IB UVK29133PCT EP 23 178 486.9 2023-06-09 Universität zu Köln Universität zu Köln Universitaet zu Koeln Broadly neutralizing antibodies targeting the CD4 binding site on HIV Env Anticuerpos ampliamente neutralizantes dirigidos al sitio de unión de CD4 en la Env del VIH 41 19 AA PAT source 1..19 mol_type protein organism synthetic construct constructo sintético DSFTVYRPRLSAYFIGEFN 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético VNIFRGAV 15 AA PAT source 1..15 mol_type protein organism synthetic construct constructo sintético AWDKNVDDNPWRLDS 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético QDVGWA 000 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético QVFDS 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético GYSFRDYR 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético MQPRYGAV 20 AA PAT source 1..20 mol_type protein organism synthetic construct constructo sintético VTHKLYDGEDASDLTWRLDP 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético QDITNA 000 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético QHYEF 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético AYFIGEFN 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético VNIFRGAV 15 AA PAT source 1..15 mol_type protein organism synthetic construct constructo sintético AWDKNVDDNPWRLDS 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético QDVGWA 000 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético QVFES 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético GYTFRDYR 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético LHPAYGAV 20 AA PAT source 1..20 mol_type protein organism synthetic construct constructo sintético VTHKLYDGEDASDLTWRLDP 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético QDITNA 000 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético QHYEF 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético GYSFRDYR 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético IQPRYGAV 20 AA PAT source 1..20 mol_type protein organism synthetic construct constructo sintético VTHKLYDGEDASDLAWRLDP 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético QDITNA 000 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético QHYEF 133 AA PAT source 1..133 mol_type protein organism synthetic construct constructo sintético SVRLDQSGTAVKKPGASVRVSCRAPDSFTVYRPRLSAYFIGEFNIHWLRQAPGQGLEWLGFVNIFRGAVKYSSRFQGRITITRDTSSETSYLDLGALKADDTATYYCAWDKNVDDNPWRLDSWGQGTLVIVSS 103 AA PAT source 1..103 mol_type protein organism synthetic construct constructo sintético YIQVTQSPSSLSASIGDTITVACEVSQDVGWAVNWYHQRPGRPPYNLIYTAHNLAPGVASRFRGSRVGTYFTLTINNLLPEDVGTYYCQVFDSFAPGGTRVDL 137 AA PAT source 1..137 mol_type protein organism synthetic construct constructo sintético HVQLWQSGAEVKKPGASVKISCSAWGFGTTSGYSFRDYRVHWVRHIAGQGFQWMGHMQPRYGAVNYARQFQGRITMTREVSFDASGGTAYMELRSLRSDDTAVYYCVTHKLYDGEDASDLTWRLDPWGQGTRVIVSS 104 AA PAT source 1..104 mol_type protein organism synthetic construct constructo sintético GVHLTQSPASLSASVGDRVTFTCQASQDITNAINWYQLRPGKTPKLMIHDGSTLRRGVPSRFAGSGFGTKFTFTIDNLQPEDLATYFCQHYEFFPPVGTQVELN 133 AA PAT source 1..133 mol_type protein organism synthetic construct constructo sintético SVRLDQSGTAVKKPGASVRVSCRAPDSFTVYRPRLSAYFIGEFNIHWLRQAPGQGLEWLGFVNIFRGAVKYSSAFRGRITITRDTSLETSYLDLGALKPDDTATYFCAWDKNVDDNPWRLDSWGQGTLVVVSS 104 AA PAT source 1..104 mol_type protein organism synthetic construct constructo sintético YIQVTQSPSSLSASVGDTITVACQVSQDVGWAVNWYHQRPGRPPYNLIYTTSNLAPGVASRFRGTRVATYFTLTINNLLPEDVGTYYCQVFESFAPGGTRVDLR 137 AA PAT source 1..137 mol_type protein organism synthetic construct constructo sintético HVQLWQSGAEVKKPGASVKISCSAWGFGTRSGYTFRDYRIHWVRQVPRQGFEWMGHLHPAYGAVNYARQFQGRIIMTREVSFDGSGGTVYMELRSLRSDDTATYYCVTHKLYDGEDASDLTWRLDPWGQGTRVTVSS 104 AA PAT source 1..104 mol_type protein organism synthetic construct constructo sintético GVSLTQSPASLCASVGDRVTFTCQASQDITNAINWYQLRPGKTPKLMIHDGSTLRRGVPSRFAGSGFGTRFTFTIDNLQPEDLATYFCQHYEFFPPAGTQVDFN 137 AA PAT source 1..137 mol_type protein organism synthetic construct constructo sintético HVQLWQSGAEVKKPGASVKISCAAWGFGTTSGYSFRDYRIHWVRQVPGQGFQWMGHIQPRYGAVNYAHQFQGRITMTREVSFDASGGTAYMELRSLRSDDTATYYCVTHKLYDGEDASDLAWRLDPWGQGTRVTVSS 104 AA PAT source 1..104 mol_type protein organism synthetic construct constructo sintético GVHLTQSPASLSASVGDRVTFTCQASQDITNAINWYQLRPGKTPKLMIHDGSTLRRGVPSRFAGGGFGTKFTFTIDNLQPEDLATYFCQHYEFFPPAGTQVELN 104 AA PAT source 1..104 mol_type protein organism synthetic construct constructo sintético YIQVTQSPSSLSASIGDTITVACEVSQDVGWAVNWYHQRPGRPPYNLIYTAHNLAPGVASRFRGSRVGTYFTLTINNLLPEDVGTYYCQVFDSFAPGGTRVDLR