C1-A2205P JP 2023-019304 2023-02-10 CHUGAI SEIYAKU KABUSHIKI KAISHA ANTI-LATENT TGF-BETA 1 ANTIBODIES AND METHODS OF USE ANTICUERPOS ANTI-TGF-BETA 1 LATENTE Y MÉTODOS DE USO 108 122 AA PAT source 1..122 mol_type protein note T0947H0053H0066 T0947H0053H0066 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFTFSSEAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGTGIYDYYYWVMDLWGPGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H0156 T0947H0053H0156 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFTFSSEAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGTHIYDHYYWVHHLWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H1184 T0947H0053H1184 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFTFSNEAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHQYWVMHFWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H1185 T0947H0053H1185 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFLFSREAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHQYWVMHFWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H1222 T0947H0053H1222 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSREAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHHYWVMHFWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H1890 T0947H0053H1890 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSNEAMNWIRQPPGKGLEWIGYIYTSGTTYRSNWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHQYWVMHFWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H2151 T0947H0053H2151 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSREAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGTHLFGHHYWVMHSWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H2158 T0947H0053H2158 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSSEAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHHYWVMHFWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H3061 T0947H0053H3061 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSNEAMNWIRQPPGKGLEWIGYIYTTGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHHYWVMHFWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H3254 T0947H0053H3254 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSSEAMNWIRQPPGKGLEWIGYIYVSGTTYRADWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHHYWVMHAWGQGTLVTVSS 122 AA PAT source 1..122 mol_type protein note T0947H0053H3306 T0947H0053H3306 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSSEAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFDHHYWVMHAWGQGTLVTVSS 108 AA PAT source 1..108 mol_type protein note T0947L001L0049 T0947L001L0049 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYLAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVGFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0083 T0947L001L0083 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYEAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVGFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0096 T0947L001L0096 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYLAWYQQKPGQPPKLLIYAASTLEWGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVGFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0109 T0947L001L0109 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYLAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0127 T0947L001L0127 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYEAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0215 T0947L001L0215 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYLAWYQQKPGQPPKLLIYAASTLEYGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0226 T0947L001L0226 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYLAWYQQKPGQPPKLLIYAASTLEYGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVVFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0290 T0947L001L0290 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYEAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVKFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0386 T0947L001L0386 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASESISTYLAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein note T0947L001L0936 T0947L001L0936 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQRISTYVAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIK 328 AA PAT source 1..328 mol_type protein note SG181 SG181 organism synthetic construct constructo sintético ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 328 AA PAT source 1..328 mol_type protein note SG191 SG191 organism synthetic construct constructo sintético ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVLHEALHAHYTRKELSLSP 324 AA PAT source 1..324 mol_type protein note mF18 mF18 organism synthetic construct constructo sintético AKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICTVKEVSKVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVEVHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNSAAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMITDFFPEDITVEWQWNGQPAENYKNTQPIMDTDGSYFVYSKLNVQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGK 107 AA PAT source 1..107 mol_type protein note SK1 SK1 organism synthetic construct constructo sintético RTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 107 AA PAT source 1..107 mol_type protein note mK1 mK1 organism synthetic construct constructo sintético RADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 5 AA PAT source 1..5 mol_type protein note HCDR1 HCDR1 organism synthetic construct constructo sintético SEAMN 5 AA PAT source 1..5 mol_type protein note HCDR1 HCDR1 organism synthetic construct constructo sintético NEAMN 5 AA PAT source 1..5 mol_type protein note HCDR1 HCDR1 organism synthetic construct constructo sintético REAMN 16 AA PAT source 1..16 mol_type protein note HCDR2 HCDR2 organism synthetic construct constructo sintético YIYTSGTTYRANWARG 16 AA PAT source 1..16 mol_type protein note HCDR2 HCDR2 organism synthetic construct constructo sintético YIYTSGTTYRSNWARG 16 AA PAT source 1..16 mol_type protein note HCDR2 HCDR2 organism synthetic construct constructo sintético YIYTTGTTYRANWARG 16 AA PAT source 1..16 mol_type protein note HCDR2 HCDR2 organism synthetic construct constructo sintético YIYVSGTTYRADWARG 14 AA PAT source 1..14 mol_type protein note HCDR3 HCDR3 organism synthetic construct constructo sintético GTGIYDYYYWVMDL 14 AA PAT source 1..14 mol_type protein note HCDR3 HCDR3 organism synthetic construct constructo sintético GTHIYDHYYWVHHL 14 AA PAT source 1..14 mol_type protein note HCDR3 HCDR3 organism synthetic construct constructo sintético GWHIFGHQYWVMHF 14 AA PAT source 1..14 mol_type protein note HCDR3 HCDR3 organism synthetic construct constructo sintético GWHIFGHHYWVMHF 14 AA PAT source 1..14 mol_type protein note HCDR3 HCDR3 organism synthetic construct constructo sintético GTHLFGHHYWVMHS 14 AA PAT source 1..14 mol_type protein note HCDR3 HCDR3 organism synthetic construct constructo sintético GWHIFDHHYWVMHA 14 AA PAT source 1..14 mol_type protein note HCDR3 HCDR3 organism synthetic construct constructo sintético GWHIFGHHYWVMHA 30 AA PAT source 1..30 mol_type protein note HFR1 HFR1 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFTFS 30 AA PAT source 1..30 mol_type protein note HFR1 HFR1 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFLFS 30 AA PAT source 1..30 mol_type protein note HFR1 HFR1 organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFS 14 AA PAT source 1..14 mol_type protein note HFR2 HFR2 organism synthetic construct constructo sintético WIRQPPGKGLEWIG 32 AA PAT source 1..32 mol_type protein note HFR3 HFR3 organism synthetic construct constructo sintético RFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR 11 AA PAT source 1..11 mol_type protein note HFR4 HFR4 organism synthetic construct constructo sintético WGPGTLVTVSS 11 AA PAT source 1..11 mol_type protein note HFR4 HFR4 organism synthetic construct constructo sintético WGQGTLVTVSS 11 AA PAT source 1..11 mol_type protein note LCDR1 LCDR1 organism synthetic construct constructo sintético QASQSISTYLA 11 AA PAT source 1..11 mol_type protein note LCDR1 LCDR1 organism synthetic construct constructo sintético QASQSISTYEA 11 AA PAT source 1..11 mol_type protein note LCDR1 LCDR1 organism synthetic construct constructo sintético QASQRISTYVA 11 AA PAT source 1..11 mol_type protein note LCDR1 LCDR1 organism synthetic construct constructo sintético QASESISTYLA 7 AA PAT source 1..7 mol_type protein note LCDR2 LCDR2 organism synthetic construct constructo sintético AASTLES 7 AA PAT source 1..7 mol_type protein note LCDR2 LCDR2 organism synthetic construct constructo sintético AASTLEY 7 AA PAT source 1..7 mol_type protein note LCDR2 LCDR2 organism synthetic construct constructo sintético AASTLEW 10 AA PAT source 1..10 mol_type protein note LCDR3 LCDR3 organism synthetic construct constructo sintético QSYSDGDSVG 10 AA PAT source 1..10 mol_type protein note LCDR3 LCDR3 organism synthetic construct constructo sintético QSYSDGDSVI 10 AA PAT source 1..10 mol_type protein note LCDR3 LCDR3 organism synthetic construct constructo sintético QVYSDGDSVI 10 AA PAT source 1..10 mol_type protein note LCDR3 LCDR3 organism synthetic construct constructo sintético QSYSDGDSVV 10 AA PAT source 1..10 mol_type protein note LCDR3 LCDR3 organism synthetic construct constructo sintético QSYSDGDSVK 23 AA PAT source 1..23 mol_type protein note LFR1 LFR1 organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITC 15 AA PAT source 1..15 mol_type protein note LFR2 LFR2 organism synthetic construct constructo sintético WYQQKPGQPPKLLIY 32 AA PAT source 1..32 mol_type protein note LFR3 LFR3 organism synthetic construct constructo sintético GVPSRFSGSGSGTDFTLTISSLQPEDFATYYC 10 AA PAT source 1..10 mol_type protein note LFR4 LFR4 organism synthetic construct constructo sintético FGQGTKVEIK 387 AA PAT source 1..387 mol_type protein note human TGFb1 SLC_C33S_N-Flag_Furin TGFb1 humano SLC_C33S_N-Flag_Furina organism synthetic construct constructo sintético MKWVTFLLLLFISGSAFSDYKDDDDKLSTSKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 387 AA PAT source 1..387 mol_type protein note mouse TGFb1 SLC N-Flag_Furin TGFb1 de ratón SLC N-Flag_Furina organism synthetic construct constructo sintético MKWVTFLLLLFISGSAFSDYKDDDDKLSTSKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVDRNNAIYEKTKDISHSIYMFFNTSDIREAVPEPPLLSRAELRLQRLKSSVEQHVELYQKYSNNSWRYLGNRLLTPTDTPEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNKLHVEINGISPKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 387 AA PAT source 1..387 mol_type protein note cyno TGFb1 SLC-Flag_Furin TGFb1 de Macaca fascicularis SLC-Flag_Furina organism synthetic construct constructo sintético MKWVTFLLLLFISGSAFSDYKDDDDKLSTSKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSKDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 18 AA PAT source 1..18 mol_type protein note Rabit serum albumin signal peptide Péptido de señal de albúmina de suero de conejo organism Rattus norvegicus Rattus norvegicus MKWVTFLLLLFISGSAFS 444 AA PAT source 1..444 mol_type protein note IC17-hIgG1 (Hch) IC17-hIgG1 (Hch) organism synthetic construct constructo sintético QVQLQQSGPQLVRPGASVNISCKASGYSFTSYWMHWVNQRPGQGLEWIGMIDPSYSETRLNQKFKDKATLTVDKSSSTAYMQLSSPTSEDSAVYYCALYGNYFDYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELRRGPKVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 214 AA PAT source 1..214 mol_type protein note IC17-hIgG1 (Lch) IC17-hIgG1 (Lch) organism synthetic construct constructo sintético DIQMTQSSSSFSVSLGDRVTITCKASEDIYNRLAWYQQKPGNAPRLLISGATSLETGVPSRFSGSGSGKDYTLSITSLQTEDVATYYCQQYWSTPYTFGGGTKLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 444 AA PAT source 1..444 mol_type protein note IC17dk-SG181 (Hch) IC17dk-SG181 (Hch) organism synthetic construct constructo sintético QVQLQQSGPQLVRPGASVKISCKASGYSFTSYWMHWVNQRPGQGLEWIGMIDPSYSETRLNQKFKDKATLTVDKSSSTAYMQLSSPTSEDSAVYYCALYGNYFDYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 214 AA PAT source 1..214 mol_type protein note IC17dk-SG181 (Lch IC17dk-SG181 (Lch organism synthetic construct constructo sintético DIQMTQSSSSFSVSLGDRVTITCKASEDIYNRLAWYQQKPGNAPRLLISGATSLETGVPSRFSGSGSGKDYTLSITSLQTEDVATYYCQQYWSTPYTFGGGTKLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 440 AA PAT source 1..440 mol_type protein note IC17dk-mF18 (Hch) IC17dk-mF18 (Hch) organism synthetic construct constructo sintético QVQLQQSGPQLVRPGASVKISCKASGYSFTSYWMHWVNQRPGQGLEWIGMIDPSYSETRLNQKFKDKATLTVDKSSSTAYMQLSSPTSEDSAVYYCALYGNYFDYWGQGTTLTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICTVKEVSKVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVEVHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNSAAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMITDFFPEDITVEWQWNGQPAENYKNTQPIMDTDGSYFVYSKLNVQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGK 214 AA PAT source 1..214 mol_type protein note IC17dk-mF18 (Lch) IC17dk-mF18 (Lch) organism synthetic construct constructo sintético DIQMTQSSSSFSVSLGDRVTITCKASEDIYNRLAWYQQKPGNAPRLLISGATSLETGVPSRFSGSGSGKDYTLSITSLQTEDVATYYCQQYWSTPYTFGGGTKLEVKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 444 AA PAT source 1..444 mol_type protein note IC17-SG105 (Hch) IC17-SG105 (Hch) organism synthetic construct constructo sintético QVQLQQSGPQLVRPGASVNISCKASGYSFTSYWMHWVNQRPGQGLEWIGMIDPSYSETRLNQKFKDKATLTVDKSSSTAYMQLSSPTSEDSAVYYCALYGNYFDYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELRRGPKVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 214 AA PAT source 1..214 mol_type protein note IC17-SG105 (Lch) IC17-SG105 (Lch) organism synthetic construct constructo sintético DIQMTQSSSSFSVSLGDRVTITCKASEDIYNRLAWYQQKPGNAPRLLISGATSLETGVPSRFSGSGSGKDYTLSITSLQTEDVATYYCQQYWSTPYTFGGGTKLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 448 AA PAT source 1..448 mol_type protein note GC1008-F1332m (Hch) GC1008-F1332m (Hch) organism synthetic construct constructo sintético QVQLVQSGAEVKKPGSSVKVSCKASGYTFSSNVISWVRQAPGQGLEWMGGVIPIVDIANYAQRFKGRVTITADESTSTTYMELSSLRSEDTAVYYCASTLGLVLDAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELRRGPKVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 215 AA PAT source 1..215 mol_type protein note GC1008-F1332m (Lch) GC1008-F1332m (Lch) organism synthetic construct constructo sintético ETVLTQSPGTLSLSPGERATLSCRASQSLGSSYLAWYQQKPGQAPRLLIYGASSRAPGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYADSPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 444 AA PAT source 1..444 mol_type protein note 21D1-F1332m (Hch) 21D1-F1332m (Hch) organism synthetic construct constructo sintético QVQLVQSGAEVKKPGASVKVSCKASGYTFTDYNIHWVRQAPGQGLEWMGYIYPYDGETGYNQKFKSRVTMTTDTSTSTAYMELRSLRSDDTAVYYCARGYRWFAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELRRGPKVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 213 AA PAT source 1..213 mol_type protein note 21D1-F1332m (Lch) 21D1-F1332m (Lch) organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCRASSSVPYMHWFQQKPGKAPKSLIYATSNPAYGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQWDLNPPAFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 444 AA PAT source 1..444 mol_type protein note 3G9-mF18 (Hch) 3G9-mF18 (Hch) organism synthetic construct constructo sintético EVMLVESGGGLVKPGGSLKLSCAASGFTFSRYVMSWVRQTPEKRLEWVASISSGGRMYYPDTVKGRFTISRDSARNILYLQMSSLRSEDTAMYYCARGSIYDGYYVFPYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICTVKEVSKVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVEVHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNSAAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMITDFFPEDITVEWQWNGQPAENYKNTQPIMDTDGSYFVYSKLNVQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGK 215 AA PAT source 1..215 mol_type protein note 3G9-mF18 (Lch) 3G9-mF18 (Lch) organism synthetic construct constructo sintético QIVLTQSPAIMSASPGEKVTLTCSANSSVSSSYLYWYQQKSGSSPKLWIYSTSNLASGVPVRFSGSGSGTSFSLTISSMEAEDAASYFCHQWSTYPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 450 AA PAT source 1..450 mol_type protein note hT0947AE20-SG181 full H hT0947AE20-SG181 H completa organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFLFSREAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHQYWVMHFWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 215 AA PAT source 1..215 mol_type protein note hT0947AE20-SG181/191 full L hT0947AE20-SG181/191 L completa organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYEAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 450 AA PAT source 1..450 mol_type protein note hT0947AE27-SG181 full H hT0947AE27-SG181 H completa organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSNEAMNWIRQPPGKGLEWIGYIYTTGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHHYWVMHFWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 215 AA PAT source 1..215 mol_type protein note hT0947AE27-SG181/191 full L hT0947AE27-SG181/191 L completa organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQRISTYVAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 450 AA PAT source 1..450 mol_type protein note hT0947AE34-SG181 full H hT0947AE34-SG181 H completa organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSSEAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFDHHYWVMHAWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 215 AA PAT source 1..215 mol_type protein note hT0947AE34-SG181/191 full L hT0947AE34-SG181/191 L completa organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYLAWYQQKPGQPPKLLIYAASTLEYGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 450 AA PAT source 1..450 mol_type protein note hT0947AE37-SG181 full H hT0947AE37-SG181 H completa organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSSEAMNWIRQPPGKGLEWIGYIYVSGTTYRADWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHHYWVMHAWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 215 AA PAT source 1..215 mol_type protein note hT0947AE37-SG181/191 full L hT0947AE37-SG181/191 L completa organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASESISTYLAWYQQKPGQPPKLLIYAASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDGDSVIFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 450 AA PAT source 1..450 mol_type protein note hT0947AE20-SG191 full H hT0947AE20-SG191 H completa organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFLFSREAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHQYWVMHFWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVLHEALHAHYTRKELSLSP 450 AA PAT source 1..450 mol_type protein note hT0947AE27-SG191 full H hT0947AE27-SG191 H completa organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSNEAMNWIRQPPGKGLEWIGYIYTTGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHHYWVMHFWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVLHEALHAHYTRKELSLSP 450 AA PAT source 1..450 mol_type protein note hT0947AE34-SG191 full H hT0947AE34-SG191 H completa organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSSEAMNWIRQPPGKGLEWIGYIYTSGTTYRANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFDHHYWVMHAWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVLHEALHAHYTRKELSLSP 450 AA PAT source 1..450 mol_type protein note hT0947AE37-SG191 full H hT0947AE37-SG191 H completa organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFHFSSEAMNWIRQPPGKGLEWIGYIYVSGTTYRADWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGWHIFGHHYWVMHAWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVLHEALHAHYTRKELSLSP 390 AA PAT source 1..390 mol_type protein note human TGF-beta 1 preproprotein preproproteína de TGF-beta 1 humano organism Homo sapiens Homo sapiens MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 1173 RNA PAT source 1..1173 mol_type mRNA note nucleic acid sequence encoding human TGF-beta 1 secuencia de ácido nucleico que codifica TGF-beta 1 humano organism Homo sapiens Homo sapiens atgccgccctccgggctgcggctgctgccgctgctgctaccgctgctgtggctactggtgctgacgcctggccggccggccgcgggactatccacctgcaagactatcgacatggagctggtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgccagccccccgagccagggggaggtgccgcccggcccgctgcccgaggccgtgctcgccctgtacaacagcacccgcgaccgggtggccggggagagtgcagaaccggagcccgagcctgaggccgactactacgccaaggaggtcacccgcgtgctaatggtggaaacccacaacgaaatctatgacaagttcaagcagagtacacacagcatatatatgttcttcaacacatcagagctccgagaagcggtacctgaacccgtgttgctctcccgggcagagctgcgtctgctgaggctcaagttaaaagtggagcagcacgtggagctgtaccagaaatacagcaacaattcctggcgatacctcagcaaccggctgctggcacccagcgactcgccagagtggttatcttttgatgtcaccggagttgtgcggcagtggttgagccgtggaggggaaattgagggctttcgccttagcgcccactgctcctgtgacagcagggataacacactgcaagtggacatcaacgggttcactaccggccgccgaggtgacctggccaccattcatggcatgaaccggcctttcctgcttctcatggccaccccgctggagagggcccagcatctgcaaagctcccggcaccgccgagccctggacaccaactattgcttcagctccacggagaagaactgctgcgtgcggcagctgtacattgacttccgcaaggacctcggctggaagtggatccacgagcccaagggctaccatgccaacttctgcctcgggccctgcccctacatttggagcctggacacgcagtacagcaaggtcctggccctgtacaaccagcataacccgggcgcctcggcggcgccgtgctgcgtgccgcaggcgctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctgtccaacatgatcgtgcgctcctgcaagtgcagctga 390 AA PAT source 1..390 mol_type protein note mouse TGF-beta 1 preproprotein preproproteína de TGF-beta 1 de ratón organism Mus musculus Mus musculus MPPSGLRLLPLLLPLPWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVDRNNAIYEKTKDISHSIYMFFNTSDIREAVPEPPLLSRAELRLQRLKSSVEQHVELYQKYSNNSWRYLGNRLLTPTDTPEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNKLHVEINGISPKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 1173 RNA PAT source 1..1173 mol_type mRNA note nucleic acid sequence encoding mouse TGF-beta 1 secuencia de ácido nucleico que codifica TGF-beta 1 de ratón organism Mus musculus Mus musculus atgccgccctcggggctgcggctactgccgcttctgctcccactcccgtggcttctagtgctgacgcccgggaggccagccgcgggactctccacctgcaagaccatcgacatggagctggtgaaacggaagcgcatcgaagccatccgtggccagatcctgtccaaactaaggctcgccagtcccccaagccagggggaggtaccgcccggcccgctgcccgaggcggtgctcgctttgtacaacagcacccgcgaccgggtggcaggcgagagcgccgacccagagccggagcccgaagcggactactatgctaaagaggtcacccgcgtgctaatggtggaccgcaacaacgccatctatgagaaaaccaaagacatctcacacagtatatatatgttcttcaatacgtcagacattcgggaagcagtgcccgaacccccattgctgtcccgtgcagagctgcgcttgcagagattaaaatcaagtgtggagcaacatgtggaactctaccagaaatatagcaacaattcctggcgttaccttggtaaccggctgctgacccccactgatacgcctgagtggctgtcttttgacgtcactggagttgtacggcagtggctgaaccaaggagacggaatacagggctttcgattcagcgctcactgctcttgtgacagcaaagataacaaactccacgtggaaatcaacgggatcagccccaaacgtcggggcgacctgggcaccatccatgacatgaaccggcccttcctgctcctcatggccacccccctggaaagggcccagcacctgcacagctcacggcaccggagagccctggataccaactattgcttcagctccacagagaagaactgctgtgtgcggcagctgtacattgactttaggaaggacctgggttggaagtggatccacgagcccaagggctaccatgccaacttctgtctgggaccctgcccctatatttggagcctggacacacagtacagcaaggtccttgccctctacaaccaacacaacccgggcgcttcggcgtcaccgtgctgcgtgccgcaggctttggagccactgcccatcgtctactacgtgggtcgcaagcccaaggtggagcagttgtccaacatgattgtgcgctcctgcaagtgcagctga 390 AA PAT source 1..390 mol_type protein note cynomolgus monkey TGF-beta 1 preproprotein preproproteína de TGF-beta 1 de Macaca fascicularis organism Macaca fascicularis Macaca fascicularis MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSKDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 1173 RNA PAT source 1..1173 mol_type mRNA note nucleic acid sequence encoding cynomolgus monkey TGF-beta 1 secuencia de ácido nucleico que codifica TGF-beta 1 de Macaca fascicularis organism Macaca fascicularis Macaca fascicularis atgccgccctccgggctgcggctgctgccgctgctgctaccgctgctgtggctactggtgctgacgcctggccggccggccgccggactatccacctgcaagactatcgacatggagctggtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgccagccccccgagccagggggaggtgccgcccggcccgctgcccgaggccgtgctcgccctgtacaacagcacccgcgaccgggtggccggggagagtgcggagccggaacccgaaccggaggccgactactacgccaaggaggtcacccgcgtgctaatggtggaaacccacaacgaaatctatgacaagttcaagcagagcacacacagcatatatatgttcttcaacacatcagagctccgagaagcagtacctgaacctgtgttgctctcccgggcagagctgcgtctgctgaggctcaagttaaaagtggagcagcatgtggagctgtaccagaaatacagcaacaattcctggcgatacctcagcaaccggctgctggcgcccagcgactcgccggagtggttgtcttttgatgtcaccggagttgtgcggcagtggttgagccgcggaggggaaattgagggctttcgccttagcgcccactgctcctgtgacagcaaagataacacactgcaagtggacatcaacgggttcactaccggccgccgaggtgacctggccaccattcatggcatgaaccggcctttcctgcttctcatggccaccccgctggagagggcccaacatctgcaaagctcccggcaccgccgagccctggacaccaactactgcttcagctccacggagaagaactgctgcgtgcggcagctgtatattgacttccgcaaggacctcggctggaagtggatccacgagcccaagggctaccatgccaacttctgcctgggaccctgcccctacatttggagcctggacacgcagtacagcaaggtcctggccctgtacaaccagcataacccgggcgcctcggcggcgccgtgctgcgtgccgcaggcgctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctgtccaacatgatcgtgcgctcctgcaaatgcagctga 387 AA PAT source 1..387 mol_type protein note flag-tagged human latent TGF-beta 1 TGF-beta 1 latente humano etiquetado flag organism synthetic construct constructo sintético MKWVTFLLLLFISGSAFSDYKDDDDKLSTSKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 10 AA PAT source 1..10 mol_type protein note RGD peptide Péptido RGD organism synthetic construct constructo sintético GRRGDLATIH 10 AA PAT source 1..10 mol_type protein note RGE control peptide péptido de control RGE organism synthetic construct constructo sintético GRRGELATIH 450 AA PAT source 1..450 mol_type protein note hT0947AE04-SG181 (Hch) hT0947AE04-SG181 (Hch) organism synthetic construct constructo sintético QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMNWIRQPPGKGLEWIGYIYTSGTTYHANWARGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGTFIWDYYYWVMDLWGPGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELRRGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP 215 AA PAT source 1..215 mol_type protein note hT0947AE04-SG181 (Lch) hT0947AE04-SG181 (Lch) organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCQASQSISTYLAWYQQKPGQPPKLLIYKASTLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQSYSDADSVGFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 330 AA PAT source 1..330 mol_type protein note wild type IgG1 Fc region región Fc de IgG1 de tipo silvestre organism synthetic construct constructo sintético ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 326 AA PAT source 1..326 mol_type protein note wild type IgG2 Fc region región Fc de IgG2 de tipo silvestre organism synthetic construct constructo sintético ASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 377 AA PAT source 1..377 mol_type protein note wild type IgG3 Fc region región Fc de IgG3 de tipo silvestre organism synthetic construct constructo sintético ASTKGPSVFPLAPCSRSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYTCNVNHKPSNTKVDKRVELKTPLGDTTHTCPRCPEPKSCDTPPPCPRCPEPKSCDTPPPCPRCPEPKSCDTPPPCPRCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFKWYVDGVEVHNAKTKPREEQYNSTFRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESSGQPENNYNTTPPMLDSDGSFFLYSKLTVDKSRWQQGNIFSCSVMHEALHNRFTQKSLSLSPGK 327 AA PAT source 1..327 mol_type protein note wild type IgG4 Fc region región Fc de IgG4 de tipo silvestre organism synthetic construct constructo sintético ASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK