WO 18395-20350.40 US 63/443,223 2023-02-03 Genzyme Corporation NANOPARTÍCULAS LIPIDAS CONJUGADAS CON ANTICUERPOS ESPECÍFICOS DE CMH Y USOS DE LAS MISMAS 62 9 AA PAT source 1..9 mol_type protein organism Constructo sintético FTFSNYAMS 17 AA PAT source 1..17 mol_type protein organism Constructo sintético AISGSGGSTYYADSVKG 16 AA PAT source 1..16 mol_type protein organism Constructo sintético AKGPPTYHTNYYYMDV 11 AA PAT source 1..11 mol_type protein organism Constructo sintético RASQGISSWLA 7 AA PAT source 1..7 mol_type protein organism Constructo sintético AASSLQS 9 AA PAT source 1..9 mol_type protein organism Constructo sintético QQTNSFPYT 123 AA PAT source 1..123 mol_type protein organism Constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFTFSNYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKGPPTYHTNYYYMDVWGKGTTVTVSS 107 AA PAT source 1..107 mol_type protein organism Constructo sintético DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQTNSFPYTFGGGTKVEIK 240 AA PAT source 1..240 mol_type protein organism Constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFTFSNYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKGPPTYHTNYYYMDVWGKGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTCPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSSDKTHTCGGHHHHHH 9 AA PAT source 1..9 mol_type protein organism Constructo sintético FTFSDADMD 19 AA PAT source 1..19 mol_type protein organism Constructo sintético RTRNKAGSYTTEYAASVKG 12 AA PAT source 1..12 mol_type protein organism Constructo sintético AREPKYWIDFDL 11 AA PAT source 1..11 mol_type protein organism Constructo sintético RASQSISSYLN 7 AA PAT source 1..7 mol_type protein organism Constructo sintético AASSLQS 9 AA PAT source 1..9 mol_type protein organism Constructo sintético QQSYIAPYT 121 AA PAT source 1..121 mol_type protein organism Constructo sintético EVQLVESGGGLVQPGGSLRLSCAASGFTFSDADMDWVRQAPGKGLEWVGRTRNKAGSYTTEYAASVKGRFTISRDDSKNSLYLQMNSLKTEDTAVYYCAREPKYWIDFDLWGRGTLVTVSS 107 AA PAT source 1..107 mol_type protein organism Constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYIAPYTFGGGTKVEIK 238 AA PAT source 1..238 mol_type protein organism Constructo sintético EVQLVESGGGLVQPGGSLRLSCAASGFTFSDADMDWVRQAPGKGLEWVGRTRNKAGSYTTEYAASVKGRFTISRDDSKNSLYLQMNSLKTEDTAVYYCAREPKYWIDFDLWGRGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTCPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSSDKTHTCGGHHHHHH 5 AA PAT source 1..5 mol_type protein organism Constructo sintético DAWMD 19 AA PAT source 1..19 mol_type protein organism Constructo sintético EIRSKASNHATYYAESVKG 7 AA PAT source 1..7 mol_type protein organism Constructo sintético WRRFFDS 10 AA PAT source 1..10 mol_type protein organism Constructo sintético RASSSVSYMH 7 AA PAT source 1..7 mol_type protein organism Constructo sintético ATSNLAS 9 AA PAT source 1..9 mol_type protein organism Constructo sintético QQWSSNPLT 118 AA PAT source 1..118 mol_type protein organism Constructo sintético EVKLEESGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQSPEKGLEWVAEIRSKASNHATYYAESVKGRFTISRDDSKSSVYLQMNSLRAEDTGIYYCTRWRRFFDSWGQGTTLTVSS 106 AA PAT source 1..106 mol_type protein organism Constructo sintético QIVLSQSPAILSASPGEKVTMTCRASSSVSYMHWYQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWSSNPLTFGAGTKLELK 235 AA PAT source 1..235 mol_type protein organism Constructo sintético EVKLEESGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQSPEKGLEWVAEIRSKASNHATYYAESVKGRFTISRDDSKSSVYLQMNSLRAEDTGIYYCTRWRRFFDSWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTCPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSSDKTHTCGGHHHHHH 9 AA PAT source 1..9 mol_type protein organism Constructo sintético FAAANYAMS 17 AA PAT source 1..17 mol_type protein organism Constructo sintético AISGAAASTYYADSVKG 16 AA PAT source 1..16 mol_type protein organism Constructo sintético AKGPPTYAAAYYYMDV 11 AA PAT source 1..11 mol_type protein organism Constructo sintético RASQAAASWLA 7 AA PAT source 1..7 mol_type protein organism Constructo sintético AAASLQS 9 AA PAT source 1..9 mol_type protein organism Constructo sintético QQTAAAPYT 123 AA PAT source 1..123 mol_type protein organism Constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFAAANYAMSWVRQAPGKGLEWVSAISGAAASTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKGPPTYAAAYYYMDVWGKGTTVTVSS 107 AA PAT source 1..107 mol_type protein organism Constructo sintético DIQMTQSPSSVSASVGDRVTITCRASQAAASWLAWYQQKPGKAPKLLIYAAASLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQTAAAPYTFGGGTKVEIK 240 AA PAT source 1..240 mol_type protein organism Constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFAAANYAMSWVRQAPGKGLEWVSAISGAAASTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKGPPTYAAAYYYMDVWGKGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTCPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSSDKTHTCGGHHHHHH 214 AA PAT source 1..214 mol_type protein organism Constructo sintético DIQMTQSPSSVSASVGDRVTITCRASQAAASWLAWYQQKPGKAPKLLIYAAASLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQTAAAPYTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLCSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGES 214 AA PAT source 1..214 mol_type protein organism Constructo sintético DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQTNSFPYTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLCSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGES 214 AA PAT source 1..214 mol_type protein organism Constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYIAPYTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLCSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGES 213 AA PAT source 1..213 mol_type protein organism Constructo sintético QIVLSQSPAILSASPGEKVTMTCRASSSVSYMHWYQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWSSNPLTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLCSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGES 98 AA PAT source 1..98 mol_type protein organism Constructo sintético ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTCPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKV 19 AA PAT source 1..19 mol_type protein organism Constructo sintético EPKSSDKTHTCGGHHHHHH 107 AA PAT source 1..107 mol_type protein organism Constructo sintético RTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLCSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGES 000 5 AA PAT source 1..5 mol_type protein organism Constructo sintético GGGGS 7 AA PAT source 1..7 mol_type protein organism Constructo sintético SGGSGGS 8 AA PAT source 1..8 mol_type protein organism Constructo sintético GGGGSGGS 9 AA PAT source 1..9 mol_type protein organism Constructo sintético GGGGSGGGS 10 AA PAT source 1..10 mol_type protein organism Constructo sintético GGGGSGGGGS 15 AA PAT source 1..15 mol_type protein organism Constructo sintético GGGGSGGGGSGGGGS 18 AA PAT source 1..18 mol_type protein organism Constructo sintético GGGGSGGGGSGGGGSGGS 20 AA PAT source 1..20 mol_type protein organism Constructo sintético GGGGSGGGGSGGGGSGGGGS 25 AA PAT source 1..25 mol_type protein organism Constructo sintético GGGGSGGGGSGGGGSGGGGSGGGGS 30 AA PAT source 1..30 mol_type protein organism Constructo sintético GGGGSGGGGSGGGGSGGGGSGGGGSGGGGS 35 AA PAT source 1..35 mol_type protein organism Constructo sintético GGGGSGGGGSGGGGSGGGGSGGGGSGGGGSGGGGS 40 AA PAT source 1..40 mol_type protein organism Constructo sintético GGGGSGGGGSGGGGSGGGGSGGGGSGGGGSGGGGSGGGGS 15 AA PAT source 1..15 mol_type protein organism Constructo sintético EPKSCDKTHTCPPCP 24 AA PAT source 1..24 mol_type protein organism Constructo sintético GGGGSGGGSEPKSCDKTHTCPPCP 12 AA PAT source 1..12 mol_type protein organism Constructo sintético EPKTPKPQPAAA 62 AA PAT source 1..62 mol_type protein organism Constructo sintético ELKTPLGDTTHTCPRCPEPKSCDTPPPCPRCPEPKSCDTPPPCPRCPEPKSCDTPPPCPRCP 9 AA PAT source 1..9 mol_type protein organism Constructo sintético LAGLIDADG 20 DNA PAT source 1..20 mol_type otro ADN organism Constructo sintético gtgataaaagcaactgttag