WO 4525.074PC02 US 63/297,787 2022-01-09 KRIYA THERAPEUTICS, INC. CONSTRUCCIONES DE VECTORES PARA LA DISTRIBUCIÓN DE ÁCIDOS NUCLEICOS QUE CODIFICAN ANTICUERPOS TERAPÉUTICOS ANTI-IGF-1R Y MÉTODOS PARA USARLOS 122 5 AA PAT source 1..5 mol_type protein note Variable Heavy Chain CDR1 organism synthetic construct SYGMH 17 AA PAT source 1..17 mol_type protein note Variable Heavy Chain CDR2 organism synthetic construct IIWFDGSSTYYADSVRG 9 AA PAT source 1..9 mol_type protein note Variable Heavy Chain CDR3 organism synthetic construct ELGRRYFDL 11 AA PAT source 1..11 mol_type protein note Variable Light Chain CDR1 organism synthetic construct RASQSVSSYLA 7 AA PAT source 1..7 mol_type protein note Variable Light Chain CDR2 organism synthetic construct DASKRAT 10 AA PAT source 1..10 mol_type protein note Variable Light Chain CDR3 organism synthetic construct QQRSKWPPWT 15 DNA PAT source 1..15 mol_type other DNA note teprotumumab (anti-IGF-1R #1) VH CDR 1 organism synthetic construct tcctacgggatgcat 51 DNA PAT source 1..51 mol_type other DNA note teprotumumab (anti-IGF-1R #1) VH CDR 2 organism synthetic construct atcatttggttcgacggatcttcaacttattacgccgatagtgttcgaggg 27 DNA PAT source 1..27 mol_type other DNA note teprotumumab (anti-IGF-1R #1) VH CDR 3 organism synthetic construct gagctgggccgccggtattttgacctt 15 DNA PAT source 1..15 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #2) VH CDR 1 organism synthetic construct tcctatgggatgcat 51 DNA PAT source 1..51 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #2) VH CDR 2 organism synthetic construct atcatttggtttgatggatcttcaacttattatgctgatagtgttagaggg 27 DNA PAT source 1..27 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #2) VH CDR 3 organism synthetic construct gagctgggccgcagatattttgacctt 15 DNA PAT source 1..15 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #3) VH CDR 1 organism synthetic construct tcctatgggatgcat 51 DNA PAT source 1..51 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #3) VH CDR 2 organism synthetic construct atcatttggtttgatggatcttcaacttattatgctgatagtgttaggggg 27 DNA PAT source 1..27 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #3) VH CDR 3 organism synthetic construct gagctgggcagaaggtattttgacctt 33 DNA PAT source 1..33 mol_type other DNA note teprotumumab (anti-IGF-1R #1) VL CDR 1 organism synthetic construct agggcctcccagtctgtttcaagttatctggct 21 DNA PAT source 1..21 mol_type other DNA note teprotumumab (anti-IGF-1R #1) VL CDR 2 organism synthetic construct gacgcaagcaaacgagccacc 30 DNA PAT source 1..30 mol_type other DNA note teprotumumab (anti-IGF-1R #1) VL CDR 3 organism synthetic construct cagcagcggagtaagtggccaccctggaca 33 DNA PAT source 1..33 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #2) VL CDR 1 organism synthetic construct agggcctcccagtctgtttcaagttatctggct 21 DNA PAT source 1..21 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #2) VL CDR 2 organism synthetic construct gatgcaagcaaaagggccaca 30 DNA PAT source 1..30 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #2) VL CDR 3 organism synthetic construct cagcagcggagtaagtggccaccctggaca 33 DNA PAT source 1..33 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #3) VL CDR 1 organism synthetic construct agggcctcccagtctgtttcaagttatctggct 21 DNA PAT source 1..21 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #3) VL CDR 2 organism synthetic construct gatgcaagcaaaagagccaca 30 DNA PAT source 1..30 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #3) VL CDR 3 organism synthetic construct cagcagagaagtaagtggccaccctggaca 354 DNA PAT source 1..354 mol_type other DNA note teprotumumab (anti-IGF-1R #1) VH organism synthetic construct caggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctca 354 DNA PAT source 1..354 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #2) VH organism synthetic construct caggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctca 354 DNA PAT source 1..354 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #3) VH organism synthetic construct caggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctca 118 AA PAT source 1..118 mol_type protein note Variable Heavy Chain organism synthetic construct QVELVESGGGVVQPGRSQRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAIIWFDGSSTYYADSVRGRFTISRDNSKNTLYLQMNSLRAEDTAVYFCARELGRRYFDLWGRGTLVSVSS 324 DNA PAT source 1..324 mol_type other DNA note teprotumumab (anti-IGF-1R #1) VL organism synthetic construct gagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaag 324 DNA PAT source 1..324 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #2) VL organism synthetic construct gagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaag 324 DNA PAT source 1..324 mol_type other DNA note Modified teprotumumab (anti-IGF-1R #3) VL organism synthetic construct gagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaag 108 AA PAT source 1..108 mol_type protein note Variable Light Chain organism synthetic construct EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASKRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSKWPPWTFGQGTKVESK 321 DNA PAT source 1..321 mol_type other DNA note LC Constant #1 organism synthetic construct agaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgt 990 DNA PAT source 1..990 mol_type other DNA note HC Constant #1 organism synthetic construct gcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaa 1398 DNA PAT source 1..1398 mol_type other DNA note HC #1 organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaa 1397 DNA PAT source 1..1397 mol_type other DNA note HC #2 organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgagcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaa 1398 DNA PAT source 1..1398 mol_type other DNA note HC #3 organism synthetic construct atgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaa 448 AA PAT source 1..448 mol_type protein note Heavy Chain Amino Acid Sequence organism synthetic construct QVELVESGGGVVQPGRSQRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAIIWFDGSSTYYADSVRGRFTISRDNSKNTLYLQMNSLRAEDTAVYFCARELGRRYFDLWGRGTLVSVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 705 DNA PAT source 1..705 mol_type other DNA note LC #1 organism synthetic construct atgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgt 705 DNA PAT source 1..705 mol_type other DNA note LC #2 organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgt 705 DNA PAT source 1..705 mol_type other DNA note LC #3 organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgt 215 AA PAT source 1..215 mol_type protein note Light Chain Amino Acid Sequence organism synthetic construct EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASKRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSKWPPWTFGQGTKVESKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 585 DNA PAT source 1..585 mol_type other DNA note IRES Sequence organism synthetic construct gcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccaca 24 DNA PAT source 1..24 mol_type other DNA note Furin Cleavage Site organism synthetic construct agaaagagaaggagtggctcagga 72 DNA PAT source 1..72 mol_type other DNA note F2A site organism synthetic construct gcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtcca 97 DNA PAT source 1..97 mol_type other DNA note SV40 intron organism synthetic construct gtaagtttagtctttttgtcttttatttcaggtcccggatccggtggtggtgcaaatcaaagaactgctcctcagtggatgttgcctttacttctag 230 DNA PAT source 1..230 mol_type other DNA note EF-1(alpha) organism synthetic construct gctccggtgcccgtcagtgggcagagcgcacatcgcccacagtccccgagaagttggggggaggggtcggcaattgaaccggtgcctagagaaggtggcgcggggtaaactgggaaagtgatgtcgtgtactggctccgcctttttcccgagggtgggggagaaccgtatataagtgcagtagtcgccgtgaacgttctttttcgcaacgggtttgccgccagaacacag 380 DNA PAT source 1..380 mol_type other DNA note CMV enhancer organism synthetic construct gacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatg 218 DNA PAT source 1..218 mol_type other DNA note CMV promoter (CMVp) organism synthetic construct gtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctcgtttagtgaaccg 598 DNA PAT source 1..598 mol_type other DNA note CMV enhancer and promoter (CMVe/p) organism synthetic construct gacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctcgtttagtgaaccg 1725 DNA PAT source 1..1725 mol_type other DNA note CMV enhancer - CBA promoter - CAG intron organism synthetic construct gtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaa 49 DNA PAT source 1..49 mol_type other DNA note Synthetic poly(A) organism synthetic construct aataaaagatctttattttcattagatctgtgtgttggttttttgtgtg 224 DNA PAT source 1..224 mol_type other DNA note BGH poly(A) organism synthetic construct ctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatg 92 DNA PAT source 1..92 mol_type other DNA note Pause element organism synthetic construct aacatacgctctccatcaaaacaaaacgaaacaaaacaaactagcaaaataggctgtccccagtgcaagtgcaggtgccagaacatttctct 269 DNA PAT source 1..269 mol_type other DNA note 5' LTR (truncated) organism synthetic construct ggggctcgcatctctccttcacgcgcccgccgccctacctgaggccgccatccacgccggttgagtcgcgttctgccgcctcccgcctgtggtgcctcctgaactgcgtccgccgtctaggtaagtttaaagctcaggtcgagaccgggcctttgtccggcgctcccttggagcctacctagactcagccggctctccacgctttgcctgaccctgcttgctcaactctacgtctttgtttcgttttctgttctgcgccgttacagatc 133 DNA PAT source 1..133 mol_type other DNA note Intron (chimera of human betaglobin intron and immunoglobulin heavy chain intron) organism synthetic construct gtaagtatcaaggttacaagacaggtttaaggagaccaatagaaactgggcttgtcgagacagagaagactcttgcgtttctgataggcacctattggtcttactgacatccactttgcctttctctccacag 2202 DNA PAT source 1..2202 mol_type other DNA note ORF #1 organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttag 2202 DNA PAT source 1..2202 mol_type other DNA note ORF #2 organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 1401 DNA PAT source 1..1401 mol_type other DNA note ORF #3 organism synthetic construct atgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 708 DNA PAT source 1..708 mol_type other DNA note ORF #4 organism synthetic construct atgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttag 1401 DNA PAT source 1..1401 mol_type other DNA note ORF #5 organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaatag 708 DNA PAT source 1..708 mol_type other DNA note ORF #6 organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 1401 DNA PAT source 1..1401 mol_type other DNA note ORF #7 organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 1401 DNA PAT source 1..1401 mol_type other DNA note ORF #8 organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 1401 DNA PAT source 1..1401 mol_type other DNA note ORF #9 organism synthetic construct atgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 708 DNA PAT source 1..708 mol_type other DNA note ORF #10 organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 708 DNA PAT source 1..708 mol_type other DNA note ORF #11 organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 4479 DNA PAT source 1..4479 mol_type other DNA note EC #1 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4799 DNA PAT source 1..4799 mol_type other DNA note EC #2 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaatagtgacaattgaataaaagatctttattttcattagatctgtgtgttggttttttgtgtggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4288 DNA PAT source 1..4288 mol_type other DNA note EC #3 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctcgtttagtgaaccgtcagatcgcctggagaaggaactgaaaaaccagaaagttaactggtaagtttagtctttttgtcttttatttcaggtcccggatccggtggtggtgcaaatcaaagaactgctcctcagtggatgttgcctttacttctaggcctgtacggaagtgttacttctgctctaaaagctgcggaattgtagcccggttaattaagccaccatgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttaggcatgcctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattctcagaactaacatacgctctccatcaaaacaaaacgaaacaaaacaaactagcaaaataggctgtccccagtgcaagtgcaggtgccagaacatttctctatcgaaggatctgcgatcgctccggtgcccgtcagtgggcagagcgcacatcgcccacagtccccgagaagttggggggaggggtcggcaattgaaccggtgcctagagaaggtggcgcggggtaaactgggaaagtgatgtcgtgtactggctccgcctttttcccgagggtgggggagaaccgtatataagtgcagtagtcgccgtgaacgttctttttcgcaacgggtttgccgccagaacacagctgaagcttcgaggggctcgcatctctccttcacgcgcccgccgccctacctgaggccgccatccacgccggttgagtcgcgttctgccgcctcccgcctgtggtgcctcctgaactgcgtccgccgtctaggtaagtttaaagctcaggtcgagaccgggcctttgtccggcgctcccttggagcctacctagactcagccggctctccacgctttgcctgaccctgcttgctcaactctacgtctttgtttcgttttctgttctgcgccgttacagatcgaagttggtcgtgaggcactgggcaggtaagtatcaaggttacaagacaggtttaaggagaccaatagaaactgggcttgtcgagacagagaagactcttgcgtttctgataggcacctattggtcttactgacatccactttgcctttctctccacaggtgtccactcccagttcaattacagctcttaaggctagtttaaaccaccatgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaatagcctaggaataaaagatctttattttcattagatctgtgtgttggttttttgtgtgctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4479 DNA PAT source 1..4479 mol_type other DNA note EC #4 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4795 DNA PAT source 1..4795 mol_type other DNA note EC #5 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcaccggcaaatagcaattgaataaaagatctttattttcattagatctgtgtgttggttttttgtgtggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4288 DNA PAT source 1..4288 mol_type other DNA note EC #6 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctcgtttagtgaaccgtcagatcgcctggagaaggaactgaaaaaccagaaagttaactggtaagtttagtctttttgtcttttatttcaggtcccggatccggtggtggtgcaaatcaaagaactgctcctcagtggatgttgcctttacttctaggcctgtacggaagtgttacttctgctctaaaagctgcggaattgtagcccggttaattaagccaccatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcatgcctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattctcagaactaacatacgctctccatcaaaacaaaacgaaacaaaacaaactagcaaaataggctgtccccagtgcaagtgcaggtgccagaacatttctctatcgaaggatctgcgatcgctccggtgcccgtcagtgggcagagcgcacatcgcccacagtccccgagaagttggggggaggggtcggcaattgaaccggtgcctagagaaggtggcgcggggtaaactgggaaagtgatgtcgtgtactggctccgcctttttcccgagggtgggggagaaccgtatataagtgcagtagtcgccgtgaacgttctttttcgcaacgggtttgccgccagaacacagctgaagcttcgaggggctcgcatctctccttcacgcgcccgccgccctacctgaggccgccatccacgccggttgagtcgcgttctgccgcctcccgcctgtggtgcctcctgaactgcgtccgccgtctaggtaagtttaaagctcaggtcgagaccgggcctttgtccggcgctcccttggagcctacctagactcagccggctctccacgctttgcctgaccctgcttgctcaactctacgtctttgtttcgttttctgttctgcgccgttacagatcgaagttggtcgtgaggcactgggcaggtaagtatcaaggttacaagacaggtttaaggagaccaatagaaactgggcttgtcgagacagagaagactcttgcgtttctgataggcacctattggtcttactgacatccactttgcctttctctccacaggtgtccactcccagttcaattacagctcttaaggctagtttaaaccaccatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagcctaggaataaaagatctttattttcattagatctgtgtgttggttttttgtgtgctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4488 DNA PAT source 1..4488 mol_type other DNA note EC #7 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4796 DNA PAT source 1..4796 mol_type other DNA note EC #8 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagcaattgaataaaagatctttattttcattagatctgtgtgttggttttttgtgtggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4288 DNA PAT source 1..4288 mol_type other DNA note EC #9 organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctcgtttagtgaaccgtcagatcgcctggagaaggaactgaaaaaccagaaagttaactggtaagtttagtctttttgtcttttatttcaggtcccggatccggtggtggtgcaaatcaaagaactgctcctcagtggatgttgcctttacttctaggcctgtacggaagtgttacttctgctctaaaagctgcggaattgtagcccggttaattaagccaccatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcatgcctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattctcagaactaacatacgctctccatcaaaacaaaacgaaacaaaacaaactagcaaaataggctgtccccagtgcaagtgcaggtgccagaacatttctctatcgaaggatctgcgatcgctccggtgcccgtcagtgggcagagcgcacatcgcccacagtccccgagaagttggggggaggggtcggcaattgaaccggtgcctagagaaggtggcgcggggtaaactgggaaagtgatgtcgtgtactggctccgcctttttcccgagggtgggggagaaccgtatataagtgcagtagtcgccgtgaacgttctttttcgcaacgggtttgccgccagaacacagctgaagcttcgaggggctcgcatctctccttcacgcgcccgccgccctacctgaggccgccatccacgccggttgagtcgcgttctgccgcctcccgcctgtggtgcctcctgaactgcgtccgccgtctaggtaagtttaaagctcaggtcgagaccgggcctttgtccggcgctcccttggagcctacctagactcagccggctctccacgctttgcctgaccctgcttgctcaactctacgtctttgtttcgttttctgttctgcgccgttacagatcgaagttggtcgtgaggcactgggcaggtaagtatcaaggttacaagacaggtttaaggagaccaatagaaactgggcttgtcgagacagagaagactcttgcgtttctgataggcacctattggtcttactgacatccactttgcctttctctccacaggtgtccactcccagttcaattacagctcttaaggctagtttaaaccaccatgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagcctaggaataaaagatctttattttcattagatctgtgtgttggttttttgtgtgctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 000 12 DNA PAT source 1..12 mol_type other DNA note Kozak Sequence organism synthetic construct gcggccgccatg 000 000 000 1064 DNA PAT source 1..1064 mol_type other DNA note CAG intron organism synthetic construct ggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaa 276 DNA PAT source 1..276 mol_type other DNA note CBA promoter #1 organism synthetic construct tcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcg 1557 DNA PAT source 1..1557 mol_type other DNA note ColE1 origin of replication and kanamycin resistance organism synthetic construct gccagcaaaaggccaggaaccgtaaaaaggccgcgttgctggcgtttttccataggctccgcccccctgacggcgtttccccctggaagctccctcgtgcgctctcctgttccgaccctgccgcttaccggatacctgtccgcctttctcccttcgggaagcgtggcgctttctcatagctcacgctgtaggtatctcagttcggtgtaggtcgttcgctccaagctgggctgtgtgcacgaaccccccgttcagcccgaccgctgcgccttatccggtaactatcgtcttgagtccaacccggtaagacacgacttatcgccactggcagcagccactggtaacaggattagcagagcgaggtatgtaggcggtgctacagagttcttgaagtggtggcctaactacggctacactagaagaacagtatttggtatctgcgctctgctgaagccagttaccttcggaaaaagagttggtagctcttgatccggcaaacaaaccaccgctggtagcggtggtttttttgtttgcaagcagcagattacgcgcagaaaaaaaggatctcaagaagatcctttgatcttttctacggggtctgacgctcagtggaacgaaaactcacgttaagggattttggtcatgagattatcaaaaaggatcttcacctagatccttttaaattaaaaatgaagttttaaatcaagcccaatctgaataatgttacaaccaattaaccaattctgattagaaaaactcatcgagcatcaaatgaaactgcaatttattcatatcaggattatcaataccatatttttgaaaaagccgtttctgtaatgaaggagaaaactcaccgaggcagttccataggatggcaagatcctggtatcggtctgcgattccgactcgtccaacatcaatacaacctattaatttcccctcgtcaaaaataaggttatcaagtgagaaatcaccatgagtgacgactgaatccggtgagaatggcaaaagtttatgcatttctttccagacttgttcaacaggccagccattacgctcgtcatcaaaatcactcgcatcaaccaaaccgttattcattcgtgattgcgcctgagcgagacgaaatacgcgatcgctgttaaaaggacaattacaaacaggaatcgaatgcaaccggcgcaggaacactgccagcgcatcaacaatattttcacctgaatcaggatattcttctaatacctggaatgctgtttttccggggatcgcagtggtgagtaaccatgcatcatcaggagtacggataaaatgcttgatggtcggaagaggcataaattccgtcagccagtttagtctgaccatctcatctgtaacatcattggcaacgctacctttgccatgtttcagaaacaactctggcgcatcgggcttcccatacaagcgatagattgtcgcacctgattgcccgacattatcgcgagcccatttatacccatataaatcagcatccatgttggaatttaatcgcggcctcgacgtttcccgttgaatatggctcat 321 DNA PAT source 1..321 mol_type other DNA note LC Constant #2 organism synthetic construct agaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgt 321 DNA PAT source 1..321 mol_type other DNA note LC Constant #3 organism synthetic construct agaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgt 990 DNA PAT source 1..990 mol_type other DNA note HC Constant #2 organism synthetic construct gcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaa 990 DNA PAT source 1..990 mol_type other DNA note HC Constant #3 organism synthetic construct gcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaa 17 AA PAT source 1..17 mol_type protein note Variable Heavy Chain CDR2 organism synthetic construct IIWFDGSSKYYGDSVKG 7 AA PAT source 1..7 mol_type protein note Variable Light Chain CDR2 organism synthetic construct DASNRAT 118 AA PAT source 1..118 mol_type protein note Variable Heavy Chain organism synthetic construct QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWMAIIWFDGSSKYYGDSVKGRFTISRDNSKNTLYLQMNSLRADDTAVYYCARELGRRYFDLWGRGTLVTVSS 108 AA PAT source 1..108 mol_type protein note Variable Light Chain organism synthetic construct EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSKWPPWTFGQGTKVEIK 278 DNA PAT source 1..278 mol_type other DNA note CBA promoter #2 organism synthetic construct tcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcg 2694 DNA PAT source 1..2694 mol_type other DNA note ORF #12 organism synthetic construct atgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaatag 2700 DNA PAT source 1..2700 mol_type other DNA note ORF #13 organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcaccggcaaatagcaattga 2211 DNA PAT source 1..2211 mol_type other DNA note ORF #14 organism synthetic construct atgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 2694 DNA PAT source 1..2694 mol_type other DNA note ORF #15 organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 20 DNA PAT source 1..20 mol_type other DNA note Heavy Chain Forward Primer organism synthetic construct tctcacgtgcctggttaaag 23 DNA PAT source 1..23 mol_type other DNA note Heavy Chain Reverse Primer organism synthetic construct ggaggtgtggtcttgtagttatt 24 DNA PAT source 1..24 mol_type other DNA note Heavy Chain Probe organism synthetic construct tatcgccgtggagtgggagtctaa 22 DNA PAT source 1..22 mol_type other DNA note Light Chain Forward Primer organism synthetic construct cgccttctgtcttcatctttcc 22 DNA PAT source 1..22 mol_type other DNA note Light Chain Reverse Primer organism synthetic construct cctccctcgggtagaagttatt 24 DNA PAT source 1..24 mol_type other DNA note Light Chain Probe organism synthetic construct tacggcttcagtggtttgtctgct 20 DNA PAT source 1..20 mol_type other DNA note Forward Primer - F2A link -1 organism synthetic construct cctgtgaaacagaccctgaa 18 DNA PAT source 1..18 mol_type other DNA note Probe - F2A link -1 organism synthetic construct tgacctcttgaagcttgc 20 DNA PAT source 1..20 mol_type other DNA note Reverse Primer - F2 link -1 organism synthetic construct tggaccaggattagactcca 20 DNA PAT source 1..20 mol_type other DNA note Forward Primer - F2A link -2 organism synthetic construct cctgtgaaacagaccctgaa 18 DNA PAT source 1..18 mol_type other DNA note Probe - F2A link -2 organism synthetic construct tgacctcttgaagcttgc 20 DNA PAT source 1..20 mol_type other DNA note Reverse Primer - F2A link -2 organism synthetic construct tggaccaggattagactcca 24 DNA PAT source 1..24 mol_type other DNA note Forward Primer - mHPRT1 organism synthetic construct gttaagcagtacagccccaaaatg 30 DNA PAT source 1..30 mol_type other DNA note Probe - mHPRT1 organism synthetic construct agcttgctggtgaaaaggacctctcgaagt 24 DNA PAT source 1..24 mol_type other DNA note Reverse Primer - mHPRT1 organism synthetic construct aaatccaacaaagtctggcctgta 673 AA PAT source 1..673 mol_type protein note VRDN-01100 organism synthetic construct DVVMTQTPLSLPVSLGDPASISCRSSQSIVHSNVNTYLEWYLQKPGQSPRLLIYKVSNRFSGVPDRFSGSGAGTDFTLRISRVEAEDLGIYYCFQGSHVPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLVQSGAEVVKPGASVKLSCKASGYTFTSYWMHWVKQRPGQGLEWIGEINPSNGRTNYNQKFQGKATLTVDKSSSTAYMQLSSLTSEDSAVYYFARGRPDYYGSSKWYFDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 113 AA PAT source 1..113 mol_type protein note VRDN-01100 VL organism synthetic construct DVVMTQTPLSLPVSLGDPASISCRSSQSIVHSNVNTYLEWYLQKPGQSPRLLIYKVSNRFSGVPDRFSGSGAGTDFTLRISRVEAEDLGIYYCFQGSHVPPTFGGGTKLEIKR 124 AA PAT source 1..124 mol_type protein note VRDN-01100 VH organism synthetic construct QVQLVQSGAEVVKPGASVKLSCKASGYTFTSYWMHWVKQRPGQGLEWIGEINPSNGRTNYNQKFQGKATLTVDKSSSTAYMQLSSLTSEDSAVYYFARGRPDYYGSSKWYFDVWGQGTTVTVSS 665 AA PAT source 1..665 mol_type protein note VRDN-02700 organism synthetic construct DIVMTQSPLSLPVTPGEPASISCRSSQSIVHSNGNTYLQWYLQKPGQSPQLLIYKVSNRLYGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCFQGSHVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQESGPGLVKPSETLSLTCTVSGYSITGGYLWNWIRQPPGKGLEWIGYISYDGTNNYKPSLKDRVTISRDTSKNQFSLKLSSVTAADTAVYYCARYGRVFFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLYITREPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG 113 AA PAT source 1..113 mol_type protein note VRDN-02700 VL organism synthetic construct DIVMTQSPLSLPVTPGEPASISCRSSQSIVHSNGNTYLQWYLQKPGQSPQLLIYKVSNRLYGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCFQGSHVPWTFGQGTKVEIKR 117 AA PAT source 1..117 mol_type protein note VRDN-02700 VH organism synthetic construct QVQLQESGPGLVKPSETLSLTCTVSGYSITGGYLWNWIRQPPGKGLEWIGYISYDGTNNYKPSLKDRVTISRDTSKNQFSLKLSSVTAADTAVYYCARYGRVFFDYWGQGTLVTVSS 18 AA PAT source 1..18 mol_type protein note signal peptide IL-10 organism synthetic construct MHSSALLCCLVLLTGVRA 20 AA PAT source 1..20 mol_type protein note signal peptide IL-2 organism synthetic construct MYRMQLLSCIALSLALVTNS 54 DNA PAT source 1..54 mol_type other DNA note signal peptide IL-10 organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggct 60 DNA PAT source 1..60 mol_type other DNA note signal peptide IL-2 organism synthetic construct atgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactct