US 18/335,636 2023-06-15 350794.46701 AbbVie Biotherapeutics, Inc. AbbVie Biotherapeutics, Inc. ANTI-CD19 ANTIBODY DRUG CONJUGATES CONJUGADOS DE ANTICUERPO Y FC
RMACO ANTI-CD19 13 10 AA PAT REGION 1..10 note Description of Artificial Sequence: Synthetic peptide DescripciC3n de la secuencia artificial: PC)ptido sintC)tico source 1..10 mol_type protein organism synthetic construct Constructo sintC)tico GFTFTTYWIN 17 AA PAT REGION 1..17 note Description of Artificial Sequence: Synthetic peptide DescripciC3n de la secuencia artificial: PC)ptido sintC)tico source 1..17 mol_type protein organism synthetic construct Constructo sintC)tico NIYPSDSYTNYNQKFKD 14 AA PAT REGION 1..14 note Description of Artificial Sequence: Synthetic peptide DescripciC3n de la secuencia artificial: PC)ptido sintC)tico source 1..14 mol_type protein organism synthetic construct Constructo sintC)tico EDYYGSSSYYAMDY 11 AA PAT REGION 1..11 note Description of Artificial Sequence: Synthetic peptide DescripciC3n de la secuencia artificial: PC)ptido sintC)tico source 1..11 mol_type protein organism synthetic construct Constructo sintC)tico KASQDVGTAVA 7 AA PAT REGION 1..7 note Description of Artificial Sequence: Synthetic peptide DescripciC3n de la secuencia artificial: PC)ptido sintC)tico source 1..7 mol_type protein organism synthetic construct Constructo sintC)tico WASTRHT 9 AA PAT REGION 1..9 note Description of Artificial Sequence: Synthetic peptide DescripciC3n de la secuencia artificial: PC)ptido sintC)tico source 1..9 mol_type protein organism synthetic construct Constructo sintC)tico QQYSTYPLT 123 AA PAT REGION 1..123 note Description of Artificial Sequence: Synthetic polypeptide DescripciC3n de la secuencia artificial: PolipC)ptido sintC)tico source 1..123 mol_type protein organism synthetic construct Constructo sintC)tico EVQLVESGGGLVQPGGSLRLSCAASGFTFTTYWINWVRQAPGKGLEWIGNIYPSDSYTNYNQKFKDRATLSVDKSKNTAYLQMNSLRAEDTAVYYCTREDYYGSSSYYAMDYWGQGTLVTVSS 107 AA PAT REGION 1..107 note Description of Artificial Sequence: Synthetic polypeptide DescripciC3n de la secuencia artificial: PolipC)ptido sintC)tico source 1..107 mol_type protein organism synthetic construct Constructo sintC)tico AILMTQSPSSLSASVGDRVTITCKASQDVGTAVAWYQQKPGKAPKLLIYWASTRHTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTYPLTFGQGTKVEIK 453 AA PAT REGION 1..453 note Description of Artificial Sequence: Synthetic polypeptide DescripciC3n de la secuencia artificial: PolipC)ptido sintC)tico source 1..453 mol_type protein organism synthetic construct Constructo sintC)tico EVQLVESGGGLVQPGGSLRLSCAASGFTFTTYWINWVRQAPGKGLEWIGNIYPSDSYTNYNQKFKDRATLSVDKSKNTAYLQMNSLRAEDTAVYYCTREDYYGSSSYYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 214 AA PAT REGION 1..214 note Description of Artificial Sequence: Synthetic polypeptide DescripciC3n de la secuencia artificial: PolipC)ptido sintC)tico source 1..214 mol_type protein organism synthetic construct Constructo sintC)tico AILMTQSPSSLSASVGDRVTITCKASQDVGTAVAWYQQKPGKAPKLLIYWASTRHTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTYPLTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 452 AA PAT REGION 1..452 note Description of Artificial Sequence: Synthetic polypeptide DescripciC3n de la secuencia artificial: PolipC)ptido sintC)tico source 1..452 mol_type protein organism synthetic construct Constructo sintC)tico EVQLVESGGGLVQPGGSLRLSCAASGFTFTTYWINWVRQAPGKGLEWIGNIYPSDSYTNYNQKFKDRATLSVDKSKNTAYLQMNSLRAEDTAVYYCTREDYYGSSSYYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG 1419 DNA PAT misc_feature 1..1419 note Description of Artificial Sequence: Synthetic polynucleotide DescripciC3n de la secuencia artificial: PolinucleC3tido sintC)tico source 1..1419 mol_type other DNA organism synthetic construct Constructo sintC)tico atggagtttgggctgagctggctttttcttgtcgcgattttaaaaggagtccagtgcgaggtgcagctggttgaatctggcggaggactggttcagcctggcggatctctgagactgtcttgtgccgccagcggcttcaccttcaccacctactggatcaactgggtccgacaggcccctggcaaaggcctggaatggatcggcaacatctaccccagcgacagctacaccaactacaaccagaagttcaaggaccgggccacactgagcgtggacaagagcaagaataccgcctacctgcagatgaacagcctgagagccgaggacaccgccgtgtactactgcaccagagaggactactacggcagcagcagctactacgccatggactattggggccagggcaccctggttaccgttagctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacccagacctacatctgcaacgtgaatcacaagcccagcaacaccaaggtggacaagaaagttgagcccaaatcttgtgacaaaactcacacatgcccaccgtgcccagcacctgaactcctggggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctcatgatctcccggacccctgaggtcacatgcgtggtggtggacgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtctccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgacctgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcaggtggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagagcctctccctgtctccgggtaaatga 711 DNA PAT misc_feature 1..711 note Description of Artificial Sequence: Synthetic polynucleotide DescripciC3n de la secuencia artificial: PolinucleC3tido sintC)tico source 1..711 mol_type other DNA organism synthetic construct Constructo sintC)tico atggacatgcgcgtgcccgcccagctgctgggcctgctgctgctgtggttccccggctcgcgatgcgccatcctgatgacacagagcccttctagcctgagcgccagcgtgggagacagagtgaccatcacctgtaaagccagccaggatgtgggaacagccgtggcctggtatcagcagaagcctggaaaggcccctaagctgctgatctactgggccagcacaagacacacaggcgtgcccagcagattttctggcagcggctctggcaccgacttcaccctgaccatatctagcctgcagcctgaggacttcgccacctactactgccagcagtacagcacataccctctgacctttggccagggcaccaaggtggaaatcaaacgaactgtggctgcaccatctgtcttcatcttcccgccatctgatgagcagttgaaatctggaactgcctctgttgtgtgcctgctgaataacttctatcccagagaggccaaagtacagtggaaggtggataacgccctccaatcgggtaactcccaggagagtgtcacagagcaggacagcaaggacagcacctacagcctcagcagcaccctgacgctgagcaaagcagactacgagaaacacaaagtctacgcctgcgaagtcacccatcagggcctgagctcgcccgtcacaaagagcttcaacaggggagagtgttag