttt cagatcctca gttttacatt caactcagga 21720 cttgttctta cctttctttt ccaatgttac ttggttccat gctatacatg tctctgggac 21780 caatggtact aagaggtttg ataaccctgt cctaccattt aatgatggtg tttattttgc 21840 ttccactgag aagtctaaca taataagagg ctggattttt ggtactactt tagattcgaa 21900 gacccagtcc ctacttattg ttaataacgc tactaatgtt gttattaaag tctgtgaatt 21960 tcaattttgt aatgatccat ttttgggtgt ttattaccac aaaaacaaca aaagttggat 22020 ggaaagtgag ttcagagttt attctagtgc gaataattgc acttttgaat atgtctctca 22080 gccttttctt atggaccttg aaggaaaaca gggtaatttc aaaaatctta gggaatttgt 22140 gtttaagaat attgatggtt attttaaaat atattctaag cacacgccta ttaatttagt 22200 gcgtgatctc cctcagggtt tttcggcttt agaaccattg gtagatttgc caataggtat 22260 taacatcact aggtttcaaa ctttacttgc tttacataga agttatttga ctcctggtga 22320 ttcttcttca ggttggacag ctggtgctgc agcttattat gtgggttatc ttcaacctag 22380 gacttttcta ttaaaatata atgaaaatgg aaccattaca gatgctgtag actgtgcact 22440 tgaccctctc tcagaaacaa agtgtacgtt gaaatccttc actgtagaaa aaggaatcta 22500 tcaaacttct aactttagag tccaaccaac agaatctatt gttagatttc ctaatattac 22560 aaacttgtgc ccttttggtg aagtttttaa cgccaccaga tttgcatctg tttatgcttg 22620 gaacaggaag agaatcagca actgtgttgc tgattattct gtcctatata attccgcatc 22680 attttccact tttaagtgtt atggagtgtc tcctactaaa ttaaatgatc tctgctttac 22740 taatgtctat gcagattcat ttgtaattag aggtgatgaa gtcagacaaa tcgctccagg 22800 gcaaactgga aagattgctg attataatta taaattacca gatgatttta caggctgcgt 22860 tatagcttgg aattctaaca atcttgattc taaggttggt ggtaattata attacctgta 22920 tagattgttt aggaagtcta atctcaaacc ttttgagaga gatatttcaa ctgaaatcta 22980 tcaggccggt agcacacctt gtaatggtgt tgaaggtttt aattgttact ttcctttaca 23040 atcatatggt ttccaaccca ctaatggtgt tggttaccaa ccatacagag tagtagtact 23100 ttcttttgaa cttctacatg caccagcaac tgtttgtgga cctaaaaagt ctactaattt 23160 ggttaaaaac aaatgtgtca atttcaactt caatggttta acaggcacag gtgttcttac 23220 tgagtctaac aaaaagtttc tgcctttcca acaatttggc agagacattg ctgacactac 23280 tgatgctgtc cgtgatccac agacacttga gattcttgac attacaccat gttcttttgg 23340 tggtgtcagt gttataacac caggaacaaa tacttctaac caggttgctg ttctttatca 23400 ggatgttaac tgcacagaag tccctgttgc tattcatgca gatcaactta ctcctacttg 23460 gcgtgtttat tctacaggtt ctaatgtttt tcaaacacgt gcaggctgtt taataggggc 23520 tgaacatgtc aacaactcat atgagtgtga catacccatt ggtgcaggta tatgcgctag 23580 ttatcagact cagactaatt ctcctcggcg ggcacgtagt gtagctagtc aatccatcat 23640 tgcctacact atgtcacttg gtgcagaaaa ttcagttgct tactctaata actctattgc 23700 catacccaca aattttacta ttagtgttac cacagaaatt ctaccagtgt ctatgaccaa 23760 gacatcagta gattgtacaa tgtacatttg tggtgattca actgaatgca gcaatctttt 23820 gttgcaatat ggcagttttt gtacacaatt aaaccgtgct ttaactggaa tagctgttga 23880 acaagacaaa aacacccaag aagtttttgc acaagtcaaa caaatttaca aaacaccacc 23940 aattaaagat tttggtggtt ttaatttttc acaaatatta ccagatccat caaaaccaag 24000 caagaggtca tttattgaag atctactttt caacaaagtg acacttgcag atgctggctt 24060 catcaaacaa tatggtgatt gccttggtga tattgctgct agagacctca tttgtgcaca 24120 aaagtttaac ggccttactg ttttgccacc tttgctcaca gatgaaatga ttgctcaata 24180 cacttctgca ctgttagcgg gtacaatcac ttctggttgg acctttggtg caggtgctgc 24240 attacaaata ccatttgcta tgcaaatggc ttataggttt aatggtattg gagttacaca 24300 gaatgttctc tatgagaacc aaaaattgat tgccaaccaa tttaatagtg ctattggcaa 24360 aattcaagac tcactttctt ccacagcaag tgcacttgga aaacttcaag atgtggtcaa 24420 ccaaaatgca caagctttaa acacgcttgt taaacaactt agctccaatt ttggtgcaat 24480 ttcaagtgtt ttaaatgata tcctttcacg tcttgacaaa gttgaggctg aagtgcaaat 24540 tgataggttg atcacaggca gacttcaaag tttgcagaca tatgtgactc aacaattaat 24600 tagagctgca gaaatcagag cttctgctaa tcttgctgct actaaaatgt cagagtgtgt 24660 acttggacaa tcaaaaagag ttgatttttg tggaaagggc tatcatctta tgtccttccc 24720 tcagtcagca cctcatggtg tagtcttctt gcatgtgact tatgtccctg cacaagaaaa 24780 gaacttcaca actgctcctg ccatttgtca tgatggaaaa gcacactttc ctcgtgaagg 24840 tgtctttgtt tcaaatggca cacactggtt tgtaacacaa aggaattttt atgaaccaca 24900 aatcattact acagacaaca catttgtgtc tggtaactgt gatgttgtaa taggaattgt 24960 caacaacaca gtttatgatc ctttgcaacc tgaattagac tcattcaagg aggagttaga 25020 taaatatttt aagaatcata catcaccaga tgttgattta ggtgacatct ctggcattaa 25080 tgcttcagtt gtaaacattc aaaaagaaat tgaccgcctc aatgaggttg ccaagaattt 25140 aaatgaatct ctcatcgatc tccaagaact tggaaagtat gagcagtata taaaatggcc 25200 atggtacatt tggctaggtt ttatagctgg cttgattgcc atagtaatgg tgacaattat 25260 gctttgctgt atgaccagtt gctgtagttg tctcaagggc tgttgttctt gtggatcctg 25320 ctgcaaattt gatgaagacg actctgagcc agtgctcaaa ggagtcaaat tacattacac 25380 ataaacgaac ttatggattt gtttatgaga atcttcacaa ttggaactgt aactttgaag 25440 caaggtgaaa tcaaggatgc tactccttca gattttgttc gcgctactgc aacgataccg 25500 atacaagcct cactcccttt cggatggctt attgttggcg ttgcacttct tgctgttttt 25560 cagagcgctt ccaaaatcat aaccctcaaa aagagatggc aactagcact ctccaagggt 25620 gttcactttg tttgcaactt gctgttgttg tttgtaacag tttactcaca ccttttgctc 25680 gttgctgctg gccttgaagc cccttttctc tatctttatg ctttagtcta cttcttgcag 25740 agtataaact ttgtaagaat aataatgagg ctttggcttt gctggaaatg ccgttccaaa 25800 aacccattac tttatgatgc caactatttt ctttgctggc atactaattg ttacgactat 25860 tgtatacctt acaatagtgt aacttcttca attgtcatta cttcaggtga tggcacaaca 25920 agtcctattt ctgaacatga ctaccagatt ggtggttata ctgaaaaatg ggaatctgga 25980 gtaaaagact gtgttgtatt acacagttac ttcacttcag actattacca gctgtactca 26040 actcaattga gtacagacac tggtgttgaa catgttacct tcttcatcta caataaaatt 26100 gttgatgagc ctgaagaaca tgtccaaatt cacacaatcg acggttcatc cggagttgtt 26160 aatccagtaa tggaaccaat ttatgatgaa ccgacgacga ctactagcgt gcctttgtaa 26220 gcacaagctg atgagtacga acttatgtac tcattcgttt cggaagagac aggtacgtta 26280 atagttaata gcgtacttct ttttcttgct ttcgtggtat tcttgctagt tacactagcc 26340 atccttactg cgcttcgatt gtgtgcgtac tgctgcaata ttgttaacgt gagtcttgta 26400 aaaccttctt tttacgttta ctctcgtgtt aaaaatctga attcttctag agttcctgat 26460 cttctggtct aaacgaacta aatattatat tagtttttct gtttggaact ttaattttag 26520 ccatggcaga ttccaacggt actattaccg ttgaagagct taaaaagctc cttgaacaat 26580 ggaacctagt aataggtttc ctattcctta catggatttg tcttctacaa tttgcctatg 26640 ccaacaggaa taggtttttg tatataatta agttaatttt cctctggctg ttatggccag 26700 taactttagc ttgttttgtg cttgctgctg tttacagaat aaattggatc accggtggaa 26760 ttgctatcgc aatggcttgt cttgtaggct tgatgtggct cagctacttc attgcttctt 26820 tcagactgtt tgcgcgtacg cgttccatgt ggtcattcaa tccagaaact aacattcttc 26880 tcaacgtgcc actccatggc actattctga ccagaccgct tctagaaagt gaactcgtaa 26940 tcggagctgt gatccttcgt ggacatcttc gtattgctgg acaccatcta ggacgctgtg 27000 acatcaagga cctgcctaaa gaaatcactg ttgctacatc acgaacgctt tcttattaca 27060 aattgggagc ttcgcagcgt gtagcaggtg actcaggttt tgctgcatac agtcgctaca 27120 ggattggcaa ctataaatta aacacagacc attccagtag cagtgacaat attgctttgc 27180 ttgtacagta agtgacaaca gatgtttcat ctcgttgact ttcaggttac tatagcagag 27240 atattactaa ttattatgag gacttttaaa gtttccattt ggaatcttga ttacatcata 27300 aacctcataa ttaaaaattt atctaagtca ctaactgaga ataaatattc tcaattagat 27360 gaagagcaac caatggagat tgattaaacg aacatgaaaa ttattctttt cttggcactg 27420 ataacactcg ctacttgtga gctttatcac taccaagagt gtgttagagg tacaacagta 27480 cttttaaaag aaccttgctc ttctggaaca tacgagggca attcaccatt tcatcctcta 27540 gctgataaca aatttgcact gacttgcttt agcactcaat ttgcttttgc ttgtcctgac 27600 ggcgtaaaac acgtctatca gttacgtgcc agatcagttt cacctaaact gttcatcaga 27660 caagaggaag ttcaagaact ttactctcca atttttctta ttgttgcggc aatagtgttt 27720 ataacacttt gcttcacact caaaagaaag acagaatgat tgaactttca ttaattgact 27780 tctatttgtg ctttttagcc tttctgctat tccttgtttt aattatgctt attatctttt 27840 ggttctcact tgaactgcaa gatcataatg aaacttgtca cgcctaaacg aacatgaaat 27900 ttcttgtttt cttaggaatc atcacaactg tagctgcatt tcaccaagaa tgtagtttac 27960 agtcatgtac tcaacatcaa ccatatgtag ttgatgaccc gtgtcctatt cacttctatt 28020 ctaaatggta tattagagta ggagctagaa aatcagcacc tttaattgaa ttgtgcgtgg 28080 atgaggctgg ttctaaatca cccattcagt acatcgatat cggtaattat acagtttcct 28140 gtttaccttt tacaattaat tgccaggaac ctaaattggg tagtcttgta gtgcgttgtt 28200 cgttctatga agacttttta gagtatcatg acgttcgtgt tgttttagat ttcatctaaa 28260 cgaacaaact aaaatgtctg ataatggacc ccaaaatcag cgaaatgcac cccgcattac 28320 gtttggtgga ccctcagatt caactggcag taaccagaat ggagaacgca gtggggcgcg 28380 atcaaaacaa cgtcggcccc aaggtttacc caataatact gcgtcttggt tcaccgctct 28440 cactcaacat ggcaaggaag accttaaatt ccctcgagga caaggcgttc caattaacac 28500 caatagcagt ccagatgacc aaattggcta ctaccgaaga gctaccagac gaattcgtgg 28560 tggtgacggt aaaatgaaag atctcagtcc aagatggtat ttctactacc taggaactgg 28620 gccagaagct ggacttccct atggtgctaa caaagacggc atcatatggg ttgcaactga 28680 gggagccttg aatacaccaa aagatcacat tggcacccgc aatcctgcta acaatgctgc 28740 aatcgtgcta caacttcctc aaggaacaac attgccaaaa ggcttctacg cagaagggag 28800 cagaggcggc agtcaagcct cttctcgttc ctcatcacgt agtcgcaaca gttcaagaaa 28860 ttcaactcca ggcagcagta ggggaacttc tcctgctaga atggctggca atggcggtga 28920 tgctgctctt gctttgctgc tgcttgacag attgaaccag cttgagagca aaatgtctgg 28980 taaaggccaa caacaacaag gccaaactgt cactaagaaa tctgctgctg aggcttctaa 29040 gaagcctcgg caaaaacgta ctgccactaa agcatacaat gtaacacaag ctttcggcag 29100 acgtggtcca gaacaaaccc aaggaaattt tggggaccag gaactaatca gacaaggaac 29160 tgattacaaa cattggccgc aaattgcaca atttgccccc agcgcttcag cgttcttcgg 29220 aatgtcgcgc attggcatgg aagtcacacc ttcgggaacg tggttgacct acacaggtgc 29280 catcaaattg gatgacaaag atccaaattt caaagatcaa gtcattttgc tgaataagca 29340 tattgacgca tacaaaacat tcccaccaac agagcctaaa aaggacaaaa agaagaaggc 29400 tgatgaaact caagccttac cgcagagaca gaagaaacag caaactgtga ctcttcttcc 29460 tgctgcagat ttggatgatt tctccaaaca attgcaacaa tccatgagca gtgctgactc 29520 aactcaggcc taaactcatg cagaccacac aaggcagatg ggctatataa acgttttcgc 29580 ttttccgttt acgatatata gtctactctt gtgcagaatg aattctcgta actacatagc 29640 acaagtagat gtagttaact ttaatctcac atagcaatct ttaatcagtg tgtaacatta 29700 gggaggactt gaaagagcca ccacattttc accgaggcca cgcggagtac gatcgagtgt 29760 acagtgaaca atgctaggga gagctgccta tatggaagag ccctaatgtg taaaattaat 29820 tttagtagtg ctatccccat gtgattttaa tagcttctta ggagaatgac aaaaaaaaaa 29880 aaaaaaaaaa aaaaaaaaaa aaa 29903 <210> 2 <211> 7096 <212> PRT <213> SARS-CoV2 <400> 2 Met Glu Ser Leu Val Pro Gly Phe Asn Glu Lys Thr Hes Val Gln Leu 1 5 10 15 Ser Leu Pro Val Leu Gln Val Arg Asp Val Leu Val Arg Gly Phe Gly 20 25 30 Asp Ser Val Glu Glu Val Leu Ser Glu Ala Arg Gln Hes Leu Lys Asp 35 40 45 Gly Thr Cys Gly Leu Val Glu Val Glu Lys Gly Val Leu Pro Gln Leu 50 55 60 Glu Gln Pro Tyr Val Phe Ile Lys Arg Ser Asp Ala Arg Thr Ala Pro 65 70 75 80 Hes Gly Hes Val Met Val Glu Leu Val Ala Glu Leu Glu Gly Ile Gln 85 90 95 Tyr Gly Arg Ser Gly Glu Thr Leu Gly Val Leu Val Pro Hes Val Gly 100 105 110 Glu Ile Pro Val Ala Tyr Arg Lys Val Leu Leu Arg Lys Asn Gly Asn 115 120 125 Lys Gly Ala Gly Gly Hes Ser Tyr Gly Ala Asp Leu Lys Ser Phe Asp 130 135 140 Leu Gly Asp Glu Leu Gly Thr Asp Pro Tyr Glu Asp Phe Gln Glu Asn 145 150 155 160 Trp Asn Thr Lys Hes Ser Ser Gly Val Thr Arg Glu Leu Met Arg Glu 165 170 175 Leu Asn Gly Gly Ala Tyr Thr Arg Tyr Val Asp Asn Asn Phe Cys Gly 180 185 190 Pro Asp Gly Tyr Pro Leu Glu Cys Ile Lys Asp Leu Leu Ala Arg Ala 195 200 205 Gly Lys Ala Ser Cys Thr Leu Ser Glu Gln Leu Asp Phe Ile Asp Thr 210 215 220 Lys Arg Gly Val Tyr Cys Cys Arg Glu Hes Glu Hes Glu Ile Ala Trp 225 230 235 240 Tyr Thr Glu Arg Ser Glu Lys Ser Tyr Glu Leu Gln Thr Pro Phe Glu 245 250 255 Ile Lys Leu Ala Lys Lys Phe Asp Thr Phe Asn Gly Glu Cys Pro Asn 260 265 270 Phe Val Phe Pro Leu Asn Ser Ile Ile Lys Thr Ile Gln Pro Arg Val 275 280 285 Glu Lys Lys Lys Leu Asp Gly Phe Met Gly Arg Ile Arg Ser Val Tyr 290 295 300 Pro Val Ala Ser Pro Asn Glu Cys Asn Gln Met Cys Leu Ser Thr Leu 305 310 315 320 Met Lys Cys Asp Hes Cys Gly Glu Thr Ser Trp Gln Thr Gly Asp Phe 325 330 335 Val Lys Ala Thr Cys Glu Phe Cys Gly Thr Glu Asn Leu Thr Lys Glu 340 345 350 Gly Ala Thr Thr Cys Gly Tyr Leu Pro Gln Asn Ala Val Val Lys Ile 355 360 365 Tyr Cys Pro Ala Cys Hes Asn Ser Glu Val Gly Pro Glu Hes Ser Leu 370 375 380 Ala Glu Tyr Hes Asn Glu Ser Gly Leu Lys Thr Ile Leu Arg Lys Gly 385 390 395 400 Gly Arg Thr Ile Ala Phe Gly Gly Cys Val Phe Ser Tyr Val Gly Cys 405 410 415 Hes Asn Lys Cys Ala Tyr Trp Val Pro Arg Ala Ser Ala Asn Ile Gly 420 425 430 Cys Asn Hes Thr Gly Val Val Gly Glu Gly Ser Glu Gly Leu Asn Asp 435 440 445 Asn Leu Leu Glu Ile Leu Gln Lys Glu Lys Val Asn Ile Asn Ile Val 450 455 460 Gly Asp Phe Lys Leu Asn Glu Glu Ile Ala Ile Ile Leu Ala Ser Phe 465 470 475 480 Ser Ala Ser Thr Ser Ala Phe Val Glu Thr Val Lys Gly Leu Asp Tyr 485 490 495 Lys Ala Phe Lys Gln Ile Val Glu Ser Cys Gly Asn Phe Lys Val Thr 500 505 510 Lys Gly Lys Ala Lys Lys Gly Ala Trp Asn Ile Gly Glu Gln Lys Ser 515 520 525 Ile Leu Ser Pro Leu Tyr Ala Phe Ala Ser Glu Ala Ala Arg Val Val 530 535 540 Arg Ser Ile Phe Ser Arg Thr Leu Glu Thr Ala Gln Asn Ser Val Arg 545 550 555 560 Val Leu Gln Lys Ala Ala Ile Thr Ile Leu Asp Gly Ile Ser Gln Tyr 565 570 575 Ser Leu Arg Leu Ile Asp Ala Met Met Phe Thr Ser Asp Leu Ala Thr 580 585 590 Asn Asn Leu Val Val Met Ala Tyr Ile Thr Gly Gly Val Val Gln Leu 595 600 605 Thr Ser Gln Trp Leu Thr Asn Ile Phe Gly Thr Val Tyr Glu Lys Leu 610 615 620 Lys Pro Val Leu Asp Trp Leu Glu Glu Lys Phe Lys Glu Gly Val Glu 625 630 635 640 Phe Leu Arg Asp Gly Trp Glu Ile Val Lys Phe Ile Ser Thr Cys Ala 645 650 655 Cys Glu Ile Val Gly Gly Gln Ile Val Thr Cys Ala Lys Glu Ile Lys 660 665 670 Glu Ser Val Gln Thr Phe Phe Lys Leu Val Asn Lys Phe Leu Ala Leu 675 680 685 Cys Ala Asp Ser Ile Ile Ile Gly Gly Ala Lys Leu Lys Ala Leu Asn 690 695 700 Leu Gly Glu Thr Phe Val Thr Hes Ser Lys Gly Leu Tyr Arg Lys Cys 705 710 715 720 Val Lys Ser Arg Glu Glu Thr Gly Leu Leu Met Pro Leu Lys Ala Pro 725 730 735 Lys Glu Ile Ile Phe Leu Glu Gly Glu Thr Leu Pro Thr Glu Val Leu 740 745 750 Thr Glu Glu Val Val Leu Lys Thr Gly Asp Leu Gln Pro Leu Glu Gln 755 760 765 Pro Thr Ser Glu Ala Val Glu Ala Pro Leu Val Gly Thr Pro Val Cys 770 775 780 Ile Asn Gly Leu Met Leu Leu Glu Ile Lys Asp Thr Glu Lys Tyr Cys 785 790 795 800 Ala Leu Ala Pro Asn Met Met Val Thr Asn Asn Thr Phe Thr Leu Lys 805 810 815 Gly Gly Ala Pro Thr Lys Val Thr Phe Gly Asp Asp Thr Val Ile Glu 820 825 830 Val Gln Gly Tyr Lys Ser Val Asn Ile Thr Phe Glu Leu Asp Glu Arg 835 840 845 Ile Asp Lys Val Leu Asn Glu Lys Cys Ser Ala Tyr Thr Val Glu Leu 850 855 860 Gly Thr Glu Val Asn Glu Phe Ala Cys Val Val Ala Asp Ala Val Ile 865 870 875 880 Lys Thr Leu Gln Pro Val Ser Glu Leu Leu Thr Pro Leu Gly Ile Asp 885 890 895 Leu Asp Glu Trp Ser Met Ala Thr Tyr Tyr Leu Phe Asp Glu Ser Gly 900 905 910 Glu Phe Lys Leu Ala Ser Hes Met Tyr Cys Ser Phe Tyr Pro Pro Asp 915 920 925 Glu Asp Glu Glu Glu Gly Asp Cys Glu Glu Glu Glu Phe Glu Pro Ser 930 935 940 Thr Gln Tyr Glu Tyr Gly Thr Glu Asp Asp Tyr Gln Gly Lys Pro Leu 945 950 955 960 Glu Phe Gly Ala Thr Ser Ala Ala Leu Gln Pro Glu Glu Glu Gln Glu 965 970 975 Glu Asp Trp Leu Asp Asp Asp Ser Gln Gln Thr Val Gly Gln Gln Asp 980 985 990 Gly Ser Glu Asp Asn Gln Thr Thr Thr Ile Gln Thr Ile Val Glu Val 995 1000 1005 Gln Pro Gln Leu Glu Met Glu Leu Thr Pro Val Val Gln Thr Ile 1010 1015 1020 Glu Val Asn Ser Phe Ser Gly Tyr Leu Lys Leu Thr Asp Asn Val 1025 1030 1035 Tyr Ile Lys Asn Ala Asp Ile Val Glu Glu Ala Lys Lys Val Lys 1040 1045 1050 Pro Thr Val Val Val Asn Ala Ala Asn Val Tyr Leu Lys Hes Gly 1055 1060 1065 Gly Gly Val Ala Gly Ala Leu Asn Lys Ala Thr Asn Asn Ala Met 1070 1075 1080 Gln Val Glu Ser Asp Asp Tyr Ile Ala Thr Asn Gly Pro Leu Lys 1085 1090 1095 Val Gly Gly Ser Cys Val Leu Ser Gly Hes Asn Leu Ala Lys Hes 1100 1105 1110 Cys Leu Hes Val Val Gly Pro Asn Val Asn Lys Gly Glu Asp Ile 1115 1120 1125 Gln Leu Leu Lys Ser Ala Tyr Glu Asn Phe Asn Gln Hes Glu Val 1130 1135 1140 Leu Leu Ala Pro Leu Leu Ser Ala Gly Ile Phe Gly Ala Asp Pro 1145 1150 1155 Ile Hes Ser Leu Arg Val Cys Val Asp Thr Val Arg Thr Asn Val 1160 1165 1170 Tyr Leu Ala Val Phe Asp Lys Asn Leu Tyr Asp Lys Leu Val Ser 1175 1180 1185 Ser Phe Leu Glu Met Lys Ser Glu Lys Gln Val Glu Gln Lys Ile 1190 1195 1200 Ala Glu Ile Pro Lys Glu Glu Val Lys Pro Phe Ile Thr Glu Ser 1205 1210 1215 Lys Pro Ser Val Glu Gln Arg Lys Gln Asp Asp Lys Lys Ile Lys 1220 1225 1230 Ala Cys Val Glu Glu Val Thr Thr Thr Leu Glu Glu Thr Lys Phe 1235 1240 1245 Leu Thr Glu Asn Leu Leu Leu Tyr Ile Asp Ile Asn Gly Asn Leu 1250 1255 1260 Hes Pro Asp Ser Ala Thr Leu Val Ser Asp Ile Asp Ile Thr Phe 1265 1270 1275 Leu Lys Lys Asp Ala Pro Tyr Ile Val Gly Asp Val Val Gln Glu 1280 1285 1290 Gly Val Leu Thr Ala Val Val Ile Pro Thr Lys Lys Ala Gly Gly 1295 1300 1305 Thr Thr Glu Met Leu Ala Lys Ala Leu Arg Lys Val Pro Thr Asp 1310 1315 1320 Asn Tyr Ile Thr Thr Tyr Pro Gly Gln Gly Leu Asn Gly Tyr Thr 1325 1330 1335 Val Glu Glu Ala Lys Thr Val Leu Lys Lys Cys Lys Ser Ala Phe 1340 1345 1350 Tyr Ile Leu Pro Ser Ile Ile Ser Asn Glu Lys Gln Glu Ile Leu 1355 1360 1365 Gly Thr Val Ser Trp Asn Leu Arg Glu Met Leu Ala Hes Ala Glu 1370 1375 1380 Glu Thr Arg Lys Leu Met Pro Val Cys Val Glu Thr Lys Ala Ile 1385 1390 1395 Val Ser Thr Ile Gln Arg Lys Tyr Lys Gly Ile Lys Ile Gln Glu 1400 1405 1410 Gly Val Val Asp Tyr Gly Ala Arg Phe Tyr Phe Tyr Thr Ser Lys 1415 1420 1425 Thr Thr Val Ala Ser Leu Ile Asn Thr Leu Asn Asp Leu Asn Glu 1430 1435 1440 Thr Leu Val Thr Met Pro Leu Gly Tyr Val Thr Hes Gly Leu Asn 1445 1450 1455 Leu Glu Glu Ala Ala Arg Tyr Met Arg Ser Leu Lys Val Pro Ala 1460 1465 1470 Thr Val Ser Val Ser Ser Pro Asp Ala Val Thr Ala Tyr Asn Gly 1475 1480 1485 Tyr Leu Thr Ser Ser Ser Lys Thr Pro Glu Glu Hes Phe Ile Glu 1490 1495 1500 Thr Ile Ser Leu Ala Gly Ser Tyr Lys Asp Trp Ser Tyr Ser Gly 1505 1510 1515 Gln Ser Thr Gln Leu Gly Ile Glu Phe Leu Lys Arg Gly Asp Lys 1520 1525 1530 Ser Val Tyr Tyr Thr Ser Asn Pro Thr Thr Phe Hes Leu Asp Gly 1535 1540 1545 Glu Val Ile Thr Phe Asp Asn Leu Lys Thr Leu Leu Ser Leu Arg 1550 1555 1560 Glu Val Arg Thr Ile Lys Val Phe Thr Thr Val Asp Asn Ile Asn 1565 1570 1575 Leu Hes Thr Gln Val Val Asp Met Ser Met Thr Tyr Gly Gln Gln 1580 1585 1590 Phe Gly Pro Thr Tyr Leu Asp Gly Ala Asp Val Thr Lys Ile Lys 1595 1600 1605 Pro Hes Asn Ser Hes Glu Gly Lys Thr Phe Tyr Val Leu Pro Asn 1610 1615 1620 Asp Asp Thr Leu Arg Val Glu Ala Phe Glu Tyr Tyr Hes Thr Thr 1625 1630 1635 Asp Pro Ser Phe Leu Gly Arg Tyr Met Ser Ala Leu Asn Hes Thr 1640 1645 1650 Lys Lys Trp Lys Tyr Pro Gln Val Asn Gly Leu Thr Ser Ile Lys 1655 1660 1665 Trp Ala Asp Asn Asn Cys Tyr Leu Ala Thr Ala Leu Leu Thr Leu 1670 1675 1680 Gln Gln Ile Glu Leu Lys Phe Asn Pro Pro Ala Leu Gln Asp Ala 1685 1690 1695 Tyr Tyr Arg Ala Arg Ala Gly Glu Ala Ala Asn Phe Cys Ala Leu 1700 1705 1710 Ile Leu Ala Tyr Cys Asn Lys Thr Val Gly Glu Leu Gly Asp Val 1715 1720 1725 Arg Glu Thr Met Ser Tyr Leu Phe Gln Hes Ala Asn Leu Asp Ser 1730 1735 1740 Cys Lys Arg Val Leu Asn Val Val Cys Lys Thr Cys Gly Gln Gln 1745 1750 1755 Gln Thr Thr Leu Lys Gly Val Glu Ala Val Met Tyr Met Gly Thr 1760 1765 1770 Leu Ser Tyr Glu Gln Phe Lys Lys Gly Val Gln Ile Pro Cys Thr 1775 1780 1785 Cys Gly Lys Gln Ala Thr Lys Tyr Leu Val Gln Gln Glu Ser Pro 1790 1795 1800 Phe Val Met Met Ser Ala Pro Pro Ala Gln Tyr Glu Leu Lys Hes 1805 1810 1815 Gly Thr Phe Thr Cys Ala Ser Glu Tyr Thr Gly Asn Tyr Gln Cys 1820 1825 1830 Gly Hes Tyr Lys Hes Ile Thr Ser Lys Glu Thr Leu Tyr Cys Ile 1835 1840 1845 Asp Gly Ala Leu Leu Thr Lys Ser Ser Glu Tyr Lys Gly Pro Ile 1850 1855 1860 Thr Asp Val Phe Tyr Lys Glu Asn Ser Tyr Thr Thr Thr Ile Lys 1865 1870 1875 Pro Val Thr Tyr Lys Leu Asp Gly Val Val Cys Thr Glu Ile Asp 1880 1885 1890 Pro Lys Leu Asp Asn Tyr Tyr Lys Lys Asp Asn Ser Tyr Phe Thr 1895 1900 1905 Glu Gln Pro Ile Asp Leu Val Pro Asn Gln Pro Tyr Pro Asn Ala 1910 1915 1920 Ser Phe Asp Asn Phe Lys Phe Val Cys Asp Asn Ile Lys Phe Ala 1925 1930 1935 Asp Asp Leu Asn Gln Leu Thr Gly Tyr Lys Lys Pro Ala Ser Arg 1940 1945 1950 Glu Leu Lys Val Thr Phe Phe Pro Asp Leu Asn Gly Asp Val Val 1955 1960 1965 Ala Ile Asp Tyr Lys Hes Tyr Thr Pro Ser Phe Lys Lys Gly Ala 1970 1975 1980 Lys Leu Leu Hes Lys Pro Ile Val Trp Hes Val Asn Asn Ala Thr 1985 1990 1995 Asn Lys Ala Thr Tyr Lys Pro Asn Thr Trp Cys Ile Arg Cys Leu 2000 2005 2010 Trp Ser Thr Lys Pro Val Glu Thr Ser Asn Ser Phe Asp Val Leu 2015 2020 2025 Lys Ser Glu Asp Ala Gln Gly Met Asp Asn Leu Ala Cys Glu Asp 2030 2035 2040 Leu Lys Pro Val Ser Glu Glu Val Val Glu Asn Pro Thr Ile Gln 2045 2050 2055 Lys Asp Val Leu Glu Cys Asn Val Lys Thr Thr Glu Val Val Gly 2060 2065 2070 Asp Ile Ile Leu Lys Pro Ala Asn Asn Ser Leu Lys Ile Thr Glu 2075 2080 2085 Glu Val Gly Hes Thr Asp Leu Met Ala Ala Tyr Val Asp Asn Ser 2090 2095 2100 Ser Leu Thr Ile Lys Lys Pro Asn Glu Leu Ser Arg Val Leu Gly 2105 2110 2115 Leu Lys Thr Leu Ala Thr Hes Gly Leu Ala Ala Val Asn Ser Val 2120 2125 2130 Pro Trp Asp Thr Ile Ala Asn Tyr Ala Lys Pro Phe Leu Asn Lys 2135 2140 2145 Val Val Ser Thr Thr Thr Asn Ile Val Thr Arg Cys Leu Asn Arg 2150 2155 2160 Val Cys Thr Asn Tyr Met Pro Tyr Phe Phe Thr Leu Leu Leu Gln 2165 2170 2175 Leu Cys Thr Phe Thr Arg Ser Thr Asn Ser Arg Ile Lys Ala Ser 2180 2185 2190 Met Pro Thr Thr Ile Ala Lys Asn Thr Val Lys Ser Val Gly Lys 2195 2200 2205 Phe Cys Leu Glu Ala Ser Phe Asn Tyr Leu Lys Ser Pro Asn Phe 2210 2215 2220 Ser Lys Leu Ile Asn Ile Ile Ile Trp Phe Leu Leu Leu Ser Val 2225 2230 2235 Cys Leu Gly Ser Leu Ile Tyr Ser Thr Ala Ala Leu Gly Val Leu 2240 2245 2250 Met Ser Asn Leu Gly Met Pro Ser Tyr Cys Thr Gly Tyr Arg Glu 2255 2260 2265 Gly Tyr Leu Asn Ser Thr Asn Val Thr Ile Ala Thr Tyr Cys Thr 2270 2275 2280 Gly Ser Ile Pro Cys Ser Val Cys Leu Ser Gly Leu Asp Ser Leu 2285 2290 2295 Asp Thr Tyr Pro Ser Leu Glu Thr Ile Gln Ile Thr Ile Ser Ser 2300 2305 2310 Phe Lys Trp Asp Leu Thr Ala Phe Gly Leu Val Ala Glu Trp Phe 2315 2320 2325 Leu Ala Tyr Ile Leu Phe Thr Arg Phe Phe Tyr Val Leu Gly Leu 2330 2335 2340 Ala Ala Ile Met Gln Leu Phe Phe Ser Tyr Phe Ala Val Hes Phe 2345 2350 2355 Ile Ser Asn Ser Trp Leu Met Trp Leu Ile Ile Asn Leu Val Gln 2360 2365 2370 Met Ala Pro Ile Ser Ala Met Val Arg Met Tyr Ile Phe Phe Ala 2375 2380 2385 Ser Phe Tyr Tyr Val Trp Lys Ser Tyr Val Hes Val Val Asp Gly 2390 2395 2400 Cys Asn Ser Ser Thr Cys Met Met Cys Tyr Lys Arg Asn Arg Ala 2405 2410 2415 Thr Arg Val Glu Cys Thr Thr Ile Val Asn Gly Val Arg Arg Ser 2420 2425 2430 Phe Tyr Val Tyr Ala Asn Gly Gly Lys Gly Phe Cys Lys Leu Hes 2435 2440 2445 Asn Trp Asn Cys Val Asn Cys Asp Thr Phe Cys Ala Gly Ser Thr 2450 2455 2460 Phe Ile Ser Asp Glu Val Ala Arg Asp Leu Ser Leu Gln Phe Lys 2465 2470 2475 Arg Pro Ile Asn Pro Thr Asp Gln Ser Ser Tyr Ile Val Asp Ser 2480 2485 2490 Val Thr Val Lys Asn Gly Ser Ile Hes Leu Tyr Phe Asp Lys Ala 2495 2500 2505 Gly Gln Lys Thr Tyr Glu Arg Hes Ser Leu Ser Hes Phe Val Asn 2510 2515 2520 Leu Asp Asn Leu Arg Ala Asn Asn Thr Lys Gly Ser Leu Pro Ile 2525 2530 2535 Asn Val Ile Val Phe Asp Gly Lys Ser Lys Cys Glu Glu Ser Ser 2540 2545 2550 Ala Lys Ser Ala Ser Val Tyr Tyr Ser Gln Leu Met Cys Gln Pro 2555 2560 2565 Ile Leu Leu Leu Asp Gln Ala Leu Val Ser Asp Val Gly Asp Ser 2570 2575 2580 Ala Glu Val Ala Val Lys Met Phe Asp Ala Tyr Val Asn Thr Phe 2585 2590 2595 Ser Ser Thr Phe Asn Val Pro Met Glu Lys Leu Lys Thr Leu Val 2600 2605 2610 Ala Thr Ala Glu Ala Glu Leu Ala Lys Asn Val Ser Leu Asp Asn 2615 2620 2625 Val Leu Ser Thr Phe Ile Ser Ala Ala Arg Gln Gly Phe Val Asp 2630 2635 2640 Ser Asp Val Glu Thr Lys Asp Val Val Glu Cys Leu Lys Leu Ser 2645 2650 2655 Hes Gln Ser Asp Ile Glu Val Thr Gly Asp Ser Cys Asn Asn Tyr 2660 2665 2670 Met Leu Thr Tyr Asn Lys Val Glu Asn Met Thr Pro Arg Asp Leu 2675 2680 2685 Gly Ala Cys Ile Asp Cys Ser Ala Arg Hes Ile Asn Ala Gln Val 2690 2695 2700 Ala Lys Ser Hes Asn Ile Ala Leu Ile Trp Asn Val Lys Asp Phe 2705 2710 2715 Met Ser Leu Ser Glu Gln Leu Arg Lys Gln Ile Arg Ser Ala Ala 2720 2725 2730 Lys Lys Asn Asn Leu Pro Phe Lys Leu Thr Cys Ala Thr Thr Arg 2735 2740 2745 Gln Val Val Asn Val Val Thr Thr Lys Ile Ala Leu Lys Gly Gly 2750 2755 2760 Lys Ile Val Asn Asn Trp Leu Lys Gln Leu Ile Lys Val Thr Leu 2765 2770 2775 Val Phe Leu Phe Val Ala Ala Ile Phe Tyr Leu Ile Thr Pro Val 2780 2785 2790 Hes Val Met Ser Lys Hes Thr Asp Phe Ser Ser Glu Ile Ile Gly 2795 2800 2805 Tyr Lys Ala Ile Asp Gly Gly Val Thr Arg Asp Ile Ala Ser Thr 2810 2815 2820 Asp Thr Cys Phe Ala Asn Lys Hes Ala Asp Phe Asp Thr Trp Phe 2825 2830 2835 Ser Gln Arg Gly Gly Ser Tyr Thr Asn Asp Lys Ala Cys Pro Leu 2840 2845 2850 Ile Ala Ala Val Ile Thr Arg Glu Val Gly Phe Val Val Pro Gly 2855 2860 2865 Leu Pro Gly Thr Ile Leu Arg Thr Thr Asn Gly Asp Phe Leu Hes 2870 2875 2880 Phe Leu Pro Arg Val Phe Ser Ala Val Gly Asn Ile Cys Tyr Thr 2885 2890 2895 Pro Ser Lys Leu Ile Glu Tyr Thr Asp Phe Ala Thr Ser Ala Cys 2900 2905 2910 Val Leu Ala Ala Glu Cys Thr Ile Phe Lys Asp Ala Ser Gly Lys 2915 2920 2925 Pro Val Pro Tyr Cys Tyr Asp Thr Asn Val Leu Glu Gly Ser Val 2930 2935 2940 Ala Tyr Glu Ser Leu Arg Pro Asp Thr Arg Tyr Val Leu Met Asp 2945 2950 2955 Gly Ser Ile Ile Gln Phe Pro Asn Thr Tyr Leu Glu Gly Ser Val 2960 2965 2970 Arg Val Val Thr Thr Phe Asp Ser Glu Tyr Cys Arg Hes Gly Thr 2975 2980 2985 Cys Glu Arg Ser Glu Ala Gly Val Cys Val Ser Thr Ser Gly Arg 2990 2995 3000 Trp Val Leu Asn Asn Asp Tyr Tyr Arg Ser Leu Pro Gly Val Phe 3005 3010 3015 Cys Gly Val Asp Ala Val Asn Leu Leu Thr Asn Met Phe Thr Pro 3020 3025 3030 Leu Ile Gln Pro Ile Gly Ala Leu Asp Ile Ser Ala Ser Ile Val 3035 3040 3045 Ala Gly Gly Ile Val Ala Ile Val Val Thr Cys Leu Ala Tyr Tyr 3050 3055 3060 Phe Met Arg Phe Arg Arg Ala Phe Gly Glu Tyr Ser Hes Val Val 3065 3070 3075 Ala Phe Asn Thr Leu Leu Phe Leu Met Ser Phe Thr Val Leu Cys 3080 3085 3090 Leu Thr Pro Val Tyr Ser Phe Leu Pro Gly Val Tyr Ser Val Ile 3095 3100 3105 Tyr Leu Tyr Leu Thr Phe Tyr Leu Thr Asn Asp Val Ser Phe Leu 3110 3115 3120 Ala Hes Ile Gln Trp Met Val Met Phe Thr Pro Leu Val Pro Phe 3125 3130 3135 Trp Ile Thr Ile Ala Tyr Ile Ile Cys Ile Ser Thr Lys Hes Phe 3140 3145 3150 Tyr Trp Phe Phe Ser Asn Tyr Leu Lys Arg Arg Val Val Phe Asn 3155 3160 3165 Gly Val Ser Phe Ser Thr Phe Glu Glu Ala Ala Leu Cys Thr Phe 3170 3175 3180 Leu Leu Asn Lys Glu Met Tyr Leu Lys Leu Arg Ser Asp Val Leu 3185 3190 3195 Leu Pro Leu Thr Gln Tyr Asn Arg Tyr Leu Ala Leu Tyr Asn Lys 3200 3205 3210 Tyr Lys Tyr Phe Ser Gly Ala Met Asp Thr Thr Ser Tyr Arg Glu 3215 3220 3225 Ala Ala Cys Cys Hes Leu Ala Lys Ala Leu Asn Asp Phe Ser Asn 3230 3235 3240 Ser Gly Ser Asp Val Leu Tyr Gln Pro Pro Gln Thr Ser Ile Thr 3245 3250 3255 Ser Ala Val Leu Gln Ser Gly Phe Arg Lys Met Ala Phe Pro Ser 3260 3265 3270 Gly Lys Val Glu Gly Cys Met Val Gln Val Thr Cys Gly Thr Thr 3275 3280 3285 Thr Leu Asn Gly Leu Trp Leu Asp Asp Val Val Tyr Cys Pro Arg 3290 3295 3300 Hes Val Ile Cys Thr Ser Glu Asp Met Leu Asn Pro Asn Tyr Glu 3305 3310 3315 Asp Leu Leu Ile Arg Lys Ser Asn Hes Asn Phe Leu Val Gln Ala 3320 3325 3330 Gly Asn Val Gln Leu Arg Val Ile Gly Hes Ser Met Gln Asn Cys 3335 3340 3345 Val Leu Lys Leu Lys Val Asp Thr Ala Asn Pro Lys Thr Pro Lys 3350 3355 3360 Tyr Lys Phe Val Arg Ile Gln Pro Gly Gln Thr Phe Ser Val Leu 3365 3370 3375 Ala Cys Tyr Asn Gly Ser Pro Ser Gly Val Tyr Gln Cys Ala Met 3380 3385 3390 Arg Pro Asn Phe Thr Ile Lys Gly Ser Phe Leu Asn Gly Ser Cys 3395 3400 3405 Gly Ser Val Gly Phe Asn Ile Asp Tyr Asp Cys Val Ser Phe Cys 3410 3415 3420 Tyr Met Hes Hes Met Glu Leu Pro Thr Gly Val Hes Ala Gly Thr 3425 3430 3435 Asp Leu Glu Gly Asn Phe Tyr Gly Pro Phe Val Asp Arg Gln Thr 3440 3445 3450 Ala Gln Ala Ala Gly Thr Asp Thr Thr Ile Thr Val Asn Val Leu 3455 3460 3465 Ala Trp Leu Tyr Ala Ala Val Ile Asn Gly Asp Arg Trp Phe Leu 3470 3475 3480 Asn Arg Phe Thr Thr Thr Leu Asn Asp Phe Asn Leu Val Ala Met 3485 3490 3495 Lys Tyr Asn Tyr Glu Pro Leu Thr Gln Asp Hes Val Asp Ile Leu 3500 3505 3510 Gly Pro Leu Ser Ala Gln Thr Gly Ile Ala Val Leu Asp Met Cys 3515 3520 3525 Ala Ser Leu Lys Glu Leu Leu Gln Asn Gly Met Asn Gly Arg Thr 3530 3535 3540 Ile Leu Gly Ser Ala Leu Leu Glu Asp Glu Phe Thr Pro Phe Asp 3545 3550 3555 Val Val Arg Gln Cys Ser Gly Val Thr Phe Gln Ser Ala Val Lys 3560 3565 3570 Arg Thr Ile Lys Gly Thr Hes Hes Trp Leu Leu Leu Thr Ile Leu 3575 3580 3585 Thr Ser Leu Leu Val Leu Val Gln Ser Thr Gln Trp Ser Leu Phe 3590 3595 3600 Phe Phe Leu Tyr Glu Asn Ala Phe Leu Pro Phe Ala Met Gly Ile 3605 3610 3615 Ile Ala Met Ser Ala Phe Ala Met Met Phe Val Lys Hes Lys Hes 3620 3625 3630 Ala Phe Leu Cys Leu Phe Leu Leu Pro Ser Leu Ala Thr Val Ala 3635 3640 3645 Tyr Phe Asn Met Val Tyr Met Pro Ala Ser Trp Val Met Arg Ile 3650 3655 3660 Met Thr Trp Leu Asp Met Val Asp Thr Ser Leu Ser Gly Phe Lys 3665 3670 3675 Leu Lys Asp Cys Val Met Tyr Ala Ser Ala Val Val Leu Leu Ile 3680 3685 3690 Leu Met Thr Ala Arg Thr Val Tyr Asp Asp Gly Ala Arg Arg Val 3695 3700 3705 Trp Thr Leu Met Asn Val Leu Thr Leu Val Tyr Lys Val Tyr Tyr 3710 3715 3720 Gly Asn Ala Leu Asp Gln Ala Ile Ser Met Trp Ala Leu Ile Ile 3725 3730 3735 Ser Val Thr Ser Asn Tyr Ser Gly Val Val Thr Thr Val Met Phe 3740 3745 3750 Leu Ala Arg Gly Ile Val Phe Met Cys Val Glu Tyr Cys Pro Ile 3755 3760 3765 Phe Phe Ile Thr Gly Asn Thr Leu Gln Cys Ile Met Leu Val Tyr 3770 3775 3780 Cys Phe Leu Gly Tyr Phe Cys Thr Cys Tyr Phe Gly Leu Phe Cys 3785 3790 3795 Leu Leu Asn Arg Tyr Phe Arg Leu Thr Leu Gly Val Tyr Asp Tyr 3800 3805 3810 Leu Val Ser Thr Gln Glu Phe Arg Tyr Met Asn Ser Gln Gly Leu 3815 3820 3825 Leu Pro Pro Lys Asn Ser Ile Asp Ala Phe Lys Leu Asn Ile Lys 3830 3835 3840 Leu Leu Gly Val Gly Gly Lys Pro Cys Ile Lys Val Ala Thr Val 3845 3850 3855 Gln Ser Lys Met Ser Asp Val Lys Cys Thr Ser Val Val Leu Leu 3860 3865 3870 Ser Val Leu Gln Gln Leu Arg Val Glu Ser Ser Ser Lys Leu Trp 3875 3880 3885 Ala Gln Cys Val Gln Leu Hes Asn Asp Ile Leu Leu Ala Lys Asp 3890 3895 3900 Thr Thr Glu Ala Phe Glu Lys Met Val Ser Leu Leu Ser Val Leu 3905 3910 3915 Leu Ser Met Gln Gly Ala Val Asp Ile Asn Lys Leu Cys Glu Glu 3920 3925 3930 Met Leu Asp Asn Arg Ala Thr Leu Gln Ala Ile Ala Ser Glu Phe 3935 3940 3945 Ser Ser Leu Pro Ser Tyr Ala Ala Phe Ala Thr Ala Gln Glu Ala 3950 3955 3960 Tyr Glu Gln Ala Val Ala Asn Gly Asp Ser Glu Val Val Leu Lys 3965 3970 3975 Lys Leu Lys Lys Ser Leu Asn Val Ala Lys Ser Glu Phe Asp Arg 3980 3985 3990 Asp Ala Ala Met Gln Arg Lys Leu Glu Lys Met Ala Asp Gln Ala 3995 4000 4005 Met Thr Gln Met Tyr Lys Gln Ala Arg Ser Glu Asp Lys Arg Ala 4010 4015 4020 Lys Val Thr Ser Ala Met Gln Thr Met Leu Phe Thr Met Leu Arg 4025 4030 4035 Lys Leu Asp Asn Asp Ala Leu Asn Asn Ile Ile Asn Asn Ala Arg 4040 4045 4050 Asp Gly Cys Val Pro Leu Asn Ile Ile Pro Leu Thr Thr Ala Ala 4055 4060 4065 Lys Leu Met Val Val Ile Pro Asp Tyr Asn Thr Tyr Lys Asn Thr 4070 4075 4080 Cys Asp Gly Thr Thr Phe Thr Tyr Ala Ser Ala Leu Trp Glu Ile 4085 4090 4095 Gln Gln Val Val Asp Ala Asp Ser Lys Ile Val Gln Leu Ser Glu 4100 4105 4110 Ile Ser Met Asp Asn Ser Pro Asn Leu Ala Trp Pro Leu Ile Val 4115 4120 4125 Thr Ala Leu Arg Ala Asn Ser Ala Val Lys Leu Gln Asn Asn Glu 4130 4135 4140 Leu Ser Pro Val Ala Leu Arg Gln Met Ser Cys Ala Ala Gly Thr 4145 4150 4155 Thr Gln Thr Ala Cys Thr Asp Asp Asn Ala Leu Ala Tyr Tyr Asn 4160 4165 4170 Thr Thr Lys Gly Gly Arg Phe Val Leu Ala Leu Leu Ser Asp Leu 4175 4180 4185 Gln Asp Leu Lys Trp Ala Arg Phe Pro Lys Ser Asp Gly Thr Gly 4190 4195 4200 Thr Ile Tyr Thr Glu Leu Glu Pro Pro Cys Arg Phe Val Thr Asp 4205 4210 4215 Thr Pro Lys Gly Pro Lys Val Lys Tyr Leu Tyr Phe Ile Lys Gly 4220 4225 4230 Leu Asn Asn Leu Asn Arg Gly Met Val Leu Gly Ser Leu Ala Ala 4235 4240 4245 Thr Val Arg Leu Gln Ala Gly Asn Ala Thr Glu Val Pro Ala Asn 4250 4255 4260 Ser Thr Val Leu Ser Phe Cys Ala Phe Ala Val Asp Ala Ala Lys 4265 4270 4275 Ala Tyr Lys Asp Tyr Leu Ala Ser Gly Gly Gln Pro Ile Thr Asn 4280 4285 4290 Cys Val Lys Met Leu Cys Thr Hes Thr Gly Thr Gly Gln Ala Ile 4295 4300 4305 Thr Val Thr Pro Glu Ala Asn Met Asp Gln Glu Ser Phe Gly Gly 4310 4315 4320 Ala Ser Cys Cys Leu Tyr Cys Arg Cys Hes Ile Asp Hes Pro Asn 4325 4330 4335 Pro Lys Gly Phe Cys Asp Leu Lys Gly Lys Tyr Val Gln Ile Pro 4340 4345 4350 Thr Thr Cys Ala Asn Asp Pro Val Gly Phe Thr Leu Lys Asn Thr 4355 4360 4365 Val Cys Thr Val Cys Gly Met Trp Lys Gly Tyr Gly Cys Ser Cys 4370 4375 4380 Asp Gln Leu Arg Glu Pro Met Leu Gln Ser Ala Asp Ala Gln Ser 4385 4390 4395 Phe Leu Asn Arg Val Cys Gly Val Ser Ala Ala Arg Leu Thr Pro 4400 4405 4410 Cys Gly Thr Gly Thr Ser Thr Asp Val Val Tyr Arg Ala Phe Asp 4415 4420 4425 Ile Tyr Asn Asp Lys Val Ala Gly Phe Ala Lys Phe Leu Lys Thr 4430 4435 4440 Asn Cys Cys Arg Phe Gln Glu Lys Asp Glu Asp Asp Asn Leu Ile 4445 4450 4455 Asp Ser Tyr Phe Val Val Lys Arg Hes Thr Phe Ser Asn Tyr Gln 4460 4465 4470 Hes Glu Glu Thr Ile Tyr Asn Leu Leu Lys Asp Cys Pro Ala Val 4475 4480 4485 Ala Lys Hes Asp Phe Phe Lys Phe Arg Ile Asp Gly Asp Met Val 4490 4495 4500 Pro Hes Ile Ser Arg Gln Arg Leu Thr Lys Tyr Thr Met Ala Asp 4505 4510 4515 Leu Val Tyr Ala Leu Arg Hes Phe Asp Glu Gly Asn Cys Asp Thr 4520 4525 4530 Leu Lys Glu Ile Leu Val Thr Tyr Asn Cys Cys Asp Asp Asp Tyr 4535 4540 4545 Phe Asn Lys Lys Asp Trp Tyr Asp Phe Val Glu Asn Pro Asp Ile 4550 4555 4560 Leu Arg Val Tyr Ala Asn Leu Gly Glu Arg Val Arg Gln Ala Leu 4565 4570 4575 Leu Lys Thr Val Gln Phe Cys Asp Ala Met Arg Asn Ala Gly Ile 4580 4585 4590 Val Gly Val Leu Thr Leu Asp Asn Gln Asp Leu Asn Gly Asn Trp 4595 4600 4605 Tyr Asp Phe Gly Asp Phe Ile Gln Thr Thr Pro Gly Ser Gly Val 4610 4615 4620 Pro Val Val Asp Ser Tyr Tyr Ser Leu Leu Met Pro Ile Leu Thr 4625 4630 4635 Leu Thr Arg Ala Leu Thr Ala Glu Ser Hes Val Asp Thr Asp Leu 4640 4645 4650 Thr Lys Pro Tyr Ile Lys Trp Asp Leu Leu Lys Tyr Asp Phe Thr 4655 4660 4665 Glu Glu Arg Leu Lys Leu Phe Asp Arg Tyr Phe Lys Tyr Trp Asp 4670 4675 4680 Gln Thr Tyr Hes Pro Asn Cys Val Asn Cys Leu Asp Asp Arg Cys 4685 4690 4695 Ile Leu Hes Cys Ala Asn Phe Asn Val Leu Phe Ser Thr Val Phe 4700 4705 4710 Pro Pro Thr Ser Phe Gly Pro Leu Val Arg Lys Ile Phe Val Asp 4715 4720 4725 Gly Val Pro Phe Val Val Ser Thr Gly Tyr Hes Phe Arg Glu Leu 4730 4735 4740 Gly Val Val Hes Asn Gln Asp Val Asn Leu Hes Ser Ser Arg Leu 4745 4750 4755 Ser Phe Lys Glu Leu Leu Val Tyr Ala Ala Asp Pro Ala Met Hes 4760 4765 4770 Ala Ala Ser Gly Asn Leu Leu Leu Asp Lys Arg Thr Thr Cys Phe 4775 4780 4785 Ser Val Ala Ala Leu Thr Asn Asn Val Ala Phe Gln Thr Val Lys 4790 4795 4800 Pro Gly Asn Phe Asn Lys Asp Phe Tyr Asp Phe Ala Val Ser Lys 4805 4810 4815 Gly Phe Phe Lys Glu Gly Ser Ser Val Glu Leu Lys Hes Phe Phe 4820 4825 4830 Phe Ala Gln Asp Gly Asn Ala Ala Ile Ser Asp Tyr Asp Tyr Tyr 4835 4840 4845 Arg Tyr Asn Leu Pro Thr Met Cys Asp Ile Arg Gln Leu Leu Phe 4850 4855 4860 Val Val Glu Val Val Asp Lys Tyr Phe Asp Cys Tyr Asp Gly Gly 4865 4870 4875 Cys Ile Asn Ala Asn Gln Val Ile Val Asn Asn Leu Asp Lys Ser 4880 4885 4890 Ala Gly Phe Pro Phe Asn Lys Trp Gly Lys Ala Arg Leu Tyr Tyr 4895 4900 4905 Asp Ser Met Ser Tyr Glu Asp Gln Asp Ala Leu Phe Ala Tyr Thr 4910 4915 4920 Lys Arg Asn Val Ile Pro Thr Ile Thr Gln Met Asn Leu Lys Tyr 4925 4930 4935 Ala Ile Ser Ala Lys Asn Arg Ala Arg Thr Val Ala Gly Val Ser 4940 4945 4950 Ile Cys Ser Thr Met Thr Asn Arg Gln Phe Hes Gln Lys Leu Leu 4955 4960 4965 Lys Ser Ile Ala Ala Thr Arg Gly Ala Thr Val Val Ile Gly Thr 4970 4975 4980 Ser Lys Phe Tyr Gly Gly Trp Hes Asn Met Leu Lys Thr Val Tyr 4985 4990 4995 Ser Asp Val Glu Asn Pro Hes Leu Met Gly Trp Asp Tyr Pro Lys 5000 5005 5010 Cys Asp Arg Ala Met Pro Asn Met Leu Arg Ile Met Ala Ser Leu 5015 5020 5025 Val Leu Ala Arg Lys Hes Thr Thr Cys Cys Ser Leu Ser Hes Arg 5030 5035 5040 Phe Tyr Arg Leu Ala Asn Glu Cys Ala Gln Val Leu Ser Glu Met 5045 5050 5055 Val Met Cys Gly Gly Ser Leu Tyr Val Lys Pro Gly Gly Thr Ser 5060 5065 5070 Ser Gly Asp Ala Thr Thr Ala Tyr Ala Asn Ser Val Phe Asn Ile 5075 5080 5085 Cys Gln Ala Val Thr Ala Asn Val Asn Ala Leu Leu Ser Thr Asp 5090 5095 5100 Gly Asn Lys Ile Ala Asp Lys Tyr Val Arg Asn Leu Gln Hes Arg 5105 5110 5115 Leu Tyr Glu Cys Leu Tyr Arg Asn Arg Asp Val Asp Thr Asp Phe 5120 5125 5130 Val Asn Glu Phe Tyr Ala Tyr Leu Arg Lys Hes Phe Ser Met Met 5135 5140 5145 Ile Leu Ser Asp Asp Ala Val Val Cys Phe Asn Ser Thr Tyr Ala 5150 5155 5160 Ser Gln Gly Leu Val Ala Ser Ile Lys Asn Phe Lys Ser Val Leu 5165 5170 5175 Tyr Tyr Gln Asn Asn Val Phe Met Ser Glu Ala Lys Cys Trp Thr 5180 5185 5190 Glu Thr Asp Leu Thr Lys Gly Pro Hes Glu Phe Cys Ser Gln Hes 5195 5200 5205 Thr Met Leu Val Lys Gln Gly Asp Asp Tyr Val Tyr Leu Pro Tyr 5210 5215 5220 Pro Asp Pro Ser Arg Ile Leu Gly Ala Gly Cys Phe Val Asp Asp 5225 5230 5235 Ile Val Lys Thr Asp Gly Thr Leu Met Ile Glu Arg Phe Val Ser 5240 5245 5250 Leu Ala Ile Asp Ala Tyr Pro Leu Thr Lys Hes Pro Asn Gln Glu 5255 5260 5265 Tyr Ala Asp Val Phe Hes Leu Tyr Leu Gln Tyr Ile Arg Lys Leu 5270 5275 5280 Hes Asp Glu Leu Thr Gly Hes Met Leu Asp Met Tyr Ser Val Met 5285 5290 5295 Leu Thr Asn Asp Asn Thr Ser Arg Tyr Trp Glu Pro Glu Phe Tyr 5300 5305 5310 Glu Ala Met Tyr Thr Pro Hes Thr Val Leu Gln Ala Val Gly Ala 5315 5320 5325 Cys Val Leu Cys Asn Ser Gln Thr Ser Leu Arg Cys Gly Ala Cys 5330 5335 5340 Ile Arg Arg Pro Phe Leu Cys Cys Lys Cys Cys Tyr Asp Hes Val 5345 5350 5355 Ile Ser Thr Ser Hes Lys Leu Val Leu Ser Val Asn Pro Tyr Val 5360 5365 5370 Cys Asn Ala Pro Gly Cys Asp Val Thr Asp Val Thr Gln Leu Tyr 5375 5380 5385 Leu Gly Gly Met Ser Tyr Tyr Cys Lys Ser Hes Lys Pro Pro Ile 5390 5395 5400 Ser Phe Pro Leu Cys Ala Asn Gly Gln Val Phe Gly Leu Tyr Lys 5405 5410 5415 Asn Thr Cys Val Gly Ser Asp Asn Val Thr Asp Phe Asn Ala Ile 5420 5425 5430 Ala Thr Cys Asp Trp Thr Asn Ala Gly Asp Tyr Ile Leu Ala Asn 5435 5440 5445 Thr Cys Thr Glu Arg Leu Lys Leu Phe Ala Ala Glu Thr Leu Lys 5450 5455 5460 Ala Thr Glu Glu Thr Phe Lys Leu Ser Tyr Gly Ile Ala Thr Val 5465 5470 5475 Arg Glu Val Leu Ser Asp Arg Glu Leu Hes Leu Ser Trp Glu Val 5480 5485 5490 Gly Lys Pro Arg Pro Pro Leu Asn Arg Asn Tyr Val Phe Thr Gly 5495 5500 5505 Tyr Arg Val Thr Lys Asn Ser Lys Val Gln Ile Gly Glu Tyr Thr 5510 5515 5520 Phe Glu Lys Gly Asp Tyr Gly Asp Ala Val Val Tyr Arg Gly Thr 5525 5530 5535 Thr Thr Tyr Lys Leu Asn Val Gly Asp Tyr Phe Val Leu Thr Ser 5540 5545 5550 Hes Thr Val Met Pro Leu Ser Ala Pro Thr Leu Val Pro Gln Glu 5555 5560 5565 Hes Tyr Val Arg Ile Thr Gly Leu Tyr Pro Thr Leu Asn Ile Ser 5570 5575 5580 Asp Glu Phe Ser Ser Asn Val Ala Asn Tyr Gln Lys Val Gly Met 5585 5590 5595 Gln Lys Tyr Ser Thr Leu Gln Gly Pro Pro Gly Thr Gly Lys Ser 5600 5605 5610 Hes Phe Ala Ile Gly Leu Ala Leu Tyr Tyr Pro Ser Ala Arg Ile 5615 5620 5625 Val Tyr Thr Ala Cys Ser Hes Ala Ala Val Asp Ala Leu Cys Glu 5630 5635 5640 Lys Ala Leu Lys Tyr Leu Pro Ile Asp Lys Cys Ser Arg Ile Ile 5645 5650 5655 Pro Ala Arg Ala Arg Val Glu Cys Phe Asp Lys Phe Lys Val Asn 5660 5665 5670 Ser Thr Leu Glu Gln Tyr Val Phe Cys Thr Val Asn Ala Leu Pro 5675 5680 5685 Glu Thr Thr Ala Asp Ile Val Val Phe Asp Glu Ile Ser Met Ala 5690 5695 5700 Thr Asn Tyr Asp Leu Ser Val Val Asn Ala Arg Leu Arg Ala Lys 5705 5710 5715 Hes Tyr Val Tyr Ile Gly Asp Pro Ala Gln Leu Pro Ala Pro Arg 5720 5725 5730 Thr Leu Leu Thr Lys Gly Thr Leu Glu Pro Glu Tyr Phe Asn Ser 5735 5740 5745 Val Cys Arg Leu Met Lys Thr Ile Gly Pro Asp Met Phe Leu Gly 5750 5755 5760 Thr Cys Arg Arg Cys Pro Ala Glu Ile Val Asp Thr Val Ser Ala 5765 5770 5775 Leu Val Tyr Asp Asn Lys Leu Lys Ala Hes Lys Asp Lys Ser Ala 5780 5785 5790 Gln Cys Phe Lys Met Phe Tyr Lys Gly Val Ile Thr Hes Asp Val 5795 5800 5805 Ser Ser Ala Ile Asn Arg Pro Gln Ile Gly Val Val Arg Glu Phe 5810 5815 5820 Leu Thr Arg Asn Pro Ala Trp Arg Lys Ala Val Phe Ile Ser Pro 5825 5830 5835 Tyr Asn Ser Gln Asn Ala Val Ala Ser Lys Ile Leu Gly Leu Pro 5840 5845 5850 Thr Gln Thr Val Asp Ser Ser Gln Gly Ser Glu Tyr Asp Tyr Val 5855 5860 5865 Ile Phe Thr Gln Thr Thr Glu Thr Ala Hes Ser Cys Asn Val Asn 5870 5875 5880 Arg Phe Asn Val Ala Ile Thr Arg Ala Lys Val Gly Ile Leu Cys 5885 5890 5895 Ile Met Ser Asp Arg Asp Leu Tyr Asp Lys Leu Gln Phe Thr Ser 5900 5905 5910 Leu Glu Ile Pro Arg Arg Asn Val Ala Thr Leu Gln Ala Glu Asn 5915 5920 5925 Val Thr Gly Leu Phe Lys Asp Cys Ser Lys Val Ile Thr Gly Leu 5930 5935 5940 Hes Pro Thr Gln Ala Pro Thr Hes Leu Ser Val Asp Thr Lys Phe 5945 5950 5955 Lys Thr Glu Gly Leu Cys Val Asp Ile Pro Gly Ile Pro Lys Asp 5960 5965 5970 Met Thr Tyr Arg Arg Leu Ile Ser Met Met Gly Phe Lys Met Asn 5975 5980 5985 Tyr Gln Val Asn Gly Tyr Pro Asn Met Phe Ile Thr Arg Glu Glu 5990 5995 6000 Ala Ile Arg Hes Val Arg Ala Trp Ile Gly Phe Asp Val Glu Gly 6005 6010 6015 Cys Hes Ala Thr Arg Glu Ala Val Gly Thr Asn Leu Pro Leu Gln 6020 6025 6030 Leu Gly Phe Ser Thr Gly Val Asn Leu Val Ala Val Pro Thr Gly 6035 6040 6045 Tyr Val Asp Thr Pro Asn Asn Thr Asp Phe Ser Arg Val Ser Ala 6050 6055 6060 Lys Pro Pro Pro Gly Asp Gln Phe Lys Hes Leu Ile Pro Leu Met 6065 6070 6075 Tyr Lys Gly Leu Pro Trp Asn Val Val Arg Ile Lys Ile Val Gln 6080 6085 6090 Met Leu Ser Asp Thr Leu Lys Asn Leu Ser Asp Arg Val Val Phe 6095 6100 6105 Val Leu Trp Ala Hes Gly Phe Glu Leu Thr Ser Met Lys Tyr Phe 6110 6115 6120 Val Lys Ile Gly Pro Glu Arg Thr Cys Cys Leu Cys Asp Arg Arg 6125 6130 6135 Ala Thr Cys Phe Ser Thr Ala Ser Asp Thr Tyr Ala Cys Trp Hes 6140 6145 6150 Hes Ser Ile Gly Phe Asp Tyr Val Tyr Asn Pro Phe Met Ile Asp 6155 6160 6165 Val Gln Gln Trp Gly Phe Thr Gly Asn Leu Gln Ser Asn Hes Asp 6170 6175 6180 Leu Tyr Cys Gln Val Hes Gly Asn Ala Hes Val Ala Ser Cys Asp 6185 6190 6195 Ala Ile Met Thr Arg Cys Leu Ala Val Hes Glu Cys Phe Val Lys 6200 6205 6210 Arg Val Asp Trp Thr Ile Glu Tyr Pro Ile Ile Gly Asp Glu Leu 6215 6220 6225 Lys Ile Asn Ala Ala Cys Arg Lys Val Gln Hes Met Val Val Lys 6230 6235 6240 Ala Ala Leu Leu Ala Asp Lys Phe Pro Val Leu Hes Asp Ile Gly 6245 6250 6255 Asn Pro Lys Ala Ile Lys Cys Val Pro Gln Ala Asp Val Glu Trp 6260 6265 6270 Lys Phe Tyr Asp Ala Gln Pro Cys Ser Asp Lys Ala Tyr Lys Ile 6275 6280 6285 Glu Glu Leu Phe Tyr Ser Tyr Ala Thr Hes Ser Asp Lys Phe Thr 6290 6295 6300 Asp Gly Val Cys Leu Phe Trp Asn Cys Asn Val Asp Arg Tyr Pro 6305 6310 6315 Ala Asn Ser Ile Val Cys Arg Phe Asp Thr Arg Val Leu Ser Asn 6320 6325 6330 Leu Asn Leu Pro Gly Cys Asp Gly Gly Ser Leu Tyr Val Asn Lys 6335 6340 6345 Hes Ala Phe Hes Thr Pro Ala Phe Asp Lys Ser Ala Phe Val Asn 6350 6355 6360 Leu Lys Gln Leu Pro Phe Phe Tyr Tyr Ser Asp Ser Pro Cys Glu 6365 6370 6375 Ser Hes Gly Lys Gln Val Val Ser Asp Ile Asp Tyr Val Pro Leu 6380 6385 6390 Lys Ser Ala Thr Cys Ile Thr Arg Cys Asn Leu Gly Gly Ala Val 6395 6400 6405 Cys Arg Hes Hes Ala Asn Glu Tyr Arg Leu Tyr Leu Asp Ala Tyr 6410 6415 6420 Asn Met Met Ile Ser Ala Gly Phe Ser Leu Trp Val Tyr Lys Gln 6425 6430 6435 Phe Asp Thr Tyr Asn Leu Trp Asn Thr Phe Thr Arg Leu Gln Ser 6440 6445 6450 Leu Glu Asn Val Ala Phe Asn Val Val Asn Lys Gly Hes Phe Asp 6455 6460 6465 Gly Gln Gln Gly Glu Val Pro Val Ser Ile Ile Asn Asn Thr Val 6470 6475 6480 Tyr Thr Lys Val Asp Gly Val Asp Val Glu Leu Phe Glu Asn Lys 6485 6490 6495 Thr Thr Leu Pro Val Asn Val Ala Phe Glu Leu Trp Ala Lys Arg 6500 6505 6510 Asn Ile Lys Pro Val Pro Glu Val Lys Ile Leu Asn Asn Leu Gly 6515 6520 6525 Val Asp Ile Ala Ala Asn Thr Val Ile Trp Asp Tyr Lys Arg Asp 6530 6535 6540 Ala Pro Ala Hes Ile Ser Thr Ile Gly Val Cys Ser Met Thr Asp 6545 6550 6555 Ile Ala Lys Lys Pro Thr Glu Thr Ile Cys Ala Pro Leu Thr Val 6560 6565 6570 Phe Phe Asp Gly Arg Val Asp Gly Gln Val Asp Leu Phe Arg Asn 6575 6580 6585 Ala Arg Asn Gly Val Leu Ile Thr Glu Gly Ser Val Lys Gly Leu 6590 6595 6600 Gln Pro Ser Val Gly Pro Lys Gln Ala Ser Leu Asn Gly Val Thr 6605 6610 6615 Leu Ile Gly Glu Ala Val Lys Thr Gln Phe Asn Tyr Tyr Lys Lys 6620 6625 6630 Val Asp Gly Val Val Gln Gln Leu Pro Glu Thr Tyr Phe Thr Gln 6635 6640 6645 Ser Arg Asn Leu Gln Glu Phe Lys Pro Arg Ser Gln Met Glu Ile 6650 6655 6660 Asp Phe Leu Glu Leu Ala Met Asp Glu Phe Ile Glu Arg Tyr Lys 6665 6670 6675 Leu Glu Gly Tyr Ala Phe Glu Hes Ile Val Tyr Gly Asp Phe Ser 6680 6685 6690 Hes Ser Gln Leu Gly Gly Leu Hes Leu Leu Ile Gly Leu Ala Lys 6695 6700 6705 Arg Phe Lys Glu Ser Pro Phe Glu Leu Glu Asp Phe Ile Pro Met 6710 6715 6720 Asp Ser Thr Val Lys Asn Tyr Phe Ile Thr Asp Ala Gln Thr Gly 6725 6730 6735 Ser Ser Lys Cys Val Cys Ser Val Ile Asp Leu Leu Leu Asp Asp 6740 6745 6750 Phe Val Glu Ile Ile Lys Ser Gln Asp Leu Ser Val Val Ser Lys 6755 6760 6765 Val Val Lys Val Thr Ile Asp Tyr Thr Glu Ile Ser Phe Met Leu 6770 6775 6780 Trp Cys Lys Asp Gly Hes Val Glu Thr Phe Tyr Pro Lys Leu Gln 6785 6790 6795 Ser Ser Gln Ala Trp Gln Pro Gly Val Ala Met Pro Asn Leu Tyr 6800 6805 6810 Lys Met Gln Arg Met Leu Leu Glu Lys Cys Asp Leu Gln Asn Tyr 6815 6820 6825 Gly Asp Ser Ala Thr Leu Pro Lys Gly Ile Met Met Asn Val Ala 6830 6835 6840 Lys Tyr Thr Gln Leu Cys Gln Tyr Leu Asn Thr Leu Thr Leu Ala 6845 6850 6855 Val Pro Tyr Asn Met Arg Val Ile Hes Phe Gly Ala Gly Ser Asp 6860 6865 6870 Lys Gly Val Ala Pro Gly Thr Ala Val Leu Arg Gln Trp Leu Pro 6875 6880 6885 Thr Gly Thr Leu Leu Val Asp Ser Asp Leu Asn Asp Phe Val Ser 6890 6895 6900 Asp Ala Asp Ser Thr Leu Ile Gly Asp Cys Ala Thr Val Hes Thr 6905 6910 6915 Ala Asn Lys Trp Asp Leu Ile Ile Ser Asp Met Tyr Asp Pro Lys 6920 6925 6930 Thr Lys Asn Val Thr Lys Glu Asn Asp Ser Lys Glu Gly Phe Phe 6935 6940 6945 Thr Tyr Ile Cys Gly Phe Ile Gln Gln Lys Leu Ala Leu Gly Gly 6950 6955 6960 Ser Val Ala Ile Lys Ile Thr Glu Hes Ser Trp Asn Ala Asp Leu 6965 6970 6975 Tyr Lys Leu Met Gly Hes Phe Ala Trp Trp Thr Ala Phe Val Thr 6980 6985 6990 Asn Val Asn Ala Ser Ser Ser Glu Ala Phe Leu Ile Gly Cys Asn 6995 7000 7005 Tyr Leu Gly Lys Pro Arg Glu Gln Ile Asp Gly Tyr Val Met Hes 7010 7015 7020 Ala Asn Tyr Ile Phe Trp Arg Asn Thr Asn Pro Ile Gln Leu Ser 7025 7030 7035 Ser Tyr Ser Leu Phe Asp Met Ser Lys Phe Pro Leu Lys Leu Arg 7040 7045 7050 Gly Thr Ala Val Met Ser Leu Lys Glu Gly Gln Ile Asn Asp Met 7055 7060 7065 Ile Leu Ser Leu Leu Ser Lys Gly Arg Leu Ile Ile Arg Glu Asn 7070 7075 7080 Asn Arg Val Val Ile Ser Ser Asp Val Leu Val Asn Asn 7085 7090 7095 <210> 3 <211> 1273 <212> PRT <213> SARS-CoV2 <400> 3 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ser Gln Cys Val 1 5 10 15 Asn Leu Thr Thr Arg Thr Gln Leu Pro Pro Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Hes Val Ser Gly Thr Asn Gly Thr Lys Arg Phe Asp 65 70 75 80 Asn Pro Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu 85 90 95 Lys Ser Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser 100 105 110 Lys Thr Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile 115 120 125 Lys Val Cys Glu Phe Gln Phe Cys Asn Asp Pro Phe Leu Gly Val Tyr 130 135 140 Tyr Hes Lys Asn Asn Lys Ser Trp Met Glu Ser Glu Phe Arg Val Tyr 145 150 155 160 Ser Ser Ala Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu 165 170 175 Met Asp Leu Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Arg Glu Phe 180 185 190 Val Phe Lys Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr 195 200 205 Pro Ile Asn Leu Val Arg Asp Leu Pro Gln Gly Phe Ser Ala Leu Glu 210 215 220 Pro Leu Val Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Thr 225 230 235 240 Leu Leu Ala Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser 245 250 255 Gly Trp Thr Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro 260 265 270 Arg Thr Phe Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala 275 280 285 Val Asp Cys Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys 290 295 300 Ser Phe Thr Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Val 305 310 315 320 Gln Pro Thr Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys 325 330 335 Pro Phe Gly Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala 340 345 350 Trp Asn Arg Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Val Leu 355 360 365 Tyr Asn Ser Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro 370 375 380 Thr Lys Leu Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe 385 390 395 400 Val Ile Arg Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly 405 410 415 Lys Ile Ala Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys 420 425 430 Val Ile Ala Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn 435 440 445 Tyr Asn Tyr Leu Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe 450 455 460 Glu Arg Asp Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys 465 470 475 480 Asn Gly Val Glu Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly 485 490 495 Phe Gln Pro Thr Asn Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val 500 505 510 Leu Ser Phe Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys 515 520 525 Lys Ser Thr Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn 530 535 540 Gly Leu Thr Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu 545 550 555 560 Pro Phe Gln Gln Phe Gly Arg Asp Ile Ala Asp Thr Thr Asp Ala Val 565 570 575 Arg Asp Pro Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe 580 585 590 Gly Gly Val Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val 595 600 605 Ala Val Leu Tyr Gln Asp Val Asn Cys Thr Glu Val Pro Val Ala Ile 610 615 620 Hes Ala Asp Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser 625 630 635 640 Asn Val Phe Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Hes Val 645 650 655 Asn Asn Ser Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala 660 665 670 Ser Tyr Gln Thr Gln Thr Asn Ser Pro Arg Arg Ala Arg Ser Val Ala 675 680 685 Ser Gln Ser Ile Ile Ala Tyr Thr Met Ser Leu Gly Ala Glu Asn Ser 690 695 700 Val Ala Tyr Ser Asn Asn Ser Ile Ala Ile Pro Thr Asn Phe Thr Ile 705 710 715 720 Ser Val Thr Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val 725 730 735 Asp Cys Thr Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu 740 745 750 Leu Leu Gln Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr 755 760 765 Gly Ile Ala Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln 770 775 780 Val Lys Gln Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe 785 790 795 800 Asn Phe Ser Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser 805 810 815 Phe Ile Glu Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly 820 825 830 Phe Ile Lys Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp 835 840 845 Leu Ile Cys Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu 850 855 860 Leu Thr Asp Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly 865 870 875 880 Thr Ile Thr Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile 885 890 895 Pro Phe Ala Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr 900 905 910 Gln Asn Val Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn 915 920 925 Ser Ala Ile Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala 930 935 940 Leu Gly Lys Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn 945 950 955 960 Thr Leu Val Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val 965 970 975 Leu Asn Asp Ile Leu Ser Arg Leu Asp Lys Val Glu Ala Glu Val Gln 980 985 990 Ile Asp Arg Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val 995 1000 1005 Thr Gln Gln Leu Ile Arg Ala Ala Glu Ile Arg Ala Ser Ala Asn 1010 1015 1020 Leu Ala Ala Thr Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys 1025 1030 1035 Arg Val Asp Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro 1040 1045 1050 Gln Ser Ala Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val 1055 1060 1065 Pro Ala Gln Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes 1070 1075 1080 Asp Gly Lys Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn 1085 1090 1095 Gly Thr Hes Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln 1100 1105 1110 Ile Ile Thr Thr Asp Asn Thr Phe Val Ser Gly Asn Cys Asp Val 1115 1120 1125 Val Ile Gly Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro 1130 1135 1140 Glu Leu Asp Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn 1145 1150 1155 Hes Thr Ser Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn 1160 1165 1170 Ala Ser Val Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu 1175 1180 1185 Val Ala Lys Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu 1190 1195 1200 Gly Lys Tyr Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu 1205 1210 1215 Gly Phe Ile Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met 1220 1225 1230 Leu Cys Cys Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys 1235 1240 1245 Ser Cys Gly Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro 1250 1255 1260 Val Leu Lys Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 4 <211> 22 <212> ADN <213> Secuencia Artificial <220> <223> Secuencia Artificial <400> 4 tgactgtgaa cgttcgagat ga 22 <210> 5 <211> 11 <212> PRT <213> Secuencia Artificial <220> <223> Secuencia Artificial <400> 5 Lys Leu Lys Leu Leu Leu Leu Leu Lys Leu Lys 1 5 10 <210> 6 <211> 26 <212> ADN <213> Secuencia Artificial <220> <223> Secuencia Artificial <220> <221> diferentes_características <222> (1)..(26) <223> n=dideoxyinosina <400> 6 ncncncncnc ncncncncnc ncncnc 26 <210> 7 <211> 20 <212> ADN <213> Secuencia Artificial <220> <223> Secuencia Artificial <400> 7 tccatgacgt tcctgacgtt 20 <210> 8 <211> 24 <212> ADN <213> Secuencia Artificial <220> <223> Secuencia Artificial <400> 8 tcgtcgtttt gtcgttttgt cgtt 24 <210> 9 <211> 29867 <212> ADN <213> SARS-CoV2 <220> <221> diferentes_características <222> (11083)..(11083) <223> n es a, c, g, ó t <400> 9 attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct 60 gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact 120 cacgcagtat aattaataac taattactgt cgttgacagg acacgagtaa ctcgtctatc 180 ttctgcaggc tgcttacggt ttcgtccgtg ttgcagccga tcatcagcac atctaggttt 240 cgtccgggtg tgaccgaaag gtaagatgga gagccttgtc cctggtttca acgagaaaac 300 acacgtccaa ctcagtttgc ctgttttaca ggttcgcgac gtgctcgtac gtggctttgg 360 agactccgtg gaggaggtct tatcagaggc acgtcaacat cttaaagatg gcacttgtgg 420 cttagtagaa gttgaaaaag gcgttttgcc tcaacttgaa cagccctatg tgttcatcaa 480 acgttcggat gctcgaactg cacctcatgg tcatgttatg gttgagctgg tagcagaact 540 cgaaggcatt cagtacggtc gtagtggtga gacacttggt gtccttgtcc ctcatgtggg 600 cgaaatacca gtggcttacc gcaaggttct tcttcgtaag aacggtaata aaggagctgg 660 tggccatagt tacggcgccg atctaaagtc atttgactta ggcgacgagc ttggcactga 720 tccttatgaa gattttcaag aaaactggaa cactaaacat agcagtggtg ttacccgtga 780 actcatgcgt gagcttaacg gaggggcata cactcgctat gtcgataaca acttctgtgg 840 ccctgatggc taccctcttg agtgcattaa agaccttcta gcacgtgctg gtaaagcttc 900 atgcactttg tccgaacaac tggactttat tgacactaag aggggtgtat actgctgccg 960 tgaacatgag catgaaattg cttggtacac ggaacgttct gaaaagagct atgaattgca 1020 gacacctttt gaaattaaat tggcaaagaa atttgacacc ttcaatgggg aatgtccaaa 1080 ttttgtattt cccttaaatt ccataatcaa gactattcaa ccaagggttg aaaagaaaaa 1140 gcttgatggc tttatgggta gaattcgatc tgtctatcca gttgcgtcac caaatgaatg 1200 caaccaaatg tgcctttcaa ctctcatgaa gtgtgatcat tgtggtgaaa cttcatggca 1260 gacgggcgat tttgttaaag ccacttgcga attttgtggc actgagaatt tgactaaaga 1320 aggtgccact acttgtggtt acttacccca aaatgctgtt gttaaaattt attgtccagc 1380 atgtcacaat tcagaagtag gacctgagca tagtcttgcc gaataccata atgaatctgg 1440 cttgaaaacc attcttcgta agggtggtcg cactattgcc tttggaggct gtgtgttctc 1500 ttatgttggt tgccataaca agtgtgccta ttgggttcca cgtgctagcg ctaacatagg 1560 ttgtaaccat acaggtgttg ttggagaagg ttccgaaggt cttaatgaca accttcttga 1620 aatactccaa aaagagaaag tcaacatcaa tattgttggt gactttaaac ttaatgaaga 1680 gatcgccatt attttggcat ctttttctgc ttccacaagt gcttttgtgg aaactgtgaa 1740 aggtttggat tataaagcat tcaaacaaat tgttgaatcc tgtggtaatt ttaaagttac 1800 aaaaggaaaa gctaaaaaag gtgcctggaa tattggtgaa cagaaatcaa tactgagtcc 1860 tctttatgca tttgcatcag aggctgctcg tgttgtacga tcaattttct cccgcactct 1920 tgaaactgct caaaattctg tgcgtgtttt acagaaggcc gctataacaa tactagatgg 1980 aatttcacag tattcactga gactcattga tgctatgatg ttcacatctg atttggctac 2040 taacaatcta gttgtaatgg cctacattac aggtggtgtt gttcagttga cttcgcagtg 2100 gctaactaac atctttggca ctgtttatga aaaactcaaa cccgtccttg attggcttga 2160 agagaagttt aaggaaggtg tagagtttct tagagacggt tgggaaattg ttaaatttat 2220 ctcaacctgt gcttgtgaaa ttgtcggtgg acaaattgtc acctgtgcta aggaaattaa 2280 ggagagtgtt cagacattct ttaagcttgt aaataaattt ttggctttgt gtgctgactc 2340 tatcattatt ggtggagcta aacttaaagc cttgaattta ggtgaaacat ttgtcacgca 2400 ctcaaaggga ttgtacagaa agtgtgttaa atccagagaa gaaactggcc tactcatgcc 2460 tctaaaagcc ccaaaagaaa ttatcttctt agagggagaa acacttccca cagaagtgtt 2520 aacagaggaa gttgtcttga aaactggtga tttacaacca ttagaacaac ctactagtga 2580 agctgttgaa gctccattgg ttggtacacc agtttgtatt aacgggctta tgttgctcga 2640 aatcaaagac acagaaaagt actgtgccct tgcacctaat atgatggtaa caaacaatac 2700 cttcacactc aaaggcggtg caccaacaaa ggttactttt ggtgatgaca ctgtgataga 2760 agtgcaaggt tacaagagtg tgaatatcac ttttgaactt gatgaaagga ttgataaagt 2820 acttaatgag aagtgctctg cctatacagt tgaactcggt acagaagtaa atgagttcgc 2880 ctgtgttgtg gcagatgctg tcataaaaac tttgcaacca gtatctgaat tacttacacc 2940 actgggcatt gatttagatg agtggagtat ggctacatac tacttatttg atgagtctgg 3000 tgagtttaaa ttggcttcac atatgtattg ttctttctac cctccagatg aggatgaaga 3060 agaaggtgat tgtgaagaag aagagtttga gccatcaact caatatgagt atggtactga 3120 agatgattac caaggtaaac ctttggaatt tggtgccact tctgctgctc ttcaacctga 3180 agaagagcaa gaagaagatt ggttagatga tgatagtcaa caaactgttg gtcaacaaga 3240 cggcagtgag gacaatcaga caactactat tcaaacaatt gttgaggttc aacctcaatt 3300 agagatggaa cttacaccag ttgttcagac tattgaagtg aatagtttta gtggttattt 3360 aaaacttact gacaatgtat acattaaaaa tgcagacatt gtggaagaag ctaaaaaggt 3420 aaaaccaaca gtggttgtta atgcagccaa tgtttacctt aaacatggag gaggtgttgc 3480 aggagcctta aataaggcta ctaacaatgc catgcaagtt gaatctgatg attacatagc 3540 tactaatgga ccacttaaag tgggtggtag ttgtgtttta agcggacaca atcttgctaa 3600 acactgtctt catgttgtcg gcccaaatgt taacaaaggt gaagacattc aacttcttaa 3660 gagtgcttat gaaaatttta atcagcacga agttctactt gcaccattat tatcagctgg 3720 tatttttggt gctgacccta tacattcttt aagagtttgt gtagatactg ttcgcacaaa 3780 tgtctactta gctgtctttg ataaaaatct ctatgacaaa cttgtttcaa gctttttgga 3840 aatgaagagt gaaaagcaag ttgaacaaaa gatcgctgag attcctaaag aggaagttaa 3900 gccatttata actgaaagta aaccttcagt tgaacagaga aaacaagatg ataagaaaat 3960 caaagcttgt gttgaagaag ttacaacaac tctggaagaa actaagttcc tcacagaaaa 4020 cttgttactt tatattgaca ttaatggcaa tcttcatcca gattctgcca ctcttgttag 4080 tgacattgac atcactttct taaagaaaga tgctccatat atagtgggtg atgttgttca 4140 agagggtgtt ttaactgctg tggttatacc tactaaaaag gctggtggca ctactgaaat 4200 gctagcgaaa gctttgagaa aagtgccaac agacaattat ataaccactt acccgggtca 4260 gggtttaaat ggttacactg tagaggaggc aaagacagtg cttaaaaagt gtaaaagtgc 4320 cttttacatt ctaccatcta ttatctctaa tgagaagcaa gaaattcttg gaactgtttc 4380 ttggaatttg cgagaaatgc ttgcacatgc agaagaaaca cgcaaattaa tgcctgtctg 4440 tgtggaaact aaagccatag tttcaactat acagcgtaaa tataagggta ttaaaataca 4500 agagggtgtg gttgattatg gtgctagatt ttacttttac accagtaaaa caactgtagc 4560 gtcacttatc aacacactta acgatctaaa tgaaactctt gttacaatgc cacttggcta 4620 tgtaacacat ggcttaaatt tggaagaagc tgctcggtat atgagatctc tcaaagtgcc 4680 agctacagtt tctgtttctt cacctgatgc tgttacagcg tataatggtt atcttacttc 4740 ttcttctaaa acacctgaag aacattttat tgaaaccatc tcacttgctg gttcctataa 4800 agattggtcc tattctggac aatctacaca actaggtata gaatttctta agagaggtga 4860 taaaagtgta tattacacta gtaatcctac cacattccac ctagatggtg aagttatcac 4920 ctttgacaat cttaagacac ttctttcttt gagagaagtg aggactatta aggtgtttac 4980 aacagtagac aacattaacc tccacacgca agttgtggac atgtcaatga catatggaca 5040 acagtttggt ccaacttatt tggatggagc tgatgttact aaaataaaac ctcataattc 5100 acatgaaggt aaaacatttt atgttttacc taatgatgac actctacgtg ttgaggcttt 5160 tgagtactac cacacaactg atcctagttt tctgggtagg tacatgtcag cattaaatca 5220 cactaaaaag tggaaatacc cacaagttaa tggtttaact tctattaaat gggcagataa 5280 caactgttat cttgccactg cattgttaac actccaacaa atagagttga agtttaatcc 5340 acctgctcta caagatgctt attacagagc aagggctggt gaagctgcta acttttgtgc 5400 acttatctta gcctactgta ataagacagt aggtgagtta ggtgatgtta gagaaacaat 5460 gagttacttg tttcaacatg ccaatttaga ttcttgcaaa agagtcttga acgtggtgtg 5520 taaaacttgt ggacaacagc agacaaccct taagggtgta gaagctgtta tgtacatggg 5580 cacactttct tatgaacaat ttaagaaagg tgttcagata ccttgtacgt gtggtaaaca 5640 agctacaaaa tatctagtac aacaggagtc accttttgtt atgatgtcag caccacctgc 5700 tcagtatgaa cttaagcatg gtacatttac ttgtgctagt gagtacactg gtaattacca 5760 gtgtggtcac tataaacata taacttctaa agaaactttg tattgcatag acggtgcttt 5820 acttacaaag tcctcagaat acaaaggtcc tattacggat gttttctaca aagaaaacag 5880 ttacacaaca accataaaac cagttactta taaattggat ggtgttgttt gtacagaaat 5940 tgaccctaag ttggacaatt attataagaa agacaattct tatttcacag agcaaccaat 6000 tgatcttgta ccaaaccaac catatccaaa cgcaagcttc gataatttta agtttgtatg 6060 tgataatatc aaatttgctg atgatttaaa ccagttaact ggttataaga aacctgcttc 6120 aagagagctt aaagttacat ttttccctga cttaaatggt gatgtggtgg ctattgatta 6180 taaacactac acaccctctt ttaagaaagg agctaaattg ttacataaac ctattgtttg 6240 gcatgttaac aatgcaacta ataaagccac gtataaacca aatacctggt gtatacgttg 6300 tctttggagc acaaaaccag ttgaaacatc aaattcgttt gatgtactga agtcagagga 6360 cgcgcaggga atggataatc ttgcctgcga agatctaaaa ccagtctctg aagaagtagt 6420 ggaaaatcct accatacaga aagacgttct tgagtgtaat gtgaaaacta ccgaagttgt 6480 aggagacatt atacttaaac cagcaaataa tagtttaaaa attacagaag aggttggcca 6540 cacagatcta atggctgctt atgtagacaa ttctagtctt actattaaga aacctaatga 6600 attatctaga gtattaggtt tgaaaaccct tgctactcat ggtttagctg ctgttaatag 6660 tgtcccttgg gatactatag ctaattatgc taagcctttt cttaacaaag ttgttagtac 6720 aactactaac atagttacac ggtgtttaaa ccgtgtttgt actaattata tgccttattt 6780 ctttacttta ttgctacaat tgtgtacttt tactagaagt acaaattcta gaattaaagc 6840 atctatgccg actactatag caaagaatac tgttaagagt gtcggtaaat tttgtctaga 6900 ggcttcattt aattatttga agtcacctaa tttttctaaa ctgataaata ttataatttg 6960 gtttttacta ttaagtgttt gcctaggttc tttaatctac tcaaccgctg ctttaggtgt 7020 tttaatgtct aatttaggca tgccttctta ctgtactggt tacagagaag gctatttgaa 7080 ctctactaat gtcactattg caacctactg tactggttct ataccttgta gtgtttgtct 7140 tagtggttta gattctttag acacctatcc ttctttagaa actatacaaa ttaccatttc 7200 atcttttaaa tgggatttaa ctgcttttgg cttagttgca gagtggtttt tggcatatat 7260 tcttttcact aggtttttct atgtacttgg attggctgca atcatgcaat tgtttttcag 7320 ctattttgca gtacatttta ttagtaattc ttggcttatg tggttaataa ttaatcttgt 7380 acaaatggcc ccgatttcag ctatggttag aatgtacatc ttctttgcat cattttatta 7440 tgtatggaaa agttatgtgc atgttgtaga cggttgtaat tcatcaactt gtatgatgtg 7500 ttacaaacgt aatagagcaa caagagtcga atgtacaact attgttaatg gtgttagaag 7560 gtccttttat gtctatgcta atggaggtaa aggcttttgc aaactacaca attggaattg 7620 tgttaattgt gatacattct gtgctggtag tacatttatt agtgatgaag ttgcgagaga 7680 cttgtcacta cagtttaaaa gaccaataaa tcctactgac cagtcttctt acatcgttga 7740 tagtgttaca gtgaagaatg gttccatcca tctttacttt gataaagctg gtcaaaagac 7800 ttatgaaaga cattctctct ctcattttgt taacttagac aacctgagag ctaataacac 7860 taaaggttca ttgcctatta atgttatagt ttttgatggt aaatcaaaat gtgaagaatc 7920 atctgcaaaa tcagcgtctg tttactacag tcagcttatg tgtcaaccta tactgttact 7980 agatcaggca ttagtgtctg atgttggtga tagtgcggaa gttgcagtta aaatgtttga 8040 tgcttacgtt aatacgtttt catcaacttt taacgtacca atggaaaaac tcaaaacact 8100 agttgcaact gcagaagctg aacttgcaaa gaatgtgtcc ttagacaatg tcttatctac 8160 ttttatttca gcagctcggc aagggtttgt tgattcagat gtagaaacta aagatgttgt 8220 tgaatgtctt aaattgtcac atcaatctga catagaagtt actggcgata gttgtaataa 8280 ctatatgctc acctataaca aagttgaaaa catgacaccc cgtgaccttg gtgcttgtat 8340 tgactgtagt gcgcgtcata ttaatgcgca ggtagcaaaa agtcacaaca ttgctttgat 8400 atggaacgtt aaagatttca tgtcattgtc tgaacaacta cgaaaacaaa tacgtagtgc 8460 tgctaaaaag aataacttac cttttaagtt gacatgtgca actactagac aagttgttaa 8520 tgttgtaaca acaaagatag cacttaaggg tggtaaaatt gttaataatt ggttgaagca 8580 gttaattaaa gttacacttg tgttcctttt tgttgctgct attttctatt taataacacc 8640 tgttcatgtc atgtctaaac atactgactt ttcaagtgaa atcataggat acaaggctat 8700 tgatggtggt gtcactcgtg acatagcatc tacagatact tgttttgcta acaaacatgc 8760 tgattttgac acatggttta gccagcgtgg tggtagttat actaatgaca aagcttgccc 8820 attgattgct gcagtcataa caagagaagt gggttttgtc gtgcctggtt tgcctggcac 8880 gatattacgc acaactaatg gtgacttttt gcatttctta cctagagttt ttagtgcagt 8940 tggtaacatc tgttacacac catcaaaact tatagagtac actgactttg caacatcagc 9000 ttgtgttttg gctgctgaat gtacaatttt taaagatgct tctggtaagc cagtaccata 9060 ttgttatgat accaatgtac tagaaggttc tgttgcttat gaaagtttac gccctgacac 9120 acgttatgtg ctcatggatg gctctattat tcaatttcct aacacctacc ttgaaggttc 9180 tgttagagtg gtaacaactt ttgattctga gtactgtagg cacggcactt gtgaaagatc 9240 agaagctggt gtttgtgtat ctactagtgg tagatgggta cttaacaatg attattacag 9300 atctttacca ggagttttct gtggtgtaga tgctgtaaat ttacttacta atatgtttac 9360 accactaatt caacctattg gtgctttgga catatcagca tctatagtag ctggtggtat 9420 tgtagctatc gtagtaacat gccttgccta ctattttatg aggtttagaa gagcttttgg 9480 tgaatacagt catgtagttg cctttaatac tttactattc cttatgtcat tcactgtact 9540 ctgtttaaca ccagtttact cattcttacc tggtgtttat tctgttattt acttgtactt 9600 gacattttat cttactaatg atgtttcttt tttagcacat attcagtgga tggttatgtt 9660 cacaccttta gtacctttct ggataacaat tgcttatatc atttgtattt ccacaaagca 9720 tttctattgg ttctttagta attacctaaa gagacgtgta gtctttaatg gtgtttcctt 9780 tagtactttt gaagaagctg cgctgtgcac ctttttgtta aataaagaaa tgtatctaaa 9840 gttgcgtagt gatgtgctat tacctcttac gcaatataat agatacttag ctctttataa 9900 taagtacaag tattttagtg gagcaatgga tacaactagc tacagagaag ctgcttgttg 9960 tcatctcgca aaggctctca atgacttcag taactcaggt tctgatgttc tttaccaacc 10020 accacaaacc tctatcacct cagctgtttt gcagagtggt tttagaaaaa tggcattccc 10080 atctggtaaa gttgagggtt gtatggtaca agtaacttgt ggtacaacta cacttaacgg 10140 tctttggctt gatgacgtag tttactgtcc aagacatgtg atctgcacct ctgaagacat 10200 gcttaaccct aattatgaag atttactcat tcgtaagtct aatcataatt tcttggtaca 10260 ggctggtaat gttcaactca gggttattgg acattctatg caaaattgtg tacttaagct 10320 taaggttgat acagccaatc ctaagacacc taagtataag tttgttcgca ttcaaccagg 10380 acagactttt tcagtgttag cttgttacaa tggttcacca tctggtgttt accaatgtgc 10440 tatgaggccc aatttcacta ttaagggttc attccttaat ggttcatgtg gtagtgttgg 10500 ttttaacata gattatgact gtgtctcttt ttgttacatg caccatatgg aattaccaac 10560 tggagttcat gctggcacag acttagaagg taacttttat ggaccttttg ttgacaggca 10620 aacagcacaa gcagctggta cggacacaac tattacagtt aatgttttag cttggttgta 10680 cgctgctgtt ataaatggag acaggtggtt tctcaatcga tttaccacaa ctcttaatga 10740 ctttaacctt gtggctatga agtacaatta tgaacctcta acacaagacc atgttgacat 10800 actaggacct ctttctgctc aaactggaat tgccgtttta gatatgtgtg cttcattaaa 10860 agaattactg caaaatggta tgaatggacg taccatattg ggtagtgctt tattagaaga 10920 tgaatttaca ccttttgatg ttgttagaca atgctcaggt gttactttcc aaagtgcagt 10980 gaaaagaaca atcaagggta cacaccactg gttgttactc acaattttga cttcactttt 11040 agttttagtc cagagtactc aatggtcttt gttctttttt ttntatgaaa atgccttttt 11100 accttttgct atgggtatta ttgctatgtc tgcttttgca atgatgtttg tcaaacataa 11160 gcatgcattt ctctgtttgt ttttgttacc ttctcttgcc actgtagctt attttaatat 11220 ggtctatatg cctgctagtt gggtgatgcg tattatgaca tggttggata tggttgatac 11280 tagtttgtct ggttttaagc taaaagactg tgttatgtat gcatcagctg tagtgttact 11340 aatccttatg acagcaagaa ctgtgtatga tgatggtgct aggagagtgt ggacacttat 11400 gaatgtcttg acactcgttt ataaagttta ttatggtaat gctttagatc aagccatttc 11460 catgtgggct cttataatct ctgttacttc taactactca ggtgtagtta caactgtcat 11520 gtttttggcc agaggtattg tttttatgtg tgttgagtat tgccctattt tcttcataac 11580 tggtaataca cttcagtgta taatgctagt ttattgtttc ttaggctatt tttgtacttg 11640 ttactttggc ctcttttgtt tactcaaccg ctactttaga ctgactcttg gtgtttatga 11700 ttacttagtt tctacacagg agtttagata tatgaattca cagggactac tcccacccaa 11760 gaatagcata gatgccttca aactcaacat taaattgttg ggtgttggtg gcaaaccttg 11820 tatcaaagta gccactgtac agtctaaaat gtcagatgta aagtgcacat cagtagtctt 11880 actctcagtt ttgcaacaac tcagagtaga atcatcatct aaattgtggg ctcaatgtgt 11940 ccagttacac aatgacattc tcttagctaa agatactact gaagcctttg aaaaaatggt 12000 ttcactactt tctgttttgc tttccatgca gggtgctgta gacataaaca agctttgtga 12060 agaaatgctg gacaacaggg caaccttaca agctatagcc tcagagttta gttcccttcc 12120 atcatatgca gcttttgcta ctgctcaaga agcttatgag caggctgttg ctaatggtga 12180 ttctgaagtt gttcttaaaa agttgaagaa gtctttgaat gtggctaaat ctgaatttga 12240 ccgtgatgca gccatgcaac gtaagttgga aaagatggct gatcaagcta tgacccaaat 12300 gtataaacag gctagatctg aggacaagag ggcaaaagtt actagtgcta tgcagacaat 12360 gcttttcact atgcttagaa agttggataa tgatgcactc aacaacatta tcaacaatgc 12420 aagagatggt tgtgttccct tgaacataat acctcttaca acagcagcca aactaatggt 12480 tgtcatacca gactataaca catataaaaa tacgtgtgat ggtacaacat ttacttatgc 12540 atcagcattg tgggaaatcc aacaggttgt agatgcagat agtaaaattg ttcaacttag 12600 tgaaattagt atggacaatt cacctaattt agcatggcct cttattgtaa cagctttaag 12660 ggccaattct gctgtcaaat tacagaataa tgagcttagt cctgttgcac tacgacagat 12720 gtcttgtgct gccggtacta cacaaactgc ttgcactgat gacaatgcgt tagcttacta 12780 caacacaaca aagggaggta ggtttgtact tgcactgtta tccgatttac aggatttgaa 12840 atgggctaga ttccctaaga gtgatggaac tggtactatc tatacagaac tggaaccacc 12900 ttgtaggttt gttacagaca cacctaaagg tcctaaagtg aagtatttat actttattaa 12960 aggattaaac aacctaaata gaggtatggt acttggtagt ttagctgcca cagtacgtct 13020 acaagctggt aatgcaacag aagtgcctgc caattcaact gtattatctt tctgtgcttt 13080 tgctgtagat gctgctaaag cttacaaaga ttatctagct agtgggggac aaccaatcac 13140 taattgtgtt aagatgttgt gtacacacac tggtactggt caggcaataa cagttacacc 13200 ggaagccaat atggatcaag aatcctttgg tggtgcatcg tgttgtctgt actgccgttg 13260 ccacatagat catccaaatc ctaaaggatt ttgtgactta aaaggtaagt atgtacaaat 13320 acctacaact tgtgctaatg accctgtggg ttttacactt aaaaacacag tctgtaccgt 13380 ctgcggtatg tggaaaggtt atggctgtag ttgtgatcaa ctccgcgaac ccatgcttca 13440 gtcagctgat gcacaatcgt ttttaaacgg gtttgcggtg taagtgcagc ccgtcttaca 13500 ccgtgcggca caggcactag tactgatgtc gtatacaggg cttttgacat ctacaatgat 13560 aaagtagctg gttttgctaa attcctaaaa actaattgtt gtcgcttcca agaaaaggac 13620 gaagatgaca atttaattga ttcttacttt gtagttaaga gacacacttt ctctaactac 13680 caacatgaag aaacaattta taatttactt aaggattgtc cagctgttgc taaacatgac 13740 ttctttaagt ttagaataga cggtgacatg gtaccacata tatcacgtca acgtcttact 13800 aaatacacaa tggcagacct cgtctatgct ttaaggcatt ttgatgaagg taattgtgac 13860 acattaaaag aaatacttgt cacatacaat tgttgtgatg atgattattt caataaaaag 13920 gactggtatg attttgtaga aaacccagat atattacgcg tatacgccaa cttaggtgaa 13980 cgtgtacgcc aagctttgtt aaaaacagta caattctgtg atgccatgcg aaatgctggt 14040 attgttggtg tactgacatt agataatcaa gatctcaatg gtaactggta tgatttcggt 14100 gatttcatac aaaccacgcc aggtagtgga gttcctgttg tagattctta ttattcattg 14160 ttaatgccta tattaacctt gaccagggct ttaactgcag agtcacatgt tgacactgac 14220 ttaacaaagc cttacattaa gtgggatttg ttaaaatatg acttcacgga agagaggtta 14280 aaactctttg accgttattt taaatattgg gatcagacat accacccaaa ttgtgttaac 14340 tgtttggatg acagatgcat tctgcattgt gcaaacttta atgttttatt ctctacagtg 14400 ttcccaccta caagttttgg accactagtg agaaaaatat ttgttgatgg tgttccattt 14460 gtagtttcaa ctggatacca cttcagagag ctaggtgttg tacataatca ggatgtaaac 14520 ttacatagct ctagacttag ttttaaggaa ttacttgtgt atgctgctga ccctgctatg 14580 cacgctgctt ctggtaatct attactagat aaacgcacta cgtgcttttc agtagctgca 14640 cttactaaca atgttgcttt tcaaactgtc aaacccggta attttaacaa agacttctat 14700 gactttgctg tgtctaaggg tttctttaag gaaggaagtt ctgttgaatt aaaacacttc 14760 ttctttgctc aggatggtaa tgctgctatc agcgattatg actactatcg ttataatcta 14820 ccaacaatgt gtgatatcag acaactacta tttgtagttg aagttgttga taagtacttt 14880 gattgttacg atggtggctg tattaatgct aaccaagtca tcgtcaacaa cctagacaaa 14940 tcagctggtt ttccatttaa taaatggggt aaggctagac tttattatga ttcaatgagt 15000 tatgaggatc aagatgcact tttcgcatat acaaaacgta atgtcatccc tactataact 15060 caaatgaatc ttaagtatgc cattagtgca aagaatagag ctcgcaccgt agctggtgtc 15120 tctatctgta gtactatgac caatagacag tttcatcaaa aattattgaa atcaatagcc 15180 gccactagag gagctactgt agtaattgga acaagcaaat tctatggtgg ttggcacaac 15240 atgttaaaaa ctgtttatag tgatgtagaa aaccctcacc ttatgggttg ggattatcct 15300 aaatgtgata gagccatgcc taacatgctt agaattatgg cctcacttgt tcttgctcgc 15360 aaacatacaa cgtgttgtag cttgtcacac cgtttctata gattagctaa tgagtgtgct 15420 caagtattga gtgaaatggt catgtgtggc ggttcactat atgttaaacc aggtggaacc 15480 tcatcaggag atgccacaac tgcttatgct aatagtgttt ttaacatttg tcaagctgtc 15540 acggccaatg ttaatgcact tttatctact gatggtaaca aaattgccga taagtatgtc 15600 cgcaatttac aacacagact ttatgagtgt ctctatagaa atagagatgt tgacacagac 15660 tttgtgaatg agttttacgc atatttgcgt aaacatttct caatgatgat actctctgac 15720 gatgctgttg tgtgtttcaa tagcacttat gcatctcaag gtctagtggc tagcataaag 15780 aactttaagt cagttcttta ttatcaaaac aatgttttta tgtctgaagc aaaatgttgg 15840 actgagactg accttactaa aggacctcat gaattttgct ctcaacatac aatgctagtt 15900 aaacagggtg atgattatgt gtaccttcct tacccagatc catcaagaat cctaggggcc 15960 ggctgttttg tagatgatat cgtaaaaaca gatggtacac ttatgattga acggttcgtg 16020 tctttagcta tagatgctta cccacttact aaacatccta atcaggagta tgctgatgtc 16080 tttcatttgt acttacaata cataagaaag ctacatgatg agttaacagg acacatgtta 16140 gacatgtatt ctgttatgct tactaatgat aacacttcaa ggtattggga acctgagttt 16200 tatgaggcta tgtacacacc gcatacagtc ttacaggctg ttggggcttg tgttctttgc 16260 aattcacaga cttcattaag atgtggtgct tgcatacgta gaccattctt atgttgtaaa 16320 tgctgttacg accatgtcat atcaacatca cataaattag tcttgtctgt taatccgtat 16380 gtttgcaatg ctccaggttg tgatgtcaca gatgtgactc aactttactt aggaggtatg 16440 agctattatt gtaaatcaca taaaccaccc attagttttc cattgtgtgc taatggacaa 16500 gtttttggtt tatataaaaa tacatgtgtt ggtagcgata atgttactga ctttaatgca 16560 attgcaacat gtgactggac aaatgctggt gattacattt tagctaacac ctgtactgaa 16620 agactcaagc tttttgcagc agaaacgctc aaagctactg aggagacatt taaactgtct 16680 tatggtattg ctactgtacg tgaagtgctg tctgacagag aattacatct ttcatgggaa 16740 gttggtaaac ctagaccacc acttaaccga aattatgtct ttactggtta tcgtgtaact 16800 aaaaacagta aagtacaaat aggagagtac acctttgaaa aaggtgacta tggtgatgct 16860 gttgtttacc gaggtacaac aacttacaaa ttaaatgttg gtgattattt tgtgctgaca 16920 tcacatacag taatgccatt aagtgcacct acactagtgc cacaagagca ctatgttaga 16980 attactggct tatacccaac actcaatatc tcagatgagt tttctagcaa tgttgcaaat 17040 tatcaaaagg ttggtatgca aaagtattct acactccagg gaccacctgg tactggtaag 17100 agtcattttg ctattggcct agctctctac tacccttctg ctcgcatagt gtatacagct 17160 tgctctcatg ccgctgttga tgcactatgt gagaaggcat taaaatattt gcctatagat 17220 aaatgtagta gaattatacc tgcacgtgct cgtgtagagt gttttgataa attcaaagtg 17280 aattcaacat tagaacagta tgtcttttgt actgtaaatg cattgcctga gacgacagca 17340 gatatagttg tctttgatga aatttcaatg gccacaaatt atgatttgag tgttgtcaat 17400 gccagattac gtgctaagca ctatgtgtac attggcgacc ctgctcaatt acctgcacca 17460 cgcacattgc taactaaggg cacactagaa ccagaatatt tcaattcagt gtgtagactt 17520 atgaaaacta taggtccaga catgttcctc ggaacttgtc ggcgttgtcc tgctgaaatt 17580 gttgacactg tgagtgcttt ggtttatgat aataagctta aagcacataa agacaaatca 17640 gctcaatgct ttaaaatgtt ttataagggt gttatcacgc atgatgtttc atctgcaatt 17700 aacaggccac aaataggcgt ggtaagagaa ttccttacac gtaaccctgc ttggagaaaa 17760 gctgtcttta tttcacctta taattcacag aatgctgtag cctcaaagat tttgggacta 17820 ccaactcaaa ctgttgattc atcacagggc tcagaatatg actatgtcat attcactcaa 17880 accactgaaa cagctcactc ttgtaatgta aacagattta atgttgctat taccagagca 17940 aaagtaggca tactttgcat aatgtctgat agagaccttt atgacaagtt gcaatttaca 18000 agtcttgaaa ttccacgtag gaatgtggca actttacaag ctgaaaatgt aacaggactc 18060 tttaaagatt gtagtaaggt aatcactggg ttacatccta cacaggcacc tacacacctc 18120 agtgttgaca ctaaattcaa aactgaaggt ttatgtgttg acatacctgg catacctaag 18180 gacatgacct atagaagact catctctatg atgggtttta aaatgaatta tcaagttaat 18240 ggttacccta acatgtttat cacccgcgaa gaagctataa gacatgtacg tgcatggatt 18300 ggcttcgatg tcgaggggtg tcatgctact agagaagctg ttggtaccaa tttaccttta 18360 cagctaggtt tttctacagg tgttaaccta gttgctgtac ctacaggtta tgttgataca 18420 cctaataata cagatttttc cagagttagt gctaaaccac cgcctggaga tcaatttaaa 18480 cacctcatac cacttatgta caaaggactt ccttggaatg tagtgcgtat aaagattgta 18540 caaatgttaa gtgacacact taaaaatctc tctgacagag tcgtatttgt cttatgggca 18600 catggctttg agttgacatc tatgaagtat tttgtgaaaa taggacctga gcgcacctgt 18660 tgtctatgtg atagacgtgc cacatgcttt tccactgctt cagacactta tgcctgttgg 18720 catcattcta ttggatttga ttacgtctat aatccgttta tgattgatgt tcaacaatgg 18780 ggttttacag gtaacctaca aagcaaccat gatctgtatt gtcaagtcca tggtaatgca 18840 catgtagcta gttgtgatgc aatcatgact aggtgtctag ctgtccacga gtgctttgtt 18900 aagcgtgttg actggactat tgaatatcct ataattggtg atgaactgaa gattaatgcg 18960 gcttgtagaa aggttcaaca catggttgtt aaagctgcat tattagcaga caaattccca 19020 gttcttcacg acattggtaa ccctaaagct attaagtgtg tacctcaagc tgatgtagaa 19080 tggaagttct atgatgcaca gccttgtagt gacaaagctt ataaaataga agaattattc 19140 tattcttatg ccacacattc tgacaaattc acagatggtg tatgcctatt ttggaattgc 19200 aatgtcgata gatatcctgc taattccatt gtttgtagat ttgacactag agtgctatct 19260 aaccttaact tgcctggttg tgatggtggc agtttgtatg taaataaaca tgcattccac 19320 acaccagctt ttgataaaag tgcttttgtt aatttaaaac aattaccatt tttctattac 19380 tctgacagtc catgtgagtc tcatggaaaa caagtagtgt cagatataga ttatgtacca 19440 ctaaagtctg ctacgtgtat aacacgttgc aatttaggtg gtgctgtctg tagacatcat 19500 gctaatgagt acagattgta tctcgatgct tataacatga tgatctcagc tggctttagc 19560 ttgtgggttt acaaacaatt tgatacttat aacctctgga acacttttac aagacttcag 19620 agtttagaaa atgtggcttt taatgttgta aataagggac actttgatgg acaacagggt 19680 gaagtaccag tttctatcat taataacact gtttacacaa aagttgatgg tgttgatgta 19740 gaattgtttg aaaataaaac aacattacct gttaatgtag catttgagct ttgggctaag 19800 cgcaacatta aaccagtacc agaggtgaaa atactcaata atttgggtgt ggacattgct 19860 gctaatactg tgatctggga ctacaaaaga gatgctccag cacatatatc tactattggt 19920 gtttgttcta tgactgacat agccaagaaa ccaactgaaa cgatttgtgc accactcact 19980 gtcttttttg atggtagagt tgatggtcaa gtagacttat ttagaaatgc ccgtaatggt 20040 gttcttatta cagaaggtag tgttaaaggt ttacaaccat ctgtaggtcc caaacaagct 20100 agtcttaatg gagtcacatt aattggagaa gccgtaaaaa cacagttcaa ttattataag 20160 aaagttgatg gtgttgtcca acaattacct gaaacttact ttactcagag tagaaattta 20220 caagaattta aacccaggag tcaaatggaa attgatttct tagaattagc tatggatgaa 20280 ttcattgaac ggtataaatt agaaggctat gccttcgaac atatcgttta tggagatttt 20340 agtcatagtc agttaggtgg tttacatcta ctgattggac tagctaaacg ttttaaggaa 20400 tcaccttttg aattagaaga ttttattcct atggacagta cagttaaaaa ctatttcata 20460 acagatgcgc aaacaggttc atctaagtgt gtgtgttctg ttattgattt attacttgat 20520 gattttgttg aaataataaa atcccaagat ttatctgtag tttctaaggt tgtcaaagtg 20580 actattgact atacagaaat ttcatttatg ctttggtgta aagatggcca tgtagaaaca 20640 ttttacccaa aattacaatc tagtcaagcg tggcaaccgg gtgttgctat gcctaatctt 20700 tacaaaatgc aaagaatgct attagaaaag tgtgaccttc aaaattatgg tgatagtgca 20760 acattaccta aaggcataat gatgaatgtc gcaaaatata ctcaactgtg tcaatattta 20820 aacacattaa cattagctgt accctataat atgagagtta tacattttgg tgctggttct 20880 gataaaggag ttgcaccagg tacagctgtt ttaagacagt ggttgcctac gggtacgctg 20940 cttgtcgatt cagatcttaa tgactttgtc tctgatgcag attcaacttt gattggtgat 21000 tgtgcaactg tacatacagc taataaatgg gatctcatta ttagtgatat gtacgaccct 21060 aagactaaaa atgttacaaa agaaaatgac tctaaagagg gttttttcac ttacatttgt 21120 gggtttatac aacaaaagct agctcttgga ggttccgtgg ctataaagat aacagaacat 21180 tcttggaatg ctgatcttta taagctcatg ggacacttcg catggtggac agcctttgtt 21240 actaatgtga atgcgtcatc atctgaagca tttttaattg gatgtaatta tcttggcaaa 21300 ccacgcgaac aaatagatgg ttatgtcatg catgcaaatt acatattttg gaggaataca 21360 aatccaattc agttgtcttc ctattcttta tttgacatga gtaaatttcc ccttaaatta 21420 aggggtactg ctgttatgtc tttaaaagaa ggtcaaatca atgatatgat tttatctctt 21480 cttagtaaag gtagacttat aattagagaa aacaacagag ttgttatttc tagtgatgtt 21540 cttgttaaca actaaacgaa caatgtttgt ttttcttgtt ttattgccac tagtctctag 21600 tcagtgtgtt aatcttacaa ccagaactca attaccccct gcatacacta attctttcac 21660 acgtggtgtt tattaccctg acaaagtttt cagatcctca gttttacatt caactcagga 21720 cttgttctta cctttctttt ccaatgttac ttggttccat gctatacatg tctctgggac 21780 caatggtact aagaggtttg ataaccctgt cctaccattt aatgatggtg tttattttgc 21840 ttccactgag aagtctaaca taataagagg ctggattttt ggtactactt tagattcgaa 21900 gacccagtcc ctacttattg ttaataacgc tactaatgtt gttattaaag tctgtgaatt 21960 tcaattttgt aatgatccat ttttgggtgt ttattaccac aaaaacaaca aaagttggat 22020 ggaaagtgag ttcagagttt attctagtgc gaataattgc acttttgaat atgtctctca 22080 gccttttctt atggaccttg aaggaaaaca gggtaatttc aaaaatctta gggaatttgt 22140 gtttaagaat attgatggtt attttaaaat atattctaag cacacgccta ttaatttagt 22200 gcgtgatctc cctcagggtt tttcggcttt agaaccattg gtagatttgc caataggtat 22260 taacatcact aggtttcaaa ctttacttgc tttacataga agttatttga ctcctggtga 22320 ttcttcttca ggttggacag ctggtgctgc agcttattat gtgggttatc ttcaacctag 22380 gacttttcta ttaaaatata atgaaaatgg aaccattaca gatgctgtag actgtgcact 22440 tgaccctctc tcagaaacaa agtgtacgtt gaaatccttc actgtagaaa aaggaatcta 22500 tcaaacttct aactttagag tccaaccaac agaatctatt gttagatttc ctaatattac 22560 aaacttgtgc ccttttggtg aagtttttaa cgccaccaga tttgcatctg tttatgcttg 22620 gaacaggaag agaatcagca actgtgttgc tgattattct gtcctatata attccgcatc 22680 attttccact tttaagtgtt atggagtgtc tcctactaaa ttaaatgatc tctgctttac 22740 taatgtctat gcagattcat ttgtaattag aggtgatgaa gtcagacaaa tcgctccagg 22800 gcaaactgga aagattgctg attataatta taaattacca gatgatttta caggctgcgt 22860 tatagcttgg aattctaaca atcttgattc taaggttggt ggtaattata attacctgta 22920 tagattgttt aggaagtcta atctcaaacc ttttgagaga gatatttcaa ctgaaatcta 22980 tcaggccggt agcacacctt gtaatggtgt tgaaggtttt aattgttact ttcctttaca 23040 atcatatggt ttccaaccca ctaatggtgt tggttaccaa ccatacagag tagtagtact 23100 ttcttttgaa cttctacatg caccagcaac tgtttgtgga cctaaaaagt ctactaattt 23160 ggttaaaaac aaatgtgtca atttcaactt caatggttta acaggcacag gtgttcttac 23220 tgagtctaac aaaaagtttc tgcctttcca acaatttggc agagacattg ctgacactac 23280 tgatgctgtc cgtgatccac agacacttga gattcttgac attacaccat gttcttttgg 23340 tggtgtcagt gttataacac caggaacaaa tacttctaac caggttgctg ttctttatca 23400 ggatgttaac tgcacagaag tccctgttgc tattcatgca gatcaactta ctcctacttg 23460 gcgtgtttat tctacaggtt ctaatgtttt tcaaacacgt gcaggctgtt taataggggc 23520 tgaacatgtc aacaactcat atgagtgtga catacccatt ggtgcaggta tatgcgctag 23580 ttatcagact cagactaatt ctcctcggcg ggcacgtagt gtagctagtc aatccatcat 23640 tgcctacact atgtcacttg gtgcagaaaa ttcagttgct tactctaata actctattgc 23700 catacccaca aattttacta ttagtgttac cacagaaatt ctaccagtgt ctatgaccaa 23760 gacatcagta gattgtacaa tgtacatttg tggtgattca actgaatgca gcaatctttt 23820 gttgcaatat ggcagttttt gtacacaatt aaaccgtgct ttaactggaa tagctgttga 23880 acaagacaaa aacacccaag aagtttttgc acaagtcaaa caaatttaca aaacaccacc 23940 aattaaagat tttggtggtt ttaatttttc acaaatatta ccagatccat caaaaccaag 24000 caagaggtca tttattgaag atctactttt caacaaagtg acacttgcag atgctggctt 24060 catcaaacaa tatggtgatt gccttggtga tattgctgct agagacctca tttgtgcaca 24120 aaagtttaac ggccttactg ttttgccacc tttgctcaca gatgaaatga ttgctcaata 24180 cacttctgca ctgttagcgg gtacaatcac ttctggttgg acctttggtg caggtgctgc 24240 attacaaata ccatttgcta tgcaaatggc ttataggttt aatggtattg gagttacaca 24300 gaatgttctc tatgagaacc aaaaattgat tgccaaccaa tttaatagtg ctattggcaa 24360 aattcaagac tcactttctt ccacagcaag tgcacttgga aaacttcaag atgtggtcaa 24420 ccaaaatgca caagctttaa acacgcttgt taaacaactt agctccaatt ttggtgcaat 24480 ttcaagtgtt ttaaatgata tcctttcacg tcttgacaaa gttgaggctg aagtgcaaat 24540 tgataggttg atcacaggca gacttcaaag tttgcagaca tatgtgactc aacaattaat 24600 tagagctgca gaaatcagag cttctgctaa tcttgctgct actaaaatgt cagagtgtgt 24660 acttggacaa tcaaaaagag ttgatttttg tggaaagggc tatcatctta tgtccttccc 24720 tcagtcagca cctcatggtg tagtcttctt gcatgtgact tatgtccctg cacaagaaaa 24780 gaacttcaca actgctcctg ccatttgtca tgatggaaaa gcacactttc ctcgtgaagg 24840 tgtctttgtt tcaaatggca cacactggtt tgtaacacaa aggaattttt atgaaccaca 24900 aatcattact acagacaaca catttgtgtc tggtaactgt gatgttgtaa taggaattgt 24960 caacaacaca gtttatgatc ctttgcaacc tgaattagac tcattcaagg aggagttaga 25020 taaatatttt aagaatcata catcaccaga tgttgattta ggtgacatct ctggcattaa 25080 tgcttcagtt gtaaacattc aaaaagaaat tgaccgcctc aatgaggttg ccaagaattt 25140 aaatgaatct ctcatcgatc tccaagaact tggaaagtat gagcagtata taaaatggcc 25200 atggtacatt tggctaggtt ttatagctgg cttgattgcc atagtaatgg tgacaattat 25260 gctttgctgt atgaccagtt gctgtagttg tctcaagggc tgttgttctt gtggatcctg 25320 ctgcaaattt gatgaagacg actctgagcc agtgctcaaa ggagtcaaat tacattacac 25380 ataaacgaac ttatggattt gtttatgaga atcttcacaa ttggaactgt aactttgaag 25440 caaggtgaaa tcaaggatgc tactccttca gattttgttc gcgctactgc aacgataccg 25500 atacaagcct cactcccttt cggatggctt attgttggcg ttgcacttct tgctgttttt 25560 cagagcgctt ccaaaatcat aaccctcaaa aagagatggc aactagcact ctccaagggt 25620 gttcactttg tttgcaactt gctgttgttg tttgtaacag tttactcaca ccttttgctc 25680 gttgctgctg gccttgaagc cccttttctc tatctttatg ctttagtcta cttcttgcag 25740 agtataaact ttgtaagaat aataatgagg ctttggcttt gctggaaatg ccgttccaaa 25800 aacccattac tttatgatgc caactatttt ctttgctggc atactaattg ttacgactat 25860 tgtatacctt acaatagtgt aacttcttca attgtcatta cttcaggtga tggcacaaca 25920 agtcctattt ctgaacatga ctaccagatt ggtggttata ctgaaaaatg ggaatctgga 25980 gtaaaagact gtgttgtatt acacagttac ttcacttcag actattacca gctgtactca 26040 actcaattga gtacagacac tggtgttgaa catgttacct tcttcatcta caataaaatt 26100 gttgatgagc ctgaagaaca tgtccaaatt cacacaatcg acgtttcatc cggagttgtt 26160 aatccagtaa tggaaccaat ttatgatgaa ccgacgacga ctactagcgt gcctttgtaa 26220 gcacaagctg atgagtacga acttatgtac tcattcgttt cggaagagac aggtacgtta 26280 atagttaata gcgtacttct ttttcttgct ttcgtggtat tcttgctagt tacactagcc 26340 atccttactg cgcttcgatt gtgtgcgtac tgctgcaata ttgttaacgt gagtcttgta 26400 aaaccttctt tttacgttta ctctcgtgtt aaaaatctga attcttctag agttcctgat 26460 cttctggtct aaacgaacta aatattatat tagtttttct gtttggaact ttaattttag 26520 ccatggcaga ttccaacggt actattaccg ttgaagagct taaaaagctc cttgaacaat 26580 ggaacctagt aataggtttc ctattcctta catggatttg tcttctacaa tttgcctatg 26640 ccaacaggaa taggtttttg tatataatta agttaatttt cctctggctg ttatggccag 26700 taactttagc ttgttttgtg cttgctgctg tttacagaat aaattggatc accggtggaa 26760 ttgctatcgc aatggcttgt cttgtaggct tgatgtggct cagctacttc attgcttctt 26820 tcagactgtt tgcgcgtacg cgttccatgt ggtcattcaa tccagaaact aacattcttc 26880 tcaacgtgcc actccatggc actattctga ccagaccgct tctagaaagt gaactcgtaa 26940 tcggagctgt gatccttcgt ggacatcttc gtattgctgg acaccatcta ggacgctgtg 27000 acatcaagga cctgcctaaa gaaatcactg ttgctacatc acgaacgctt tcttattaca 27060 aattgggagc ttcgcagcgt gtagcaggtg actcaggttt tgctgcatac agtcgctaca 27120 ggattggcaa ctataaatta aacacagacc attccagtag cagtgacaat attgctttgc 27180 ttgtacagta agtgacaaca gatgtttcat ctcgttgact ttcaggttac tatagcagag 27240 atattactaa ttattatgag gacttttaaa gtttccattt ggaatcttga ttacatcata 27300 aacctcataa ttaaaaattt atctaagtca ctaactgaga ataaatattc tcaattagat 27360 gaagagcaac caatggagat tgattaaacg aacatgaaaa ttattctttt cttggcactg 27420 ataacactcg ctacttgtga gctttatcac taccaagagt gtgttagagg tacaacagta 27480 cttttaaaag aaccttgctc ttctggaaca tacgagggca attcaccatt tcatcctcta 27540 gctgataaca aatttgcact gacttgcttt agcactcaat ttgcttttgc ttgtcctgac 27600 ggcgtaaaac acgtctatca gttacgtgcc agatcagttt cacctaaact gttcatcaga 27660 caagaggaag ttcaagaact ttactctcca atttttctta ttgttgcggc aatagtgttt 27720 ataacacttt gcttcacact caaaagaaag acagaatgat tgaactttca ttaattgact 27780 tctatttgtg ctttttagcc tttctgctat tccttgtttt aattatgctt attatctttt 27840 ggttctcact tgaactgcaa gatcataatg aaacttgtca cgcctaaacg aacatgaaat 27900 ttcttgtttt cttaggaatc atcacaactg tagctgcatt tcaccaagaa tgtagtttac 27960 agtcatgtac tcaacatcaa ccatatgtag ttgatgaccc gtgtcctatt cacttctatt 28020 ctaaatggta tattagagta ggagctagaa aatcagcacc tttaattgaa ttgtgcgtgg 28080 atgaggctgg ttctaaatca cccattcagt acatcgatat cggtaattat acagtttcct 28140 gtttaccttt tacaattaat tgccaggaac ctaaattggg tagtcttgta gtgcgttgtt 28200 cgttctatga agacttttta gagtatcatg acgttcgtgt tgttttagat ttcatctaaa 28260 cgaacaaact aaaatgtctg ataatggacc ccaaaatcag cgaaatgcac cccgcattac 28320 gtttggtgga ccctcagatt caactggcag taaccagaat ggagaacgca gtggggcgcg 28380 atcaaaacaa cgtcggcccc aaggtttacc caataatact gcgtcttggt tcaccgctct 28440 cactcaacat ggcaaggaag accttaaatt ccctcgagga caaggcgttc caattaacac 28500 caatagcagt ccagatgacc aaattggcta ctaccgaaga gctaccagac gaattcgtgg 28560 tggtgacggt aaaatgaaag atctcagtcc aagatggtat ttctactacc taggaactgg 28620 gccagaagct ggacttccct atggtgctaa caaagacggc atcatatggg ttgcaactga 28680 gggagccttg aatacaccaa aagatcacat tggcacccgc aatcctgcta acaatgctgc 28740 aatcgtgcta caacttcctc aaggaacaac attgccaaaa ggcttctacg cagaagggag 28800 cagaggcggc agtcaagcct cttctcgttc ctcatcacgt agtcgcaaca gttcaagaaa 28860 ttcaactcca ggcagcagta ggggaacttc tcctgctaga atggctggca atggcggtga 28920 tgctgctctt gctttgctgc tgcttgacag attgaaccag cttgagagca aaatgtctgg 28980 taaaggccaa caacaacaag gccaaactgt cactaagaaa tctgctgctg aggcttctaa 29040 gaagcctcgg caaaaacgta ctgccactaa agcatacaat gtaacacaag ctttcggcag 29100 acgtggtcca gaacaaaccc aaggaaattt tggggaccag gaactaatca gacaaggaac 29160 tgattacaaa cattggccgc aaattgcaca atttgccccc agcgcttcag cgttcttcgg 29220 aatgtcgcgc attggcatgg aagtcacacc ttcgggaacg tggttgacct acacaggtgc 29280 catcaaattg gatgacaaag atccaaattt caaagatcaa gtcattttgc tgaataagca 29340 tattgacgca tacaaaacat tcccaccaac agagcctaaa aaggacaaaa agaagaaggc 29400 tgatgaaact caagccttac cgcagagaca gaagaaacag caaactgtga ctcttcttcc 29460 tgctgcagat ttggatgatt tctccaaaca attgcaacaa tccatgagca gtgctgactc 29520 aactcaggcc taaactcatg cagaccacac aaggcagatg ggctatataa acgttttcgc 29580 ttttccgttt acgatatata gtctactctt gtgcagaatg aattctcgta actacatagc 29640 acaagtagat gtagttaact ttaatctcac atagcaatct ttaatcagtg tgtaacatta 29700 gggaggactt gaaagagcca ccacattttc accgaggcca cgcggagtac gatcgagtgt 29760 acagtgaaca atgctaggga gagctgccta tatggaagag ccctaatgtg taaaattaat 29820 tttagtagtg ctatccccat gtgattttaa tagcttctta ggagaat 29867 <210> 10 <211> 7062 <212> PRT <213> SARS-CoV2 <220> <221> diferentes_características <222> (3606)..(3606) <223> Xaa puede ser cualquier aminoácido natural. <400> 10 Met Glu Ser Leu Val Pro Gly Phe Asn Glu Lys Thr Hes Val Gln Leu 1 5 10 15 Ser Leu Pro Val Leu Gln Val Arg Asp Val Leu Val Arg Gly Phe Gly 20 25 30 Asp Ser Val Glu Glu Val Leu Ser Glu Ala Arg Gln Hes Leu Lys Asp 35 40 45 Gly Thr Cys Gly Leu Val Glu Val Glu Lys Gly Val Leu Pro Gln Leu 50 55 60 Glu Gln Pro Tyr Val Phe Ile Lys Arg Ser Asp Ala Arg Thr Ala Pro 65 70 75 80 Hes Gly Hes Val Met Val Glu Leu Val Ala Glu Leu Glu Gly Ile Gln 85 90 95 Tyr Gly Arg Ser Gly Glu Thr Leu Gly Val Leu Val Pro Hes Val Gly 100 105 110 Glu Ile Pro Val Ala Tyr Arg Lys Val Leu Leu Arg Lys Asn Gly Asn 115 120 125 Lys Gly Ala Gly Gly Hes Ser Tyr Gly Ala Asp Leu Lys Ser Phe Asp 130 135 140 Leu Gly Asp Glu Leu Gly Thr Asp Pro Tyr Glu Asp Phe Gln Glu Asn 145 150 155 160 Trp Asn Thr Lys Hes Ser Ser Gly Val Thr Arg Glu Leu Met Arg Glu 165 170 175 Leu Asn Gly Gly Ala Tyr Thr Arg Tyr Val Asp Asn Asn Phe Cys Gly 180 185 190 Pro Asp Gly Tyr Pro Leu Glu Cys Ile Lys Asp Leu Leu Ala Arg Ala 195 200 205 Gly Lys Ala Ser Cys Thr Leu Ser Glu Gln Leu Asp Phe Ile Asp Thr 210 215 220 Lys Arg Gly Val Tyr Cys Cys Arg Glu Hes Glu Hes Glu Ile Ala Trp 225 230 235 240 Tyr Thr Glu Arg Ser Glu Lys Ser Tyr Glu Leu Gln Thr Pro Phe Glu 245 250 255 Ile Lys Leu Ala Lys Lys Phe Asp Thr Phe Asn Gly Glu Cys Pro Asn 260 265 270 Phe Val Phe Pro Leu Asn Ser Ile Ile Lys Thr Ile Gln Pro Arg Val 275 280 285 Glu Lys Lys Lys Leu Asp Gly Phe Met Gly Arg Ile Arg Ser Val Tyr 290 295 300 Pro Val Ala Ser Pro Asn Glu Cys Asn Gln Met Cys Leu Ser Thr Leu 305 310 315 320 Met Lys Cys Asp Hes Cys Gly Glu Thr Ser Trp Gln Thr Gly Asp Phe 325 330 335 Val Lys Ala Thr Cys Glu Phe Cys Gly Thr Glu Asn Leu Thr Lys Glu 340 345 350 Gly Ala Thr Thr Cys Gly Tyr Leu Pro Gln Asn Ala Val Val Lys Ile 355 360 365 Tyr Cys Pro Ala Cys Hes Asn Ser Glu Val Gly Pro Glu Hes Ser Leu 370 375 380 Ala Glu Tyr Hes Asn Glu Ser Gly Leu Lys Thr Ile Leu Arg Lys Gly 385 390 395 400 Gly Arg Thr Ile Ala Phe Gly Gly Cys Val Phe Ser Tyr Val Gly Cys 405 410 415 Hes Asn Lys Cys Ala Tyr Trp Val Pro Arg Ala Ser Ala Asn Ile Gly 420 425 430 Cys Asn Hes Thr Gly Val Val Gly Glu Gly Ser Glu Gly Leu Asn Asp 435 440 445 Asn Leu Leu Glu Ile Leu Gln Lys Glu Lys Val Asn Ile Asn Ile Val 450 455 460 Gly Asp Phe Lys Leu Asn Glu Glu Ile Ala Ile Ile Leu Ala Ser Phe 465 470 475 480 Ser Ala Ser Thr Ser Ala Phe Val Glu Thr Val Lys Gly Leu Asp Tyr 485 490 495 Lys Ala Phe Lys Gln Ile Val Glu Ser Cys Gly Asn Phe Lys Val Thr 500 505 510 Lys Gly Lys Ala Lys Lys Gly Ala Trp Asn Ile Gly Glu Gln Lys Ser 515 520 525 Ile Leu Ser Pro Leu Tyr Ala Phe Ala Ser Glu Ala Ala Arg Val Val 530 535 540 Arg Ser Ile Phe Ser Arg Thr Leu Glu Thr Ala Gln Asn Ser Val Arg 545 550 555 560 Val Leu Gln Lys Ala Ala Ile Thr Ile Leu Asp Gly Ile Ser Gln Tyr 565 570 575 Ser Leu Arg Leu Ile Asp Ala Met Met Phe Thr Ser Asp Leu Ala Thr 580 585 590 Asn Asn Leu Val Val Met Ala Tyr Ile Thr Gly Gly Val Val Gln Leu 595 600 605 Thr Ser Gln Trp Leu Thr Asn Ile Phe Gly Thr Val Tyr Glu Lys Leu 610 615 620 Lys Pro Val Leu Asp Trp Leu Glu Glu Lys Phe Lys Glu Gly Val Glu 625 630 635 640 Phe Leu Arg Asp Gly Trp Glu Ile Val Lys Phe Ile Ser Thr Cys Ala 645 650 655 Cys Glu Ile Val Gly Gly Gln Ile Val Thr Cys Ala Lys Glu Ile Lys 660 665 670 Glu Ser Val Gln Thr Phe Phe Lys Leu Val Asn Lys Phe Leu Ala Leu 675 680 685 Cys Ala Asp Ser Ile Ile Ile Gly Gly Ala Lys Leu Lys Ala Leu Asn 690 695 700 Leu Gly Glu Thr Phe Val Thr Hes Ser Lys Gly Leu Tyr Arg Lys Cys 705 710 715 720 Val Lys Ser Arg Glu Glu Thr Gly Leu Leu Met Pro Leu Lys Ala Pro 725 730 735 Lys Glu Ile Ile Phe Leu Glu Gly Glu Thr Leu Pro Thr Glu Val Leu 740 745 750 Thr Glu Glu Val Val Leu Lys Thr Gly Asp Leu Gln Pro Leu Glu Gln 755 760 765 Pro Thr Ser Glu Ala Val Glu Ala Pro Leu Val Gly Thr Pro Val Cys 770 775 780 Ile Asn Gly Leu Met Leu Leu Glu Ile Lys Asp Thr Glu Lys Tyr Cys 785 790 795 800 Ala Leu Ala Pro Asn Met Met Val Thr Asn Asn Thr Phe Thr Leu Lys 805 810 815 Gly Gly Ala Pro Thr Lys Val Thr Phe Gly Asp Asp Thr Val Ile Glu 820 825 830 Val Gln Gly Tyr Lys Ser Val Asn Ile Thr Phe Glu Leu Asp Glu Arg 835 840 845 Ile Asp Lys Val Leu Asn Glu Lys Cys Ser Ala Tyr Thr Val Glu Leu 850 855 860 Gly Thr Glu Val Asn Glu Phe Ala Cys Val Val Ala Asp Ala Val Ile 865 870 875 880 Lys Thr Leu Gln Pro Val Ser Glu Leu Leu Thr Pro Leu Gly Ile Asp 885 890 895 Leu Asp Glu Trp Ser Met Ala Thr Tyr Tyr Leu Phe Asp Glu Ser Gly 900 905 910 Glu Phe Lys Leu Ala Ser Hes Met Tyr Cys Ser Phe Tyr Pro Pro Asp 915 920 925 Glu Asp Glu Glu Glu Gly Asp Cys Glu Glu Glu Glu Phe Glu Pro Ser 930 935 940 Thr Gln Tyr Glu Tyr Gly Thr Glu Asp Asp Tyr Gln Gly Lys Pro Leu 945 950 955 960 Glu Phe Gly Ala Thr Ser Ala Ala Leu Gln Pro Glu Glu Glu Gln Glu 965 970 975 Glu Asp Trp Leu Asp Asp Asp Ser Gln Gln Thr Val Gly Gln Gln Asp 980 985 990 Gly Ser Glu Asp Asn Gln Thr Thr Thr Ile Gln Thr Ile Val Glu Val 995 1000 1005 Gln Pro Gln Leu Glu Met Glu Leu Thr Pro Val Val Gln Thr Ile 1010 1015 1020 Glu Val Asn Ser Phe Ser Gly Tyr Leu Lys Leu Thr Asp Asn Val 1025 1030 1035 Tyr Ile Lys Asn Ala Asp Ile Val Glu Glu Ala Lys Lys Val Lys 1040 1045 1050 Pro Thr Val Val Val Asn Ala Ala Asn Val Tyr Leu Lys Hes Gly 1055 1060 1065 Gly Gly Val Ala Gly Ala Leu Asn Lys Ala Thr Asn Asn Ala Met 1070 1075 1080 Gln Val Glu Ser Asp Asp Tyr Ile Ala Thr Asn Gly Pro Leu Lys 1085 1090 1095 Val Gly Gly Ser Cys Val Leu Ser Gly Hes Asn Leu Ala Lys Hes 1100 1105 1110 Cys Leu Hes Val Val Gly Pro Asn Val Asn Lys Gly Glu Asp Ile 1115 1120 1125 Gln Leu Leu Lys Ser Ala Tyr Glu Asn Phe Asn Gln Hes Glu Val 1130 1135 1140 Leu Leu Ala Pro Leu Leu Ser Ala Gly Ile Phe Gly Ala Asp Pro 1145 1150 1155 Ile Hes Ser Leu Arg Val Cys Val Asp Thr Val Arg Thr Asn Val 1160 1165 1170 Tyr Leu Ala Val Phe Asp Lys Asn Leu Tyr Asp Lys Leu Val Ser 1175 1180 1185 Ser Phe Leu Glu Met Lys Ser Glu Lys Gln Val Glu Gln Lys Ile 1190 1195 1200 Ala Glu Ile Pro Lys Glu Glu Val Lys Pro Phe Ile Thr Glu Ser 1205 1210 1215 Lys Pro Ser Val Glu Gln Arg Lys Gln Asp Asp Lys Lys Ile Lys 1220 1225 1230 Ala Cys Val Glu Glu Val Thr Thr Thr Leu Glu Glu Thr Lys Phe 1235 1240 1245 Leu Thr Glu Asn Leu Leu Leu Tyr Ile Asp Ile Asn Gly Asn Leu 1250 1255 1260 Hes Pro Asp Ser Ala Thr Leu Val Ser Asp Ile Asp Ile Thr Phe 1265 1270 1275 Leu Lys Lys Asp Ala Pro Tyr Ile Val Gly Asp Val Val Gln Glu 1280 1285 1290 Gly Val Leu Thr Ala Val Val Ile Pro Thr Lys Lys Ala Gly Gly 1295 1300 1305 Thr Thr Glu Met Leu Ala Lys Ala Leu Arg Lys Val Pro Thr Asp 1310 1315 1320 Asn Tyr Ile Thr Thr Tyr Pro Gly Gln Gly Leu Asn Gly Tyr Thr 1325 1330 1335 Val Glu Glu Ala Lys Thr Val Leu Lys Lys Cys Lys Ser Ala Phe 1340 1345 1350 Tyr Ile Leu Pro Ser Ile Ile Ser Asn Glu Lys Gln Glu Ile Leu 1355 1360 1365 Gly Thr Val Ser Trp Asn Leu Arg Glu Met Leu Ala Hes Ala Glu 1370 1375 1380 Glu Thr Arg Lys Leu Met Pro Val Cys Val Glu Thr Lys Ala Ile 1385 1390 1395 Val Ser Thr Ile Gln Arg Lys Tyr Lys Gly Ile Lys Ile Gln Glu 1400 1405 1410 Gly Val Val Asp Tyr Gly Ala Arg Phe Tyr Phe Tyr Thr Ser Lys 1415 1420 1425 Thr Thr Val Ala Ser Leu Ile Asn Thr Leu Asn Asp Leu Asn Glu 1430 1435 1440 Thr Leu Val Thr Met Pro Leu Gly Tyr Val Thr Hes Gly Leu Asn 1445 1450 1455 Leu Glu Glu Ala Ala Arg Tyr Met Arg Ser Leu Lys Val Pro Ala 1460 1465 1470 Thr Val Ser Val Ser Ser Pro Asp Ala Val Thr Ala Tyr Asn Gly 1475 1480 1485 Tyr Leu Thr Ser Ser Ser Lys Thr Pro Glu Glu Hes Phe Ile Glu 1490 1495 1500 Thr Ile Ser Leu Ala Gly Ser Tyr Lys Asp Trp Ser Tyr Ser Gly 1505 1510 1515 Gln Ser Thr Gln Leu Gly Ile Glu Phe Leu Lys Arg Gly Asp Lys 1520 1525 1530 Ser Val Tyr Tyr Thr Ser Asn Pro Thr Thr Phe Hes Leu Asp Gly 1535 1540 1545 Glu Val Ile Thr Phe Asp Asn Leu Lys Thr Leu Leu Ser Leu Arg 1550 1555 1560 Glu Val Arg Thr Ile Lys Val Phe Thr Thr Val Asp Asn Ile Asn 1565 1570 1575 Leu Hes Thr Gln Val Val Asp Met Ser Met Thr Tyr Gly Gln Gln 1580 1585 1590 Phe Gly Pro Thr Tyr Leu Asp Gly Ala Asp Val Thr Lys Ile Lys 1595 1600 1605 Pro Hes Asn Ser Hes Glu Gly Lys Thr Phe Tyr Val Leu Pro Asn 1610 1615 1620 Asp Asp Thr Leu Arg Val Glu Ala Phe Glu Tyr Tyr Hes Thr Thr 1625 1630 1635 Asp Pro Ser Phe Leu Gly Arg Tyr Met Ser Ala Leu Asn Hes Thr 1640 1645 1650 Lys Lys Trp Lys Tyr Pro Gln Val Asn Gly Leu Thr Ser Ile Lys 1655 1660 1665 Trp Ala Asp Asn Asn Cys Tyr Leu Ala Thr Ala Leu Leu Thr Leu 1670 1675 1680 Gln Gln Ile Glu Leu Lys Phe Asn Pro Pro Ala Leu Gln Asp Ala 1685 1690 1695 Tyr Tyr Arg Ala Arg Ala Gly Glu Ala Ala Asn Phe Cys Ala Leu 1700 1705 1710 Ile Leu Ala Tyr Cys Asn Lys Thr Val Gly Glu Leu Gly Asp Val 1715 1720 1725 Arg Glu Thr Met Ser Tyr Leu Phe Gln Hes Ala Asn Leu Asp Ser 1730 1735 1740 Cys Lys Arg Val Leu Asn Val Val Cys Lys Thr Cys Gly Gln Gln 1745 1750 1755 Gln Thr Thr Leu Lys Gly Val Glu Ala Val Met Tyr Met Gly Thr 1760 1765 1770 Leu Ser Tyr Glu Gln Phe Lys Lys Gly Val Gln Ile Pro Cys Thr 1775 1780 1785 Cys Gly Lys Gln Ala Thr Lys Tyr Leu Val Gln Gln Glu Ser Pro 1790 1795 1800 Phe Val Met Met Ser Ala Pro Pro Ala Gln Tyr Glu Leu Lys Hes 1805 1810 1815 Gly Thr Phe Thr Cys Ala Ser Glu Tyr Thr Gly Asn Tyr Gln Cys 1820 1825 1830 Gly Hes Tyr Lys Hes Ile Thr Ser Lys Glu Thr Leu Tyr Cys Ile 1835 1840 1845 Asp Gly Ala Leu Leu Thr Lys Ser Ser Glu Tyr Lys Gly Pro Ile 1850 1855 1860 Thr Asp Val Phe Tyr Lys Glu Asn Ser Tyr Thr Thr Thr Ile Lys 1865 1870 1875 Pro Val Thr Tyr Lys Leu Asp Gly Val Val Cys Thr Glu Ile Asp 1880 1885 1890 Pro Lys Leu Asp Asn Tyr Tyr Lys Lys Asp Asn Ser Tyr Phe Thr 1895 1900 1905 Glu Gln Pro Ile Asp Leu Val Pro Asn Gln Pro Tyr Pro Asn Ala 1910 1915 1920 Ser Phe Asp Asn Phe Lys Phe Val Cys Asp Asn Ile Lys Phe Ala 1925 1930 1935 Asp Asp Leu Asn Gln Leu Thr Gly Tyr Lys Lys Pro Ala Ser Arg 1940 1945 1950 Glu Leu Lys Val Thr Phe Phe Pro Asp Leu Asn Gly Asp Val Val 1955 1960 1965 Ala Ile Asp Tyr Lys Hes Tyr Thr Pro Ser Phe Lys Lys Gly Ala 1970 1975 1980 Lys Leu Leu Hes Lys Pro Ile Val Trp Hes Val Asn Asn Ala Thr 1985 1990 1995 Asn Lys Ala Thr Tyr Lys Pro Asn Thr Trp Cys Ile Arg Cys Leu 2000 2005 2010 Trp Ser Thr Lys Pro Val Glu Thr Ser Asn Ser Phe Asp Val Leu 2015 2020 2025 Lys Ser Glu Asp Ala Gln Gly Met Asp Asn Leu Ala Cys Glu Asp 2030 2035 2040 Leu Lys Pro Val Ser Glu Glu Val Val Glu Asn Pro Thr Ile Gln 2045 2050 2055 Lys Asp Val Leu Glu Cys Asn Val Lys Thr Thr Glu Val Val Gly 2060 2065 2070 Asp Ile Ile Leu Lys Pro Ala Asn Asn Ser Leu Lys Ile Thr Glu 2075 2080 2085 Glu Val Gly Hes Thr Asp Leu Met Ala Ala Tyr Val Asp Asn Ser 2090 2095 2100 Ser Leu Thr Ile Lys Lys Pro Asn Glu Leu Ser Arg Val Leu Gly 2105 2110 2115 Leu Lys Thr Leu Ala Thr Hes Gly Leu Ala Ala Val Asn Ser Val 2120 2125 2130 Pro Trp Asp Thr Ile Ala Asn Tyr Ala Lys Pro Phe Leu Asn Lys 2135 2140 2145 Val Val Ser Thr Thr Thr Asn Ile Val Thr Arg Cys Leu Asn Arg 2150 2155 2160 Val Cys Thr Asn Tyr Met Pro Tyr Phe Phe Thr Leu Leu Leu Gln 2165 2170 2175 Leu Cys Thr Phe Thr Arg Ser Thr Asn Ser Arg Ile Lys Ala Ser 2180 2185 2190 Met Pro Thr Thr Ile Ala Lys Asn Thr Val Lys Ser Val Gly Lys 2195 2200 2205 Phe Cys Leu Glu Ala Ser Phe Asn Tyr Leu Lys Ser Pro Asn Phe 2210 2215 2220 Ser Lys Leu Ile Asn Ile Ile Ile Trp Phe Leu Leu Leu Ser Val 2225 2230 2235 Cys Leu Gly Ser Leu Ile Tyr Ser Thr Ala Ala Leu Gly Val Leu 2240 2245 2250 Met Ser Asn Leu Gly Met Pro Ser Tyr Cys Thr Gly Tyr Arg Glu 2255 2260 2265 Gly Tyr Leu Asn Ser Thr Asn Val Thr Ile Ala Thr Tyr Cys Thr 2270 2275 2280 Gly Ser Ile Pro Cys Ser Val Cys Leu Ser Gly Leu Asp Ser Leu 2285 2290 2295 Asp Thr Tyr Pro Ser Leu Glu Thr Ile Gln Ile Thr Ile Ser Ser 2300 2305 2310 Phe Lys Trp Asp Leu Thr Ala Phe Gly Leu Val Ala Glu Trp Phe 2315 2320 2325 Leu Ala Tyr Ile Leu Phe Thr Arg Phe Phe Tyr Val Leu Gly Leu 2330 2335 2340 Ala Ala Ile Met Gln Leu Phe Phe Ser Tyr Phe Ala Val Hes Phe 2345 2350 2355 Ile Ser Asn Ser Trp Leu Met Trp Leu Ile Ile Asn Leu Val Gln 2360 2365 2370 Met Ala Pro Ile Ser Ala Met Val Arg Met Tyr Ile Phe Phe Ala 2375 2380 2385 Ser Phe Tyr Tyr Val Trp Lys Ser Tyr Val Hes Val Val Asp Gly 2390 2395 2400 Cys Asn Ser Ser Thr Cys Met Met Cys Tyr Lys Arg Asn Arg Ala 2405 2410 2415 Thr Arg Val Glu Cys Thr Thr Ile Val Asn Gly Val Arg Arg Ser 2420 2425 2430 Phe Tyr Val Tyr Ala Asn Gly Gly Lys Gly Phe Cys Lys Leu Hes 2435 2440 2445 Asn Trp Asn Cys Val Asn Cys Asp Thr Phe Cys Ala Gly Ser Thr 2450 2455 2460 Phe Ile Ser Asp Glu Val Ala Arg Asp Leu Ser Leu Gln Phe Lys 2465 2470 2475 Arg Pro Ile Asn Pro Thr Asp Gln Ser Ser Tyr Ile Val Asp Ser 2480 2485 2490 Val Thr Val Lys Asn Gly Ser Ile Hes Leu Tyr Phe Asp Lys Ala 2495 2500 2505 Gly Gln Lys Thr Tyr Glu Arg Hes Ser Leu Ser Hes Phe Val Asn 2510 2515 2520 Leu Asp Asn Leu Arg Ala Asn Asn Thr Lys Gly Ser Leu Pro Ile 2525 2530 2535 Asn Val Ile Val Phe Asp Gly Lys Ser Lys Cys Glu Glu Ser Ser 2540 2545 2550 Ala Lys Ser Ala Ser Val Tyr Tyr Ser Gln Leu Met Cys Gln Pro 2555 2560 2565 Ile Leu Leu Leu Asp Gln Ala Leu Val Ser Asp Val Gly Asp Ser 2570 2575 2580 Ala Glu Val Ala Val Lys Met Phe Asp Ala Tyr Val Asn Thr Phe 2585 2590 2595 Ser Ser Thr Phe Asn Val Pro Met Glu Lys Leu Lys Thr Leu Val 2600 2605 2610 Ala Thr Ala Glu Ala Glu Leu Ala Lys Asn Val Ser Leu Asp Asn 2615 2620 2625 Val Leu Ser Thr Phe Ile Ser Ala Ala Arg Gln Gly Phe Val Asp 2630 2635 2640 Ser Asp Val Glu Thr Lys Asp Val Val Glu Cys Leu Lys Leu Ser 2645 2650 2655 Hes Gln Ser Asp Ile Glu Val Thr Gly Asp Ser Cys Asn Asn Tyr 2660 2665 2670 Met Leu Thr Tyr Asn Lys Val Glu Asn Met Thr Pro Arg Asp Leu 2675 2680 2685 Gly Ala Cys Ile Asp Cys Ser Ala Arg Hes Ile Asn Ala Gln Val 2690 2695 2700 Ala Lys Ser Hes Asn Ile Ala Leu Ile Trp Asn Val Lys Asp Phe 2705 2710 2715 Met Ser Leu Ser Glu Gln Leu Arg Lys Gln Ile Arg Ser Ala Ala 2720 2725 2730 Lys Lys Asn Asn Leu Pro Phe Lys Leu Thr Cys Ala Thr Thr Arg 2735 2740 2745 Gln Val Val Asn Val Val Thr Thr Lys Ile Ala Leu Lys Gly Gly 2750 2755 2760 Lys Ile Val Asn Asn Trp Leu Lys Gln Leu Ile Lys Val Thr Leu 2765 2770 2775 Val Phe Leu Phe Val Ala Ala Ile Phe Tyr Leu Ile Thr Pro Val 2780 2785 2790 Hes Val Met Ser Lys Hes Thr Asp Phe Ser Ser Glu Ile Ile Gly 2795 2800 2805 Tyr Lys Ala Ile Asp Gly Gly Val Thr Arg Asp Ile Ala Ser Thr 2810 2815 2820 Asp Thr Cys Phe Ala Asn Lys Hes Ala Asp Phe Asp Thr Trp Phe 2825 2830 2835 Ser Gln Arg Gly Gly Ser Tyr Thr Asn Asp Lys Ala Cys Pro Leu 2840 2845 2850 Ile Ala Ala Val Ile Thr Arg Glu Val Gly Phe Val Val Pro Gly 2855 2860 2865 Leu Pro Gly Thr Ile Leu Arg Thr Thr Asn Gly Asp Phe Leu Hes 2870 2875 2880 Phe Leu Pro Arg Val Phe Ser Ala Val Gly Asn Ile Cys Tyr Thr 2885 2890 2895 Pro Ser Lys Leu Ile Glu Tyr Thr Asp Phe Ala Thr Ser Ala Cys 2900 2905 2910 Val Leu Ala Ala Glu Cys Thr Ile Phe Lys Asp Ala Ser Gly Lys 2915 2920 2925 Pro Val Pro Tyr Cys Tyr Asp Thr Asn Val Leu Glu Gly Ser Val 2930 2935 2940 Ala Tyr Glu Ser Leu Arg Pro Asp Thr Arg Tyr Val Leu Met Asp 2945 2950 2955 Gly Ser Ile Ile Gln Phe Pro Asn Thr Tyr Leu Glu Gly Ser Val 2960 2965 2970 Arg Val Val Thr Thr Phe Asp Ser Glu Tyr Cys Arg Hes Gly Thr 2975 2980 2985 Cys Glu Arg Ser Glu Ala Gly Val Cys Val Ser Thr Ser Gly Arg 2990 2995 3000 Trp Val Leu Asn Asn Asp Tyr Tyr Arg Ser Leu Pro Gly Val Phe 3005 3010 3015 Cys Gly Val Asp Ala Val Asn Leu Leu Thr Asn Met Phe Thr Pro 3020 3025 3030 Leu Ile Gln Pro Ile Gly Ala Leu Asp Ile Ser Ala Ser Ile Val 3035 3040 3045 Ala Gly Gly Ile Val Ala Ile Val Val Thr Cys Leu Ala Tyr Tyr 3050 3055 3060 Phe Met Arg Phe Arg Arg Ala Phe Gly Glu Tyr Ser Hes Val Val 3065 3070 3075 Ala Phe Asn Thr Leu Leu Phe Leu Met Ser Phe Thr Val Leu Cys 3080 3085 3090 Leu Thr Pro Val Tyr Ser Phe Leu Pro Gly Val Tyr Ser Val Ile 3095 3100 3105 Tyr Leu Tyr Leu Thr Phe Tyr Leu Thr Asn Asp Val Ser Phe Leu 3110 3115 3120 Ala Hes Ile Gln Trp Met Val Met Phe Thr Pro Leu Val Pro Phe 3125 3130 3135 Trp Ile Thr Ile Ala Tyr Ile Ile Cys Ile Ser Thr Lys Hes Phe 3140 3145 3150 Tyr Trp Phe Phe Ser Asn Tyr Leu Lys Arg Arg Val Val Phe Asn 3155 3160 3165 Gly Val Ser Phe Ser Thr Phe Glu Glu Ala Ala Leu Cys Thr Phe 3170 3175 3180 Leu Leu Asn Lys Glu Met Tyr Leu Lys Leu Arg Ser Asp Val Leu 3185 3190 3195 Leu Pro Leu Thr Gln Tyr Asn Arg Tyr Leu Ala Leu Tyr Asn Lys 3200 3205 3210 Tyr Lys Tyr Phe Ser Gly Ala Met Asp Thr Thr Ser Tyr Arg Glu 3215 3220 3225 Ala Ala Cys Cys Hes Leu Ala Lys Ala Leu Asn Asp Phe Ser Asn 3230 3235 3240 Ser Gly Ser Asp Val Leu Tyr Gln Pro Pro Gln Thr Ser Ile Thr 3245 3250 3255 Ser Ala Val Leu Gln Ser Gly Phe Arg Lys Met Ala Phe Pro Ser 3260 3265 3270 Gly Lys Val Glu Gly Cys Met Val Gln Val Thr Cys Gly Thr Thr 3275 3280 3285 Thr Leu Asn Gly Leu Trp Leu Asp Asp Val Val Tyr Cys Pro Arg 3290 3295 3300 Hes Val Ile Cys Thr Ser Glu Asp Met Leu Asn Pro Asn Tyr Glu 3305 3310 3315 Asp Leu Leu Ile Arg Lys Ser Asn Hes Asn Phe Leu Val Gln Ala 3320 3325 3330 Gly Asn Val Gln Leu Arg Val Ile Gly Hes Ser Met Gln Asn Cys 3335 3340 3345 Val Leu Lys Leu Lys Val Asp Thr Ala Asn Pro Lys Thr Pro Lys 3350 3355 3360 Tyr Lys Phe Val Arg Ile Gln Pro Gly Gln Thr Phe Ser Val Leu 3365 3370 3375 Ala Cys Tyr Asn Gly Ser Pro Ser Gly Val Tyr Gln Cys Ala Met 3380 3385 3390 Arg Pro Asn Phe Thr Ile Lys Gly Ser Phe Leu Asn Gly Ser Cys 3395 3400 3405 Gly Ser Val Gly Phe Asn Ile Asp Tyr Asp Cys Val Ser Phe Cys 3410 3415 3420 Tyr Met Hes Hes Met Glu Leu Pro Thr Gly Val Hes Ala Gly Thr 3425 3430 3435 Asp Leu Glu Gly Asn Phe Tyr Gly Pro Phe Val Asp Arg Gln Thr 3440 3445 3450 Ala Gln Ala Ala Gly Thr Asp Thr Thr Ile Thr Val Asn Val Leu 3455 3460 3465 Ala Trp Leu Tyr Ala Ala Val Ile Asn Gly Asp Arg Trp Phe Leu 3470 3475 3480 Asn Arg Phe Thr Thr Thr Leu Asn Asp Phe Asn Leu Val Ala Met 3485 3490 3495 Lys Tyr Asn Tyr Glu Pro Leu Thr Gln Asp Hes Val Asp Ile Leu 3500 3505 3510 Gly Pro Leu Ser Ala Gln Thr Gly Ile Ala Val Leu Asp Met Cys 3515 3520 3525 Ala Ser Leu Lys Glu Leu Leu Gln Asn Gly Met Asn Gly Arg Thr 3530 3535 3540 Ile Leu Gly Ser Ala Leu Leu Glu Asp Glu Phe Thr Pro Phe Asp 3545 3550 3555 Val Val Arg Gln Cys Ser Gly Val Thr Phe Gln Ser Ala Val Lys 3560 3565 3570 Arg Thr Ile Lys Gly Thr Hes Hes Trp Leu Leu Leu Thr Ile Leu 3575 3580 3585 Thr Ser Leu Leu Val Leu Val Gln Ser Thr Gln Trp Ser Leu Phe 3590 3595 3600 Phe Phe Xaa Tyr Glu Asn Ala Phe Leu Pro Phe Ala Met Gly Ile 3605 3610 3615 Ile Ala Met Ser Ala Phe Ala Met Met Phe Val Lys Hes Lys Hes 3620 3625 3630 Ala Phe Leu Cys Leu Phe Leu Leu Pro Ser Leu Ala Thr Val Ala 3635 3640 3645 Tyr Phe Asn Met Val Tyr Met Pro Ala Ser Trp Val Met Arg Ile 3650 3655 3660 Met Thr Trp Leu Asp Met Val Asp Thr Ser Leu Ser Gly Phe Lys 3665 3670 3675 Leu Lys Asp Cys Val Met Tyr Ala Ser Ala Val Val Leu Leu Ile 3680 3685 3690 Leu Met Thr Ala Arg Thr Val Tyr Asp Asp Gly Ala Arg Arg Val 3695 3700 3705 Trp Thr Leu Met Asn Val Leu Thr Leu Val Tyr Lys Val Tyr Tyr 3710 3715 3720 Gly Asn Ala Leu Asp Gln Ala Ile Ser Met Trp Ala Leu Ile Ile 3725 3730 3735 Ser Val Thr Ser Asn Tyr Ser Gly Val Val Thr Thr Val Met Phe 3740 3745 3750 Leu Ala Arg Gly Ile Val Phe Met Cys Val Glu Tyr Cys Pro Ile 3755 3760 3765 Phe Phe Ile Thr Gly Asn Thr Leu Gln Cys Ile Met Leu Val Tyr 3770 3775 3780 Cys Phe Leu Gly Tyr Phe Cys Thr Cys Tyr Phe Gly Leu Phe Cys 3785 3790 3795 Leu Leu Asn Arg Tyr Phe Arg Leu Thr Leu Gly Val Tyr Asp Tyr 3800 3805 3810 Leu Val Ser Thr Gln Glu Phe Arg Tyr Met Asn Ser Gln Gly Leu 3815 3820 3825 Leu Pro Pro Lys Asn Ser Ile Asp Ala Phe Lys Leu Asn Ile Lys 3830 3835 3840 Leu Leu Gly Val Gly Gly Lys Pro Cys Ile Lys Val Ala Thr Val 3845 3850 3855 Gln Ser Lys Met Ser Asp Val Lys Cys Thr Ser Val Val Leu Leu 3860 3865 3870 Ser Val Leu Gln Gln Leu Arg Val Glu Ser Ser Ser Lys Leu Trp 3875 3880 3885 Ala Gln Cys Val Gln Leu Hes Asn Asp Ile Leu Leu Ala Lys Asp 3890 3895 3900 Thr Thr Glu Ala Phe Glu Lys Met Val Ser Leu Leu Ser Val Leu 3905 3910 3915 Leu Ser Met Gln Gly Ala Val Asp Ile Asn Lys Leu Cys Glu Glu 3920 3925 3930 Met Leu Asp Asn Arg Ala Thr Leu Gln Ala Ile Ala Ser Glu Phe 3935 3940 3945 Ser Ser Leu Pro Ser Tyr Ala Ala Phe Ala Thr Ala Gln Glu Ala 3950 3955 3960 Tyr Glu Gln Ala Val Ala Asn Gly Asp Ser Glu Val Val Leu Lys 3965 3970 3975 Lys Leu Lys Lys Ser Leu Asn Val Ala Lys Ser Glu Phe Asp Arg 3980 3985 3990 Asp Ala Ala Met Gln Arg Lys Leu Glu Lys Met Ala Asp Gln Ala 3995 4000 4005 Met Thr Gln Met Tyr Lys Gln Ala Arg Ser Glu Asp Lys Arg Ala 4010 4015 4020 Lys Val Thr Ser Ala Met Gln Thr Met Leu Phe Thr Met Leu Arg 4025 4030 4035 Lys Leu Asp Asn Asp Ala Leu Asn Asn Ile Ile Asn Asn Ala Arg 4040 4045 4050 Asp Gly Cys Val Pro Leu Asn Ile Ile Pro Leu Thr Thr Ala Ala 4055 4060 4065 Lys Leu Met Val Val Ile Pro Asp Tyr Asn Thr Tyr Lys Asn Thr 4070 4075 4080 Cys Asp Gly Thr Thr Phe Thr Tyr Ala Ser Ala Leu Trp Glu Ile 4085 4090 4095 Gln Gln Val Val Asp Ala Asp Ser Lys Ile Val Gln Leu Ser Glu 4100 4105 4110 Ile Ser Met Asp Asn Ser Pro Asn Leu Ala Trp Pro Leu Ile Val 4115 4120 4125 Thr Ala Leu Arg Ala Asn Ser Ala Val Lys Leu Gln Asn Asn Glu 4130 4135 4140 Leu Ser Pro Val Ala Leu Arg Gln Met Ser Cys Ala Ala Gly Thr 4145 4150 4155 Thr Gln Thr Ala Cys Thr Asp Asp Asn Ala Leu Ala Tyr Tyr Asn 4160 4165 4170 Thr Thr Lys Gly Gly Arg Phe Val Leu Ala Leu Leu Ser Asp Leu 4175 4180 4185 Gln Asp Leu Lys Trp Ala Arg Phe Pro Lys Ser Asp Gly Thr Gly 4190 4195 4200 Thr Ile Tyr Thr Glu Leu Glu Pro Pro Cys Arg Phe Val Thr Asp 4205 4210 4215 Thr Pro Lys Gly Pro Lys Val Lys Tyr Leu Tyr Phe Ile Lys Gly 4220 4225 4230 Leu Asn Asn Leu Asn Arg Gly Met Val Leu Gly Ser Leu Ala Ala 4235 4240 4245 Thr Val Arg Leu Gln Ala Gly Asn Ala Thr Glu Val Pro Ala Asn 4250 4255 4260 Ser Thr Val Leu Ser Phe Cys Ala Phe Ala Val Asp Ala Ala Lys 4265 4270 4275 Ala Tyr Lys Asp Tyr Leu Ala Ser Gly Gly Gln Pro Ile Thr Asn 4280 4285 4290 Cys Val Lys Met Leu Cys Thr Hes Thr Gly Thr Gly Gln Ala Ile 4295 4300 4305 Thr Val Thr Pro Glu Ala Asn Met Asp Gln Glu Ser Phe Gly Gly 4310 4315 4320 Ala Ser Cys Cys Leu Tyr Cys Arg Cys Hes Ile Asp Hes Pro Asn 4325 4330 4335 Pro Lys Gly Phe Cys Asp Leu Lys Gly Lys Tyr Val Gln Ile Pro 4340 4345 4350 Thr Thr Cys Ala Asn Asp Pro Val Gly Phe Thr Leu Lys Asn Thr 4355 4360 4365 Val Cys Thr Val Cys Gly Met Trp Lys Gly Tyr Gly Cys Ser Cys 4370 4375 4380 Asp Gln Leu Arg Glu Pro Met Leu Gln Ser Ala Asp Ala Gln Ser 4385 4390 4395 Phe Leu Asn Arg Val Cys Gly Val Ser Ala Ala Arg Leu Thr Pro 4400 4405 4410 Cys Gly Thr Gly Thr Ser Thr Asp Val Val Tyr Arg Ala Phe Asp 4415 4420 4425 Ile Tyr Asn Asp Lys Val Ala Gly Phe Ala Lys Phe Leu Lys Thr 4430 4435 4440 Asn Cys Cys Arg Phe Gln Glu Lys Asp Glu Asp Asp Asn Leu Ile 4445 4450 4455 Asp Ser Tyr Phe Val Val Lys Arg Hes Thr Phe Ser Asn Tyr Gln 4460 4465 4470 Hes Glu Glu Thr Ile Tyr Asn Leu Leu Lys Asp Cys Pro Ala Val 4475 4480 4485 Ala Lys Hes Asp Phe Phe Lys Phe Arg Ile Asp Gly Asp Met Val 4490 4495 4500 Pro Hes Ile Ser Arg Gln Arg Leu Thr Lys Tyr Thr Met Ala Asp 4505 4510 4515 Leu Val Tyr Ala Leu Arg Hes Phe Asp Glu Gly Asn Cys Asp Thr 4520 4525 4530 Leu Lys Glu Ile Leu Val Thr Tyr Asn Cys Cys Asp Asp Asp Tyr 4535 4540 4545 Phe Asn Lys Lys Asp Trp Tyr Asp Phe Val Glu Asn Pro Asp Ile 4550 4555 4560 Leu Arg Val Tyr Ala Asn Leu Gly Glu Arg Val Arg Gln Ala Leu 4565 4570 4575 Leu Lys Thr Val Gln Phe Cys Asp Ala Met Arg Asn Ala Gly Ile 4580 4585 4590 Val Gly Val Leu Thr Leu Asp Asn Gln Asp Leu Asn Gly Asn Trp 4595 4600 4605 Tyr Asp Phe Gly Asp Phe Ile Gln Thr Thr Pro Gly Ser Gly Val 4610 4615 4620 Pro Val Val Asp Ser Tyr Tyr Ser Leu Leu Met Pro Ile Leu Thr 4625 4630 4635 Leu Thr Arg Ala Leu Thr Ala Glu Ser Hes Val Asp Thr Asp Leu 4640 4645 4650 Thr Lys Pro Tyr Ile Lys Trp Asp Leu Leu Lys Tyr Asp Phe Thr 4655 4660 4665 Glu Glu Arg Leu Lys Leu Phe Asp Arg Tyr Phe Lys Tyr Trp Asp 4670 4675 4680 Gln Thr Tyr Hes Pro Asn Cys Val Asn Cys Leu Asp Asp Arg Cys 4685 4690 4695 Ile Leu Hes Cys Ala Asn Phe Asn Val Leu Phe Ser Thr Val Phe 4700 4705 4710 Pro Pro Thr Ser Phe Gly Pro Leu Val Arg Lys Ile Phe Val Asp 4715 4720 4725 Gly Val Pro Phe Val Val Ser Thr Gly Tyr Hes Phe Arg Glu Leu 4730 4735 4740 Gly Val Val Hes Asn Gln Asp Val Asn Leu Hes Ser Ser Arg Leu 4745 4750 4755 Ser Phe Lys Glu Leu Leu Val Tyr Ala Ala Asp Pro Ala Met Hes 4760 4765 4770 Ala Ala Ser Gly Asn Leu Leu Leu Asp Lys Arg Thr Thr Cys Phe 4775 4780 4785 Ser Val Ala Ala Leu Thr Asn Asn Val Ala Phe Gln Thr Val Lys 4790 4795 4800 Pro Gly Asn Phe Asn Lys Asp Phe Tyr Asp Phe Ala Val Ser Lys 4805 4810 4815 Gly Phe Phe Lys Glu Gly Ser Ser Val Glu Leu Lys Hes Phe Phe 4820 4825 4830 Phe Ala Gln Asp Gly Asn Ala Ala Ile Ser Asp Tyr Asp Tyr Tyr 4835 4840 4845 Arg Tyr Asn Leu Pro Thr Met Cys Asp Ile Arg Gln Leu Leu Phe 4850 4855 4860 Val Val Glu Val Val Asp Lys Tyr Phe Asp Cys Tyr Asp Gly Gly 4865 4870 4875 Cys Ile Asn Ala Asn Gln Val Ile Val Asn Asn Leu Asp Lys Ser 4880 4885 4890 Ala Gly Phe Pro Phe Asn Lys Trp Gly Lys Ala Arg Leu Tyr Tyr 4895 4900 4905 Asp Ser Met Ser Tyr Glu Asp Gln Asp Ala Leu Phe Ala Tyr Thr 4910 4915 4920 Lys Arg Asn Val Ile Pro Thr Ile Thr Gln Met Asn Leu Lys Tyr 4925 4930 4935 Ala Ile Ser Ala Lys Asn Arg Ala Arg Thr Val Ala Gly Val Ser 4940 4945 4950 Ile Cys Ser Thr Met Thr Asn Arg Gln Phe Hes Gln Lys Leu Leu 4955 4960 4965 Lys Ser Ile Ala Ala Thr Arg Gly Ala Thr Val Val Ile Gly Thr 4970 4975 4980 Ser Lys Phe Tyr Gly Gly Trp Hes Asn Met Leu Lys Thr Val Tyr 4985 4990 4995 Ser Asp Val Glu Asn Pro Hes Leu Met Gly Trp Asp Tyr Pro Lys 5000 5005 5010 Cys Asp Arg Ala Met Pro Asn Met Leu Arg Ile Met Ala Ser Leu 5015 5020 5025 Val Leu Ala Arg Lys Hes Thr Thr Cys Cys Ser Leu Ser Hes Arg 5030 5035 5040 Phe Tyr Arg Leu Ala Asn Glu Cys Ala Gln Val Leu Ser Glu Met 5045 5050 5055 Val Met Cys Gly Gly Ser Leu Tyr Val Lys Pro Gly Gly Thr Ser 5060 5065 5070 Ser Gly Asp Ala Thr Thr Ala Tyr Ala Asn Ser Val Phe Asn Ile 5075 5080 5085 Cys Gln Ala Val Thr Ala Asn Val Asn Ala Leu Leu Ser Thr Asp 5090 5095 5100 Gly Asn Lys Ile Ala Asp Lys Tyr Val Arg Asn Leu Gln Hes Arg 5105 5110 5115 Leu Tyr Glu Cys Leu Tyr Arg Asn Arg Asp Val Asp Thr Asp Phe 5120 5125 5130 Val Asn Glu Phe Tyr Ala Tyr Leu Arg Lys Hes Phe Ser Met Met 5135 5140 5145 Ile Leu Ser Asp Asp Ala Val Val Cys Phe Asn Ser Thr Tyr Ala 5150 5155 5160 Ser Gln Gly Leu Val Ala Ser Ile Lys Asn Phe Lys Ser Val Leu 5165 5170 5175 Tyr Tyr Gln Asn Asn Val Phe Met Ser Glu Ala Lys Cys Trp Thr 5180 5185 5190 Glu Thr Asp Leu Thr Lys Gly Pro Hes Glu Phe Cys Ser Gln Hes 5195 5200 5205 Thr Met Leu Val Lys Gln Gly Asp Asp Tyr Val Tyr Leu Pro Tyr 5210 5215 5220 Pro Asp Pro Ser Arg Ile Leu Gly Ala Gly Cys Phe Val Asp Asp 5225 5230 5235 Ile Val Lys Thr Asp Gly Thr Leu Met Ile Glu Arg Phe Val Ser 5240 5245 5250 Leu Ala Ile Asp Ala Tyr Pro Leu Thr Lys Hes Pro Asn Gln Glu 5255 5260 5265 Tyr Ala Asp Val Phe Hes Leu Tyr Leu Gln Tyr Ile Arg Lys Leu 5270 5275 5280 Hes Asp Glu Leu Thr Gly Hes Met Leu Asp Met Tyr Ser Val Met 5285 5290 5295 Leu Thr Asn Asp Asn Thr Ser Arg Tyr Trp Glu Pro Glu Phe Tyr 5300 5305 5310 Glu Ala Met Tyr Thr Pro Hes Thr Val Leu Gln Ala Val Gly Ala 5315 5320 5325 Cys Val Leu Cys Asn Ser Gln Thr Ser Leu Arg Cys Gly Ala Cys 5330 5335 5340 Ile Arg Arg Pro Phe Leu Cys Cys Lys Cys Cys Tyr Asp Hes Val 5345 5350 5355 Ile Ser Thr Ser Hes Lys Leu Val Leu Ser Val Asn Pro Tyr Val 5360 5365 5370 Cys Asn Ala Pro Gly Cys Asp Val Thr Asp Val Thr Gln Leu Tyr 5375 5380 5385 Leu Gly Gly Met Ser Tyr Tyr Cys Lys Ser Hes Lys Pro Pro Ile 5390 5395 5400 Ser Phe Pro Leu Cys Ala Asn Gly Gln Val Phe Gly Leu Tyr Lys 5405 5410 5415 Asn Thr Cys Val Gly Ser Asp Asn Val Thr Asp Phe Asn Ala Ile 5420 5425 5430 Ala Thr Cys Asp Trp Thr Asn Ala Gly Asp Tyr Ile Leu Ala Asn 5435 5440 5445 Thr Cys Thr Glu Arg Leu Lys Leu Phe Ala Ala Glu Thr Leu Lys 5450 5455 5460 Ala Thr Glu Glu Thr Phe Lys Leu Ser Tyr Gly Ile Ala Thr Val 5465 5470 5475 Arg Glu Val Leu Ser Asp Arg Glu Leu Hes Leu Ser Trp Glu Val 5480 5485 5490 Gly Lys Pro Arg Pro Pro Leu Asn Arg Asn Tyr Val Phe Thr Gly 5495 5500 5505 Tyr Arg Val Thr Lys Asn Ser Lys Val Gln Ile Gly Glu Tyr Thr 5510 5515 5520 Phe Glu Lys Gly Asp Tyr Gly Asp Ala Val Val Tyr Arg Gly Thr 5525 5530 5535 Thr Thr Tyr Lys Leu Asn Val Gly Asp Tyr Phe Val Leu Thr Ser 5540 5545 5550 Hes Thr Val Met Pro Leu Ser Ala Pro Thr Leu Val Pro Gln Glu 5555 5560 5565 Hes Tyr Val Arg Ile Thr Gly Leu Tyr Pro Thr Leu Asn Ile Ser 5570 5575 5580 Asp Glu Phe Ser Ser Asn Val Ala Asn Tyr Gln Lys Val Gly Met 5585 5590 5595 Gln Lys Tyr Ser Thr Leu Gln Gly Pro Pro Gly Thr Gly Lys Ser 5600 5605 5610 Hes Phe Ala Ile Gly Leu Ala Leu Tyr Tyr Pro Ser Ala Arg Ile 5615 5620 5625 Val Tyr Thr Ala Cys Ser Hes Ala Ala Val Asp Ala Leu Cys Glu 5630 5635 5640 Lys Ala Leu Lys Tyr Leu Pro Ile Asp Lys Cys Ser Arg Ile Ile 5645 5650 5655 Pro Ala Arg Ala Arg Val Glu Cys Phe Asp Lys Phe Lys Val Asn 5660 5665 5670 Ser Thr Leu Glu Gln Tyr Val Phe Cys Thr Val Asn Ala Leu Pro 5675 5680 5685 Glu Thr Thr Ala Asp Ile Val Val Phe Asp Glu Ile Ser Met Ala 5690 5695 5700 Thr Asn Tyr Asp Leu Ser Val Val Asn Ala Arg Leu Arg Ala Lys 5705 5710 5715 Hes Tyr Val Tyr Ile Gly Asp Pro Ala Gln Leu Pro Ala Pro Arg 5720 5725 5730 Thr Leu Leu Thr Lys Gly Thr Leu Glu Pro Glu Tyr Phe Asn Ser 5735 5740 5745 Val Cys Arg Leu Met Lys Thr Ile Gly Pro Asp Met Phe Leu Gly 5750 5755 5760 Thr Cys Arg Arg Cys Pro Ala Glu Ile Val Asp Thr Val Ser Ala 5765 5770 5775 Leu Val Tyr Asp Asn Lys Leu Lys Ala Hes Lys Asp Lys Ser Ala 5780 5785 5790 Gln Cys Phe Lys Met Phe Tyr Lys Gly Val Ile Thr Hes Asp Val 5795 5800 5805 Ser Ser Ala Ile Asn Arg Pro Gln Ile Gly Val Val Arg Glu Phe 5810 5815 5820 Leu Thr Arg Asn Pro Ala Trp Arg Lys Ala Val Phe Ile Ser Pro 5825 5830 5835 Tyr Asn Ser Gln Asn Ala Val Ala Ser Lys Ile Leu Gly Leu Pro 5840 5845 5850 Thr Gln Thr Val Asp Ser Ser Gln Gly Ser Glu Tyr Asp Tyr Val 5855 5860 5865 Ile Phe Thr Gln Thr Thr Glu Thr Ala Hes Ser Cys Asn Val Asn 5870 5875 5880 Arg Phe Asn Val Ala Ile Thr Arg Ala Lys Val Gly Ile Leu Cys 5885 5890 5895 Ile Met Ser Asp Arg Asp Leu Tyr Asp Lys Leu Gln Phe Thr Ser 5900 5905 5910 Leu Glu Ile Pro Arg Arg Asn Val Ala Thr Leu Gln Ala Glu Asn 5915 5920 5925 Val Thr Gly Leu Phe Lys Asp Cys Ser Lys Val Ile Thr Gly Leu 5930 5935 5940 Hes Pro Thr Gln Ala Pro Thr Hes Leu Ser Val Asp Thr Lys Phe 5945 5950 5955 Lys Thr Glu Gly Leu Cys Val Asp Ile Pro Gly Ile Pro Lys Asp 5960 5965 5970 Met Thr Tyr Arg Arg Leu Ile Ser Met Met Gly Phe Lys Met Asn 5975 5980 5985 Tyr Gln Val Asn Gly Tyr Pro Asn Met Phe Ile Thr Arg Glu Glu 5990 5995 6000 Ala Ile Arg Hes Val Arg Ala Trp Ile Gly Phe Asp Val Glu Gly 6005 6010 6015 Cys Hes Ala Thr Arg Glu Ala Val Gly Thr Asn Leu Pro Leu Gln 6020 6025 6030 Leu Gly Phe Ser Thr Gly Val Asn Leu Val Ala Val Pro Thr Gly 6035 6040 6045 Tyr Val Asp Thr Pro Asn Asn Thr Asp Phe Ser Arg Val Ser Ala 6050 6055 6060 Lys Pro Pro Pro Gly Asp Gln Phe Lys Hes Leu Ile Pro Leu Met 6065 6070 6075 Tyr Lys Gly Leu Pro Trp Asn Val Val Arg Ile Lys Ile Val Gln 6080 6085 6090 Met Leu Ser Asp Thr Leu Lys Asn Leu Ser Asp Arg Val Val Phe 6095 6100 6105 Val Leu Trp Ala Hes Gly Phe Glu Leu Thr Ser Met Lys Tyr Phe 6110 6115 6120 Val Lys Ile Gly Pro Glu Arg Thr Cys Cys Leu Cys Asp Arg Arg 6125 6130 6135 Ala Thr Cys Phe Ser Thr Ala Ser Asp Thr Tyr Ala Cys Trp Hes 6140 6145 6150 Hes Ser Ile Gly Phe Asp Tyr Val Tyr Asn Pro Phe Met Ile Asp 6155 6160 6165 Val Gln Gln Trp Gly Phe Thr Gly Asn Leu Gln Ser Asn Hes Asp 6170 6175 6180 Leu Tyr Cys Gln Val Hes Gly Asn Ala Hes Val Ala Ser Cys Asp 6185 6190 6195 Ala Ile Met Thr Arg Cys Leu Ala Val Hes Glu Cys Phe Val Lys 6200 6205 6210 Arg Val Asp Trp Thr Ile Glu Tyr Pro Ile Ile Gly Asp Glu Leu 6215 6220 6225 Lys Ile Asn Ala Ala Cys Arg Lys Val Gln Hes Met Val Val Lys 6230 6235 6240 Ala Ala Leu Leu Ala Asp Lys Phe Pro Val Leu Hes Asp Ile Gly 6245 6250 6255 Asn Pro Lys Ala Ile Lys Cys Val Pro Gln Ala Asp Val Glu Trp 6260 6265 6270 Lys Phe Tyr Asp Ala Gln Pro Cys Ser Asp Lys Ala Tyr Lys Ile 6275 6280 6285 Glu Glu Leu Phe Tyr Ser Tyr Ala Thr Hes Ser Asp Lys Phe Thr 6290 6295 6300 Asp Gly Val Cys Leu Phe Trp Asn Cys Asn Val Asp Arg Tyr Pro 6305 6310 6315 Ala Asn Ser Ile Val Cys Arg Phe Asp Thr Arg Val Leu Ser Asn 6320 6325 6330 Leu Asn Leu Pro Gly Cys Asp Gly Gly Ser Leu Tyr Val Asn Lys 6335 6340 6345 Hes Ala Phe Hes Thr Pro Ala Phe Asp Lys Ser Ala Phe Val Asn 6350 6355 6360 Leu Lys Gln Leu Pro Phe Phe Tyr Tyr Ser Asp Ser Pro Cys Glu 6365 6370 6375 Ser Hes Gly Lys Gln Val Val Ser Asp Ile Asp Tyr Val Pro Leu 6380 6385 6390 Lys Ser Ala Thr Cys Ile Thr Arg Cys Asn Leu Gly Gly Ala Val 6395 6400 6405 Cys Arg Hes Hes Ala Asn Glu Tyr Arg Leu Tyr Leu Asp Ala Tyr 6410 6415 6420 Asn Met Met Ile Ser Ala Gly Phe Ser Leu Trp Val Tyr Lys Gln 6425 6430 6435 Phe Asp Thr Tyr Asn Leu Trp Asn Thr Phe Thr Arg Leu Gln Ser 6440 6445 6450 Leu Glu Asn Val Ala Phe Asn Val Val Asn Lys Gly Hes Phe Asp 6455 6460 6465 Gly Gln Gln Gly Glu Val Pro Val Ser Ile Ile Asn Asn Thr Val 6470 6475 6480 Tyr Thr Lys Val Asp Gly Val Asp Val Glu Leu Phe Glu Asn Lys 6485 6490 6495 Thr Thr Leu Pro Val Asn Val Ala Phe Glu Leu Trp Ala Lys Arg 6500 6505 6510 Asn Ile Lys Pro Val Pro Glu Val Lys Ile Leu Asn Asn Leu Gly 6515 6520 6525 Val Asp Ile Ala Ala Asn Thr Val Ile Trp Asp Tyr Lys Arg Asp 6530 6535 6540 Ala Pro Ala Hes Ile Ser Thr Ile Gly Val Cys Ser Met Thr Asp 6545 6550 6555 Ile Ala Lys Lys Pro Thr Glu Thr Ile Cys Ala Pro Leu Thr Val 6560 6565 6570 Phe Phe Asp Gly Arg Val Asp Gly Gln Val Asp Leu Phe Arg Asn 6575 6580 6585 Ala Arg Asn Gly Val Leu Ile Thr Glu Gly Ser Val Lys Gly Leu 6590 6595 6600 Gln Pro Ser Val Gly Pro Lys Gln Ala Ser Leu Asn Gly Val Thr 6605 6610 6615 Leu Ile Gly Glu Ala Val Lys Thr Gln Phe Asn Tyr Tyr Lys Lys 6620 6625 6630 Val Asp Gly Val Val Gln Gln Leu Pro Glu Thr Tyr Phe Thr Gln 6635 6640 6645 Ser Arg Asn Leu Gln Glu Phe Lys Pro Arg Ser Gln Met Glu Ile 6650 6655 6660 Asp Phe Leu Glu Leu Ala Met Asp Glu Phe Ile Glu Arg Tyr Lys 6665 6670 6675 Leu Glu Gly Tyr Ala Phe Glu Hes Ile Val Tyr Gly Asp Phe Ser 6680 6685 6690 Hes Ser Gln Leu Gly Gly Leu Hes Leu Leu Ile Gly Leu Ala Lys 6695 6700 6705 Arg Phe Lys Glu Ser Pro Phe Glu Leu Glu Asp Phe Ile Pro Met 6710 6715 6720 Asp Ser Thr Val Lys Asn Tyr Phe Ile Thr Asp Ala Gln Thr Gly 6725 6730 6735 Ser Ser Lys Cys Val Cys Ser Val Ile Asp Leu Leu Leu Asp Asp 6740 6745 6750 Phe Val Glu Ile Ile Lys Ser Gln Asp Leu Ser Val Val Ser Lys 6755 6760 6765 Val Val Lys Val Thr Ile Asp Tyr Thr Glu Ile Ser Phe Met Leu 6770 6775 6780 Trp Cys Lys Asp Gly Hes Val Glu Thr Phe Tyr Pro Lys Leu Gln 6785 6790 6795 Ser Ser Gln Ala Trp Gln Pro Gly Val Ala Met Pro Asn Leu Tyr 6800 6805 6810 Lys Met Gln Arg Met Leu Leu Glu Lys Cys Asp Leu Gln Asn Tyr 6815 6820 6825 Gly Asp Ser Ala Thr Leu Pro Lys Gly Ile Met Met Asn Val Ala 6830 6835 6840 Lys Tyr Thr Gln Leu Cys Gln Tyr Leu Asn Thr Leu Thr Leu Ala 6845 6850 6855 Val Pro Tyr Asn Met Arg Val Ile Hes Phe Gly Ala Gly Ser Asp 6860 6865 6870 Lys Gly Val Ala Pro Gly Thr Ala Val Leu Arg Gln Trp Leu Pro 6875 6880 6885 Thr Gly Thr Leu Leu Val Asp Ser Asp Leu Asn Asp Phe Val Ser 6890 6895 6900 Asp Ala Asp Ser Thr Leu Ile Gly Asp Cys Ala Thr Val Hes Thr 6905 6910 6915 Ala Asn Lys Trp Asp Leu Ile Ile Ser Asp Met Tyr Asp Pro Lys 6920 6925 6930 Thr Lys Asn Val Thr Lys Glu Asn Asp Ser Lys Glu Gly Phe Phe 6935 6940 6945 Thr Tyr Ile Cys Gly Phe Ile Gln Gln Lys Leu Ala Leu Gly Gly 6950 6955 6960 Ser Val Ala Ile Lys Ile Thr Glu Hes Ser Trp Asn Ala Asp Leu 6965 6970 6975 Tyr Lys Leu Met Gly Hes Phe Ala Trp Trp Thr Ala Phe Val Thr 6980 6985 6990 Asn Val Asn Ala Ser Ser Ser Glu Ala Phe Leu Ile Gly Cys Asn 6995 7000 7005 Tyr Leu Gly Lys Pro Arg Glu Gln Ile Asp Gly Tyr Val Met Hes 7010 7015 7020 Ala Asn Tyr Ile Phe Trp Arg Asn Thr Asn Pro Ile Gln Leu Ser 7025 7030 7035 Ser Tyr Ser Leu Phe Asp Met Ser Lys Phe Pro Leu Lys Leu Arg 7040 7045 7050 Gly Thr Ala Val Met Ser Leu Lys Glu 7055 7060 <210> 11 <211> 1273 <212> PRT <213> SARS-CoV2 <400> 11 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ser Gln Cys Val 1 5 10 15 Asn Leu Thr Thr Arg Thr Gln Leu Pro Pro Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Hes Val Ser Gly Thr Asn Gly Thr Lys Arg Phe Asp 65 70 75 80 Asn Pro Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu 85 90 95 Lys Ser Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser 100 105 110 Lys Thr Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile 115 120 125 Lys Val Cys Glu Phe Gln Phe Cys Asn Asp Pro Phe Leu Gly Val Tyr 130 135 140 Tyr Hes Lys Asn Asn Lys Ser Trp Met Glu Ser Glu Phe Arg Val Tyr 145 150 155 160 Ser Ser Ala Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu 165 170 175 Met Asp Leu Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Arg Glu Phe 180 185 190 Val Phe Lys Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr 195 200 205 Pro Ile Asn Leu Val Arg Asp Leu Pro Gln Gly Phe Ser Ala Leu Glu 210 215 220 Pro Leu Val Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Thr 225 230 235 240 Leu Leu Ala Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser 245 250 255 Gly Trp Thr Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro 260 265 270 Arg Thr Phe Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala 275 280 285 Val Asp Cys Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys 290 295 300 Ser Phe Thr Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Val 305 310 315 320 Gln Pro Thr Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys 325 330 335 Pro Phe Gly Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala 340 345 350 Trp Asn Arg Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Val Leu 355 360 365 Tyr Asn Ser Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro 370 375 380 Thr Lys Leu Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe 385 390 395 400 Val Ile Arg Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly 405 410 415 Lys Ile Ala Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys 420 425 430 Val Ile Ala Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn 435 440 445 Tyr Asn Tyr Leu Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe 450 455 460 Glu Arg Asp Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys 465 470 475 480 Asn Gly Val Glu Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly 485 490 495 Phe Gln Pro Thr Asn Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val 500 505 510 Leu Ser Phe Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys 515 520 525 Lys Ser Thr Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn 530 535 540 Gly Leu Thr Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu 545 550 555 560 Pro Phe Gln Gln Phe Gly Arg Asp Ile Ala Asp Thr Thr Asp Ala Val 565 570 575 Arg Asp Pro Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe 580 585 590 Gly Gly Val Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val 595 600 605 Ala Val Leu Tyr Gln Asp Val Asn Cys Thr Glu Val Pro Val Ala Ile 610 615 620 Hes Ala Asp Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser 625 630 635 640 Asn Val Phe Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Hes Val 645 650 655 Asn Asn Ser Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala 660 665 670 Ser Tyr Gln Thr Gln Thr Asn Ser Pro Arg Arg Ala Arg Ser Val Ala 675 680 685 Ser Gln Ser Ile Ile Ala Tyr Thr Met Ser Leu Gly Ala Glu Asn Ser 690 695 700 Val Ala Tyr Ser Asn Asn Ser Ile Ala Ile Pro Thr Asn Phe Thr Ile 705 710 715 720 Ser Val Thr Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val 725 730 735 Asp Cys Thr Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu 740 745 750 Leu Leu Gln Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr 755 760 765 Gly Ile Ala Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln 770 775 780 Val Lys Gln Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe 785 790 795 800 Asn Phe Ser Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser 805 810 815 Phe Ile Glu Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly 820 825 830 Phe Ile Lys Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp 835 840 845 Leu Ile Cys Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu 850 855 860 Leu Thr Asp Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly 865 870 875 880 Thr Ile Thr Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile 885 890 895 Pro Phe Ala Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr 900 905 910 Gln Asn Val Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn 915 920 925 Ser Ala Ile Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala 930 935 940 Leu Gly Lys Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn 945 950 955 960 Thr Leu Val Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val 965 970 975 Leu Asn Asp Ile Leu Ser Arg Leu Asp Lys Val Glu Ala Glu Val Gln 980 985 990 Ile Asp Arg Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val 995 1000 1005 Thr Gln Gln Leu Ile Arg Ala Ala Glu Ile Arg Ala Ser Ala Asn 1010 1015 1020 Leu Ala Ala Thr Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys 1025 1030 1035 Arg Val Asp Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro 1040 1045 1050 Gln Ser Ala Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val 1055 1060 1065 Pro Ala Gln Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes 1070 1075 1080 Asp Gly Lys Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn 1085 1090 1095 Gly Thr Hes Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln 1100 1105 1110 Ile Ile Thr Thr Asp Asn Thr Phe Val Ser Gly Asn Cys Asp Val 1115 1120 1125 Val Ile Gly Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro 1130 1135 1140 Glu Leu Asp Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn 1145 1150 1155 Hes Thr Ser Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn 1160 1165 1170 Ala Ser Val Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu 1175 1180 1185 Val Ala Lys Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu 1190 1195 1200 Gly Lys Tyr Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu 1205 1210 1215 Gly Phe Ile Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met 1220 1225 1230 Leu Cys Cys Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys 1235 1240 1245 Ser Cys Gly Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro 1250 1255 1260 Val Leu Lys Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 12 <211> 29874 <212> ADN <213> SARS-CoV2 <400> 12 attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct 60 gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact 120 cacgcagtat aattaataac taattactgt cgttgacagg acacgagtaa ctcgtctatc 180 ttctgcaggc tgcttacggt ttcgtccgtg ttgcagccga tcatcagcac atctaggttt 240 cgtccgggtg tgaccgaaag gtaagatgga gagccttgtc cctggtttca acgagaaaac 300 acacgtccaa ctcagtttgc ctgttttaca ggttcgcgac gtgctcgtac gtggctttgg 360 agactccgtg gaggaggtct tatcagaggc acgtcaacat cttaaagatg gcacttgtgg 420 cttagtagaa gttgaaaaag gcgttttgcc tcaacttgaa cagccctatg tgttcatcaa 480 acgttcggat gctcgaactg cacctcatgg tcatgttatg gttgagctgg tagcagaact 540 cgaaggcatt cagtacggtc gtagtggtga gacacttggt gtccttgtcc ctcatgtggg 600 cgaaatacca gtggcttacc gcaaggttct tcttcgtaag aacggtaata aaggagctgg 660 tggccatagt tacggcgccg atctaaagtc atttgactta ggcgacgagc ttggcactga 720 tccttatgaa gattttcaag aaaactggaa cactaaacat agcagtggtg ttacccgtga 780 actcatgcgt gagcttaacg gaggggcata cactcgctat gtcgataaca acttctgtgg 840 ccctgatggc taccctcttg agtgcattaa agaccttcta gcacgtgctg gtaaagcttc 900 atgcactttg tccgaacaac tggactttat tgacactaag aggggtgtat actgctgccg 960 tgaacatgag catgaaattg cttggtacac ggaacgttct gaaaagagct atgaattgca 1020 gacacctttt gaaattaaat tggcaaagaa atttgacacc ttcaatgggg aatgtccaaa 1080 ttttgtattt cccttaaatt ccataatcaa gactattcaa ccaagggttg aaaagaaaaa 1140 gcttgatggc tttatgggta gaattcgatc tgtctatcca gttgcgtcac caaatgaatg 1200 caaccaaatg tgcctttcaa ctctcatgaa gtgtgatcat tgtggtgaaa cttcatggca 1260 gacgggcgat tttgttaaag ccacttgcga attttgtggc actgagaatt tgactaaaga 1320 aggtgccact acttgtggtt acttacccca aaatgctgtt gttaaaattt attgtccagc 1380 atgtcacaat tcagaagtag gacctgagca tagtcttgcc gaataccata atgaatctgg 1440 cttgaaaacc attcttcgta agggtggtcg cactattgcc tttggaggct gtgtgttctc 1500 ttatgttggt tgccataaca agtgtgccta ttgggttcca cgtgctagcg ctaacatagg 1560 ttgtaaccat acaggtgttg ttggagaagg ttccgaaggt cttaatgaca accttcttga 1620 aatactccaa aaagagaaag tcaacatcaa tattgttggt gactttaaac ttaatgaaga 1680 gatcgccatt attttggcat ctttttctgc ttccacaagt gcttttgtgg aaactgtgaa 1740 aggtttggat tataaagcat tcaaacaaat tgttgaatcc tgtggtaatt ttaaagttac 1800 aaaaggaaaa gctaaaaaag gtgcctggaa tattggtgaa cagaaatcaa tactgagtcc 1860 tctttatgca tttgcatcag aggctgctcg tgttgtacga tcaattttct cccgcactct 1920 tgaaactgct caaaattctg tgcgtgtttt acagaaggcc gctataacaa tactagatgg 1980 aatttcacag tattcactga gactcattga tgctatgatg ttcacatctg atttggctac 2040 taacaatcta gttgtaatgg cctacattac aggtggtgtt gttcagttga cttcgcagtg 2100 gctaactaac atctttggca ctgtttatga aaaactcaaa cccgtccttg attggcttga 2160 agagaagttt aaggaaggtg tagagtttct tagagacggt tgggaaattg ttaaatttat 2220 ctcaacctgt gcttgtgaaa ttgtcggtgg acaaattgtc acctgtgcaa aggaaattaa 2280 ggagagtgtt cagacattct ttaagcttgt aaataaattt ttggctttgt gtgctgactc 2340 tatcattatt ggtggagcta aacttaaagc cttgaattta ggtgaaacat ttgtcacgca 2400 ctcaaaggga ttgtacagaa agtgtgttaa atccagagaa gaaactggcc tactcatgcc 2460 tctaaaagcc ccaaaagaaa ttatcttctt agagggagaa acacttccca cagaagtgtt 2520 aacagaggaa gttgtcttga aaactggtga tttacaacca ttagaacaac ctactagtga 2580 agctgttgaa gctccattgg ttggtacacc agtttgtatt aacgggctta tgttgctcga 2640 aatcaaagac acagaaaagt actgtgccct tgcacctaat atgatggtaa caaacaatac 2700 cttcacactc aaaggcggtg caccaacaaa ggttactttt ggtgatgaca ctgtgataga 2760 agtgcaaggt tacaagagtg tgaatatcac ttttgaactt gatgaaagga ttgataaagt 2820 acttaatgag aagtgctctg cctatacagt tgaactcggt acagaagtaa atgagttcgc 2880 ctgtgttgtg gcagatgctg tcataaaaac tttgcaacca gtatctgaat tacttacacc 2940 actgggcatt gatttagatg agtggagtat ggctacatac tacttatttg atgagtctgg 3000 tgagtttaaa ttggcttcac atatgtattg ttctttctac cctccagatg aggatgaaga 3060 agaaggtgat tgtgaagaag aagagtttga gccatcaact caatatgagt atggtactga 3120 agatgattac caaggtaaac ctttggaatt tggtgccact tctgctgctc ttcaacctga 3180 agaagagcaa gaagaagatt ggttagatga tgatagtcaa caaactgttg gtcaacaaga 3240 cggcagtgag gacaatcaga caactactat tcaaacaatt gttgaggttc aacctcaatt 3300 agagatggaa cttacaccag ttgttcagac tattgaagtg aatagtttta gtggttattt 3360 aaaacttact gacaatgtat acattaaaaa tgcagacatt gtggaagaag ctaaaaaggt 3420 aaaaccaaca gtggttgtta atgcagccaa tgtttacctt aaacatggag gaggtgttgc 3480 aggagcctta aataaggcta ctaacaatgc catgcaagtt gaatctgatg attacatagc 3540 tactaatgga ccacttaaag tgggtggtag ttgtgtttta agcggacaca atcttgctaa 3600 acactgtctt catgttgtcg gcccaaatgt taacaaaggt gaagacattc aacttcttaa 3660 gagtgcttat gaaaatttta atcagcacga agttctactt gcaccattat tatcagctgg 3720 tatttttggt gctgacccta tacattcttt aagagtttgt gtagatactg ttcgcacaaa 3780 tgtctactta gctgtctttg ataaaaatct ctatgacaaa cttgtttcaa gctttttgga 3840 aatgaagagt gaaaagcaag ttgaacaaaa gatcgctgag attcctaaag aggaagttaa 3900 gccatttata actgaaagta aaccttcagt tgaacagaga aaacaagatg ataagaaaat 3960 caaagcttgt gttgaagaag ttacaacaac tctggaagaa actaagttcc tcacagaaaa 4020 cttgttactt tatattgaca ttaatggcaa tcttcatcca gattctgcca ctcttgttag 4080 tgacattgac atcactttct taaagaaaga tgctccatat atagtgggtg atgttgttca 4140 agagggtgtt ttaactgctg tggttatacc tactaaaaag gctggtggca ctactgaaat 4200 gctagcgaaa gctttgagaa aagtgccaac agacaattat ataaccactt acccgggtca 4260 gggtttaaat ggttacactg tagaggaggc aaagacagtg cttaaaaagt gtaaaagtgc 4320 cttttacatt ctaccatcta ttatctctaa tgagaagcaa gaaattcttg gaactgtttc 4380 ttggaatttg cgagaaatgc ttgcacatgc agaagaaaca cgcaaattaa tgcctgtctg 4440 tgtggaaact aaagccatag tttcaactat acagcgtaaa tataagggta ttaaaataca 4500 agagggtgtg gttgattatg gtgctagatt ttacttttac accagtaaaa caactgtagc 4560 gtcacttatc aacacactta acgatctaaa tgaaactctt gttacaatgc cacttggcta 4620 tgtaacacat ggcttaaatt tggaagaagc tgctcggtat atgagatctc tcaaagtgcc 4680 agctacagtt tctgtttctt cacctgatgc tgttacagcg tataatggtt atcttacttc 4740 ttcttctaaa acacctgaag aacattttat tgaaaccatc tcacttgctg gttcctataa 4800 agattggtcc tattctggac aatctacaca actaggtata gaatttctta agagaggtga 4860 taaaagtgta tattacacta gtaatcctac cacattccac ctagatggtg aagttatcac 4920 ctttgacaat cttaagacac ttctttcttt gagagaagtg aggactatta aggtgtttac 4980 aacagtagac aacattaacc tccacacgca agttgtggac atgtcaatga catatggaca 5040 acagtttggt ccaacttatt tggatggagc tgatgttact aaaataaaac ctcataattc 5100 acatgaaggt aaaacatttt atgttttacc taatgatgac actctacgtg ttgaggcttt 5160 tgagtactac cacacaactg atcctagttt tctgggtagg tacatgtcag cattaaatca 5220 cactaaaaag tggaaatacc cacaagttaa tggtttaact tctattaaat gggcagataa 5280 caactgttat cttgccactg cattgttaac actccaacaa atagagttga agtttaatcc 5340 acctgctcta caagatgctt attacagagc aagggctggt gaagctgcta acttttgtgc 5400 acttatctta gcctactgta ataagacagt aggtgagtta ggtgatgtta gagaaacaat 5460 gagttacttg tttcaacatg ccaatttaga ttcttgcaaa agagtcttga acgtggtgtg 5520 taaaacttgt ggacaacagc agacaaccct taagggtgta gaagctgtta tgtacatggg 5580 cacactttct tatgaacaat ttaagaaagg tgttcagata ccttgtacgt gtggtaaaca 5640 agctacaaaa tatctagtac aacaggagtc accttttgtt atgatgtcag caccacctgc 5700 tcagtatgaa cttaagcatg gtacatttac ttgtgctagt gagtacactg gtaattacca 5760 gtgtggtcac tataaacata taacttctaa agaaactttg tattgcatag acggtgcttt 5820 acttacaaag tcctcagaat acaaaggtcc tattacggat gttttctaca aagaaaacag 5880 ttacacaaca accataaaac cagttactta taaattggat ggtgttgttt gtacagaaat 5940 tgaccctaag ttggacaatt attataagaa agacaattct tatttcacag agcaaccaat 6000 tgatcttgta ccaaaccaac catatccaaa cgcaagcttc gataatttta agtttgtatg 6060 tgataatatc aaatttgctg atgatttaaa ccagttaact ggttataaga aacctgcttc 6120 aagagagctt aaagttacat ttttccctga cttaaatggt gatgtggtgg ctattgatta 6180 taaacactac acaccctctt ttaagaaagg agctaaattg ttacataaac ctattgtttg 6240 gcatgttaac aatgcaacta ataaagccac gtataaacca aatacctggt gtatacgttg 6300 tctttggagc acaaaaccag ttgaaacatc aaattcgttt gatgtactga agtcagagga 6360 cgcgcaggga atggataatc ttgcctgcga agatctaaaa ccagtctctg aagaagtagt 6420 ggaaaatcct accatacaga aagacgttct tgagtgtaat gtgaaaacta ccgaagttgt 6480 aggagacatt atacttaaac cagcaaataa tagtttaaaa attacagaag aggttggcca 6540 cacagatcta atggctgctt atgtagacaa ttctagtctt actattaaga aacctaatga 6600 attatctaga gtattaggtt tgaaaaccct tgctactcat ggtttagctg ctgttaatag 6660 tgtcccttgg gatactatag ctaattatgc taagcctttt cttaacaaag ttgttagtac 6720 aactactaac atagttacac ggtgtttaaa ccgtgtttgt actaattata tgccttattt 6780 ctttacttta ttgctacaat tgtgtacttt tactagaagt acaaattcta gaattaaagc 6840 atctatgccg actactatag caaagaatac tgttaagagt gtcggtaaat tttgtctaga 6900 ggcttcattt aattatttga agtcacctaa tttttctaaa ctgataaata ttataatttg 6960 gtttttacta ttaagtgttt gcctaggttc tttaatctac tcaaccgctg ctttaggtgt 7020 tttaatgtct aatttaggca tgccttctta ctgtactggt tacagagaag gctatttgaa 7080 ctctactaat gtcactattg caacctactg tactggttct ataccttgta gtgtttgtct 7140 tagtggttta gattctttag acacctatcc ttctttagaa actatacaaa ttaccatttc 7200 atcttttaaa tgggatttaa ctgcttttgg cttagttgca gagtggtttt tggcatatat 7260 tcttttcact aggtttttct atgtacttgg attggctgca atcatgcaat tgtttttcag 7320 ctattttgca gtacatttta ttagtaattc ttggcttatg tggttaataa ttaatcttgt 7380 acaaatggcc ccgatttcag ctatggttag aatgtacatc ttctttgcat cattttatta 7440 tgtatggaaa agttatgtgc atgttgtaga cggttgtaat tcatcaactt gtatgatgtg 7500 ttacaaacgt aatagagcaa caagagtcga atgtacaact attgttaatg gtgttagaag 7560 gtccttttat gtctatgcta atggaggtaa aggcttttgc aaactacaca attggaattg 7620 tgttaattgt gatacattct gtgctggtag tacatttatt agtgatgaag ttgcgagaga 7680 cttgtcacta cagtttaaaa gaccaataaa tcctactgac cagtcttctt acatcgttga 7740 tagtgttaca gtgaagaatg gttccatcca tctttacttt gataaagctg gtcaaaagac 7800 ttatgaaaga cattctctct ctcattttgt taacttagac aacctgagag ctaataacac 7860 taaaggttca ttgcctatta atgttatagt ttttgatggt aaatcaaaat gtgaagaatc 7920 atctgcaaaa tcagcgtctg tttactacag tcagcttatg tgtcaaccta tactgttact 7980 agatcaggca ttagtgtctg atgttggtga tagtgcggaa gttgcagtta aaatgtttga 8040 tgcttacgtt aatacgtttt catcaacttt taacgtacca atggaaaaac tcaaaacact 8100 agttgcaact gcagaagctg aacttgcaaa gaatgtgtcc ttagacaatg tcttatctac 8160 ttttatttca gcagctcggc aagggtttgt tgattcagat gtagaaacta aagatgttgt 8220 tgaatgtctt aaattgtcac atcaatctga catagaagtt actggcgata gttgtaataa 8280 ctatatgctc acctataaca aagttgaaaa catgacaccc cgtgaccttg gtgcttgtat 8340 tgactgtagt gcgcgtcata ttaatgcgca ggtagcaaaa agtcacaaca ttgctttgat 8400 atggaacgtt aaagatttca tgtcattgtc tgaacaacta cgaaaacaaa tacgtagtgc 8460 tgctaaaaag aataacttac cttttaagtt gacatgtgca actactagac aagttgttaa 8520 tgttgtaaca acaaagatag cacttaaggg tggtaaaatt gttaataatt ggttgaagca 8580 gttaattaaa gttacacttg tgttcctttt tgttgctgct attttctatt taataacacc 8640 tgttcatgtc atgtctaaac atactgactt ttcaagtgaa atcataggat acaaggctat 8700 tgatggtggt gtcactcgtg acatagcatc tacagatact tgttttgcta acaaacatgc 8760 tgattttgac acatggttta gccagcgtgg tggtagttat actaatgaca aagcttgccc 8820 attgattgct gcagtcataa caagagaagt gggttttgtc gtgcctggtt tgcctggcac 8880 gatattacgc acaactaatg gtgacttttt gcatttctta cctagagttt ttagtgcagt 8940 tggtaacatc tgttacacac catcaaaact tatagagtac actgactttg caacatcagc 9000 ttgtgttttg gctgctgaat gtacaatttt taaagatgct tctggtaagc cagtaccata 9060 ttgttatgat accaatgtac tagaaggttc tgttgcttat gaaagtttac gccctgacac 9120 acgttatgtg ctcatggatg gctctattat tcaatttcct aacacctacc ttgaaggttc 9180 tgttagagtg gtaacaactt ttgattctga gtactgtagg cacggcactt gtgaaagatc 9240 agaagctggt gtttgtgtat ctactagtgg tagatgggta cttaacaatg attattacag 9300 atctttacca ggagttttct gtggtgtaga tgctgtaaat ttacttacta atatgtttac 9360 accactaatt caacctattg gtgctttgga catatcagca tctatagtag ctggtggtat 9420 tgtagctatc gtagtaacat gccttgccta ctattttatg aggtttagaa gagcttttgg 9480 tgaatacagt catgtagttg cctttaatac tttactattc cttatgtcat tcactgtact 9540 ctgtttaaca ccagtttact cattcttacc tggtgtttat tctgttattt acttgtactt 9600 gacattttat cttactaatg atgtttcttt tttagcacat attcagtgga tggttatgtt 9660 cacaccttta gtacctttct ggataacaat tgcttatatc atttgtattt ccacaaagca 9720 tttctattgg ttctttagta attacctaaa gagacgtgta gtctttaatg gtgtttcctt 9780 tagtactttt gaagaagctg cgctgtgcac ctttttgtta aataaagaaa tgtatctaaa 9840 gttgcgtagt gatgtgctat tacctcttac gcaatataat agatacttag ctctttataa 9900 taagtacaag tattttagtg gagcaatgga tacaactagc tacagagaag ctgcttgttg 9960 tcatctcgca aaggctctca atgacttcag taactcaggt tctgatgttc tttaccaacc 10020 accacaaacc tctatcacct cagctgtttt gcagagtggt tttagaaaaa tggcattccc 10080 atctggtaaa gttgagggtt gtatggtaca agtaacttgt ggtacaacta cacttaacgg 10140 tctttggctt gatgacgtag tttactgtcc aagacatgtg atctgcacct ctgaagacat 10200 gcttaaccct aattatgaag atttactcat tcgtaagtct aatcataatt tcttggtaca 10260 ggctggtaat gttcaactca gggttattgg acattctatg caaaattgtg tacttaagct 10320 taaggttgat acagccaatc ctaagacacc taagtataag tttgttcgca ttcaaccagg 10380 acagactttt tcagtgttag cttgttacaa tggttcacca tctggtgttt accaatgtgc 10440 tatgaggccc aatttcacta ttaagggttc attccttaat ggttcatgtg gtagtgttgg 10500 ttttaacata gattatgact gtgtctcttt ttgttacatg caccatatgg aattaccaac 10560 tggagttcat gctggcacag acttagaagg taacttttat ggaccttttg ttgacaggca 10620 aacagcacaa gcagctggta cggacacaac tattacagtt aatgttttag cttggttgta 10680 cgctgctgtt ataaatggag acaggtggtt tctcaatcga tttaccacaa ctcttaatga 10740 ctttaacctt gtggctatga agtacaatta tgaacctcta acacaagacc atgttgacat 10800 actaggacct ctttctgctc aaactggaat tgccgtttta gatatgtgtg cttcattaaa 10860 agaattactg caaaatggta tgaatggacg taccatattg ggtagtgctt tattagaaga 10920 tgaatttaca ccttttgatg ttgttagaca atgctcaggt gttactttcc aaagtgcagt 10980 gaaaagaaca atcaagggta cacaccactg gttgttactc acaattttga cttcactttt 11040 agttttagtc cagagtactc aatggtcttt gttctttttt ttgtatgaaa atgccttttt 11100 accttttgct atgggtatta ttgctatgtc tgcttttgca atgatgtttg tcaaacataa 11160 gcatgcattt ctctgtttgt ttttgttacc ttctcttgcc actgtagctt attttaatat 11220 ggtctatatg cctgctagtt gggtgatgcg tattatgaca tggttggata tggttgatac 11280 tagtttgtct ggttttaagc taaaagactg tgttatgtat gcatcagctg tagtgttact 11340 aatccttatg acagcaagaa ctgtgtatga tgatggtgct aggagagtgt ggacacttat 11400 gaatgtcttg acactcgttt ataaagttta ttatggtaat gctttagatc aagccatttc 11460 catgtgggct cttataatct ctgttacttc taactactca ggtgtagtta caactgtcat 11520 gtttttggcc agaggtattg tttttatgtg tgttgagtat tgccctattt tcttcataac 11580 tggtaataca cttcagtgta taatgctagt ttattgtttc ttaggctatt tttgtacttg 11640 ttactttggc ctcttttgtt tactcaaccg ctactttaga ctgactcttg gtgtttatga 11700 ttacttagtt tctacacagg agtttagata tatgaattca cagggactac tcccacccaa 11760 gaatagcata gatgccttca aactcaacat taaattgttg ggtgttggtg gcaaaccttg 11820 tatcaaagta gccactgtac agtctaaaat gtcagatgta aagtgcacat cagtagtctt 11880 actctcagtt ttgcaacaac tcagagtaga atcatcatct aaattgtggg ctcaatgtgt 11940 ccagttacac aatgacattc tcttagctaa agatactact gaagcctttg aaaaaatggt 12000 ttcactactt tctgttttgc tttccatgca gggtgctgta gacataaaca agctttgtga 12060 agaaatgctg gacaacaggg caaccttaca agctatagcc tcagagttta gttcccttcc 12120 atcatatgca gcttttgcta ctgctcaaga agcttatgag caggctgttg ctaatggtga 12180 ttctgaagtt gttcttaaaa agttgaagaa gtctttgaat gtggctaaat ctgaatttga 12240 ccgtgatgca gccatgcaac gtaagttgga aaagatggct gatcaagcta tgacccaaat 12300 gtataaacag gctagatctg aggacaagag ggcaaaagtt actagtgcta tgcagacaat 12360 gcttttcact atgcttagaa agttggataa tgatgcactc aacaacatta tcaacaatgc 12420 aagagatggt tgtgttccct tgaacataat acctcttaca acagcagcca aactaatggt 12480 tgtcatacca gactataaca catataaaaa tacgtgtgat ggtacaacat ttacttatgc 12540 atcagcattg tgggaaatcc aacaggttgt agatgcagat agtaaaattg ttcaacttag 12600 tgaaattagt atggacaatt cacctaattt agcatggcct cttattgtaa cagctttaag 12660 ggccaattct gctgtcaaat tacagaataa tgagcttagt cctgttgcac tacgacagat 12720 gtcttgtgct gccggtacta cacaaactgc ttgcactgat gacaatgcgt tagcttacta 12780 caacacaaca aagggaggta ggtttgtact tgcactgtta tccgatttac aggatttgaa 12840 atgggctaga ttccctaaga gtgatggaac tggtactatc tatacagaac tggaaccacc 12900 ttgtaggttt gttacagaca cacctaaagg tcctaaagtg aagtatttat actttattaa 12960 aggattaaac aacctaaata gaggtatggt acttggtagt ttagctgcca cagtacgtct 13020 acaagctggt aatgcaacag aagtgcctgc caattcaact gtattatctt tctgtgcttt 13080 tgctgtagat gctgctaaag cttacaaaga ttatctagct agtgggggac aaccaatcac 13140 taattgtgtt aagatgttgt gtacacacac tggtactggt caggcaataa cagttacacc 13200 ggaagccaat atggatcaag aatcctttgg tggtgcatcg tgttgtctgt actgccgttg 13260 ccacatagat catccaaatc ctaaaggatt ttgtgactta aaaggtaagt atgtacaaat 13320 acctacaact tgtgctaatg accctgtggg ttttacactt aaaaacacag tctgtaccgt 13380 ctgcggtatg tggaaaggtt atggctgtag ttgtgatcaa ctccgcgaac ccatgcttca 13440 gtcagctgat gcacaatcgt ttttaaacgg gtttgcggtg taagtgcagc ccgtcttaca 13500 ccgtgcggca caggcactag tactgatgtc gtatacaggg cttttgacat ctacaatgat 13560 aaagtagctg gttttgctaa attcctaaaa actaattgtt gtcgcttcca agaaaaggac 13620 gaagatgaca atttaattga ttcttacttt gtagttaaga gacacacttt ctctaactac 13680 caacatgaag aaacaattta taatttactt aaggattgtc cagctgttgc taaacatgac 13740 ttctttaagt ttagaataga cggtgacatg gtaccacata tatcacgtca acgtcttact 13800 aaatacacaa tggcagacct cgtctatgct ttaaggcatt ttgatgaagg taattgtgac 13860 acattaaaag aaatacttgt cacatacaat tgttgtgatg atgattattt caataaaaag 13920 gactggtatg attttgtaga aaacccagat atattacgcg tatacgccaa cttaggtgaa 13980 cgtgtacgcc aagctttgtt aaaaacagta caattctgtg atgccatgcg aaatgctggt 14040 attgttggtg tactgacatt agataatcaa gatctcaatg gtaactggta tgatttcggt 14100 gatttcatac aaaccacgcc aggtagtgga gttcctgttg tagattctta ttattcattg 14160 ttaatgccta tattaacctt gaccagggct ttaactgcag agtcacatgt tgacactgac 14220 ttaacaaagc cttacattaa gtgggatttg ttaaaatatg acttcacgga agagaggtta 14280 aaactctttg accgttattt taaatattgg gatcagacat accacccaaa ttgtgttaac 14340 tgtttggatg acagatgcat tctgcattgt gcaaacttta atgttttatt ctctacagtg 14400 ttcccaccta caagttttgg accactagtg agaaaaatat ttgttgatgg tgttccattt 14460 gtagtttcaa ctggatacca cttcagagag ctaggtgttg tacataatca ggatgtaaac 14520 ttacatagct ctagacttag ttttaaggaa ttacttgtgt atgctgctga ccctgctatg 14580 cacgctgctt ctggtaatct attactagat aaacgcacta cgtgcttttc agtagctgca 14640 cttactaaca atgttgcttt tcaaactgtc aaacccggta attttaacaa agacttctat 14700 gactttgctg tgtctaaggg tttctttaag gaaggaagtt ctgttgaatt aaaacacttc 14760 ttctttgctc aggatggtaa tgctgctatc agcgattatg actactatcg ttataatcta 14820 ccaacaatgt gtgatatcag acaactacta tttgtagttg aagttgttga taagtacttt 14880 gattgttacg atggtggctg tattaatgct aaccaagtca tcgtcaacaa cctagacaaa 14940 tcagctggtt ttccatttaa taaatggggt aaggctagac tttattatga ttcaatgagt 15000 tatgaggatc aagatgcact tttcgcatat acaaaacgta atgtcatccc tactataact 15060 caaatgaatc ttaagtatgc cattagtgca aagaatagag ctcgcaccgt agctggtgtc 15120 tctatctgta gtactatgac caatagacag tttcatcaaa aattattgaa atcaatagcc 15180 gccactagag gagctactgt agtaattgga acaagcaaat tctatggtgg ttggcacaac 15240 atgttaaaaa ctgtttatag tgatgtagaa aaccctcacc ttatgggttg ggattatcct 15300 aaatgtgata gagccatgcc taacatgctt agaattatgg cctcacttgt tcttgctcgc 15360 aaacatacaa cgtgttgtag cttgtcacac cgtttctata gattagctaa tgagtgtgct 15420 caagtattga gtgaaatggt catgtgtggc ggttcactat atgttaaacc aggtggaacc 15480 tcatcaggag atgccacaac tgcttatgct aatagtgttt ttaacatttg tcaagctgtc 15540 acggccaatg ttaatgcact tttatctact gatggtaaca aaattgccga taagtatgtc 15600 cgcaatttac aacacagact ttatgagtgt ctctatagaa atagagatgt tgacacagac 15660 tttgtgaatg agttttacgc atatttgcgt aaacatttct caatgatgat actctctgac 15720 gatgctgttg tgtgtttcaa tagcacttat gcatctcaag gtctagtggc tagcataaag 15780 aactttaagt cagttcttta ttatcaaaac aatgttttta tgtctgaagc aaaatgttgg 15840 actgagactg accttactaa aggacctcat gaattttgct ctcaacatac aatgctagtt 15900 aaacagggtg atgattatgt gtaccttcct tacccagatc catcaagaat cctaggggcc 15960 ggctgttttg tagatgatat cgtaaaaaca gatggtacac ttatgattga acggttcgtg 16020 tctttagcta tagatgctta cccacttact aaacatccta atcaggagta tgctgatgtc 16080 tttcatttgt acttacaata cataagaaag ctacatgatg agttaacagg acacatgtta 16140 gacatgtatt ctgttatgct tactaatgat aacacttcaa ggtattggga acctgagttt 16200 tatgaggcta tgtacacacc gcatacagtc ttacaggctg ttggggcttg tgttctttgc 16260 aattcacaga cttcattaag atgtggtgct tgcatacgta gaccattctt atgttgtaaa 16320 tgctgttacg accatgtcat atcaacatca cataaattag tcttgtctgt taatccgtat 16380 gtttgcaatg ctccaggttg tgatgtcaca gatgtgactc aactttactt aggaggtatg 16440 agctattatt gtaaatcaca taaaccaccc attagttttc cattgtgtgc taatggacaa 16500 gtttttggtt tatataaaaa tacatgtgtt ggtagcgata atgttactga ctttaatgca 16560 attgcaacat gtgactggac aaatgctggt gattacattt tagctaacac ctgtactgaa 16620 agactcaagc tttttgcagc agaaacgctc aaagctactg aggagacatt taaactgtct 16680 tatggtattg ctactgtacg tgaagtgctg tctgacagag aattacatct ttcatgggaa 16740 gttggtaaac ctagaccacc acttaaccga aattatgtct ttactggtta tcgtgtaact 16800 aaaaacagta aagtacaaat aggagagtac acctttgaaa aaggtgacta tggtgatgct 16860 gttgtttacc gaggtacaac aacttacaaa ttaaatgttg gtgattattt tgtgctgaca 16920 tcacatacag taatgccatt aagtgcacct acactagtgc cacaagagca ctatgttaga 16980 attactggct tatacccaac actcaatatc tcagatgagt tttctagcaa tgttgcaaat 17040 tatcaaaagg ttggtatgca aaagtattct acactccagg gaccacctgg tactggtaag 17100 agtcattttg ctattggcct agctctctac tacccttctg ctcgcatagt gtatacagct 17160 tgctctcatg ccgctgttga tgcactatgt gagaaggcat taaaatattt gcctatagat 17220 aaatgtagta gaattatacc tgcacgtgct cgtgtagagt gttttgataa attcaaagtg 17280 aattcaacat tagaacagta tgtcttttgt actgtaaatg cattgcctga gacgacagca 17340 gatatagttg tctttgatga aatttcaatg gccacaaatt atgatttgag tgttgtcaat 17400 gccagattac gtgctaagca ctatgtgtac attggcgacc ctgctcaatt acctgcacca 17460 cgcacattgc taactaaggg cacactagaa ccagaatatt tcaattcagt gtgtagactt 17520 atgaaaacta taggtccaga catgttcctc ggaacttgtc ggcgttgtcc tgctgaaatt 17580 gttgacactg tgagtgcttt ggtttatgat aataagctta aagcacataa agacaaatca 17640 gctcaatgct ttaaaatgtt ttataagggt gttatcacgc atgatgtttc atctgcaatt 17700 aacaggccac aaataggcgt ggtaagagaa ttccttacac gtaaccctgc ttggagaaaa 17760 gctgtcttta tttcacctta taattcacag aatgctgtag cctcaaagat tttgggacta 17820 ccaactcaaa ctgttgattc atcacagggc tcagaatatg actatgtcat attcactcaa 17880 accactgaaa cagctcactc ttgtaatgta aacagattta atgttgctat taccagagca 17940 aaagtaggca tactttgcat aatgtctgat agagaccttt atgacaagtt gcaatttaca 18000 agtcttgaaa ttccacgtag gaatgtggca actttacaag ctgaaaatgt aacaggactc 18060 tttaaagatt gtagtaaggt aatcactggg ttacatccta cacaggcacc tacacacctc 18120 agtgttgaca ctaaattcaa aactgaaggt ttatgtgttg acatacctgg catacctaag 18180 gacatgacct atagaagact catctctatg atgggtttta aaatgaatta tcaagttaat 18240 ggttacccta acatgtttat cacccgcgaa gaagctataa gacatgtacg tgcatggatt 18300 ggcttcgatg tcgaggggtg tcatgctact agagaagctg ttggtaccaa tttaccttta 18360 cagctaggtt tttctacagg tgttaaccta gttgctgtac ctacaggtta tgttgataca 18420 cctaataata cagatttttc cagagttagt gctaaaccac cgcctggaga tcaatttaaa 18480 cacctcatac cacttatgta caaaggactt ccttggaatg tagtgcgtat aaagattgta 18540 caaatgttaa gtgacacact taaaaatctc tctgacagag tcgtatttgt cttatgggca 18600 catggctttg agttgacatc tatgaagtat tttgtgaaaa taggacctga gcgcacctgt 18660 tgtctatgtg atagacgtgc cacatgcttt tccactgctt cagacactta tgcctgttgg 18720 catcattcta ttggatttga ttacgtctat aatccgttta tgattgatgt tcaacaatgg 18780 ggttttacag gtaacctaca aagcaaccat gatctgtatt gtcaagtcca tggtaatgca 18840 catgtagcta gttgtgatgc aatcatgact aggtgtctag ctgtccacga gtgctttgtt 18900 aagcgtgttg actggactat tgaatatcct ataattggtg atgaactgaa gattaatgcg 18960 gcttgtagaa aggttcaaca catggttgtt aaagctgcat tattagcaga caaattccca 19020 gttcttcacg acattggtaa ccctaaagct attaagtgtg tacctcaagc tgatgtagaa 19080 tggaagttct atgatgcaca gccttgtagt gacaaagctt ataaaataga agaattattc 19140 tattcttatg ccacacattc tgacaaattc acagatggtg tatgcctatt ttggaattgc 19200 aatgtcgata gatatcctgc taattccatt gtttgtagat ttgacactag agtgctatct 19260 aaccttaact tgcctggttg tgatggtggc agtttgtatg taaataaaca tgcattccac 19320 acaccagctt ttgataaaag tgcttttgtt aatttaaaac aattaccatt tttctattac 19380 tctgacagtc catgtgagtc tcatggaaaa caagtagtgt cagatataga ttatgtacca 19440 ctaaagtctg ctacgtgtat aacacgttgc aatttaggtg gtgctgtctg tagacatcat 19500 gctaatgagt acagattgta tctcgatgct tataacatga tgatctcagc tggctttagc 19560 ttgtgggttt acaaacaatt tgatacttat aacctctgga acacttttac aagacttcag 19620 agtttagaaa atgtggcttt taatgttgta aataagggac actttgatgg acaacagggt 19680 gaagtaccag tttctatcat taataacact gtttacacaa aagttgatgg tgttgatgta 19740 gaattgtttg aaaataaaac aacattacct gttaatgtag catttgagct ttgggctaag 19800 cgcaacatta aaccagtacc agaggtgaaa atactcaata atttgggtgt ggacattgct 19860 gctaatactg tgatctggga ctacaaaaga gatgctccag cacatatatc tactattggt 19920 gtttgttcta tgactgacat agccaagaaa ccaactgaaa cgatttgtgc accactcact 19980 gtcttttttg atggtagagt tgatggtcaa gtagacttat ttagaaatgc ccgtaatggt 20040 gttcttatta cagaaggtag tgttaaaggt ttacaaccat ctgtaggtcc caaacaagct 20100 agtcttaatg gagtcacatt aattggagaa gccgtaaaaa cacagttcaa ttattataag 20160 aaagttgatg gtgttgtcca acaattacct gaaacttact ttactcagag tagaaattta 20220 caagaattta aacccaggag tcaaatggaa attgatttct tagaattagc tatggatgaa 20280 ttcattgaac ggtataaatt agaaggctat gccttcgaac atatcgttta tggagatttt 20340 agtcatagtc agttaggtgg tttacatcta ctgattggac tagctaaacg ttttaaggaa 20400 tcaccttttg aattagaaga ttttattcct atggacagta cagttaaaaa ctatttcata 20460 acagatgcgc aaacaggttc atctaagtgt gtgtgttctg ttattgattt attacttgat 20520 gattttgttg aaataataaa atcccaagat ttatctgtag tttctaaggt tgtcaaagtg 20580 actattgact atacagaaat ttcatttatg ctttggtgta aagatggcca tgtagaaaca 20640 ttttacccaa aattacaatc tagtcaagcg tggcaaccgg gtgttgctat gcctaatctt 20700 tacaaaatgc aaagaatgct attagaaaag tgtgaccttc aaaattatgg tgatagtgca 20760 acattaccta aaggcataat gatgaatgtc gcaaaatata ctcaactgtg tcaatattta 20820 aacacattaa cattagctgt accctataat atgagagtta tacattttgg tgctggttct 20880 gataaaggag ttgcaccagg tacagctgtt ttaagacagt ggttgcctac gggtacgctg 20940 cttgtcgatt cagatcttaa tgactttgtc tctgatgcag attcaacttt gattggtgat 21000 tgtgcaactg tacatacagc taataaatgg gatctcatta ttagtgatat gtacgaccct 21060 aagactaaaa atgttacaaa agaaaatgac tctaaagagg gttttttcac ttacatttgt 21120 gggtttatac aacaaaagct agctcttgga ggttccgtgg ctataaagat aacagaacat 21180 tcttggaatg ctgatcttta taagctcatg ggacacttcg catggtggac agcctttgtt 21240 actaatgtga atgcgtcatc atctgaagca tttttaattg gatgtaatta tcttggcaaa 21300 ccacgcgaac aaatagatgg ttatgtcatg catgcaaatt acatattttg gaggaataca 21360 aatccaattc agttgtcttc ctattcttta tttgacatga gtaaatttcc ccttaaatta 21420 aggggtactg ctgttatgtc tttaaaagaa ggtcaaatca atgatatgat tttatctctt 21480 cttagtaaag gtagacttat aattagagaa aacaacagag ttgttatttc tagtgatgtt 21540 cttgttaaca actaaacgaa caatgtttgt ttttcttgtt ttattgccac tagtctctag 21600 tcagtgtgtt aatcttacaa ccagaactca attaccccct gcatacacta attctttcac 21660 acgtggtgtt tattaccctg acaaagtttt cagatcctca gttttacatt caactcagga 21720 cttgttctta cctttctttt ccaatgttac ttggttccat gctatacatg tctctgggac 21780 caatggtact aagaggtttg ataaccctgt cctaccattt aatgatggtg tttattttgc 21840 ttccactgag aagtctaaca taataagagg ctggattttt ggtactactt tagattcgaa 21900 gacccagtcc ctacttattg ttaataacgc tactaatgtt gttattaaag tctgtgaatt 21960 tcaattttgt aatgatccat ttttgggtgt ttattaccac aaaaacaaca aaagttggat 22020 ggaaagtgag ttcagagttt attctagtgc gaataattgc acttttgaat atgtctctca 22080 gccttttctt atggaccttg aaggaaaaca gggtaatttc aaaaatctta gggaatttgt 22140 gtttaagaat attgatggtt attttaaaat atattctaag cacacgccta ttaatttagt 22200 gcgtgatctc cctcagggtt tttcggcttt agaaccattg gtagatttgc caataggtat 22260 taacatcact aggtttcaaa ctttacttgc tttacataga agttatttga ctcctggtga 22320 ttcttcttca ggttggacag ctggtgctgc agcttattat gtgggttatc ttcaacctag 22380 gacttttcta ttaaaatata atgaaaatgg aaccattaca gatgctgtag actgtgcact 22440 tgaccctctc tcagaaacaa agtgtacgtt gaaatccttc actgtagaaa aaggaatcta 22500 tcaaacttct aactttagag tccaaccaac agaatctatt gttagatttc ctaatattac 22560 aaacttgtgc ccttttggtg aagtttttaa cgccaccaga tttgcatctg tttatgcttg 22620 gaacaggaag agaatcagca actgtgttgc tgattattct ttcctatata attccgcatc 22680 attttccact tttaagtgtt atggagtgtc tcctactaaa ttaaatgatc tctgctttac 22740 taatgtctat gcagattcat ttgtaattag aggtgatgaa gtcagacaaa tcgctccagg 22800 gcaaactgga aagattgctg attataatta taaattacca gatgatttta caggctgcgt 22860 tatagcttgg aattctaaca atcttgattc taaggttggt ggtaattata attacctgta 22920 tagattgttt aggaagtcta atctcaaacc ttttgagaga gatatttcaa ctgaaatcta 22980 tcaggccggt agcacacctt gtaatggtgt tgaaggtttt aattgttact ttcctttaca 23040 atcatatggt ttccaaccca ctaatggtgt tggttaccaa ccatacagag tagtagtact 23100 ttcttttgaa cttctacatg caccagcaac tgtttgtgga cctaaaaagt ctactaattt 23160 ggttaaaaac aaatgtgtca atttcaactt caatggttta acaggcacag gtgttcttac 23220 tgagtctaac aaaaagtttc tgcctttcca acaatttggc agagacattg ctgacactac 23280 tgatgctgtc cgtgatccac agacacttga gattcttgac attacaccat gttcttttgg 23340 tggtgtcagt gttataacac caggaacaaa tacttctaac caggttgctg ttctttatca 23400 ggatgttaac tgcacagaag tccctgttgc tattcatgca gatcaactta ctcctacttg 23460 gcgtgtttat tctacaggtt ctaatgtttt tcaaacacgt gcaggctgtt taataggggc 23520 tgaacatgtc aacaactcat atgagtgtga catacccatt ggtgcaggta tatgcgctag 23580 ttatcagact cagactaatt ctcctcggcg ggcacgtagt gtagctagtc aatccatcat 23640 tgcctacact atgtcacttg gtgcagaaaa ttcagttgct tactctaata actctattgc 23700 catacccaca aattttacta ttagtgttac cacagaaatt ctaccagtgt ctatgaccaa 23760 gacatcagta gattgtacaa tgtacatttg tggtgattca actgaatgca gcaatctttt 23820 gttgcaatat ggcagttttt gtacacaatt aaaccgtgct ttaactggaa tagctgttga 23880 acaagacaaa aacacccaag aagtttttgc acaagtcaaa caaatttaca aaacaccacc 23940 aattaaagat tttggtggtt ttaatttttc acaaatatta ccagatccat caaaaccaag 24000 caagaggtca tttattgaag atctactttt caacaaagtg acacttgcag atgctggctt 24060 catcaaacaa tatggtgatt gccttggtga tattgctgct agagacctca tttgtgcaca 24120 aaagtttaac ggccttactg ttttgccacc tttgctcaca gatgaaatga ttgctcaata 24180 cacttctgca ctgttagcgg gtacaatcac ttctggttgg acctttggtg caggtgctgc 24240 attacaaata ccatttgcta tgcaaatggc ttataggttt aatggtattg gagttacaca 24300 gaatgttctc tatgagaacc aaaaattgat tgccaaccaa tttaatagtg ctattggcaa 24360 aattcaagac tcactttctt ccacagcaag tgcacttgga aaacttcaag atgtggtcaa 24420 ccaaaatgca caagctttaa acacgcttgt taaacaactt agctccaatt ttggtgcaat 24480 ttcaagtgtt ttaaatgata tcctttcacg tcttgacaaa gttgaggctg aagtgcaaat 24540 tgataggttg atcacaggca gacttcaaag tttgcagaca tatgtgactc aacaattaat 24600 tagagctgca gaaatcagag cttctgctaa tcttgctgct actaaaatgt cagagtgtgt 24660 acttggacaa tcaaaaagag ttgatttttg tggaaagggc tatcatctta tgtccttccc 24720 tcagtcagca cctcatggtg tagtcttctt gcatgtgact tatgtccctg cacaagaaaa 24780 gaacttcaca actgctcctg ccatttgtca tgatggaaaa gcacactttc ctcgtgaagg 24840 tgtctttgtt tcaaatggca cacactggtt tgtaacacaa aggaattttt atgaaccaca 24900 aatcattact acagacaaca catttgtgtc tggtaactgt gatgttgtaa taggaattgt 24960 caacaacaca gtttatgatc ctttgcaacc tgaattagac tcattcaagg aggagttaga 25020 taaatatttt aagaatcata catcaccaga tgttgattta ggtgacatct ctggcattaa 25080 tgcttcagtt gtaaacattc aaaaagaaat tgaccgcctc aatgaggttg ccaagaattt 25140 aaatgaatct ctcatcgatc tccaagaact tggaaagtat gagcagtata taaaatggcc 25200 atggtacatt tggctaggtt ttatagctgg cttgattgcc atagtaatgg tgacaattat 25260 gctttgctgt atgaccagtt gctgtagttg tctcaagggc tgttgttctt gtggatcctg 25320 ctgcaaattt gatgaagacg actctgagcc agtgctcaaa ggagtcaaat tacattacac 25380 ataaacgaac ttatggattt gtttatgaga atcttcacaa ttggaactgt aactttgaag 25440 caaggtgaaa tcaaggatgc tactccttca gattttgttc gcgctactgc aacgataccg 25500 atacaagcct cactcccttt cggatggctt attgttggcg ttgcacttct tgctgttttt 25560 cagagcgctt ccaaaatcat aaccctcaaa aagagatggc aactagcact ctccaagggt 25620 gttcactttg tttgcaactt gctgttgttg tttgtaacag tttactcaca ccttttgctc 25680 gttgctgctg gccttgaagc cccttttctc tatctttatg ctttagtcta cttcttgcag 25740 agtataaact ttgtaagaat aataatgagg ctttggcttt gctggaaatg ccgttccaaa 25800 aacccattac tttatgatgc caactatttt ctttgctggc atactaattg ttacgactat 25860 tgtatacctt acaatagtgt aacttcttca attgtcatta cttcaggtga tggcacaaca 25920 agtcctattt ctgaacatga ctaccagatt ggtggttata ctgaaaaatg ggaatctgga 25980 gtaaaagact gtgttgtatt acacagttac ttcacttcag actattacca gctgtactca 26040 actcaattga gtacagacac tggtgttgaa catgttacct tcttcatcta caataaaatt 26100 gttgatgagc ctgaagaaca tgtccaaatt cacacaatcg acgtttcatc cggagttgtt 26160 aatccagtaa tggaaccaat ttatgatgaa ccgacgacga ctactagcgt gcctttgtaa 26220 gcacaagctg atgagtacga acttatgtac tcattcgttt cggaagagac aggtacgtta 26280 atagttaata gcgtacttct ttttcttgct ttcgtggtat tcttgctagt tacactagcc 26340 atccttactg cgcttcgatt gtgtgcgtac tgctgcaata ttgttaacgt gagtcttgta 26400 aaaccttctt tttacgttta ctctcgtgtt aaaaatctga attcttctag agttcctgat 26460 cttctggtct aaacgaacta aatattatat tagtttttct gtttggaact ttaattttag 26520 ccatggcaga ttccaacggt actattaccg ttgaagagct taaaaagctc cttgaacaat 26580 ggaacctagt aataggtttc ctattcctta catggatttg tcttctacaa tttgcctatg 26640 ccaacaggaa taggtttttg tatataatta agttaatttt cctctggctg ttatggccag 26700 taactttagc ttgttttgtg cttgctgctg tttacagaat aaattggatc accggtggaa 26760 ttgctatcgc aatggcttgt cttgtaggct tgatgtggct cagctacttc attgcttctt 26820 tcagactgtt tgcgcgtacg cgttccatgt ggtcattcaa tccagaaact aacattcttc 26880 tcaacgtgcc actccatggc actattctga ccagaccgct tctagaaagt gaactcgtaa 26940 tcggagctgt gatccttcgt ggacatcttc gtattgctgg acaccatcta ggacgctgtg 27000 acatcaagga cctgcctaaa gaaatcactg ttgctacatc acgaacgctt tcttattaca 27060 aattgggagc ttcgcagcgt gtagcaggtg actcaggttt tgctgcatac agtcgctaca 27120 ggattggcaa ctataaatta aacacagacc attccagtag cagtgacaat attgctttgc 27180 ttgtacagta agtgacaaca gatgtttcat ctcgttgact ttcaggttac tatagcagag 27240 atattactaa ttattatgag gacttttaaa gtttccattt ggaatcttga ttacatcata 27300 aacctcataa ttaaaaattt atctaagtca ctaactgaga ataaatattc tcaattagat 27360 gaagagcaac caatggagat tgattaaacg aacatgaaaa ttattctttt cttggcactg 27420 ataacactcg ctacttgtga gctttatcac taccaagagt gtgttagagg tacaacagta 27480 cttttaaaag aaccttgctc ttctggaaca tacgagggca attcaccatt tcatcctcta 27540 gctgataaca aatttgcact gacttgcttt agcactcaat ttgcttttgc ttgtcctgac 27600 ggcgtaaaac acgtctatca gttacgtgcc agatcagttt cacctaaact gttcatcaga 27660 caagaggaag ttcaagaact ttactctcca atttttctta ttgttgcggc aatagtgttt 27720 ataacacttt gcttcacact caaaagaaag acagaatgat tgaactttca ttaattgact 27780 tctatttgtg ctttttagcc tttctgctat tccttgtttt aattatgctt attatctttt 27840 ggttctcact tgaactgcaa gatcataatg aaacttgtca cgcctaaacg aacatgaaat 27900 ttcttgtttt cttaggaatc atcacaactg tagctgcatt tcaccaagaa tgtagtttac 27960 agtcatgtac tcaacatcaa ccatatgtag ttgatgaccc gtgtcctatt cacttctatt 28020 ctaaatggta tattagagta ggagctagaa aatcagcacc tttaattgaa ttgtgcgtgg 28080 atgaggctgg ttctaaatca cccattcagt acatcgatat cggtaattat acagtttcct 28140 gtttaccttt tacaattaat tgccaggaac ctaaattggg tagtcttgta gtgcgttgtt 28200 cgttctatga agacttttta gagtatcatg acgttcgtgt tgttttagat ttcatctaaa 28260 cgaacaaact aaaatgtctg ataatggacc ccaaaatcag cgaaatgcac cccgcattac 28320 gtttggtgga ccctcagatt caactggcag taaccagaat ggagaacgca gtggggcgcg 28380 atcaaaacaa cgtcggcccc aaggtttacc caataatact gcgtcttggt tcaccgctct 28440 cactcaacat ggcaaggaag accttaaatt ccctcgagga caaggcgttc caattaacac 28500 caatagcagt ccagatgacc aaattggcta ctaccgaaga gctaccagac gaattcgtgg 28560 tggtgacggt aaaatgaaag atctcagtcc aagatggtat ttctactacc taggaactgg 28620 gccagaagct ggacttccct atggtgctaa caaagacggc atcatatggg ttgcaactga 28680 gggagccttg aatacaccaa aagatcacat tggcacccgc aatcctgcta acaatgctgc 28740 aatcgtgcta caacttcctc aaggaacaac attgccaaaa ggcttctacg cagaagggag 28800 cagaggcggc agtcaagcct cttctcgttc ctcatcacgt agtcgcaaca gttcaagaaa 28860 ttcaactcca ggcagcagta ggggaacttc tcctgctaga atggctggca atggcggtga 28920 tgctgctctt gctttgctgc tgcttgacag attgaaccag cttgagagca aaatgtctgg 28980 taaaggccaa caacaacaag gccaaactgt cactaagaaa tctgctgctg aggcttctaa 29040 gaagcctcgg caaaaacgta ctgccactaa agcatacaat gtaacacaag ctttcggcag 29100 acgtggtcca gaacaaaccc aaggaaattt tggggaccag gaactaatca gacaaggaac 29160 tgattacaaa cattggccgc aaattgcaca atttgccccc agcgcttcag cgttcttcgg 29220 aatgtcgcgc attggcatgg aagtcacacc ttcgggaacg tggttgacct acacaggtgc 29280 catcaaattg gatgacaaag atccaaattt caaagatcaa gtcattttgc tgaataagca 29340 tattgacgca tacaaaacat tcccaccaac agagcctaaa aaggacaaaa agaagaaggc 29400 tgatgaaact caagccttac cgcagagaca gaagaaacag caaactgtga ctcttcttcc 29460 tgctgcagat ttggatgatt tctccaaaca attgcaacaa tccatgagca gtgctgactc 29520 aactcaggcc taaactcatg cagaccacac aaggcagatg ggctatataa acgttttcgc 29580 ttttccgttt acgatatata gtctactctt gtgcagaatg aattctcgta actacatagc 29640 acaagtagat gtagttaact ttaatctcac atagcaatct ttaatcagtg tgtaacatta 29700 gggaggactt gaaagagcca ccacattttc accgaggcca cgcggagtac gatcgagtgt 29760 acagtgaaca atgctaggga gagctgccta tatggaagag ccctaatgtg taaaattaat 29820 tttagtagtg ctatccccat gtgattttaa tagcttctta ggagaatgac aaaa 29874 <210> 13 <211> 4405 <212> PRT <213> SARS-CoV2 <400> 13 Met Glu Ser Leu Val Pro Gly Phe Asn Glu Lys Thr Hes Val Gln Leu 1 5 10 15 Ser Leu Pro Val Leu Gln Val Arg Asp Val Leu Val Arg Gly Phe Gly 20 25 30 Asp Ser Val Glu Glu Val Leu Ser Glu Ala Arg Gln Hes Leu Lys Asp 35 40 45 Gly Thr Cys Gly Leu Val Glu Val Glu Lys Gly Val Leu Pro Gln Leu 50 55 60 Glu Gln Pro Tyr Val Phe Ile Lys Arg Ser Asp Ala Arg Thr Ala Pro 65 70 75 80 Hes Gly Hes Val Met Val Glu Leu Val Ala Glu Leu Glu Gly Ile Gln 85 90 95 Tyr Gly Arg Ser Gly Glu Thr Leu Gly Val Leu Val Pro Hes Val Gly 100 105 110 Glu Ile Pro Val Ala Tyr Arg Lys Val Leu Leu Arg Lys Asn Gly Asn 115 120 125 Lys Gly Ala Gly Gly Hes Ser Tyr Gly Ala Asp Leu Lys Ser Phe Asp 130 135 140 Leu Gly Asp Glu Leu Gly Thr Asp Pro Tyr Glu Asp Phe Gln Glu Asn 145 150 155 160 Trp Asn Thr Lys Hes Ser Ser Gly Val Thr Arg Glu Leu Met Arg Glu 165 170 175 Leu Asn Gly Gly Ala Tyr Thr Arg Tyr Val Asp Asn Asn Phe Cys Gly 180 185 190 Pro Asp Gly Tyr Pro Leu Glu Cys Ile Lys Asp Leu Leu Ala Arg Ala 195 200 205 Gly Lys Ala Ser Cys Thr Leu Ser Glu Gln Leu Asp Phe Ile Asp Thr 210 215 220 Lys Arg Gly Val Tyr Cys Cys Arg Glu Hes Glu Hes Glu Ile Ala Trp 225 230 235 240 Tyr Thr Glu Arg Ser Glu Lys Ser Tyr Glu Leu Gln Thr Pro Phe Glu 245 250 255 Ile Lys Leu Ala Lys Lys Phe Asp Thr Phe Asn Gly Glu Cys Pro Asn 260 265 270 Phe Val Phe Pro Leu Asn Ser Ile Ile Lys Thr Ile Gln Pro Arg Val 275 280 285 Glu Lys Lys Lys Leu Asp Gly Phe Met Gly Arg Ile Arg Ser Val Tyr 290 295 300 Pro Val Ala Ser Pro Asn Glu Cys Asn Gln Met Cys Leu Ser Thr Leu 305 310 315 320 Met Lys Cys Asp Hes Cys Gly Glu Thr Ser Trp Gln Thr Gly Asp Phe 325 330 335 Val Lys Ala Thr Cys Glu Phe Cys Gly Thr Glu Asn Leu Thr Lys Glu 340 345 350 Gly Ala Thr Thr Cys Gly Tyr Leu Pro Gln Asn Ala Val Val Lys Ile 355 360 365 Tyr Cys Pro Ala Cys Hes Asn Ser Glu Val Gly Pro Glu Hes Ser Leu 370 375 380 Ala Glu Tyr Hes Asn Glu Ser Gly Leu Lys Thr Ile Leu Arg Lys Gly 385 390 395 400 Gly Arg Thr Ile Ala Phe Gly Gly Cys Val Phe Ser Tyr Val Gly Cys 405 410 415 Hes Asn Lys Cys Ala Tyr Trp Val Pro Arg Ala Ser Ala Asn Ile Gly 420 425 430 Cys Asn Hes Thr Gly Val Val Gly Glu Gly Ser Glu Gly Leu Asn Asp 435 440 445 Asn Leu Leu Glu Ile Leu Gln Lys Glu Lys Val Asn Ile Asn Ile Val 450 455 460 Gly Asp Phe Lys Leu Asn Glu Glu Ile Ala Ile Ile Leu Ala Ser Phe 465 470 475 480 Ser Ala Ser Thr Ser Ala Phe Val Glu Thr Val Lys Gly Leu Asp Tyr 485 490 495 Lys Ala Phe Lys Gln Ile Val Glu Ser Cys Gly Asn Phe Lys Val Thr 500 505 510 Lys Gly Lys Ala Lys Lys Gly Ala Trp Asn Ile Gly Glu Gln Lys Ser 515 520 525 Ile Leu Ser Pro Leu Tyr Ala Phe Ala Ser Glu Ala Ala Arg Val Val 530 535 540 Arg Ser Ile Phe Ser Arg Thr Leu Glu Thr Ala Gln Asn Ser Val Arg 545 550 555 560 Val Leu Gln Lys Ala Ala Ile Thr Ile Leu Asp Gly Ile Ser Gln Tyr 565 570 575 Ser Leu Arg Leu Ile Asp Ala Met Met Phe Thr Ser Asp Leu Ala Thr 580 585 590 Asn Asn Leu Val Val Met Ala Tyr Ile Thr Gly Gly Val Val Gln Leu 595 600 605 Thr Ser Gln Trp Leu Thr Asn Ile Phe Gly Thr Val Tyr Glu Lys Leu 610 615 620 Lys Pro Val Leu Asp Trp Leu Glu Glu Lys Phe Lys Glu Gly Val Glu 625 630 635 640 Phe Leu Arg Asp Gly Trp Glu Ile Val Lys Phe Ile Ser Thr Cys Ala 645 650 655 Cys Glu Ile Val Gly Gly Gln Ile Val Thr Cys Ala Lys Glu Ile Lys 660 665 670 Glu Ser Val Gln Thr Phe Phe Lys Leu Val Asn Lys Phe Leu Ala Leu 675 680 685 Cys Ala Asp Ser Ile Ile Ile Gly Gly Ala Lys Leu Lys Ala Leu Asn 690 695 700 Leu Gly Glu Thr Phe Val Thr Hes Ser Lys Gly Leu Tyr Arg Lys Cys 705 710 715 720 Val Lys Ser Arg Glu Glu Thr Gly Leu Leu Met Pro Leu Lys Ala Pro 725 730 735 Lys Glu Ile Ile Phe Leu Glu Gly Glu Thr Leu Pro Thr Glu Val Leu 740 745 750 Thr Glu Glu Val Val Leu Lys Thr Gly Asp Leu Gln Pro Leu Glu Gln 755 760 765 Pro Thr Ser Glu Ala Val Glu Ala Pro Leu Val Gly Thr Pro Val Cys 770 775 780 Ile Asn Gly Leu Met Leu Leu Glu Ile Lys Asp Thr Glu Lys Tyr Cys 785 790 795 800 Ala Leu Ala Pro Asn Met Met Val Thr Asn Asn Thr Phe Thr Leu Lys 805 810 815 Gly Gly Ala Pro Thr Lys Val Thr Phe Gly Asp Asp Thr Val Ile Glu 820 825 830 Val Gln Gly Tyr Lys Ser Val Asn Ile Thr Phe Glu Leu Asp Glu Arg 835 840 845 Ile Asp Lys Val Leu Asn Glu Lys Cys Ser Ala Tyr Thr Val Glu Leu 850 855 860 Gly Thr Glu Val Asn Glu Phe Ala Cys Val Val Ala Asp Ala Val Ile 865 870 875 880 Lys Thr Leu Gln Pro Val Ser Glu Leu Leu Thr Pro Leu Gly Ile Asp 885 890 895 Leu Asp Glu Trp Ser Met Ala Thr Tyr Tyr Leu Phe Asp Glu Ser Gly 900 905 910 Glu Phe Lys Leu Ala Ser Hes Met Tyr Cys Ser Phe Tyr Pro Pro Asp 915 920 925 Glu Asp Glu Glu Glu Gly Asp Cys Glu Glu Glu Glu Phe Glu Pro Ser 930 935 940 Thr Gln Tyr Glu Tyr Gly Thr Glu Asp Asp Tyr Gln Gly Lys Pro Leu 945 950 955 960 Glu Phe Gly Ala Thr Ser Ala Ala Leu Gln Pro Glu Glu Glu Gln Glu 965 970 975 Glu Asp Trp Leu Asp Asp Asp Ser Gln Gln Thr Val Gly Gln Gln Asp 980 985 990 Gly Ser Glu Asp Asn Gln Thr Thr Thr Ile Gln Thr Ile Val Glu Val 995 1000 1005 Gln Pro Gln Leu Glu Met Glu Leu Thr Pro Val Val Gln Thr Ile 1010 1015 1020 Glu Val Asn Ser Phe Ser Gly Tyr Leu Lys Leu Thr Asp Asn Val 1025 1030 1035 Tyr Ile Lys Asn Ala Asp Ile Val Glu Glu Ala Lys Lys Val Lys 1040 1045 1050 Pro Thr Val Val Val Asn Ala Ala Asn Val Tyr Leu Lys Hes Gly 1055 1060 1065 Gly Gly Val Ala Gly Ala Leu Asn Lys Ala Thr Asn Asn Ala Met 1070 1075 1080 Gln Val Glu Ser Asp Asp Tyr Ile Ala Thr Asn Gly Pro Leu Lys 1085 1090 1095 Val Gly Gly Ser Cys Val Leu Ser Gly Hes Asn Leu Ala Lys Hes 1100 1105 1110 Cys Leu Hes Val Val Gly Pro Asn Val Asn Lys Gly Glu Asp Ile 1115 1120 1125 Gln Leu Leu Lys Ser Ala Tyr Glu Asn Phe Asn Gln Hes Glu Val 1130 1135 1140 Leu Leu Ala Pro Leu Leu Ser Ala Gly Ile Phe Gly Ala Asp Pro 1145 1150 1155 Ile Hes Ser Leu Arg Val Cys Val Asp Thr Val Arg Thr Asn Val 1160 1165 1170 Tyr Leu Ala Val Phe Asp Lys Asn Leu Tyr Asp Lys Leu Val Ser 1175 1180 1185 Ser Phe Leu Glu Met Lys Ser Glu Lys Gln Val Glu Gln Lys Ile 1190 1195 1200 Ala Glu Ile Pro Lys Glu Glu Val Lys Pro Phe Ile Thr Glu Ser 1205 1210 1215 Lys Pro Ser Val Glu Gln Arg Lys Gln Asp Asp Lys Lys Ile Lys 1220 1225 1230 Ala Cys Val Glu Glu Val Thr Thr Thr Leu Glu Glu Thr Lys Phe 1235 1240 1245 Leu Thr Glu Asn Leu Leu Leu Tyr Ile Asp Ile Asn Gly Asn Leu 1250 1255 1260 Hes Pro Asp Ser Ala Thr Leu Val Ser Asp Ile Asp Ile Thr Phe 1265 1270 1275 Leu Lys Lys Asp Ala Pro Tyr Ile Val Gly Asp Val Val Gln Glu 1280 1285 1290 Gly Val Leu Thr Ala Val Val Ile Pro Thr Lys Lys Ala Gly Gly 1295 1300 1305 Thr Thr Glu Met Leu Ala Lys Ala Leu Arg Lys Val Pro Thr Asp 1310 1315 1320 Asn Tyr Ile Thr Thr Tyr Pro Gly Gln Gly Leu Asn Gly Tyr Thr 1325 1330 1335 Val Glu Glu Ala Lys Thr Val Leu Lys Lys Cys Lys Ser Ala Phe 1340 1345 1350 Tyr Ile Leu Pro Ser Ile Ile Ser Asn Glu Lys Gln Glu Ile Leu 1355 1360 1365 Gly Thr Val Ser Trp Asn Leu Arg Glu Met Leu Ala Hes Ala Glu 1370 1375 1380 Glu Thr Arg Lys Leu Met Pro Val Cys Val Glu Thr Lys Ala Ile 1385 1390 1395 Val Ser Thr Ile Gln Arg Lys Tyr Lys Gly Ile Lys Ile Gln Glu 1400 1405 1410 Gly Val Val Asp Tyr Gly Ala Arg Phe Tyr Phe Tyr Thr Ser Lys 1415 1420 1425 Thr Thr Val Ala Ser Leu Ile Asn Thr Leu Asn Asp Leu Asn Glu 1430 1435 1440 Thr Leu Val Thr Met Pro Leu Gly Tyr Val Thr Hes Gly Leu Asn 1445 1450 1455 Leu Glu Glu Ala Ala Arg Tyr Met Arg Ser Leu Lys Val Pro Ala 1460 1465 1470 Thr Val Ser Val Ser Ser Pro Asp Ala Val Thr Ala Tyr Asn Gly 1475 1480 1485 Tyr Leu Thr Ser Ser Ser Lys Thr Pro Glu Glu Hes Phe Ile Glu 1490 1495 1500 Thr Ile Ser Leu Ala Gly Ser Tyr Lys Asp Trp Ser Tyr Ser Gly 1505 1510 1515 Gln Ser Thr Gln Leu Gly Ile Glu Phe Leu Lys Arg Gly Asp Lys 1520 1525 1530 Ser Val Tyr Tyr Thr Ser Asn Pro Thr Thr Phe Hes Leu Asp Gly 1535 1540 1545 Glu Val Ile Thr Phe Asp Asn Leu Lys Thr Leu Leu Ser Leu Arg 1550 1555 1560 Glu Val Arg Thr Ile Lys Val Phe Thr Thr Val Asp Asn Ile Asn 1565 1570 1575 Leu Hes Thr Gln Val Val Asp Met Ser Met Thr Tyr Gly Gln Gln 1580 1585 1590 Phe Gly Pro Thr Tyr Leu Asp Gly Ala Asp Val Thr Lys Ile Lys 1595 1600 1605 Pro Hes Asn Ser Hes Glu Gly Lys Thr Phe Tyr Val Leu Pro Asn 1610 1615 1620 Asp Asp Thr Leu Arg Val Glu Ala Phe Glu Tyr Tyr Hes Thr Thr 1625 1630 1635 Asp Pro Ser Phe Leu Gly Arg Tyr Met Ser Ala Leu Asn Hes Thr 1640 1645 1650 Lys Lys Trp Lys Tyr Pro Gln Val Asn Gly Leu Thr Ser Ile Lys 1655 1660 1665 Trp Ala Asp Asn Asn Cys Tyr Leu Ala Thr Ala Leu Leu Thr Leu 1670 1675 1680 Gln Gln Ile Glu Leu Lys Phe Asn Pro Pro Ala Leu Gln Asp Ala 1685 1690 1695 Tyr Tyr Arg Ala Arg Ala Gly Glu Ala Ala Asn Phe Cys Ala Leu 1700 1705 1710 Ile Leu Ala Tyr Cys Asn Lys Thr Val Gly Glu Leu Gly Asp Val 1715 1720 1725 Arg Glu Thr Met Ser Tyr Leu Phe Gln Hes Ala Asn Leu Asp Ser 1730 1735 1740 Cys Lys Arg Val Leu Asn Val Val Cys Lys Thr Cys Gly Gln Gln 1745 1750 1755 Gln Thr Thr Leu Lys Gly Val Glu Ala Val Met Tyr Met Gly Thr 1760 1765 1770 Leu Ser Tyr Glu Gln Phe Lys Lys Gly Val Gln Ile Pro Cys Thr 1775 1780 1785 Cys Gly Lys Gln Ala Thr Lys Tyr Leu Val Gln Gln Glu Ser Pro 1790 1795 1800 Phe Val Met Met Ser Ala Pro Pro Ala Gln Tyr Glu Leu Lys Hes 1805 1810 1815 Gly Thr Phe Thr Cys Ala Ser Glu Tyr Thr Gly Asn Tyr Gln Cys 1820 1825 1830 Gly Hes Tyr Lys Hes Ile Thr Ser Lys Glu Thr Leu Tyr Cys Ile 1835 1840 1845 Asp Gly Ala Leu Leu Thr Lys Ser Ser Glu Tyr Lys Gly Pro Ile 1850 1855 1860 Thr Asp Val Phe Tyr Lys Glu Asn Ser Tyr Thr Thr Thr Ile Lys 1865 1870 1875 Pro Val Thr Tyr Lys Leu Asp Gly Val Val Cys Thr Glu Ile Asp 1880 1885 1890 Pro Lys Leu Asp Asn Tyr Tyr Lys Lys Asp Asn Ser Tyr Phe Thr 1895 1900 1905 Glu Gln Pro Ile Asp Leu Val Pro Asn Gln Pro Tyr Pro Asn Ala 1910 1915 1920 Ser Phe Asp Asn Phe Lys Phe Val Cys Asp Asn Ile Lys Phe Ala 1925 1930 1935 Asp Asp Leu Asn Gln Leu Thr Gly Tyr Lys Lys Pro Ala Ser Arg 1940 1945 1950 Glu Leu Lys Val Thr Phe Phe Pro Asp Leu Asn Gly Asp Val Val 1955 1960 1965 Ala Ile Asp Tyr Lys Hes Tyr Thr Pro Ser Phe Lys Lys Gly Ala 1970 1975 1980 Lys Leu Leu Hes Lys Pro Ile Val Trp Hes Val Asn Asn Ala Thr 1985 1990 1995 Asn Lys Ala Thr Tyr Lys Pro Asn Thr Trp Cys Ile Arg Cys Leu 2000 2005 2010 Trp Ser Thr Lys Pro Val Glu Thr Ser Asn Ser Phe Asp Val Leu 2015 2020 2025 Lys Ser Glu Asp Ala Gln Gly Met Asp Asn Leu Ala Cys Glu Asp 2030 2035 2040 Leu Lys Pro Val Ser Glu Glu Val Val Glu Asn Pro Thr Ile Gln 2045 2050 2055 Lys Asp Val Leu Glu Cys Asn Val Lys Thr Thr Glu Val Val Gly 2060 2065 2070 Asp Ile Ile Leu Lys Pro Ala Asn Asn Ser Leu Lys Ile Thr Glu 2075 2080 2085 Glu Val Gly Hes Thr Asp Leu Met Ala Ala Tyr Val Asp Asn Ser 2090 2095 2100 Ser Leu Thr Ile Lys Lys Pro Asn Glu Leu Ser Arg Val Leu Gly 2105 2110 2115 Leu Lys Thr Leu Ala Thr Hes Gly Leu Ala Ala Val Asn Ser Val 2120 2125 2130 Pro Trp Asp Thr Ile Ala Asn Tyr Ala Lys Pro Phe Leu Asn Lys 2135 2140 2145 Val Val Ser Thr Thr Thr Asn Ile Val Thr Arg Cys Leu Asn Arg 2150 2155 2160 Val Cys Thr Asn Tyr Met Pro Tyr Phe Phe Thr Leu Leu Leu Gln 2165 2170 2175 Leu Cys Thr Phe Thr Arg Ser Thr Asn Ser Arg Ile Lys Ala Ser 2180 2185 2190 Met Pro Thr Thr Ile Ala Lys Asn Thr Val Lys Ser Val Gly Lys 2195 2200 2205 Phe Cys Leu Glu Ala Ser Phe Asn Tyr Leu Lys Ser Pro Asn Phe 2210 2215 2220 Ser Lys Leu Ile Asn Ile Ile Ile Trp Phe Leu Leu Leu Ser Val 2225 2230 2235 Cys Leu Gly Ser Leu Ile Tyr Ser Thr Ala Ala Leu Gly Val Leu 2240 2245 2250 Met Ser Asn Leu Gly Met Pro Ser Tyr Cys Thr Gly Tyr Arg Glu 2255 2260 2265 Gly Tyr Leu Asn Ser Thr Asn Val Thr Ile Ala Thr Tyr Cys Thr 2270 2275 2280 Gly Ser Ile Pro Cys Ser Val Cys Leu Ser Gly Leu Asp Ser Leu 2285 2290 2295 Asp Thr Tyr Pro Ser Leu Glu Thr Ile Gln Ile Thr Ile Ser Ser 2300 2305 2310 Phe Lys Trp Asp Leu Thr Ala Phe Gly Leu Val Ala Glu Trp Phe 2315 2320 2325 Leu Ala Tyr Ile Leu Phe Thr Arg Phe Phe Tyr Val Leu Gly Leu 2330 2335 2340 Ala Ala Ile Met Gln Leu Phe Phe Ser Tyr Phe Ala Val Hes Phe 2345 2350 2355 Ile Ser Asn Ser Trp Leu Met Trp Leu Ile Ile Asn Leu Val Gln 2360 2365 2370 Met Ala Pro Ile Ser Ala Met Val Arg Met Tyr Ile Phe Phe Ala 2375 2380 2385 Ser Phe Tyr Tyr Val Trp Lys Ser Tyr Val Hes Val Val Asp Gly 2390 2395 2400 Cys Asn Ser Ser Thr Cys Met Met Cys Tyr Lys Arg Asn Arg Ala 2405 2410 2415 Thr Arg Val Glu Cys Thr Thr Ile Val Asn Gly Val Arg Arg Ser 2420 2425 2430 Phe Tyr Val Tyr Ala Asn Gly Gly Lys Gly Phe Cys Lys Leu Hes 2435 2440 2445 Asn Trp Asn Cys Val Asn Cys Asp Thr Phe Cys Ala Gly Ser Thr 2450 2455 2460 Phe Ile Ser Asp Glu Val Ala Arg Asp Leu Ser Leu Gln Phe Lys 2465 2470 2475 Arg Pro Ile Asn Pro Thr Asp Gln Ser Ser Tyr Ile Val Asp Ser 2480 2485 2490 Val Thr Val Lys Asn Gly Ser Ile Hes Leu Tyr Phe Asp Lys Ala 2495 2500 2505 Gly Gln Lys Thr Tyr Glu Arg Hes Ser Leu Ser Hes Phe Val Asn 2510 2515 2520 Leu Asp Asn Leu Arg Ala Asn Asn Thr Lys Gly Ser Leu Pro Ile 2525 2530 2535 Asn Val Ile Val Phe Asp Gly Lys Ser Lys Cys Glu Glu Ser Ser 2540 2545 2550 Ala Lys Ser Ala Ser Val Tyr Tyr Ser Gln Leu Met Cys Gln Pro 2555 2560 2565 Ile Leu Leu Leu Asp Gln Ala Leu Val Ser Asp Val Gly Asp Ser 2570 2575 2580 Ala Glu Val Ala Val Lys Met Phe Asp Ala Tyr Val Asn Thr Phe 2585 2590 2595 Ser Ser Thr Phe Asn Val Pro Met Glu Lys Leu Lys Thr Leu Val 2600 2605 2610 Ala Thr Ala Glu Ala Glu Leu Ala Lys Asn Val Ser Leu Asp Asn 2615 2620 2625 Val Leu Ser Thr Phe Ile Ser Ala Ala Arg Gln Gly Phe Val Asp 2630 2635 2640 Ser Asp Val Glu Thr Lys Asp Val Val Glu Cys Leu Lys Leu Ser 2645 2650 2655 Hes Gln Ser Asp Ile Glu Val Thr Gly Asp Ser Cys Asn Asn Tyr 2660 2665 2670 Met Leu Thr Tyr Asn Lys Val Glu Asn Met Thr Pro Arg Asp Leu 2675 2680 2685 Gly Ala Cys Ile Asp Cys Ser Ala Arg Hes Ile Asn Ala Gln Val 2690 2695 2700 Ala Lys Ser Hes Asn Ile Ala Leu Ile Trp Asn Val Lys Asp Phe 2705 2710 2715 Met Ser Leu Ser Glu Gln Leu Arg Lys Gln Ile Arg Ser Ala Ala 2720 2725 2730 Lys Lys Asn Asn Leu Pro Phe Lys Leu Thr Cys Ala Thr Thr Arg 2735 2740 2745 Gln Val Val Asn Val Val Thr Thr Lys Ile Ala Leu Lys Gly Gly 2750 2755 2760 Lys Ile Val Asn Asn Trp Leu Lys Gln Leu Ile Lys Val Thr Leu 2765 2770 2775 Val Phe Leu Phe Val Ala Ala Ile Phe Tyr Leu Ile Thr Pro Val 2780 2785 2790 Hes Val Met Ser Lys Hes Thr Asp Phe Ser Ser Glu Ile Ile Gly 2795 2800 2805 Tyr Lys Ala Ile Asp Gly Gly Val Thr Arg Asp Ile Ala Ser Thr 2810 2815 2820 Asp Thr Cys Phe Ala Asn Lys Hes Ala Asp Phe Asp Thr Trp Phe 2825 2830 2835 Ser Gln Arg Gly Gly Ser Tyr Thr Asn Asp Lys Ala Cys Pro Leu 2840 2845 2850 Ile Ala Ala Val Ile Thr Arg Glu Val Gly Phe Val Val Pro Gly 2855 2860 2865 Leu Pro Gly Thr Ile Leu Arg Thr Thr Asn Gly Asp Phe Leu Hes 2870 2875 2880 Phe Leu Pro Arg Val Phe Ser Ala Val Gly Asn Ile Cys Tyr Thr 2885 2890 2895 Pro Ser Lys Leu Ile Glu Tyr Thr Asp Phe Ala Thr Ser Ala Cys 2900 2905 2910 Val Leu Ala Ala Glu Cys Thr Ile Phe Lys Asp Ala Ser Gly Lys 2915 2920 2925 Pro Val Pro Tyr Cys Tyr Asp Thr Asn Val Leu Glu Gly Ser Val 2930 2935 2940 Ala Tyr Glu Ser Leu Arg Pro Asp Thr Arg Tyr Val Leu Met Asp 2945 2950 2955 Gly Ser Ile Ile Gln Phe Pro Asn Thr Tyr Leu Glu Gly Ser Val 2960 2965 2970 Arg Val Val Thr Thr Phe Asp Ser Glu Tyr Cys Arg Hes Gly Thr 2975 2980 2985 Cys Glu Arg Ser Glu Ala Gly Val Cys Val Ser Thr Ser Gly Arg 2990 2995 3000 Trp Val Leu Asn Asn Asp Tyr Tyr Arg Ser Leu Pro Gly Val Phe 3005 3010 3015 Cys Gly Val Asp Ala Val Asn Leu Leu Thr Asn Met Phe Thr Pro 3020 3025 3030 Leu Ile Gln Pro Ile Gly Ala Leu Asp Ile Ser Ala Ser Ile Val 3035 3040 3045 Ala Gly Gly Ile Val Ala Ile Val Val Thr Cys Leu Ala Tyr Tyr 3050 3055 3060 Phe Met Arg Phe Arg Arg Ala Phe Gly Glu Tyr Ser Hes Val Val 3065 3070 3075 Ala Phe Asn Thr Leu Leu Phe Leu Met Ser Phe Thr Val Leu Cys 3080 3085 3090 Leu Thr Pro Val Tyr Ser Phe Leu Pro Gly Val Tyr Ser Val Ile 3095 3100 3105 Tyr Leu Tyr Leu Thr Phe Tyr Leu Thr Asn Asp Val Ser Phe Leu 3110 3115 3120 Ala Hes Ile Gln Trp Met Val Met Phe Thr Pro Leu Val Pro Phe 3125 3130 3135 Trp Ile Thr Ile Ala Tyr Ile Ile Cys Ile Ser Thr Lys Hes Phe 3140 3145 3150 Tyr Trp Phe Phe Ser Asn Tyr Leu Lys Arg Arg Val Val Phe Asn 3155 3160 3165 Gly Val Ser Phe Ser Thr Phe Glu Glu Ala Ala Leu Cys Thr Phe 3170 3175 3180 Leu Leu Asn Lys Glu Met Tyr Leu Lys Leu Arg Ser Asp Val Leu 3185 3190 3195 Leu Pro Leu Thr Gln Tyr Asn Arg Tyr Leu Ala Leu Tyr Asn Lys 3200 3205 3210 Tyr Lys Tyr Phe Ser Gly Ala Met Asp Thr Thr Ser Tyr Arg Glu 3215 3220 3225 Ala Ala Cys Cys Hes Leu Ala Lys Ala Leu Asn Asp Phe Ser Asn 3230 3235 3240 Ser Gly Ser Asp Val Leu Tyr Gln Pro Pro Gln Thr Ser Ile Thr 3245 3250 3255 Ser Ala Val Leu Gln Ser Gly Phe Arg Lys Met Ala Phe Pro Ser 3260 3265 3270 Gly Lys Val Glu Gly Cys Met Val Gln Val Thr Cys Gly Thr Thr 3275 3280 3285 Thr Leu Asn Gly Leu Trp Leu Asp Asp Val Val Tyr Cys Pro Arg 3290 3295 3300 Hes Val Ile Cys Thr Ser Glu Asp Met Leu Asn Pro Asn Tyr Glu 3305 3310 3315 Asp Leu Leu Ile Arg Lys Ser Asn Hes Asn Phe Leu Val Gln Ala 3320 3325 3330 Gly Asn Val Gln Leu Arg Val Ile Gly Hes Ser Met Gln Asn Cys 3335 3340 3345 Val Leu Lys Leu Lys Val Asp Thr Ala Asn Pro Lys Thr Pro Lys 3350 3355 3360 Tyr Lys Phe Val Arg Ile Gln Pro Gly Gln Thr Phe Ser Val Leu 3365 3370 3375 Ala Cys Tyr Asn Gly Ser Pro Ser Gly Val Tyr Gln Cys Ala Met 3380 3385 3390 Arg Pro Asn Phe Thr Ile Lys Gly Ser Phe Leu Asn Gly Ser Cys 3395 3400 3405 Gly Ser Val Gly Phe Asn Ile Asp Tyr Asp Cys Val Ser Phe Cys 3410 3415 3420 Tyr Met Hes Hes Met Glu Leu Pro Thr Gly Val Hes Ala Gly Thr 3425 3430 3435 Asp Leu Glu Gly Asn Phe Tyr Gly Pro Phe Val Asp Arg Gln Thr 3440 3445 3450 Ala Gln Ala Ala Gly Thr Asp Thr Thr Ile Thr Val Asn Val Leu 3455 3460 3465 Ala Trp Leu Tyr Ala Ala Val Ile Asn Gly Asp Arg Trp Phe Leu 3470 3475 3480 Asn Arg Phe Thr Thr Thr Leu Asn Asp Phe Asn Leu Val Ala Met 3485 3490 3495 Lys Tyr Asn Tyr Glu Pro Leu Thr Gln Asp Hes Val Asp Ile Leu 3500 3505 3510 Gly Pro Leu Ser Ala Gln Thr Gly Ile Ala Val Leu Asp Met Cys 3515 3520 3525 Ala Ser Leu Lys Glu Leu Leu Gln Asn Gly Met Asn Gly Arg Thr 3530 3535 3540 Ile Leu Gly Ser Ala Leu Leu Glu Asp Glu Phe Thr Pro Phe Asp 3545 3550 3555 Val Val Arg Gln Cys Ser Gly Val Thr Phe Gln Ser Ala Val Lys 3560 3565 3570 Arg Thr Ile Lys Gly Thr Hes Hes Trp Leu Leu Leu Thr Ile Leu 3575 3580 3585 Thr Ser Leu Leu Val Leu Val Gln Ser Thr Gln Trp Ser Leu Phe 3590 3595 3600 Phe Phe Leu Tyr Glu Asn Ala Phe Leu Pro Phe Ala Met Gly Ile 3605 3610 3615 Ile Ala Met Ser Ala Phe Ala Met Met Phe Val Lys Hes Lys Hes 3620 3625 3630 Ala Phe Leu Cys Leu Phe Leu Leu Pro Ser Leu Ala Thr Val Ala 3635 3640 3645 Tyr Phe Asn Met Val Tyr Met Pro Ala Ser Trp Val Met Arg Ile 3650 3655 3660 Met Thr Trp Leu Asp Met Val Asp Thr Ser Leu Ser Gly Phe Lys 3665 3670 3675 Leu Lys Asp Cys Val Met Tyr Ala Ser Ala Val Val Leu Leu Ile 3680 3685 3690 Leu Met Thr Ala Arg Thr Val Tyr Asp Asp Gly Ala Arg Arg Val 3695 3700 3705 Trp Thr Leu Met Asn Val Leu Thr Leu Val Tyr Lys Val Tyr Tyr 3710 3715 3720 Gly Asn Ala Leu Asp Gln Ala Ile Ser Met Trp Ala Leu Ile Ile 3725 3730 3735 Ser Val Thr Ser Asn Tyr Ser Gly Val Val Thr Thr Val Met Phe 3740 3745 3750 Leu Ala Arg Gly Ile Val Phe Met Cys Val Glu Tyr Cys Pro Ile 3755 3760 3765 Phe Phe Ile Thr Gly Asn Thr Leu Gln Cys Ile Met Leu Val Tyr 3770 3775 3780 Cys Phe Leu Gly Tyr Phe Cys Thr Cys Tyr Phe Gly Leu Phe Cys 3785 3790 3795 Leu Leu Asn Arg Tyr Phe Arg Leu Thr Leu Gly Val Tyr Asp Tyr 3800 3805 3810 Leu Val Ser Thr Gln Glu Phe Arg Tyr Met Asn Ser Gln Gly Leu 3815 3820 3825 Leu Pro Pro Lys Asn Ser Ile Asp Ala Phe Lys Leu Asn Ile Lys 3830 3835 3840 Leu Leu Gly Val Gly Gly Lys Pro Cys Ile Lys Val Ala Thr Val 3845 3850 3855 Gln Ser Lys Met Ser Asp Val Lys Cys Thr Ser Val Val Leu Leu 3860 3865 3870 Ser Val Leu Gln Gln Leu Arg Val Glu Ser Ser Ser Lys Leu Trp 3875 3880 3885 Ala Gln Cys Val Gln Leu Hes Asn Asp Ile Leu Leu Ala Lys Asp 3890 3895 3900 Thr Thr Glu Ala Phe Glu Lys Met Val Ser Leu Leu Ser Val Leu 3905 3910 3915 Leu Ser Met Gln Gly Ala Val Asp Ile Asn Lys Leu Cys Glu Glu 3920 3925 3930 Met Leu Asp Asn Arg Ala Thr Leu Gln Ala Ile Ala Ser Glu Phe 3935 3940 3945 Ser Ser Leu Pro Ser Tyr Ala Ala Phe Ala Thr Ala Gln Glu Ala 3950 3955 3960 Tyr Glu Gln Ala Val Ala Asn Gly Asp Ser Glu Val Val Leu Lys 3965 3970 3975 Lys Leu Lys Lys Ser Leu Asn Val Ala Lys Ser Glu Phe Asp Arg 3980 3985 3990 Asp Ala Ala Met Gln Arg Lys Leu Glu Lys Met Ala Asp Gln Ala 3995 4000 4005 Met Thr Gln Met Tyr Lys Gln Ala Arg Ser Glu Asp Lys Arg Ala 4010 4015 4020 Lys Val Thr Ser Ala Met Gln Thr Met Leu Phe Thr Met Leu Arg 4025 4030 4035 Lys Leu Asp Asn Asp Ala Leu Asn Asn Ile Ile Asn Asn Ala Arg 4040 4045 4050 Asp Gly Cys Val Pro Leu Asn Ile Ile Pro Leu Thr Thr Ala Ala 4055 4060 4065 Lys Leu Met Val Val Ile Pro Asp Tyr Asn Thr Tyr Lys Asn Thr 4070 4075 4080 Cys Asp Gly Thr Thr Phe Thr Tyr Ala Ser Ala Leu Trp Glu Ile 4085 4090 4095 Gln Gln Val Val Asp Ala Asp Ser Lys Ile Val Gln Leu Ser Glu 4100 4105 4110 Ile Ser Met Asp Asn Ser Pro Asn Leu Ala Trp Pro Leu Ile Val 4115 4120 4125 Thr Ala Leu Arg Ala Asn Ser Ala Val Lys Leu Gln Asn Asn Glu 4130 4135 4140 Leu Ser Pro Val Ala Leu Arg Gln Met Ser Cys Ala Ala Gly Thr 4145 4150 4155 Thr Gln Thr Ala Cys Thr Asp Asp Asn Ala Leu Ala Tyr Tyr Asn 4160 4165 4170 Thr Thr Lys Gly Gly Arg Phe Val Leu Ala Leu Leu Ser Asp Leu 4175 4180 4185 Gln Asp Leu Lys Trp Ala Arg Phe Pro Lys Ser Asp Gly Thr Gly 4190 4195 4200 Thr Ile Tyr Thr Glu Leu Glu Pro Pro Cys Arg Phe Val Thr Asp 4205 4210 4215 Thr Pro Lys Gly Pro Lys Val Lys Tyr Leu Tyr Phe Ile Lys Gly 4220 4225 4230 Leu Asn Asn Leu Asn Arg Gly Met Val Leu Gly Ser Leu Ala Ala 4235 4240 4245 Thr Val Arg Leu Gln Ala Gly Asn Ala Thr Glu Val Pro Ala Asn 4250 4255 4260 Ser Thr Val Leu Ser Phe Cys Ala Phe Ala Val Asp Ala Ala Lys 4265 4270 4275 Ala Tyr Lys Asp Tyr Leu Ala Ser Gly Gly Gln Pro Ile Thr Asn 4280 4285 4290 Cys Val Lys Met Leu Cys Thr Hes Thr Gly Thr Gly Gln Ala Ile 4295 4300 4305 Thr Val Thr Pro Glu Ala Asn Met Asp Gln Glu Ser Phe Gly Gly 4310 4315 4320 Ala Ser Cys Cys Leu Tyr Cys Arg Cys Hes Ile Asp Hes Pro Asn 4325 4330 4335 Pro Lys Gly Phe Cys Asp Leu Lys Gly Lys Tyr Val Gln Ile Pro 4340 4345 4350 Thr Thr Cys Ala Asn Asp Pro Val Gly Phe Thr Leu Lys Asn Thr 4355 4360 4365 Val Cys Thr Val Cys Gly Met Trp Lys Gly Tyr Gly Cys Ser Cys 4370 4375 4380 Asp Gln Leu Arg Glu Pro Met Leu Gln Ser Ala Asp Ala Gln Ser 4385 4390 4395 Phe Leu Asn Gly Phe Ala Val 4400 4405 <210> 14 <211> 1273 <212> PRT <213> SARS-CoV2 <400> 14 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ser Gln Cys Val 1 5 10 15 Asn Leu Thr Thr Arg Thr Gln Leu Pro Pro Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Hes Val Ser Gly Thr Asn Gly Thr Lys Arg Phe Asp 65 70 75 80 Asn Pro Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu 85 90 95 Lys Ser Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser 100 105 110 Lys Thr Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile 115 120 125 Lys Val Cys Glu Phe Gln Phe Cys Asn Asp Pro Phe Leu Gly Val Tyr 130 135 140 Tyr Hes Lys Asn Asn Lys Ser Trp Met Glu Ser Glu Phe Arg Val Tyr 145 150 155 160 Ser Ser Ala Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu 165 170 175 Met Asp Leu Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Arg Glu Phe 180 185 190 Val Phe Lys Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr 195 200 205 Pro Ile Asn Leu Val Arg Asp Leu Pro Gln Gly Phe Ser Ala Leu Glu 210 215 220 Pro Leu Val Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Thr 225 230 235 240 Leu Leu Ala Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser 245 250 255 Gly Trp Thr Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro 260 265 270 Arg Thr Phe Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala 275 280 285 Val Asp Cys Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys 290 295 300 Ser Phe Thr Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Val 305 310 315 320 Gln Pro Thr Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys 325 330 335 Pro Phe Gly Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala 340 345 350 Trp Asn Arg Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Phe Leu 355 360 365 Tyr Asn Ser Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro 370 375 380 Thr Lys Leu Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe 385 390 395 400 Val Ile Arg Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly 405 410 415 Lys Ile Ala Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys 420 425 430 Val Ile Ala Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn 435 440 445 Tyr Asn Tyr Leu Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe 450 455 460 Glu Arg Asp Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys 465 470 475 480 Asn Gly Val Glu Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly 485 490 495 Phe Gln Pro Thr Asn Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val 500 505 510 Leu Ser Phe Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys 515 520 525 Lys Ser Thr Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn 530 535 540 Gly Leu Thr Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu 545 550 555 560 Pro Phe Gln Gln Phe Gly Arg Asp Ile Ala Asp Thr Thr Asp Ala Val 565 570 575 Arg Asp Pro Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe 580 585 590 Gly Gly Val Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val 595 600 605 Ala Val Leu Tyr Gln Asp Val Asn Cys Thr Glu Val Pro Val Ala Ile 610 615 620 Hes Ala Asp Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser 625 630 635 640 Asn Val Phe Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Hes Val 645 650 655 Asn Asn Ser Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala 660 665 670 Ser Tyr Gln Thr Gln Thr Asn Ser Pro Arg Arg Ala Arg Ser Val Ala 675 680 685 Ser Gln Ser Ile Ile Ala Tyr Thr Met Ser Leu Gly Ala Glu Asn Ser 690 695 700 Val Ala Tyr Ser Asn Asn Ser Ile Ala Ile Pro Thr Asn Phe Thr Ile 705 710 715 720 Ser Val Thr Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val 725 730 735 Asp Cys Thr Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu 740 745 750 Leu Leu Gln Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr 755 760 765 Gly Ile Ala Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln 770 775 780 Val Lys Gln Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe 785 790 795 800 Asn Phe Ser Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser 805 810 815 Phe Ile Glu Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly 820 825 830 Phe Ile Lys Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp 835 840 845 Leu Ile Cys Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu 850 855 860 Leu Thr Asp Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly 865 870 875 880 Thr Ile Thr Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile 885 890 895 Pro Phe Ala Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr 900 905 910 Gln Asn Val Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn 915 920 925 Ser Ala Ile Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala 930 935 940 Leu Gly Lys Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn 945 950 955 960 Thr Leu Val Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val 965 970 975 Leu Asn Asp Ile Leu Ser Arg Leu Asp Lys Val Glu Ala Glu Val Gln 980 985 990 Ile Asp Arg Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val 995 1000 1005 Thr Gln Gln Leu Ile Arg Ala Ala Glu Ile Arg Ala Ser Ala Asn 1010 1015 1020 Leu Ala Ala Thr Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys 1025 1030 1035 Arg Val Asp Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro 1040 1045 1050 Gln Ser Ala Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val 1055 1060 1065 Pro Ala Gln Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes 1070 1075 1080 Asp Gly Lys Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn 1085 1090 1095 Gly Thr Hes Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln 1100 1105 1110 Ile Ile Thr Thr Asp Asn Thr Phe Val Ser Gly Asn Cys Asp Val 1115 1120 1125 Val Ile Gly Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro 1130 1135 1140 Glu Leu Asp Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn 1145 1150 1155 Hes Thr Ser Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn 1160 1165 1170 Ala Ser Val Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu 1175 1180 1185 Val Ala Lys Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu 1190 1195 1200 Gly Lys Tyr Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu 1205 1210 1215 Gly Phe Ile Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met 1220 1225 1230 Leu Cys Cys Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys 1235 1240 1245 Ser Cys Gly Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro 1250 1255 1260 Val Leu Lys Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 15 <211> 29885 <212> ADN <213> SARS-CoV2 <220> <221> diferentes_características <222> (1)..(30) <223> n es a, c, g, ó t <220> <221> diferentes_características <222> (29865)..(29865) <223> n es a, c, g, ó t <220> <221> diferentes_características <222> (29872)..(29885) <223> n es a, c, g, ó t <400> 15 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn accaaccaac tttcgatctc ttgtagatct 60 gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact 120 cacgcagtat aattaataac taattactgt cgttgacagg acacgagtaa ctcgtctatc 180 ttctgcaggc tgcttacggt ttcgtccgtg ttgcagccga tcatcagcac atctaggttt 240 tgtccgggtg tgaccgaaag gtaagatgga gagccttgtc cctggtttca acgagaaaac 300 acacgtccaa ctcagtttgc ctgttttaca ggttcgcgac gtgctcgtac gtggctttgg 360 agactccgtg gaggaggtct tatcagaggc acgtcaacat cttaaagatg gcacttgtgg 420 cttagtagaa gttgaaaaag gcgttttgcc tcaacttgaa cagccctatg tgttcatcaa 480 acgttcggat gctcgaactg cacctcatgg tcatgttatg gttgagctgg tagcagaact 540 cgaaggcatt cagtacggtc gtagtggtga gacacttggt gtccttgtcc ctcatgtggg 600 cgaaatacca gtggcttacc gcaaggttct tcttcgtaag aacggtaata aaggagctgg 660 tggccatagt tacggcgccg atctaaagtc atttgactta ggcgacgagc ttggcactga 720 tccttatgaa gattttcaag aaaactggaa cactaaacat agcagtggtg ttacccgtga 780 actcatgcgt gagcttaacg gaggggcata cactcgctat gtcgataaca acttctgtgg 840 ccctgatggc taccctcttg agtgcattaa agaccttcta gcacgtgctg gtaaagcttc 900 atgcactttg tccgaacaac tggactttat tgacactaag aggggtgtat actgctgccg 960 tgaacatgag catgaaattg cttggtacac ggaacgttct gaaaagagct atgaattgca 1020 gacacctttt gaaattaaat tggcaaagaa atttgacacc ttcaatgggg aatgtccaaa 1080 ttttgtattt cccttaaatt ccataatcaa gactattcaa ccaagggttg aaaagaaaaa 1140 gcttgatggc tttatgggta gaattcgatc tgtctatcca gttgcgtcac caaatgaatg 1200 caaccaaatg tgcctttcaa ctctcatgaa gtgtgatcat tgtggtgaaa cttcatggca 1260 gacgggcgat tttgttaaag ccacttgcga attttgtggc actgagaatt tgactaaaga 1320 aggtgccact acttgtggtt acttacccca aaatgctgtt gttaaaattt attgtccagc 1380 atgtcacaat tcagaagtag gacctgagca tagtcttgcc gaataccata atgaatctgg 1440 cttgaaaacc attcttcgta agggtggtcg cactattgcc tttggaggct gtgtgttctc 1500 ttatgttggt tgccataaca agtgtgccta ttgggttcca cgtgctagcg ctaacatagg 1560 ttgtaaccat acaggtgttg ttggagaagg ttccgaaggt cttaatgaca accttcttga 1620 aatactccaa aaagagaaag tcaacatcaa tattgttggt gactttaaac ttaatgaaga 1680 gatcgccatt attttggcat ctttttctgc ttccacaagt gcttttgtgg aaactgtgaa 1740 aggtttggat tataaagcat tcaaacaaat tgttgaatcc tgtggtaatt ttaaagttac 1800 aaaaggaaaa gctaaaaaag gtgcctggaa tattggtgaa cagaaatcaa tactgagtcc 1860 tctttatgca tttgcatcag aggctgctcg tgttgtacga tcaattttct cccgcactct 1920 tgaaactgct caaaattctg tgcgtgtttt acagaaggcc gctataacaa tactagatgg 1980 aatttcacag tattcactga gactcattga tgctatgatg ttcacatctg atttggctac 2040 taacaatcta gttgtaatgg cctacattac aggtggtgtt gttcagttga cttcgcagtg 2100 gctaactaac atctttggca ctgtttatga aaaactcaaa cccgtccttg attggcttga 2160 agagaagttt aaggaaggtg tagagtttct tagagacggt tgggaaattg ttaaatttat 2220 ctcaacctgt gcttgtgaaa ttgtcggtgg acaaattgtc acctgtgcaa aggaaattaa 2280 ggagagtgtt cagacattct ttaagcttgt aaataaattt ttggctttgt gtgctgactc 2340 tatcattatt ggtggagcta aacttaaagc cttgaattta ggtgaaacat ttgtcacgca 2400 ctcaaaggga ttgtacagaa agtgtgttaa atccagagaa gaaactggcc tactcatgcc 2460 tctaaaagcc ccaaaagaaa ttatcttctt agagggagaa acacttccca cagaagtgtt 2520 aacagaggaa gttgtcttga aaactggtga tttacaacca ttagaacaac ctactagtga 2580 agctgttgaa gctccattgg ttggtacacc agtttgtatt aacgggctta tgttgctcga 2640 aatcaaagac acagaaaagt actgtgccct tgcacctaat atgatggtaa caaacaatac 2700 cttcacactc aaaggcggtg caccaacaaa ggttactttt ggtgatgaca ctgtgataga 2760 agtgcaaggt tacaagagtg tgaatatcac ttttgaactt gatgaaagga ttgataaagt 2820 acttaatgag aagtgctctg cctatacagt tgaactcggt acagaagtaa atgagttcgc 2880 ctgtgttgtg gcagatgctg tcataaaaac tttgcaacca gtatctgaat tacttacacc 2940 actgggcatt gatttagatg agtggagtat ggctacatac tacttatttg atgagtctgg 3000 tgagtttaaa ttggcttcac atatgtattg ttctttttac cctccagatg aggatgaaga 3060 agaaggtgat tgtgaagaag aagagtttga gccatcaact caatatgagt atggtactga 3120 agatgattac caaggtaaac ctttggaatt tggtgccact tctgctgctc ttcaacctga 3180 agaagagcaa gaagaagatt ggttagatga tgatagtcaa caaactgttg gtcaacaaga 3240 cggcagtgag gacaatcaga caactactat tcaaacaatt gttgaggttc aacctcaatt 3300 agagatggaa cttacaccag ttgttcagac tattgaagtg aatagtttta gtggttattt 3360 aaaacttact gacaatgtat acattaaaaa tgcagacatt gtggaagaag ctaaaaaggt 3420 aaaaccaaca gtggttgtta atgcagccaa tgtttacctt aaacatggag gaggtgttgc 3480 aggagcctta aataaggcta ctaacaatgc catgcaagtt gaatctgatg attacatagc 3540 tactaatgga ccacttaaag tgggtggtag ttgtgtttta agcggacaca atcttgctaa 3600 acactgtctt catgttgtcg gcccaaatgt taacaaaggt gaagacattc aacttcttaa 3660 gagtgcttat gaaaatttta atcagcacga agttctactt gcaccattat tatcagctgg 3720 tatttttggt gctgacccta tacattcttt aagagtttgt gtagatactg ttcgcacaaa 3780 tgtctactta gctgtctttg ataaaaatct ctatgacaaa cttgtttcaa gctttttgga 3840 aatgaagagt gaaaagcaag ttgaacaaaa gatcgctgag attcctaaag aggaagttaa 3900 gccatttata actgaaagta aaccttcagt tgaacagaga aaacaagatg ataagaaaat 3960 caaagcttgt gttgaagaag ttacaacaac tctggaagaa actaagttcc tcacagaaaa 4020 cttgttactt tatattgaca ttaatggcaa tcttcatcca gattctgcca ctcttgttag 4080 tgacattgac atcactttct taaagaaaga tgctccatat atagtgggtg atgttgttca 4140 agagggtgtt ttaactgctg tggttatacc tactaaaaag gctggtggca ctactgaaat 4200 gctagcgaaa gctttgagaa aagtgccaac agacaattat ataaccactt acccgggtca 4260 gggtttaaat ggttacactg tagaggaggc aaagacagtg cttaaaaagt gtaaaagtgc 4320 cttttacatt ctaccatcta ttatctctaa tgagaagcaa gaaattcttg gaactgtttc 4380 ttggaatttg cgagaaatgc ttgcacatgc agaagaaaca cgcaaattaa tgcctgtctg 4440 tgtggaaact aaagccatag tttcaactat acagcgtaaa tataagggta ttaaaataca 4500 agagggtgtg gttgattatg gtgctagatt ttacttttac accagtaaaa caactgtagc 4560 gtcacttatc aacacactta acgatctaaa tgaaactctt gttacaatgc cacttggcta 4620 tgtaacacat ggcttaaatt tggaagaagc tgctcggtat atgagatctc tcaaagtgcc 4680 agctacagtt tctgtttctt cacctgatgc tgttacagcg tataatggtt atcttacttc 4740 ttcttctaaa acacctgaag aacattttat tgaaaccatc tcacttgctg gttcctataa 4800 agattggtcc tattctggac aatctacaca actaggtata gaatttctta agagaggtga 4860 taaaagtgta tattacacta gtaatcctac cacattccac ctagatggtg aagttatcac 4920 ctttgacaat cttaagacac ttctttcttt gagagaagtg aggactatta aggtgtttac 4980 aacagtagac aacattaacc tccacacgca agttgtggac atgtcaatga catatggaca 5040 acagtttggt ccaacttatt tggatggagc tgatgttact aaaataaaac ctcataattc 5100 acatgaaggt aaaacatttt atgttttacc taatgatgac actctacgtg ttgaggcttt 5160 tgagtactac cacacaactg atcctagttt tctgggtagg tacatgtcag cattaaatca 5220 cactaaaaag tggaaatacc cacaagttaa tggtttaact tctattaaat gggcagataa 5280 caactgttat cttgccactg cattgttaac actccaacaa atagagttga agtttaatcc 5340 acctgctcta caagatgctt attacagagc aagggctggt gaagctgcta acttttgtgc 5400 acttatctta gcctactgta ataagacagt aggtgagtta ggtgatgtta gagaaacaat 5460 gagttacttg tttcaacatg ccaatttaga ttcttgcaaa agagtcttga acgtggtgtg 5520 taaaacttgt ggacaacagc agacaaccct taagggtgta gaagctgtta tgtacatggg 5580 cacactttct tatgaacaat ttaagaaagg tgttcagata ccttgtacgt gtggtaaaca 5640 agctacaaaa tatctagtac aacaggagtc accttttgtt atgatgtcag caccacctgc 5700 tcagtatgaa cttaagcatg gtacatttac ttgtgctagt gagtacactg gtaattacca 5760 gtgtggtcac tataaacata taacttctaa agaaactttg tattgcatag acggtgcttt 5820 acttacaaag tcctcagaat acaaaggtcc tattacggat gttttctaca aagaaaacag 5880 ttacacaaca accataaaac cagttactta taaattggat ggtgttgttt gtacagaaat 5940 tgaccctaag ttggacaatt attataagaa agacaattct tatttcacag agcaaccaat 6000 tgatcttgta ccaaaccaac catatccaaa cgcaagcttc gataatttta agtttgtatg 6060 tgataatatc aaatttgctg atgatttaaa ccagttaact ggttataaga aacctgcttc 6120 aagagagctt aaagttacat ttttccctga cttaaatggt gatgtggtgg ctattgatta 6180 taaacactac acaccctctt ttaagaaagg agctaaattg ttacataaac ctattgtttg 6240 gcatgttaac aatgcaacta ataaagccac gtataaacca aatacctggt gtatacgttg 6300 tctttggagc acaaaaccag ttgaaacatc aaattcgttt gatgtactga agtcagagga 6360 cgcgcaggga atggataatc ttgcctgcga agatctaaaa ccagtctctg aagaagtagt 6420 ggaaaatcct accatacaga aagacgttct tgagtgtaat gtgaaaacta ccgaagttgt 6480 aggagacatt atacttaaac cagcaaataa tagtttaaaa attacagaag aggttggcca 6540 cacagatcta atggctgctt atgtagacaa ttctagtctt actattaaga aacctaatga 6600 attatctaga gtattaggtt tgaaaaccct tgctactcat ggtttagctg ctgttaatag 6660 tgtcccttgg gatactatag ctaattatgc taagcctttt cttaacaaag ttgttagtac 6720 aactactaac atagttacac ggtgtttaaa ccgtgtttgt actaattata tgccttattt 6780 ctttacttta ttgctacaat tgtgtacttt tactagaagt acaaattcta gaattaaagc 6840 atctatgccg actactatag caaagaatac tgttaagagt gtcggtaaat tttgtctaga 6900 ggcttcattt aattatttga agtcacctaa tttttctaaa ctgataaata ttataatttg 6960 gtttttacta ttaagtgttt gcctaggttc tttaatctac tcaaccgctg ctttaggtgt 7020 tttaatgtct aatttaggca tgccttctta ctgtactggt tacagagaag gctatttgaa 7080 ctctactaat gtcactattg caacctactg tactggttct ataccttgta gtgtttgtct 7140 tagtggttta gattctttag acacctatcc ttctttagaa actatacaaa ttaccatttc 7200 atcttttaaa tgggatttaa ctgcttttgg cttagttgca gagtggtttt tggcatatat 7260 tcttttcact aggtttttct atgtacttgg attggctgca atcatgcaat tgtttttcag 7320 ctattttgca gtacatttta ttagtaattc ttggcttatg tggttaataa ttaatcttgt 7380 acaaatggcc ccgatttcag ctatggttag aatgtacatc ttctttgcat cattttatta 7440 tgtatggaaa agttatgtgc atgttgtaga cggttgtaat tcatcaactt gtatgatgtg 7500 ttacaaacgt aatagagcaa caagagtcga atgtacaact attgttaatg gtgttagaag 7560 gtccttttat gtctatgcta atggaggtaa aggcttttgc aaactacaca attggaattg 7620 tgttaattgt gatacattct gtgctggtag tacatttatt agtgatgaag ttgcgagaga 7680 cttgtcacta cagtttaaaa gaccaataaa tcctactgac cagtcttctt acatcgttga 7740 tagtgttaca gtgaagaatg gttccatcca tctttacttt gataaagctg gtcaaaagac 7800 ttatgaaaga cattctctct ctcattttgt taacttagac aacctgagag ctaataacac 7860 taaaggttca ttgcctatta atgttatagt ttttgatggt aaatcaaaat gtgaagaatc 7920 atctgcaaaa tcagcgtctg tttactacag tcagcttatg tgtcaaccta tactgttact 7980 agatcaggca ttagtgtctg atgttggtga tagtgcggaa gttgcagtta aaatgtttga 8040 tgcttacgtt aatacgtttt catcaacttt taacgtacca atggaaaaac tcaaaacact 8100 agttgcaact gcagaagctg aacttgcaaa gaatgtgtcc ttagacaatg tcttatctac 8160 ttttatttca gcagctcggc aagggtttgt tgattcagat gtagaaacta aagatgttgt 8220 tgaatgtctt aaattgtcac atcaatctga catagaagtt actggcgata gttgtaataa 8280 ctatatgctc acctataaca aagttgaaaa catgacaccc cgtgaccttg gtgcttgtat 8340 tgactgtagt gcgcgtcata ttaatgcgca ggtagcaaaa agtcacaaca ttgctttgat 8400 atggaacgtt aaagatttca tgtcattgtc tgaacaacta cgaaaacaaa tacgtagtgc 8460 tgctaaaaag aataacttac cttttaagtt gacatgtgca actactagac aagttgttaa 8520 tgttgtaaca acaaagatag cacttaaggg tggtaaaatt gttaataatt ggttgaagca 8580 gttaattaaa gttacacttg tgttcctttt tgttgctgct attttctatt taataacacc 8640 tgttcatgtc atgtctaaac atactgactt ttcaagtgaa atcataggat acaaggctat 8700 tgatggtggt gtcactcgtg acatagcatc tacagatact tgttttgcta acaaacatgc 8760 tgattttgac acatggttta gccagcgtgg tggtagttat actaatgaca aagcttgccc 8820 attgattgct gcagtcataa caagagaagt gggttttgtc gtgcctggtt tgcctggcac 8880 gatattacgc acaactaatg gtgacttttt gcatttctta cctagagttt ttagtgcagt 8940 tggtaacatc tgttacacac catcaaaact tatagagtac actgactttg caacatcagc 9000 ttgtgttttg gctgctgaat gtacaatttt taaagatgct tctggtaagc cagtaccata 9060 ttgttatgat accaatgtac tagaaggttc tgttgcttat gaaagtttac gccctgacac 9120 acgttatgtg ctcatggatg gctctattat tcaatttcct aacacctacc ttgaaggttc 9180 tgttagagtg gtaacaactt ttgattctga gtactgtagg cacggcactt gtgaaagatc 9240 agaagctggt gtttgtgtat ctactagtgg tagatgggta cttaacaatg attattacag 9300 atctttacca ggagttttct gtggtgtaga tgctgtaaat ttacttacta atatgtttac 9360 accactaatt caacctattg gtgctttgga catatcagca tctatagtag ctggtggtat 9420 tgtagctatc gtagtaacat gccttgccta ctattttatg aggtttagaa gagcttttgg 9480 tgaatacagt catgtagttg cctttaatac tttactattc cttatgtcat tcactgtact 9540 ctgtttaaca ccagtttact cattcttacc tggtgtttat tctgttattt acttgtactt 9600 gacattttat cttactaatg atgtttcttt tttagcacat attcagtgga tggttatgtt 9660 cacaccttta gtacctttct ggataacaat tgcttatatc atttgtattt ccacaaagca 9720 tttctattgg ttctttagta attacctaaa gagacgtgta gtctttaatg gtgtttcctt 9780 tagtactttt gaagaagctg cgctgtgcac ctttttgtta aataaagaaa tgtatctaaa 9840 gttgcgtagt gatgtgctat tacctcttac gcaatataat agatacttag ctctttataa 9900 taagtacaag tattttagtg gagcaatgga tacaactagc tacagagaag ctgcttgttg 9960 tcatctcgca aaggctctca atgacttcag taactcaggt tctgatgttc tttaccaacc 10020 accacaaacc tctatcacct cagctgtttt gcagagtggt tttagaaaaa tggcattccc 10080 atctggtaaa gttgagggtt gtatggtaca agtaacttgt ggtacaacta cacttaacgg 10140 tctttggctt gatgacgtag tttactgtcc aagacatgtg atctgcacct ctgaagacat 10200 gcttaaccct aattatgaag atttactcat tcgtaagtct aatcataatt tcttggtaca 10260 ggctggtaat gttcaactca gggttattgg acattctatg caaaattgtg tacttaagct 10320 taaggttgat acagccaatc ctaagacacc taagtataag tttgttcgca ttcaaccagg 10380 acagactttt tcagtgttag cttgttacaa tggttcacca tctggtgttt accaatgtgc 10440 tatgaggccc aatttcacta ttaagggttc attccttaat ggttcatgtg gtagtgttgg 10500 ttttaacata gattatgact gtgtctcttt ttgttacatg caccatatgg aattaccaac 10560 tggagttcat gctggcacag acttagaagg taacttttat ggaccttttg ttgacaggca 10620 aacagcacaa gcagctggta cggacacaac tattacagtt aatgttttag cttggttgta 10680 cgctgctgtt ataaatggag acaggtggtt tctcaatcga tttaccacaa ctcttaatga 10740 ctttaacctt gtggctatga agtacaatta tgaacctcta acacaagacc atgttgacat 10800 actaggacct ctttctgctc aaactggaat tgccgtttta gatatgtgtg cttcattaaa 10860 agaattactg caaaatggta tgaatggacg taccatattg ggtagtgctt tattagaaga 10920 tgaatttaca ccttttgatg ttgttagaca atgctcaggt gttactttcc aaagtgcagt 10980 gaaaagaaca atcaagggta cacaccactg gttgttactc acaattttga cttcactttt 11040 agttttagtc cagagtactc aatggtcttt gttctttttt ttgtatgaaa atgccttttt 11100 accttttgct atgggtatta ttgctatgtc tgcttttgca atgatgtttg tcaaacataa 11160 gcatgcattt ctctgtttgt ttttgttacc ttctcttgcc actgtagctt attttaatat 11220 ggtctatatg cctgctagtt gggtgatgcg tattatgaca tggttggata tggttgatac 11280 tagtttgtct ggttttaagc taaaagactg tgttatgtat gcatcagctg tagtgttact 11340 aatccttatg acagcaagaa ctgtgtatga tgatggtgct aggagagtgt ggacacttat 11400 gaatgtcttg acactcgttt ataaagttta ttatggtaat gctttagatc aagccatttc 11460 catgtgggct cttataatct ctgttacttc taactactca ggtgtagtta caactgtcat 11520 gtttttggcc agaggtattg tttttatgtg tgttgagtat tgccctattt tcttcataac 11580 tggtaataca cttcagtgta taatgctagt ttattgtttc ttaggctatt tttgtacttg 11640 ttactttggc ctcttttgtt tactcaaccg ctactttaga ctgactcttg gtgtttatga 11700 ttacttagtt tctacacagg agtttagata tatgaattca cagggactac tcccacccaa 11760 gaatagcata gatgccttca aactcaacat taaattgttg ggtgttggtg gcaaaccttg 11820 tatcaaagta gccactgtac agtctaaaat gtcagatgta aagtgcacat cagtagtctt 11880 actctcagtt ttgcaacaac tcagagtaga atcatcatct aaattgtggg ctcaatgtgt 11940 ccagttacac aatgacattc tcttagctaa agatactact gaagcctttg aaaaaatggt 12000 ttcactactt tctgttttgc tttccatgca gggtgctgta gacataaaca agctttgtga 12060 agaaatgctg gacaacaggg caaccttaca agctatagcc tcagagttta gttcccttcc 12120 atcatatgca gcttttgcta ctgctcaaga agcttatgag caggctgttg ctaatggtga 12180 ttctgaagtt gttcttaaaa agttgaagaa gtctttgaat gtggctaaat ctgaatttga 12240 ccgtgatgca gccatgcaac gtaagttgga aaagatggct gatcaagcta tgacccaaat 12300 gtataaacag gctagatctg aggacaagag ggcaaaagtt actagtgcta tgcagacaat 12360 gcttttcact atgcttagaa agttggataa tgatgcactc aacaacatta tcaacaatgc 12420 aagagatggt tgtgttccct tgaacataat acctcttaca acagcagcca aactaatggt 12480 tgtcatacca gactataaca catataaaaa tacgtgtgat ggtacaacat ttacttatgc 12540 atcagcattg tgggaaatcc aacaggttgt agatgcagat agtaaaattg ttcaacttag 12600 tgaaattagt atggacaatt cacctaattt agcatggcct cttattgtaa cagctttaag 12660 ggccaattct gctgtcaaat tacagaataa tgagcttagt cctgttgcac tacgacagat 12720 gtcttgtgct gccggtacta cacaaactgc ttgcactgat gacaatgcgt tagcttacta 12780 caacacaaca aagggaggta ggtttgtact tgcactgtta tccgatttac aggatttgaa 12840 atgggctaga ttccctaaga gtgatggaac tggtactatc tatacagaac tggaaccacc 12900 ttgtaggttt gttacagaca cacctaaagg tcctaaagtg aagtatttat actttattaa 12960 aggattaaac aacctaaata gaggtatggt acttggtagt ttagctgcca cagtacgtct 13020 acaagctggt aatgcaacag aagtgcctgc caattcaact gtattatctt tctgtgcttt 13080 tgctgtagat gctgctaaag cttacaaaga ttatctagct agtgggggac aaccaatcac 13140 taattgtgtt aagatgttgt gtacacacac tggtactggt caggcaataa cagttacacc 13200 ggaagccaat atggatcaag aatcctttgg tggtgcatcg tgttgtctgt actgccgttg 13260 ccacatagat catccaaatc ctaaaggatt ttgtgactta aaaggtaagt atgtacaaat 13320 acctacaact tgtgctaatg accctgtggg ttttacactt aaaaacacag tctgtaccgt 13380 ctgcggtatg tggaaaggtt atggctgtag ttgtgatcaa ctccgcgaac ccatgcttca 13440 gtcagctgat gcacaatcgt ttttaaacgg gtttgcggtg taagtgcagc ccgtcttaca 13500 ccgtgcggca caggcactag tactgatgtc gtatacaggg cttttgacat ctacaatgat 13560 aaagtagctg gttttgctaa attcctaaaa actaattgtt gtcgcttcca agaaaaggac 13620 gaagatgaca atttaattga ttcttacttt gtagttaaga gacacacttt ctctaactac 13680 caacatgaag aaacaattta taatttactt aaggattgtc cagctgttgc taaacatgac 13740 ttctttaagt ttagaataga cggtgacatg gtaccacata tatcacgtca acgtcttact 13800 aaatacacaa tggcagacct cgtctatgct ttaaggcatt ttgatgaagg taattgtgac 13860 acattaaaag aaatacttgt cacatacaat tgttgtgatg atgattattt caataaaaag 13920 gactggtatg attttgtaga aaacccagat atattacgcg tatacgccaa cttaggtgaa 13980 cgtgtacgcc aagctttgtt aaaaacagta caattctgtg atgccatgcg aaatgctggt 14040 attgttggtg tactgacatt agataatcaa gatctcaatg gtaactggta tgatttcggt 14100 gatttcatac aaaccacgcc aggtagtgga gttcctgttg tagattctta ttattcattg 14160 ttaatgccta tattaacctt gaccagggct ttaactgcag agtcacatgt tgacactgac 14220 ttaacaaagc cttacattaa gtgggatttg ttaaaatatg acttcacgga agagaggtta 14280 aaactctttg accgttattt taaatattgg gatcagacat accacccaaa ttgtgttaac 14340 tgtttggatg acagatgcat tctgcattgt gcaaacttta atgttttatt ctctacagtg 14400 ttcccactta caagttttgg accactagtg agaaaaatat ttgttgatgg tgttccattt 14460 gtagtttcaa ctggatacca cttcagagag ctaggtgttg tacataatca ggatgtaaac 14520 ttacatagct ctagacttag ttttaaggaa ttacttgtgt atgctgctga ccctgctatg 14580 cacgctgctt ctggtaatct attactagat aaacgcacta cgtgcttttc agtagctgca 14640 cttactaaca atgttgcttt tcaaactgtc aaacccggta attttaacaa agacttctat 14700 gactttgctg tgtctaaggg tttctttaag gaaggaagtt ctgttgaatt aaaacacttc 14760 ttctttgctc aggatggtaa tgctgctatc agcgattatg actactatcg ttataatcta 14820 ccaacaatgt gtgatatcag acaactacta tttgtagttg aagttgttga taagtacttt 14880 gattgttacg atggtggctg tattaatgct aaccaagtca tcgtcaacaa cctagacaaa 14940 tcagctggtt ttccatttaa taaatggggt aaggctagac tttattatga ttcaatgagt 15000 tatgaggatc aagatgcact tttcgcatat acaaaacgta atgtcatccc tactataact 15060 caaatgaatc ttaagtatgc cattagtgca aagaatagag ctcgcaccgt agctggtgtc 15120 tctatctgta gtactatgac caatagacag tttcatcaaa aattattgaa atcaatagcc 15180 gccactagag gagctactgt agtaattgga acaagcaaat tctatggtgg ttggcacaac 15240 atgttaaaaa ctgtttatag tgatgtagaa aaccctcacc ttatgggttg ggattatcct 15300 aaatgtgata gagccatgcc taacatgctt agaattatgg cctcacttgt tcttgctcgc 15360 aaacatacaa cgtgttgtag cttgtcacac cgtttctata gattagctaa tgagtgtgct 15420 caagtattga gtgaaatggt catgtgtggc ggttcactat atgttaaacc aggtggaacc 15480 tcatcaggag atgccacaac tgcttatgct aatagtgttt ttaacatttg tcaagctgtc 15540 acggccaatg ttaatgcact tttatctact gatggtaaca aaattgccga taagtatgtc 15600 cgcaatttac aacacagact ttatgagtgt ctctatagaa atagagatgt tgacacagac 15660 tttgtgaatg agttttacgc atatttgcgt aaacatttct caatgatgat actctctgac 15720 gatgctgttg tgtgtttcaa tagcacttat gcatctcaag gtctagtggc tagcataaag 15780 aactttaagt cagttcttta ttatcaaaac aatgttttta tgtctgaagc aaaatgttgg 15840 actgagactg accttactaa aggacctcat gaattttgct ctcaacatac aatgctagtt 15900 aaacagggtg atgattatgt gtaccttcct tacccagatc catcaagaat cctaggggcc 15960 ggctgttttg tagatgatat cgtaaaaaca gatggtacac ttatgattga acggttcgtg 16020 tctttagcta tagatgctta cccacttact aaacatccta atcaggagta tgctgatgtc 16080 tttcatttgt acttacaata cataagaaag ctacatgatg agttaacagg acacatgtta 16140 gacatgtatt ctgttatgct tactaatgat aacacttcaa ggtattggga acctgagttt 16200 tatgaggcta tgtacacacc gcatacagtc ttacaggctg ttggggcttg tgttctttgc 16260 aattcacaga cttcattaag atgtggtgct tgcatacgta gaccattctt atgttgtaaa 16320 tgctgttacg accatgtcat atcaacatca cataaattag tcttgtctgt taatccgtat 16380 gtttgcaatg ctccaggttg tgatgtcaca gatgtgactc aactttactt aggaggtatg 16440 agctattatt gtaaatcaca taaaccaccc attagttttc cattgtgtgc taatggacaa 16500 gtttttggtt tatataaaaa tacatgtgtt ggtagcgata atgttactga ctttaatgca 16560 attgcaacat gtgactggac aaatgctggt gattacattt tagctaacac ctgtactgaa 16620 agactcaagc tttttgcagc agaaacgctc aaagctactg aggagacatt taaactgtct 16680 tatggtattg ctactgtacg tgaagtgctg tctgacagag aattacatct ttcatgggaa 16740 gttggtaaac ctagaccacc acttaaccga aattatgtct ttactggtta tcgtgtaact 16800 aaaaacagta aagtacaaat aggagagtac acctttgaaa aaggtgacta tggtgatgct 16860 gttgtttacc gaggtacaac aacttacaaa ttaaatgttg gtgattattt tgtgctgaca 16920 tcacatacag taatgccatt aagtgcacct acactagtgc cacaagagca ctatgttaga 16980 attactggct tatacccaac actcaatatc tcagatgagt tttctagcaa tgttgcaaat 17040 tatcaaaagg ttggtatgca aaagtattct acactccagg gaccacctgg tactggtaag 17100 agtcattttg ctattggcct agctctctac tacccttctg ctcgcatagt gtatacagct 17160 tgctctcatg ccgctgttga tgcactatgt gagaaggcat taaaatattt gcctatagat 17220 aaatgtagta gaattatacc tgcacgtgct cgtgtagagt gttttgataa attcaaagtg 17280 aattcaacat tagaacagta tgtcttttgt actgtaaatg cattgcctga gacgacagca 17340 gatatagttg tctttgatga aatttcaatg gccacaaatt atgatttgag tgttgtcaat 17400 gccagattac gtgctaagca ctatgtgtac attggcgacc ctgctcaatt acctgcacca 17460 cgcacattgc taactaaggg cacactagaa ccagaatatt tcaattcagt gtgtagactt 17520 atgaaaacta taggtccaga catgttcctc ggaacttgtc ggcgttgtcc tgctgaaatt 17580 gttgacactg tgagtgcttt ggtttatgat aataagctta aagcacataa agacaaatca 17640 gctcaatgct ttaaaatgtt ttataagggt gttatcacgc atgatgtttc atctgcaatt 17700 aacaggccac aaataggcgt ggtaagagaa ttccttacac gtaaccctgc ttggagaaaa 17760 gctgtcttta tttcacctta taattcacag aatgctgtag cctcaaagat tttgggacta 17820 ccaactcaaa ctgttgattc atcacagggc tcagaatatg actatgtcat attcactcaa 17880 accactgaaa cagctcactc ttgtaatgta aacagattta atgttgctat taccagagca 17940 aaagtaggca tactttgcat aatgtctgat agagaccttt atgacaagtt gcaatttaca 18000 agtcttgaaa ttccacgtag gaatgtggca actttacaag ctgaaaatgt aacaggactc 18060 tttaaagatt gtagtaaggt aatcactggg ttacatccta cacaggcacc tacacacctc 18120 agtgttgaca ctaaattcaa aactgaaggt ttatgtgttg acatacctgg catacctaag 18180 gacatgacct atagaagact catctctatg atgggtttta aaatgaatta tcaagttaat 18240 ggttacccta acatgtttat cacccgcgaa gaagctataa gacatgtacg tgcatggatt 18300 ggcttcgatg tcgaggggtg tcatgctact agagaagctg ttggtaccaa tttaccttta 18360 cagctaggtt tttctacagg tgttaaccta gttgctgtac ctacaggtta tgttgataca 18420 cctaataata cagatttttc cagagttagt gctaaaccac cgcctggaga tcaatttaaa 18480 cacctcatac cacttatgta caaaggactt ccttggaatg tagtgcgtat aaagattgta 18540 caaatgttaa gtgacacact taaaaatctc tctgacagag tcgtatttgt cttatgggca 18600 catggctttg agttgacatc tatgaagtat tttgtgaaaa taggacctga gcgcacctgt 18660 tgtctatgtg atagacgtgc cacatgcttt tccactgctt cagacactta tgcctgttgg 18720 catcattcta ttggatttga ttacgtctat aatccgttta tgattgatgt tcaacaatgg 18780 ggttttacag gtaacctaca aagcaaccat gatctgtatt gtcaagtcca tggtaatgca 18840 catgtagcta gttgtgatgc aatcatgact aggtgtctag ctgtccacga gtgctttgtt 18900 aagcgtgttg actggactat tgaatatcct ataattggtg atgaactgaa gattaatgcg 18960 gcttgtagaa aggttcaaca catggttgtt aaagctgcat tattagcaga caaattccca 19020 gttcttcacg acattggtaa ccctaaagct attaagtgtg tacctcaagc tgatgtagaa 19080 tggaagttct atgatgcaca gccttgtagt gacaaagctt ataaaataga agaattattc 19140 tattcttatg ccacacattc tgacaaattc acagatggtg tatgcctatt ttggaattgc 19200 aatgtcgata gatatcctgc taattccatt gtttgtagat ttgacactag agtgctatct 19260 aaccttaact tgcctggttg tgatggtggc agtttgtatg taaataaaca tgcattccac 19320 acaccagctt ttgataaaag tgcttttgtt aatttaaaac aattaccatt tttctattac 19380 tctgacagtc catgtgagtc tcatggaaaa caagtagtgt cagatataga ttatgtacca 19440 ctaaagtctg ctacgtgtat aacacgttgc aatttaggtg gtgctgtctg tagacatcat 19500 gctaatgagt acagattgta tctcgatgct tataacatga tgatctcagc tggctttagc 19560 ttgtgggttt acaaacaatt tgatacttat aacctctgga acacttttac aagacttcag 19620 agtttagaaa atgtggcttt taatgttgta aataagggac actttgatgg acaacagggt 19680 gaagtaccag tttctatcat taataacact gtttacacaa aagttgatgg tgttgatgta 19740 gaattgtttg aaaataaaac aacattacct gttaatgtag catttgagct ttgggctaag 19800 cgcaacatta aaccagtacc agaggtgaaa atactcaata atttgggtgt ggacattgct 19860 gctaatactg tgatctggga ctacaaaaga gatgctccag cacatatatc tactattggt 19920 gtttgttcta tgactgacat agccaagaaa ccaactgaaa cgatttgtgc accactcact 19980 gtcttttttg atggtagagt tgatggtcaa gtagacttat ttagaaatgc ccgtaatggt 20040 gttcttatta cagaaggtag tgttaaaggt ttacaaccat ctgtaggtcc caaacaagct 20100 agtcttaatg gagtcacatt aattggagaa gccgtaaaaa cacagttcaa ttattataag 20160 aaagttgatg gtgttgtcca acaattacct gaaacttact ttactcagag tagaaattta 20220 caagaattta aacccaggag tcaaatggaa attgatttct tagaattagc tatggatgaa 20280 ttcattgaac ggtataaatt agaaggctat gccttcgaac atatcgttta tggagatttt 20340 agtcatagtc agttaggtgg tttacatcta ctgattggac tagctaaacg ttttaaggaa 20400 tcaccttttg aattagaaga ttttattcct atggacagta cagttaaaaa ctatttcata 20460 acagatgcgc aaacaggttc atctaagtgt gtgtgttctg ttattgattt attacttgat 20520 gattttgttg aaataataaa atcccaagat ttatctgtag tttctaaggt tgtcaaagtg 20580 actattgact atacagaaat ttcatttatg ctttggtgta aagatggcca tgtagaaaca 20640 ttttacccaa aattacaatc tagtcaagcg tggcaaccgg gtgttgctat gcctaatctt 20700 tacaaaatgc aaagaatgct attagaaaag tgtgaccttc aaaattatgg tgatagtgca 20760 acattaccta aaggcataat gatgaatgtc gcaaaatata ctcaactgtg tcaatattta 20820 aacacattaa cattagctgt accctataat atgagagtta tacattttgg tgctggttct 20880 gataaaggag ttgcaccagg tacagctgtt ttaagacagt ggttgcctac gggtacgctg 20940 cttgtcgatt cagatcttaa tgactttgtc tctgatgcag attcaacttt gattggtgat 21000 tgtgcaactg tacatacagc taataaatgg gatctcatta ttagtgatat gtacgaccct 21060 aagactaaaa atgttacaaa agaaaatgac tctaaagagg gttttttcac ttacatttgt 21120 gggtttatac aacaaaagct agctcttgga ggttccgtgg ctataaagat aacagaacat 21180 tcttggaatg ctgatcttta taagctcatg ggacacttcg catggtggac agcctttgtt 21240 actaatgtga atgcgtcatc atctgaagca tttttaattg gatgtaatta tcttggcaaa 21300 ccacgcgaac aaatagatgg ttatgtcatg catgcaaatt acatattttg gaggaataca 21360 aatccaattc agttgtcttc ctattcttta tttgacatga gtaaatttcc ccttaaatta 21420 aggggtactg ctgttatgtc tttaaaagaa ggtcaaatca atgatatgat tttatctctt 21480 cttagtaaag gtagacttat aattagagaa aacaacagag ttgttatttc tagtgatgtt 21540 cttgttaaca actaaacgaa caatgtttgt ttttcttgtt ttattgccac tagtctctag 21600 tcagtgtgtt aatcttacaa ccagaactca attaccccct gcatacacta attctttcac 21660 acgtggtgtt tattaccctg acaaagtttt cagatcctca gttttacatt caactcagga 21720 cttgttctta cctttctttt ccaatgttac ttggttccat gctatacatg tctctgggac 21780 caatggtact aagaggtttg ataaccctgt cctaccattt aatgatggtg tttattttgc 21840 ttccactgag aagtctaaca taataagagg ctggattttt ggtactactt tagattcgaa 21900 gacccagtcc ctacttattg ttaataacgc tactaatgtt gttattaaag tctgtgaatt 21960 tcaattttgt aatgatccat ttttgggtgt ttattaccac aaaaacaaca aaagttggat 22020 ggaaagtgag ttcagagttt attctagtgc gaataattgc acttttgaat atgtctctca 22080 gccttttctt atggaccttg aaggaaaaca gggtaatttc aaaaatctta gggaatttgt 22140 gtttaagaat attgatggtt attttaaaat atattctaag cacacgccta ttaatttagt 22200 gcgtgatctc cctcagggtt tttcggcttt agaaccattg gtagatttgc caataggtat 22260 taacatcact aggtttcaaa ctttacttgc tttacataga agttatttga ctcctggtga 22320 ttcttcttca ggttggacag ctggtgctgc agcttattat gtgggttatc ttcaacctag 22380 gacttttcta ttaaaatata atgaaaatgg aaccattaca gatgctgtag actgtgcact 22440 tgaccctctc tcagaaacaa agtgtacgtt gaaatccttc actgtagaaa aaggaatcta 22500 tcaaacttct aactttagag kccaaccaac agaatctatt gttagatttc ctaatattac 22560 aaacttgtgc ccttttggtg aagtttttaa cgccaccaga tttgcatctg tttatgcttg 22620 gaacaggaag agaatcagca actgtgttgc tgattattct gtcctatata attccgcatc 22680 attttccact tttaagtgtt atggagtgtc tcctactaaa ttaaatgatc tctgctttac 22740 taatgtctat gcagattcat ttgtaattag aggtgatgaa gtcagacaaa tcgctccagg 22800 gcaaactgga aagattgctg attataatta taaattacca gatgatttta caggctgcgt 22860 tatagcttgg aattctaaca atcttgattc taaggttggt ggtaattata attacctgta 22920 tagattgttt aggaagtcta atctcaaacc ttttgagaga gatatttcaa ctgaaatcta 22980 tcaggccggt agcacacctt gtaatggtgt tgaaggtttt aattgttact ttcctttaca 23040 atcatatggt ttccaaccca ctaatggtgt tggttaccaa ccatacagag tagtagtact 23100 ttcttttgaa cttctacatg caccagcaac tgtttgtgga cctaaaaagt ctactaattt 23160 ggttaaaaac aaatgtgtca atttcaactt caatggttta acaggcacag gtgttcttac 23220 tgagtctaac aaaaagtttc tgcctttcca acaatttggc agagacattg ctgacactac 23280 tgatgctgtc cgtgatccac agacacttga gattcttgac attacaccat gttcttttgg 23340 tggtgtcagt gttataacac caggaacaaa tacttctaac caggttgctg ttctttatca 23400 gggtgttaac tgcacagaag tccctgttgc tattcatgca gatcaactta ctcctacttg 23460 gcgtgtttat tctacaggtt ctaatgtttt tcaaacacgt gcaggctgtt taataggggc 23520 tgaacatgtc aacaactcat atgagtgtga catacccatt ggtgcaggta tatgcgctag 23580 ttatcagact cagactaatt ctcctcggcg ggcacgtagt gtagctagtc aatccatcat 23640 tgcctacact atgtcacttg gtgcagaaaa ttcagttgct tactctrata actctattgc 23700 catacccaca aattttacta ttagtgttac cacagaaatt ctaccagtgt ctatgaccaa 23760 gacatcagta gattgtacaa tgtacatttg tggtgattca actgaatgca gcaatctttt 23820 gttgcaatat ggcagttttt gtacacaatt aaaccgtgct ttaactggaa tagctgttga 23880 acaagacaaa aacacccaag aagtttttgc acaagtcaaa caaatttaca aaacaccacc 23940 aattaaagat tttggtggtt ttaatttttc acaaatatta ccagatccat caaaaccaag 24000 caagaggtca tttattgaag atctactttt caacaaagtg acacttgcag atgctggctt 24060 catcaaacaa tatggtgatt gccttggtga tattgctgct agagacctca tttgtgcaca 24120 aaagtttaac ggccttactg ttttgccacc tttgctcaca gatgaaatga ttgctcaata 24180 cacttctgca ctgttagcgg gtacaatcac ttctggttgg acctttggtg caggtgctgc 24240 attacaaata ccatttgcta tgcaaatggc ttataggttt aatggtattg gagttacaca 24300 gaatgttctc tatgagaacc aaaaattgat tgccaaccaa tttaatagtg ctattggcaa 24360 aattcaagac tcactttctt ccacagcaag tgcacttgga aaacttcaag atgtggtcaa 24420 ccaaaatgca caagctttaa acacgcttgt taaacaactt agctccaatt ttggtgcaat 24480 ttcaagtgtt ttaaatgata tcctttcacg tcttgacaaa gttgaggctg aagtgcaaat 24540 tgataggttg atcacaggca gacttcaaag tttgcagaca tatgtgactc aacaattaat 24600 tagagctgca gaaatcagag tttctgctaa tcttgctgct actaaaatgt cagagtgtgt 24660 acttggacaa tcaaaaagag ttgatttttg tggaaagggc tatcatctta tgtccttccc 24720 tcagtcagca cctcatggtg tagtcttctt gcatgtgact tatgtccctg cacaagaaaa 24780 gaacttcaca actgctcctg ccatttgtca tgatggaaaa gcacactttc ctcgtgaagg 24840 tgtctttgtt tcaaatggca cacactggtt tgtaacacaa aggaattttt atgaaccaca 24900 aatcattact acagacaaca catttgtgtc tggtaactgt gatgttgtaa taggaattgt 24960 caacaacaca gtttatgatc ctttgcaacc tgaattagac tcattcaagg aggagttaga 25020 taaatatttt aagaatcata catcaccaga tgttgattta ggtgacatct ctggcattaa 25080 tgcttcagtt gtaaacattc aaaaagaaat tgaccgcctc aatgaggttg ccaagaattt 25140 aaatgaatct ctcatcgatc tccaagaact tggaaagtat gagcagtata taaaatggcc 25200 atggtacatt tggctaggtt ttatagctgg cttgattgcc atagtaatgg tgacaattat 25260 gctttgctgt atgaccagtt gctgtagttg tctcaagggc tgttgttctt gtggatcctg 25320 ctgcaaattt gatgaagacg actctgagcc agtgctcaaa ggagtcaaat tacattacac 25380 ataaacgaac ttatggattt gtttatgaga atcttcacaa ttggaactgt aactttgaag 25440 caaggtgaaa tcaaggatgc tactccttca gattttgttc gcgctactgc aacgataccg 25500 atacaagcct cactcccttt cggatggctt attgttggcg ttgcacttct tgctgttttt 25560 cagagcgctt ccaaaatcat aaccctcaaa aagagatggc aactagcact ctccaagggt 25620 gttcactttg tttgcaactt gctgttgttg tttgtaacag tttactcaca ccttttgctc 25680 gttgctgctg gccttgaagc cccttttctc tatctttatg ctttagtcta cttcttgcag 25740 agtataaact ttgtaagaat aataatgagg ctttggcttt gctggaaatg ccgttccaaa 25800 aacccattac tttatgatgc caactatttt ctttgctggc atactaattg ttacgactat 25860 tgtatacctt acaatagtgt aacttcttca attgtcatta cttcaggtga tggcacaaca 25920 agtcctattt ctgaacatga ctaccagatt ggtggttata ctgaaaaatg ggaatctgga 25980 gtaaaagact gtgttgtatt acacagttac ttcacttcag actattacca gctgtactca 26040 actcaattga gtacagacac tggtgttgaa catgttacct tcttcatcta caataaaatt 26100 gttgatgagc ctgaagaaca tgtccaaatt cacacaatcg acggttcatc cggagttgtt 26160 aatccagtaa tggaaccaat ttatgatgaa ccgacgacga ctactagcgt gcctttgtaa 26220 gcacaagctg atgagtacga acttatgtac tcattcgttt cggaagagmc aggtacgtta 26280 atagttaata gcgtacttct ttttcttgct ttcgtggtat tcttgctagt tacactagcc 26340 atccttactg cgcttcgatt gtgtgcgtac tgctgcaata ttgttaacgt gagtcttgta 26400 aaaccttctt tttacgttta ctctcgtgtt aaaaatctga attcttctag agttcctgat 26460 cttctggtct aaacgaacta aatattatat tagtttttct gtttggaact ttaattttag 26520 ccatggcaga ttccaacggt actattaccg ttgaagagct taaaaagctc cttgaacaat 26580 ggaacctagt aataggtttc ctattcctta catggatttg tcttctacaa tttgcctatg 26640 ccaacaggaa taggtttttg tatataatta agttaatttt cctctggctg ttatggccag 26700 taactttagc ttgttttgtg cttgctgctg tttacagaat aaattggatc accggtggaa 26760 ttgctatcgc aatggcttgt cttgtaggct tgatgtggct cagctacttc attgcttctt 26820 tcagactgtt tgcgcgtacg cgttccatgt ggtcattcaa tccagaaact aacattcttc 26880 tcaacgtgcc actccatggc actattctga ccagaccgct tctagaaagt gaactcgtaa 26940 tcggagctgt gatccttcgt ggacatcttc gtattgctgg acaccatcta ggacgctgtg 27000 acatcaagga cctgcctaaa gaaatcactg ttgctacatc acgaatgctt tcttattaca 27060 aattgggagc ttcgcagcgt gtagcaggtg actcaggttt tgctgcatac agtcgctaca 27120 ggattggcaa ctataaatta aacacagacc attccagtag cagtgacaat attgctttgc 27180 ttgtacagta agtgacaaca gatgtttcat ctcgttgact ttcaggttac tatagcagag 27240 atattactaa ttattatgag gacttttaaa gtttccattt ggaatcttga ttacatcata 27300 aacctcataa ttaaaaattt atctaagtca ctaactgaga ataaatattc tcaattagat 27360 gaagagcaac caatggagat tgattaaacg aacatgaaaa ttattctttt cttggcactg 27420 ataacactcg ctacttgtga gctttatcac taccaagagt gtgttagagg tacaacagta 27480 cttttaaaag aaccttgctc ttctggaaca tacgagggca attcaccatt tcatcctcta 27540 gctgataaca aatttgcact gacttgcttt agcactcaat ttgcttttgc ttgtcctgac 27600 ggcgtaaaac acgtctatca gttacgtgcc agatcagttt cacctaaact gttcatcaga 27660 caagaggaag ttcaagaact ttactctcca atttttctta ttgttgcggc aatagtgttt 27720 ataacacttt gcttcacact caaaagaaag acagaatgat tgaactttca ttaattgact 27780 tctatttgtg ctttttagcc tttctgctat tccttgtttt aattatgctt attatctttt 27840 ggttctcact tgaactgcaa gatcataatg aaacttgtca cgcctaaacg aacatgaaat 27900 ttcttgtttt cttaggaatc atcacaactg tagctgcatt tcaccaagaa tgtagtttac 27960 agtcatgtac tcaacatcaa ccatatgtag ttgatgaccc gtgtcctatt cacttctatt 28020 ctaaatggta tattagagta ggagctagaa aatcagcacc tttaattgaa ttgtgcgtgg 28080 atgaggctgg ttctaaatca cccattcagt acatcgatat cggtaattat acagtttcct 28140 gtttaccttt tacaattaat tgccaggaac ctaaattggg tagtcttgta gtgcgttgtt 28200 cgttctatga agacttttta gagtatcatg acgttcgtgt tgttttagat ttcatctaaa 28260 cgaacaaact aaaatgtctg ataatggacc ccaaaatcag cgaaatgcac cccgcattac 28320 gtttggtgga ccctcagatt caactggcag taaccagaat ggagaacgca gtggggcgcg 28380 atcaaaacaa cgtcggcccc aaggtttacc caataatact gcgtcttggt tcaccgctct 28440 cactcaacat ggcaaggaag accttaaatt ccctcgagga caaggcgttc caattaacac 28500 caatagcagt ccagatgacc aaattggcta ctaccgaaga gctaccagac gaattcgtgg 28560 tggtgacggt aaaatgaaag atctcagtcc aagatggtat ttctactacc taggaactgg 28620 gccagaagct ggacttccct atggtgctaa caaagacggc atcatatggg ttgcaactga 28680 gggagccttg aatacaccaa aagatcacat tggcacccgc aatcctgcta acaatgctgc 28740 aatcgtgcta caacttcctc aaggaacaac attgccaaaa ggcttctacg cagaagggag 28800 cagaggcggc agtcaagcct cttctcgttc ctcatcacgt agtcgcaaca gttcaagaaa 28860 ttcaactcca ggcagcagta aacgaacttc tcctgctaga atggctggca atggcggtga 28920 tgctgctctt gctttgctgc tgcttgacag attgaaccag cttgagagca aaatgtctgg 28980 taaaggccaa caacaacaag gccaaactgt cactaagaaa tctgctgctg aggcttctaa 29040 gaagcctcgg caaaaacgta ctgccactaa agcatacaat gtaacacaag ctttcggcag 29100 acgtggtcca gaacaaaccc aaggaaattt tggggaccag gaactaatca gacaaggaac 29160 tgattacaaa cattggccgc aaattgcaca atttgccccc agcgcttcag cgttcttcgg 29220 aatgtcgcgc attggcatgg aagtcacacc ttcgggaacg tggttgacct acacaggtgc 29280 catcaaattg gatgacaaag atccaaattt caaagatcaa gtcattttgc tgaataagca 29340 tattgacgca tacaaaacat tcccaccaac agagcctaaa aaggacaaaa agaagaaggc 29400 tgatgaaact caagccttac cgcagagaca gaagaaacag caaactgtga ctcttcttcc 29460 tgctgcagat ttggatgatt tctccaaaca attgcaacaa tccatgagca gtgctgactc 29520 aactcaggcc taaactcatg cagaccacac aaggcagatg ggctatataa acgttttcgc 29580 ttttccgttt acgatatata gtctactctt gtgcagaatg aattctcgta actacatagc 29640 acaagtagat gtagttaact ttaatctcac atagcaatct ttaatcagtg tgtaacatta 29700 gggaggactt gaaagagcca ccacattttc accgaggcca cgcggagtac gatcgagtgt 29760 acagtgaaca atgctaggga gagctgccta tatggaagag ccctaatgtg taaaattaat 29820 tttagtagtg ctatccccat gtgattttaa tagcttctta ggagnatgac annnnnnnnn 29880 nnnnn 29885 <210> 16 <211> 4405 <212> PRT <213> SARS-CoV2 <400> 16 Met Glu Ser Leu Val Pro Gly Phe Asn Glu Lys Thr Hes Val Gln Leu 1 5 10 15 Ser Leu Pro Val Leu Gln Val Arg Asp Val Leu Val Arg Gly Phe Gly 20 25 30 Asp Ser Val Glu Glu Val Leu Ser Glu Ala Arg Gln Hes Leu Lys Asp 35 40 45 Gly Thr Cys Gly Leu Val Glu Val Glu Lys Gly Val Leu Pro Gln Leu 50 55 60 Glu Gln Pro Tyr Val Phe Ile Lys Arg Ser Asp Ala Arg Thr Ala Pro 65 70 75 80 Hes Gly Hes Val Met Val Glu Leu Val Ala Glu Leu Glu Gly Ile Gln 85 90 95 Tyr Gly Arg Ser Gly Glu Thr Leu Gly Val Leu Val Pro Hes Val Gly 100 105 110 Glu Ile Pro Val Ala Tyr Arg Lys Val Leu Leu Arg Lys Asn Gly Asn 115 120 125 Lys Gly Ala Gly Gly Hes Ser Tyr Gly Ala Asp Leu Lys Ser Phe Asp 130 135 140 Leu Gly Asp Glu Leu Gly Thr Asp Pro Tyr Glu Asp Phe Gln Glu Asn 145 150 155 160 Trp Asn Thr Lys Hes Ser Ser Gly Val Thr Arg Glu Leu Met Arg Glu 165 170 175 Leu Asn Gly Gly Ala Tyr Thr Arg Tyr Val Asp Asn Asn Phe Cys Gly 180 185 190 Pro Asp Gly Tyr Pro Leu Glu Cys Ile Lys Asp Leu Leu Ala Arg Ala 195 200 205 Gly Lys Ala Ser Cys Thr Leu Ser Glu Gln Leu Asp Phe Ile Asp Thr 210 215 220 Lys Arg Gly Val Tyr Cys Cys Arg Glu Hes Glu Hes Glu Ile Ala Trp 225 230 235 240 Tyr Thr Glu Arg Ser Glu Lys Ser Tyr Glu Leu Gln Thr Pro Phe Glu 245 250 255 Ile Lys Leu Ala Lys Lys Phe Asp Thr Phe Asn Gly Glu Cys Pro Asn 260 265 270 Phe Val Phe Pro Leu Asn Ser Ile Ile Lys Thr Ile Gln Pro Arg Val 275 280 285 Glu Lys Lys Lys Leu Asp Gly Phe Met Gly Arg Ile Arg Ser Val Tyr 290 295 300 Pro Val Ala Ser Pro Asn Glu Cys Asn Gln Met Cys Leu Ser Thr Leu 305 310 315 320 Met Lys Cys Asp Hes Cys Gly Glu Thr Ser Trp Gln Thr Gly Asp Phe 325 330 335 Val Lys Ala Thr Cys Glu Phe Cys Gly Thr Glu Asn Leu Thr Lys Glu 340 345 350 Gly Ala Thr Thr Cys Gly Tyr Leu Pro Gln Asn Ala Val Val Lys Ile 355 360 365 Tyr Cys Pro Ala Cys Hes Asn Ser Glu Val Gly Pro Glu Hes Ser Leu 370 375 380 Ala Glu Tyr Hes Asn Glu Ser Gly Leu Lys Thr Ile Leu Arg Lys Gly 385 390 395 400 Gly Arg Thr Ile Ala Phe Gly Gly Cys Val Phe Ser Tyr Val Gly Cys 405 410 415 Hes Asn Lys Cys Ala Tyr Trp Val Pro Arg Ala Ser Ala Asn Ile Gly 420 425 430 Cys Asn Hes Thr Gly Val Val Gly Glu Gly Ser Glu Gly Leu Asn Asp 435 440 445 Asn Leu Leu Glu Ile Leu Gln Lys Glu Lys Val Asn Ile Asn Ile Val 450 455 460 Gly Asp Phe Lys Leu Asn Glu Glu Ile Ala Ile Ile Leu Ala Ser Phe 465 470 475 480 Ser Ala Ser Thr Ser Ala Phe Val Glu Thr Val Lys Gly Leu Asp Tyr 485 490 495 Lys Ala Phe Lys Gln Ile Val Glu Ser Cys Gly Asn Phe Lys Val Thr 500 505 510 Lys Gly Lys Ala Lys Lys Gly Ala Trp Asn Ile Gly Glu Gln Lys Ser 515 520 525 Ile Leu Ser Pro Leu Tyr Ala Phe Ala Ser Glu Ala Ala Arg Val Val 530 535 540 Arg Ser Ile Phe Ser Arg Thr Leu Glu Thr Ala Gln Asn Ser Val Arg 545 550 555 560 Val Leu Gln Lys Ala Ala Ile Thr Ile Leu Asp Gly Ile Ser Gln Tyr 565 570 575 Ser Leu Arg Leu Ile Asp Ala Met Met Phe Thr Ser Asp Leu Ala Thr 580 585 590 Asn Asn Leu Val Val Met Ala Tyr Ile Thr Gly Gly Val Val Gln Leu 595 600 605 Thr Ser Gln Trp Leu Thr Asn Ile Phe Gly Thr Val Tyr Glu Lys Leu 610 615 620 Lys Pro Val Leu Asp Trp Leu Glu Glu Lys Phe Lys Glu Gly Val Glu 625 630 635 640 Phe Leu Arg Asp Gly Trp Glu Ile Val Lys Phe Ile Ser Thr Cys Ala 645 650 655 Cys Glu Ile Val Gly Gly Gln Ile Val Thr Cys Ala Lys Glu Ile Lys 660 665 670 Glu Ser Val Gln Thr Phe Phe Lys Leu Val Asn Lys Phe Leu Ala Leu 675 680 685 Cys Ala Asp Ser Ile Ile Ile Gly Gly Ala Lys Leu Lys Ala Leu Asn 690 695 700 Leu Gly Glu Thr Phe Val Thr Hes Ser Lys Gly Leu Tyr Arg Lys Cys 705 710 715 720 Val Lys Ser Arg Glu Glu Thr Gly Leu Leu Met Pro Leu Lys Ala Pro 725 730 735 Lys Glu Ile Ile Phe Leu Glu Gly Glu Thr Leu Pro Thr Glu Val Leu 740 745 750 Thr Glu Glu Val Val Leu Lys Thr Gly Asp Leu Gln Pro Leu Glu Gln 755 760 765 Pro Thr Ser Glu Ala Val Glu Ala Pro Leu Val Gly Thr Pro Val Cys 770 775 780 Ile Asn Gly Leu Met Leu Leu Glu Ile Lys Asp Thr Glu Lys Tyr Cys 785 790 795 800 Ala Leu Ala Pro Asn Met Met Val Thr Asn Asn Thr Phe Thr Leu Lys 805 810 815 Gly Gly Ala Pro Thr Lys Val Thr Phe Gly Asp Asp Thr Val Ile Glu 820 825 830 Val Gln Gly Tyr Lys Ser Val Asn Ile Thr Phe Glu Leu Asp Glu Arg 835 840 845 Ile Asp Lys Val Leu Asn Glu Lys Cys Ser Ala Tyr Thr Val Glu Leu 850 855 860 Gly Thr Glu Val Asn Glu Phe Ala Cys Val Val Ala Asp Ala Val Ile 865 870 875 880 Lys Thr Leu Gln Pro Val Ser Glu Leu Leu Thr Pro Leu Gly Ile Asp 885 890 895 Leu Asp Glu Trp Ser Met Ala Thr Tyr Tyr Leu Phe Asp Glu Ser Gly 900 905 910 Glu Phe Lys Leu Ala Ser Hes Met Tyr Cys Ser Phe Tyr Pro Pro Asp 915 920 925 Glu Asp Glu Glu Glu Gly Asp Cys Glu Glu Glu Glu Phe Glu Pro Ser 930 935 940 Thr Gln Tyr Glu Tyr Gly Thr Glu Asp Asp Tyr Gln Gly Lys Pro Leu 945 950 955 960 Glu Phe Gly Ala Thr Ser Ala Ala Leu Gln Pro Glu Glu Glu Gln Glu 965 970 975 Glu Asp Trp Leu Asp Asp Asp Ser Gln Gln Thr Val Gly Gln Gln Asp 980 985 990 Gly Ser Glu Asp Asn Gln Thr Thr Thr Ile Gln Thr Ile Val Glu Val 995 1000 1005 Gln Pro Gln Leu Glu Met Glu Leu Thr Pro Val Val Gln Thr Ile 1010 1015 1020 Glu Val Asn Ser Phe Ser Gly Tyr Leu Lys Leu Thr Asp Asn Val 1025 1030 1035 Tyr Ile Lys Asn Ala Asp Ile Val Glu Glu Ala Lys Lys Val Lys 1040 1045 1050 Pro Thr Val Val Val Asn Ala Ala Asn Val Tyr Leu Lys Hes Gly 1055 1060 1065 Gly Gly Val Ala Gly Ala Leu Asn Lys Ala Thr Asn Asn Ala Met 1070 1075 1080 Gln Val Glu Ser Asp Asp Tyr Ile Ala Thr Asn Gly Pro Leu Lys 1085 1090 1095 Val Gly Gly Ser Cys Val Leu Ser Gly Hes Asn Leu Ala Lys Hes 1100 1105 1110 Cys Leu Hes Val Val Gly Pro Asn Val Asn Lys Gly Glu Asp Ile 1115 1120 1125 Gln Leu Leu Lys Ser Ala Tyr Glu Asn Phe Asn Gln Hes Glu Val 1130 1135 1140 Leu Leu Ala Pro Leu Leu Ser Ala Gly Ile Phe Gly Ala Asp Pro 1145 1150 1155 Ile Hes Ser Leu Arg Val Cys Val Asp Thr Val Arg Thr Asn Val 1160 1165 1170 Tyr Leu Ala Val Phe Asp Lys Asn Leu Tyr Asp Lys Leu Val Ser 1175 1180 1185 Ser Phe Leu Glu Met Lys Ser Glu Lys Gln Val Glu Gln Lys Ile 1190 1195 1200 Ala Glu Ile Pro Lys Glu Glu Val Lys Pro Phe Ile Thr Glu Ser 1205 1210 1215 Lys Pro Ser Val Glu Gln Arg Lys Gln Asp Asp Lys Lys Ile Lys 1220 1225 1230 Ala Cys Val Glu Glu Val Thr Thr Thr Leu Glu Glu Thr Lys Phe 1235 1240 1245 Leu Thr Glu Asn Leu Leu Leu Tyr Ile Asp Ile Asn Gly Asn Leu 1250 1255 1260 Hes Pro Asp Ser Ala Thr Leu Val Ser Asp Ile Asp Ile Thr Phe 1265 1270 1275 Leu Lys Lys Asp Ala Pro Tyr Ile Val Gly Asp Val Val Gln Glu 1280 1285 1290 Gly Val Leu Thr Ala Val Val Ile Pro Thr Lys Lys Ala Gly Gly 1295 1300 1305 Thr Thr Glu Met Leu Ala Lys Ala Leu Arg Lys Val Pro Thr Asp 1310 1315 1320 Asn Tyr Ile Thr Thr Tyr Pro Gly Gln Gly Leu Asn Gly Tyr Thr 1325 1330 1335 Val Glu Glu Ala Lys Thr Val Leu Lys Lys Cys Lys Ser Ala Phe 1340 1345 1350 Tyr Ile Leu Pro Ser Ile Ile Ser Asn Glu Lys Gln Glu Ile Leu 1355 1360 1365 Gly Thr Val Ser Trp Asn Leu Arg Glu Met Leu Ala Hes Ala Glu 1370 1375 1380 Glu Thr Arg Lys Leu Met Pro Val Cys Val Glu Thr Lys Ala Ile 1385 1390 1395 Val Ser Thr Ile Gln Arg Lys Tyr Lys Gly Ile Lys Ile Gln Glu 1400 1405 1410 Gly Val Val Asp Tyr Gly Ala Arg Phe Tyr Phe Tyr Thr Ser Lys 1415 1420 1425 Thr Thr Val Ala Ser Leu Ile Asn Thr Leu Asn Asp Leu Asn Glu 1430 1435 1440 Thr Leu Val Thr Met Pro Leu Gly Tyr Val Thr Hes Gly Leu Asn 1445 1450 1455 Leu Glu Glu Ala Ala Arg Tyr Met Arg Ser Leu Lys Val Pro Ala 1460 1465 1470 Thr Val Ser Val Ser Ser Pro Asp Ala Val Thr Ala Tyr Asn Gly 1475 1480 1485 Tyr Leu Thr Ser Ser Ser Lys Thr Pro Glu Glu Hes Phe Ile Glu 1490 1495 1500 Thr Ile Ser Leu Ala Gly Ser Tyr Lys Asp Trp Ser Tyr Ser Gly 1505 1510 1515 Gln Ser Thr Gln Leu Gly Ile Glu Phe Leu Lys Arg Gly Asp Lys 1520 1525 1530 Ser Val Tyr Tyr Thr Ser Asn Pro Thr Thr Phe Hes Leu Asp Gly 1535 1540 1545 Glu Val Ile Thr Phe Asp Asn Leu Lys Thr Leu Leu Ser Leu Arg 1550 1555 1560 Glu Val Arg Thr Ile Lys Val Phe Thr Thr Val Asp Asn Ile Asn 1565 1570 1575 Leu Hes Thr Gln Val Val Asp Met Ser Met Thr Tyr Gly Gln Gln 1580 1585 1590 Phe Gly Pro Thr Tyr Leu Asp Gly Ala Asp Val Thr Lys Ile Lys 1595 1600 1605 Pro Hes Asn Ser Hes Glu Gly Lys Thr Phe Tyr Val Leu Pro Asn 1610 1615 1620 Asp Asp Thr Leu Arg Val Glu Ala Phe Glu Tyr Tyr Hes Thr Thr 1625 1630 1635 Asp Pro Ser Phe Leu Gly Arg Tyr Met Ser Ala Leu Asn Hes Thr 1640 1645 1650 Lys Lys Trp Lys Tyr Pro Gln Val Asn Gly Leu Thr Ser Ile Lys 1655 1660 1665 Trp Ala Asp Asn Asn Cys Tyr Leu Ala Thr Ala Leu Leu Thr Leu 1670 1675 1680 Gln Gln Ile Glu Leu Lys Phe Asn Pro Pro Ala Leu Gln Asp Ala 1685 1690 1695 Tyr Tyr Arg Ala Arg Ala Gly Glu Ala Ala Asn Phe Cys Ala Leu 1700 1705 1710 Ile Leu Ala Tyr Cys Asn Lys Thr Val Gly Glu Leu Gly Asp Val 1715 1720 1725 Arg Glu Thr Met Ser Tyr Leu Phe Gln Hes Ala Asn Leu Asp Ser 1730 1735 1740 Cys Lys Arg Val Leu Asn Val Val Cys Lys Thr Cys Gly Gln Gln 1745 1750 1755 Gln Thr Thr Leu Lys Gly Val Glu Ala Val Met Tyr Met Gly Thr 1760 1765 1770 Leu Ser Tyr Glu Gln Phe Lys Lys Gly Val Gln Ile Pro Cys Thr 1775 1780 1785 Cys Gly Lys Gln Ala Thr Lys Tyr Leu Val Gln Gln Glu Ser Pro 1790 1795 1800 Phe Val Met Met Ser Ala Pro Pro Ala Gln Tyr Glu Leu Lys Hes 1805 1810 1815 Gly Thr Phe Thr Cys Ala Ser Glu Tyr Thr Gly Asn Tyr Gln Cys 1820 1825 1830 Gly Hes Tyr Lys Hes Ile Thr Ser Lys Glu Thr Leu Tyr Cys Ile 1835 1840 1845 Asp Gly Ala Leu Leu Thr Lys Ser Ser Glu Tyr Lys Gly Pro Ile 1850 1855 1860 Thr Asp Val Phe Tyr Lys Glu Asn Ser Tyr Thr Thr Thr Ile Lys 1865 1870 1875 Pro Val Thr Tyr Lys Leu Asp Gly Val Val Cys Thr Glu Ile Asp 1880 1885 1890 Pro Lys Leu Asp Asn Tyr Tyr Lys Lys Asp Asn Ser Tyr Phe Thr 1895 1900 1905 Glu Gln Pro Ile Asp Leu Val Pro Asn Gln Pro Tyr Pro Asn Ala 1910 1915 1920 Ser Phe Asp Asn Phe Lys Phe Val Cys Asp Asn Ile Lys Phe Ala 1925 1930 1935 Asp Asp Leu Asn Gln Leu Thr Gly Tyr Lys Lys Pro Ala Ser Arg 1940 1945 1950 Glu Leu Lys Val Thr Phe Phe Pro Asp Leu Asn Gly Asp Val Val 1955 1960 1965 Ala Ile Asp Tyr Lys Hes Tyr Thr Pro Ser Phe Lys Lys Gly Ala 1970 1975 1980 Lys Leu Leu Hes Lys Pro Ile Val Trp Hes Val Asn Asn Ala Thr 1985 1990 1995 Asn Lys Ala Thr Tyr Lys Pro Asn Thr Trp Cys Ile Arg Cys Leu 2000 2005 2010 Trp Ser Thr Lys Pro Val Glu Thr Ser Asn Ser Phe Asp Val Leu 2015 2020 2025 Lys Ser Glu Asp Ala Gln Gly Met Asp Asn Leu Ala Cys Glu Asp 2030 2035 2040 Leu Lys Pro Val Ser Glu Glu Val Val Glu Asn Pro Thr Ile Gln 2045 2050 2055 Lys Asp Val Leu Glu Cys Asn Val Lys Thr Thr Glu Val Val Gly 2060 2065 2070 Asp Ile Ile Leu Lys Pro Ala Asn Asn Ser Leu Lys Ile Thr Glu 2075 2080 2085 Glu Val Gly Hes Thr Asp Leu Met Ala Ala Tyr Val Asp Asn Ser 2090 2095 2100 Ser Leu Thr Ile Lys Lys Pro Asn Glu Leu Ser Arg Val Leu Gly 2105 2110 2115 Leu Lys Thr Leu Ala Thr Hes Gly Leu Ala Ala Val Asn Ser Val 2120 2125 2130 Pro Trp Asp Thr Ile Ala Asn Tyr Ala Lys Pro Phe Leu Asn Lys 2135 2140 2145 Val Val Ser Thr Thr Thr Asn Ile Val Thr Arg Cys Leu Asn Arg 2150 2155 2160 Val Cys Thr Asn Tyr Met Pro Tyr Phe Phe Thr Leu Leu Leu Gln 2165 2170 2175 Leu Cys Thr Phe Thr Arg Ser Thr Asn Ser Arg Ile Lys Ala Ser 2180 2185 2190 Met Pro Thr Thr Ile Ala Lys Asn Thr Val Lys Ser Val Gly Lys 2195 2200 2205 Phe Cys Leu Glu Ala Ser Phe Asn Tyr Leu Lys Ser Pro Asn Phe 2210 2215 2220 Ser Lys Leu Ile Asn Ile Ile Ile Trp Phe Leu Leu Leu Ser Val 2225 2230 2235 Cys Leu Gly Ser Leu Ile Tyr Ser Thr Ala Ala Leu Gly Val Leu 2240 2245 2250 Met Ser Asn Leu Gly Met Pro Ser Tyr Cys Thr Gly Tyr Arg Glu 2255 2260 2265 Gly Tyr Leu Asn Ser Thr Asn Val Thr Ile Ala Thr Tyr Cys Thr 2270 2275 2280 Gly Ser Ile Pro Cys Ser Val Cys Leu Ser Gly Leu Asp Ser Leu 2285 2290 2295 Asp Thr Tyr Pro Ser Leu Glu Thr Ile Gln Ile Thr Ile Ser Ser 2300 2305 2310 Phe Lys Trp Asp Leu Thr Ala Phe Gly Leu Val Ala Glu Trp Phe 2315 2320 2325 Leu Ala Tyr Ile Leu Phe Thr Arg Phe Phe Tyr Val Leu Gly Leu 2330 2335 2340 Ala Ala Ile Met Gln Leu Phe Phe Ser Tyr Phe Ala Val Hes Phe 2345 2350 2355 Ile Ser Asn Ser Trp Leu Met Trp Leu Ile Ile Asn Leu Val Gln 2360 2365 2370 Met Ala Pro Ile Ser Ala Met Val Arg Met Tyr Ile Phe Phe Ala 2375 2380 2385 Ser Phe Tyr Tyr Val Trp Lys Ser Tyr Val Hes Val Val Asp Gly 2390 2395 2400 Cys Asn Ser Ser Thr Cys Met Met Cys Tyr Lys Arg Asn Arg Ala 2405 2410 2415 Thr Arg Val Glu Cys Thr Thr Ile Val Asn Gly Val Arg Arg Ser 2420 2425 2430 Phe Tyr Val Tyr Ala Asn Gly Gly Lys Gly Phe Cys Lys Leu Hes 2435 2440 2445 Asn Trp Asn Cys Val Asn Cys Asp Thr Phe Cys Ala Gly Ser Thr 2450 2455 2460 Phe Ile Ser Asp Glu Val Ala Arg Asp Leu Ser Leu Gln Phe Lys 2465 2470 2475 Arg Pro Ile Asn Pro Thr Asp Gln Ser Ser Tyr Ile Val Asp Ser 2480 2485 2490 Val Thr Val Lys Asn Gly Ser Ile Hes Leu Tyr Phe Asp Lys Ala 2495 2500 2505 Gly Gln Lys Thr Tyr Glu Arg Hes Ser Leu Ser Hes Phe Val Asn 2510 2515 2520 Leu Asp Asn Leu Arg Ala Asn Asn Thr Lys Gly Ser Leu Pro Ile 2525 2530 2535 Asn Val Ile Val Phe Asp Gly Lys Ser Lys Cys Glu Glu Ser Ser 2540 2545 2550 Ala Lys Ser Ala Ser Val Tyr Tyr Ser Gln Leu Met Cys Gln Pro 2555 2560 2565 Ile Leu Leu Leu Asp Gln Ala Leu Val Ser Asp Val Gly Asp Ser 2570 2575 2580 Ala Glu Val Ala Val Lys Met Phe Asp Ala Tyr Val Asn Thr Phe 2585 2590 2595 Ser Ser Thr Phe Asn Val Pro Met Glu Lys Leu Lys Thr Leu Val 2600 2605 2610 Ala Thr Ala Glu Ala Glu Leu Ala Lys Asn Val Ser Leu Asp Asn 2615 2620 2625 Val Leu Ser Thr Phe Ile Ser Ala Ala Arg Gln Gly Phe Val Asp 2630 2635 2640 Ser Asp Val Glu Thr Lys Asp Val Val Glu Cys Leu Lys Leu Ser 2645 2650 2655 Hes Gln Ser Asp Ile Glu Val Thr Gly Asp Ser Cys Asn Asn Tyr 2660 2665 2670 Met Leu Thr Tyr Asn Lys Val Glu Asn Met Thr Pro Arg Asp Leu 2675 2680 2685 Gly Ala Cys Ile Asp Cys Ser Ala Arg Hes Ile Asn Ala Gln Val 2690 2695 2700 Ala Lys Ser Hes Asn Ile Ala Leu Ile Trp Asn Val Lys Asp Phe 2705 2710 2715 Met Ser Leu Ser Glu Gln Leu Arg Lys Gln Ile Arg Ser Ala Ala 2720 2725 2730 Lys Lys Asn Asn Leu Pro Phe Lys Leu Thr Cys Ala Thr Thr Arg 2735 2740 2745 Gln Val Val Asn Val Val Thr Thr Lys Ile Ala Leu Lys Gly Gly 2750 2755 2760 Lys Ile Val Asn Asn Trp Leu Lys Gln Leu Ile Lys Val Thr Leu 2765 2770 2775 Val Phe Leu Phe Val Ala Ala Ile Phe Tyr Leu Ile Thr Pro Val 2780 2785 2790 Hes Val Met Ser Lys Hes Thr Asp Phe Ser Ser Glu Ile Ile Gly 2795 2800 2805 Tyr Lys Ala Ile Asp Gly Gly Val Thr Arg Asp Ile Ala Ser Thr 2810 2815 2820 Asp Thr Cys Phe Ala Asn Lys Hes Ala Asp Phe Asp Thr Trp Phe 2825 2830 2835 Ser Gln Arg Gly Gly Ser Tyr Thr Asn Asp Lys Ala Cys Pro Leu 2840 2845 2850 Ile Ala Ala Val Ile Thr Arg Glu Val Gly Phe Val Val Pro Gly 2855 2860 2865 Leu Pro Gly Thr Ile Leu Arg Thr Thr Asn Gly Asp Phe Leu Hes 2870 2875 2880 Phe Leu Pro Arg Val Phe Ser Ala Val Gly Asn Ile Cys Tyr Thr 2885 2890 2895 Pro Ser Lys Leu Ile Glu Tyr Thr Asp Phe Ala Thr Ser Ala Cys 2900 2905 2910 Val Leu Ala Ala Glu Cys Thr Ile Phe Lys Asp Ala Ser Gly Lys 2915 2920 2925 Pro Val Pro Tyr Cys Tyr Asp Thr Asn Val Leu Glu Gly Ser Val 2930 2935 2940 Ala Tyr Glu Ser Leu Arg Pro Asp Thr Arg Tyr Val Leu Met Asp 2945 2950 2955 Gly Ser Ile Ile Gln Phe Pro Asn Thr Tyr Leu Glu Gly Ser Val 2960 2965 2970 Arg Val Val Thr Thr Phe Asp Ser Glu Tyr Cys Arg Hes Gly Thr 2975 2980 2985 Cys Glu Arg Ser Glu Ala Gly Val Cys Val Ser Thr Ser Gly Arg 2990 2995 3000 Trp Val Leu Asn Asn Asp Tyr Tyr Arg Ser Leu Pro Gly Val Phe 3005 3010 3015 Cys Gly Val Asp Ala Val Asn Leu Leu Thr Asn Met Phe Thr Pro 3020 3025 3030 Leu Ile Gln Pro Ile Gly Ala Leu Asp Ile Ser Ala Ser Ile Val 3035 3040 3045 Ala Gly Gly Ile Val Ala Ile Val Val Thr Cys Leu Ala Tyr Tyr 3050 3055 3060 Phe Met Arg Phe Arg Arg Ala Phe Gly Glu Tyr Ser Hes Val Val 3065 3070 3075 Ala Phe Asn Thr Leu Leu Phe Leu Met Ser Phe Thr Val Leu Cys 3080 3085 3090 Leu Thr Pro Val Tyr Ser Phe Leu Pro Gly Val Tyr Ser Val Ile 3095 3100 3105 Tyr Leu Tyr Leu Thr Phe Tyr Leu Thr Asn Asp Val Ser Phe Leu 3110 3115 3120 Ala Hes Ile Gln Trp Met Val Met Phe Thr Pro Leu Val Pro Phe 3125 3130 3135 Trp Ile Thr Ile Ala Tyr Ile Ile Cys Ile Ser Thr Lys Hes Phe 3140 3145 3150 Tyr Trp Phe Phe Ser Asn Tyr Leu Lys Arg Arg Val Val Phe Asn 3155 3160 3165 Gly Val Ser Phe Ser Thr Phe Glu Glu Ala Ala Leu Cys Thr Phe 3170 3175 3180 Leu Leu Asn Lys Glu Met Tyr Leu Lys Leu Arg Ser Asp Val Leu 3185 3190 3195 Leu Pro Leu Thr Gln Tyr Asn Arg Tyr Leu Ala Leu Tyr Asn Lys 3200 3205 3210 Tyr Lys Tyr Phe Ser Gly Ala Met Asp Thr Thr Ser Tyr Arg Glu 3215 3220 3225 Ala Ala Cys Cys Hes Leu Ala Lys Ala Leu Asn Asp Phe Ser Asn 3230 3235 3240 Ser Gly Ser Asp Val Leu Tyr Gln Pro Pro Gln Thr Ser Ile Thr 3245 3250 3255 Ser Ala Val Leu Gln Ser Gly Phe Arg Lys Met Ala Phe Pro Ser 3260 3265 3270 Gly Lys Val Glu Gly Cys Met Val Gln Val Thr Cys Gly Thr Thr 3275 3280 3285 Thr Leu Asn Gly Leu Trp Leu Asp Asp Val Val Tyr Cys Pro Arg 3290 3295 3300 Hes Val Ile Cys Thr Ser Glu Asp Met Leu Asn Pro Asn Tyr Glu 3305 3310 3315 Asp Leu Leu Ile Arg Lys Ser Asn Hes Asn Phe Leu Val Gln Ala 3320 3325 3330 Gly Asn Val Gln Leu Arg Val Ile Gly Hes Ser Met Gln Asn Cys 3335 3340 3345 Val Leu Lys Leu Lys Val Asp Thr Ala Asn Pro Lys Thr Pro Lys 3350 3355 3360 Tyr Lys Phe Val Arg Ile Gln Pro Gly Gln Thr Phe Ser Val Leu 3365 3370 3375 Ala Cys Tyr Asn Gly Ser Pro Ser Gly Val Tyr Gln Cys Ala Met 3380 3385 3390 Arg Pro Asn Phe Thr Ile Lys Gly Ser Phe Leu Asn Gly Ser Cys 3395 3400 3405 Gly Ser Val Gly Phe Asn Ile Asp Tyr Asp Cys Val Ser Phe Cys 3410 3415 3420 Tyr Met Hes Hes Met Glu Leu Pro Thr Gly Val Hes Ala Gly Thr 3425 3430 3435 Asp Leu Glu Gly Asn Phe Tyr Gly Pro Phe Val Asp Arg Gln Thr 3440 3445 3450 Ala Gln Ala Ala Gly Thr Asp Thr Thr Ile Thr Val Asn Val Leu 3455 3460 3465 Ala Trp Leu Tyr Ala Ala Val Ile Asn Gly Asp Arg Trp Phe Leu 3470 3475 3480 Asn Arg Phe Thr Thr Thr Leu Asn Asp Phe Asn Leu Val Ala Met 3485 3490 3495 Lys Tyr Asn Tyr Glu Pro Leu Thr Gln Asp Hes Val Asp Ile Leu 3500 3505 3510 Gly Pro Leu Ser Ala Gln Thr Gly Ile Ala Val Leu Asp Met Cys 3515 3520 3525 Ala Ser Leu Lys Glu Leu Leu Gln Asn Gly Met Asn Gly Arg Thr 3530 3535 3540 Ile Leu Gly Ser Ala Leu Leu Glu Asp Glu Phe Thr Pro Phe Asp 3545 3550 3555 Val Val Arg Gln Cys Ser Gly Val Thr Phe Gln Ser Ala Val Lys 3560 3565 3570 Arg Thr Ile Lys Gly Thr Hes Hes Trp Leu Leu Leu Thr Ile Leu 3575 3580 3585 Thr Ser Leu Leu Val Leu Val Gln Ser Thr Gln Trp Ser Leu Phe 3590 3595 3600 Phe Phe Leu Tyr Glu Asn Ala Phe Leu Pro Phe Ala Met Gly Ile 3605 3610 3615 Ile Ala Met Ser Ala Phe Ala Met Met Phe Val Lys Hes Lys Hes 3620 3625 3630 Ala Phe Leu Cys Leu Phe Leu Leu Pro Ser Leu Ala Thr Val Ala 3635 3640 3645 Tyr Phe Asn Met Val Tyr Met Pro Ala Ser Trp Val Met Arg Ile 3650 3655 3660 Met Thr Trp Leu Asp Met Val Asp Thr Ser Leu Ser Gly Phe Lys 3665 3670 3675 Leu Lys Asp Cys Val Met Tyr Ala Ser Ala Val Val Leu Leu Ile 3680 3685 3690 Leu Met Thr Ala Arg Thr Val Tyr Asp Asp Gly Ala Arg Arg Val 3695 3700 3705 Trp Thr Leu Met Asn Val Leu Thr Leu Val Tyr Lys Val Tyr Tyr 3710 3715 3720 Gly Asn Ala Leu Asp Gln Ala Ile Ser Met Trp Ala Leu Ile Ile 3725 3730 3735 Ser Val Thr Ser Asn Tyr Ser Gly Val Val Thr Thr Val Met Phe 3740 3745 3750 Leu Ala Arg Gly Ile Val Phe Met Cys Val Glu Tyr Cys Pro Ile 3755 3760 3765 Phe Phe Ile Thr Gly Asn Thr Leu Gln Cys Ile Met Leu Val Tyr 3770 3775 3780 Cys Phe Leu Gly Tyr Phe Cys Thr Cys Tyr Phe Gly Leu Phe Cys 3785 3790 3795 Leu Leu Asn Arg Tyr Phe Arg Leu Thr Leu Gly Val Tyr Asp Tyr 3800 3805 3810 Leu Val Ser Thr Gln Glu Phe Arg Tyr Met Asn Ser Gln Gly Leu 3815 3820 3825 Leu Pro Pro Lys Asn Ser Ile Asp Ala Phe Lys Leu Asn Ile Lys 3830 3835 3840 Leu Leu Gly Val Gly Gly Lys Pro Cys Ile Lys Val Ala Thr Val 3845 3850 3855 Gln Ser Lys Met Ser Asp Val Lys Cys Thr Ser Val Val Leu Leu 3860 3865 3870 Ser Val Leu Gln Gln Leu Arg Val Glu Ser Ser Ser Lys Leu Trp 3875 3880 3885 Ala Gln Cys Val Gln Leu Hes Asn Asp Ile Leu Leu Ala Lys Asp 3890 3895 3900 Thr Thr Glu Ala Phe Glu Lys Met Val Ser Leu Leu Ser Val Leu 3905 3910 3915 Leu Ser Met Gln Gly Ala Val Asp Ile Asn Lys Leu Cys Glu Glu 3920 3925 3930 Met Leu Asp Asn Arg Ala Thr Leu Gln Ala Ile Ala Ser Glu Phe 3935 3940 3945 Ser Ser Leu Pro Ser Tyr Ala Ala Phe Ala Thr Ala Gln Glu Ala 3950 3955 3960 Tyr Glu Gln Ala Val Ala Asn Gly Asp Ser Glu Val Val Leu Lys 3965 3970 3975 Lys Leu Lys Lys Ser Leu Asn Val Ala Lys Ser Glu Phe Asp Arg 3980 3985 3990 Asp Ala Ala Met Gln Arg Lys Leu Glu Lys Met Ala Asp Gln Ala 3995 4000 4005 Met Thr Gln Met Tyr Lys Gln Ala Arg Ser Glu Asp Lys Arg Ala 4010 4015 4020 Lys Val Thr Ser Ala Met Gln Thr Met Leu Phe Thr Met Leu Arg 4025 4030 4035 Lys Leu Asp Asn Asp Ala Leu Asn Asn Ile Ile Asn Asn Ala Arg 4040 4045 4050 Asp Gly Cys Val Pro Leu Asn Ile Ile Pro Leu Thr Thr Ala Ala 4055 4060 4065 Lys Leu Met Val Val Ile Pro Asp Tyr Asn Thr Tyr Lys Asn Thr 4070 4075 4080 Cys Asp Gly Thr Thr Phe Thr Tyr Ala Ser Ala Leu Trp Glu Ile 4085 4090 4095 Gln Gln Val Val Asp Ala Asp Ser Lys Ile Val Gln Leu Ser Glu 4100 4105 4110 Ile Ser Met Asp Asn Ser Pro Asn Leu Ala Trp Pro Leu Ile Val 4115 4120 4125 Thr Ala Leu Arg Ala Asn Ser Ala Val Lys Leu Gln Asn Asn Glu 4130 4135 4140 Leu Ser Pro Val Ala Leu Arg Gln Met Ser Cys Ala Ala Gly Thr 4145 4150 4155 Thr Gln Thr Ala Cys Thr Asp Asp Asn Ala Leu Ala Tyr Tyr Asn 4160 4165 4170 Thr Thr Lys Gly Gly Arg Phe Val Leu Ala Leu Leu Ser Asp Leu 4175 4180 4185 Gln Asp Leu Lys Trp Ala Arg Phe Pro Lys Ser Asp Gly Thr Gly 4190 4195 4200 Thr Ile Tyr Thr Glu Leu Glu Pro Pro Cys Arg Phe Val Thr Asp 4205 4210 4215 Thr Pro Lys Gly Pro Lys Val Lys Tyr Leu Tyr Phe Ile Lys Gly 4220 4225 4230 Leu Asn Asn Leu Asn Arg Gly Met Val Leu Gly Ser Leu Ala Ala 4235 4240 4245 Thr Val Arg Leu Gln Ala Gly Asn Ala Thr Glu Val Pro Ala Asn 4250 4255 4260 Ser Thr Val Leu Ser Phe Cys Ala Phe Ala Val Asp Ala Ala Lys 4265 4270 4275 Ala Tyr Lys Asp Tyr Leu Ala Ser Gly Gly Gln Pro Ile Thr Asn 4280 4285 4290 Cys Val Lys Met Leu Cys Thr Hes Thr Gly Thr Gly Gln Ala Ile 4295 4300 4305 Thr Val Thr Pro Glu Ala Asn Met Asp Gln Glu Ser Phe Gly Gly 4310 4315 4320 Ala Ser Cys Cys Leu Tyr Cys Arg Cys Hes Ile Asp Hes Pro Asn 4325 4330 4335 Pro Lys Gly Phe Cys Asp Leu Lys Gly Lys Tyr Val Gln Ile Pro 4340 4345 4350 Thr Thr Cys Ala Asn Asp Pro Val Gly Phe Thr Leu Lys Asn Thr 4355 4360 4365 Val Cys Thr Val Cys Gly Met Trp Lys Gly Tyr Gly Cys Ser Cys 4370 4375 4380 Asp Gln Leu Arg Glu Pro Met Leu Gln Ser Ala Asp Ala Gln Ser 4385 4390 4395 Phe Leu Asn Gly Phe Ala Val 4400 4405 <210> 17 <211> 1273 <212> PRT <213> SARS-CoV2 <220> <221> diferentes_características <222> (320)..(320) <223> Xaa puede ser cualquier aminoácido natural. <220> <221> diferentes_características <222> (709)..(709) <223> Xaa puede ser cualquier aminoácido natural. <400> 17 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ser Gln Cys Val 1 5 10 15 Asn Leu Thr Thr Arg Thr Gln Leu Pro Pro Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Hes Val Ser Gly Thr Asn Gly Thr Lys Arg Phe Asp 65 70 75 80 Asn Pro Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu 85 90 95 Lys Ser Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser 100 105 110 Lys Thr Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile 115 120 125 Lys Val Cys Glu Phe Gln Phe Cys Asn Asp Pro Phe Leu Gly Val Tyr 130 135 140 Tyr Hes Lys Asn Asn Lys Ser Trp Met Glu Ser Glu Phe Arg Val Tyr 145 150 155 160 Ser Ser Ala Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu 165 170 175 Met Asp Leu Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Arg Glu Phe 180 185 190 Val Phe Lys Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr 195 200 205 Pro Ile Asn Leu Val Arg Asp Leu Pro Gln Gly Phe Ser Ala Leu Glu 210 215 220 Pro Leu Val Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Thr 225 230 235 240 Leu Leu Ala Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser 245 250 255 Gly Trp Thr Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro 260 265 270 Arg Thr Phe Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala 275 280 285 Val Asp Cys Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys 290 295 300 Ser Phe Thr Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Xaa 305 310 315 320 Gln Pro Thr Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys 325 330 335 Pro Phe Gly Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala 340 345 350 Trp Asn Arg Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Val Leu 355 360 365 Tyr Asn Ser Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro 370 375 380 Thr Lys Leu Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe 385 390 395 400 Val Ile Arg Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly 405 410 415 Lys Ile Ala Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys 420 425 430 Val Ile Ala Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn 435 440 445 Tyr Asn Tyr Leu Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe 450 455 460 Glu Arg Asp Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys 465 470 475 480 Asn Gly Val Glu Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly 485 490 495 Phe Gln Pro Thr Asn Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val 500 505 510 Leu Ser Phe Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys 515 520 525 Lys Ser Thr Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn 530 535 540 Gly Leu Thr Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu 545 550 555 560 Pro Phe Gln Gln Phe Gly Arg Asp Ile Ala Asp Thr Thr Asp Ala Val 565 570 575 Arg Asp Pro Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe 580 585 590 Gly Gly Val Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val 595 600 605 Ala Val Leu Tyr Gln Gly Val Asn Cys Thr Glu Val Pro Val Ala Ile 610 615 620 Hes Ala Asp Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser 625 630 635 640 Asn Val Phe Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Hes Val 645 650 655 Asn Asn Ser Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala 660 665 670 Ser Tyr Gln Thr Gln Thr Asn Ser Pro Arg Arg Ala Arg Ser Val Ala 675 680 685 Ser Gln Ser Ile Ile Ala Tyr Thr Met Ser Leu Gly Ala Glu Asn Ser 690 695 700 Val Ala Tyr Ser Xaa Asn Ser Ile Ala Ile Pro Thr Asn Phe Thr Ile 705 710 715 720 Ser Val Thr Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val 725 730 735 Asp Cys Thr Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu 740 745 750 Leu Leu Gln Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr 755 760 765 Gly Ile Ala Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln 770 775 780 Val Lys Gln Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe 785 790 795 800 Asn Phe Ser Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser 805 810 815 Phe Ile Glu Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly 820 825 830 Phe Ile Lys Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp 835 840 845 Leu Ile Cys Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu 850 855 860 Leu Thr Asp Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly 865 870 875 880 Thr Ile Thr Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile 885 890 895 Pro Phe Ala Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr 900 905 910 Gln Asn Val Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn 915 920 925 Ser Ala Ile Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala 930 935 940 Leu Gly Lys Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn 945 950 955 960 Thr Leu Val Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val 965 970 975 Leu Asn Asp Ile Leu Ser Arg Leu Asp Lys Val Glu Ala Glu Val Gln 980 985 990 Ile Asp Arg Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val 995 1000 1005 Thr Gln Gln Leu Ile Arg Ala Ala Glu Ile Arg Val Ser Ala Asn 1010 1015 1020 Leu Ala Ala Thr Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys 1025 1030 1035 Arg Val Asp Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro 1040 1045 1050 Gln Ser Ala Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val 1055 1060 1065 Pro Ala Gln Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes 1070 1075 1080 Asp Gly Lys Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn 1085 1090 1095 Gly Thr Hes Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln 1100 1105 1110 Ile Ile Thr Thr Asp Asn Thr Phe Val Ser Gly Asn Cys Asp Val 1115 1120 1125 Val Ile Gly Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro 1130 1135 1140 Glu Leu Asp Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn 1145 1150 1155 Hes Thr Ser Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn 1160 1165 1170 Ala Ser Val Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu 1175 1180 1185 Val Ala Lys Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu 1190 1195 1200 Gly Lys Tyr Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu 1205 1210 1215 Gly Phe Ile Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met 1220 1225 1230 Leu Cys Cys Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys 1235 1240 1245 Ser Cys Gly Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro 1250 1255 1260 Val Leu Lys Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 18 <211> 29897 <212> ADN <213> SARS-CoV2 <220> <221> diferentes_características <222> (11288)..(11293) <223> n es a, c, g, ó t <220> <221> diferentes_características <222> (22278)..(22283) <223> n es a, c, g, ó t <220> <221> diferentes_características <222> (29836)..(29864) <223> n es a, c, g, ó t <400> 18 attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct 60 gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact 120 cacgcagtat aattaataac taattactgt cgttgacagg acacgagtaa ctcttctatc 180 ttctgcaggc tgcttacggt ttcgtccgtg ttgcagccga tcatcagcac atctaggttt 240 tgtccgggtg tgaccgaaag gtaagatgga gagccttgtc cctggtttca acgagaaaac 300 acacgtccaa ctcagtttgc ctgttttaca ggttcgcgac gtgctcgtac gtggctttgg 360 agactccgtg gaggaggtct tatcagaggc acgtcaacat cttaaagatg gcacttgtgg 420 cttagtagaa gttgaaaaag gcgttttgcc tcaacttgaa cagccctatg tgttcatcaa 480 acgttcggat gctcgaactg cacctcatgg tcatgttatg gttgagctgg tagcagaact 540 cgaaggcatt cagtacggtc gtagtggtga gacacttggt gtccttgtcc ctcatgtggg 600 cgaaatacca gtggcttacc gcaaggttct tcttcgtaag aacggtaata aaggagctgg 660 tggccatagt tacggcgccg atctaaagtc atttgactta ggcgacgagc ttggcactga 720 tccttatgaa gattttcaag aaaactggaa cactaaacat agcagtggtg ttacccgtga 780 actcatgcgt gagcttaacg gaggggcata cactcgctat gtcgataaca acttctgtgg 840 ccctgatggc taccctcttg agtgcattaa agaccttcta gcacgtgctg gtaaagcttc 900 atgcactttg tccgaacaac tggactttat tgacactaag aggggtgtat actgctgccg 960 tgaacatgag catgaaattg cttggtacac ggaacgttct gaaaagagct atgaattgca 1020 gacacctttt gaaattaaat tggcaaagaa atttgacatc ttcaatgggg aatgtccaaa 1080 ttttgtattt cccttaaatt ccataatcaa gactattcaa ccaagggttg aaaagaaaaa 1140 gcttgatggc tttatgggta gaattcgatc tgtctatcca gttgcgtcac caaatgaatg 1200 caaccaaatg tgcctttcaa ctctcatgaa gtgtgatcat tgtggtgaaa cttcatggca 1260 gacgggcgat tttgttaaag ccacttgcga attttgtggc actgagaatt tgactaaaga 1320 aggtgccact acttgtggtt acttacccca aaatgctgtt gttaaaattt attgtccagc 1380 atgtcacaat tcagaagtag gacctgagca tagtcttgcc gaataccata atgaatctgg 1440 cttgaaaacc attcttcgta agggtggtcg cactattgcc tttggaggct gtgtgttctc 1500 ttatgttggt tgccataaca agtgtgccta ttgggttcca cgtgctagcg ctaacatagg 1560 ttgtaaccat acaggtgttg ttggagaagg ttccgaaggt cttaatgaca accttcttga 1620 aatactccaa aaagagaaag tcaacatcaa tattgttggt gactttaaac ttaatgaaga 1680 gatcgccatt attttggcat ctttttctgc ttccacaagt gcttttgtgg aaactgtgaa 1740 aggtttggat tataaagcat tcaaacaaat tgttgaatcc tgtggtaatt ttaaagttac 1800 aaaaggaaaa gctaaaaaag gtgcctggaa tattggtgaa cagaaatcaa tactgagtcc 1860 tctttatgca tttgcatcag aggctgctcg tgttgtacga tcaattttct cccgcactct 1920 tgaaactgct caaaattctg tgcgtgtttt acagaaggcc gctataacaa tactagatgg 1980 aatttcacag tattcactga gactcattga tgctatgatg ttcacatctg atttggctac 2040 taacaatcta gttgtaatgg cctacattac aggtggtgtt gttcagttga cttcgcagtg 2100 gctaactaac atctttggca ctgtttatga aaaactcaaa cccgtccttg attggcttga 2160 agagaagttt aaggaaggtg tagagtttct tagagacggt tgggaaattg ttaaatttat 2220 ctcaacctgt gcttgtgaaa ttgtcggtgg acaaattgtc acctgtgcaa aggaaattaa 2280 ggagagtgtt cagacattct ttaagcttgt aaataaattt ttggctttgt gtgctgactc 2340 tatcattatt ggtggagcta aacttaaagc cttgaattta ggtgaaacat ttgtcacgca 2400 ctcaaaggga ttgtacagaa agtgtgttaa atccagagaa gaaactggcc tactcatgcc 2460 tctaaaagcc ccaaaagaaa ttatcttctt agagggagaa acacttccca cagaagtgtt 2520 aacagaggaa gttgtcttga aaactggtga tttacaacca ttagaacaac ctactagtga 2580 agctgttgaa gctccattgg ttggtacacc agtttgtatt aacgggctta tgttgctcga 2640 aatcaaagac acagaaaagt actgtgccct tgcacctaat atgatggtaa ctaacaatac 2700 cttcacactc aaaggcggtg caccaacaaa ggttactttt ggtgatgaca ctgtgataga 2760 agtgcaaggt tacaagagtg tgaatatcac ttttgaactt gatgaaagga ttgataaagt 2820 acttaatgag aagtgctctg cctatacagt tgaactcggt acagaagtaa atgagttcgc 2880 ctgtgttgtg gcagatgctg tcataaaaac tttgcaacca gtatctgaat tacttacacc 2940 actgggcatt gatttagatg agtggagtat ggctacatac tacttatttg atgagtctgg 3000 tgagtttaaa ttggcttcac atatgtattg ttctttttac cctccagatg aggatgaaga 3060 agaaggtgat tgtgaagaag aagagtttga gccatcaact caatatgagt atggtactga 3120 agatgattac caaggtaaac ctttggaatt tggtgccact tctgctgctc ttcaacctga 3180 agaagagcaa gaagaagatt ggttagatga tgatagtcaa caaactgttg gtcaacaaga 3240 cggcagtgag gacaatcaga caactactat tcaaacaatt gttgaggttc aacctcaatt 3300 agagatggaa cttacaccag ttgttcagac tattgaagtg aatagtttta gtggttattt 3360 aaaacttact gacaatgtat acattaaaaa tgcagacatt gtggaagaag ctaaaaaggt 3420 aaaaccaaca gtggttgtta atgcagccaa tgtttacctt aaacatggag gaggtgttgc 3480 aggagcctta aataaggcta ctaacaatgc catgcaagtt gaatctgatg attacatagc 3540 tactaatgga ccacttaaag tgggtggtag ttgtgtttta agcggacaca atcttgctaa 3600 acactgtctt catgttgtcg gcccaaatgt taacaaaggt gaagacattc aacttcttaa 3660 gagtgcttat gaaaatttta atcagcacga agttctactt gcaccattat tatcagctgg 3720 tatttttggt gctgacccta tacattcttt aagagtttgt gtagatactg ttcgcacaaa 3780 tgtctactta gctgtctttg ataaaaatct ctatgacaaa cttgtttcaa gctttttgga 3840 aatgaagagt gaaaagcaag ttgaacaaaa gatcgctgag attcctaaag aggaagttaa 3900 gccatttata actgaaagta aaccttcagt tgaacagaga aaacaagatg ataagaaaat 3960 caaagcttgt gttgaagaag ttacaacaac tctggaagaa actaagttcc tcacagaaaa 4020 cttgttactt tatattgaca ttaatggcaa tcttcatcca gattctgcca ctcttgttag 4080 tgacattgac atcactttct taaagaaaga tgctccatat atagtgggtg atgttgttca 4140 agagggtgtt ttaactgctg tggttatacc tactaaaaag gctggtggca ctactgaaat 4200 gttagcgaaa gctttgagaa aagtgccaac agacaattat ataaccactt acccgggtca 4260 gggtttaaat ggttacactg tagaggaggc aaagacagtg cttaaaaagt gtaaaagtgc 4320 cttttacatt ctaccatcta ttatctctaa tgagaagcaa gaaattcttg gaactgtttc 4380 ttggaatttg cgagaaatgc ttgcacatgc agaagaaaca cgcaaattaa tgcctgtctg 4440 tgtggaaact aaagccatag tttcaactat acagcgtaaa tataagggta ttaaaataca 4500 agagggtgtg gttgattatg gtgctagatt ttacttttac accagtaaaa caactgtagc 4560 gtcacttatc aacacactta acgatctaaa tgaaactctt gttacaatgc cacttggcta 4620 tgtaacacat ggcttaaatt tggaagaagc tgctcggtat atgagatctc tcaaagtgcc 4680 agctacagtt tctgtttctt cacctgatgc tgttacagcg tataatggtt atcttacttc 4740 ttcttctaaa acacctgaag aacattttat tgaaaccatc tcacttgctg gttcctataa 4800 agattggtcc tattctggac aatctacaca actaggtata gaatttctta agagaggtga 4860 taaaagtgta tattacacta gtaatcctac cacattccac ctagatggtg aagttatcac 4920 ctttgacaat cttaagacac ttctttcttt gagagaagtg aggactatta aggtgtttac 4980 aacagtagac aacattaacc tccacacgca agttgtggac atgtcaatga catatggaca 5040 acagtttggt ccaacttatt tggatggagc tgatgttact aaaataaaac ctcataattc 5100 acatgaaggt aaaacatttt atgttttacc taatgatgac actctacgtg ttgaggcttt 5160 tgagtactac cacacaactg atcctagttt tctgggtagg tacatgtcag cattaaatca 5220 cactaaaaat tggaaatacc cacaagttaa tggtttaact tctattaaat gggcagataa 5280 caactgttat cttgccactg cattgttaac actccaacaa atagagttga agtttaatcc 5340 acctgctcta caagatgctt attacagagc aagggctggt gaagctgcta acttttgtgc 5400 acttatctta gcctactgta ataagacagt aggtgagtta ggtgatgtta gagaaacaat 5460 gagttacttg tttcaacatg ccaatttaga ttcttgcaaa agagtcttga acgtggtgtg 5520 taaaacttgt ggacaacagc agacaaccct taagggtgta gaagctgtta tgtacatggg 5580 cacactttct tatgaacaat ttaagaaagg tgttcagata ccttgtacgt gtggtaaaca 5640 agctacaaaa tatctagtac aacaggagtc accttttgtt atgatgtcag caccacctgc 5700 tcagtatgaa cttaagcatg gtacatttac ttgtgctagt gagtacactg gtaattacca 5760 gtgtggtcac tataaacata taacttctaa agaaactttg tattgcatag acggtgcttt 5820 acttacaaag tcctcagaat acaaaggtcc tattacggat gttttctaca aagaaaacag 5880 ttacacaaca accataaaac cagttactta taaattggat ggtgttgttt gtacagaaat 5940 tgaccctaag ttggacaatt attataagaa agacaattct tatttcacag agcaaccaat 6000 tgatcttgta ccaaaccaac catatccaaa cgcaagcttc gataatttta agtttgtatg 6060 tgataatatc aaatttgctg atgatttaaa ccagttaact ggttacaaga aacctgcttc 6120 aagagagctt aaagttacat ttttccctga cttaaatggt gatgtggtgg ctattgatta 6180 taaacactac acaccctctt ttaagaaagg agctaaattg ttacataaac ctattgtttg 6240 gcatgttaac aatgcaacta ataaagccac gtataaacca aatacctggt gtatacgttg 6300 tctttggagc acaaaaccag ttgaaacatc aaattcgttt gatgtactga agtcagagga 6360 cgcgcaggga atggataatc ttgcctgcga agatctaaaa ccagtctctg aagaagtagt 6420 ggaaaatcct accatacaga aagacgttct tgagtgtaat gtgaaaacta ccgaagttgt 6480 aggagacatt atacttaaac cagcaaataa tagtttaaaa attacagaag aggttggcca 6540 cacagatcta atggctgctt atgtagacaa ttctagtctt actattaaga aacctaatga 6600 attatctaga gtattaggtt tgaaaaccct tgctactcat ggtttagctg ctgttaatag 6660 tgtcccttgg gatactatag ctaattatgc taagcctttt cttaacaaag ttgttagtac 6720 aactactaac atagttacac ggtgtttaaa ccgtgtttgt actaattata tgccttattt 6780 ctttacttta ttgctacaat tgtgtacttt tactagaagt acaaattcta gaattaaagc 6840 atctatgccg actactatag caaagaatac tgttaagagt gtcggtaaat tttgtctaga 6900 ggcttcattt aattatttga agtcacctaa tttttctaaa ctgataaata ttataatttg 6960 gtttttacta ttaagtgttt gcctaggttc tttaatmtac tcaaccgctg ctttaggtgt 7020 tttaatgtct aatttaggca tgccttctta ctgtactggt tacagagaag gctatttgaa 7080 ctctactaat gtcactattg caacctactg tactggttct ataccttgta gtgtttgtct 7140 tagtggttta gattctttag acacctatcc ttctttagaa actatacaaa ttaccatttc 7200 atcttttaaa tgggatttaa ctgcttttgg cttagttgca gagtggtttt tggcatatat 7260 tcttttcact aggtttttct atgtacttgg attggctgca atcatgcaat tgtttttcag 7320 ctattttgca gtacatttta ttagtaattc ttggcttatg tggttaataa ttaatcttgt 7380 acaaatggcc ccgatttcag ctatggttag aatgtacatc ttctttgcat cattttatta 7440 tgtatggaaa agttatgtgc atgttgtaga cggttgtaat tcatcaactt gtatgatgtg 7500 ttacaaacgt aatagagcaa caagagtcga atgtacaact attgttaatg gtgttagaag 7560 gtccttttat gtctatgcta atggaggtaa aggcttttgc aaactacaca attggaattg 7620 tgttaattgt gatacattct gtgctggtag tacatttatt agtgatgaag ttgcgagaga 7680 cttgtcacta cagtttaaaa gaccaataaa tcctactgac cagtcttctt acatcgttga 7740 tagtgttaca gtgaagaatg gttccatcca tctttacttt gataaagctg gtcaaaagac 7800 ttatgaaaga cattctctct ctcattttgt taacttagac aacctgagag ctaataacac 7860 taaaggttca ttgcctatta atgttatagt ttttgatggt aaatcaaaat gtgaagaatc 7920 atctgcaaaa tcagcgtctg tttactacag tcagcttatg tgtcaaccta tactgttact 7980 agatcaggca ttagtgtctg atgttggtga tagtgcggaa gttgcagtta aaatgtttga 8040 tgcttacgtt aatacgtttt catcaacttt taacgtacca atggaaaaac tcaaaacact 8100 agttgcaact gcagaagctg aacttgcaaa gaatgtgtcc ttagacaatg tcttatctac 8160 ttttatttca gcagctcggc aagggtttgt tgattcagat gtagaaacta aagatgttgt 8220 tgaatgtctt aaattgtcac atcaatctga catagaagtt actggcgata gttgtaataa 8280 ctatatgctc acctataaca aagttgaaaa catgacaccc cgtgaccttg gtgcttgtat 8340 tgactgtagt gcgcgtcata ttaatgcgca ggtagcaaaa agtcacaaca ttgctttgat 8400 atggaacgtt aaagatttca tgtcattgtc tgaacaacta cgaaaacaaa tacgtagtgc 8460 tgctaaaaag aataacttac cttttaagtt gacatgtgca actactagac aagttgttaa 8520 tgttgtaaca acaaagatag cacttaaggg tggtaaaatt gttaataatt ggttgaagca 8580 gttaattaaa gttacacttg tgttcctttt tgttgctgct attttctatt taataacacc 8640 tgttcatgtc atgtctaaac atactgactt ttcaagtgaa atcataggat acaaggctat 8700 tgatggtggt gtcactcgtg acatagcatc tacagatact tgttttgcta acaaacatgc 8760 tgattttgac acatggttta gccagcgtgg tggtagttat actaatgaca aagcttgccc 8820 attgattgct gcagtcataa caagagaagt gggttttgtc gtgcctggtt tgcctggcac 8880 gatattacgc acaactaatg gtgacttttt gcatttctta cctagagttt ttagtgcagt 8940 tggtaacatc tgttacacac catcaaaact tatagagtac actgactttg caacatcagc 9000 ttgtgttttg gctgctgaat gtacaatttt taaagatgct tctggtaagc cagtaccata 9060 ttgttatgat accaatgtac tagaaggttc tgttgcttat gaaagtttac gccctgacac 9120 acgttatgtg ctcatggatg gctctattat tcaatttcct aacacctacc ttgaaggttc 9180 tgttagagtg gtaacaactt ttgattctga gtactgtagg cacggcactt gtgaaagatc 9240 agaagctggt gtttgtgtat ctactagtgg tagatgggta cttaacaatg attattacag 9300 atctttacca ggagttttct gtggtgtaga tgctgtaaat ttatttacta atatgtttac 9360 accactaatt caacctattg gtgctttgga catatcagca tctatagtag ctggtggtat 9420 tgtagctatc gtagtaacat gccttgccta ctattttatg aggtttagaa gagcttttgg 9480 tgaatacagt catgtagttg cctttaatac tttactattc cttatgtcat tcactgtact 9540 ctgtttaaca ccagtttact cattcttacc tggtgtttat tctgttattt acttgtactt 9600 gacattttat cttactaatg atgtttcttt tttagcacat attcagtgga tggttatgtt 9660 cacaccttta gtacctttct ggataacaat tgcttatatc atttgtattt ccacaaagca 9720 tttctattgg ttctttagta attacctaaa gagacgtgta gtctttaatg gtgtttcctt 9780 tagtactttt gaagaagctg cgctgtgcac ctttttgtta aataaagaaa tgtatctaaa 9840 gttgcgtagt gatgtgctat tacctcttac gcaatataat agatacttag ctctttataa 9900 taagtacaag tattttagtg gagcaatgga tacaactagc tacagagaag ctgcttgttg 9960 tcatctcgca aaggctctca atgacttcag taactcaggt tctgatgttc tttaccaacc 10020 accacaaacc tctatcacct cagctgtttt gcagagtggt tttagaaaaa tggcattccc 10080 atctggtaaa gttgagggtt gtatggtaca agtaacttgt ggtacaacta cacttaacgg 10140 tctttggctt gatgacgtag tttactgtcc aagacatgtg atctgcacct ctgaagacat 10200 gcttaaccct aattatgaag atttactcat tcgtaagtct aatcataatt tcttggtaca 10260 ggctggtaat gttcaactca gggttattgg acattctatg caaaattgtg tacttaagct 10320 tagggttgat acagccaatc ctaagacacc taagtataag tttgttcgca ttcaaccagg 10380 acagactttt tcagtgttag cttgttacaa tggttcacca tctggtgttt accaatgtgc 10440 tatgaggccc aatttcacta ttaagggttc attccttaat ggttcatgtg gtagtgttgg 10500 ttttaacata gattatgact gtgtctcttt ttkttacatg caccatatgg aattaccaac 10560 tggagttcat gctggcacag acttagaagg taacttttat ggaccttttg ttgacaggca 10620 aacagcacaa gcagctggta cggacacaac tattacagtt aatgttttag cttggttgta 10680 cgctgctgtt ataaatggag acaggtggtt tctcaatcga tttaccacaa ctcttaatga 10740 ctttaacctt gtggctatga agtacaatta tgaacytcta acacaagacc atgttgacat 10800 actaggacct ctttctgctc aaactggaat tgccgtttta gatatgtgtg cttcattaaa 10860 agaattactg caaaatggta tgaatggacg taccatattg ggtagtgctt tattagaaga 10920 tgaatttaca ccttttgatg ttgttagaca atgctcaggt gttactttcc aaagtgcagt 10980 gaaaagaaca atcaagggta cacaccactg gttgttactc acaattttga cttcactttt 11040 agttttagtc cagagtactc aatggtcttt gttctttttt ttgtatgaaa atgccttttt 11100 accttttgct atgggtatta ttgctatgtc tgcttttgca atgatgtttg tcaaacataa 11160 gcatgcattt ctctgtttgt ttttgttacc ttctcttgcc actgtagctt attttaatat 11220 ggtctatatg cctgctagtt gggtgatgcg tattatgaca tggttggata tggttgatac 11280 tagtttgnnn nnnaagctaa aagactgtgt tatgtatgca tcagctgtag tgttactaat 11340 ccttatgaca gcaagaactg tgtatgatga tggtgctagg agagtgtgga cacttatgaa 11400 tgtcttgaca ctcgtttata aagtttatta tggtaatgct ttagatcaag ccatttccat 11460 gtgggctctt ataatctctg ttacttctaa ctactcaggt gtagttacaa ctgtcatgtt 11520 tttggccaga ggtattgttt ttatgtgtgt tgagtattgc cctattttct tcataactgg 11580 taatacactt cagtgtataa tgctagttta ttgtttctta ggctattttt gtacttgtta 11640 ctttggcctc ttttgtttac tcaaccgcta ctttagactg actcttggtg tttatgatta 11700 cttagtttct acacaggagt ttagatatat gaattcacag ggactaytcc cacccaagaa 11760 tagcatagat gccttcaaac tcaacattaa attgttgggt gttggtggca aaccttgtat 11820 caaagtagcc actgtacagt ctaaaatgtc agatgtaaag tgcacatcag tagtcttact 11880 ctcagttttg caacaactca gagtagaatc atcatctaaa ttgtgggctc aatgtgtcca 11940 gttacacaat gacattctct tagctaaaga tactactgaa gcctttgaaa aaatggtttc 12000 actactttct gttttgcttt ccatgcaggg tgctgtagac ataaacaagc tttgtgaaga 12060 aatgctggac aacagggcaa ccttacaagc tatagcctca gagtttagtt cccttccatc 12120 atatgcagct tttgctactg ctcaagaagc ttatgagcag gctgttgcta atggtgattc 12180 tgaagttgtt cttaaaaagt tgaagaagtc tttgaatgtg gctaaatctg aatttgaccg 12240 tgatgcagcc atgcaacgta agttggaaaa gatggctgat caagctatga cccaaatgta 12300 taaacaggct agatctgagg acaagagggc aaaagttact agtgctatgc agacaatgct 12360 tttcactatg cttagaaagt tggataatga tgcactcaac aacattatca acaatgcaag 12420 agatggttgt gttcccttga acataatacc tcttacaaca gcagccaaac taatggttgt 12480 cataccagac tataacacat ataaaaatac gtgtgatggt acaacattta cttatgcatc 12540 agcattgtgg gaaatccaac aggttgtaga tgcagatagt aaaattgttc aacttagtga 12600 aattagtatg gacaattcac ctaatttagc atggcctctt attgtaacag ctttaagggc 12660 caattctgct gtcaaattac agaataatga gcttagtcct gttgcactac gacagatgtc 12720 ttgtgctgcc ggtactacac aaactgcttg cactgatgac aatgcgttag cttactacaa 12780 cacaacaaag ggaggtaggt ttgtacttgc actgttatcc gatttacagg atttgaaatg 12840 ggctagattc cctaagagtg atggaactgg tactatctat acagaactgg aaccaccttg 12900 taggtttgtt acagacacac ctaaaggtcc taaagtgaag tatttatact ttattaaagg 12960 attaaacaac ctaaatagag gtatggtact tggtagttta gctgccacag tacgtctaca 13020 agctggtaat gcaacagaag tgcctgccaa ttcaactgta ttatctttct gtgcttttgc 13080 tgtagatgct gctaaagctt acaaagatta tctagctagt gggggacaac caatcactaa 13140 ttgtgttaag atgttgtgta cacacactgg tactggtcag gcaataacag ttacaccgga 13200 agccaatatg gatcaagaat cctttggtgg tgcatcgtgt tgtctgtact gccgttgcca 13260 catagatcat ccaaatccta aaggattttg tgacttaaaa ggtaagtatg tacaaatacc 13320 tacaacttgt gctaatgacc ctgtgggttt tacacttaaa aacacagtct gtaccgtctg 13380 cggtatgtgg aaaggttatg gctgtagttg tgatcaactc cgcgaaccca tgcttcagtc 13440 agctgatgca caatcgtttt taaacgggtt tgcggtgtaa gtgcagcccg tcttacaccg 13500 tgcggcacag gcactagtac tgatgtcgta tacagggctt ttgacatcta caatgataaa 13560 gtagctggtt ttgctaaatt cctaaaaact aattgttgtc gcttccaaga aaaggacgaa 13620 gatgacaatt taattgattc ttactttgta gttaagagac acactttctc taactaccaa 13680 catgaagaaa caatttataa tttacttaag gattgtccag ctgttgctaa acatgacttc 13740 tttaagttta gaatagacgg tgacatggta ccacatatat cacgtcaacg tcttactaaa 13800 tacacaatgg cagacctcgt ctatgcttta aggcattttg atgaaggtaa ttgtgacaca 13860 ttaaaagaaa tacttgtcac atacaattgt tgtgatgatg attatttcaa taaaaaggac 13920 tggtatgatt ttgtagaaaa cccagatata ttacgcgtat acgccaactt aggtgaacgt 13980 gtacgccaag ctttgttaaa aacagtacaa ttctgtgatg ccatgcgaaa tgctggtatt 14040 gttggtgtac tgacattaga taatcaagat ctcaatggta actggtatga tttcggtgat 14100 ttcatacaaa ccacgccagg tagtggagtt cctgttgtag attcttatta ttcattgtta 14160 atgcctatat taaccttgac cagggcttta actgcagagt cacatgttga cactgactta 14220 acaaagcctt acattaagtg ggatttgtta aaatatgact tcacggaaga gaggttaaaa 14280 ctctttgacc gttattttaa atattgggat cagacatacc acccaaattg tgttaactgt 14340 ttggatgaca gatgcattct gcattgtgca aactttaatg ttttattctc tacagtgttc 14400 ccacttacaa gttttggacc actagtgaga aaaatatttg ttgatggtgt tccatttgta 14460 gtttcaactg gataccactt cagagagcta ggtgttgtac ataatcagga tgtaaactta 14520 catagctcta gacttagttt taaggaatta cttgtgtatg ctgctgaccc tgctatgcac 14580 gctgcttctg gtaatctatt actagataaa cgcactacgt gcttttcagt agctgcactt 14640 actaacaatg ttgcttttca aactgtcaaa cccggtaatt ttaacaaaga cttctatgac 14700 tttgctgtgt ctaagggttt ctttaaggaa ggaagttctg ttgaattaaa acacttcttc 14760 tttgctcagg atggtaatgc tgctatcagc gattatgact actatcgtta taatctacca 14820 acaatgtgtg atatcagaca actactattt gtagttgaag ttgttgataa gtactttgat 14880 tgttacgatg gtggctgtat taatgctaac caagtcatcg tcaacaacct agacaaatca 14940 gctggttttc catttaataa atggggtaag gctagacttt attatgattc aatgagttat 15000 gaggatcaag atgcactttt cgcatataca aaacgtaatg tcatccctac tataactcaa 15060 atgaatctta agtatgccat tagtgcaaag aatagagctc gcaccgtagc tggtgtctct 15120 atctgtagta ctatgaccaa tagacagttt catcaaaaat tattgaaatc aatagccgcc 15180 actagaggag ctactgtagt aattggaaca agcaaattct atggtggttg gcacaacatg 15240 ttaaaaactg tttatagtga tgtagaaaac cctcacctta tgggttggga ttatcctaaa 15300 tgtgatagag ccatgcctaa catgcttaga attatggcct cacttgttct tgctcgcaaa 15360 catacaacgt gttgtagctt gtcacaccgt ttctatagat tagctaatga gtgtgctcaa 15420 gtattgagtg aaatggtcat gtgtggcggt tcactatatg ttaaaccagg tggaacctca 15480 tcaggagatg ccacaactgc ttatgctaat agtgttttta acatttgtca agctgtcacg 15540 gccaatgtta atgcactttt atctactgat ggtaacaaaa ttgccgataa gtatgtccgc 15600 aatttacaac acagacttta tgagtgtctc tatagaaata gagatgttga cacagacttt 15660 gtgaatgagt tttacgcata tttgcgtaaa catttctcaa tgatgatact ctctgacgat 15720 gctgttgtgt gtttcaatag cacttatgca tctcaaggtc tagtggctag cataaagaac 15780 tttaagtcag ttctttatta tcaaaacaat gtttttatgt ctgaagcaaa atgttggact 15840 gagactgacc ttactaaagg acctcatgaa ttttgctctc aacatacaat gctagttaaa 15900 cagggtgatg attatgtgta ccttccttac ccagatccat caagaatcct aggggccggc 15960 tgttttgtag atgatatcgt aaaaacagat ggtacactta tgattgaacg gttcgtgtct 16020 ttagctatag atgcttaccc acttactaaa catcctaatc aggagtatgc tgatgtcttt 16080 catttgtact tacaatacat aagaaagcta catgatgagt taacaggaca catgttagac 16140 atgtattctg ttatgcttac taatgataac acttcaaggt attgggaacc tgagttttat 16200 gaggctatgt acacaccgca tacagtctta caggctgttg gggcttgtgt tctttgcaat 16260 tcacagactt cattaagatg tggtgcttgc atacgtagac cattcttatg ttgtaaatgc 16320 tgttacgacc atgtcatatc aacatcacat aaattagtct tgtctgttaa tccgtatgtt 16380 tgcaatgctt caggttgtga tgtcacagat gtgactcaac tttacttagg aggtatgagc 16440 tattattgta aatcacataa accacccatt agttttccat tgtgtgctaa tggacaagtt 16500 tttggtttat ataaaaatac atgtgttggt agcgataatg ttactgactt taatgcaatt 16560 gcaacatgtg actggacaaa tgctggtgat tacattttag ctaacacctg tactgaaaga 16620 ctcaagcttt ttgcagcaga aacgctcaaa gctactgagg agacatttaa actgtcttat 16680 ggtattgcta ctgtacgtga agtgctgtct gacagagaat tacatctttc atgggaagtt 16740 ggtaaaccta gaccaccact taaccgaaat tatgtcttta ctggttatcg tgtaactaaa 16800 aacagtaaag tacaaatagg agagtacacc tttgaaaaag gtgactatgg tgatgctgtt 16860 gtttaccgag gtacaacaac ttacaaatta aatgttggtg attattttgt gctgacatca 16920 catacagtaa tgccattaag tgcacctaca ctagtgccac aagagcacta tgttagaatt 16980 actggcttat acccaacact caatatctca gatgagtttt ctagcaatgt tgcaaattat 17040 caaaaggttg gtatgcaaaa gtattctaca ctccagggac cacctggtac tggtaagagt 17100 cattttgcta ttggcctagc tctctactac ccttctgctc gcatagtgta tacagcttgc 17160 tctcatgccg ctgttgatgc actatgtgag aaggcattaa aatatttgcc tatagataaa 17220 tgtagtagaa ttatacctgc acgtgctcgt gtagagtgtt ttgataaatt caaagtgaat 17280 tcaacattag aacagtatgt cttttgtact gtaaatgcat tgcctgagac gacagcagat 17340 atagttgtct ttgatgaaat ttcaatggcc acaaattatg atttgagtgt tgtcaatgcc 17400 agattacgtg ctaagcacta tgtgtacatt ggcgaccctg ctcaattacc tgcaccacgc 17460 acattgctaa ctaagggcac actagaacca gaatatttca attcagtgtg tagacttatg 17520 aaaactatag gtccagacat gttcctcgga acttgtcggc gttgtcctgc tgaaattgtt 17580 gacactgtga gtgctttggt ttatgataat aagcttaaag cacataaaga caaatcagct 17640 caatgcttta aaatgtttta taagggtgtt atcacgcatg atgtttcatc tgcaattaac 17700 aggccacaaa taggcgtggt aagagaattc cttacacgta accctgcttg gagaaaagct 17760 gtctttattt caccttataa ttcacagaat gctgtagcct caaagatttt gggactacca 17820 actcaaactg ttgattcatc acagggctca gaatatgact atgtcatatt cactcaaacc 17880 actgaaacag ctcactcttg taatgtaaac agatttaatg ttgctattac cagagcaaaa 17940 gtaggcatac tttgcataat gtctgataga gacctttatg acaagttgca atttacaagt 18000 cttgaaattc cacgtaggaa tgtggcaact ttacaagctg aaaatgtaac aggactcttt 18060 aaagattgta gtaaggtaat cactgggtta catcctacac aggcacctac acacctcagt 18120 gttgacacta aattcaaaac tgaaggttta tgtgttgaca tacctggcat acctaaggac 18180 atgacctata gaagactcat ctctatgatg ggttttaaaa tgaattatca agttaatggt 18240 taccctaaca tgtttatcac ccgcgaagaa gctataagac atgtacgtgc atggattggc 18300 ttcgatgtcg aggggtgtca tgctactaga gaagctgttg gtaccaattt acctttacag 18360 ctaggttttt ctacaggtgt taacctagtt gctgtaccta caggttatgt tgatacacct 18420 aataatacag atttttccag agttagtgct aaaccaccgc ctggagatca atttaaacac 18480 ctcataccac ttatgtacaa aggacttcct tggaatgtag tgcgtataaa gattgtacaa 18540 atgttaagtg acacacttaa aaatctctct gacagagtcg tatttgtctt atgggcacat 18600 ggctttgagt tgacatctat gaagtatttt gtgaaaatag gacctgagcg cacctgttgt 18660 ctatgtgata gacgtgccac atgcttttcc actgcttcag acacttatgc ctgttggcat 18720 cattctattg gatttgatta cgtctataat ccgtttatga ttgatgttca acaatggggt 18780 tttacaggta acctacaaag caaccatgat ctgtattgtc aagtccatgg taatgcacat 18840 gtagctagtt gtgatgcaat catgactagg tgtctagctg tccacgagtg ctttgttaag 18900 cgtgttgact ggactattga atatcctata attggtgatg aactgaagat taatgcggct 18960 tgtagaaagg ttcaacacat ggttgttaaa gctgcattat tagcagacaa attcccagtt 19020 cttcacgaca ttggtaaccc taaagctatt aagtgtgtac ctcaagctga tgtagaatgg 19080 aagttctatg atgcacagcc ttgtagtgac aaagcttata aaatagaaga attattctat 19140 tcttatgcca cacattctga caaattcaca gatggtgtat gcctattttg gaattgcaat 19200 gtcgatagat atcctgctaa ttccattgtt tgtagatttg acactagagt gctatctaac 19260 cttaacttgc ctggttgtga tggtggcagt ttgtatgtaa ataaacatgc attccacaca 19320 ccagcttttg ataaaagtgc ttttgttaat ttaaaacaat taccattttt ctattactct 19380 gacagtccat gtgagtctca tggaaaacaa gtagtgtcag atatagatta tgtaccacta 19440 aagtctgcta cgtgtataac acgttgcaat ttaggtggtg ctgtctgtag acatcatgct 19500 aatgagtaca gattgtatct cgatgcttat aacatgatga tctcagctgg ctttagcttg 19560 tgggtttaca aacaatttga tacttataac ctctggaaca cttttacaag acttcagagt 19620 ttagaaaatg tggcttttaa tgttgtaaat aagggacact ttgatggaca acagggtgaa 19680 gtaccagttt ctatcattaa taacactgtt tacacaaaag ttgatggtgt tgatgtagaa 19740 ttgtttgaaa ataaaacaac attacctgtt aatgtagcat ttgagctttg ggctaagcgc 19800 aacattaaac cagtaccaga ggtgaaaata ctcaataatt tgggtgtgga cattgctgct 19860 aatactgtga tctgggacta caaaagagat gctccagcac atatatctac tattggtgtt 19920 tgttctatga ctgacatagc caagaaacca actgaaacga tttgtgcacc actcactgtc 19980 ttttttgatg gtagagttga tggtcaagta gacttattta gaaatgcccg taatggtgtt 20040 cttattacag aaggtagtgt taaaggttta caaccatctg taggtcccaa acaagctagt 20100 cttaatggag tcacattaat tggagaagcc gtaaaaacac agttcaatta ttataagaaa 20160 gttgatggtg ttgtccaaca attacctgaa acttacttta ctcagagtag aaatttacaa 20220 gaatttaaac ccaggagtca aatggaaatt gatttcttag aattagctat ggatgaattc 20280 attgaacggt ataaattaga aggctatgcc ttcgaacata tcgtttatgg agattttagt 20340 catagtcagt taggtggttt acatctactg attggactag ctaaacgttt taaggaatca 20400 ccttttgaat tagaagattt tattcctatg gacagtacag ttaaaaacta tttcataaca 20460 gatgcgcaaa caggttcatc taagtgtgtg tgttctgtta ttgatttatt acttgatgat 20520 tttgttgaaa taataaaatc ccaagattta tctgtagttt ctaaggttgt caaagtgact 20580 attgactata cagaaatttc atttatgctt tggtgtaaag atggccatgt agaaacattt 20640 tacccaaaat tacaatctag tcaagcgtgg caaccgggtg ttgctatgcc taatctttac 20700 aaaatgcaaa gaatgctatt agaaaagtgt gaccttcaaa attatggtga tagtgcaaca 20760 ttacctaaag gcataatgat gaatgtcgca aaatatactc aactgtgtca atatttaaac 20820 acattaacat tagctgtacc ctataatatg agagttatac attttggtgc tggttctgat 20880 aaaggagttg caccaggtac agctgtttta agacagtggt tgcctacggg tacgctgctt 20940 gtcgattcag atcttaatga ctttgtctct gatgcagatt caactttgat tggtgattgt 21000 gcaactgtac atacagctaa taaatgggat ctcattatta gtgatatgta cgaccctaag 21060 actaaaaatg ttacaaaaga aaatgactct aaagagggtt ttttcactta catttgtggg 21120 tttatacaac aaaagctagc tcttggaggt tccgtggcta taaagataac agaacattct 21180 tggaatgctg atctttataa gctcatggga cacttcgcat ggtggacagc ctttgttact 21240 aatgtgaatg cgtcatcatc tgaagcattt ttaattggat gtaattatct tggcaaacca 21300 cgcgaacaaa tagatggtta tgtcatgcat gcaaattaca tattttggag gaatacaaat 21360 ccaattcagt tgtcttccta ttctttattt gacatgagta aatttcccct taaattaagg 21420 ggtactgctg ttatgtcttt aaaagaaggt caaatcaatg atatgatttt atctcttctt 21480 agtaaaggta gacttataat tagagaaaac aacagagttg ttatttctag tgatgttctt 21540 gttaacaact aaacgaacaa tgtttgtttt tcttgtttta ttgccactag tctctagtca 21600 gtgtgttaat cttacaacca gaactcaatt accccctgca tacactaatt ctttcacacg 21660 tggtgtttat taccctgaca aagttttcag atcctcagtt ttacattcaa ctcaggactt 21720 gttcttacct ttcttttcca atgttacttg gttccatgct atacatgtct ctgggaccaa 21780 tggtactaag aggtttgcta accctgtcct accatttaat gatggtgttt attttgcttc 21840 cactgagaag tctaacataa taagaggctg gatttttggt actactttag attcgaagac 21900 ccagtcccta cttattgtta ataacgctac taatgttgtt attaaagtct gtgaatttca 21960 attttgtaat gatccatttt tgggtgttta ttaccacaaa aacaacaaaa gttggatgga 22020 aagtgagttc agagtttatt ctagtgcgaa taattgcact tttgaatatg tctctcagcc 22080 ttttcttatg gaccttgaag gaaaacaggg taatttcaaa aatcttaggg aatttgtgtt 22140 taagaatatt gatggttatt ttaaaatata ttctaagcac acgcctatta atttagtgcg 22200 tggtctccct cagggttttt cggctttaga accattggta gatttgccaa taggtattaa 22260 catcactagg tttcaaannn nnnctttaca tagaagttat ttgactcctg gtgattcttc 22320 ttcaggttgg acagctggtg ctgcagctta ttatgtgggt tatcttcaac ctaggacttt 22380 tctattaaaa tataatgaaa atggaaccat tacagatgct gtagactgtg cacttgaccc 22440 tctctcagaa acaaagtgta cgttgaaatc cttcactgta gaaaaaggaa tctatcaaac 22500 ttctaacttt agagtccaac caacagaatc tattgttaga tttcctaata ttacaaactt 22560 gtgccctttt ggtgaagttt ttaacgccac cagatttgca tctgtttatg cttggaacag 22620 gaagagaatc agcaactgtg ttgctgatta ttctgtccta tataattccg catcattttc 22680 cacttttaag tgttatggag tgtctcctac taaattaaat gatctctgct ttactaatgt 22740 ctatgcagat tcatttgtaa ttagaggtga tgaagtcaga caaatcgctc cagggcaaac 22800 tggaaatatt gctgattata attataaatt accagatgat tttacaggct gcgttatagc 22860 ttggaattct aacaatcttg attctaaggt tggtggtaat tataattacc tgtatagatt 22920 gtttaggaag tctaatctca aaccttttga gagagatatt tcaactgaaa tctatcaggc 22980 cggtagcaca ccttgtaatg gtgttaaagg ttttaattgt tactttcctt tacaatcata 23040 tggtttccaa cccacttatg gtgttggtta ccaaccatac agagtagtag tactttcttt 23100 tgaacttcta catgcaccag caactgtttg tggacctaaa aagtctacta atttggttaa 23160 aaacaaatgt gtcaatttca acttcaatgg tttaacaggc acaggtgttc ttactgagtc 23220 taacaaaaag tttctgcctt tccaacaatt tggcagagac attgctgaca ctactgatgc 23280 tgtccgtgat ccacagacac ttgagattct tgacattaca ccatgttctt ttggtggtgt 23340 cagtgttata acaccaggaa caaatacttc taaccaggtt gctgttcttt atcagggtgt 23400 taactgcaca gaagtccctg ttgctattca tgcagatcaa cttactccta cttggcgtgt 23460 ttattctaca ggttctaatg tttttcaaac acgtgcaggc tgtttaatag gggctgaaca 23520 tgtcaacaac tcatatgagt gtgacatacc cattggtgca ggtatatgcg ctagttatca 23580 gactcagact aattctcctc ggcgggcacg tagtgtagct agtcaatcca tcattgccta 23640 cactatgtca cttggtgtag aaaattcagt tgcttactct aataactcta ttgccatacc 23700 cacaaatttt actattagtg ttaccacaga aattctacca gtgtctatga ccaagacatc 23760 agtagattgt acaatgtaca tttgtggtga ttcaactgaa tgcagcaatc ttttgttgca 23820 atatggcagt ttttgtacac aattaaaccg tgctttaact ggaatagctg ttgaacaaga 23880 caaaaacacc caagaagttt ttgcacaagt caaacaaatt tacaaaacac caccaattaa 23940 agattttggt ggttttaatt tttcacaaat attaccagat ccatcaaaac caagcaagag 24000 gtcatttatt gaagatctac ttttcaacaa agtgacactt gcagatgctg gcttcatcaa 24060 acaatatggt gattgccttg gtgatattgc tgctagagac ctcatttgtg cacaaaagtt 24120 taacggcctt actgttttgc cacctttgct cacagatgaa atgattgctc aatacacttc 24180 tgcactgtta gcgggtacaa tcacttctgg ttggaccttt ggtgcaggtg ctgcattaca 24240 aataccattt gctatgcaaa tggcttatag gtttaatggt attggagtta cacagaatgt 24300 tctctatgag aaccaaaaat tgattgccaa ccaatttaat agtgctattg gcaaaattca 24360 agactcactt tcttccacag caagtgcact tggaaaactt caagatgtgg tcaaccaaaa 24420 tgcacaagct ttaaacacgc ttgttaaaca acttagctcc aattttggtg caatttcaag 24480 tgttttaaat gatatccttt cacgtcttga caaagttgag gctgaagtgc aaattgatag 24540 gttgatcaca ggcagacttc aaagtttgca gacatatgtg actcaacaat taattagagc 24600 tgcagaaatc agagcttctg ctaatcttgc tgctactaaa atgtcagagt gtgtacttgg 24660 acaatcaaaa agagttgatt tttgtggaaa gggctatcat cttatgtcct tccctcagtc 24720 agcacctcat ggtgtagtct tcttgcatgt gacttatgtc cctgcacaag aaaagaactt 24780 cacaactgct cctgccattt gtcatgatgg aaaagcacac tttcctcgtg aaggtgtctt 24840 tgtttcaaat ggcacacact ggtttgtaac acaaaggaat ttttatgaac cacaaatcat 24900 tactacagac aacacatttg tgtctggtaa ctgtgatgtt gtaataggaa ttgtcaacaa 24960 cacagtttat gatcctttgc aacctgaatt agactcattc aaggaggagt tagataaata 25020 ttttaagaat catacatcac cagatgttga tttaggtgac atctctggca ttaatgcttc 25080 agttgtaaac attcaaaaag aaattgaccg cctcaatgag gttgccaaga atttaaatga 25140 atctctcatc gatctccaag aacttggaaa gtatgagcag tatataaaat ggccatggta 25200 catttggcta ggttttatag ctggcttgat tgccatagta atggtgacaa ttatgctttg 25260 ctgtatgacc agttgctgta gttgtctcaa gggctgttgt tcttgtggat cctgctgcaa 25320 atttgatgaa gacgactctg agccagtgct caaaggagtc aaattacatt acacataaac 25380 gaacttatgg atttgtttat gagaatcttc acaattggaa ctgtaacttt gaagcaaggt 25440 gaaatcaagg atgctactcc ttcagatttt gttcgcgcta ctgcaacgat accgatacaa 25500 gcctcactcc ctttcggatg gcttattgtt ggcgttgcac ttcttgctgt ttttcatagc 25560 gcttccaaaa tcataaccct caaaaagaga tggcaactag cactctccaa gggtgttcac 25620 tttgtttgca acttgctgtt gttgtttgta acagtttact cacacctttt gctcgttgct 25680 gctggccttg aagccccttt tctctatctt tatgctttag tctacttctt gcagagtata 25740 aactttgtaa gaataataat gaggctttgg ctttgctgga aatgccgttc caaaaaccca 25800 ttactttatg atgccaacta ttttctttgc tggcatacta attgttacga ctattgtata 25860 ccttacaata gtgtaacttc ttcaattgtc attactttag gtgatggcac aacaagtcct 25920 atttctgaac atgactacca gattggtggt tatactgaaa aatgggaatc tggagtaaaa 25980 gactgtgttg tattacacag ttacttcact tcagactatt accagctgta ctcaactcaa 26040 ttgagtacag acactggtgt tgaacatgtt accttcttca tctacaataa aattgttgat 26100 gagcctgaag aacatgtcca aattcacaca atcgacggtt catccggagt tgttaatcca 26160 gtaatggaac caatttatga tgaaccgacg acgactacta gcgtgccttt gtaagcacaa 26220 gctgatgagt acgaacttat gtactcattc gtttcggaag agacaggtac gttaatagtt 26280 aatagcgtac ttctttttct tgctttcgtg gtattcttgc tagttacact agccatcctt 26340 actgcgcttc gattgtgtgc gtactgctgc aatattgtta acgtgagtct tgtaaaacct 26400 tctttttacg tttactctcg tgttaaaaat ctgaattctt ctagagttct tgatcttctg 26460 gtctaaacga actaaatatt atattagttt ttctgtttgg aactttaatt ttagccatgg 26520 cagattccaa cggtactatt accgttgaag agcttaaaaa gctccttgaa caatggaacc 26580 tagtaatagg tttcctattc cttacatgga tttgtcttct acaatttgcc tatgccaaca 26640 ggaataggtt tttgtatata attaagttaa ttttcctctg gctgttatgg ccagtaactt 26700 tagcttgttt tgtgcttgct gctgtttaca gaataaattg gatcaccggt ggaattgcta 26760 tcgcaatggc ttgtcttgta ggcttgatgt ggctcagcta cttcattgct tctttcagac 26820 tgtttgcgcg tacgcgttcc atgtggtcat tcaatccaga aactaacatt cttctcaacg 26880 tgccactcca tggcactatt ctgaccagac cgcttctaga aagtgaactc gtaatcggag 26940 ctgtgatcct tcgtggacat cttcgtattg ctggacacca tctaggacgc tgtgacatca 27000 aggacctgcc taaagaaatc actgttgcta catcacgaac gctttcttat tacaaattgg 27060 gagcttcgca gcgtgtagca ggtgactcag gttttgctgc atacagtcgc tacaggattg 27120 gcaactataa attaaacaca gaccattcca gtagcagtga caatattgct ttgcttgtac 27180 agtaagcgac aacagatgtt tcatctcgtt gactttcagg ttactatagc agagatatta 27240 ctaattatta tgaggacttt taaagtttcc atttggaatc ttgattacat cataaacctc 27300 ataattaaaa atttatctaa gtcactaact gagaataaat attctcaatt agatgaagag 27360 caaccaatgg agattgatta aacgaacatg aaaattattc ttttcttggc actgataaca 27420 ctcgctactt gtgagcttta tcactaccaa gagtgtgtta gaggtacaac agtactttta 27480 aaagaacctt gctcttctgg aacatacgag ggcaattcac catttcatcc tctagctgat 27540 aacaaatttg cactgacttg ctttagcact caatttgctt ttgcttgtcc tgacggcgta 27600 aaacacgtct atcagttacg tgccagatca gtttcaccta aactgttcat cagacaagag 27660 gaagttcaag aactttactc tccaattttt cttattgttg cggcaatagt gtttataaca 27720 ctttgcttca cactcaaaag aaagacagaa tgattgaact ttcattaatt gacttctatt 27780 tgtgcttttt agcctttctg ctattccttg ttttaattat gcttattatc ttttggttct 27840 cacttgaact gcaagatcat aatgaaactt gtcacgccta aacgaacatg aaatttcttg 27900 ttttcttagg aatcatcaca actgtagctg catttcacca agaatgtagt ttacagtcat 27960 gtactcaaca tcaaccatat gtagttgatg acccgtgtcc tattcacttc tattctaaat 28020 ggtatattag agtaggagct agaaaatcag cacctttaat tgaattgtgc gtggatgagg 28080 ctggttctaa atcacccatt cagtacatcg atatcggtaa ttatacagtt tcctgtttac 28140 cttttacaat taattgccag gaacctaaat tgggtagtct tgtagtgcgt tgttcgttct 28200 atgaagactt tttagagtat catgacgttc gtgttgtttt agattttatc taaacgaaca 28260 aactaaaatg tctgataatg gaccccaaaa tcagcgaaat gcaccccgca ttacgtttgg 28320 tggaccctca gattcaactg gcagtaacca gaatggagaa cgcagtgggg cgcgatcaaa 28380 acaacgtcgg ccccaaggtt tacccaataa tactgcgtct tggttcaccg ctctcactca 28440 acatggcaag gaagacctta aattccctcg aggacaaggc gttccaatta acaccaatag 28500 cagtccagat gaccaaattg gctactaccg aagagctacc agacgaattc gtggtggtga 28560 cggtaaaatg aaagatctca gtccaagatg gtatttctac tacctaggaa ctgggccaga 28620 agctggactt ccctatggtg ctaacaaaga cggcatcata tgggttgcaa ctgagggagc 28680 cttgaataca ccaaaagatc acattggcac ccgcaatcct gctaacaatg ctgcaatcgt 28740 gctacaactt cctcaaggaa caacattgcc aaaaggcttc tacgcagaag ggagcagagg 28800 cggcagtcaa gcctcttctc gttcctcatc acgtagtcgc aacagttcaa gaaattcaac 28860 tccaggcagc agtaggggaa tttctcctgc tagaatggct ggcaatggcg gtgatgctgc 28920 tcttgctttg ctgctgcttg acagattgaa ccagcttgag agcaaaatgt ctggtaaagg 28980 ccaacaacaa caaggccaaa ctgtcactaa gaaatctgct gctgaggctt ctaagaagcc 29040 tcggcaaaaa cgtactgcca ctaaagcata caatgtaaca caagctttcg gcagacgtgg 29100 tccagaacaa acccaaggaa attttgggga ccaggaacta atcagacaag gaactgatta 29160 caaacattgg ccgcaaattg cacaatttgc ccccagcgct tcagcgttct tcggaatgtc 29220 gcgcattggc atggaagtca caccttcggg aacgtggttg acctacacag gtgccatcaa 29280 attggatgac aaagatccaa atttcaaaga tcaagtcatt ttgctgaata agcatattga 29340 cgcatacaaa acattcccac caacagagcc taaaaaggac aaaaagaaga aggctgatga 29400 aactcaagcc ttaccgcaga gacagaagaa acagcaaact gtgactcttc ttcctgctgc 29460 agatttggat gatttctcca aacaattgca acaatccatg agcagtgctg actcaactca 29520 ggcctaaact catgcagacc acacaaggca gatgggctat ataaacgttt tcgcttttcc 29580 gtttacgata tatagtctac tcttgtgcag aatgaattct cgtaactaca tagcacaagt 29640 agatgtagtt aactttaatc tcacatagca atctttaatc agtgtgtaac attagggagg 29700 acttgaaaga gccaccacat tttcaccgag gccacgcgga gtacgatcga gtgtacagtg 29760 aacaatgcta gggagagctg cctatatgga agagccctaa tgtgtaaaat taattttagt 29820 agtgctatcc ccatgnnnnn nnnnnnnnnn nnnnnnnnnn nnnnaaaaaa aaaaaaaaaa 29880 aaaaaaaaaa aaaaaaa 29897 <210> 19 <211> 1272 <212> PRT <213> SARS-CoV2 <220> <221> diferentes_características <222> (240)..(242) <223> Xaa puede ser cualquier aminoácido natural. <400> 19 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ser Gln Cys Val 1 5 10 15 Asn Leu Thr Thr Arg Thr Gln Leu Pro Pro Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Hes Val Ser Gly Thr Asn Gly Thr Lys Arg Phe Ala 65 70 75 80 Asn Pro Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu 85 90 95 Lys Ser Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser 100 105 110 Lys Thr Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile 115 120 125 Lys Val Cys Glu Phe Gln Phe Cys Asn Asp Pro Phe Leu Gly Val Tyr 130 135 140 Tyr Hes Lys Asn Asn Lys Ser Trp Met Glu Ser Glu Phe Arg Val Tyr 145 150 155 160 Ser Ser Ala Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu 165 170 175 Met Asp Leu Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Arg Glu Phe 180 185 190 Val Phe Lys Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr 195 200 205 Pro Ile Asn Leu Val Arg Gly Leu Pro Gln Gly Phe Ser Ala Leu Glu 210 215 220 Pro Leu Val Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Xaa 225 230 235 240 Xaa Xaa Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser Gly 245 250 255 Trp Thr Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro Arg 260 265 270 Thr Phe Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala Val 275 280 285 Asp Cys Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys Ser 290 295 300 Phe Thr Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Val Gln 305 310 315 320 Pro Thr Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys Pro 325 330 335 Phe Gly Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala Trp 340 345 350 Asn Arg Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Val Leu Tyr 355 360 365 Asn Ser Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro Thr 370 375 380 Lys Leu Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe Val 385 390 395 400 Ile Arg Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly Asn 405 410 415 Ile Ala Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys Val 420 425 430 Ile Ala Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn Tyr 435 440 445 Asn Tyr Leu Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe Glu 450 455 460 Arg Asp Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys Asn 465 470 475 480 Gly Val Lys Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly Phe 485 490 495 Gln Pro Thr Tyr Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val Leu 500 505 510 Ser Phe Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys Lys 515 520 525 Ser Thr Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn Gly 530 535 540 Leu Thr Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu Pro 545 550 555 560 Phe Gln Gln Phe Gly Arg Asp Ile Ala Asp Thr Thr Asp Ala Val Arg 565 570 575 Asp Pro Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe Gly 580 585 590 Gly Val Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val Ala 595 600 605 Val Leu Tyr Gln Gly Val Asn Cys Thr Glu Val Pro Val Ala Ile Hes 610 615 620 Ala Asp Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser Asn 625 630 635 640 Val Phe Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Hes Val Asn 645 650 655 Asn Ser Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala Ser 660 665 670 Tyr Gln Thr Gln Thr Asn Ser Pro Arg Arg Ala Arg Ser Val Ala Ser 675 680 685 Gln Ser Ile Ile Ala Tyr Thr Met Ser Leu Gly Val Glu Asn Ser Val 690 695 700 Ala Tyr Ser Asn Asn Ser Ile Ala Ile Pro Thr Asn Phe Thr Ile Ser 705 710 715 720 Val Thr Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val Asp 725 730 735 Cys Thr Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu Leu 740 745 750 Leu Gln Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr Gly 755 760 765 Ile Ala Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln Val 770 775 780 Lys Gln Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe Asn 785 790 795 800 Phe Ser Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser Phe 805 810 815 Ile Glu Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly Phe 820 825 830 Ile Lys Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp Leu 835 840 845 Ile Cys Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu Leu 850 855 860 Thr Asp Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly Thr 865 870 875 880 Ile Thr Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile Pro 885 890 895 Phe Ala Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr Gln 900 905 910 Asn Val Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn Ser 915 920 925 Ala Ile Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala Leu 930 935 940 Gly Lys Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn Thr 945 950 955 960 Leu Val Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val Leu 965 970 975 Asn Asp Ile Leu Ser Arg Leu Asp Lys Val Glu Ala Glu Val Gln Ile 980 985 990 Asp Arg Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val Thr 995 1000 1005 Gln Gln Leu Ile Arg Ala Ala Glu Ile Arg Ala Ser Ala Asn Leu 1010 1015 1020 Ala Ala Thr Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys Arg 1025 1030 1035 Val Asp Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro Gln 1040 1045 1050 Ser Ala Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val Pro 1055 1060 1065 Ala Gln Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes Asp 1070 1075 1080 Gly Lys Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn Gly 1085 1090 1095 Thr Hes Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln Ile 1100 1105 1110 Ile Thr Thr Asp Asn Thr Phe Val Ser Gly Asn Cys Asp Val Val 1115 1120 1125 Ile Gly Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro Glu 1130 1135 1140 Leu Asp Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn Hes 1145 1150 1155 Thr Ser Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn Ala 1160 1165 1170 Ser Val Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu Val 1175 1180 1185 Ala Lys Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu Gly 1190 1195 1200 Lys Tyr Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu Gly 1205 1210 1215 Phe Ile Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met Leu 1220 1225 1230 Cys Cys Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys Ser 1235 1240 1245 Cys Gly Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro Val 1250 1255 1260 Leu Lys Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 20 <211> 29819 <212> ADN <213> SARS-CoV2 <400> 20 caactttcga tctcttgtag atctgttctc taaacgaact ttaaaatctg tgtggctgtc 60 actcggctgc atgcttagtg cactcacgca gtataattaa taactaatta ctgtcgttga 120 caggacacga gtaactcgtc tatcttctgc aggctgctta cggtttcgtc cgtgttgcag 180 ccgatcatca gcacatctag gttttgtccg ggtgtgaccg aaaggtaaga tggagagcct 240 tgtccctggt ttcaacgaga aaacacacgt ccaactcagt ttgcctgttt tacaggttcg 300 cgacgtgctc gtacgtggct ttggagactc cgtggaggag gtcttatcag aggcacgtca 360 acatcttaaa gatggcactt gtggcttagt agaagttgaa aaaggcgttt tgcctcaact 420 tgaacagccc tatgtgttca tcaaacgttc ggatgctcga actgcacctc atggtcatgt 480 tatggttgag ctggtagcag aactcgaagg cattcagtac ggtcgtagtg gtgagacact 540 tggtgtcctt gtccctcatg tgggcgaaat accagtggct taccgcaagg ttcttcttcg 600 taagaacggt aataaaggag ctggtggcca tagttacggc gccgatctaa agtcatttga 660 cttaggcgac gagcttggca ctgatcctta tgaagacttt caagaaaact ggaacactaa 720 acatagcagt ggtgttaccc gtgaactcat gcgtgagctt aacggagggg catacactcg 780 ctatgtcgat aacaacttct gtggccctga tggctaccct cttgagtgca ttaaagacct 840 tctagcacgt gctggtaaag cttcatgcac tttgtccgaa caactggact ttattgacac 900 taagaggggt gtatactgct gccgtgaaca tgagcatgaa attgcttggt acacggaacg 960 ttctgaaaag agctatgaat tgcagacacc ttttgaaatt aaattggcaa agaaatttga 1020 caccttcaat ggggaatgtc caaattttgt atttccctta aattccataa tcaagactat 1080 tcaaccaagg gttgaaaaga aaaagcttga tggctttatg ggtagaattc gatctgtcta 1140 tccagttgcg tcaccaaatg aatgcaacca aatgtgcctt tcaactctca tgaagtgtga 1200 tcattgtggt gaaacttcat ggcagacggg cgattttgtt aaagccactt gcgaattttg 1260 tggcactgag aatttgacta aagaaggtgc cactacttgt ggttacttac cccaaaatgc 1320 tgttgttaaa atttattgtc cagcatgtca caattcagaa gtaggacctg agcatagtct 1380 tgccgaatac cataatgaat ctggcttgaa aaccattctt cgtaagggtg gtcgcactat 1440 tgcctttgga ggctgtgtgt tctcttatgt tggttgccat aacaagtgtg cctattgggt 1500 tccacgtgct agcgctaaca taggttgtaa ccatacaggt gttgttggag aaggttccga 1560 aggtcttaat gacaaccttc ttgaaatact ccaaaaagag aaagtcaaca tcaatattgt 1620 tggtgacttt aaacttaatg aagagatcgc cattattttg gcatcttttt ctgcttccac 1680 aagtgctttt gtggaaactg tgaaaggttt ggattataaa gcattcaaac aaattgttga 1740 atcctgtggt aattttaaag ttacaaaagg aaaagctaaa aaaggtgcct ggaatattgg 1800 tgaacagaaa tcaatactga gtcctcttta tgcatttgca tcagaggctg ctcgtgttgt 1860 acgatcaatt ttctcccgca ctcttgaaac tgctcaaaat tctgtgcgtg ttttacagaa 1920 ggccgctata acaatactag atggaatttc acagtattca ctgagactca ttgatgctat 1980 gatgttcaca tctgatttgg ctactaacaa tctagttgta atggcctaca ttacaggtgg 2040 tgttgttcag ttgacttcgc agtggctaac taacatcttt ggcactgttt atgaaaaact 2100 caaacccgtc cttgattggc ttgaagagaa gtttaaggaa ggtgtagagt ttcttagaga 2160 cggttgggaa attgttaaat ttatctcaac ctgtgcttgt gaaattgtcg gtggacaaat 2220 tgtcacctgt gcaaaggaaa ttaaggagag tgttcagaca ttctttaagc ttgtaaataa 2280 atttttggct ttgtgtgctg actctatcat tattggtgga gctaaactta aagccttgaa 2340 tttaggtgaa acatttgtca cgcactcaaa gggattgtac agaaagtgtg ttaaatccag 2400 agaagaaact ggcctactca tgcctctaaa agccccaaaa gaaattatct tcttagaggg 2460 agaaacactt cccacagaag tgttaacaga ggaagttgtc ttgaaaactg gtgatttaca 2520 accattagaa caacctacta gtgaagctgt tgaagctcca ttggttggta caccagtttg 2580 tattaacggg cttatgttgc tcgaaatcaa agacacagaa aagtactgtg cccttgcacc 2640 taatatgatg gtaacaaaca ataccttcac actcaaaggc ggtgcaccaa caaaggttac 2700 ttttggtgat gatactgtga tagaagtgca aggttacaag agtgtgaata tcacttttga 2760 acttgatgaa aggattgata aagtacttaa tgagaagtgc tctgcctata cagttgaact 2820 cggtacagaa gtaaatgagt tcgcctgtgt tgtggcagat gctgtcataa aaactttgca 2880 accagtatct gaattactta caccactggg cattgattta gatgagtgga gtatggctac 2940 atactactta tttgatgagt ctggtgagtt taaattggct tcacatatgt attgttcttt 3000 ttaccctcca gatgaggatg aagaagaagg tgattgtgaa gaagaagagt ttgagccatc 3060 aactcaatat gagtatggta ctgaagatga ttaccaaggt aaacctttgg aatttggtgc 3120 cacttctgct gctcttcaac ctgaagaaga gcaagaagaa gattggttag atgatgatag 3180 tcaacaaact gttggtcaac aagacggcag tgaggacaat cagacaacta ctattcaaac 3240 aattgttgag gttcaacctc aattagagat ggaacttaca ccagttgttc agactattga 3300 agtgaatagt tttagtggtt atttaaaact tactgacaat gtatacatta aaaatgcaga 3360 cattgtggaa gaagctaaaa aggtaaaacc aacagtggtt gttaatgcag ccaatgttta 3420 ccttaaacat ggaggaggtg ttgcaggagc cttaaataag gctactaaca atgccatgca 3480 agttgaatct gatgattaca tagctactaa tggaccactt aaagtgggtg gtagttgtgt 3540 tttaagcgga cacaatcttg ctaaacactg tcttcatgtt gtcggcccaa atgttaacaa 3600 aggtgaagac attcaacttc ttaagagtgc ttatgaaaat tttaatcagc acgaagttct 3660 acttgcacca ttattatcag ctggtatttt tggtgctgac cctatacatt ctttaagagt 3720 ttgtgtagat actgttcgca caaatgtcta cttagctgtc tttgataaaa atctctatga 3780 caaacttgtt ttaagctttt tggaaatgaa gagtgaaaag caagttgaac aaaagatcgc 3840 tgagattcct aaagaggaag ttaagccatt tataactgaa agtaaacctt cagttgaaca 3900 gagaaaacaa gatgataaga aaatcaaagc ttgtgttgaa gaagttacaa caactctgga 3960 agaaactaag ttcctcacag aaaacttgtt actttatatt gacattaatg gcaatcttca 4020 tccagattct gccactcttg ttagtgacat tgacatcact ttcttaaaga aagatgctcc 4080 atatatagtg ggtgatgttg ttcaagaggg tgttttaact gctgtggtta tacctactaa 4140 aaaggctggt ggcactactg aaatgctagc gaaagctttg agaaaagtgc caacagacaa 4200 ttatataacc acttacccgg gtcagggttt aaatggttac actgtagagg aggcaaagac 4260 agtgcttaaa aagtgtaaaa gtgcctttta cattctacca tctattatct ctaatgagaa 4320 gcaagaaatt cttggaactg tttcttggaa tttgcgagaa atgcttgcac atgcagaaga 4380 aacacgcaaa ttaatgcctg tctgtgtgga aactaaagcc atagtttcaa ctatacagcg 4440 taaatataag ggtattaaaa tacaagaggg tgtggttgat tatggtgcta gattttactt 4500 ttacaccagt aaaacaactg tagcgtcact tatcaacaca cttaacgatc taaatgaaac 4560 tcttgttaca atgccacttg gctatgtaac acatggctta aatttggaag aagctgctcg 4620 gtatatgaga tctctcaaag tgccagctac agtttctgtt tcttcacctg atgctgttac 4680 agcgtataat ggttatctta cttcttcttc taaaacacct gaagaacatt ttattgaaac 4740 catctcactt gctggttcct ataaagattg gtcctattct ggacaatcta cacaactagg 4800 tatagaattt cttaagagag gtgataaaag tgtatattac actagtaatc ctaccacatt 4860 ccacctagat ggtgaagtta tcacctttga caatcttaag acacttcttt ctttgagaga 4920 agtgaggact attaaggtgt ttacaacagt agacaacatt aacctccaca cgcaagttgt 4980 ggacatgtca atgacatatg gacaacagtt tggtccaact tatttggatg gagctgatgt 5040 tactaaaata aaacctcata attcacatga aggtaaaaca ttttatgttt tacctaatga 5100 tgacactcta cgtgttgagg cttttgagta ctaccacaca actgatccta gttttctggg 5160 taggtacatg tcagcattaa atcacactaa aaagtggaaa tacccacaag ttaatggttt 5220 aacttctatt aaatgggcag ataacaactg ttatcttgcc actgcattgt taacactcca 5280 acaaatagag ttgaagttta atccacctgc tctacaagat gcttattaca gagcaagggc 5340 tggtgaagct gctaactttt gtgcacttat cttagcctac tgtaataaga cagtaggtga 5400 gttaggtgat gttagagaaa caatgagtta cttgtttcaa catgccaatt tagattcttg 5460 caaaagagtc ttgaacgtgg tgtgtaaaac ttgtggacaa cagcagacaa cccttaaggg 5520 tgtagaagct gttatgtaca tgggcacact ttcttatgaa caatttaaga aaggtgttca 5580 gataccttgt acgtgtggta aacaagctac acaatatcta gtacaacagg agtcaccttt 5640 tgttatgatg tcagcaccac ctgctcagta tgaacttaag catggtacat ttacttgtgc 5700 tagtgagtac actggtaatt accagtgtgg tcactataaa catataactt ctaaagaaac 5760 tttgtattgc atagacggtg ctttacttac aaagtcctca gaatacaaag gtcctattac 5820 ggatgttttc tacaaagaaa acagttacac aacaaccata aaaccagtta cttataaatt 5880 ggatggtgtt gtttgtacag aaattgaccc taagttggac aattattata agaaagacaa 5940 ttcttatttc acagagcaac caattgatct tgtaccaaac caaccatatc caaacgcaag 6000 cttcgataat tttaagtttg tatgtgataa tatcaaattt gctgatgatt taaaccagtt 6060 aactggttat aagaaacctg cttcaagaga gcttaaagtt acatttttcc ctgacttaaa 6120 tggtgatgtg gtggctattg attataaaca ctacacaccc tcttttaaga aaggagctaa 6180 attgttacat aaacctattg tttggcatgt taacaatgca actaataaag ccacgtataa 6240 accaaatacc tggtgtatac gttgtctttg gagcacaaaa ccggttgaaa catcaaattc 6300 gtttgatgta ctgaagtcag aggacgcgca gggaatggat aatcttgcct gcgaagatct 6360 aaaaccagtc tctgaagaag tagtggaaaa tcctaccata cagaaagacg ttcttgagtg 6420 taatgtgaaa actaccgaag ttgtaggaga cattatactt aaaccagcaa ataatagttt 6480 aaaaattaca gaagaggttg gccacacaga tctaatggct gcttatgtag acaattctag 6540 tcttactatt aagaaaccta atgaattatc tagagtgtta ggtttgaaaa cccttgctac 6600 tcatggttta gctgctgtta atagtgtccc ttgggatact atagctaatt atgctaagcc 6660 ttttcttaac aaagttgtta gtacaactac taacatagtt acacggtgtt taaaccgtgt 6720 ttgtactaat tatatgcctt atttctttac tttattgcta caattgtgta cttttactag 6780 aagtacaaat tctagaatta aagcatctat gccgactact atagcaaaga atactgttaa 6840 gagtgtcggt aaattttgtc tagaggcttc atttaattat ttgaagtcac ctaatttttc 6900 taaactgata aatattataa tttggttttt actattaagt gtttgcctag gttctttaat 6960 ctactcaacc gctgctttag gtgttttaat gtctaattta ggcatgcctt cttactgtac 7020 tggttacaga gaaggctatt tgaactctac taatgtcact attgcaacct actgtactgg 7080 ttctatacct tgtagtgttt gtcttagtgg tttagattct ttagacacct atccttcttt 7140 agaaactata caaattacca tttcatcttt taaatgggat ttaactgctt ttggcttagt 7200 tgcagagtgg tttttggcat atattctttt cactaggttt ttctatgtac ttggattggc 7260 tgcaatcatg caattgtttt tcagctattt tgcagtacat tttattagta attcttggct 7320 tatgtggtta ataattaatc ttgtacaaat ggccccgatt tcagctatgg ttagaatgta 7380 catcttcttt gcatcatttt attatgtatg gaaaagttat gtgcatgttg tagacggttg 7440 taattcatca acttgtatga tgtgttacaa acgtaataga gcaacaagag tcgaatgtac 7500 aactattgtt aatggtgtta gaaggtcctt ttatgtctat gctaatggag gtaaaggctt 7560 ttgcaaacta cacaattgga attgtgttaa ttgtgataca ttctgtgctg gtagtacatt 7620 tattagtgat gaagttgcga gagacttgtc actacagttt aaaagaccaa taaatcctac 7680 tgaccagtct tcttacatcg ttgatagtgt tacagtgaag aatggttcca tccatcttta 7740 ctttgataaa gctggtcaaa agacttatga aagacattct ctctctcatt ttgttaactt 7800 agacaacctg agagctaata acactaaagg ttcattgcct attaatgtta tagtttttga 7860 tggtaaatca aaatgtgaag aatcatctgc aaaatcagcg tctgtttact acagtcagct 7920 tatgtgtcaa cctatactgt tactagatca ggcattagtg tctgatgttg gtgatagtgc 7980 ggaagttgca gttaaaatgt ttgatgctta cgttaatacg ttttcatcaa cttttaacgt 8040 accaatggaa aaactcaaaa cactagttgc aactgcagaa gctgaacttg caaagaatgt 8100 gtccttagac aatgtcttat ctacttttat ttcagcagct cggcaagggt ttgttgattc 8160 agatgtagaa actaaagatg ttgttgaatg tcttaaattg tcacatcaat ctgacataga 8220 agttactggc gatagttgta ataactatat gctcacctat aacaaagttg aaaacatgac 8280 accccgtgac cttggtgctt gtattgactg tagtgcgcgt catattaatg cgcaggtagc 8340 aaaaagtcac aacattgctt tgatatggaa cgttaaagat ttcatgtcat tgtctgaaca 8400 actacgaaaa caaatacgta gtgctgctaa aaagaataac ttacctttta agttgacatg 8460 tgcaactact agacaagttg ttaatgttgt aacaacaaag atagcactta agggtggtaa 8520 aattgttaat aattggttga agcagttaat taaagttaca cttgtgttcc tttttgttgc 8580 tgctattttc tatttaataa cacctgttca tgtcatgtct aaacatactg acttttcaag 8640 tgaaatcata ggatacaagg ctattgatgg tggtgtcact cgtgacatag catctacaga 8700 tacttgtttt gctaacaaac atgctgattt tgacacatgg tttagccagc gtggtggtag 8760 ttatactaat gacaaagctt gcccattgat tgctgcagtc ataacaagag aagtgggttt 8820 tgtcgtgcct ggtttgcctg gcacgatatt acgcacaact aatggtgact ttttgcattt 8880 cttacctaga gtttttagtg cagttggtaa catctgttac acaccatcaa aacttataga 8940 gtacactgac tttgcaacat cagcttgtgt tttggctgct gaatgtacaa tttttaaaga 9000 tgcttctggt aagccagtac catattgtta tgataccaat gtactagaag gttctgttgc 9060 ttatgaaaat ttacgccctg acacacgtta tgtgctcatg gatggctcta ttattcaatt 9120 tcctaacacc taccttgaag gttctgttag agtggtaaca acttttgatt ctgagtactg 9180 taggcacggc acttgtgaaa gatcagaagc tggtgtttgt gtatctacta gtggtagatg 9240 ggtacttaac aatgattatt acagatcttt accaggagtt ttctgtggtg tagatgctgt 9300 aaatttactt actaatatgt ttacaccact aattcaacct attggtgctt tggacatatc 9360 agcatctata gtagctggtg gtattgtagc tatcgtagta acatgccttg cctactattt 9420 tatgaggttt agaagagctt ttggtgaata cagtcatgta gttgccttta atactttact 9480 attccttatg tcattcactg tactctgttt aacaccagtt tactcattct tacctggtgt 9540 ttattctgtt atttacttgt acttgacatt ttatcttact aatgatgttt cttttttagc 9600 acatattcag tggatggtta tgttcacacc tttagtacct ttctggataa caattgctta 9660 tatcatttgt atttccacaa agcatttcta ttggttcttt agtaattacc taaagagacg 9720 tgtagtcttt aatggtgttt cctttagtac ttttgaagaa gctgcgctgt gcaccttttt 9780 gttaaataaa gaaatgtatc taaagttgcg tagtgatgtg ctattacctc ttacgcaata 9840 taatagatac ttagctcttt ataataagta caagtatttt agtggagcaa tggatacaac 9900 tagctacaga gaagctgctt gttgtcatct cgcaaaggct ctcaatgact tcagtaactc 9960 aggttctgat gttctttacc aaccaccaca aacctctatc acctcagctg ttttgcagag 10020 tggttttaga aaaatggcat tcccatctgg taaagttgag ggttgtatgg tacaagtaac 10080 ttgtggtaca actacactta acggtctttg gcttgatgac gtagtttact gtccaagaca 10140 tgtgatctgc acctctgaag acatgcttaa ccctaattat gaagatttac tcattcgtaa 10200 gtctaatcat aatttcttgg tacaggctgg taatgttcaa ctcagggtta ttggacattc 10260 tatgcaaaat tgtgtactta agcttaaggt tgatacagcc aatcctaaga cacctaagta 10320 taagtttgtt cgcattcaac caggacagac tttttcagtg ttagcttgtt acaatggttc 10380 accatctggt gtttaccaat gtgctatgag gcccaatttc actattaagg gttcattcct 10440 taatggttca tgtggtagtg ttggttttaa catagattat gactgtgtct ctttttgtta 10500 catgcaccat atggaattac caactggagt tcatgctggc acagacttag aaggtaactt 10560 ttatggacct tttgttgaca ggcaaacagc acaagcagct ggtacggaca caactattac 10620 agttaatgtt ttagcttggt tgtacgctgc tgttataaat ggagacaggt ggtttctcaa 10680 tcgatttacc acaactctta atgactttaa ccttgtggct atgaagtaca attatgaacc 10740 tctaacacaa gaccatgttg acatactagg acctctttct gctcaaactg gaattgtcgt 10800 tttagatatg tgtgcttcat taaaagaatt actgcaaaat ggtatgaatg gacgtaccat 10860 attgggtagt gctttattag aagatgaatt tacacctttt gatgttgtta gacaatgctc 10920 aggtgttact ttccaaagtg cagtgaaaag aacaatcaag ggtacacacc actggttgtt 10980 actcacaatt ttgacttcac ttttagtttt agtccagagt actcaatggt ctttgttctt 11040 ttttttgtat gaaaatgcct ttttaccttt tgctatgggt attattgcta tgtctgcttt 11100 tgcaatgatg tttgtcaaac ataagcatgc atttctctgt ttgtttttgt taccttctct 11160 tgccactgta gcttatttta atatggtcta tatgcctgct agttgggtga tgcgtattat 11220 gacatggttg gatatggttg atactagttt gaagctaaaa gactgtgtta tgtatgcatc 11280 agctgtagtg ttactaatcc ttatgacagc aagaactgtg tatgatgatg gtgctaggag 11340 agtgtggaca cttatgaatg tcttgacact cgtttataaa gtttattatg gtaatgcttt 11400 agatcaagcc atttccatgt gggctcttat aatctctgtt acttctaact actcaggtgt 11460 agttacaact gtcatgtttt tggccagagg tattgttttt atgtgtgttg agtattgccc 11520 tattttcttc ataactggta atacacttca gtgtataatg ctagtttatt gtttcttagg 11580 ctatttttgt acttgttact ttggcctctt ttgtttactc aaccgctact ttagactgac 11640 tcttggtgtt tatgattact tagtttctac acaggagttt agatatatga attcacaggg 11700 actactccca cccaagaata gcatagatgc cttcaaactc aacattaaat tgttgggtgt 11760 tggtggcaaa ccttgtatca aagtagccac tgtacagtct aaaatgtcag atgtaaagtg 11820 cacatcagta gtcttactct cagttttgca acaactcaga gtagaatcat catctaaatt 11880 gtgggctcaa tgtgtccagt tacacaatga cattctctta gctaaagata ctactgaagc 11940 ctttgaaaaa atggtttcac tactttctgt tttgctttcc atgcagggtg ctgtagacat 12000 aaacaagctt tgtgaagaaa tgctggacaa cagggcaacc ttacaagcta tagcctcaga 12060 gtttagttcc cttccatcat atgcagcttt tgctactgct caagaagctt atgagcaggc 12120 tgttgctaat ggtgattctg aagttgttct taaaaagttg aagaagtctt tgaatgtggc 12180 taaatctgaa tttgaccgtg atgcagccat gcaacgtaag ttggaaaaga tggctgatca 12240 agctatgacc caaatgtata aacaggctag atctgaggac aagagggcaa aagttactag 12300 tgctatgcag acaatgcttt tcactatgct tagaaagttg gataatgatg cactcaacaa 12360 cattatcaac aatgcaagag atggttgtgt tcccttgaac ataatacctc ttacaacagc 12420 agccaaacta atggttgtca taccagacta taacacatat aaaaatacgt gtgatggtac 12480 aacatttact tatgcatcag cattgtggga aatccaacag gttgtagatg cagatagtaa 12540 aattgttcaa cttagtgaaa ttagtatgga caattcacct aatttagcat ggcctcttat 12600 tgtaacagct ttaagggcca attctgctgt caaattacag aataatgagc ttagtcctgt 12660 tgcactacga cagatgtctt gtgctgccgg tactacacaa actgcttgca ctgatgacaa 12720 tgcgttagct tattacaaca caacaaaggg aggtaggttt gtacttgcac tgttatccga 12780 tttacaggat ttgaaatggg ctagattccc taagagtgat ggaactggta ctatctatac 12840 agaactggaa ccaccttgta ggtttgttac agacacacct aaaggtccta aagtgaagta 12900 tttatacttt attaaaggat taaacaacct aaatagaggt atggtacttg gtagtttagc 12960 tgccacagta cgtctacaag ctggtaatgc aacagaagtg cctgccaatt caactgtatt 13020 atctttctgt gcttttgctg tagatgctgc taaagcttac aaagattatc tagctagtgg 13080 gggacaacca atcactaatt gtgttaagat gttgtgtaca cacactggta ctggtcaggc 13140 aataacagtt acaccggaag ccaatatgga tcaagaatcc tttggtggtg catcgtgttg 13200 tctgtactgc cgttgccaca tagatcatcc aaatcctaaa ggattttgtg acttaaaagg 13260 taagtatgta caaataccta caacttgtgc taatgaccct gtgggtttta cacttaaaaa 13320 cacagtctgt accgtctgcg gtatgtggaa aggttatggc tgtagttgtg atcaactccg 13380 cgaacccatg cttcagtcag ctgatgcaca atcgttttta aacgggtttg cggtgtaagt 13440 gcagcccgtc ttacaccgtg cggcacaggc actagtactg atgtcgtata cagggctttt 13500 gacatctaca atgataaagt agctggtttt gctaaattcc taaaaactaa ttgttgtcgc 13560 ttccaagaaa aggacgaaga tgacaattta attgattctt actttgtagt taagagacac 13620 actttctcta actaccaaca tgaagaaaca atttataatt tacttaagga ttgtccagct 13680 gttgctaaac atgacttctt taagtttaga atagacggtg acatggtacc acatatatca 13740 cgtcaacgtc ttactaaata cacaatggca gacctcgtct atgctttaag gcattttgat 13800 gaaggtaatt gtgatacatt aaaagaaata cttgtcacat acaattgttg tgatgatgat 13860 tatttcaata aaaaggactg gtatgatttt gtagaaaacc cagatatatt acgcgtatac 13920 gccaacttag gtgaacgtgt acgccaagct ttgttaaaaa cagtacaatt ctgtgatgcc 13980 atgcgaaatg ctggtattgt tggtgtactg acattagata atcaagatct caatggtaac 14040 tggtatgatt tcggtgattt catacaaacc acgccaggta gtggagttcc tgttgtagat 14100 tcttattatt cattgttaat gcctatatta accttgacca gggctttaac tgcagagtca 14160 catgttgaca ctgacttaac aaagccttac attaagtggg atttgttaaa atatgacttc 14220 acggaagaga ggttaaaact ctttgaccgt tattttaaat attgggatca gacataccac 14280 ccaaattgtg ttaactgttt ggatgacaga tgcattctgc attgtgcaaa ctttaatgtt 14340 ttattctcta cagtgttccc acttacaagt tttggaccac tagtgagaaa aatatttgtt 14400 gatggtgttc catttgtagt ttcaactgga taccacttca gagagctagg tgttgtacat 14460 aatcaggatg taaacttaca tagctctaga cttagtttta aggaattact tgtgtatgct 14520 gctgaccctg ctatgcacgc tgcttctggt aatctattac tagataaacg cactacgtgc 14580 ttttcagtag ctgcacttac taacaatgtt gcttttcaaa ctgtcaaacc cggtaatttt 14640 aacaaagact tctatgactt tgctgtgtct aagggtttct ttaaggaagg aagttctgtt 14700 gaattaaaac acttcttctt tgctcaggat ggtaatgctg ctatcagcga ttatgactac 14760 tatcgttata atctaccaac aatgtgtgat atcagacaac tactatttgt agttgaagtt 14820 gttgataagt actttgattg ttacgatggt ggctgtatta atgctaacca agtcatcgtc 14880 aacaacctag acaaatcagc tggttttcca tttaataaat ggggtaaggc tagactttat 14940 tatgattcaa tgagttatga ggatcaagat gcacttttcg catatacaaa acgtaatgtc 15000 atccctacta taactcaaat gaatcttaag tatgccatta gtgcaaagaa tagagctcgc 15060 accgtagctg gtgtctctat ctgtagtact atgaccaata gacagtttca tcaaaaatta 15120 ttgaaatcaa tagccgccac tagaggagct actgtagtaa ttggaacaag caaattctat 15180 ggtggttggc acaacatgtt aaaaactgtt tatagtgatg tagaaaaccc tcaccttatg 15240 ggttgggatt atcctaaatg tgatagagcc atgcctaaca tgcttagaat tatggcctca 15300 cttgttcttg ctcgcaaaca tacaacgtgt tgtagcttgt cacaccgttt ctatagatta 15360 gctaatgagt gtgctcaagt attgagtgaa atggtcatgt gtggcggttc actatatgtt 15420 aaaccaggtg gaacctcatc aggagatgcc acaactgctt atgctaatag tgtttttaac 15480 atttgtcaag ctgtcacggc caatgttaat gcacttttat ctactgatgg taacaaaatt 15540 gccgataagt atgtccgcaa tttacaacac agactttatg agtgtctcta tagaaataga 15600 gatgttgaca cagactttgt gaatgagttt tacgcatatt tgcgtaaaca tttctcaatg 15660 atgatactct ctgacgatgc tgttgtgtgt ttcaatagca cttatgcatc tcaaggtcta 15720 gtggctagca taaagaactt taagtcagtt ctttattatc aaaacaatgt ttttatgtct 15780 gaagcaaaat gttggactga gactgacctt actaaaggac ctcatgaatt ttgctctcaa 15840 catacaatgc tagttaaaca gggtgatgat tatgtgtacc ttccttaccc agatccatca 15900 agaatcctag gggccggctg ttttgtagat gatatcgtaa aaacagatgg tacacttatg 15960 attgaacggt tcgtgtcttt agctatagat gcttacccac ttactaaaca tcctaatcag 16020 gagtatgctg atgtctttca tttgtactta caatacataa gaaagctaca tgatgagtta 16080 acaggacaca tgttagacat gtattctgtt atgcttacta atgataacac ttcaaggtat 16140 tgggaacctg agttttatga ggctatgtac acaccgcata cagtcttaca ggctgttggg 16200 gcttgtgttc tttgcaattc acagacttca ttaagatgtg gtgcttgcat acgtagacca 16260 ttcttatgtt gtaaatgctg ttacgaccat gtcatatcaa catcacataa attagtcttg 16320 tctgttaatc cgtatgtttg caatgctcca ggttgtgatg tcacagatgt gactcaactt 16380 tacttaggag gtatgagcta ttattgtaaa tcacataaac cacccattag ttttccattg 16440 tgtgctaatg gacaagtttt tggtttatat aaaaatacat gtgttggtag cgataatgtt 16500 actgacttta atgcaattgc aacatgtgac tggacaaatg ctggtgatta cattttagct 16560 aacacctgta ctgaaagact caagcttttt gcagcagaaa cgctcaaagc tactgaggag 16620 acatttaaac tgtcttatgg tattgctact gtacgtgaag tgctgtctga cagagaatta 16680 catctttcat gggaagttgg taaacctaga ccaccactta accgaaatta tgtctttact 16740 ggttatcgtg taactaaaaa cagtaaagta caaataggag agtacacctt tgaaaaaggt 16800 gactatggtg atgctgttgt ttaccgaggt acaacaactt acaaattaaa tgttggtgat 16860 tattttgtgc tgacatcaca tacagtaatg ccattaagtg cacctacact agtgccacaa 16920 gagcactatg ttagaattac tggcttatac ccaacactca atatctcaga tgagttttct 16980 agcaatgttg caaattatca aaaggttggt atgcaaaagt attctacact ccagggacca 17040 cctggtactg gtaagagtca ttttgctatt ggcctagctc tctactaccc ttctgctcgc 17100 atagtgtata cagcttgctc tcatgccgct gttgatgcac tatgtgagaa ggcattaaaa 17160 tatttgccta tagataaatg tagtagaatt atacctgcac gtgctcgtgt agattgtttt 17220 gataaattca aagtgaattc aacattagaa cagtatgtct tttgtactgt aaatgcattg 17280 cctgagacga cagcagatat agttgtcttt gatgaaattt caatggccac aaattatgat 17340 ttgagtgttg tcaatgccag attacgtgct aagcactatg tgtacattgg cgaccctgct 17400 caattacctg caccacgcac attgctaact aagggcacac tagaaccaga atatttcaat 17460 tcagtgtgta gacttatgaa aactataggt ccagacatgt tcctcggaac ttgtcggcgt 17520 tgtcctgctg aaattgttga cactgtgagt gctttggttt atgataataa gcttaaagca 17580 cataaagaca aatcagctca atgctttaaa atgttttata agggtgttat cacgcatgat 17640 gtttcatctg caattaacag gccacaaata ggcgtggtaa gagaattcct tacacgtaac 17700 cctgcttgga gaaaagctgt ctttatttca ccttataatt cacagaatgc tgtagcctca 17760 aagattttgg gactaccaac tcaaactgtt gattcatcac agggctcaga atatgactat 17820 gtcatattca ctcaaaccac tgaaacagct cactcttgta atgtaaacag atttaatgtt 17880 gctattacca gagcaaaagt aggcatactt tgcataatgt ctgatagaga cctttatgac 17940 aagttgcaat ttacaagtct tgaaattcca cgtaggaatg tggcaacttt acaagctgaa 18000 aatgtaacag gactctttaa agattgtagt aaggtaatca ctgggttaca tcctacacag 18060 gcacctacac acctcagtgt tgacactaaa ttcaaaactg aaggtttatg tgttgacata 18120 cctggcatac ctaaggacat gacctataga agactcatct ctatgatggg ttttaaaatg 18180 aattatcaag ttaatggtta ccctaacatg tttatcaccc gcgaagaagc tataagacat 18240 gtacgtgcat ggattggctt cgatgtcgag gggtgtcatg ctactagaga agctgttggt 18300 accaatttac ctttacagct aggtttttct acaggtgtta acctagttgc tgtacctaca 18360 ggttatgttg atacacctaa taatacagat ttttccagag ttagtgctaa accaccgcct 18420 ggagatcaat ttaaacacct cataccactt atgtacaaag gacttccttg gaatgtagtg 18480 cgtataaaga ttgtacaaat gttaagtgac acacttaaaa atctctctga cagagtcgta 18540 tttgtcttat gggcacatgg ctttgagttg acatctatga agtattttgt gaaaatagga 18600 cctgagcgca cctgttgtct atgtgataga cgtgccacat gcttttccac tgcttcagac 18660 acttatgcct gttggcatca ttctattgga tttgattacg tctataatcc gtttatgatt 18720 gatgttcaac aatggggttt tacaggtaac ctacaaagca accatgatct gtattgtcaa 18780 gtccatggta atgcacatgt agctagttgt gatgcaatca tgactaggtg tctagctgtc 18840 cacgagtgct ttgttaagcg tgttgactgg actattgaat atcctataat tggtgatgaa 18900 ctgaagatta atgcggcttg tagaaaggtt caacacatgg ttgttaaagc tgcattatta 18960 gcagacaaat tcccagttct tcacgacatt ggtaacccta aagctattaa gtgtgtacct 19020 caagctgatg tagaatggaa gttctatgat gcacagcctt gtagtgacaa agcttataaa 19080 atagaagaat tattctattc ttatgccaca cattctgaca aattcacaga tggtgtatgc 19140 ctattttgga attgcaatgt cgatagatat cctgctaatt ccattgtttg tagatttgac 19200 actagagtgc tatctaacct taacttgcct ggttgtgatg gtggcagttt gtatgtaaat 19260 aaacatgcat tccacacacc agcttttgat aaaagtgctt ttgttaattt aaaacaatta 19320 ccatttttct attactctga cagtccatgt gagtctcatg gaaaacaagt agtgtcagat 19380 atagattatg taccactaaa gtctgctacg tgtataacac gttgcaattt aggtggtgct 19440 gtctgtagac atcatgctaa tgagtacaga ttgtatctcg atgcttataa catgatgatc 19500 tcagctggct ttagcttgtg ggtttacaaa caatttgata cttataacct ctggaacact 19560 tttacaagac ttcagagttt agaaaatgtg gcttttaatg ttgtaaataa gggacacttt 19620 gatggacaac agggtgaagt accagtttct atcattaata acactgttta cacaaaagtt 19680 gatggtgttg atgtagaatt gtttgaaaat aaaacaacat tacctgttaa tgtagcattt 19740 gagctttggg ctaagcgcaa cattaaacca gtaccagagg tgaaaatact caataatttg 19800 ggtgtggaca ttgctgctaa tactgtgatc tgggactaca aaagagatgc tccagcacat 19860 atatctacta ttggtgtttg ttctatgact gacatagcca agaaaccaac tgaaacgatt 19920 tgtgcaccac tcactgtctt ttttgatggt agagttgatg gtcaagtaga cttatttaga 19980 aatgcccgta atggtgttct tattacagaa ggtagtgtta aaggtttaca accatctgta 20040 ggtcccaaac aagctagtct taatggagtc acattaattg gagaagccgt aaaaacacag 20100 ttcaattatt ataagaaagt tgatggtgtt gtccaacaat tacctgaaac ttactttact 20160 cagagtagaa atttacaaga atttaaaccc aggagtcaaa tggaaattga tttcttagaa 20220 ttagctatgg atgaattcat tgaacggtat aaattagaag gctatgcctt cgaacatatc 20280 gtttatggag attttagtca tagtcagtta ggtggtttac atctactgat tggactagct 20340 aaacgtttta aggaatcacc ttttgaatta gaagatttta ttcctatgga cagtacagtt 20400 aaaaactatt tcataacaga tgcgcaaaca ggttcatcta agtgtgtgtg ttctgttatt 20460 gatttattac ttgatgattt tgttgaaata ataaaatccc aagatttatc tgtagtttct 20520 aaggttgtca aagtgactat tgactataca gaaatttcat ttatgctttg gtgtaaagat 20580 ggccatgtag aaacatttta cccaaaatta caatctagtc aagcgtggca accgggtgtt 20640 gctatgccta atctttacaa aatgcaaaga atgctattag aaaagtgtga ccttcaaaat 20700 tatggtgata gtgcaacatt acctaaaggc ataatgatga atgtcgcaaa atatactcaa 20760 ctgtgtcaat atttaaacac attaacatta gctgtaccct ataatatgag agttatacat 20820 tttggtgctg gttctgataa aggagttgca ccaggtacag ctgttttaag acagtggttg 20880 cctacgggta cgctgcttgt cgattcagat cttaatgact ttgtctctga tgcagattca 20940 actttgattg gtgattgtgc aactgtacat acagctaata aatgggatct cattattagt 21000 gatatgtacg accctaagac taaaaatgtt acaaaagaaa atgactctaa agagggtttt 21060 ttcacttaca tttgtgggtt tatacaacaa aagctagctc ttggaggttc cgtggctata 21120 aagataacag aacattcttg gaatgctgat ctttataagc tcatgggaca cttcgcatgg 21180 tggacagcct ttgttactaa tgtgaatgcg tcatcatctg aagcattttt aattggatgt 21240 aattatcttg gcaaaccacg cgaacaaata gatggttatg tcatgcatgc aaattacata 21300 ttttggagga atacaaatcc aattcagttg tcttcctatt ctttatttga catgagtaaa 21360 tttcccctta aattaagggg tactgctgtt atgtctttaa aagaaggtca aatcaatgat 21420 atgattttat ctcttcttag taaaggtaga cttataatta gagaaaacaa cagagttgtt 21480 atttctagtg atgttcttgt taacaactaa acgaacaatg tttgtttttc ttgttttatt 21540 gccactagtc tctagtcagt gtgttaattt tacaaacaga actcaattac cctctgcata 21600 cactaattct ttcacacgtg gtgtttatta ccctgacaaa gttttcagat cctcagtttt 21660 acattcaact caggacttgt tcttaccttt cttttccaat gttacttggt tccatgctat 21720 acatgtctct gggaccaatg gtactaagag gtttgataac cctgtcctac catttaatga 21780 tggtgtttat tttgcttcca ctgagaagtc taacataata agaggctgga tttttggtac 21840 tactttagat tcgaagaccc agtccctact tattgttaat aacgctacta atgttgttat 21900 taaagtctgt gaatttcaat tttgtaatta tccatttttg ggtgtttatt accacaaaaa 21960 caacaaaagt tggatggaaa gtgagttcag agtttattct agtgcgaata attgcacttt 22020 tgaatatgtc tctcagcctt ttcttatgga ccttgaagga aaacagggta atttcaaaaa 22080 tcttagtgaa tttgtgttta agaatattga tggttatttt aaaatatatt ctaagcacac 22140 gcctattaat ttagtgcgtg atctccctca gggtttttcg gctttagaac cattggtaga 22200 tttgccaata ggtattaaca tcactaggtt tcaaacttta cttgctttac atagaagtta 22260 tttgactcct ggtgattctt cttcaggttg gacagctggt gctgcagctt attatgtggg 22320 ttatcttcaa cctaggactt ttctattaaa atataatgaa aatggaacca ttacagatgc 22380 tgtagactgt gcacttgacc ctctctcaga aacaaagtgt acgttgaaat ccttcactgt 22440 agaaaaagga atctatcaaa cttctaactt tagagtccaa ccaacagaat ctattgttag 22500 atttcctaat attacaaact tgtgcccttt tggtgaagtt tttaacgcca ccagatttgc 22560 atctgtttat gcttggaaca ggaagagaat cagcaactgt gttgctgatt attctgtcct 22620 atataattcc gcatcatttt ccacttttaa gtgttatgga gtgtctccta ctaaattaaa 22680 tgatctctgc tttactaatg tctatgcaga ttcatttgta attagaggtg atgaagtcag 22740 acaaatcgct ccagggcaaa ctggaacgat tgctgattat aattataaat taccagatga 22800 ttttacaggc tgcgttatag cttggaattc taacaatctt gattctaagg ttggtggtaa 22860 ttataattac ctgtatagat tgtttaggaa gtctaatctc aaaccttttg agagagatat 22920 ttcaactgaa atctatcagg ccggtagcac accttgtaat ggtgttaaag gttttaattg 22980 ttactttcct ttacaatcat atggtttcca acccacttat ggtgttggtt accaaccata 23040 cagagtagta gtactttctt ttgaacttct acatgcacca gcaactgttt gtggacctaa 23100 aaagtctact aatttggtta aaaacaaatg tgtcaatttc aacttcaatg gtttaacagg 23160 cacaggtgtt cttactgagt ctaacaaaaa gtttctgcct ttccaacaat ttggcagaga 23220 cattgctgac actactgatg ctgtccgtga tccacagaca cttgagattc ttgacattac 23280 accatgttct tttggtggtg tcagtgttat aacaccagga acaaatactt ctaatcaggt 23340 tgctgttctt tatcagggtg ttaactgcac agaagtccct gttgctattc atgcagatca 23400 acttactcct acttggcgtg tttattctac aggttctaat gtttttcaaa cacgtgcagg 23460 ctgtttaata ggggctgaat atgtcaacaa ctcatatgag tgtgacatac ccattggtgc 23520 aggtatatgc gctagttatc agactcagac taattctcct cggcgggcac gtagtgtagc 23580 tagtcaatcc atcattgcct acactatgtc acttggtgca gaaaattcag ttgcttactc 23640 taataactct attgccatac ccacaaattt tactattagt gttaccacag aaattctacc 23700 agtgtctatg accaagacat cagtagattg tacaatgtac atttgtggtg attcaactga 23760 atgcagcaat cttttgttgc aatatggcag tttttgtaca caattaaacc gtgctttaac 23820 tggaatagct gttgaacaag acaaaaacac ccaagaagtt tttgcacaag tcaaacaaat 23880 ttacaaaaca ccaccaatta aagattttgg tggttttaat ttttcacaaa tattaccaga 23940 tccatcaaaa ccaagcaaga ggtcatttat tgaagatcta cttttcaaca aagtgacact 24000 tgcagatgct ggcttcatca aacaatatgg tgattgcctt ggtgatattg ctgctagaga 24060 cctcatttgt gcacaaaagt ttaacggcct tactgttttg ccacctttgc tcacagatga 24120 aatgattgct caatacactt ctgcactgtt agcgggtaca atcacttctg gttggacctt 24180 tggtgcaggt gctgcattac aaataccatt tgctatgcaa atggcttata ggtttaatgg 24240 tattggagtt acacagaatg ttctctatga gaaccaaaaa ttgattgcca accaatttaa 24300 tagtgctatt ggcaaaattc aagactcact ttcttccaca gcaagtgcac ttggaaaact 24360 tcaagatgtg gtcaaccaaa atgcacaagc tttaaacacg cttgttaaac aacttagctc 24420 caattttggt gcaatttcaa gtgttttaaa tgatatcctt tcacgtcttg acaaagttga 24480 ggctgaagtg caaattgata ggttgatcac aggcagactt caaagtttgc agacatatgt 24540 gactcaacaa ttaattagag ctgcagaaat cagagcttct gctaatcttg ctgctattaa 24600 aatgtcagag tgtgtacttg gacaatcaaa aagagttgat ttttgtggaa agggctatca 24660 tcttatgtcc ttccctcagt cagcacctca tggtgtagtc ttcttgcatg tgacttatgt 24720 ccctgcacaa gaaaagaact tcacaactgc tcctgccatt tgtcatgatg gaaaagcaca 24780 ctttcctcgt gaaggtgtct ttgtttcaaa tggcacacac tggtttgtaa cacaaaggaa 24840 tttttatgaa ccacaaatca ttactacaga caacacattt gtgtctggta actgtgatgt 24900 tgtaatagga attgtcaaca acacagttta tgatcctttg caacctgaat tagactcatt 24960 caaggaggag ttagataaat attttaagaa tcatacatca ccagatgttg atttaggtga 25020 catctctggc attaatgctt catttgtaaa cattcaaaaa gaaattgacc gcctcaatga 25080 ggttgccaag aatttaaatg aatctctcat cgatctccaa gaacttggaa agtatgagca 25140 gtatataaaa tggccatggt acatttggct aggttttata gctggcttga ttgccatagt 25200 aatggtgaca attatgcttt gctgtatgac cagttgctgt agttgtctca agggctgttg 25260 ttcttgtgga tcctgctgca aatttgatga agacgactct gagccagtgc tcaaaggagt 25320 caaattacat tacacataaa cgaacttatg gatttgttta tgagaatctt cacaattgga 25380 actgtaactt tgaagcaagg tgaaatcaag gatgctactc cttcagattt tgttcgcgct 25440 actgcaacga taccgataca agcctcactc cctttcggat ggcttattgt tggcgttgca 25500 cttcttgctg tttttcagag cgcttccaaa atcataaccc tcaaaaagag atggcaacta 25560 gcactctcca agggtgttca ctttgtttgc aacttgctgt tgttgtttgt aacagtttac 25620 tcacaccttt tgctcgttgc tgctggcctt gaagcccctt ttctctatct ttatgcttta 25680 gtctacttct tgcagagtat aaactttgta agaataataa tgaggctttg gctttgctgg 25740 aaatgccgtt ccaaaaaccc attactttat gatgccaact attttctttg ctggcatact 25800 aattgttacg actattgtat accttacaat agtgtaactt cttcaattgt cattacttca 25860 ggtgatggca caacaagtcc tatttctgaa catgactacc agattggtgg ttatactgaa 25920 aaatgggaat ctggagtaaa agactgtgtt gtattacaca gttacttcac ttcagactat 25980 taccagctgt actcaactca attgagtaca gacactggtg ttgaacatgt taccttcttc 26040 atctacaata aaattgttga tgagcctgaa gaacatgtcc aaattcacac aatcgacggt 26100 tcacccggag ttgttaatcc agtaatggaa ccaatttatg atgaaccgac gacgactact 26160 agcgtgcctt tgtaagcaca agctgatgag tacgaactta tgtactcatt cgtttcggaa 26220 gagacaggta cgttaatagt taatagcgta cttctttttc ttgctttcgt ggtattcttg 26280 ctagttacac tagccatcct tactgcgctt cgattgtgtg cgtactgctg caatattgtt 26340 aacgtgagtc ttgtaaaacc ttctttttac gtttactctc gtgttaaaaa tctgaattct 26400 tctagagttc ctgatcttct ggtctaaacg aactaaatat tatattagtt tttctgtttg 26460 gaactttaat tttagccatg gcagattcca acggtactat taccgttgaa gagcttaaaa 26520 agctccttga acaatggaac ctagtaatag gtttcctatt ccttacatgg atttgtcttc 26580 tacaatttgc ctatgccaac aggaataggt ttttgtatat aattaagtta attttcctct 26640 ggctgttatg gccagtaact ttagcttgtt ttgtgcttgc tgctgtttac agaataaatt 26700 ggatcaccgg tggaattgct atcgcaatgg cttgtcttgt aggcttgatg tggctcagct 26760 acttcattgc ttctttcaga ctgtttgcgc gtacgcgttc catgtggtca ttcaatccag 26820 aaactaacat tcttctcaac gtgccactcc atggcactat tctgaccaga ccgcttctag 26880 aaagtgaact cgtaatcgga gctgtgatcc ttcgtggaca tcttcgtatt gctggacacc 26940 atctaggacg ctgtgacatc aaggacctgc ctaaagaaat cactgttgct acatcacgaa 27000 cgctttctta ttacaaattg ggagcttcgc agcgtgtagc aggtgactca ggttttgctg 27060 catacagtcg ctacaggatt ggcaactata aattaaacac agaccattcc agtagcagtg 27120 acaatattgc tttgcttgta cagtaagtga caacagatgt ttcatctcgt tgactttcag 27180 gttactatag cagagatatt actaattatt atgaggactt ttaaagtttc catttggaat 27240 cttgattaca tcataaacct cataattaaa aatttatcta agtcactaac tgagaataaa 27300 tattctcaat tagatgaaga gcaaccaatg gagattgatt aaacgaacat gaaaattatt 27360 cttttcttgg cactgataac actcgctact tgtgagcttt atcactacca agagtgtgtt 27420 agaggtacaa cagtactttt aaaagaacct tgctcttctg gaacatacga gggcaattca 27480 ccatttcatc ctctagctga taacaaattt gcactgactt gctttagcac tcaatttgct 27540 tttgcttgtc ctgacggcgt aaaacacgtc tatcagttac gtgccagatc agtttcacct 27600 aaactgttca tcagacaaga ggaagttcaa gaactttact ctccaatttt tcttattgtt 27660 gcggcaatag tgtttataac actttgcttc acactcaaaa gaaagacaga atgattgaac 27720 tttcattaat tgacttctat ttgtgctttt tagcctttct gctattcctt gttttaatta 27780 tgcttattat cttttggttc tcacttgaac tgcaagatca taatgaaact tgtcacgcct 27840 aaacgaacat gaaatttctt gttttcttag gaatcatcac aactgtagct gcatttcacc 27900 aagaatgtag tttacagtca tgtactcaac atcaaccata tgtagttgat gacccgtgtc 27960 ctattcactt ctattctaaa tggtatatta gagtaggagc tagaaaatca gcacctttaa 28020 ttgaattgtg cgtggatgag gctggttcta aatcacccat tcagtacatc gatatcggta 28080 attatacagt ttcctgttta ccttttacaa ttaattgcca gaaacctaaa ttgggtagtc 28140 ttgtagtgcg ttgttcgttc tatgaagact ttttagagta tcatgacgtt cgtgttgttt 28200 tagatttcat ctaaacgaac aaacaaacta aaatgtctga taatggaccc caaaatcagc 28260 gaaatgcacc ccgcattacg tttggtggac cctcagattc aactggcagt aaccagaatg 28320 gagaacgcag tggggcgcga tcaaaacaac gtcggcccca aggtttaccc aataatactg 28380 cgtcttggtt caccgctctc actcaacatg gcaaggaaga ccttaaattc cctcgaggac 28440 aaggcgttcc aattaacacc aatagcagtc gagatgacca aattggctac taccgaagag 28500 ctaccagacg aattcgtggt ggtgacggta aaatgaaaga tctcagtcca agatggtatt 28560 tctactacct aggaactggg ccagaagctg gacttcccta tggtgctaac aaagacggca 28620 tcatatgggt tgcaactgag ggagccttga atacaccaaa agatcacatt ggcacccgca 28680 atcctgctaa caatgctgca atcgtgctac aacttcctca aggaacaaca ttgccaaaag 28740 gcttctacgc agaagggagc agaggcggca gtcaagcctc ttctcgttcc tcatcacgta 28800 gtcgcaacag ttcaagaaat tcaactccag gcagctctaa acgaacttct cctgctagaa 28860 tggctggcaa tggcggtgat gctgctcttg ctttgctgct gcttgacaga ttgaaccagc 28920 ttgagagcaa aatgtctggt aaaggccaac aacaacaagg ccaaactgtc actaagaaat 28980 ctgctgctga ggcttctaag aagcctcggc aaaaacgtac tgccactaaa gcatacaatg 29040 taacacaagc tttcggcaga cgtggtccag aacaaaccca aggaaatttt ggggaccagg 29100 aactaatcag acaaggaact gattacaaac attggccgca aattgcacaa tttgccccca 29160 gcgcttcagc gttcttcgga atgtcgcgca ttggcatgga agtcacacct tcgggaacgt 29220 ggttgaccta cacaggtgcc atcaaattgg atgacaaaga tccaaatttc aaagatcaag 29280 tcattttgct gaataagcat attgacgcat acaaaacatt cccaccaaca gagcctaaaa 29340 aggacaaaaa gaagaaggct gatgaaactc aagccttacc gcagagacag aagaaacagc 29400 aaactgtgac tcttcttcct gctgcagatt tggatgattt ctccaaacaa ttgcaacaat 29460 ccatgagcag tgctgactca actcaggcct aaactcatgc agaccacaca aggcagatgg 29520 gctatataaa cgttttcgct tttccgttta cgatatatag tctactcttg tgcagaatga 29580 attctcgtaa ctacatagca caagtagatg tagttaactt taatctcaca tagcaatctt 29640 taatcagtgt gtaacattag ggaggacttg aaagagccac cacattttca ccgaggccac 29700 gcggagtacg atcgagtgta cagtgaacaa tgctagggag agctgcctat atggaagagc 29760 cctaatgtgt aaaattaatt ttagtagtgc taaccccatg tgattttaat agcttctta 29819 <210> 21 <211> 1273 <212> PRT <213> SARS-CoV2 <400> 21 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ser Gln Cys Val 1 5 10 15 Asn Phe Thr Asn Arg Thr Gln Leu Pro Ser Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Hes Val Ser Gly Thr Asn Gly Thr Lys Arg Phe Asp 65 70 75 80 Asn Pro Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu 85 90 95 Lys Ser Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser 100 105 110 Lys Thr Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile 115 120 125 Lys Val Cys Glu Phe Gln Phe Cys Asn Tyr Pro Phe Leu Gly Val Tyr 130 135 140 Tyr Hes Lys Asn Asn Lys Ser Trp Met Glu Ser Glu Phe Arg Val Tyr 145 150 155 160 Ser Ser Ala Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu 165 170 175 Met Asp Leu Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Ser Glu Phe 180 185 190 Val Phe Lys Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr 195 200 205 Pro Ile Asn Leu Val Arg Asp Leu Pro Gln Gly Phe Ser Ala Leu Glu 210 215 220 Pro Leu Val Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Thr 225 230 235 240 Leu Leu Ala Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser 245 250 255 Gly Trp Thr Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro 260 265 270 Arg Thr Phe Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala 275 280 285 Val Asp Cys Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys 290 295 300 Ser Phe Thr Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Val 305 310 315 320 Gln Pro Thr Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys 325 330 335 Pro Phe Gly Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala 340 345 350 Trp Asn Arg Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Val Leu 355 360 365 Tyr Asn Ser Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro 370 375 380 Thr Lys Leu Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe 385 390 395 400 Val Ile Arg Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly 405 410 415 Thr Ile Ala Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys 420 425 430 Val Ile Ala Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn 435 440 445 Tyr Asn Tyr Leu Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe 450 455 460 Glu Arg Asp Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys 465 470 475 480 Asn Gly Val Lys Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly 485 490 495 Phe Gln Pro Thr Tyr Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val 500 505 510 Leu Ser Phe Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys 515 520 525 Lys Ser Thr Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn 530 535 540 Gly Leu Thr Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu 545 550 555 560 Pro Phe Gln Gln Phe Gly Arg Asp Ile Ala Asp Thr Thr Asp Ala Val 565 570 575 Arg Asp Pro Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe 580 585 590 Gly Gly Val Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val 595 600 605 Ala Val Leu Tyr Gln Gly Val Asn Cys Thr Glu Val Pro Val Ala Ile 610 615 620 Hes Ala Asp Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser 625 630 635 640 Asn Val Phe Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Tyr Val 645 650 655 Asn Asn Ser Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala 660 665 670 Ser Tyr Gln Thr Gln Thr Asn Ser Pro Arg Arg Ala Arg Ser Val Ala 675 680 685 Ser Gln Ser Ile Ile Ala Tyr Thr Met Ser Leu Gly Ala Glu Asn Ser 690 695 700 Val Ala Tyr Ser Asn Asn Ser Ile Ala Ile Pro Thr Asn Phe Thr Ile 705 710 715 720 Ser Val Thr Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val 725 730 735 Asp Cys Thr Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu 740 745 750 Leu Leu Gln Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr 755 760 765 Gly Ile Ala Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln 770 775 780 Val Lys Gln Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe 785 790 795 800 Asn Phe Ser Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser 805 810 815 Phe Ile Glu Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly 820 825 830 Phe Ile Lys Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp 835 840 845 Leu Ile Cys Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu 850 855 860 Leu Thr Asp Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly 865 870 875 880 Thr Ile Thr Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile 885 890 895 Pro Phe Ala Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr 900 905 910 Gln Asn Val Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn 915 920 925 Ser Ala Ile Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala 930 935 940 Leu Gly Lys Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn 945 950 955 960 Thr Leu Val Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val 965 970 975 Leu Asn Asp Ile Leu Ser Arg Leu Asp Lys Val Glu Ala Glu Val Gln 980 985 990 Ile Asp Arg Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val 995 1000 1005 Thr Gln Gln Leu Ile Arg Ala Ala Glu Ile Arg Ala Ser Ala Asn 1010 1015 1020 Leu Ala Ala Ile Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys 1025 1030 1035 Arg Val Asp Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro 1040 1045 1050 Gln Ser Ala Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val 1055 1060 1065 Pro Ala Gln Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes 1070 1075 1080 Asp Gly Lys Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn 1085 1090 1095 Gly Thr Hes Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln 1100 1105 1110 Ile Ile Thr Thr Asp Asn Thr Phe Val Ser Gly Asn Cys Asp Val 1115 1120 1125 Val Ile Gly Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro 1130 1135 1140 Glu Leu Asp Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn 1145 1150 1155 Hes Thr Ser Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn 1160 1165 1170 Ala Ser Phe Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu 1175 1180 1185 Val Ala Lys Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu 1190 1195 1200 Gly Lys Tyr Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu 1205 1210 1215 Gly Phe Ile Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met 1220 1225 1230 Leu Cys Cys Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys 1235 1240 1245 Ser Cys Gly Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro 1250 1255 1260 Val Leu Lys Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 22 <211> 29883 <212> ADN <213> SARS-CoV2 <220> <221> diferentes_características <222> (29849)..(29883) <223> n es a, c, g, ó t <400> 22 attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct 60 gttctctaaa cgaactttaa aatctgtgtg gctgtcactc ggctgcatgc ttagtgcact 120 cacgcagtat aattaataac taattactgt cgttgacagg acacgagtaa ctcgtctatc 180 ttctgcaggc tgcttacggt ttcgtccgtg ttgcagccga tcatcagcac atctaggttt 240 tgtccgggtg tgaccgaaag gtaagatgga gagccttgtc cctggtttca acgagaaaac 300 acacgtccaa ctcagtttgc ctgttttaca ggttcgcgac gtgctcgtac gtggctttgg 360 agactccgtg gaggaggtct tatcagaggc acgtcaacat cttaaagatg gcacttgtgg 420 cttagtagaa gttgaaaaag gcgttttgcc tcaacttgaa cagccctatg tgttcatcaa 480 acgttcggat gctcgaactg cacctcatgg tcatgttatg gttgagctgg tagcagaact 540 cgaaggcatt cagtacggtc gtagtggtga gacacttggt gtccttgtcc ctcatgtggg 600 cgaaatacca gtggcttacc gcaaggttct tcttcgtaag aacggtaata aaggagctgg 660 tggccatagt tacggcgccg atctaaagtc atttgactta ggcgacgagc ttggcactga 720 tccttatgaa gattttcaag aaaactggaa cactaaacat agcagtggtg ttacccgtga 780 actcatgcgt gagcttaacg gaggggcata cactcgctat gtcgataaca acttctgtgg 840 ccctgatggc taccctcttg agtgcattaa agaccttcta gcacgtgctg gtaaagcttc 900 atgcactttg tctgaacaac tggactttat tgacactaag aggggtgtat actgctgccg 960 tgaacatgag catgaaattg cttggtacac ggaacgttct gaaaagagct atgaattgca 1020 gacacctttt gaaattaaat tggcaaagaa atttgacacc ttcaatgggg aatgtccaaa 1080 ttttgtattt cccttaaatt ccataatcaa gactattcaa ccaagggttg aaaagaaaaa 1140 gcttgatggc tttatgggta gaattcgatc tgtctatcca gttgcgtcac caaatgaatg 1200 caaccaaatg tgcctttcaa ctctcatgaa gtgtgatcat tgtggtgaaa cttcatggca 1260 gacgggcgat tttgttaaag ccacttgcga attttgtggc actgagaatt tgactaaaga 1320 aggtgccact acttgtggtt acttacccca aaatgctgtt gttaaaattt attgtccagc 1380 atgtcacaat tcagaagtag gacctgagca tagtcttgcc gaataccata atgaatctgg 1440 cttgaaaacc attcttcgta agggtggtcg cactattgcc tttggaggct gtgtgttctc 1500 ttatgttggt tgccataaca agtgtgccta ttgggttcca cgtgctagcg ctaacatagg 1560 ttgtaaccat acaggtgttg ttggagaagg ttccgaaggt cttaatgaca accttcttga 1620 aatactccaa aaagagaaag tcaacatcaa tattgttggt gactttaaac ttaatgaaga 1680 gatcgccatt attttggcat ctttttctgc ttccacaagt gcttttgtgg aaactgtgaa 1740 aggtttggat tataaagcat tcaaacaaat tgttgaatcc tgtggtaatt ttaaagttac 1800 aaaaggaaaa gctaaaaaag gtgcctggaa tattggtgaa cagaaatcaa tactgagtcc 1860 tctttatgca tttgcatcag aggctgctcg tgttgtacga tcaattttct cccgcactct 1920 tgaaactgct caaaattctg tgcgtgtttt acagaaggcc gctataacaa tactagatgg 1980 aatttcacag tattcactga gactcattga tgctatgatg ttcacatctg atttggctac 2040 taacaatcta gttgtaatgg cctacattac aggtggtgtt gttcagttga cttcgcagtg 2100 gctaactaac atctttggca ctgtttatga aaaactcaaa cccgtccttg attggcttga 2160 agagaagttt aaggaaggtg tagagtttct tagagacggt tgggaaattg ttaaatttat 2220 ctcaacctgt gcttgtgaaa ttgtcggtgg acaaattgtc acctgtgcaa aggaaattaa 2280 ggagagtgtt cagacattct ttaagcttgt aaataaattt ttggctttgt gtgctgactc 2340 tatcattatt ggtggagcta aacttaaagc cttgaattta ggtgaaacat ttgtcacgca 2400 ctcaaaggga ttgtacagaa agtgtgttaa atccagagaa gaaactggcc tactcatgcc 2460 tctaaaagcc ccaaaagaaa ttatcttctt agagggagaa acacttccca cagaagtgtt 2520 aacagaggaa gttgtcttga aaactggtga tttacaacca ttagaacaac ctactagtga 2580 agctgttgaa gctccattgg ttggtacacc agtttgtatt aacgggctta tgttgctcga 2640 aatcaaagac acagaaaagt actgtgccct tgcacctaat atgatggtaa caaacaatac 2700 cttcacactc aaaggcggtg caccaacaaa ggttactttt ggtgatgaca ctgtgataga 2760 agtgcaaggt tacaagagtg tgaatatcac ttttgaactt gatgaaagga ttgataaagt 2820 acttaatgag aagtgctctg cctatacagt tgaactcggt acagaagtaa atgagttcgc 2880 ctgtgttgtg gcagatgctg tcataaaaac tttgcaacca gtatctgaat tacttacacc 2940 actgggcatt gatttagatg agtggagtat ggctacatac tacttatttg atgagtctgg 3000 tgagtttaaa ttggcttcac atatgtattg ttctttttac cctccagatg aggatgaaga 3060 agaaggtgat tgtgaagaag aagagtttga gccatcaact caatatgagt atggtactga 3120 agatgattac caaggtaaac ctttggaatt tggtgccact tctgctgctc ttcaacctga 3180 agaagagcaa gaagaagatt ggttagatga tgatagtcaa caaactgttg gtcaacaaga 3240 cggcagtgag gacaatcaga caactattat tcaaacaatt gttgaggttc aacctcaatt 3300 agagatggaa cttacaccag ttgttcagac tattgaagtg aatagtttta gtggttattt 3360 aaaacttact gacaatgtat acattaaaaa tgcagacatt gtggaagaag ctaaaaaggt 3420 aaaaccaaca gtggttgtta atgcagccaa tgtttacctt aaacatggag gaggtgttgc 3480 aggagcctta aataaggcta ctaacaatgc catgcaagtt gaatctgatg attacatagc 3540 tactaatgga ccacttaaag tgggtggtag ttgtgtttta agcggacaca atcttgctaa 3600 acactgtctt catgttgtcg gcccaaatgt taacaaaggt gaagacattc aacttcttaa 3660 gagtgcttat gaaaatttta atcagcacga agttctactt gcaccattat tatcagctgg 3720 tatttttggt gctgacccta tacattcttt aagagtttgt gtagatactg ttcgcacaaa 3780 tgtctactta gctgtctttg ataaaaatct ctatgacaaa cttgtttcaa gctttttgga 3840 aatgaagagt gaaaagcaag ttgaacaaaa gatcgctgag attcctaaag aggaagttaa 3900 gccatttata actgaaagta aaccttcagt tgaacagaga aaacaagatg ataagaaaat 3960 caaagcttgt gttgaagaag ttacaacaac tctggaagaa actaagttcc tcacagaaaa 4020 cttgttactt tatattgaca ttaatggcaa tcttcatcca gattctgcca ctcttgttag 4080 tgacattgac atcactttct taaagaaaga tgctccatat atagtgggtg atgttgttca 4140 agagggtgtt ttaactgctg tggttatacc tactaaaaag gctggtggca ctactgaaat 4200 gctagcgaaa gctttgagaa aagtgccaac agacaattat ataaccactt acccgggtca 4260 gggtttaaat ggttacactg tagaggaggc aaagacagtg cttaaaaagt gtaaaagtgc 4320 cttttacatt ctaccatcta ttatctctaa tgagaagcaa gaaattcttg gaactgtttc 4380 ttggaatttg cgagaaatgc ttgcacatgc agaagaaaca cgcaaattaa tgcctgtctg 4440 tgtggaaact aaagccatag tttcaactat acagcgtaaa tataagggta ttaaaataca 4500 agagggtgtg gttgattatg gtgctagatt ttacttttac accagtaaaa caactgtagc 4560 gtcacttatc aacacactta acgatctaaa tgaaactctt gttacaatgc cacttggcta 4620 tgtaacacat ggcttaaatt tggaagaagc tgctcggtat atgagatctc tcaaagtgcc 4680 agctacagtt tctgtttctt cacctgatgc tgttacagcg tataatggtt atcttacttc 4740 ttcttctaaa acacctgaag aacattttat tgaaaccatc tcacttgctg gttcctataa 4800 agattggtcc tattctggac aatctacaca actaggtata gaatttctta agagaggtga 4860 taaaagtgta tattacacta gtaatcctac cacattccac ctagatggtg aagttatcac 4920 ctttgacaat cttaagacac ttctttcttt gagagaagtg aggactatta aggtgtttac 4980 aacagtagac aacattaatc tccacacgca agttgtggac atgtcaatga catatggaca 5040 acagtttggt ccaacttatt tggatggagc tgatgttact aaaataaaac ctcataattc 5100 acatgaaggt aaaacatttt atgttttacc taatgatgac actctacgtg ttgaggcttt 5160 tgagtactac cacacaactg atcctagttt tctgggtagg tacatgtcag cattaaatca 5220 cactaaaaag tggaaatacc cacaagttaa tggtttaact tctattaaat gggcagataa 5280 caactgttat cttgccactg cattgttaac actccaacaa atagagttga agtttaatcc 5340 acctgctcta caagatgctt attacagagc aagggctggt gaagctgata acttttgtgc 5400 acttatctta gcctactgta ataagacagt aggtgagtta ggtgatgtta gagaaacaat 5460 gagttacttg tttcaacatg ccaatttaga ttcttgcaaa agagtcttga acgtggtgtg 5520 taaaacttgt ggacaacagc agacaaccct taagggtgta gaagctgtta tgtacatggg 5580 cacactttct tatgaacaat ttaagaaagg tgttcagata ccttgtacgt gtggtaaaca 5640 agctacaaaa tatctagtac aacaggagtc accttttgtt atgatgtcag caccacctgc 5700 tcagtatgaa cttaagcatg gtacatttac ttgtgctagt gagtacactg gtaattacca 5760 gtgtggtcac tataaacata taacttctaa agaaactttg tattgcatag acggtgcttt 5820 acttacaaag tcctcagaat acaaaggtcc tattacggat gttttctaca aagaaaacag 5880 ttacacaaca accataaaac cagttactta taaattggat ggtgttgttt gtacagaaat 5940 tgaccctaag ttggacaatt attataagaa agacaattct tattttacag agcaaccaat 6000 tgatcttgta ccaaaccaac catatccaaa cgcaagcttc gataatttta agtttgtatg 6060 tgataatatc aaatttgctg atgatttaaa ccagttaact ggttataaga aacctgcttc 6120 aagagagctt aaagttacat ttttccctga cttaaatggt gatgtggtgg ctattgatta 6180 taaacactac acaccctctt ttaagaaagg agctaaattg ttacataaac ctattgtttg 6240 gcatgttaac aatgcaacta ataaagccac gtataaacca aatacctggt gtatacgttg 6300 tctttggagc acaaaaccag ttgaaacatc aaattcgttt gatgtactga agtcagagga 6360 cgcgcaggga atggataatc ttgcctgcga agatctaaaa ccagtctctg aagaagtagt 6420 ggaaaatcct accatacaga aagacgttct tgagtgtaat gtgaaaacta ccgaagttgt 6480 aggagacatt atacttaaac cagcaaataa tagtttaaaa attacagaag aggttggcca 6540 cacagatcta atggctgctt atgtagacaa ttctagtctt actattaaga aacctaatga 6600 attatctaga gtattaggtt tgaaaaccct tgttactcat ggtttagctg ctgttaatag 6660 tgtcccttgg gatactatag ctaattatgc taagcctttt cttaacaaag ttgttagtac 6720 aactactaac atagttacac ggtgtttaaa ccgtgtttgt actaattata tgccttattt 6780 ctttacttta ttgctacaat tgtgtacttt tactagaagt acaaattcta gaattaaagc 6840 atctatgccg actactatag caaagaatac tgttaagagt gtcggtaaat tttgtctaga 6900 ggcttcattt aattatttga agtcacctaa tttttctaaa ctgataaata ttacaatttg 6960 gtttttacta ttaagtgttt gcctaggttc tttaatctac tcaaccgctg ctttaggtgt 7020 tttaatgtct aatttaggca tgccttctta ctgtactggt tacagagaag gctatttgaa 7080 ctctactaat gtcactattg caacctactg tactggttct ataccttgta gtgtttgtct 7140 tagtggttta gattctttag acacctatcc ttctttagaa actatacaaa ttaccatttc 7200 atcttttaaa tgggatttaa ctgcttttgg cttagttgca gagtggtttt tggcatatat 7260 tcttttcact aggtttttct atgtacttgg attggctgca atcatgcaat tgtttttcag 7320 ctattttgca gtacatttta ttagtaattc ttggcttatg tggttaataa ttaatcttgt 7380 acaaatggcc ccgatttcag ctatggttag aatgtacatc ttctttgcat cattttatta 7440 tgtatggaaa agttatgtgc atgttgtaga cggttgtaat tcatcaactt gtatgatgtg 7500 ttacaaacgt aatagagcaa caagagtcga atgtacaact attgttaatg gtgttagaag 7560 gtccttttat gtctatgcta atggaggtaa aggcttttgc aaactacaca attggaattg 7620 tgttaattgt gatacattct gtgctggtag tacatttatt agtgatgaag ttgcgagaga 7680 cttgtcacta cagtttaaaa gaccaataaa tcctactgac cagtcttctt acatcgttga 7740 tagtgttaca gtgaagaatg gttccatcca tctttacttt gataaagctg gtcaaaagac 7800 ttatgaaaga cattctctct ctcattttgt taacttagac aacctgagag ctaataacac 7860 taaaggttca ttgcctatta atgttatagt ttttgatggt aaatcaaaat gtgaagaatc 7920 atctgcaaaa tcagcgtctg tttactacag tcagcttatg tgtcaaccta tactgttact 7980 agatcaggca ttagtgtctg atgttggtga tagtgcggaa gttgcagtta aaatgtttga 8040 tgcttacgtt aatacgtttt catcaacttt taacgtacca atggaaaaac tcaaaacact 8100 agttgcaact gcagaagctg aacttgcaaa gaatgtgtcc ttagacaatg tcttatctac 8160 ttttatttca gcagctcggc aagggtttgt tgattcagat gtagaaacta aagatgttgt 8220 tgaatgtctt aaattgtcac atcaatctga catagaagtt actggcgata gttgtaataa 8280 ctatatgctc acctataaca aagttgaaaa catgacaccc cgtgaccttg gtgcttgtat 8340 tgactgtagt gcgcgtcata ttaatgcgca ggtagcaaaa agtcacaaca ttgctttgat 8400 atggaacgtt aaagatttca tgtcattgtc tgaacaacta cgaaaacaaa tacgtagtgc 8460 tgctaaaaag aataacttac cttttaagtt gacatgtgca actactagac aagttgttaa 8520 tgttgtaaca acaaagatag cacttaaggg tggtaaaatt gttaataatt ggttgaagca 8580 gttaattaaa gttacacttg tgttcctttt tgttgctgct attttctatt taataacacc 8640 tgttcatgtc atgtctaaac atactgactt ttcaagtgaa atcataggat acaaggctat 8700 tgatggtggt gtcactcgtg acatagcatc tacagatact tgttttgcta acaaacatgc 8760 tgattttgac acatggttta gccagcgtgg tggtagttat actaatgaca aagcttgccc 8820 attgattgct gcagtcataa caagagaagt gggttttgtc gtgcctggtt tgcctggcac 8880 gatattacgc acaactaatg gtgacttttt gcatttctta cctagagttt ttagtgcagt 8940 tggtaacatc tgttacacac catcaaaact tatagagtac actgactttg caacatcagc 9000 ttgtgttttg gctgctgaat gtacaatttt taaagatgct tctggtaagc cagtaccata 9060 ttgttatgat accaatgtac tagaaggttc tgttgcttat gaaagtttac gccctgacac 9120 acgttatgtg ctcatggatg gctctattat tcaatttcct aacacctacc ttgaaggttc 9180 tgttagagtg gtaacaactt ttgattctga gtactgtagg cacggcactt gtgaaagatc 9240 agaagctggt gtttgtgtat ctactagtgg tagatgggta cttaacaatg attattacag 9300 atctttacca ggagttttct gtggtgtaga tgctgtaaat ttacttacta atatgtttac 9360 accactaatt caacctattg gtgctttgga catatcagca tctatagtag ctggtggtat 9420 tgtagctatc gtagtaacat gccttgccta ctattttatg aggtttagaa gagcttttgg 9480 tgaatacagt catgtagttg cctttaatac tttactattc cttatgtcat tcactgtact 9540 ctgtttaaca ccagtttact cattcttacc tggtgtttat tctgttattt acttgtactt 9600 gacattttat cttactaatg atgtttcttt tttagcacat attcagtgga tggttatgtt 9660 cacaccttta gtacctttct ggataacaat tgcttatatc atttgtattt ccacaaagca 9720 tttctattgg ttctttagta attacctaaa gagacgtgta gtctttaatg gtgtttcctt 9780 tagtactttt gaagaagctg cgctgtgcac ctttttgtta aataaagaaa tgtatctaaa 9840 gttgcgtagt gatgtgctat tacctcttac gcaatataat agatacttag ctctttataa 9900 taagtacaag tattttagtg gagcaatgga tacaactagc tacagagaag ctgcttgttg 9960 tcatctcgca aaggctctca atgacttcag taactcaggt tctgatgttc tttaccaacc 10020 accacaaacc tctatcacct cagctgtttt gcagagtggt tttagaaaaa tggcattccc 10080 atctggtaaa gttgagggtt gtatggtaca agtaacttgt ggtacaacta cacttaacgg 10140 tctttggctt gatgacgtag tttactgtcc aagacatgtg atctgcacct ctgaagacat 10200 gcttaaccct aattatgaag atttactcat tcgtaagtct aatcataatt tcttggtaca 10260 ggctggtaat gttcaactca gggttattgg acattctatg caaaattgtg tacttaagct 10320 taaggttgat acagccaatc ctaagacacc taagtataag tttgttcgca ttcaaccagg 10380 acagactttt tcagtgttag cttgttacaa tggttcacca tctggtgttt accaatgtgc 10440 tatgaggccc aatttcacta ttaagggttc attccttaat ggttcatgtg gtagtgttgg 10500 ttttaacata gattatgact gtgtctcttt ttgttacatg caccatatgg aattaccaac 10560 tggagttcat gctggcacag acttagaagg taacttttat ggaccttttg ttgacaggca 10620 aacagcacaa gcagctggta cggacacaac tattacagtt aatgttttag cttggttgta 10680 cgctgctgtt ataaatggag acaggtggtt tctcaatcga tttaccacaa ctcttaatga 10740 ctttaacctt gtggctatga agtacaatta tgaacctcta acacaagacc atgttgacat 10800 actaggacct ctttctgctc aaactggaat tgccgtttta gatatgtgtg cttcattaaa 10860 agaattactg caaaatggta tgaatggacg taccatattg ggtagtgctt tattagaaga 10920 tgaatttaca ccttttgatg ttgttagaca atgctcaggt gttactttcc aaagtgcagt 10980 gaaaagaaca atcaagggta cacaccactg gttgttactc acaattttga cttcactttt 11040 agttttagtc cagagtactc aatggtcttt gttctttttt ttgtatgaaa atgccttttt 11100 accttttgct atgggtatta ttgctatgtc tgcttttgca atgatgtttg tcaaacataa 11160 gcatgcattt ctctgtttgt ttttgttacc ttctcttgcc actgtagctt attttaatat 11220 ggtctatatg cctgctagtt gggtgatgcg tattatgaca tggttggata tggttgatac 11280 tagtttgaag ctaaaagact gtgttatgta tgcatcagct gtagtgttac taatccttat 11340 gacagcaaga actgtgtatg atgatggtgc taggagagtg tggacactta tgaatgtctt 11400 gacactcgtt tataaagttt attatggtaa tgctttagat caagccattt ccatgtgggc 11460 tcttataatc tctgttactt ctaactactc aggtgtagtt acaactgtca tgtttttggc 11520 cagaggtatt gtttttatgt gtgttgagta ttgccctatt ttcttcataa ctggtaatac 11580 acttcagtgt ataatgctag tttattgttt cttaggctat ttttgtactt gttactttgg 11640 cctcttttgt ttactcaacc gctactttag actgactctt ggtgtttatg attacttagt 11700 ttctacacag gagtttagat atatgaattc acagggacta ctcccaccca agaatagcat 11760 agatgccttc aaactcaaca ttaaattgtt gggtgttggt ggcaaacctt gtatcaaagt 11820 agccactgta cagtctaaaa tgtcagatgt aaagtgcaca tcartagtct tactctcagt 11880 tttgcaacaa ctcagagtag aatcatcatc taaattgtgg gctcaatgtg tccagttaca 11940 caatgacatt ctcttagcta aagatactac tgaagccttt gaaaaaatgg tttcactact 12000 ttctgttttg ctttccatgc agggtgctgt agacataaac aagctttgtg aagaaatgct 12060 ggacaacagg gcaaccttac aagctatagc ctcagagttt agttcccttc catcatatgc 12120 agcttttgct actgctcaag aagcttatga gcaggctgtt gctaatggtg attctgaagt 12180 tgttcttaaa aagttgaaga agtctttgaa tgtggctaaa tctgaatttg accgtgatgc 12240 agccatgcaa cgtaagttgg aaaagatggc tgatcaagct atgacccaaa tgtataaaca 12300 ggctagatct gaggacaaga gggcaaaagt tactagtgct atgcagacaa tgcttttcac 12360 tatgcttaga aagttggata atgatgcact caacaacatt atcaacaatg caagagatgg 12420 ttgtgttccc ttgaacataa tacctcttac aacagcagcc aaactaatgg ttgtcatacc 12480 agactataac acatataaaa atacgtgtga tggtacaaca tttacttatg catcagcatt 12540 gtgggaaatc caacaggttg tagatgcaga tagtaaaatt gttcaactta gtgaaattag 12600 tatggacaat tcacctaatt tagcatggcc tcttattgta acagctttaa gggccaattc 12660 tgctgtcaaa ttacagaata atgagcttag tcctgttgca ctacgacaga tgtcttgtgc 12720 tgccggtact acacaaactg cttgcactga tgacaatgcg ttagcttact acaacacaac 12780 aaagggaggt aggtttgtac ttgcactgtt atccgattta caggatttga aatgggctag 12840 attccctaag agtgatggaa ctggtactat ctatacagaa ctggaaccac cttgtaggtt 12900 tgttacagac acacctaaag gtcctaaagt gaagtattta tactttatta aaggattaaa 12960 caacctaaat agaggtatgg tacttggtag tttagctgcc acagtacgtc tacaagctgg 13020 taatgcaaca gaagtgcctg ccaattcaac tgtattatct ttctgtgctt ttgctgtaga 13080 tgctgctaaa gcttacaaag attatctagc tagtggggga caaccaatca ctaattgtgt 13140 taagatgttg tgtacacaca ctggtactgg tcaggcaata acagttacac cggaagccaa 13200 tatggatcaa gaatcctttg gtggtgcatc gtgttgtctg tactgccgtt gccacataga 13260 tcatccaaat cctaaaggat tttgtgactt aaaaggtaag tatgtacaaa tacctacaac 13320 ttgtgctaat gaccctgtgg gttttacact taaaaacaca gtctgtaccg tctgcggtat 13380 gtggaaaggt tatggctgta gttgtgatca actccgcgaa cccatgcttc agtcagctga 13440 tgcacaatcg tttttaaacg ggtttgcggt gtaagtgcag cccgtcttac accgtgcggc 13500 acaggcacta gtactgatgt cgtatacagg gcttttgaca tctacaatga taaagtagct 13560 ggttttgcta aattcctaaa aactaattgt tgtcgcttcc aagaaaagga cgaagatgac 13620 aatttaattg attcttactt tgtagttaag agacacactt tctctaacta ccaacatgaa 13680 gaaacaattt ataatttact taaggattgt ccagctgttg ctaaacatga cttctttaag 13740 tttagaatag acggtgacat ggtaccacat atatcacgtc aacgtcttac taaatacaca 13800 atggcagacc tcgtctatgc tttaaggcat tttgatgaag gtaattgtga cacattaaaa 13860 gaaatacttg tcacatacaa ttgttgtgat gatgattatt tcaataaaaa ggactggtat 13920 gattttgtag aaaacccaga tatattacgc gtatacgcca acttaggtga acgtgtacgc 13980 caagctttgt taaaaacagt acaattctgt gatgccatgc gaaatgctgg tattgttggt 14040 gtactgacat tagataatca agatctcaat ggtaactggt atgatttcgg tgatttcata 14100 caaaccacgc caggtagtgg agttcctgtt gtagattctt attattcatt gttaatgcct 14160 atattaacct tgaccagggc tttaactgca gagtcacatg ttgacactga cttaacaaag 14220 ccttacatta agtgggattt gttaaaatat gacttcacgg aagagaggtt aaaactcttt 14280 gaccgttatt ttaaatattg ggatcagaca taccacccaa attgtgttaa ctgtttggat 14340 gacagatgca ttctgcattg tgcaaacttt aatgttttat tctctacagt gttcccactt 14400 acaagttttg gaccactagt gagaaaaata tttgttgatg gtgttccatt tgtagtttca 14460 actggatacc acttcagaga gctaggtgtt gtacataatc aggatgtaaa cttacatagc 14520 tctagactta gttttaagga attacttgtg tatgctgctg accctgctat gcacgctgct 14580 tctggtaatc tattactaga taaacgcact acgtgctttt cagtagctgc acttactaac 14640 aatgttgctt ttcaaactgt caaacctggt aattttaaca aagacttcta tgactttgct 14700 gtgtctaagg gtttctttaa ggaaggaagt tctgttgaat taaaacactt cttctttgct 14760 caggatggta atgctgctat cagcgattat gactactatc gttataatct accaacaatg 14820 tgtgatatca gacaactact atttgtagtt gaagttgttg ataagtactt tgattgttac 14880 gatggtggct gtattaatgc taaccaagtc atcgtcaaca acctagacaa atcagctggt 14940 tttccattta ataaatgggg taaggctaga ctttattatg attcaatgag ttatgaggat 15000 caagatgcac ttttcgcata tacaaaacgt aatgtcatcc ctactataac tcaaatgaat 15060 cttaagtatg ccattagtgc aaagaataga gctcgcaccg tagctggtgt ctctatctgt 15120 agtactatga ccaatagaca gtttcatcaa aaattattga aatcaatagc cgccactaga 15180 ggagctactg tagtaattgg aacaagcaaa ttctatggtg gttggcacaa catgttaaaa 15240 actgtttata gtgatgtaga aaaccctcat cttatgggtt gggattatcc taaatgtgat 15300 agagccatgc ctaacatgct tagaattatg gcctcacttg ttcttgctcg caaacataca 15360 acgtgttgta gcttgtcaca ccgtttctat agattagcta atgagtgtgc tcaagtattg 15420 agtgaaatgg tcatgtgtgg cggttcacta tatgttaaac caggtggaac ctcatcagga 15480 gatgccacaa ctgcttatgc taatagtgtt tttaacattt gtcaagctgt cacggccaat 15540 gttaatgcac ttttatctac tgatggtaac aaaattgccg ataagtatgt ccgcaattta 15600 caacacagac tttatgagtg tctctataga aatagagatg ttgacacaga ctttgtgaat 15660 gagttttacg catatttgcg taaacatttc tcaatgatga tactctctga cgatgctgtt 15720 gtgtgtttca atagcactta tgcatctcaa ggtctagtgg ctagcataaa gaactttaag 15780 tcagttcttt attatcaaaa caatgttttt atgtctgaag caaaatgttg gactgagact 15840 gaccttacta aaggacctca tgaattttgc tctcaacata caatgctagt taaacagggt 15900 gatgattatg tgtaccttcc ttacccagat ccatcaagaa tcctaggggc cggctgtttt 15960 gtagatgata tcgtaaaaac agatggtaca cttatgattg aacggttcgt gtctttagct 16020 atagatgctt acccacttac taaacatcct aatcaggagt atgctgatgt ctttcatttg 16080 tacttacaat acataagaaa gctacatgat gagttaacag gacacatgtt agacatgtat 16140 tctgttatgc ttactaatga taacacctca aggtattggg aacctgagtt ttatgaggct 16200 atgtacacac cgcatacagt cttacaggct gttggggctt gtgttctttg caattcacag 16260 acttcattaa gatgtggtgc ttgcatacgt agaccattct tatgttgtaa atgctgttac 16320 gaccatgtca tatcaacatc acataaatta gtcttgtctg ttaatccgta tgtttgcaat 16380 gctccaggtt gtgatgtcac agatgtgact caactttact taggaggtat gagctattat 16440 tgtaaatcac ataaaccacc cattagtttt ccattgtgtg ctaatggaca agtttttggt 16500 ttatataaaa atacatgtgt tggtagcgat aatgttactg actttaatgc aattgcaaca 16560 tgtgactgga caaatgctgg tgattacatt ttagctaaca cctgtactga aagactcaag 16620 ctttttgcag cagaaacgct caaagctact gaggagacat ttaaactgtc ttatggtatt 16680 gctactgtac gtgaagtgct gtctgacaga gaattacatc tttcatggga agttggtaaa 16740 cctagaccac cacttaaccg aaattatgtc tttactggtt atcgtgtaac taaaaacagt 16800 aaagtacaaa taggagagta cacctttgaa aaaggtgact atggtgatgc tgttgtttac 16860 cgaggtacaa caacttacaa attaaatgtt ggtgattatt ttgtgctgac atcacataca 16920 gtaatgccat taagtgcacc tacactagtg ccacaagagc actatgttag aattactggc 16980 ttatacccaa cactcaatat ctcagatgag ttttctagca atgttgcaaa ttatcaaaag 17040 gttggtatgc aaaagtattc tacactccag ggaccacctg gtactggtaa gagtcatttt 17100 gctattggcc tagctctcta ctacccttct gctcgcatag tgtatacagc ttgctctcat 17160 gccgctgttg atgcactatg tgagaaggca ttaaaatatt tgcctataga taaatgtagt 17220 agaattatac ctgcacgtgc tcgtgtagag tgttttgata aattcaaagt gaattcaaca 17280 ttagaacagt atgtcttttg tactgtaaat gcattgcctg agacgacagc agatatagtt 17340 gtctttgatg aaatttcaat ggccacaaat tatgatttga gtgttgtcaa tgccagatta 17400 cgtgctaagc actatgtgta cattggcgac cctgctcaat tacctgcacc acgcacattg 17460 ctaactaagg gcacactaga accagaatat ttcaattcag tgtgtagact tatgaaaact 17520 ataggtccag acatgttcct cggaacttgt cggcgttgtc ctgctgaaat tgttgacact 17580 gtgagtgctt tggtttatga taataggctt aaagcacata aagacaaatc agctcaatgc 17640 tttaaaatgt tttataaggg tgttatcacg catgatgttt catctgcaat taacaggcca 17700 caaataggcg tggtaagaga attccttaca cgtaaccctg cttggagaaa agctgtcttt 17760 atttcacctt ataattcaca gaatgctgta gcctcaaaga ttttgggact accaactcaa 17820 actgttgatt catcacaggg ctcagaatat gactatgtca tattcactca aaccactgaa 17880 acagctcact cttgtaatgt aaacagattt aatgttgcta ttaccagagc aaaagtaggc 17940 atactttgca taatgtctga tagagacctt tatgacaagt tgcaatttac aagtcttgaa 18000 attccacgta ggaatgtggc aactttacaa gctgaaaatg taacaggact ctttaaagat 18060 tgtagtaagg taatcactgg gttacatcct acacaggcac ctacacacct cagtgttgac 18120 actaaattca aaactgaagg tttatgtgtt gacatacctg gcatacctaa ggacatgacc 18180 tatagaagac tcatctctat gatgggtttt aaaatgaatt atcaagttaa tggttaccct 18240 aacatgttta tcacccgcga agaagctata agacatgtac gtgcatggat tggcttcgat 18300 gtcgaggggt gtcatgctac tagagaagct gttggtacca atttaccttt acagctaggt 18360 ttttctacag gtgttaacct agttgctgta cctacaggtt atgttgatac acctaataat 18420 acagattttt ccagagttag tgctaaacca ccgcctggag atcaatttaa acacctcata 18480 ccacttatgt acaaaggact tccttggaat gtagtgcgta taaagattgt acaaatgtta 18540 agtgacacac ttaaaaatct ctctgacaga gtcgtatttg tcttatgggc acatggcttt 18600 gagttgacat ctatgaagta ttttgtgaaa ataggacctg agcgcacctg ttgtctatgt 18660 gatagacgtg ccacatgctt ttccactgct tcagacactt atgcctgttg gcatcattct 18720 attggatttg attacgtcta taatccgttt atgattgatg ttcaacaatg gggttttaca 18780 ggtaacctac aaagcaacca tgatctgtat tgtcaagtcc atggtaatgc acatgtagct 18840 agttgtgatg caatcatgac taggtgtcta gctgtccacg agtgctttgt taagcgtgtt 18900 gactggacta ttgaatatcc tataattggt gatgaactga agattaatgc ggcttgtaga 18960 aaggttcaac acatggttgt taaagctgca ttattagcag acaaattccc agttcttcac 19020 gacattggta accctaaagc tattaagtgt gtacctcaag ctgatgtagg atggaagttc 19080 tatgatgcac agccttgtag tgacaaagct tataaaatag aagaattatt ctattcttat 19140 gccacacatt ctgacaaatt cacagatggt gtatgcctat tttggaattg caatgtcgat 19200 agatatcctg ctaattccat tgtttgtaga tttgacacta gagtgctatc taaccttaac 19260 ttgcctggtt gtgatggtgg cagtttgtat gtaaataaac atgcattcca cacaccagct 19320 tttgataaaa gtgcttttgt taatttaaaa caattaccat ttttctatta ctctgacagt 19380 ccatgtgagt ctcatggaaa acaagtagtg tcagatatag attatgtacc actaaagtct 19440 gctacgtgta taacacgttg caatttaggt ggtgctgtct gtagacatca tgctaatgag 19500 tacagattgt atctcgatgc ttataacatg atgatctcag ctggctttag cttgtgggtt 19560 tacaaacaat ttgatactta taacctctgg aacactttta caagacttca gagtttagaa 19620 aatgtggctt ttaatgttgt aaataaggga cactttgatg gacaacaggg tgaagtacca 19680 gtttctatca ttaataacac tgtttacaca aaagttgatg gtgttgatgt agaattgttt 19740 gaaaataaaa caacattacc tgttaatgta gcatttgagc tttgggctaa gcgcaacatt 19800 aaaccagtac cagaggtgaa aatactcaat aatttgggtg tggatattgc tgctaatact 19860 gtgatctggg actacaaaag agatgctcca gcacatatat ctactattgg tgtttgttct 19920 atgactgaca tagccaagaa accaactgaa acgatttgtg caccactcac tgtctttttt 19980 gatggtagag ttgatggtca agtagactta tttagaaatg cccgtaatgg tgttcttatt 20040 acagaaggta gtgttaaagg tttacaacca tctgtaggtc ccaaacaagc tagtcttaat 20100 ggagtcacat taattggaga agccgtaaaa acacagttca attattataa gaaagttgat 20160 ggtgttgtcc aacaattacc tgaaacttac tttactcaga gtagaaattt acaagaattt 20220 aaacccagga gtcaaatgga aattgatttc ttagaattag ctatggatga attcattgaa 20280 cggtataaat tagaaggcta tgccttcgaa catatcgttt atggagattt tagtcatagt 20340 cagttaggtg gtttacatct actgattgga ctagctaaac gttttaagga atcacctttt 20400 gaattagaag attttattcc tatggacagt acagttaaaa actatttcat aacagatgcg 20460 caaacaggtt catctaagtg tgtgtgttct gttattgatt tattacttga tgattttgtt 20520 gaaataataa aatcccaaga tttatctgta gtttctaagg ttgtcaaagt gactattgac 20580 tatacagaaa tttcatttat gctttgtgta aagatggcca tgtagaaaca ttttacccaa 20640 aattacaatc tagtcaagcg tggcaaccgg gtgttgctat gcctaatctt tacaaaatgc 20700 aaagaatgct attagaaaag tgtgaccttc aaaattatgg tgatagtgca acattaccta 20760 aaggcataat gatgaatgtc gcaaaatata ctcaactgtg tcaatattta aacacattaa 20820 cattagctgt accctataat atgagagtta tacattttgg tgctggttct gataaaggag 20880 ttgcaccagg tacagctgtt ttaagacagt ggttgcctac gggtacgctg cttgtcgatt 20940 cagatcttaa tgactttgtc tctgatgcag attcaacttt gattggtgat tgtgcaactg 21000 tacatacagc taataaatgg gatctcatta ttagtgatat gtacgaccct aagactaaaa 21060 atgttacaaa agaaaatgac tctaaagagg gttttttcac ttacatttgt gggtttatac 21120 aacaaaagct agctcttgga ggttccgtgg ctataaagat aacagaacat tcttggaatg 21180 ctgatcttta taagctcatg ggacacttcg catggtggac agcctttgtt actaatgtga 21240 atgcgtcatc atctgaagca tttttaattg gatgtaatta tcttggcaaa ccacgcgaac 21300 aaatagatgg ttatgtcatg catgcaaatt acatattttg gaggaataca aatccaattc 21360 agttgtcttc ctattcttta tttgacatga gtaaatttcc ccttaaatta aggggtactg 21420 ctgttatgtc tttaaaagaa ggtcaaatca atgatatgat tttatctctt cttagtaaag 21480 gtagacttat aattagagaa aacaacagag ttgttatttc tagtgatgtt cttgttaaca 21540 actaaacgaa caatgtttgt ttttcttgtt ttattgccac tagtctctag tcagtgtgtt 21600 aatcttacaa ccagaactca attaccccct gcatacacta attctttcac acgtggtgtt 21660 tattaccctg acaaagtttt cagatcctca gttttacatt caactcagga cttgttctta 21720 cctttctttt ccaatgttac ttggttccat gctatctctg ggaccaatgg tactaagagg 21780 tttgataacc ctgtcctacc atttaatgat ggtgtttatt ttgcttccac tgagaagtct 21840 aacataataa gaggctggat ttttggtact actttagatt cgaagaccca gtccctactt 21900 attgttaata acgctactaa tgttgttatt aaagtctgtg aatttcaatt ttgtaatgat 21960 ccatttttgg gtgtttacca caaaaacaac aaaagttgga tggaaagtga gttcagagtt 22020 tattctagtg cgaataattg cacttttgaa tatgtctctc agccttttct tatggacctt 22080 gaaggaaaac agggtaattt caaaaatctt agggaatttg tgtttaagaa tattgatggt 22140 tattttaaaa tatattctaa gcacacgcct attaatttag tgcgtgatct ccctcagggt 22200 ttttcggctt tagaaccatt ggtagatttg ccaataggta ttaacatcac taggtttcaa 22260 actttacttg ctttacatag aagttatttg actcctggtg attcttcttc aggttggaca 22320 gctggtgctg cagcttatta tgtgggttat cttcaaccta ggacttttct attaaaatat 22380 aatgaaaatg gaaccattac agatgctgta gactgtgcac ttgaccctct ctcagaaaca 22440 aagtgtacgt tgaaatcctt cactgtagaa aaaggaatct atcaaacttc taactttaga 22500 gtccaaccaa cagaatctat tgttagattt cctaatatta caaacttgtg cccttttggt 22560 gaagttttta acgccaccag atttgcatct gtttatgctt ggaacaggaa gagaatcagc 22620 aactgtgttg ctgattattc tgtcctatat aattccgcat cattttccac ttttaagtgt 22680 tatggagtgt ctcctactaa attaaatgat ctctgcttta ctaatgtcta tgcagattca 22740 tttgtaatta gaggtgatga agtcagacaa atcgctccag ggcaaactgg aaagattgct 22800 gattataatt ataaattacc agatgatttt acaggctgcg ttatagcttg gaattctaac 22860 aatcttgatt ctaaggttgg tggtaattat aattacctgt atagattgtt taggaagtct 22920 aatctcaaac cttttgagag agatatttca actgaaatct atcaggccgg tagcacacct 22980 tgtaatggtg ttgaaggttt taattgttac tttcctttac aatcatatgg tttccaaccc 23040 acttatggtg ttggttacca accatacaga gtagtagtac tttcttttga acttctacat 23100 gcaccagcaa ctgtttgtgg acctaaaaag tctactaatt tggttaaaaa caaatgtgtc 23160 aatttcaact tcaatggttt aacaggcaca ggtgttctta ctgagtctaa caaaaagttt 23220 ctgcctttcc aacaatttgg cagagacatt gatgacacta ctgatgctgt ccgtgatcca 23280 cagacacttg agattcttga cattacacca tgttcttttg gtggtgtcag tgttataaca 23340 ccaggaacaa atacttctaa ccaggttgct gttctttatc agggtgttaa ctgcacagaa 23400 gtccctgttg ctattcatgc agatcaactt actcctactt ggcgtgttta ttctacaggt 23460 tctaatgttt ttcaaacacg tgcaggctgt ttaatagggg ctgaacatgt caacaactca 23520 tatgagtgtg acatacccat tggtgcaggt atatgcgcta gttatcagac tcagactaat 23580 tctcatcggc gggcacgtag tgtagctagt caatccatca ttgcctacac tatgtcactt 23640 ggtgcagaaa attcagttgc ttactctaat aactctattg ccatacccat aaattttact 23700 attagtgtta ccacagaaat tctaccagtg tctatgacca agacatcagt agattgtaca 23760 atgtacattt gtggtgattc aactgaatgc agcaatcttt tgttgcaata tggcagtttt 23820 tgtacacaat taaaccgtgc tttaactgga atagctgttg aacaagacaa aaacacccaa 23880 gaagtttttg cacaagtcaa acaaatttac aaaacaccac caattaaaga ttttggtggt 23940 tttaattttt cacaaatatt accagatcca tcaaaaccaa gcaagaggtc atttattgaa 24000 gatctacttt tcaacaaagt gacacttgca gatgctggct tcatcaaaca atatggtgat 24060 tgccttggtg atattgctgc tagagacctc atttgtgcac aaaagtttaa cggccttact 24120 gttttgccac ctttgctcac agatgaaatg attgctcaat acacttctgc actgttagcg 24180 ggtacaatca cttctggttg gacctttggt gcaggtgctg cattacaaat accatttgct 24240 atgcaaatgg cttataggtt taatggtatt ggagttacac agaatgttct ctatgagaac 24300 caaaaattga ttgccaacca atttaatagt gctattggca aaattcaaga ctcactttct 24360 tccacagcaa gtgcacttgg aaaacttcaa gatgtggtca accaaaatgc acaagcttta 24420 aacacgcttg ttaaacaact tagctccaat tttggtgcaa tttcaagtgt tttaaatgat 24480 atccttgcac gtcttgacaa agttgaggct gaagtgcaaa ttgataggtt gatcacaggc 24540 agacttcaaa gtttgcagac atatgtgact caacaattaa ttagagctgc agaaatcaga 24600 gcttctgcta atcttgctgc tactaaaatg tcagagtgtg tacttggaca atcaaaaaga 24660 gttgattttt gtggaaaggg ctatcatctt atgtccttcc ctcagtcagc acctcatggt 24720 gtagtcttct tgcatgtgac ttatgtccct gcacaagaaa agaacttcac aactgctcct 24780 gccatttgtc atgatggaaa agcacacttt cctcgtgaag gtgtctttgt ttcaaatggc 24840 acacactggt ttgtaacaca aaggaatttt tatgaaccac aaatcattac tacacacaac 24900 acatttgtgt ctggtaactg tgatgttgta ataggaattg tcaacaacac agtttatgat 24960 cctttgcaac ctgaattaga ctcattcaag gaggagttag ataaatattt taagaatcat 25020 acatcaccag atgttgattt aggtgacatc tctggcatta atgcttcagt tgtaaacatt 25080 caaaaagaaa ttgaccgcct caatgaggtt gccaagaatt taaatgaatc tctcatcgat 25140 ctccaagaac ttggaaagta tgagcagtat ataaaatggc catggtacat ttggctaggt 25200 tttatagctg gcttgattgc catagtaatg gtgacaatta tgctttgctg tatgaccagt 25260 tgctgtagtt gtctcaaggg ctgttgttct tgtggatcct gctgcaaatt tgatgaagac 25320 gactctgagc cagtgctcaa aggagtcaaa ttacattaca cataaacgaa cttatggatt 25380 tgtttatgag aatcttcaca attggaactg taactttgaa gcaaggtgaa atcaaggatg 25440 ctactccttc agattttgtt cgcgctactg caacgatacc gatacaagcc tcactccctt 25500 tcggatggct tattgttggc gttgcacttc ttgctgtttt tcagagcgct tccaaaatca 25560 taaccctcaa aaagagatgg caactagcac tctccaaggg tgttcacttt gtttgcaact 25620 tgctgttgtt gtttgtaaca gtttactcac accttttgct cgttgctgct ggccttgaag 25680 ccccttttct ctatctttat gctttagtct acttcttgca gagtataaac tttgtaagaa 25740 taataatgag gctttggctt tgctggaaat gccgttccaa aaacccatta ctttatgatg 25800 ccaactattt tctttgctgg catactaatt gttacgacta ttgtatacct tacaatagtg 25860 taacttcttc aattgtcatt acttcaggtg atggcacaac aagtcctatt tctgaacatg 25920 actaccagat tggtggttat actgaaaaat gggaatctgg agtaaaagac tgtgttgtat 25980 tacacagtta cttcacttca gactattacc agctgtactc aactcaattg agtacagaca 26040 ctggtgttga acatgttacc ttcttcatct acaataaaat tgttgatgag cctgaagaac 26100 atgtccaaat tcacacaatc gacggttcat ccggagttgt taatccagta atggaaccaa 26160 tttatgatga accgacgacg actactagcg tgcctttgta agcacaagct gatgagtacg 26220 aacttatgta ctcattcgtt tcggaagaga caggtacgtt aatagttaat agcgtacttc 26280 tttttcttgc tttcgtggta ttcttgctag ttacactagc catccttact gcgcttcgat 26340 tgtgtgcgta ctgctgcaat attgttaacg tgagtcttgt aaaaccttct ttttacgttt 26400 actctcgtgt taaaaatctg aattcttcta gagttcctga tcttctggtc taaacgaact 26460 aaatattata ttagtttttc tgtttggaac tttaatttta gccatggcag attccaacgg 26520 tactattacc gttgaagagc ttaaaaagct ccttgaacaa tggaacctag taataggttt 26580 cctattcctt acatggattt gtcttctaca atttgcctat gccaacagga ataggttttt 26640 gtatataatt aagttaattt tcctctggct gttatggcca gtaactttag cttgttttgt 26700 gcttgctgct gtttacagaa taaattggat caccggtgga attgctatcg caatggcttg 26760 tcttgtaggc ttgatgtggc tcagctactt cattgcttct ttcagactgt ttgcgcgtac 26820 gcgttccatg tggtcattca atccagaaac taacattctt ctcaacgtgc cactccatgg 26880 cactattctg accagaccgc ttctagaaag tgaactcgta atcggagctg tgatccttcg 26940 tggacatctt cgtattgctg gacaccatct aggacgctgt gacatcaagg acctgcctaa 27000 agaaatcact gttgctacat cacgaacgct ttcttattac aaattgggag cttcgcagcg 27060 tgtagcaggt gactcaggtt ttgctgcata cagtcgctac aggattggca actataaatt 27120 aaacacagac cattccagta gcagtgacaa tattgctttg cttgtacagt aagtgacaac 27180 agatgtttca tctcgttgac tttcaggtta ctatagcaga gatattacta attattatga 27240 ggacttttaa agtttccatt tggaatcttg attacatcat aaacctcata attaaaaatt 27300 tatctaagtc actaactgag aataaatatt ctcaattaga tgaagagcaa ccaatggaga 27360 ttgattaaac gaacatgaaa attattcttt tcttggcact gataacactc gctacttgtg 27420 agctttatca ctaccaagag tgtgttagag gtacaacagt acttttaaaa gaaccttgct 27480 cttctggaac atacgagggc aattcaccat ttcatcctct agctgataac aaatttgcac 27540 tgacttgctt tagcactcaa tttgcttttg cttgtcctga cggcgtaaaa cacgtctatc 27600 agttacgtgc cagatcagtt tcacctaaac tgttcatcag acaagaggaa gttcaagaac 27660 tttactctcc aatttttctt attgttgcgg caatagtgtt tataacactt tgcttcacac 27720 tcaaaagaaa gacagaatga ttgaactttc attaattgac ttctatttgt gctttttagc 27780 ctttctgcta ttccttgttt taattatgct tattatcttt tggttctcac ttgaactgca 27840 agatcataat gaaacttgtc acgcctaaac gaacatgaaa tttcttgttt tcttaggaat 27900 catcacaact gtagctgcat ttcaccaaga atgtagttta cagtcatgta cttaacatca 27960 accatatgta gttgatgacc cgtgtcctat tcacttctat tctaaatggt atattagagt 28020 aggagctata aaatcagcac ctttaattga attgtgcgtg gatgaggctg gttctaaatc 28080 acccattcag tgcatcgata tcggtaatta tacagtttcc tgtttacctt ttacaattaa 28140 ttgccaggaa cctaaattgg gtagtcttgt agtgcgttgt tcgttctatg aagacttttt 28200 agagtatcat gacgttcgtg ttgttttaga tttcatctaa acgaacaaac taaatgtctc 28260 taaatggacc ccaaaatcag cgaaatgcac cccgcattac gtttggtgga ccctcagatt 28320 caactggcag taaccagaat ggagaacgca gtggggcgcg atcaaaacaa cgtcggcccc 28380 aaggtttacc caataatact gcgtcttggt tcaccgctct cactcaacat ggcaaggaag 28440 accttaaatt ccctcgagga caaggcgttc caattaacac caatagcagt ccagatgacc 28500 aaattggcta ctaccgaaga gctaccagac gaattcgtgg tggtgacggt aaaatgaaag 28560 atctcagtcc aagatggtat ttctactacc taggaactgg gccagaagct ggacttccct 28620 atggtgctaa caaagacggc atcatatggg ttgcaactga gggagccttg aatacaccaa 28680 aagatcacat tggcacccgc aatcctgcta acaatgctgc aatcgtgcta caacttcctc 28740 aaggaacaac attgccaaaa ggcttctacg cagaagggag cagaggcggc agtcaagcct 28800 cttctcgttc ctcatcacgt agtcgcaaca gttcaagaaa ttcaactcca ggcagcagta 28860 aacgaacttc tcctgctaga atggctggca atggcggtga tgctgctctt gctttgctgc 28920 tgcttgacag attgaaccag cttgagagca aaatgtttgg taaaggccaa caacaacaag 28980 gccaaactgt cactaagaaa tctgctgctg aggcttctaa gaagcctcgg caaaaacgta 29040 ctgccactaa agcatacaat gtaacacaag ctttcggcag acgtggtcca gaacaaaccc 29100 aaggaaattt tggggaccag gaactaatca gacaaggaac tgattacaaa cattggccgc 29160 aaattgcaca atttgccccc agcgcttcag cgttcttcgg aatgtcgcgc attggcatgg 29220 aagtcacacc ttcgggaacg tggttgacct acacaggtgc catcaaattg gatgacaaag 29280 atccaaattt caaagatcaa gtcattttgc tgaataagca tattgacgca tacaaaacat 29340 tcccaccaac agagcctaaa aaggacaaaa agaagaaggc tgatgaaact caagccttac 29400 cgcagagaca gaagaaacag caaactgtga ctcttcttcc tgctgcagat ttggatgatt 29460 tctccaaaca attgcaacaa tccatgagca gtgctgactc aactcaggcc taaactcatg 29520 cagaccacac aaggcagatg ggctatataa acgttttcgc ttttccgttt acgatatata 29580 gtctactctt gtgcagaatg aattctcgta actacatagc acaagtagat gtagttaact 29640 ttaatctcac atagcaatct ttaatcagtg tgtaacatta gggaggactt gaaagagcca 29700 ccacattttc accgaggcca cgcggagtac gatcgagtgt acagtgaaca atgctaggga 29760 gagctgccta tatggaagag ccctaatgtg taaaattaat tttagtagtg ctatccccat 29820 gtgattttaa tagcttctta ggagaatgnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 29880 nnn 29883 <210> 23 <211> 1270 <212> PRT <213> SARS-CoV2 <400> 23 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ser Gln Cys Val 1 5 10 15 Asn Leu Thr Thr Arg Thr Gln Leu Pro Pro Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Ser Gly Thr Asn Gly Thr Lys Arg Phe Asp Asn Pro 65 70 75 80 Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu Lys Ser 85 90 95 Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser Lys Thr 100 105 110 Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile Lys Val 115 120 125 Cys Glu Phe Gln Phe Cys Asn Asp Pro Phe Leu Gly Val Tyr Hes Lys 130 135 140 Asn Asn Lys Ser Trp Met Glu Ser Glu Phe Arg Val Tyr Ser Ser Ala 145 150 155 160 Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu Met Asp Leu 165 170 175 Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Arg Glu Phe Val Phe Lys 180 185 190 Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr Pro Ile Asn 195 200 205 Leu Val Arg Asp Leu Pro Gln Gly Phe Ser Ala Leu Glu Pro Leu Val 210 215 220 Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Thr Leu Leu Ala 225 230 235 240 Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser Gly Trp Thr 245 250 255 Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro Arg Thr Phe 260 265 270 Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala Val Asp Cys 275 280 285 Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys Ser Phe Thr 290 295 300 Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Val Gln Pro Thr 305 310 315 320 Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys Pro Phe Gly 325 330 335 Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala Trp Asn Arg 340 345 350 Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Val Leu Tyr Asn Ser 355 360 365 Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro Thr Lys Leu 370 375 380 Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe Val Ile Arg 385 390 395 400 Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly Lys Ile Ala 405 410 415 Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys Val Ile Ala 420 425 430 Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn Tyr Asn Tyr 435 440 445 Leu Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe Glu Arg Asp 450 455 460 Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys Asn Gly Val 465 470 475 480 Glu Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly Phe Gln Pro 485 490 495 Thr Tyr Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val Leu Ser Phe 500 505 510 Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys Lys Ser Thr 515 520 525 Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn Gly Leu Thr 530 535 540 Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu Pro Phe Gln 545 550 555 560 Gln Phe Gly Arg Asp Ile Asp Asp Thr Thr Asp Ala Val Arg Asp Pro 565 570 575 Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe Gly Gly Val 580 585 590 Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val Ala Val Leu 595 600 605 Tyr Gln Gly Val Asn Cys Thr Glu Val Pro Val Ala Ile Hes Ala Asp 610 615 620 Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser Asn Val Phe 625 630 635 640 Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Hes Val Asn Asn Ser 645 650 655 Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala Ser Tyr Gln 660 665 670 Thr Gln Thr Asn Ser Hes Arg Arg Ala Arg Ser Val Ala Ser Gln Ser 675 680 685 Ile Ile Ala Tyr Thr Met Ser Leu Gly Ala Glu Asn Ser Val Ala Tyr 690 695 700 Ser Asn Asn Ser Ile Ala Ile Pro Ile Asn Phe Thr Ile Ser Val Thr 705 710 715 720 Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val Asp Cys Thr 725 730 735 Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu Leu Leu Gln 740 745 750 Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr Gly Ile Ala 755 760 765 Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln Val Lys Gln 770 775 780 Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe Asn Phe Ser 785 790 795 800 Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser Phe Ile Glu 805 810 815 Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly Phe Ile Lys 820 825 830 Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp Leu Ile Cys 835 840 845 Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu Leu Thr Asp 850 855 860 Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly Thr Ile Thr 865 870 875 880 Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile Pro Phe Ala 885 890 895 Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr Gln Asn Val 900 905 910 Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn Ser Ala Ile 915 920 925 Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala Leu Gly Lys 930 935 940 Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn Thr Leu Val 945 950 955 960 Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val Leu Asn Asp 965 970 975 Ile Leu Ala Arg Leu Asp Lys Val Glu Ala Glu Val Gln Ile Asp Arg 980 985 990 Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val Thr Gln Gln 995 1000 1005 Leu Ile Arg Ala Ala Glu Ile Arg Ala Ser Ala Asn Leu Ala Ala 1010 1015 1020 Thr Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys Arg Val Asp 1025 1030 1035 Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro Gln Ser Ala 1040 1045 1050 Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val Pro Ala Gln 1055 1060 1065 Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes Asp Gly Lys 1070 1075 1080 Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn Gly Thr Hes 1085 1090 1095 Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln Ile Ile Thr 1100 1105 1110 Thr Hes Asn Thr Phe Val Ser Gly Asn Cys Asp Val Val Ile Gly 1115 1120 1125 Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro Glu Leu Asp 1130 1135 1140 Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn Hes Thr Ser 1145 1150 1155 Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn Ala Ser Val 1160 1165 1170 Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu Val Ala Lys 1175 1180 1185 Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu Gly Lys Tyr 1190 1195 1200 Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu Gly Phe Ile 1205 1210 1215 Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met Leu Cys Cys 1220 1225 1230 Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys Ser Cys Gly 1235 1240 1245 Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro Val Leu Lys 1250 1255 1260 Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 24 <211> 29832 <212> ADN <213> SARS-CoV2 <400> 24 aaggtttata ccttcccagg taacaaacca accaactttc gatctcttgt agatctgttc 60 tctaaacgaa ctttaaaatc tgtgtggctg tcactcggct gcatgcttag tgcactcacg 120 cagtataatt aataactaat tactgtcgtt gacaggacac gagtaactcg tctatcttct 180 gcaggctgct tacggtttcg tccgtgttgc agccgatcat cagcacatct aggttttgtc 240 cgggtgtgac cgaaaggtaa gatggagagc cttgtccctg gtttcaacga gaaaacacac 300 gtccaactca gtttgcctgt tttacaggtt cgcgacgtgc tcgtacgtgg ctttggagac 360 tccgtggagg aggtcttatc agaggcacgt caacatctta aagatggcac ttgtggctta 420 gtagaagttg aaaaaggcgt tttgcctcaa cttgaacagc cctatgtgtt catcaaacgt 480 tcggatgctc gaactgcacc tcatggtcat gttatggttg agctggtagc agaactcgaa 540 ggcattcagt acggtcgtag tggtgagaca cttggtgtcc ttgtccctca tgtgggcgaa 600 ataccagtgg cttaccgcaa ggttcttctt cgtaagaacg gtaataaagg agctggtggc 660 catagttacg gcgccgatct aaagtcattt gacttaggcg acgagcttgg cactgatcct 720 tatgaagatt ttcaagaaaa ctggaacact aaacatagca gtggtgttac ccgtgaactc 780 atgcgtgagc ttaacggagg ggcatacact cgctatgtcg ataacaactt ctgtggccct 840 gatggctacc ctcttgagtg cattaaagac cttctagcac gtgctggtaa agcttcatgc 900 actttgtccg aacaactgga ctttattgac actaagaggg gtgtatactg ctgccgtgaa 960 catgagcatg aaattgcttg gtacacggaa cgttctgaaa agagctatga attgcagaca 1020 ccttttgaaa ttaaattggc aaagaaattt gacatcttca atggggaatg tccaaatttt 1080 gtatttccct taaattccat aatcaagact attcaaccaa gggttgaaaa gaaaaagctt 1140 gatggcttta tgggtagaat tcgatctgtc tatccagttg cgtcaccaaa tgaatgcaac 1200 caaatgtgcc tttcaactct catgaagtgt gatcattgtg gtgaaacttc atggcagacg 1260 ggcgattttg ttaaagccac ttgcgaattt tgtggcactg agaatttgac taaagaaggt 1320 gccactactt gtggttactt accccaaaat gctgttgtta aaatttattg tccagcatgt 1380 cacaattcag aagtaggacc tgagcatagt cttgccgaat accataatga atctggcttg 1440 aaaaccattc ttcgtaaggg tggtcgcact attgcctttg gaggctgtgt gttctcttat 1500 gttggttgcc ataacaagtg tgcctattgg gttccacgtg ctagcgctaa cataggttgt 1560 aaccatacag gtgttgttgg agaaggttcc gaaggtctta atgacaacct tcttgaaata 1620 ctccaaaaag agaaagtcaa catcaatatt gttggtgact ttaaacttaa tgaagagatc 1680 gccattattt tggcatcttt ttctgcttcc acaagtgctt ttgtggaaac tgtgaaaggt 1740 ttggattata aagcattcaa acaaattgtt gaatcctgtg gtaattttaa agttacaaaa 1800 ggaaaagcta aaaaaggtgc ctggaatatt ggtgaacaga aatcaatact gagtcctctt 1860 tatgcatttg catcagaggc tgctcgtgtt gtacgatcaa ttttctcccg cactcttgaa 1920 actgctcaaa attctgtgcg tgttttacag aaggccgcta taacaatact agatggaatt 1980 tcacagtatt cactgagact cattgatgct atgatgttca catctgattt ggctactaac 2040 aatctagttg taatggccta cattacaggt ggtgttgttc agttgacttc gcagtggcta 2100 actaacatct ttggcactgt ttatgaaaaa ctcaaacccg tccttgattg gcttgaagag 2160 aagtttaagg aaggtgtaga gtttcttaga gacggttggg aaattgttaa atttatctca 2220 acctgtgctt gtgaaattgt cggtggacaa attgtcacct gtgcaaagga aattaaggag 2280 agtgttcaga cattctttaa gcttgtaaat aaatttttgg ctttgtgtgc tgactctatc 2340 attattggtg gagctaaact taaagccttg aatttaggtg aaacatttgt cacgcactca 2400 aagggattgt acagaaagtg tgttaaatcc agagaagaaa ctggcctact catgcctcta 2460 aaagccccaa aagaaattat cttcttagag ggagaaacac ttcccacaga agtgttaaca 2520 gaggaagttg tcttgaaaac tggtgattta caaccattag aacaacctac tagtgaagct 2580 gttgaagctc cattggttgg tacaccagtt tgtattaacg ggcttatgtt gctcgaaatc 2640 aaagacacag aaaagtactg tgcccttgca cctaatatga tggtaacaaa caataccttc 2700 acactcaaag gcggtgcacc aacaaaggtt acttttggtg atgacactgt gatagaagtg 2760 caaggttaca agagtgtgaa tatcactttt gaacttgatg aaaggattga taaagtactt 2820 aatgagaagt gctctgccta tacagttgaa ctcggtacag aagtaaatga gttcgcctgt 2880 gttgtggcag atgctgtcat aaaaactttg caaccagtat ctgaattact tacaccactg 2940 ggcattgatt tagatgagtg gagtatggct acatactact tatttgatga gtctggtgag 3000 tttaaattgg cttcacatat gtattgttct ttttaccctc cagatgagga tgaagaagaa 3060 ggtgattgtg aagaagaaga gtttgagcca tcaactcaat atgagtatgg tactgaagat 3120 gattaccaag gtaaaccttt ggaatttggt gccacttctg ctgctcttca acctgaagaa 3180 gagcaagaag aagattggtt agatgatgat agtcaacaaa ctgttggtca acaagacggc 3240 agtgaggaca atcagacaac tactattcaa acaattgttg aggttcaacc tcaattagag 3300 atggaactta caccagttgt tcagactatt gaagtgaata gttttagtgg ttatttaaaa 3360 cttactgaca atgtatacat taaaaatgca gacattgtgg aagaagctaa aaaggtaaaa 3420 ccaacagtgg ttgttaatgc agccaatgtt taccttaaac atggaggagg tgttgcagga 3480 gccttaaata aggctactaa caatgccatg caagttgaat ctgatgatta catagctact 3540 aatggaccac ttaaagtggg tggtagttgt gttttaagcg gacacaatct tgctaaacac 3600 tgtcttcatg ttgtcggccc aaatgttaac aaaggtgaag acattcaact tcttaagagt 3660 gcttatgaaa attttaatca gcacgaagtt ctacttgcac cattattatc agctggtatt 3720 tttggtgctg accctataca ttctttaaga gtttgtgtag atactgttcg cacaaatgtc 3780 tacttagctg tctttgataa aaatctctat gacaaacttg tttcaagctt tttggaaatg 3840 aagagtgaaa agcaagttga acaaaagatc gctgagattc ctaaagagga agttaagcca 3900 tttataactg aaagtaaacc ttcagttgaa cagagaaaac aagatgataa gaaaatcaaa 3960 gcttgtgttg aagaagttac aacaactctg gaagaaacta agttcctcac agaaaacttg 4020 ttactttata ttgacattaa tggcaatctt catccagatt ctgccactct tgttagtgac 4080 attgacatca ctttcttaaa gaaagatgct ccatatatag tgggtgatgt tgttcaagag 4140 ggtgttttaa ctgctgtggt tatacctact aaaaaggctg gtggcactac tgaaatgcta 4200 gcgaaagctt tgagaaaagt gccaacagac aattatataa ccacttaccc gggtcagggt 4260 ttaaatggtt acactgtaga ggaggcaaag acagtgctta aaaagtgtaa aagtgccttt 4320 tacattctac catctattat ctctaatgag aagcaagaaa ttcttggaac tgtttcttgg 4380 aatttgcgag aaatgcttgc acatgcagaa gaaacacgca aattaatgcc tgtctgtgtg 4440 gaaactaaag ccatagtttc aactatacag cgtaaatata agggtattaa aatacaagag 4500 ggtgtggttg attatggtgc tagattttac ttttacacca gtaaaacaac tgtagcgtca 4560 cttatcaaca cacttaacga tctaaatgaa actcttgtta caatgccact tggctatgta 4620 acacatggct taaatttgga agaagctgct cggtatatga gatctctcaa agtgccagct 4680 acagtttctg tttcttcacc tgatgctgtt acagcgtata atggttatct tacttcttct 4740 tctaaaacac ctgaagaaca ttttattgaa accatctcac ttgctggttc ctataaagat 4800 tggtcctatt ctggacaatc tacacaacta ggtatagaat ttcttaagag aggtgataaa 4860 agtgtatatt acactagtaa tcctaccaca ttccacctag atggtgaagt tatcaccttt 4920 gacaatctta agacacttct ttctttgaga gaagtgagga ctattaaggt gtttacaaca 4980 gtagacaaca ttaacctcca cacgcaagtt gtggacatgt caatgacata tggacaacag 5040 tttggtccaa cttatttgga tggagctgat gttactaaaa taaaacctca taattcacat 5100 gaaggtaaaa cattttatgt tttacctaat gatgacactc tacgtgttga ggcttttgag 5160 tactaccaca caactgatcc tagttttctg ggtaggtaca tgtcagcatt aaatcacact 5220 aaaaagtgga aatacccaca agttaatggt ttaacttcta ttaaatgggc agataacaac 5280 tgttatcttg ccactgcatt gttaacactc caacaaatag agttgaagtt taatccacct 5340 gctctacaag atgcttatta cagagcaagg gctggtgaag ctgctaactt ttgtgcactt 5400 atcttagcct actgtaataa gacagtaggt gagttaggtg atgttagaga aacaatgagt 5460 tacttgtttc aacatgccaa tttagattct tgcaaaagag tcttgaacgt ggtgtgtaaa 5520 acttgtggac aacagcagac aacccttaag ggtgtagaag ctgttatgta catgggcaca 5580 ctttcttatg aacaatttaa gaaaggtgtt cagatacctt gtacgtgtgg taaacaagct 5640 acaaaatatc tagtacaaca ggagtcacct tttgttatga tgtcagcacc acctgctcag 5700 tatgaactta agcatggtac atttacttgt gctagtgagt acactggtaa ttaccagtgt 5760 ggtcactata aacatataac ttctaaagaa actttgtatt gcatagacgg tgctttactt 5820 acaaagtcct cagaatacaa aggtcctatt acggatgttt tctacaaaga aaacagttac 5880 acaacaacca taaaaccagt tacttataaa ttggatggtg ttgtttgtac agaaattgac 5940 cctaagttgg acaattatta taagaaagac aattcttatt tcacagagca accaattgat 6000 cttgtaccaa accaaccata tccaaacgca agcttcgata attttaagtt tgtatgtgat 6060 aatatcaaat ttgctgatga tttaaaccag ttaactggtt ataagaaacc tgcttcaaga 6120 gagcttaaag ttacattttt ccctgactta aatggtgatg tggtggctat tgattataaa 6180 cactacacac cctcttttaa gaaaggagct aaattgttac ataaacctat tgtttggcat 6240 gttaacaatg caactaataa agccacgtat aaaccaaata cctggtgtat acgttgtctt 6300 tggagcacaa aaccagttga aacatcaaat tcgtttgatg tactgaagtc agaggacgcg 6360 cagggaatgg ataatcttgt ctgcgaagat ctaaaaccag tctctgaaga agtagtggaa 6420 aatcctacca tacagaaaga cgttcttgag tgtaatgtga aaactaccga agttgtagga 6480 gacattatac ttaaaccagc aaataatagt ttaaaaatta cagaagaggt tggccacaca 6540 gatctaatgg ctgcttatgt agacaattct agtcttacta ttaagaaacc taatgaatta 6600 tctagagtat taggtttgaa aacccttgct actcatggtt tagctgctgt taatagtgtc 6660 ccttgggata ctatagctaa ttatgctaag ccttttctta acaaagttgt tagtacaact 6720 actaacatag ttacacggtg tttaaaccgt gtttgtacta attatatgcc ttatttcttt 6780 actttattgc tacaattgtg tacttttact agaagtacaa attctagaat taaagcatct 6840 atgccgacta ctatagcaaa gaatactgtt aagagtgtcg gtaaattttg tctagaggct 6900 tcatttaatt atttgaagtc acctaatttt tctaaactga taaatattat aatttggttt 6960 ttactattaa gtgtttgcct aggttcttta atctactcaa ccgctgcttt aggtgtttta 7020 atgtctaatt taggcatgcc ttcttactgt actggttaca gagaaggcta tttgaactct 7080 actaatgtca ctattgcaac ctactgtact ggttctatac cttgtagtgt ttgtcttagt 7140 ggtttagatt ctttagacac ctatccttct ttagaaacta tacaaattac catttcatct 7200 tttaaatggg atttaactgc ttttggctta gttgcagagt ggtttttggc atatattctt 7260 ttcactaggt ttttctatgt acttggattg gctgcaatca tgcaattgtt tttcagctat 7320 tttgcagtac attttattag taattcttgg cttatgtggt taataattaa tcttgtacaa 7380 atggccccga tttcagctat ggttagaatg tacatcttct ttgcatcatt ttattatgta 7440 tggaaaagtt atgtgcatgt tgtagacggt tgtaattcat caacttgtat gatgtgttac 7500 aaacgtaata gagcaacaag agtcgaatgt acaactattg ttaatggtgt tagaaggtcc 7560 ttttatgtct atgctaatgg aggtaaaggc ttttgcaaac tacacaattg gaattgtgtt 7620 aattgtgata cattctgtgc tggtagtaca tttattagtg atgaagttgc gagagacttg 7680 tcactacagt ttaaaagacc aataaatcct actgaccagt cttcttacat cgttgatagt 7740 gttacagtga agaatggttc catccatctt tactttgata aagctggtca aaagacttat 7800 gaaagacatt ctctctctca ttttgttaac ttagacaacc tgagagctaa taacactaaa 7860 ggttcattgc ctattaatgt tatagttttt gatggtaaat caaaatgtga agaatcatct 7920 gcaaaatcag cgtctgttta ctacagtcag cttatgtgtc aacctatact gttactagat 7980 caggcattag tgtctgatgt tggtgatagt gcggaagttg cagttaaaat gtttgatgct 8040 tacgttaata cgttttcatc aacttttaac gtaccaatgg aaaaactcaa aacactagtt 8100 gcaactgcag aagctgaact tgcaaagaat gtgtccttag acaatgtctt atctactttt 8160 atttcagcag ctcggcaagg gtttgttgat tcagatgtag aaactaaaga tgttgttgaa 8220 tgtcttaaat tgtcacatca atctgacata gaagttactg gcgatagttg taataactat 8280 atgctcacct ataacaaagt tgaaaacatg acaccccgtg accttggtgc ttgtattgac 8340 tgtagtgcgc gtcatattaa tgcgcaggta gcaaaaagtc acaacattgc tttgatatgg 8400 aacgttaaag atttcatgtc attgtctgaa caactacgaa aacaaatacg tagtgctgct 8460 aaaaagaata acttaccttt taagttgaca tgtgcaacta ctagacaagt tgttaatgtt 8520 gtaacaacaa agatagcact taagggtggt aaaattgtta ataattggtt gaagcagtta 8580 attaaagtta cacttgtgtt cctttttgtt gctgctattt tctatttaat aacacctgtt 8640 catgtcatgt ctaaacatac tgacttttca agtgaaatca taggatacaa ggctattgat 8700 ggtggtgtca ctcgtgacat agcatctaca gatacttgtt ttgctaacaa acatgctgat 8760 tttgacacat ggtttagcca gcgtggtggt agttatacta atgacaaagc ttgcccattg 8820 attgctgcag tcataacaag agaagtgggt tttgtcgtgc ctggtttgcc tggcacgata 8880 ttacgcacaa ctaatggtga ctttttgcat ttcttaccta gagtttttag tgcagttggt 8940 aacatctgtt acacaccatc aaaacttata gagtacactg actttgcaac atcagcttgt 9000 gttttggctg ctgaatgtac aatttttaaa gatgcttctg gtaagccagt accatattgt 9060 tatgatacca atgtactaga aggttctgtt gcttatgaaa gtttacgccc tgacacacgt 9120 tatgtgctca tggatggctc tattattcaa tttcctaaca cctaccttga aggttctgtt 9180 agagtggtaa caacttttga ttctgagtac tgtaggcacg gcacttgtga aagatcagaa 9240 gctggtgttt gtgtatctac tagtggtaga tgggtactta acaatgatta ttacagatct 9300 ttaccaggag ttttctgtgg tgtagatgct gtaaatttac ttactaatat gtttacacca 9360 ctaattcaac ctattggtgc tttggacata tcagcatcta tagtagctgg tggtattgta 9420 gctatcgtag taacatgcct tgcctactat tttatgaggt ttagaagagc ttttggtgaa 9480 tacagtcatg tagttgcctt taatacttta ctattcctta tgtcattcac tgtactctgt 9540 ttaacaccag tttactcatt cttacctggt gtttattctg ttatttactt gtacttgaca 9600 ttttatctta ctaatgatgt ttctttttta gcacatattc agtggatggt tatgttcaca 9660 cctttagtac ctttctggat aacaattgct tatatcattt gtatttccac aaagcatttc 9720 tattggttct ttactaatta cctaaagaga cgtgtagtct ttaatggtgt ttcctttagt 9780 acttttgaag aagctgcgct gtgcaccttt ttgttaaata aagaaatgta tctaaagttg 9840 cgtagtgatg tgctattacc tcttacgcaa tataatagat acttagctct ttataataag 9900 tacaagtatt ttagtggagc aatggataca actagctaca gagaagctgc ttgttgtcat 9960 ctcgcaaagg ctctcaatga cttcagtaac tcaggttctg atgttcttta ccaaccacca 10020 caaacctcta tcacctcagc tgttttgcag agtggtttta gaaaaatggc attcccatct 10080 ggtaaagttg agggttgtat ggtacaagta acttgtggta caactacact taacggtctt 10140 tggcttgatg acgtagttta ctgtccaaga catgtgatct gcacctctga agacatgctt 10200 aaccctaatt atgaagattt actcattcgt aagtctaatc ataatttctt ggtacaggct 10260 ggtaatgttc aactcagggt tattggacat tctatgcaaa attgtgtact taagcttaag 10320 gttgatacag ccaatcctaa gacacctaag tataagtttg ttcgcattca accaggacag 10380 actttttcag tgttagcttg ttacaatggt tcaccatctg gtgtttacca atgtgctatg 10440 aggcccaatt tcactattaa gggttcattc cttaatggtt catgtggtag tgttggtttt 10500 aacatagatt atgactgtgt ctctttttgt tacatgcacc atatggaatt accaactgga 10560 gttcatgctg gcacagactt agaaggtaac ttttatggac cttttgttga caggcaaaca 10620 gcacaagcag ctggtacgga cacaactatt acagttaatg ttttagcttg gttgtacgct 10680 gctgttataa atggagacag gtggtttctc aatcgattta ccacaactct taatgacttt 10740 aaccttgtgg ctatgaagta caattatgaa cctctaacac aagaccatgt tgacatacta 10800 ggacctcttt ctgctcaaac tggaattgcc gttttagata tgtgtgcttc attaaaagaa 10860 ttactgcaaa atggtatgaa tggacgtacc atattgggta gtgctttatt agaagatgaa 10920 tttacacctt ttgatgttgt tagacaatgc tcaggtgtta ctttccaaag tgcagtgaaa 10980 agaacaatca agggtacaca ccactggttg ttactcacaa ttttgacttc acttttagtt 11040 ttagtccaga gtactcaatg gtctttgttc ttttttttgt atgaaaatgc ctttttacct 11100 tttgctatgg gtattattgc tatgtctgct tttgcaatga tgtttgtcaa acataagcat 11160 gcatttctct gtttgttttt gttaccttct cttgccactg tagcttattt taatatggtc 11220 tatatgcctg ctagttgggt gatgcgtatt atgacatggt tggatatggt tgatactagt 11280 ttgtctggtt ttaagctaaa agactgtgtt atgtatgcat cagctgtagt gttactaatc 11340 cttatgacag caagaactgt gtatgatgat ggtgctagga gagtgtggac acttatgaat 11400 gtcttgacac tcgtttataa agtttattat ggtaatgctt tagatcaagc catttccatg 11460 tgggctctta taatctctgt tacttctaac tactcaggtg tagttacaac tgtcatgttt 11520 ttggccaaag gtattgtttt tatgtgtgtt gagtattgcc ctattttctt cataactggt 11580 aatacacttc agtgtataat gctagtttat tgtttcttag gctatttttg tacttgttac 11640 tttggcctct tttgtttact caaccgctac tttagactga ctcttggtgt ttatgattac 11700 ttagtttcta cacaggagtt tagatatatg aattcacagg gactactccc acccaagaat 11760 agcatagatg ccttcaaact caacattaaa ttgttgggtg ttggtggcaa accttgtatc 11820 aaagtagcca ctgtacagtc taaaatgtca gatgtaaagt gcacatcagt agtcttactc 11880 tcagttttgc aacaactcag agtagaatca tcatctaaat tgtgggctca atgtgtccag 11940 ttacacaatg acattctctt agctaaagat actactgaag cctttgaaaa aatggtttca 12000 ctactttctg ttttgctttc catgcagggt gctgtagaca taaacaagct ttgtgaagaa 12060 atgctggaca acagggcaac cttacaagct atagcctcag agtttagttc ccttccatca 12120 tatgcagctt ttgctactgc tcaagaagct tatgagcagg ctgttgctaa tggtgattct 12180 gaagttgttc ttaaaaagtt gaagaagtct ttgaatgtgg ctaaatctga atttgaccgt 12240 gatgcagcca tgcaacgtaa gttggaaaag atggctgatc aagctatgac ccaaatgtat 12300 aaacaggcta gatctgagga caagagggca aaagttacta gtgctatgca gacaatgctt 12360 ttcactatgc ttagaaagtt ggataatgat gcactcaaca acattatcaa caatgcaaga 12420 gatggttgtg ttcccttgaa cataatacct cttacaacag cagccaaatt aatggttgtc 12480 ataccagact ataacacata taaaaatacg tgtgatggta caacatttac ttatgcatca 12540 gcattgtggg aaatccaaca ggttgtagat gcagatagta aaattgttca acttagtgaa 12600 attagtatgg acaattcacc taatttagca tggcctctta ttgtaacagc tttaagggcc 12660 aattctgctg tcaaattaca gaataatgag cttagtcctg ttgcactacg acagatgtct 12720 tgtgctgccg gtactacaca aactgcttgc actgatgaca atgcgttagc ttactacaac 12780 acaacaaagg gaggtaggtt tgtacttgca ctgttatccg atttacagga tttgaaatgg 12840 gctagattcc ctaagagtga tggaactggt actatctata cagaactgga accaccttgt 12900 aggtttgtta cagacacacc taaaggtcct aaagtgaagt atttatactt tattaaagga 12960 ttaaacaacc taaatagagg tatggtactt ggtagtttag ctgccacagt acgtctacaa 13020 gctggtaatg caacagaagt gcctgccaat tcaactgtat tatctttctg tgcttttgct 13080 gtagatgctg ctaaagctta caaagattat ctagctagtg ggggacaacc aatcactaat 13140 tgtgttaaga tgttgtgtac acacactggt actggtcagg caataacagt tacaccggaa 13200 gccaatatgg atcaagaatc ctttggtggt gcatcgtgtt gtctgtactg ccgttgccac 13260 atagatcatc caaatcctaa aggattttgt gacttaaaag gtaagtatgt acaaatacct 13320 acaacttgtg ctaatgaccc tgtgggtttt acacttaaaa acacagtctg taccgtctgc 13380 ggtatgtgga aaggttatgg ctgtagttgt gatcaactcc gcgaacccat gcttcagtca 13440 gctgatgcac aatcgttttt aaacgggttt gcggtgtaag tgcagcccgt cttacaccgt 13500 gcggcacagg cactagtact gatgtcgtat acagggcttt tgacatctac aatgataaag 13560 tagctggttt tgctaaattc ctaaaaacta attgttgtcg cttccaagaa aaggacgaag 13620 atgacaattt aattgattct tactttgtag ttaagagaca cactttctct aactaccaac 13680 atgaagaaac aatttataat ttacttaaag attgtccagc tgttgctaaa catgacttct 13740 ttaagtttag aatagacggt gacatggtac cacatatatc acgtcaacgt cttactaaat 13800 acacaatggc agacctcgtc tatgctttaa ggcattttga tgaaggtaat tgtgacacat 13860 taaaagaaat acttgtcaca tacaattgtt gtgatgatga ttatttcaat aaaaaggact 13920 ggtatgattt tgtagaaaac ccagatatat tacgcgtata cgccaactta ggtgaacgtg 13980 tacgccaagc tttgttaaaa acagtacaat tctgtgatgc catgcgaaat gctggtattg 14040 ttggtgtact gacattagat aatcaagatc tcaatggtaa ctggtatgat ttcggtgatt 14100 tcatacaaac cacgccaggt agtggagttc ctgttgtaga ttcttattat tcattgttaa 14160 tgcctatatt aaccttgacc agggctttaa ctgcagagtc acatgttgac actgacttaa 14220 caaagcctta cattaagtgg gatttgttaa aatatgactt cacggaagag aggttaaaac 14280 tctttgaccg ttattttaaa tattgggatc agacatacca cccaaattgt gttaactgtt 14340 tggatgacag atgcattctg cattgtgcaa actttaatgt tttattctct acagtgttcc 14400 cacttacaag ttttggacca ctagtgagaa aaatatttgt tgatggtgtt ccatttgtag 14460 tttcaactgg ataccacttc agagagctag gtgttgtaca taatcaggat gtaaacttac 14520 atagctctag acttagtttt aaggaattac ttgtgtatgc tgctgaccct gctatgcacg 14580 ctgcttctgg taatctatta ctagataaac gcactacgtg cttttcagta gctgcactta 14640 ctaacaatgt tgcttttcaa actgtcaaac ccggtaattt taacaaagac ttctatgact 14700 ttgctgtgtc taagggtttc tttaaggaag gaagttctgt tgaattaaaa cacttcttct 14760 ttgctcagga tggtaatgct gctatcagcg attatgacta ctatcgttat aatctaccaa 14820 caatgtgtga tatcagacaa ctactatttg tagttgaagt tgttgataag tactttgatt 14880 gttacgatgg tggctgtatt aatgctaacc aagtcatcgt caacaaccta gacaaatcag 14940 ctggttttcc atttaataaa tggggtaagg ctagacttta ttatgattca atgagttatg 15000 aggatcaaga tgcacttttc gcatatacaa aacgtaatgt catccctact ataactcaaa 15060 tgaatcttaa gtatgccatt agtgcaaaga atagagctcg caccgtagct ggtgtctcta 15120 tctgtagtac tatgaccaat agacagtttc atcaaaaatt attgaaatca atagccgcca 15180 ctagaggagc tactgtagta attggaacaa gcaaattcta tggtggttgg cacaacatgt 15240 taaaaactgt ttatagtgat gtagaaaacc ctcaccttat gggttgggat tatcctaaat 15300 gtgatagagc catgcctaac atgcttagaa ttatggcctc acttgttctt gctcgcaaac 15360 atacaacgtg ttgtagcttg tcacaccgtt tctatagatt agctaatgag tgtgctcaag 15420 tattgagtga aatggtcatg tgtggcggtt cactatatgt taaaccaggt ggaacctcat 15480 caggagatgc cacaactgct tatgctaata gtgtttttaa catttgtcaa gctgtcacgg 15540 ccaatgttaa tgcactttta tctactgatg gtaacaaaat tgccgataag tatgtccgca 15600 atttacaaca cagactttat gagtgtctct atagaaatag agatgttgac acagactttg 15660 tgaatgagtt ttacgcatat ttgcgtaaac atttctcaat gatgatactc tctgacgatg 15720 ctgttgtgtg tttcaatagc acttatgcat ctcaaggtct agtggctagc ataaagaact 15780 ttaagtcagt tctttattat caaaacaatg tttttatgtc tgaagcaaaa tgttggactg 15840 agactgacct tactaaagga cctcatgaat tttgctctca acatacaatg ctagttaaac 15900 agggtgatga ttatgtgtac cttccttacc cagatccatc aagaatccta ggggccggct 15960 gttttgtaga tgatatcgta aaaacagatg gtacacttat gattgaacgg ttcgtgtctt 16020 tagctataga tgcttaccca cttactaaac atcctaatca ggagtatgct gatgtctttc 16080 atttgtactt acaatacata agaaagctac atgatgagtt aacaggacac atgttagaca 16140 tgtattctgt tatgcttact aatgataaca cttcaaggta ttgggaacct gagttttatg 16200 aggctatgta cacaccgcat acagtcttac aggctgttgg ggcttgtgtt ctttgcaatt 16260 cacagacttc attaagatgt ggtgcttgca tacgtagacc attcttatgt tgtaaatgct 16320 gttacgacca tgtcatatca acatcacata aattagtctt gtctgttaat ccgtatgttt 16380 gcaatgctct aggttgtgat gtcacagatg tgactcaact ttacttagga ggtatgagct 16440 attattgtaa atcacataaa ccacccatta gttttccatt gtgtgctaat ggacaagttt 16500 ttggtttata taaaaataca tgtgttggta gcgataatgt tactgacttt aatgcaattg 16560 caacatgtga ctggacaaat gctggtgatt acattttagc taacacctgt actgaaagac 16620 tcaagctttt tgcagcagaa acgctcaaag ctactgagga gacatttaaa ctgtcttatg 16680 gtattgctac tgtacgtgaa gtgctgtctg acagagaatt acatctttca tgggaagttg 16740 gtaaacctag accaccactt aaccgaaatt atgtctttac tggttatcgt gtaactaaaa 16800 acagtaaagt acaaatagga gagtacacct ttgaaaaagg tgactatggt gatgctgttg 16860 tttaccgagg tacaacaact tacaaattaa atgttggtga ttattttgtg ctgacatcac 16920 atacagtaat gccattaagt gcacctacac tagtgccaca agagcactat gttagaatta 16980 ctggcttata cccaacactc aatatctcat atgagttttc tagcaatgtt gcaaattatc 17040 aaaaggttgg tatgcaaaag tattctacac tccagggacc acctggtact ggtaagagtc 17100 attttgctat tggcctagct ctctactacc cttctgctcg catagtgtat acagcttgct 17160 ctcatgccgc tgttgatgca ctatgtgaga aggcattaaa atatttgcct atagataaat 17220 gtagtagaat tatacctgca cgtgctcgtg tagagtgttt tgataaattc aaagtgaatt 17280 caacattaga acagtatgtc ttttgtactg taaatgcatt gcctgagacg acagcagata 17340 tagttgtctt tgatgaaatt tcaatggcca caaattatga tttgagtgtt gtcaatgcca 17400 gattacgtgc taagcactat gtgtacattg gcgaccctgc tcaattacct gcaccacgca 17460 cattgctaac taagggcaca ctagaaccag aatatttcaa ttcagtgtgt agacttatga 17520 aaactatagg tccagacatg ttcctcggaa cttgtcggcg ttgtcctgct gaaattgttg 17580 acactgtgag tgctttggtt tatgataata agcttaaagc acataaagac aaatcagctc 17640 aatgctttaa aatgttttat aagggtgtta tcacgcatga tgtttcatct gcaattaaca 17700 ggccacaaat aggcgtggta agagaattcc ttacacgtaa ccctgcttgg agaaaagctg 17760 tctttatttc accttataat tcacagaatg ctgtagcctc aaagattttg ggactaccaa 17820 ctcaaactgt tgattcatca cagggctcag aatatgacta tgtcatattc actcaaacca 17880 ctgaaacagc tcactcttgt aatgtaaaca gatttaatgt tgctattacc agagcaaaag 17940 taggcatact ttgcataatg tctgatagag acctttatga caagttgcaa tttacaagtc 18000 ttgaaattcc acgtaggaat gtggcaactt tacaagctga aaatgtaaca ggactcttta 18060 aagattgtag taaggtaatc actgggttac atcctacaca ggcacctaca cacctcagtg 18120 ttgacactaa attcaaaact gaaggtttat gtgttgacat acctggcata cctaaggaca 18180 tgacctatag aagactcatc tctatgatgg gttttaaaat gaattatcaa gttaatggtt 18240 accctaacat gtttatcacc cgcgaagaag ctataagaca tgtacgtgca tggattggct 18300 tcgatgtcga ggggtgtcat gctactagag aagctgttgg taccaattta cctttacagc 18360 taggtttttc tacaggtgtt aacctagttg ctgtacctac aggttatgtt gatacaccta 18420 ataatacaga tttttccaga gttagtgcta aaccaccgcc tggagatcaa tttaaacacc 18480 tcataccact tatgtacaaa ggacttcctt ggaatgtagt gcgtataaag attgtacaaa 18540 tgttaagtga cacacttaaa aatctctctg acagagtcgt atttgtctta tgggcacatg 18600 gctttgagtt gacatctatg aagtattttg tgaaaatagg acctgagcgc acctgttgtc 18660 tatgtgatag acgtgccaca tgcttttcca ctgcttcaga cacttatgcc tgttggcatc 18720 attctattgg atttgattac gtctataatc cgtttatgat tgatgttcaa caatggggtt 18780 ttacaggtaa cctacaaagc aaccatgatc tgtattgtca agtccatggt aatgcacatg 18840 tagctagttg tgatgcaatc atgactaggt gtctagctgt ccacgagtgc tttgttaagc 18900 gtgttgactg gactattgaa tatcctataa ttggtgatga actgaagatt aatgcggctt 18960 gtagaaaggt tcaacacatg gttgttaaag ctgcattatt agcagacaaa ttcccagttc 19020 ttcacgacat tggtaaccct aaagctatta agtgtgtacc tcaagctgat gtagaatgga 19080 agttctatga tgcacagcct tgtagtgaca aagcttataa aatagaagaa ttattctatt 19140 cttatgccac acattctgac aaattcacag atggtgtatg cctattttgg aattgcaatg 19200 tcgatagata tcctgctaat tccattgttt gtagatttga cactagagtg ctatctaacc 19260 ttaacttgcc tggttgtgat ggtggcagtt tgtatgtaaa taaacatgca ttccacacac 19320 cagcttttga taaaagtgct tttgttaatt taaaacaatt accatttttc tattactctg 19380 acagtccatg tgagtctcat ggaaaacaag tagtgtcaga tatagattat gtaccactaa 19440 agtctgctac gtgtataaca cgttgcaatt taggtggtgc tgtctgtaga catcatgcta 19500 atgagtacag attgtatctc gatgcttata acatgatgat ctcagctggc tttagcttgt 19560 gggtttacaa acaatttgat acttataacc tctggaacac ttttacaaga cttcagagtt 19620 tagaaaatgt ggcttttaat gttgtaaata agggacactt tgatggacaa cagggtgaag 19680 taccagtttc tatcattaat aacactgttt acacaaaagt tgatggtgtt gatgtagaat 19740 tgtttgaaaa taaaacaaca ttacctgtta atgtagcatt tgagctttgg gctaagcgca 19800 acattaaacc agtaccagag gtgaaaatac tcaataattt gggtgtggac attgctgcta 19860 atactgtgat ctgggactac aaaagagatg ctccagcaca tatatctact attggtgttt 19920 gttctatgac tgacatagcc aagaaaccaa ctgaaacgat ttgtgcacca ctcactgtct 19980 tttttgatgg tagagttgat ggtcaagtag acttatttag aaatgcccgt aatggtgttc 20040 ttattacaga aggtagtgtt aaaggtttac aaccatctgt aggtcccaaa caagctagtc 20100 ttaatggagt cacattaatt ggagaagccg taaaaacaca gttcaattat tataagaaag 20160 ttgatggtgt tgtccaacaa ttacctgaaa cttactttac tcagagtaga aatttacaag 20220 aatttaaacc caggagtcaa atggaaattg atttcttaga attagctatg gatgaattca 20280 ttgaacggta taaattagaa ggctatgcct tcgaacatat cgtttatgga gattttagtc 20340 atagtcagtt aggtggttta catctactga ttggactagc taaacgtttt aaggaatcac 20400 cttttgaatt agaagatttt attcctatgg acagtacagt taaaaactat ttcataacag 20460 atgcgcaaac aggttcatct aagtgtgtgt gttctgttat tgatttatta cttgatgatt 20520 ttgttgaaat aataaaatcc caagatttat ctgtagtttc taaggttgtc aaagtgacta 20580 ttgactatac agaaatttca tttatgcttt ggtgtaaaga tggccatgta gaaacatttt 20640 acccaaaatt acaatctagt caagcgtggc aaccgggtgt tgctatgcct aatctttaca 20700 aaatgcaaag aatgctatta gaaaagtgtg accttcaaaa ttatggtgat agtgcaacat 20760 tacctaaagg cataatgatg aatgtcgcaa aatatactca actgtgtcaa tatttaaaca 20820 cattaacatt agctgtaccc tataatatga gagttataca ttttggtgct ggttctgata 20880 aaggagttgc accaggtaca gctgttttaa gacagtggtt gcctacgggt acgctgcttg 20940 tcgattcaga tcttaatgac tttgtctctg atgcagattc aactttgatt ggtgattgtg 21000 caactgtaca tacagctaat aaatgggatc tcattattag tgatatgtac gaccctaaga 21060 ctaaaaatgt tacaaaagaa aatgactcta aagagggttt tttcacttac atttgtgggt 21120 ttatacaaca aaagctagct cttggaggtt ccgtggctat aaagataaca gaacattctt 21180 ggaatgctga tctttataag ctcatgggac acttcgcatg gtggacagcc tttgttacta 21240 atgtgaatgc gtcatcatct gaagcatttt taattggatg taattatctt ggcaaaccac 21300 gcgaacaaat agatggttat gtcatgcatg caaattacat attttggagg aatacaaatc 21360 caattcagtt gtcttcctat tctttatttg acatgagtaa atttcccctt aaattaaggg 21420 gtactgctgt tatgtcttta aaagaaggtc aaatcaatga tatgatttta tctcttctta 21480 gtaaaggtag acttataatt agagaaaaca acagagttgt tatttctagt gatgttcttg 21540 ttaacaacta aacgaacaat gtttgttttt cttgttttat tgccactagt ctctattcag 21600 tgtgttaatc ttacaaccag aactcaatta ccccctgcat acactaattc tttcacacgt 21660 ggtgtttatt accctgacaa agttttcaga tcctcagttt tacattcaac tcaggacttg 21720 ttcttacctt tcttttccaa tgttacttgg ttccatgcta tacatgtctc tgggaccaat 21780 ggtactaaga ggtttgataa ccctgtccta ccatttaatg atggtgttta ttttgcttcc 21840 actgagaagt ctaacataat aagaggctgg atttttggta ctactttaga ttcgaagacc 21900 cagtccctac ttattgttaa taacgctact aatgttgtta ttaaagtctg tgaatttcaa 21960 ttttgtaatg atccattttt gggtgtttat taccacaaaa acaacaaaag ttgtatggaa 22020 agtgagttca gagtttattc tagtgcgaat aattgcactt ttgaatatgt ctctcagcct 22080 tttcttatgg accttgaagg aaaacagggt aatttcaaaa atcttaggga atttgtgttt 22140 aagaatattg atggttattt taaaatatat tctaagcaca cgcctattaa tttagtgcgt 22200 gatctccctc agggtttttc ggctttagaa ccattggtag atttgccaat aggtattaac 22260 atcactaggt ttcaaacttt acttgcttta catagaagtt atttgactcc tggtgattct 22320 tcttcaggtt ggacagctgg tgctgcagct tattatgtgg gttatcttca acctaggact 22380 tttctattaa aatataatga aaatggaacc attacagatg ctgtagactg tgcacttgac 22440 cctctctcag aaacaaagtg tacgttgaaa tccttcactg tagaaaaagg aatctatcaa 22500 acttctaact ttagagtcca accaacagaa tctattgtta gatttcctaa tattacaaac 22560 ttgtgccctt ttggtgaagt ttttaacgcc accagatttg catctgttta tgcttggaac 22620 aggaagagaa tcagcaactg tgttgctgat tattctgtcc tatataattc cgcatcattt 22680 tccactttta agtgttatgg agtgtctcct actaaattaa atgatctctg ctttactaat 22740 gtctatgcag attcatttgt aattagaggt gatgaagtca gacaaatcgc tccagggcaa 22800 actggaaaga ttgctgatta taattataaa ttaccagatg attttacagg ctgcgttata 22860 gcttggaatt ctaacaatct tgattctaag gttggtggta attataatta ccggtataga 22920 ttgtttagga agtctaatct caaacctttt gagagagata tttcaactga aatctatcag 22980 gccggtagca caccttgtaa tggtgttgaa ggttttaatt gttactttcc tttacaatca 23040 tatggtttcc aacccactaa tggtgttggt taccaaccat acagagtagt agtactttct 23100 tttgaacttc tacatgcacc agcaactgtt tgtggaccta aaaagtctac taatttggtt 23160 aaaaacaaat gtgtcaattt caacttcaat ggtttaacag gcacaggtgt tcttactgag 23220 tctaacaaaa agtttctgcc tttccaacaa tttggcagag acattgctga cactactgat 23280 gctgtccgtg atccacagac acttgagatt cttgacatta caccatgttc ttttggtggt 23340 gtcagtgtta taacaccagg aacaaatact tctaaccagg ttgctgttct ttatcagggt 23400 gttaactgca cagaagtccc tgttgctatt catgcagatc aacttactcc tacttggcgt 23460 gtttattcta caggttctaa tgtttttcaa acacgtgcag gctgtttaat aggggctgaa 23520 catgtcaaca actcatatga gtgtgacata cccattggtg caggtatatg cgctagttat 23580 cagactcaga ctaattctcc tcggcgggca cgtagtgtag ctagtcaatc catcattgcc 23640 tacactatgt cacttggtgc agaaaattca gttgcttact ctaataactc tattgccata 23700 cccacaaatt ttactattag tgttaccaca gaaattctac cagtgtctat gaccaagaca 23760 tcagtagatt gtacaatgta catttgtggt gattcaactg aatgcagcaa tcttttgttg 23820 caatatggca gtttttgtac acaattaaac cgtgctttaa ctggaatagc tgttgaacaa 23880 gacaaaaaca cccaagaagt ttttgcacaa gtcaaacaaa tttacaaaac accaccaatt 23940 aaagattttg gtggttttaa tttttcacaa atattaccag atccatcaaa accaagcaag 24000 aggtcattta ttgaagatct acttttcaac aaagtgacac ttgcagatgc tggcttcatc 24060 aaacaatatg gtgattgcct tggtgatatt gctgctagag acctcatttg tgcacaaaag 24120 tttaacggcc ttactgtttt gccacctttg ctcacagatg aaatgattgc tcaatacact 24180 tctgcactgt tagcgggtac aatcacttct ggttggacct ttggtgcagg tgctgcatta 24240 caaataccat ttgctatgca aatggcttat aggtttaatg gtattggagt tacacagaat 24300 gttctctatg agaaccaaaa attgattgcc aaccaattta atagtgctat tggcaaaatt 24360 caagactcac tttcttccac agcaagtgca cttggaaaac ttcaagatgt ggtcaaccaa 24420 aatgcacaag ctttaaacac gcttgttaaa caacttagct ccaattttgg tgcaatttca 24480 agtgttttaa atgatatcct ttcacgtctt gacaaagttg aggctgaagt gcaaattgat 24540 aggttgatca caggcagact tcaaagtttg cagacatatg tgactcaaca attaattaga 24600 gctgcagaaa tcagagcttc tgctaatctt gctgctacta aaatgtcaga gtgtgtactt 24660 ggacaatcaa aaagagttga tttttgtgga aagggctatc atcttatgtc cttccctcag 24720 tcagcacctc atggtgtagt cttcttgcat gtgacttatg tccctgcaca agaaaagaac 24780 ttcacaactg ctcctgccat ttgtcatgat ggaaaagcac actttcctcg tgaaggtgtc 24840 tttgtttcaa atggcacaca ctggtttgta acacaaagga atttttatga accacaaatc 24900 attactacag acaacacatt tgtgtctggt aactgtgatg ttgtaatagg aattgtcaac 24960 aacacagttt atgatccttt gcaacctgaa ttagactcat tcaaggagga gttagataaa 25020 tattttaaga atcatacatc accagatgtt gatttaggtg acatctctgg cattaatgct 25080 tcagttgtaa acattcaaaa agaaattgac cgcctcaatg aggttgccaa gaatttaaat 25140 gaatctctca tcgatctcca agaacttgga aagtatgagc agtatataaa atggccatgg 25200 tacatttggc taggttttat agctggcttg attgccatag taatggtgac aattatgctt 25260 tgctgtatga ccagttgctg tagttgtctc aagggctgtt gttcttgtgg atcctgctgc 25320 aaatttgatg aagacgactc tgagccagtg ctcaaaggag tcaaattaca ttacacataa 25380 acgaacttat ggatttgttt atgagaatct tcacaattgg aactgtaact ttgaagcaag 25440 gtgaaatcaa ggatgctact ccttcagatt ttgttcgcgc tactgcaacg ataccgatac 25500 aagcctcact ccctttcgga tggcttattg ttggcgttgc acttcttgct gtttttcata 25560 gcgcttccaa aatcataacc ctcaaaaaga gatggcaact agcactctcc aagggtgttc 25620 actttgtttg caacttgctg ttgttgtttg taacagttta ctcacacctt ttgctcgttg 25680 ctgctggcct tgaagcccct tttctctatc tttatgcttt agtctacttc ttgcagagta 25740 taaactttgt aagaataata atgaggcttt ggctttgctg gaaatgccgt tccaaaaacc 25800 cattacttta tgatgccaac tattttcttt gctggcatac taattgttac gactattgta 25860 taccttacaa tagtgtaact tcttcaattg tcattacttc aggtgatggc acaacaagtc 25920 ctatttctga acatgactac cagattggtg gttatactga aaaatgggaa tctggagtaa 25980 aagactgtgt tgtattacac agttacttca cttcagacta ttaccagctg tactcaactc 26040 aattgagtac agacactggt gttgaacatg ttaccttctt catctacaat aaaattgttg 26100 atgagcctga agaacatgtc caaattcaca caatcgacgg ttcatccgga gttgttaatc 26160 cagtaatgga accaatttat gatgaaccga cgacgactac tagcgtgcct ttgtaagcac 26220 aagctgatga gtacgaactt atgtactcat tcgtttcgga agagacaggt acgttaatag 26280 ttaatagcgt acttcttttt cttgctttcg tggtattctt gctagttaca ctagccatcc 26340 ttactgcgct tcgattgtgt gcgtactgct gcaatattgt taacgtgagt cttgtaaaac 26400 cttcttttta cgtttactct cgtgttaaaa atctgaattc ttctagagtt cctgatcttc 26460 tggtctaaac gaactaaata ttatattagt ttttctgttt ggaactttaa ttttagccat 26520 ggtagattcc aacggtacta ttaccgttga agagcttaaa aagctccttg aacaatggaa 26580 cctagtaata ggtttcctat tccttacatg gatttgtctt ctacaatttg cctatgccaa 26640 caggaatagg tttttgtata taattaagtt aatttttctc tggctgttat ggccagtaac 26700 tttagcttgt tttgtgcttg ctgctgttta cagaataaat tggatcaccg gtggaattgc 26760 tatcgcaatg gcttgtcttg taggcttgat gtggctcagc tacttcattg cttctttcag 26820 actgtttgcg cgtacgcgtt ccatgtggtc attcaatcca gaaactaaca ttcttctcaa 26880 cgtgccactc catggcacta ttctgaccag accgcttcta gaaagtgaac tcgtaatcgg 26940 agctgtgatc cttcgtggac atcttcgtat tgctggacac catctaggac gctgtgacat 27000 caaggacctg cctaaagaaa tcactgttgc tacatcacga acgctttctt attacaaatt 27060 gggagcttcg cagcgtgtag caggtgactc aggttttgct gcatacagtc gctacaggat 27120 tggcaactat aaattaaaca cagaccattc cagtagcagt gacaatattg ctttgcttgt 27180 acagtaagtg acaacagatg tttcatctcg ttgactttca ggttactata gcagagatat 27240 tactaattat tatgaggact tttaaagttt ccatttggaa tcttgattac atcataaacc 27300 tcataattaa aaatttatct aagtcactaa ctgagaataa atattctcaa ttagatgaag 27360 agcaaccaat ggagattgat taaacgaaca tgaaaattat tcttttcttg gcactgataa 27420 cactcgctac ttgtgagctt tatcactacc aagagtgtgt tagaggtaca acagtacttt 27480 taaaagaacc ttgctcttct ggaacatacg agggcaattc accatttcat cctctagctg 27540 ataacaaatt tgcactgact tgctttagca ctcaatttgc ttttgcttgt cctgacggcg 27600 taaaacacgt ctatcagtta cgtgccagat cagtttcacc taaactgttc atcagacaag 27660 aggaagttca agaactttac tctccaattt ttcttattgt tgcggcaata gtgtttataa 27720 cactttgctt cacactcaaa agaaagacag aatgattgaa ctttcattaa ttgacttcta 27780 tttgtgcttt ttagcctttc tgctattcct tgttttaatt atgcttatta tcttttggtt 27840 ctcacttgaa ctgcaagatc ataatgaaac ttgtcacgcc taaacgaaca tgaaatttct 27900 tgttttctta ggaatcatca caactgtagc tgcatttcac caagaatgta gtttacagtc 27960 atgtactcaa catcaaccat atgtagttga tgacccgtgt cctattcact tctattctaa 28020 atggtatatt agagtaggag ctagaaaatc agcaccttta attgaattgt gcgtggatga 28080 ggctggttct aaatcaccca ttcagtacat cgatatcggt aattatacag tttcctgttt 28140 accttttaca attaattgcc aggaacctaa attgggtagt cttgtagtgc gttgttcgtt 28200 ctatgaagac tttttagagt atcatgacgt tcgtgttgtt ttagatttca tctaaacgaa 28260 caaactataa tgtctgataa tggaccccaa aatcagcgaa atgcaccccg cattacgttt 28320 ggtggaccct cagattcaac tggcagtaac cagaatggag aacgcagtgg ggcgcgatca 28380 aaacaacgtc ggccccaagg tttacccaat aatactgcgt cttggttcac cgctctcact 28440 caacatggca aggaagacct taaattccct cgaggacaag gcgttccaat taacaccaat 28500 agcagtccag atgaccaaat tggctactac cgaagagcta ccagacgaat tcgtggtggt 28560 gacggtaaaa tgaaagatct cagtccaaga tggtatttct actacctagg aactgggcca 28620 gaagctggac ttccctatgg tgctaacaaa gacggcatca tatgggttgc aactgaggga 28680 gccttgaata caccaaaaga tcacattggc acccgcaatc ctgctaacaa tgctgcaatc 28740 gtgctacaac ttcctcaagg aacaacattg ccaaaaggct tctacgcaga agggagcaga 28800 ggcggcagtc aagcctcttc tcgttcctca tcacgtagtc gcaacagttc aagaaattca 28860 actccaggca gcagtagggg aatttctcct gctagaatgg ctggcaatgg cggtgatgct 28920 gctcttgctt tgctgctgct tgacagattg aaccagcttg agagcaaaat gtctggtaaa 28980 ggccaacaac aacaaggcca aactgtcact aagaaatctg ctgctgaggc ttctaagaag 29040 cctcggcaaa aacgtactgc cactaaagca tacaatgtaa cacaagcttt cggcagacgt 29100 ggtccagaac aaacccaagg aaattttggg gaccaggaac taatcagaca aggaactgat 29160 tacaaacatt ggccgcaaat tgcacaattt gcccccagcg cttcagcgtt cttcggaatg 29220 tcgcgcattg gcatggaagt cacaccttcg ggaacgtggt tgacctacac aggtgccatc 29280 aaattggatg acaaagatcc aaatttcaaa gatcaagtca ttttgctgaa taagcatatt 29340 gacgcataca aaacatttcc accaacagag cctaaaaagg acaaaaagaa gaaggctgat 29400 gaaactcaag ccttaccgca gagacagaag aaacagcaaa ctgtgactct tcttcctgct 29460 gcagatttgg atgatttctc caaacaattg caacaatcca tgagcagtgc tgactcaact 29520 caggcctaaa ctcatgcaga ccacacaagg cagatgggct atataaacgt tttcgctttt 29580 ccgtttacga tatatagtct actcttgtgc agaatgaatt ctcgtaacta catagcacaa 29640 gtagatgtag ttaactttaa tctcacatag caatctttaa tcagtgtgta acattaggga 29700 ggacttgaaa gagccaccac attttcaccg aggccacgcg gagtacgatc gagtgtacag 29760 tgaacaatgc tagggagagc tgcctatatg gaagagccct aatgtgtaaa attaatttta 29820 gtagtgctat cc 29832 <210> 25 <211> 1273 <212> PRT <213> SARS-CoV2 <400> 25 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ile Gln Cys Val 1 5 10 15 Asn Leu Thr Thr Arg Thr Gln Leu Pro Pro Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Hes Val Ser Gly Thr Asn Gly Thr Lys Arg Phe Asp 65 70 75 80 Asn Pro Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu 85 90 95 Lys Ser Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser 100 105 110 Lys Thr Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile 115 120 125 Lys Val Cys Glu Phe Gln Phe Cys Asn Asp Pro Phe Leu Gly Val Tyr 130 135 140 Tyr Hes Lys Asn Asn Lys Ser Cys Met Glu Ser Glu Phe Arg Val Tyr 145 150 155 160 Ser Ser Ala Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu 165 170 175 Met Asp Leu Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Arg Glu Phe 180 185 190 Val Phe Lys Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr 195 200 205 Pro Ile Asn Leu Val Arg Asp Leu Pro Gln Gly Phe Ser Ala Leu Glu 210 215 220 Pro Leu Val Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Thr 225 230 235 240 Leu Leu Ala Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser 245 250 255 Gly Trp Thr Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro 260 265 270 Arg Thr Phe Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala 275 280 285 Val Asp Cys Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys 290 295 300 Ser Phe Thr Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Val 305 310 315 320 Gln Pro Thr Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys 325 330 335 Pro Phe Gly Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala 340 345 350 Trp Asn Arg Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Val Leu 355 360 365 Tyr Asn Ser Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro 370 375 380 Thr Lys Leu Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe 385 390 395 400 Val Ile Arg Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly 405 410 415 Lys Ile Ala Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys 420 425 430 Val Ile Ala Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn 435 440 445 Tyr Asn Tyr Arg Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe 450 455 460 Glu Arg Asp Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys 465 470 475 480 Asn Gly Val Glu Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly 485 490 495 Phe Gln Pro Thr Asn Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val 500 505 510 Leu Ser Phe Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys 515 520 525 Lys Ser Thr Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn 530 535 540 Gly Leu Thr Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu 545 550 555 560 Pro Phe Gln Gln Phe Gly Arg Asp Ile Ala Asp Thr Thr Asp Ala Val 565 570 575 Arg Asp Pro Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe 580 585 590 Gly Gly Val Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val 595 600 605 Ala Val Leu Tyr Gln Gly Val Asn Cys Thr Glu Val Pro Val Ala Ile 610 615 620 Hes Ala Asp Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser 625 630 635 640 Asn Val Phe Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Hes Val 645 650 655 Asn Asn Ser Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala 660 665 670 Ser Tyr Gln Thr Gln Thr Asn Ser Pro Arg Arg Ala Arg Ser Val Ala 675 680 685 Ser Gln Ser Ile Ile Ala Tyr Thr Met Ser Leu Gly Ala Glu Asn Ser 690 695 700 Val Ala Tyr Ser Asn Asn Ser Ile Ala Ile Pro Thr Asn Phe Thr Ile 705 710 715 720 Ser Val Thr Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val 725 730 735 Asp Cys Thr Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu 740 745 750 Leu Leu Gln Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr 755 760 765 Gly Ile Ala Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln 770 775 780 Val Lys Gln Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe 785 790 795 800 Asn Phe Ser Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser 805 810 815 Phe Ile Glu Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly 820 825 830 Phe Ile Lys Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp 835 840 845 Leu Ile Cys Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu 850 855 860 Leu Thr Asp Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly 865 870 875 880 Thr Ile Thr Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile 885 890 895 Pro Phe Ala Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr 900 905 910 Gln Asn Val Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn 915 920 925 Ser Ala Ile Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala 930 935 940 Leu Gly Lys Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn 945 950 955 960 Thr Leu Val Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val 965 970 975 Leu Asn Asp Ile Leu Ser Arg Leu Asp Lys Val Glu Ala Glu Val Gln 980 985 990 Ile Asp Arg Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val 995 1000 1005 Thr Gln Gln Leu Ile Arg Ala Ala Glu Ile Arg Ala Ser Ala Asn 1010 1015 1020 Leu Ala Ala Thr Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys 1025 1030 1035 Arg Val Asp Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro 1040 1045 1050 Gln Ser Ala Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val 1055 1060 1065 Pro Ala Gln Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes 1070 1075 1080 Asp Gly Lys Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn 1085 1090 1095 Gly Thr Hes Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln 1100 1105 1110 Ile Ile Thr Thr Asp Asn Thr Phe Val Ser Gly Asn Cys Asp Val 1115 1120 1125 Val Ile Gly Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro 1130 1135 1140 Glu Leu Asp Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn 1145 1150 1155 Hes Thr Ser Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn 1160 1165 1170 Ala Ser Val Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu 1175 1180 1185 Val Ala Lys Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu 1190 1195 1200 Gly Lys Tyr Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu 1205 1210 1215 Gly Phe Ile Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met 1220 1225 1230 Leu Cys Cys Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys 1235 1240 1245 Ser Cys Gly Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro 1250 1255 1260 Val Leu Lys Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 26 <211> 29816 <212> ADN <213> SARS-CoV2 <400> 26 actttcgatc tcttgtagat ctgttctcta aacgaacttt aaaatctgtg tggctgtcac 60 tcggctgcat gcttagtgca ctcacgcagt ataattaata actaattact gtcgttgaca 120 ggacacgagt aactcgtcta tcttctgcag gctgcttacg gtttcgtccg tgttgcagcc 180 gatcatcagc acatctaggt tttgtccggg tgtgaccgaa aggtaagatg gagagccttg 240 tccctggttt caacgagaaa acacacgtcc aactcagttt gcctgtttta caggttcgcg 300 acgtgctcgt acgtggcttt ggagactccg tggaggaggt cttatcagag gcacgtcaac 360 atcttaaaga tggcacttgt ggcttagtag aagttgaaaa aggcgttttg cctcaacttg 420 aacagcccta tgtgttcatc aaacgttcgg atgctcgaac tgcacctcat ggtcatgtta 480 tggttgagct ggtagcagaa ctcgaaggca ttcagtacgg tcgtagtggt gagacacttg 540 gtgtccttgt ccctcatgtg ggcgaaatac cagtggctta ccgcaaggtt cttcttcgta 600 agaacggtaa taaaggagct ggtggccata gttacggcgc cgatctaaag tcatttgact 660 taggcgacga gcttggcact gatccttatg aagattttca agaaaactgg aacactaaac 720 atagcagtgg tgttacccgt gaactcatgc gtgagcttaa cggaggggca tacactcgct 780 atgtcgataa caacttctgt ggccctgatg gctaccctct tgagtgcatt aaagaccttc 840 tagcacgtgc tggtaaagct tcatgcactt tgtccgaaca actggacttt attgacacta 900 agaggggtgt atactgctgc cgtgaacatg agcatgaaat tgcttggtac acggaacgtt 960 ctgaaaagag ctatgaattg cagacacctt ttgaaattaa attggcaaag aaatttgaca 1020 tcttcaatgg ggaatgtcca aattttgtat ttcccttaaa ttccataatc aagactattc 1080 aaccaagggt tgaaaagaaa aagcttgatg gctttatggg tagaattcga tctgtctatc 1140 cagttgcgtc accaaatgaa tgcaaccaaa tgtgcctttc aactctcatg aagtgtgatc 1200 attgtggtga aacttcatgg cagacgggcg attttgttaa agccacttgc gaattttgtg 1260 gcactgagaa tttgactaaa gaaggtgcca ctacttgtgg ttacttaccc caaaatgctg 1320 ttgttaaaat ttattgtcca gcatgtcaca attcagaagt aggacctgag catagtcttg 1380 ccgaatacca taatgaatct ggcttgaaaa ccattcttcg taagggtggt cgcactattg 1440 cctttggagg ctgtgtgttc tcttatgttg gttgccataa caagtgtgcc tattgggttc 1500 cacgtgctag cgctaacata ggttgtaacc atacaggtgt tgttggagaa ggttccgaag 1560 gtcttaatga caaccttctt gaaatactcc aaaaagagaa agtcaacatc aatattgttg 1620 gtgactttaa acttaatgaa gagatcgcca ttattttggc atctttttct gcttccacaa 1680 gtgcttttgt ggaaactgtg aaaggtttgg attataaagc attcaaacaa attgttgaat 1740 cctgtggtaa ttttaaagtt acaaaaggaa aagctaaaaa aggtgcctgg aatattggtg 1800 aacagaaatc aatactgagt cctctttatg catttgcatc agaggctgct cgtgttgtac 1860 gatcaatttt ctcccgcact cttgaaactg ctcaaaattc tgtgcgtgtt ttacagaagg 1920 ccgctataac aatactagat ggaatttcac agtattcact gagactcatt gatgctatga 1980 tgttcacatc tgatttggct actaacaatc tagttgtaat ggcctacatt acaggtggtg 2040 ttgttcagtt gacttcgcag tggctaacta acatctttgg cactgtttat gaaaaactca 2100 aacccgtcct tgattggctt gaagagaagt ttaaggaagg tgtagagttt cttagagacg 2160 gttgggaaat tgttaaattt atctcaacct gtgcttgtga aattgtcggt ggacaaattg 2220 tcacctgtgc aaaggaaatt aaggagagtg ttcagacatt ctttaagctt gtaaataaat 2280 ttttggcttt gtgtgctgac tctatcatta ttggtggagc taaacttaaa gccttgaatt 2340 taggtgaaac atttgttacg cactcaaagg gattgtacag aaagtgtgtt aaatccagag 2400 aagaaactgg cctactcatg cctctaaaag ccccaaaaga aattatcttc ttagagggag 2460 aaacacttcc cacagaagtg ttaacagagg aagttgtctt gaaaactggt gatttacaac 2520 cattagaaca acctactagt gaagctgttg aagctccact ggttggtaca ccagtttgta 2580 ttaacgggct tatgttgctc gaaatcaaag acacagaaaa gtactgtgcc cttgcaccta 2640 atatgatggt aacaaacaat accttcacac tcaaaggcgg tgcaccaaca aaggttactt 2700 ttggtgatga cactgtgata gaagtgcaag gttacaagag tgtgaatatc acttttgaac 2760 ttgatgaaag gattgataaa gtacttaatg agaagtgctc tgcctataca gttgaactcg 2820 gtacagaagt aaatgagttc gcctgtgttg tggcagatgc tgtcataaaa actttgcaac 2880 cagtatctga attacttaca ccactgggca ttgatttaga tgagtggagt atggctacat 2940 actacttatt tgatgagtct ggtgagttta aattggcttc acatatgtat tgttcttttt 3000 accctccaga tgaggatgaa gaagaaggtg attgtgaaga agaagagttt gagccatcaa 3060 ctcaatatga gtatggtact gaagatgatt accaaggtaa acctttggaa tttggtgcca 3120 cttctgctgc tcttcaacct gaagaagagc aagaagaaga ttggttagat gatgatagtc 3180 aacaaactgt tggtcaacaa gacggcagtg aggacaatca gacaactact attcaaacaa 3240 ttgttgaggt tcaacctcaa ttagagatgg aacttacacc agttgttcag actattgaag 3300 tgaatagttt tagtggttat ttaaaactta ctgacaatgt atacattaaa aatgcagaca 3360 ttgtggaaga agctaaaaag gtaaaaccaa cagtggttgt taatgcagcc aatgtttacc 3420 ttaaacatgg aggaggtgtt gcaggagcct taaataaggc tactaacaat gccatgcaag 3480 ttgaatctga tgattacata gctactaatg gaccacttaa agtgggtggt agttgtgttt 3540 taagcggaca caatcttgct aaacactgtc ttcatgttgt cggcccaaat gttaacaaag 3600 gtgaagacat tcaacttctt aagagtgctt atgaaaattt taatcagcac gaagttctac 3660 ttgcaccatt attatcagct ggtatttttg gtgctgaccc tatacattct ttaagagttt 3720 gtgtagatac tgttcgcaca aatgtctact tagctgtctt tgataaaaat ctctatgaca 3780 aacttgtttc aagctttttg gaaatgaaga gtgaaaagca agttgaacaa aagatcgctg 3840 agattcctaa agaggaagtt aagccattta taactgaaag taaaccttca gttgaacaga 3900 gaaaacaaga tgataagaaa atcaaagctt gtgttgaaga agttacaaca actctggaag 3960 aaactaagtt cctcacagaa aacttgttac tttatattga cattaatggc aatcttcatc 4020 cagattctgc cactcttgtt agtgacattg acatcacttt cttaaagaaa gatgctccat 4080 atatagtggg tgatgttgtt caagagggtg ttttaactgc tgtggttata cctactaaaa 4140 aggctggtgg cactactgaa atgctagcga aagctttgag aaaagtgcca acagacaatt 4200 atataaccac ttacccgggt cagggtttaa atggttacac tgtagaggag gcaaagacag 4260 tgcttaaaaa gtgtaaaagt gccttttaca ttctaccatc tattatctct aatgagaagc 4320 aagaaattct tggaactgtt tcttggaatt tgcgagaaat gcttgcacat gcagaagaaa 4380 cacgcaaatt aatgcctgtc tgtgtggaaa ctaaagccat agtttcaact atacagcgta 4440 aatataaggg tattaaaata caagagggtg tggttgatta tggtgctaga ttttactttt 4500 acaccagtaa aacaactgta gcgtcactta tcaacacact taacgatcta aatgaaactc 4560 ttgttacaat gccacttggc tatgtaacac atggcttaaa tttggaagaa gctgctcggt 4620 atatgagatc tctcaaagtg ccagctacag tttctgtttc ttcacctgat gctgttacag 4680 cgtataatgg ttatcttact tcttcttcta aaacacctga agaacatttt attgaaacca 4740 tctcacttgc tggttcctat aaagattggt cctattctgg acaatctaca caactaggta 4800 tagaatttct taagagaggt gataaaagtg tatattacac tagtaatcct accacattcc 4860 acctagatgg tgaagttatc acctttgaca atcttaagac acttctttct ttgagagaag 4920 tgaggactat taaggtgttt acaacagtag acaacattaa cctccacacg caagttgtgg 4980 acatgtcaat gacatatgga caacagtttg gtccaactta tttggatgga gctgatgtta 5040 ctaaaataaa acctcataat tcacatgaag gtaaaacatt ttatgtttta cctaatgatg 5100 acactctacg tgttgaggct tttgagtact accacacaac tgatcctagt tttctgggta 5160 ggtacatgtc agcattaaat cacactaaaa agtggaaata cccacaagtt aatggtttaa 5220 cttctattaa atgggcagat aacaactgtt atcttgccac tgcattgtta acactccaac 5280 aaatagagtt gaagtttaat ccacctgctc tacaagatgc ttattacaga gcaagggctg 5340 gtgaagctgc taacttttgt gcacttatct tagcctactg taataagaca gtaggtgagt 5400 taggtgatgt tagagaaaca atgagttact tgtttcaaca tgccaattta gattcttgca 5460 aaagagtctt gaacgtggtg tgtaaaactt gtggacaaca gcagacaacc cttaagggtg 5520 tagaagctgt tatgtacatg ggcacacttt cttatgaaca atttaagaaa ggtgttcaga 5580 taccttgtac gtgtggtaaa caagctacaa aatatctagt acaacaggag tcaccttttg 5640 ttatgatgtc agcaccacct gctcagtatg aacttaagca tggtacattt acttgtgcta 5700 gtgagtacac tggtaattac cagtgtggtc actataaaca tataacttct aaagaaactt 5760 tgtattgcat agacggtgct ttacttacaa agtcctcaga atacaaaggt cctattacgg 5820 atgttttcta caaagaaaac agttacacaa caaccataaa accagttact tataaattgg 5880 atggtgttgt ttgtacagaa attgacccta agttggacaa ttattataag aaagacaatt 5940 cttatttcac agagcaacca attgatcttg taccaaacca accatatcca aacgcaagct 6000 tcgataattt taagtttgta tgtgataata tcaaatttgc tgatgattta aaccagttaa 6060 ctggttataa gaaacctgct tcaagagagc ttaaagttac atttttccct gacttaaatg 6120 gtgatgtggt ggctattgat tataaacact acacaccctc ttttaagaaa ggagctaaat 6180 tgttacataa acctattgtt tggcatgtta acaatgcaac taataaagcc acgtataaac 6240 caaatacctg gtgtatacgt tgtctttgga gcacaaaacc agttgaaaca tcaaattcgt 6300 ttgatgtact gaagtcagag gacgcgcagg gaatggataa tcttgcctgc gaagatctaa 6360 aaccagtctc tgaagaagta gtggaaaatc ctaccataca gaaagacgtt cttgagtgta 6420 atgtgaaaac taccgaagtt gtaggagaca ttatacttaa accagcaaat aatagtttaa 6480 aaattacaga agaggttggc cacacagatc taatggctgc ttatgtagac aattctagtc 6540 ttactattaa gaaacctaat gaattatcta gagtattagg tttgaaaacc cttgctactc 6600 atggtttagc tgctgttaat agtgtccctt gggatactat agctaattat gctaagcctt 6660 ttcttaacaa agttgttagt acaactacta acatagttac acggtgttta aaccgtgttt 6720 gtactaatta tatgccttat ttctttactt tattgctaca attgtgtact tttactagaa 6780 gtacaaattc tagaattaaa gcatctatgc cgactactat agcaaagaat actgttaaga 6840 gtgtcggtaa attttgtcta gaggcttcat ttaattattt gaagtcacct aatttttcta 6900 aactgataaa tattataatt tggtttttac tattaagtgt ttgcctaggt tctttaatct 6960 actcaaccgc tgctttaggt gttttaatgt ctaatttagg catgccttct tactgtactg 7020 gttacagaga aggctatttg aactctacta atgtcactat tgcaacctac tgtactggtt 7080 ctataccttg tagtgtttgt cttagtggtt tagattcttt agacacctat ccttctttag 7140 aaactataca aattaccatt tcatctttta aatgggattt aactgctttt ggcttagttg 7200 cagagtggtt tttggcatat attcttttca ctaggttttt ctatgtactt ggattggctg 7260 caatcatgca attgtttttc agctattttg cagtacattt tattagtaat tcttggctta 7320 tgtggttaat aattaatctt gtacaaatgg ccccgatttc agctatggtt agaatgtaca 7380 tcttctttgc atcattttat tatgtatgga aaagttatgt gcatgttgta gacggttgta 7440 attcatcaac ttgtatgatg tgttacaaac gtaatagagc aacaagagtc gaatgtacaa 7500 ctattgttaa tggtgttaga aggtcctttt atgtctatgc taatggaggt aaaggctttt 7560 gcaaactaca caattggaat tgtgttaatt gtgatacatt ctgtgctggt agtacattta 7620 ttagtgatga agttgcgaga gacttgtcac tacagtttaa aagaccaata aatcctactg 7680 accagtcttc ttacatcgtt gatagtgtta cagtgaagaa tggttccatc catctttact 7740 ttgataaagc tggtcaaaag acttatgaaa gacattctct ctctcatttt gttaacttag 7800 acaacctgag agctaataac actaaaggtt cattgcctat taatgttata gtttttgatg 7860 gtaaatcaaa atgtgaagaa tcatctgcaa aatcagcgtc tgtttactac agtcagctta 7920 tgtgtcaacc tatactgtta ctagatcagg cattagtgtc tgatgttggt gatagtgcgg 7980 aagttgcagt taaaatgttt gatgcttacg ttaatacgtt ttcatcaact tttaacgtac 8040 caatggaaaa actcaaaaca ctagttgcaa ctgcagaagc tgaacttgca aagaatgtgt 8100 ccttagacaa tgtcttatct acttttattt cagcagctcg gcaagggttt gttgattcag 8160 atgtagaaac taaagatgtt gttgaatgtc ttaaattgtc acatcaatct gacatagaag 8220 ttactggcga tagttgtaat aactatatgc tcacctataa caaagttgaa aacatgacac 8280 cccgtgacct tggtgcttgt attgactgta gtgcgcgtca tattaatgcg caggtagcaa 8340 aaagtcacaa cattgctttg atatggaacg ttaaagattt catgtcattg tctgaacaac 8400 tacgaaaaca aatacgtagt gctgctaaaa agaataactt accttttaag ttgacatgtg 8460 caactactag acaagttgtt aatgttgtaa caacaaagat agcacttaag ggtggtaaaa 8520 ttgttaataa ttggttgaag cagttaatta aagttacact tgtgttcctt tttgttgctg 8580 ctattttcta tttaataaca cctgttcatg tcatgtctaa acatactgac ttttcaagtg 8640 aaatcatagg atacaaggct attgatggtg gtgtcactcg tgacatagca tctacagata 8700 cttgttttgc taacaaacat gctgattttg acacatggtt tagccagcgt ggtggtagtt 8760 atactaatga caaagcttgc ccattgattg ctgcagtcat aacaagagaa gtgggttttg 8820 tcgtgcctgg tttgcctggc acgatattac gcacaactaa tggtgacttt ttgcatttct 8880 tacctagagt ttttagtgca gttggtaata tctgttacac accatcaaaa cttatagagt 8940 acactgactt tgcaacatca gcttgtgttt tggctgctga atgtacaatt tttaaagatg 9000 cttctggtaa gccagtacca tattgttatg ataccaatgt actagaaggt tctgttgctt 9060 atgaaagttt acgccctgac acacgttatg tgctcatgga tggctctatt attcaatttc 9120 ctaacaccta ccttgaaggt tctgttagag tggtaacaac ttttgattct gagtactgta 9180 ggcacggcac ttgtgaaaga tcagaagctg gtgtttgtgt atctactagt ggtagatggg 9240 tacttaacaa tgattattac agatctttac caggagtttt ctgtggtgta gatgctgtaa 9300 atttacttac taatatgttt acaccactaa ttcaacctat tggtgctttg gacatatcag 9360 catctatagt agctggtggt attgtagcta tcgtagtaac atgccttgcc tactatttta 9420 tgaggtttag aagagctttt ggtgaataca gtcatgtagt tgcctttaat actttactat 9480 tccttatgtc attcactgta ctctgtttaa caccagttta ctcattctta cctggtgttt 9540 attctgttat ttacttgtac ttgacatttt atcttactaa tgatgtttct tttttagcac 9600 atattcagtg gatggttatg ttcacacctt tagtaccttt ctggataaca attgcttata 9660 tcatttgtat ttccacaaag catttctatt ggttctttag taattaccta aagagacgtg 9720 tagtctttaa tggtgtttcc tttagtactt ttgaagaagc tgcgctgtgc acctttttgt 9780 taaataaaga aatgtatcta aagttgcgta gtgatgtgct attacctctt acgcaatata 9840 atagatactt agctctttat aataagtaca agtattttag tggagcaatg gatacaacta 9900 gctacagaga agctgcttgt tgtcatctcg caaaggctct caatgacttc agtaactcag 9960 gttctgatgt tctttaccaa ccaccacaaa cctctatcac ctcagctgtt ttgcagagtg 10020 gttttagaaa aatggcattc ccatctggta aagttgaggg ttgtatggta caagtaactt 10080 gtggtacaac tacacttaac ggtctttggc ttgatgacgt agtttactgt ccaagacatg 10140 tgatctgcac ctctgaagac atgcttaacc ctaattatga agatttactc attcgtaagt 10200 ctaatcataa tttcttggta caggctggta atgttcaact cagggttatt ggacattcta 10260 tgcaaaattg tgtacttaag cttaaggttg atacagccaa tcctaagaca cctaagtata 10320 agtttgttcg cattcaacca ggacagactt tttcagtgtt agcttgttac aatggttcac 10380 catctggtgt ttaccaatgt gctatgaggc ccaatttcac tattaagggt tcattcctta 10440 atggttcatg tggtagtgtt ggttttaaca tagattatga ctgtgtctct ttttgttaca 10500 tgcaccatat ggaattacca actggagttc atgctggcac agacttagaa ggtaactttt 10560 atggaccttt tgttgacagg caaacagcac aagcagctgg tacggacaca actattacag 10620 ttaatgtttt agcttggttg tacgctgctg ttataaatgg agacaggtgg tttctcaatc 10680 gatttaccac aactcttaat gactttaacc ttgtggctat gaagtacaat tatgaacctc 10740 taacacaaga ccatgttgac atactaggac ctctttctgc tcaaactgga attgccgttt 10800 tagatatgtg tgcttcatta aaagaattac tgcaaaatgg tatgaatgga cgtaccatat 10860 tgggtagtgc tttattagaa gatgaattta caccttttga tgttgttaga caatgctcag 10920 gtgttacttt ccaaagtgca gtgaaaagaa caatcaaggg tacacaccac tggttgttac 10980 tcacaatttt gacttcactt ttagttttag tccagagtac tcaatggtct ttgttctttt 11040 ttttgtatga aaatgccttt ttaccttttg ctatgggtat tattgctatg tctgcttttg 11100 caatgatgtt tgtcaaacat aagcatgcat ttctctgttt gtttttgtta ccttctcttg 11160 ccactgtagc ttattttaat atggtctata tgcctgctag ttgggtgatg cgtattatga 11220 catggttgga tatggttgat actagtttgt ctggttttaa gctaaaagac tgtgttatgt 11280 atgcatcagc tgtagtgtta ctaatcctta tgacagcaag aactgtgtat gatgatggtg 11340 ctaggagagt gtggacactt atgaatgtct tgacactcgt ttataaagtt tattatggta 11400 atgctttaga tcaagccatt tccatgtggg ctcttataat ctctgttact tctaactact 11460 caggtgtagt tacaactgtc atgtttttgg ccagaggtat tgtttttatg tgtgttgagt 11520 attgccctat tttcttcata actggtaata cacttcagtg tataatgcta gtttattgtt 11580 tcttaggcta tttttgtact tgttactttg gcctcttttg tttactcaac cgctacttta 11640 gactgactct tggtgtttat gattacttag tttctacaca ggagtttaga tatatgaatt 11700 cacagggact actcccaccc aagaatagca tagatgcctt caaactcaac attaaattgt 11760 tgggtgttgg tggcaaacct tgtatcaaag tagccactgt acagtctaaa atgtcagatg 11820 taaagtgcac atcagtagtc ttactctcag ttttgcaaca actcagagta gaatcatcat 11880 ctaaattgtg ggctcaatgt gtccagttac acaatgacat tctcttagct aaagatacta 11940 ctgaagcctt tgaaaaaatg gtttcactac tttctgtttt gctttccatg cagggtgctg 12000 tagacataaa caagctttgt gaagaaatgc tggacaacag ggcaacctta caagctatag 12060 cttcagagtt tagttccctt ccatcatatg cagcttttgc tactgctcaa gaagcttatg 12120 agcaggctgt tgctaatggt gattctgaag ttgttcttaa aaagttgaag aagtctttga 12180 atgtggctaa atctgaattt gaccgtgatg cagccatgca acgtaagttg gaaaagatgg 12240 ctgatcaagc tatgacccaa atgtataaac aggctagatc tgaggacaag agggcaaaag 12300 ttactagtgc tatgcagaca atgcttttca ctatgcttag aaagttggat aatgatgcac 12360 tcaacaacat tatcaacaat gcaagagatg gttgtgttcc cttgaacata atacctctta 12420 caacagcagc caaactaatg gttgtcatac cagactataa cacatataaa aatacgtgtg 12480 atggtacaac atttacttat gcatcagcat tgtgggaaat ccaacaggtt gtagatgcag 12540 atagtaaaat tgttcaactt agtgaaatta gtatggacaa ttcacctaat ttagcatggc 12600 ctcttattgt aacagcttta agggccaatt ctgctgtcaa attacagaat aatgagctta 12660 gtcctgttgc actacgacag atgtcttgtg ctgccggtac tacacaaact gcttgcactg 12720 atgacaatgc gttagcttac tacaacacaa caaagggagg taggtttgta cttgcactgt 12780 tatccgattt acaggatttg aaatgggcta gattccctaa gagtgatgga actggtactg 12840 tctatacaga actggaacca ccttgtaggt ttgttacaga cacacctaaa ggtcctaaag 12900 tgaagtattt atactttatt aaaggattaa acaacctaaa tagaggtatg gtacttggta 12960 gtttagctgc cacagtacgt ctacaagctg gtaatgcaac agaagtgcct gccaattcaa 13020 ctgtattatc tttctgtgct tttgctgtag atgctgctaa agcttacaaa gattatctag 13080 ctagtggggg acaaccaatc actaattgtg ttaagatgtt gtgtacacac actggtactg 13140 gtcaggcaat aacagttaca ccggaagcca atatggatca agaatccttt ggtggtgcat 13200 cgtgttgtct gtactgccgt tgccacatag atcatccaaa tcctaaagga ttttgtgact 13260 taaaaggtaa gtatgtacaa atacctacaa cttgtgctaa tgaccctgtg ggttttacac 13320 ttaaaaacac agtctgtacc gtctgcggta tgtggaaagg ttatggctgt agttgtgatc 13380 aactccgcga acccatgctt cagtcagctg atgcacaatc gtttttaaac gggtttgcgg 13440 tgtaagtgca gcccgtctta caccgtgcgg cacaggcact agtactgatg tcgtatacag 13500 ggcttttgac atctacaatg ataaagtagc tggttttgct aaattcctaa aaactaattg 13560 ttgtcgcttc caagaaaagg acgaagatga caatttaatt gattcttact ttgtagttaa 13620 gagacacact ttctctaact accaacatga agaaacaatt tataatttac ttaaggattg 13680 tccagctgtt gctaaacatg acttctttaa gtttagaata gacggtgaca tggtaccaca 13740 tatatcacgt caacgtctta ctaaatacac aatggcagac ctcgtctatg ctttaaggca 13800 ttttgatgaa ggtaattgtg acacattaaa agaaatactt gtcacataca attgttgtga 13860 tgatgattat ttcaataaaa aggactggta tgattttgta gaaaacccag atatattacg 13920 cgtatacgcc aacttaggtg aacgtgtacg ccaagctttg ttaaaaacag tacaattctg 13980 tgatgccatg cgaaatgctg gtattgttgg tgtactgaca ttagataatc aagatctcaa 14040 tggtaactgg tatgatttcg gtgatttcat acaaaccacg ccaggtagtg gagttcctgt 14100 tgtagattct tattattcat tgttaatgcc tatattaacc ttgaccaggg ctttaactgc 14160 agagtcacat gttgacactg acttaacaaa gccttacatt aagtgggatt tgttaaaata 14220 tgacttcacg gaagagaggt taaaactctt tgaccgttat tttaaatatt gggatcagac 14280 ataccaccca aattgtgtta actgtttgga tgacagatgc attctgcatt gtgcaaactt 14340 taatgtttta ttctctacag tgttcccact tacaagtttt ggaccactag tgagaaaaat 14400 atttgttgat ggtgttccat ttgtagtttc aactggatac cacttcagag agctaggtgt 14460 tgtacataat caggatgtaa acttacatag ctctagactt agttttaagg aattacttgt 14520 gtatgctgct gaccctgcta tgcacgctgc ttctggtaat ctattactag ataaacgcac 14580 tacgtgcttt tcagtagctg cacttactaa caatgttgct tttcaaactg tcaaacccgg 14640 taattttaac aaagacttct atgactttgc tgtgtctaag ggtttcttta aggaaggaag 14700 ttctgttgaa ttaaaacact tcttctttgc tcaggatggt aatgctgcta tcagcgatta 14760 tgactactat cgttataatc taccaacaat gtgtgatatc agacaactac tatttgtagt 14820 tgaagttgtt gataagtact ttgattgtta cgatggtggc tgtattaatg ctaaccaagt 14880 catcgtcaac aacctagaca aatcagctgg ttttccattt aataaatggg gtaaggctag 14940 actttattat gattcaatga gttatgagga tcaagatgca cttttcgcat atacaaaacg 15000 taatgtcatc cctactataa ctcaaatgaa tcttaagtat gccattagtg caaagaatag 15060 agctcgcacc gtagctggtg tctctatctg tagtactatg accaatagac agtttcatca 15120 aaaattattg aaatcaatag ccgccactag aggagctact gtagtaattg gaacaagcaa 15180 attctatggt ggttggcaca acatgttaaa aactgtttat agtgatgtag aaaaccctca 15240 ccttatgggt tgggattatc ctaaatgtga tagagccatg cctaacatgc ttagaattat 15300 ggcctcactt gttcttgctc gcaaacatac aacgtgttgt agcttgtcac accgtttcta 15360 tagattagct aatgagtgtg ctcaagtatt gagtgaaatg gtcatgtgtg gcggttcact 15420 atatgttaaa ccaggtggaa cctcatcagg agatgccaca actgcttatg ctaatagtgt 15480 ttttaacatt tgtcaagctg tcacggccaa tgttaatgca cttttatcta ctgatggtaa 15540 caaaattgcc gataagtatg tccgcaattt acaacacaga ctttatgagt gtctctatag 15600 aaatagagat gttgacacag actttgtgaa tgagttttac gcatatttgc gtaaacattt 15660 ctcaatgatg atactctctg acgatgctgt tgtgtgtttc aatagcactt atgcatctca 15720 aggtctagtg gctagcataa agaactttaa gtcagttctt tattatcaaa acaatgtttt 15780 tatgtctgaa gcaaaatgtt ggactgagac tgaccttact aaaggacctc atgaattttg 15840 ctctcaacat acaatgctag ttaaacaggg tgatgattat gtgtaccttc cttacccaga 15900 tccatcaaga atcctagggg ccggctgttt tgtagatgat atcgtaaaaa cagatggtac 15960 acttatgatt gaacggttcg tgtctttagc tatagatgct tacccactta ctaaacatcc 16020 taatcaggag tatgctgatg tctttcattt gtacttacaa tacataagaa agctacatga 16080 tgagttaaca ggacacatgt tagacatgta ttctgttatg cttactaatg ataacacttc 16140 aaggtattgg gaacctgagt tttatgaggc tatgtacaca ccgcatacag tcttacaggc 16200 tgttggggct tgtgttcttt gcaattcaca gacttcatta agatgtggtg cttgcatacg 16260 tagaccattc ttatgttgta aatgctgtta cgaccatgtc atatcaacat cacataaatt 16320 agtcttgtct gttaatccgt atgtttgcaa tgctccaggt tgtgatgtca cagatgtgac 16380 tcaactttac ttaggaggta tgagctatta ttgtaaatca cataaaccac ccattagttt 16440 tccattgtgt gctaatggac aagtttttgg tttatataaa aatacatgtg ttggtagcga 16500 taatgttact gactttaatg caattgcaac atgtgactgg acaaatgctg gtgattacat 16560 tttagctaac acctgtactg aaagactcaa gctttttgca gcagaaacgc tcaaagctac 16620 tgaggagaca tttaaactgt cttatggtat tgctactgta cgtgaagtgc tgtctgacag 16680 agaattacat ctttcatggg aagttggtaa acctagacca ccacttaacc gaaattatgt 16740 ctttactggt tatcgtgtaa ctaaaaacag taaagtacaa ataggagagt acacctttga 16800 aaaaggtgac tatggtgatg ctgttgttta ccgaggtaca acaacttaca aattaaatgt 16860 tggtgattat tttgtgctga catcacatac agtaatgcca ttaagtgcac ctacactagt 16920 gccacaagag cactatgtta gaattactgg cttataccca acactcaata tctcatatga 16980 gttttctagc aatgttgcaa attatcaaaa ggttggtatg caaaagtatt ctacactcca 17040 gggaccacct ggtactggta agagtcattt tgctattggc ctagctctct actacccttc 17100 tgctcgcata gtgtatacag cttgctctca tgccgctgtt gatgcactat gtgagaaggc 17160 attaaaatat ttgcctatag ataaatgtag tagaattata cctgcacgtg ctcgtgtaga 17220 gtgttttgat aaattcaaag tgaattcaac attagaacag tatgtctttt gtactgtaaa 17280 tgcattgcct gagacgacag cagatatagt tgtctttgat gaaatttcaa tggccacaaa 17340 ttatgatttg agtgttgtca atgccagatt acgtgctaag cactatgtgt acattggcga 17400 ccctgctcaa ttacctgcac cacgcacatt gctaactaag ggcacactag aaccagaata 17460 tttcaattca gtgtgtagac ttatgaaaac tataggtcca gacatgttcc tcggaacttg 17520 tcggcgttgt cctgctgaaa ttgttgacac tgtgagtgct ttggtttatg ataataagct 17580 taaagcacat aaagacaaat cagctcaatg ctttaaaatg ttttataagg gtgttatcac 17640 gcatgatgtt tcatctgcaa ttaacaggcc acaaataggc gtggtaagag aattccttac 17700 acgtaaccct gcttggagaa aagctgtctt tatttcacct tataattcac agaatgctgt 17760 agcctcaaag attttgggac taccaactca aactgttgat tcatcacagg gctcagaata 17820 tgactatgtc atattcactc aaaccactga aacagctcac tcttgtaatg taaacagatt 17880 taatgttgct attaccagag caaaagtagg catactttgc ataatgtctg atagagacct 17940 ttatgacaag ttgcaattta caagtcttga aattccacgt aggaatgtgg caactttaca 18000 agctgaaaat gtaacaggac tctttaaaga ttgtagtaag gtaatcactg ggttacatcc 18060 tacacaggca cctacacacc tcagtgttga cactaaattc aaaactgaag gtttatgtgt 18120 tgacatacct ggcataccta aggacatgac ctatagaaga ctcatctcta tgatgggttt 18180 taaaatgaat tatcaagtta atggttaccc taacatgttt atcacccgcg aagaagctat 18240 aagacatgta cgtgcatgga ttggcttcga tgtcgagggg tgtcatgcta ctagagaagc 18300 tgttggtacc aatttacctt tacagctagg tttttctaca ggtgttaacc tagttgctgt 18360 acctacaggt tatgttgata cacctaataa tacagatttt tccagagtta gtgctaaacc 18420 accgcctgga gatcaattta aacacctcat accacttatg tacaaaggac ttccttggaa 18480 tgtagtgcgt ataaagattg tacaaatgtt aagtgacaca cttaaaaatc tctctgacag 18540 agtcgtattt gtcttatggg cacatggctt tgagttgaca tctatgaagt attttgtgaa 18600 aataggacct gagcgcacct gttgtctatg tgatagacgt gccacatgct tttccactgc 18660 ttcagacact tatgcctgtt ggcatcattc tattggattt gattacgtct ataatccgtt 18720 tatgattgat gttcaacaat ggggttttac aggtaaccta caaagcaacc atgatctgta 18780 ttgtcaagtc catggtaatg cacatgtagc tagttgtgat gcaatcatga ctaggtgtct 18840 agctgtccac gagtgctttg ttaagcgtgt tgactggact attgaatatc ctataattgg 18900 tgatgaactg aagattaatg cggcttgtag aaaggttcaa cacatggttg ttaaagctgc 18960 attattagca gacaaattcc cagttcttca cgacattggt aaccctaaag ctattaagtg 19020 tgtacctcaa gctgatgtag aatggaagtt ctatgatgca cagccttgta gtgacaaagc 19080 ttataaaata gaagaattat tctattctta tgccacacat tctgacaaat tcacagatgg 19140 tgtatgccta ttttggaatt gcaatgtcga tagatatcct gctaattcca ttgtttgtag 19200 atttgacact agagtgctat ctaaccttaa cttgcctggt tgtgatggtg gcagtttgta 19260 tgtaaataaa catgcattcc acacaccagc ttttgataaa agtgcttttg ttaatttaaa 19320 acaattacca tttttctatt actctgacag tccatgtgag tctcatggaa aacaagtagt 19380 gtcagatata gattatgtac cactaaagtc tgctacgtgt ataacacgtt gcaatttagg 19440 tggtgctgtc tgtagacatc atgctaatga gtacagattg tatctcgatg cttataacat 19500 gatgatctca gctggcttta gcttgtgggt ttacaaacaa tttgatactt ataacctctg 19560 gaacactttt acaagacttc agagtttaga aaatgtggct tttaatgttg taaataaggg 19620 acactttgat ggacaacagg gtgaagtacc agtttctatc attaataaca ctgtttacac 19680 aaaagttgat ggtgttgatg tagaattgtt tgaaaataaa acaacattac ctgttaatgt 19740 agcatttgag ctttgggcta agcgcaacat taaaccagta ccagaggtga aaatactcaa 19800 taatttgggt gtggacattg ctgctaatac tgtgatctgg gactacaaaa gagatgctcc 19860 agcacatata tctactattg gtgtttgttc tatgactgac atagccaaga aaccaactga 19920 aacgatttgt gcaccactca ctgtcttttt tgatggtaga gttgatggtc aagtagactt 19980 atttagaaat gcccgtaatg gtgttcttat tacagaaggt agtgttaaag gtttacaacc 20040 atctgtaggt cccaaacaag ctagtcttaa tggagtcaca ttaattggag aagccgtaaa 20100 aacacagttc aattattata agaaagttga tggtgttgtc caacaattac ctgaaactta 20160 ctttactcag agtagaaatt tacaagaatt taaacccagg agtcaaatgg aaattgattt 20220 cttagaatta gctatggatg aattcattga acggtataaa ttagaaggct atgccttcga 20280 acatatcgtt tatggagatt ttagtcatag tcagttaggt ggtttacatc tactgattgg 20340 actagctaaa cgttttaagg aatcaccttt tgaattagaa gattttattc ctatggacag 20400 tacagttaaa aactatttca taacagatgc gcaaacaggt tcatctaagt gtgtgtgttc 20460 tgttattgat ttattacttg atgattttgt tgaaataata aaatcccaag atttatctgt 20520 agtttctaag gttgtcaaag tgactattga ctatacagaa atttcattta tgctttggtg 20580 taaagatggc catgtagaaa cattttaccc aaaattacaa tctagtcaag cgtggcaacc 20640 gggtgttgct atgcctaatc tttacaaaat gcaaagaatg ctattagaaa agtgtgacct 20700 tcaaaattat ggtgatagtg caacattacc taaaggcata atgatgaatg tcgcaaaata 20760 tactcaactg tgtcaatatt taaacacatt aacattagct gtaccctata atatgagagt 20820 tatacatttt ggtgctggtt ctgataaagg agttgcacca ggtacagctg ttttaagaca 20880 gtggttgcct acgggtacgc tgcttgtcga ttcagatctt aatgactttg tctctgatgc 20940 agattcaact ttgattggtg attgtgcaac tgtacataca gctaataaat gggatctcat 21000 tattagtgat atgtacgacc ctaagactaa aaatgttaca aaagaaaatg actctaaaga 21060 gggttttttc acttacattt gtgggtttat acaacaaaag ctagctcttg gaggttccgt 21120 ggctataaag ataacagaac attcttggaa tgctgatctt tataagctca tgggacactt 21180 cgcatggtgg acagcctttg ttactaatgt gaatgcgtca tcatctgaag catttttaat 21240 tggatgtaat tatcttggca aaccacgcga acaaatagat ggttatgtca tgcatgcaaa 21300 ttacatattt tggaggaata caaatccaat tcagttgtct tcctattctt tatttgacat 21360 gagtaaattt ccccttaaat taaggggtac tgctgttatg tctttaaaag aaggtcaaat 21420 caatgatatg attttatctc ttcttagtaa aggtagactt ataattagag aaaacaacag 21480 agttgttatt tctagtgatg ttcttgttaa caactaaacg aacaatgttt gtttttcttg 21540 ttttattgcc actagtctct attcagtgtg ttaatcttac aaccagaact caattacccc 21600 ctgcatacac taattctttc acacgtggtg tttattaccc tgacaaagtt ttcagatcct 21660 cagttttaca ttcaactcag gacttgttct tacctttctt ttccaatgtt acttggttcc 21720 atgctataca tgtctctggg accaatggta ctaagaggtt tgataaccct gtcctaccat 21780 ttaatgatgg tgtttatttt gcttccactg agaagtctaa cataataaga ggctggattt 21840 ttggtactac tttagattcg aagacccagt ccctacttat tgttaataac gctactaatg 21900 ttgttattaa agtctgtgaa tttcaatttt gtaatgatcc atttttgggt gtttattacc 21960 acaaaaacaa caaaagttgt atggaaagtg agttcagagt ttattctagt gcgaataatt 22020 gcacttttga atatgtctct cagccttttc ttatggacct tgaaggaaaa cagggtaatt 22080 tcaaaaatct tagggaattt gtgtttaaga atattgatgg ttattttaaa atatattcta 22140 agcacacgcc tattaattta gtgcgtgatc tccctcaggg tttttcggct ttagaaccat 22200 tggtagattt gccaataggt attaacatca ctaggtttca aactttactt gctttacata 22260 gaagttattt gactcctggt gattcttctt caggttggac agctggtgct gcagcttatt 22320 atgtgggtta tcttcaacct aggacttttc tattaaaata taatgaaaat ggaaccatta 22380 cagatgctgt agactgtgca cttgaccctc tctcagaaac aaagtgtacg ttgaaatcct 22440 tcactgtaga aaaaggaatc tatcaaactt ctaactttag agtccaacca acagaatcta 22500 ttgttagatt tcctaatatt acaaacttgt gcccttttgg tgaagttttt aacgccacca 22560 gatttgcatc tgtttatgct tggaacagga agagaatcag caactgtgtt gctgattatt 22620 ctgtcctata taattccgca tcattttcca cttttaagtg ttatggagtg tctcctacta 22680 aattaaatga tctctgcttt actaatgtct atgcagattc atttgtaatt agaggtgatg 22740 aagtcagaca aatcgctcca gggcaaactg gaaagattgc tgattataat tataaattac 22800 cagatgattt tacaggctgc gttatagctt ggaattctaa caatcttgat tctaaggttg 22860 gtggtaatta taattaccgg tatagattgt ttaggaagtc taatctcaaa ccttttgaga 22920 gagatatttc aactgaaatc tatcaggccg gtagcacacc ttgtaatggt gttgaaggtt 22980 ttaattgtta ctttccttta caatcatatg gtttccaacc cactaatggt gttggttacc 23040 aaccatacag agtagtagta ctttcttttg aacttctaca tgcaccagca actgtttgtg 23100 gacctaaaaa gtctactaat ttggttaaaa acaaatgtgt caatttcaac ttcaatggtt 23160 taacaggcac aggtgttctt actgagtcta acaaaaagtt tctgcctttc caacaatttg 23220 gcagagacat tgctgacact actgatgctg tccgtgatcc acagacactt gagattcttg 23280 acattacacc atgttctttt ggtggtgtca gtgttataac accaggaaca aatacttcta 23340 accaggttgc tgttctttat cagggtgtta actgcacaga agtccctgtt gctattcatg 23400 cagatcaact tactcctact tggcgtgttt attctacagg ttctaatgtt tttcaaacac 23460 gtgcaggctg tttaataggg gctgaacatg tcaacaactc atatgagtgt gacataccca 23520 ttggtgcagg tatatgcgct agttatcaga ctcagactaa ttctcctcgg cgggcacgta 23580 gtgtagctag tcaatccatc attgcctaca ctatgtcact tggtgcagaa aattcagttg 23640 cttactctaa taactctatt gccataccca caaattttac tattagtgtt accacagaaa 23700 ttctaccagt gtctatgacc aagacatcag tagattgtac aatgtacatt tgtggtgatt 23760 caactgaatg cagcaatctt ttgttgcaat atggcagttt ttgtacacaa ttaaaccgtg 23820 ctttaactgg aatagctgtt gaacaagaca aaaacaccca agaagttttt gcacaagtca 23880 aacaaattta caaaacacca ccaattaaag attttggtgg ttttaatttt tcacaaatat 23940 taccagatcc atcaaaacca agcaagaggt catttattga agatctactt ttcaacaaag 24000 tgacacttgc agatgctggc ttcatcaaac aatatggtga ttgccttggt gatattgctg 24060 ctagagacct catttgtgca caaaagttta acggccttac tgttttgcca cctttgctca 24120 cagatgaaat gattgctcaa tacacttctg cactgttagc gggtacaatc acttctggtt 24180 ggacctttgg tgcaggtgct gcattacaaa taccatttgc tatgcaaatg gcttataggt 24240 ttaatggtat tggagttaca cagaatgttc tctatgagaa ccaaaaattg attgccaacc 24300 aatttaatag cgctattggc aaaattcaag actcactttc ttccacagca agtgcacttg 24360 gaaaacttca agatgtggtc aaccaaaatg cacaagcttt aaacacgctt gttaaacaac 24420 ttagctccaa ttttggtgca atttcaagtg ttttaaatga tatcctttca cgtcttgaca 24480 aagttgaggc tgaagtgcaa attgataggt tgatcacagg cagacttcaa agtttgcaga 24540 catatgtgac tcaacaatta attagagctg cagaaatcag agcttctgct aatcttgctg 24600 ctactaaaat gtcagagtgt gtacttggac aatcaaaaag agttgatttt tgtggaaagg 24660 gctatcatct tatgtccttc cctcagtcag cacctcatgg tgtagtcttc ttgcatgtga 24720 cttatgtccc tgcacaagaa aagaacttca caactgctcc tgccatttgt catgatggaa 24780 aagcacactt tcctcgtgaa ggtgtctttg tttcaaatgg cacacactgg tttgtaacac 24840 aaaggaattt ttatgaacca caaatcatta ctacagacaa cacatttgtg tctggtaact 24900 gtgatgttgt aataggaatt gtcaacaaca cagtttatga tcctttgcaa cctgaattag 24960 actcattcaa ggaggagtta gataaatatt ttaagaatca tacatcacca gatgttgatt 25020 taggtgacat ctctggcatt aatgcttcag ttgtaaacat tcaaaaagaa attgaccgcc 25080 tcaatgaggt tgccaagaat ttaaatgaat ctctcatcga tctccaagaa cttggaaagt 25140 atgagcagta tataaaatgg ccatggtaca tttggctagg ttttatagct ggcttgattg 25200 ccatagtaat ggtgacaatt atgctttgct gtatgaccag ttgctgtagt tgtctcaagg 25260 gctgttgttc ttgtggatcc tgctgcaaat ttgatgaaga cgactctgag ccagtgctca 25320 aaggagtcaa attacattac acataaacga acttatggat ttgtttatga gaatcttcac 25380 aattggaact gtaactttga agcaaggtga aatcaaggat gctactcctt cagattttgt 25440 tcgcgctact gcaacgatac cgatacaagc ctcactccct ttcggatggc ttattgttgg 25500 cgttgcactt cttgctgttt ttcatagcgc ttccaaaatc ataaccctca aaaagagatg 25560 gcaactagca ctctccaagg gtgttcactt tgtttgcaac ttgctgttgt tgtttgtaac 25620 agtttactca caccttttgc tcgttgctgt tggccttgaa gccccttttc tctatcttta 25680 tgctttagtc tacttcttgc agagtataaa ctttgtaaga ataataatga ggctttggct 25740 ttgctggaaa tgccgttcca aaaacccatt actttatgat gccaactatt ttctttgctg 25800 gcatactaat tgttacgact attgtatacc ttacaatagt gtaacttctt caattgtcat 25860 tacttcaggt gatggcacaa caagtcctat ttctgaacat gactaccaga ttggtggtta 25920 tactgaaaaa tgggaatctg gagtaaaaga ctgtgttgta ttacacagtt acttcacttc 25980 agactattac cagctgtact caactcaatt gagtacagac actggtgttg aacatgttac 26040 cttcttcatc tacaataaaa ttgttgatga gcctgaagaa catgtccaaa ttcacacaat 26100 cgacggttca tccggagttg ttaatccagt aatggaacca atttatgatg aaccgacgac 26160 gactactagc gtgcctttgt aagcacaagc tgatgagtac gaacttatgt actcattcgt 26220 ttcggaagag acaggtacgt taatagttaa tagcgtactt ctttttcttg ctttcgtggt 26280 attcttgcta gttacactag ccatccttac tgcgcttcga ttgtgtgcgt actgctgcaa 26340 tattgttaac gtgagtcttg taaaaccttc tttttacgtt tactctcgtg ttaaaaatct 26400 gaattcttct agagttcctg atcttctggt ctaaacgaac taaatattat attagttttt 26460 ctgtttggaa ctttaatttt agccatggca gattccaacg gtactattac cgttgaagag 26520 cttaaaaagc tccttgaaca atggaaccta gtaataggtt tcctattcct tacatggatt 26580 tgtcttctac aatttgccta tgccaacagg aataggtttt tgtatataat taagttaatt 26640 tttctctggc tgttatggcc agtaacttta gcttgttttg tgcttgctgc tgtttacaga 26700 ataaattgga tcaccggtgg aattgctatc gcaatggctt gtcttgtagg cttgatgtgg 26760 ctcagctact tcattgcttc tttcagactg tttgcgcgta cgcgttccat gtggtcattc 26820 aatccagaaa ctaacattct tctcaacgtg ccactccatg gcactattct gaccagaccg 26880 cttctagaaa gtgaactcgt aatcggagct gtgatccttc gtggacatct tcgtattgct 26940 ggacaccatc taggacgctg tgacatcaag gacctgccta aagaaatcac tgttgctaca 27000 tcacgaacgc tttcttatta caaattggga gcttcgcagc gtgtagcagg tgactcaggt 27060 tttgctgcat acagtcgcta caggattggc aactataaat taaacacaga ccattccagt 27120 agcagtgaca atattgcttt gcttgtacag taagtgacaa cagatgtttc atctcgttga 27180 ctttcaggtt actatagcag agatattact aattattatg aggactttta aagtttccat 27240 ttggaatctt gattacatca taaacctcat aattaaaaat ttatctaagt cactaactga 27300 gaataaatat tctcaattag atgaagagca accaatggag attgattaaa cgaacatgaa 27360 aattattctt ttcttggcac tgataacact cgctacttgt gagctttatc actaccaaga 27420 gtgtgttaga ggtacaacag tacttttaaa agaaccttgc tcttctggaa catacgaggg 27480 caattcacca tttcatcctc tagctgataa caaatttgca ctgacttgct ttagcactca 27540 atttgctttt gcttgtcctg acggcgtaaa acacgtctat cagttacgtg ccagatcagt 27600 ttcacctaaa ctgttcatca gacaagagga agttcaagaa ctttactctc caatttttct 27660 tattgttgcg gcaatagtgt ttataacact ttgcttcaca ctcaaaagaa agacagaatg 27720 attgaacttt cattaattga cttctatttg tgctttttag cctttctgct attccttgtt 27780 ttaattatgc ttattatctt ttggttctca cttgaactgc aagatcataa tgaaacttgt 27840 cacgcctaaa ctaacatgaa atttcttgtt ttcttaggaa tcatcacaac tgtagctgca 27900 tttcaccaag aatgtagttt acagtcatgt actcaacatc aaccatatgt agttgatgac 27960 ccgtgtccta ttcacttcta ttctaaatgg tatattagag taggagctag aaaatcagca 28020 cctttaattg aattgtgcgt ggatgaggct ggttctaaat cacccattca gtacatcgat 28080 atcggtaatt atacagtttc ctgtttacct tttacaatta attgccagga acctaaattg 28140 ggtagtcttg tagtgcgttg ttcgttctat gaagactttt tagagtatca tgacgttcgt 28200 gttgttttag atttcatcta aacgaacaaa ctataatgtc tgataatgga ccccaaaatc 28260 agcgaaatgc accccgcatt acgtttggtg gaccctcaga ttcaactggc agtaaccaga 28320 atggagaacg cagtggggcg cgatcaaaac aacgtcggcc ccaaggttta cccaataata 28380 ctgcgtcttg gttcaccgct ctcactcaac atggcaagga agaccttaaa ttccctcgag 28440 gacaaggcgt tccaattaac accaatagca gtccagatga ccaaattggc tactaccgaa 28500 gagctaccag acgaattcgt ggtggtgacg gtaaaatgaa agatctcagt ccaagatggt 28560 atttctacta cctaggaact gggccagaag ctggacttcc ctatggtgct aacaaagacg 28620 gcatcatatg ggttgcaact gagggagcct tgaatacacc aaaagatcac attggcaccc 28680 gcaatcctgc taacaatgct gcaatcgtgc tacaacttcc tcaaggaaca acattgccaa 28740 aaggcttcta cgcagaaggg agcagaggcg gcagtcaagc ctcttctcgt tcctcatcac 28800 gtagtcgcaa cagttcaaga aattcaactc caggcagcag taggggaatt tctcctgcta 28860 gaatggctgg caatggcggt gatgctgctc ttgctttgct gctgcttgac agattgaacc 28920 agcttgagag caaaatgtct ggtaaaggcc aacaacaaca aggccaaact gtcactaaga 28980 aatctgctgc tgaggcttct aagaagcctc ggcaaaaacg tactgccact aaagcataca 29040 atgtaacaca agctttcggc agacgtggtc cagaacaaac ccaaggaaat tttggggacc 29100 aggaactaat cagacaagga actgattaca aacattggcc gcaaattgca caatttgccc 29160 ccagcgcttc agcgttcttc ggaatgtcgc gcattggcat ggaagtcaca ccttcgggaa 29220 cgtggttgac ctacacaggt gccatcaaat tggatgacaa agatccaaat ttcaaagatc 29280 aagtcatttt gctgaataag catattgacg catacaaaac atttccacca acagagccta 29340 aaaaggacaa aaagaagaag gctgatgaaa ctcaagcctt accgcagaga cagaagaaac 29400 agcaaactgt gactcttctt cctgctgcag atttggatga tttctccaaa caattgcaac 29460 aatccatgag cagtgctgac tcaactcagg cctaaactca tgcagaccac acaaggcaga 29520 tgggctatat aaacgttttc gcttttccgt ttacgatata tagtctactc ttgtgcagaa 29580 tgaattctcg taactacata gcacaagtag atgtagttaa ctttaatctc acatagcaat 29640 ctttaatcag tgtgtaacat tagggaggac ttgaaagagc caccacattt tcaccgaggc 29700 cacgcggagt acgatcgagt gtacagtgaa caatgctagg gagagctgcc tatatggaag 29760 agccctaatg tgtaaaatta attttagtag tgctatcccc atgtgatttt aatagc 29816 <210> 27 <211> 1273 <212> PRT <213> SARS-CoV2 <400> 27 Met Phe Val Phe Leu Val Leu Leu Pro Leu Val Ser Ile Gln Cys Val 1 5 10 15 Asn Leu Thr Thr Arg Thr Gln Leu Pro Pro Ala Tyr Thr Asn Ser Phe 20 25 30 Thr Arg Gly Val Tyr Tyr Pro Asp Lys Val Phe Arg Ser Ser Val Leu 35 40 45 Hes Ser Thr Gln Asp Leu Phe Leu Pro Phe Phe Ser Asn Val Thr Trp 50 55 60 Phe Hes Ala Ile Hes Val Ser Gly Thr Asn Gly Thr Lys Arg Phe Asp 65 70 75 80 Asn Pro Val Leu Pro Phe Asn Asp Gly Val Tyr Phe Ala Ser Thr Glu 85 90 95 Lys Ser Asn Ile Ile Arg Gly Trp Ile Phe Gly Thr Thr Leu Asp Ser 100 105 110 Lys Thr Gln Ser Leu Leu Ile Val Asn Asn Ala Thr Asn Val Val Ile 115 120 125 Lys Val Cys Glu Phe Gln Phe Cys Asn Asp Pro Phe Leu Gly Val Tyr 130 135 140 Tyr Hes Lys Asn Asn Lys Ser Cys Met Glu Ser Glu Phe Arg Val Tyr 145 150 155 160 Ser Ser Ala Asn Asn Cys Thr Phe Glu Tyr Val Ser Gln Pro Phe Leu 165 170 175 Met Asp Leu Glu Gly Lys Gln Gly Asn Phe Lys Asn Leu Arg Glu Phe 180 185 190 Val Phe Lys Asn Ile Asp Gly Tyr Phe Lys Ile Tyr Ser Lys Hes Thr 195 200 205 Pro Ile Asn Leu Val Arg Asp Leu Pro Gln Gly Phe Ser Ala Leu Glu 210 215 220 Pro Leu Val Asp Leu Pro Ile Gly Ile Asn Ile Thr Arg Phe Gln Thr 225 230 235 240 Leu Leu Ala Leu Hes Arg Ser Tyr Leu Thr Pro Gly Asp Ser Ser Ser 245 250 255 Gly Trp Thr Ala Gly Ala Ala Ala Tyr Tyr Val Gly Tyr Leu Gln Pro 260 265 270 Arg Thr Phe Leu Leu Lys Tyr Asn Glu Asn Gly Thr Ile Thr Asp Ala 275 280 285 Val Asp Cys Ala Leu Asp Pro Leu Ser Glu Thr Lys Cys Thr Leu Lys 290 295 300 Ser Phe Thr Val Glu Lys Gly Ile Tyr Gln Thr Ser Asn Phe Arg Val 305 310 315 320 Gln Pro Thr Glu Ser Ile Val Arg Phe Pro Asn Ile Thr Asn Leu Cys 325 330 335 Pro Phe Gly Glu Val Phe Asn Ala Thr Arg Phe Ala Ser Val Tyr Ala 340 345 350 Trp Asn Arg Lys Arg Ile Ser Asn Cys Val Ala Asp Tyr Ser Val Leu 355 360 365 Tyr Asn Ser Ala Ser Phe Ser Thr Phe Lys Cys Tyr Gly Val Ser Pro 370 375 380 Thr Lys Leu Asn Asp Leu Cys Phe Thr Asn Val Tyr Ala Asp Ser Phe 385 390 395 400 Val Ile Arg Gly Asp Glu Val Arg Gln Ile Ala Pro Gly Gln Thr Gly 405 410 415 Lys Ile Ala Asp Tyr Asn Tyr Lys Leu Pro Asp Asp Phe Thr Gly Cys 420 425 430 Val Ile Ala Trp Asn Ser Asn Asn Leu Asp Ser Lys Val Gly Gly Asn 435 440 445 Tyr Asn Tyr Arg Tyr Arg Leu Phe Arg Lys Ser Asn Leu Lys Pro Phe 450 455 460 Glu Arg Asp Ile Ser Thr Glu Ile Tyr Gln Ala Gly Ser Thr Pro Cys 465 470 475 480 Asn Gly Val Glu Gly Phe Asn Cys Tyr Phe Pro Leu Gln Ser Tyr Gly 485 490 495 Phe Gln Pro Thr Asn Gly Val Gly Tyr Gln Pro Tyr Arg Val Val Val 500 505 510 Leu Ser Phe Glu Leu Leu Hes Ala Pro Ala Thr Val Cys Gly Pro Lys 515 520 525 Lys Ser Thr Asn Leu Val Lys Asn Lys Cys Val Asn Phe Asn Phe Asn 530 535 540 Gly Leu Thr Gly Thr Gly Val Leu Thr Glu Ser Asn Lys Lys Phe Leu 545 550 555 560 Pro Phe Gln Gln Phe Gly Arg Asp Ile Ala Asp Thr Thr Asp Ala Val 565 570 575 Arg Asp Pro Gln Thr Leu Glu Ile Leu Asp Ile Thr Pro Cys Ser Phe 580 585 590 Gly Gly Val Ser Val Ile Thr Pro Gly Thr Asn Thr Ser Asn Gln Val 595 600 605 Ala Val Leu Tyr Gln Gly Val Asn Cys Thr Glu Val Pro Val Ala Ile 610 615 620 Hes Ala Asp Gln Leu Thr Pro Thr Trp Arg Val Tyr Ser Thr Gly Ser 625 630 635 640 Asn Val Phe Gln Thr Arg Ala Gly Cys Leu Ile Gly Ala Glu Hes Val 645 650 655 Asn Asn Ser Tyr Glu Cys Asp Ile Pro Ile Gly Ala Gly Ile Cys Ala 660 665 670 Ser Tyr Gln Thr Gln Thr Asn Ser Pro Arg Arg Ala Arg Ser Val Ala 675 680 685 Ser Gln Ser Ile Ile Ala Tyr Thr Met Ser Leu Gly Ala Glu Asn Ser 690 695 700 Val Ala Tyr Ser Asn Asn Ser Ile Ala Ile Pro Thr Asn Phe Thr Ile 705 710 715 720 Ser Val Thr Thr Glu Ile Leu Pro Val Ser Met Thr Lys Thr Ser Val 725 730 735 Asp Cys Thr Met Tyr Ile Cys Gly Asp Ser Thr Glu Cys Ser Asn Leu 740 745 750 Leu Leu Gln Tyr Gly Ser Phe Cys Thr Gln Leu Asn Arg Ala Leu Thr 755 760 765 Gly Ile Ala Val Glu Gln Asp Lys Asn Thr Gln Glu Val Phe Ala Gln 770 775 780 Val Lys Gln Ile Tyr Lys Thr Pro Pro Ile Lys Asp Phe Gly Gly Phe 785 790 795 800 Asn Phe Ser Gln Ile Leu Pro Asp Pro Ser Lys Pro Ser Lys Arg Ser 805 810 815 Phe Ile Glu Asp Leu Leu Phe Asn Lys Val Thr Leu Ala Asp Ala Gly 820 825 830 Phe Ile Lys Gln Tyr Gly Asp Cys Leu Gly Asp Ile Ala Ala Arg Asp 835 840 845 Leu Ile Cys Ala Gln Lys Phe Asn Gly Leu Thr Val Leu Pro Pro Leu 850 855 860 Leu Thr Asp Glu Met Ile Ala Gln Tyr Thr Ser Ala Leu Leu Ala Gly 865 870 875 880 Thr Ile Thr Ser Gly Trp Thr Phe Gly Ala Gly Ala Ala Leu Gln Ile 885 890 895 Pro Phe Ala Met Gln Met Ala Tyr Arg Phe Asn Gly Ile Gly Val Thr 900 905 910 Gln Asn Val Leu Tyr Glu Asn Gln Lys Leu Ile Ala Asn Gln Phe Asn 915 920 925 Ser Ala Ile Gly Lys Ile Gln Asp Ser Leu Ser Ser Thr Ala Ser Ala 930 935 940 Leu Gly Lys Leu Gln Asp Val Val Asn Gln Asn Ala Gln Ala Leu Asn 945 950 955 960 Thr Leu Val Lys Gln Leu Ser Ser Asn Phe Gly Ala Ile Ser Ser Val 965 970 975 Leu Asn Asp Ile Leu Ser Arg Leu Asp Lys Val Glu Ala Glu Val Gln 980 985 990 Ile Asp Arg Leu Ile Thr Gly Arg Leu Gln Ser Leu Gln Thr Tyr Val 995 1000 1005 Thr Gln Gln Leu Ile Arg Ala Ala Glu Ile Arg Ala Ser Ala Asn 1010 1015 1020 Leu Ala Ala Thr Lys Met Ser Glu Cys Val Leu Gly Gln Ser Lys 1025 1030 1035 Arg Val Asp Phe Cys Gly Lys Gly Tyr Hes Leu Met Ser Phe Pro 1040 1045 1050 Gln Ser Ala Pro Hes Gly Val Val Phe Leu Hes Val Thr Tyr Val 1055 1060 1065 Pro Ala Gln Glu Lys Asn Phe Thr Thr Ala Pro Ala Ile Cys Hes 1070 1075 1080 Asp Gly Lys Ala Hes Phe Pro Arg Glu Gly Val Phe Val Ser Asn 1085 1090 1095 Gly Thr Hes Trp Phe Val Thr Gln Arg Asn Phe Tyr Glu Pro Gln 1100 1105 1110 Ile Ile Thr Thr Asp Asn Thr Phe Val Ser Gly Asn Cys Asp Val 1115 1120 1125 Val Ile Gly Ile Val Asn Asn Thr Val Tyr Asp Pro Leu Gln Pro 1130 1135 1140 Glu Leu Asp Ser Phe Lys Glu Glu Leu Asp Lys Tyr Phe Lys Asn 1145 1150 1155 Hes Thr Ser Pro Asp Val Asp Leu Gly Asp Ile Ser Gly Ile Asn 1160 1165 1170 Ala Ser Val Val Asn Ile Gln Lys Glu Ile Asp Arg Leu Asn Glu 1175 1180 1185 Val Ala Lys Asn Leu Asn Glu Ser Leu Ile Asp Leu Gln Glu Leu 1190 1195 1200 Gly Lys Tyr Glu Gln Tyr Ile Lys Trp Pro Trp Tyr Ile Trp Leu 1205 1210 1215 Gly Phe Ile Ala Gly Leu Ile Ala Ile Val Met Val Thr Ile Met 1220 1225 1230 Leu Cys Cys Met Thr Ser Cys Cys Ser Cys Leu Lys Gly Cys Cys 1235 1240 1245 Ser Cys Gly Ser Cys Cys Lys Phe Asp Glu Asp Asp Ser Glu Pro 1250 1255 1260 Val Leu Lys Gly Val Lys Leu Hes Tyr Thr 1265 1270 <210> 28 <211> 419 <212> PRT <213> SARS-CoV2 <400> 28 Met Ser Asp Asn Gly Pro Gln Asn Gln Arg Asn Ala Pro Arg Ile Thr 1 5 10 15 Phe Gly Gly Pro Ser Asp Ser Thr Gly Ser Asn Gln Asn Gly Glu Arg 20 25 30 Ser Gly Ala Arg Ser Lys Gln Arg Arg Pro Gln Gly Leu Pro Asn Asn 35 40 45 Thr Ala Ser Trp Phe Thr Ala Leu Thr Gln Hes Gly Lys Glu Asp Leu 50 55 60 Lys Phe Pro Arg Gly Gln Gly Val Pro Ile Asn Thr Asn Ser Ser Pro 65 70 75 80 Asp Asp Gln Ile Gly Tyr Tyr Arg Arg Ala Thr Arg Arg Ile Arg Gly 85 90 95 Gly Asp Gly Lys Met Lys Asp Leu Ser Pro Arg Trp Tyr Phe Tyr Tyr 100 105 110 Leu Gly Thr Gly Pro Glu Ala Gly Leu Pro Tyr Gly Ala Asn Lys Asp 115 120 125 Gly Ile Ile Trp Val Ala Thr Glu Gly Ala Leu Asn Thr Pro Lys Asp 130 135 140 Hes Ile Gly Thr Arg Asn Pro Ala Asn Asn Ala Ala Ile Val Leu Gln 145 150 155 160 Leu Pro Gln Gly Thr Thr Leu Pro Lys Gly Phe Tyr Ala Glu Gly Ser 165 170 175 Arg Gly Gly Ser Gln Ala Ser Ser Arg Ser Ser Ser Arg Ser Arg Asn 180 185 190 Ser Ser Arg Asn Ser Thr Pro Gly Ser Ser Arg Gly Thr Ser Pro Ala 195 200 205 Arg Met Ala Gly Asn Gly Gly Asp Ala Ala Leu Ala Leu Leu Leu Leu 210 215 220 Asp Arg Leu Asn Gln Leu Glu Ser Lys Met Ser Gly Lys Gly Gln Gln 225 230 235 240 Gln Gln Gly Gln Thr Val Thr Lys Lys Ser Ala Ala Glu Ala Ser Lys 245 250 255 Lys Pro Arg Gln Lys Arg Thr Ala Thr Lys Ala Tyr Asn Val Thr Gln 260 265 270 Ala Phe Gly Arg Arg Gly Pro Glu Gln Thr Gln Gly Asn Phe Gly Asp 275 280 285 Gln Glu Leu Ile Arg Gln Gly Thr Asp Tyr Lys Hes Trp Pro Gln Ile 290 295 300 Ala Gln Phe Ala Pro Ser Ala Ser Ala Phe Phe Gly Met Ser Arg Ile 305 310 315 320 Gly Met Glu Val Thr Pro Ser Gly Thr Trp Leu Thr Tyr Thr Gly Ala 325 330 335 Ile Lys Leu Asp Asp Lys Asp Pro Asn Phe Lys Asp Gln Val Ile Leu 340 345 350 Leu Asn Lys Hes Ile Asp Ala Tyr Lys Thr Phe Pro Pro Thr Glu Pro 355 360 365 Lys Lys Asp Lys Lys Lys Lys Ala Asp Glu Thr Gln Ala Leu Pro Gln 370 375 380 Arg Gln Lys Lys Gln Gln Thr Val Thr Leu Leu Pro Ala Ala Asp Leu 385 390 395 400 Asp Asp Phe Ser Lys Gln Leu Gln Gln Ser Met Ser Ser Ala Asp Ser 405 410 415 Thr Gln Ala <210> 29 <211> 222 <212> PRT <213> SARS-CoV2 <400> 29 Met Ala Asp Ser Asn Gly Thr Ile Thr Val Glu Glu Leu Lys Lys Leu 1 5 10 15 Leu Glu Gln Trp Asn Leu Val Ile Gly Phe Leu Phe Leu Thr Trp Ile 20 25 30 Cys Leu Leu Gln Phe Ala Tyr Ala Asn Arg Asn Arg Phe Leu Tyr Ile 35 40 45 Ile Lys Leu Ile Phe Leu Trp Leu Leu Trp Pro Val Thr Leu Ala Cys 50 55 60 Phe Val Leu Ala Ala Val Tyr Arg Ile Asn Trp Ile Thr Gly Gly Ile 65 70 75 80 Ala Ile Ala Met Ala Cys Leu Val Gly Leu Met Trp Leu Ser Tyr Phe 85 90 95 Ile Ala Ser Phe Arg Leu Phe Ala Arg Thr Arg Ser Met Trp Ser Phe 100 105 110 Asn Pro Glu Thr Asn Ile Leu Leu Asn Val Pro Leu Hes Gly Thr Ile 115 120 125 Leu Thr Arg Pro Leu Leu Glu Ser Glu Leu Val Ile Gly Ala Val Ile 130 135 140 Leu Arg Gly Hes Leu Arg Ile Ala Gly Hes Hes Leu Gly Arg Cys Asp 145 150 155 160 Ile Lys Asp Leu Pro Lys Glu Ile Thr Val Ala Thr Ser Arg Thr Leu 165 170 175 Ser Tyr Tyr Lys Leu Gly Ala Ser Gln Arg Val Ala Gly Asp Ser Gly 180 185 190 Phe Ala Ala Tyr Ser Arg Tyr Arg Ile Gly Asn Tyr Lys Leu Asn Thr 195 200 205 Asp Hes Ser Ser Ser Ser Asp Asn Ile Ala Leu Leu Val Gln 210 215 220 <210> 30 <211> 10 <212> ADN <213> Secuencia Artificial <220> <223> Secuencia Artificial <400> 30 aacgttcgag 10 <210> 31 <211> 11 <212> ADN <213> Secuencia Artificial <220> <223> Secuencia Artificial <220> <221> diferentes_características <222> (1)..(11) <223> n=2'-deoxi-7-deazaguanosina <400> 31 tcnaacnttc n 11 <210> 32 <211> 23 <212> ADN <213> Secuencia Artificial <220> <223> Secuencia Artificial <220> <221> diferentes_características <222> (1)..(11) <223> n=2'- deoxi-7-deazaguanosina <220> <221> diferentes_características <222> (12)..(12) <223> x=glicerol <220> <221> diferentes_características <222> (13)..(23) <223> n=2'- deoxi-7-deazaguanosina <400> 32 tcnaacnttc nnncttncaa nct 23