IB 4525.119PC02 US 63/512,546 2023-07-07 Kriya Therapeutics, Inc. Michele Stone ADMINISTRACIÓN PERIOCULAR DE VECTORES VIRALES ADENOASOCIADOS (AAV) PARA TRATAR PATOLOGÍAS OFTÁLMICAS 155 5 AA PAT REGION 1..5 note Variable Heavy Chain CDR1 source 1..5 mol_type protein organism synthetic construct SYGMH 17 AA PAT REGION 1..17 note Variable Heavy Chain CDR2 source 1..17 mol_type protein organism synthetic construct IIWFDGSSTYYADSVRG 9 AA PAT REGION 1..9 note Variable Heavy Chain CDR3 source 1..9 mol_type protein organism synthetic construct ELGRRYFDL 11 AA PAT REGION 1..11 note Variable Light Chain CDR1 source 1..11 mol_type protein organism synthetic construct RASQSVSSYLA 7 AA PAT REGION 1..7 note Variable Light Chain CDR2 source 1..7 mol_type protein organism synthetic construct DASKRAT 10 AA PAT REGION 1..10 note Variable Light Chain CDR3 source 1..10 mol_type protein organism synthetic construct QQRSKWPPWT 17 AA PAT REGION 1..17 note Variable Heavy Chain CDR2 source 1..17 mol_type protein organism synthetic construct IIWFDGSSKYYGDSVKG 7 AA PAT REGION 1..7 note Variable Light Chain CDR2 source 1..7 mol_type protein organism synthetic construct DASNRAT 15 DNA PAT misc_feature 1..15 note teprotumumab (anti-IGF-1R #1) VH CDR 1 source 1..15 mol_type other DNA organism synthetic construct tcctacgggatgcat 51 DNA PAT misc_feature 1..51 note teprotumumab (anti-IGF-1R #1) VH CDR 2 source 1..51 mol_type other DNA organism synthetic construct atcatttggttcgacggatcttcaacttattacgccgatagtgttcgaggg 27 DNA PAT misc_feature 1..27 note teprotumumab (anti-IGF-1R #1) VH CDR 3 source 1..27 mol_type other DNA organism synthetic construct gagctgggccgccggtattttgacctt 15 DNA PAT misc_feature 1..15 note Modified teprotumumab (anti-IGF-1R #2) VH CDR 1 source 1..15 mol_type other DNA organism synthetic construct tcctatgggatgcat 51 DNA PAT misc_feature 1..51 note Modified teprotumumab (anti-IGF-1R #2) VH CDR 2 source 1..51 mol_type other DNA organism synthetic construct atcatttggtttgatggatcttcaacttattatgctgatagtgttagaggg 27 DNA PAT misc_feature 1..27 note Modified teprotumumab (anti-IGF-1R #2) VH CDR 3 source 1..27 mol_type other DNA organism synthetic construct gagctgggccgcagatattttgacctt 51 DNA PAT misc_feature 1..51 note Modified teprotumumab (anti-IGF-1R #3) VH CDR 2 source 1..51 mol_type other DNA organism synthetic construct atcatttggtttgatggatcttcaacttattatgctgatagtgttaggggg 27 DNA PAT misc_feature 1..27 note Modified teprotumumab (anti-IGF-1R #3) VH CDR 3 source 1..27 mol_type other DNA organism synthetic construct gagctgggcagaaggtattttgacctt 33 DNA PAT misc_feature 1..33 note teprotumumab (anti-IGF-1R #1) VL CDR 1 source 1..33 mol_type other DNA organism synthetic construct agggcctcccagtctgtttcaagttatctggct 21 DNA PAT misc_feature 1..21 note teprotumumab (anti-IGF-1R #1) VL CDR 2 source 1..21 mol_type other DNA organism synthetic construct gacgcaagcaaacgagccacc 30 DNA PAT misc_feature 1..30 note teprotumumab (anti-IGF-1R #1) VL CDR 3 source 1..30 mol_type other DNA organism synthetic construct cagcagcggagtaagtggccaccctggaca 21 DNA PAT misc_feature 1..21 note Modified teprotumumab (anti-IGF-1R #2) VL CDR 2 source 1..21 mol_type other DNA organism synthetic construct gatgcaagcaaaagggccaca 30 DNA PAT misc_feature 1..30 note Modified teprotumumab (anti-IGF-1R #2) VL CDR 3 source 1..30 mol_type other DNA organism synthetic construct cagcagcggagtaagtggccaccctggaca 21 DNA PAT misc_feature 1..21 note Modified teprotumumab (anti-IGF-1R #3) VL CDR 2 source 1..21 mol_type other DNA organism synthetic construct gatgcaagcaaaagagccaca 30 DNA PAT misc_feature 1..30 note Modified teprotumumab (anti-IGF-1R #3) VL CDR 3 source 1..30 mol_type other DNA organism synthetic construct cagcagagaagtaagtggccaccctggaca 354 DNA PAT misc_feature 1..354 note teprotumumab (anti-IGF-1R #1) VH source 1..354 mol_type other DNA organism synthetic construct caggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctca 354 DNA PAT misc_feature 1..354 note Modified teprotumumab (anti-IGF-1R #2) VH source 1..354 mol_type other DNA organism synthetic construct caggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctca 354 DNA PAT misc_feature 1..354 note Modified teprotumumab (anti-IGF-1R #3) VH source 1..354 mol_type other DNA organism synthetic construct caggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctca 118 AA PAT REGION 1..118 note Variable Heavy Chain source 1..118 mol_type protein organism synthetic construct QVELVESGGGVVQPGRSQRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAIIWFDGSSTYYADSVRGRFTISRDNSKNTLYLQMNSLRAEDTAVYFCARELGRRYFDLWGRGTLVSVSS 118 AA PAT REGION 1..118 note Variable Heavy Chain source 1..118 mol_type protein organism synthetic construct QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWMAIIWFDGSSKYYGDSVKGRFTISRDNSKNTLYLQMNSLRADDTAVYYCARELGRRYFDLWGRGTLVTVSS 324 DNA PAT misc_feature 1..324 note teprotumumab (anti-IGF-1R #1) VL source 1..324 mol_type other DNA organism synthetic construct gagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaag 324 DNA PAT misc_feature 1..324 note Modified teprotumumab (anti-IGF-1R #2) VL source 1..324 mol_type other DNA organism synthetic construct gagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaag 324 DNA PAT misc_feature 1..324 note Modified teprotumumab (anti-IGF-1R #3) VL source 1..324 mol_type other DNA organism synthetic construct gagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaag 108 AA PAT REGION 1..108 note Variable Light Chain source 1..108 mol_type protein organism synthetic construct EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASKRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSKWPPWTFGQGTKVESK 108 AA PAT REGION 1..108 note Variable Light Chain source 1..108 mol_type protein organism synthetic construct EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSKWPPWTFGQGTKVEIK 321 DNA PAT misc_feature 1..321 note LC Constant #1 source 1..321 mol_type other DNA organism synthetic construct agaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgt 321 DNA PAT misc_feature 1..321 note LC Constant #2 source 1..321 mol_type other DNA organism synthetic construct agaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgt 321 DNA PAT misc_feature 1..321 note LC Constant #3 source 1..321 mol_type other DNA organism synthetic construct agaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgt 990 DNA PAT misc_feature 1..990 note HC Constant #1 source 1..990 mol_type other DNA organism synthetic construct gcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaa 990 DNA PAT misc_feature 1..990 note HC Constant #2 source 1..990 mol_type other DNA organism synthetic construct gcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaa 990 DNA PAT misc_feature 1..990 note HC Constant #3 source 1..990 mol_type other DNA organism synthetic construct gcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaa 1398 DNA PAT misc_feature 1..1398 note HC #1 source 1..1398 mol_type other DNA organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaa 1398 DNA PAT misc_feature 1..1398 note HC #2 source 1..1398 mol_type other DNA organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaa 1398 DNA PAT misc_feature 1..1398 note HC #3 source 1..1398 mol_type other DNA organism synthetic construct atgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaa 448 AA PAT REGION 1..448 note Heavy Chain Amino Acid Sequence source 1..448 mol_type protein organism synthetic construct QVELVESGGGVVQPGRSQRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAIIWFDGSSTYYADSVRGRFTISRDNSKNTLYLQMNSLRAEDTAVYFCARELGRRYFDLWGRGTLVSVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 54 DNA PAT misc_feature 1..54 note signal peptide IL-10 source 1..54 mol_type other DNA organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggct 18 AA PAT REGION 1..18 note signal peptide IL-10 source 1..18 mol_type protein organism synthetic construct MHSSALLCCLVLLTGVRA 705 DNA PAT misc_feature 1..705 note LC #1 source 1..705 mol_type other DNA organism synthetic construct atgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgt 705 DNA PAT misc_feature 1..705 note LC #2 source 1..705 mol_type other DNA organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgt 705 DNA PAT misc_feature 1..705 note LC #3 source 1..705 mol_type other DNA organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgt 215 AA PAT REGION 1..215 note Light Chain Amino Acid Sequence source 1..215 mol_type protein organism synthetic construct EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASKRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSKWPPWTFGQGTKVESKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 60 DNA PAT misc_feature 1..60 note signal peptide IL-2 source 1..60 mol_type other DNA organism synthetic construct atgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactct 20 AA PAT REGION 1..20 note signal peptide IL-2 source 1..20 mol_type protein organism synthetic construct MYRMQLLSCIALSLALVTNS 2202 DNA PAT misc_feature 1..2202 note ORF #1 source 1..2202 mol_type other DNA organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttag 2202 DNA PAT misc_feature 1..2202 note ORF #2 source 1..2202 mol_type other DNA organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 1401 DNA PAT misc_feature 1..1401 note ORF #3 source 1..1401 mol_type other DNA organism synthetic construct atgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 708 DNA PAT misc_feature 1..708 note ORF #4 source 1..708 mol_type other DNA organism synthetic construct atgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttag 1401 DNA PAT misc_feature 1..1401 note ORF #5 source 1..1401 mol_type other DNA organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaatag 708 DNA PAT misc_feature 1..708 note ORF #6 source 1..708 mol_type other DNA organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 1401 DNA PAT misc_feature 1..1401 note ORF #7 source 1..1401 mol_type other DNA organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 1401 DNA PAT misc_feature 1..1401 note ORF #8 source 1..1401 mol_type other DNA organism synthetic construct atgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 1401 DNA PAT misc_feature 1..1401 note ORF #9 source 1..1401 mol_type other DNA organism synthetic construct atgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 708 DNA PAT misc_feature 1..708 note ORF #10 source 1..708 mol_type other DNA organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 708 DNA PAT misc_feature 1..708 note ORF #11 source 1..708 mol_type other DNA organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 2694 DNA PAT misc_feature 1..2694 note ORF #12 source 1..2694 mol_type other DNA organism synthetic construct atgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaatag 2700 DNA PAT misc_feature 1..2700 note ORF #13 source 1..2700 mol_type other DNA organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcaccggcaaatagcaattga 2211 DNA PAT misc_feature 1..2211 note ORF #14 source 1..2211 mol_type other DNA organism synthetic construct atgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttag 2694 DNA PAT misc_feature 1..2694 note ORF #15 source 1..2694 mol_type other DNA organism synthetic construct atgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatag 4479 DNA PAT misc_feature 1..4479 note EC #1 source 1..4479 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4799 DNA PAT misc_feature 1..4799 note EC #2 source 1..4799 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaatagtgacaattgaataaaagatctttattttcattagatctgtgtgttggttttttgtgtggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4288 DNA PAT misc_feature 1..4288 note EC #3 source 1..4288 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctcgtttagtgaaccgtcagatcgcctggagaaggaactgaaaaaccagaaagttaactggtaagtttagtctttttgtcttttatttcaggtcccggatccggtggtggtgcaaatcaaagaactgctcctcagtggatgttgcctttacttctaggcctgtacggaagtgttacttctgctctaaaagctgcggaattgtagcccggttaattaagccaccatgtaccggatgcagctgctcagctgcatcgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctatcgcctggcgaaagagcgacgctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgacgcaagcaaacgagccaccgggatccccgctcgtttctccggttctggcagcggaacagattttactcttaccatttcctcactcgagcctgaagacttcgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctccgatgaacagctgaaatcgggtacggcttcagtggtttgtctgctcaataacttctacccgagggaggccaaggtgcagtggaaggtcgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggccgattacgagaaacacaaggtgtacgcttgcgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaatcgcggcgagtgttaggcatgcctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattctcagaactaacatacgctctccatcaaaacaaaacgaaacaaaacaaactagcaaaataggctgtccccagtgcaagtgcaggtgccagaacatttctctatcgaaggatctgcgatcgctccggtgcccgtcagtgggcagagcgcacatcgcccacagtccccgagaagttggggggaggggtcggcaattgaaccggtgcctagagaaggtggcgcggggtaaactgggaaagtgatgtcgtgtactggctccgcctttttcccgagggtgggggagaaccgtatataagtgcagtagtcgccgtgaacgttctttttcgcaacgggtttgccgccagaacacagctgaagcttcgaggggctcgcatctctccttcacgcgcccgccgccctacctgaggccgccatccacgccggttgagtcgcgttctgccgcctcccgcctgtggtgcctcctgaactgcgtccgccgtctaggtaagtttaaagctcaggtcgagaccgggcctttgtccggcgctcccttggagcctacctagactcagccggctctccacgctttgcctgaccctgcttgctcaactctacgtctttgtttcgttttctgttctgcgccgttacagatcgaagttggtcgtgaggcactgggcaggtaagtatcaaggttacaagacaggtttaaggagaccaatagaaactgggcttgtcgagacagagaagactcttgcgtttctgataggcacctattggtcttactgacatccactttgcctttctctccacaggtgtccactcccagttcaattacagctcttaaggctagtttaaaccaccatgcacagctccgccctgctctgctgtttggtgcttctgaccggcgtccgggctcaggttgagttagtggaatctggagggggtgtagtgcaacccggcagatcacagaggctgagttgcgcagcgtcgggattcacatttagctcctacgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggttcgacggatcttcaacttattacgccgatagtgttcgagggcgttttacgataagccgggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagccgtgtacttctgtgctagggagctgggccgccggtattttgacctttggggcagaggaactctcgtcagcgtatcctcagcaagtaccaaggggccaagcgtgttcccgctggccccctcttccaaatcgacatcaggtggcaccgcggctctgggatgcctcgttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacgtctggcgtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttaccgtgccttctagctccctgggaactcagacctacatctgtaacgtaaatcataaaccaagcaacacaaaggtggacaagaaagtcgagcccaagtcttgcgataaaacccacacttgtccgccttgcccagcccccgagctactcgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggacgcccgaagtgacctgtgtcgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtacgtggatggcgtcgaggtgcacaacgctaagactaaaccgcgcgaagagcagtataatagcacataccgagtcgtgtcggttctgaccgtgcttcaccaagactggctcaacggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctatcgaaaaaactatttcaaaggctaaagggcagccacgtgagccccaggtctacaccctgcctccatcccgggacgaattaacaaagaaccaggtgagtctcacgtgcctggttaaaggtttttatcccagcgatatcgccgtggagtgggagtctaacggccaaccggaaaataactacaagaccacacctccagtcttggactccgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttccgttatgcatgaggcgctacacaaccattatacccagaagtctctctcgctgtcacccggcaaatagcctaggaataaaagatctttattttcattagatctgtgtgttggttttttgtgtgctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4479 DNA PAT misc_feature 1..4479 note EC #4 source 1..4479 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4795 DNA PAT misc_feature 1..4795 note EC #5 source 1..4795 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcaccggcaaatagcaattgaataaaagatctttattttcattagatctgtgtgttggttttttgtgtggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4288 DNA PAT misc_feature 1..4288 note EC #6 source 1..4288 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctcgtttagtgaaccgtcagatcgcctggagaaggaactgaaaaaccagaaagttaactggtaagtttagtctttttgtcttttatttcaggtcccggatccggtggtggtgcaaatcaaagaactgctcctcagtggatgttgcctttacttctaggcctgtacggaagtgttacttctgctctaaaagctgcggaattgtagcccggttaattaagccaccatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcatgcctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattctcagaactaacatacgctctccatcaaaacaaaacgaaacaaaacaaactagcaaaataggctgtccccagtgcaagtgcaggtgccagaacatttctctatcgaaggatctgcgatcgctccggtgcccgtcagtgggcagagcgcacatcgcccacagtccccgagaagttggggggaggggtcggcaattgaaccggtgcctagagaaggtggcgcggggtaaactgggaaagtgatgtcgtgtactggctccgcctttttcccgagggtgggggagaaccgtatataagtgcagtagtcgccgtgaacgttctttttcgcaacgggtttgccgccagaacacagctgaagcttcgaggggctcgcatctctccttcacgcgcccgccgccctacctgaggccgccatccacgccggttgagtcgcgttctgccgcctcccgcctgtggtgcctcctgaactgcgtccgccgtctaggtaagtttaaagctcaggtcgagaccgggcctttgtccggcgctcccttggagcctacctagactcagccggctctccacgctttgcctgaccctgcttgctcaactctacgtctttgtttcgttttctgttctgcgccgttacagatcgaagttggtcgtgaggcactgggcaggtaagtatcaaggttacaagacaggtttaaggagaccaatagaaactgggcttgtcgagacagagaagactcttgcgtttctgataggcacctattggtcttactgacatccactttgcctttctctccacaggtgtccactcccagttcaattacagctcttaaggctagtttaaaccaccatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagcctaggaataaaagatctttattttcattagatctgtgtgttggttttttgtgtgctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4488 DNA PAT misc_feature 1..4488 note EC #7 source 1..4488 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4796 DNA PAT misc_feature 1..4796 note EC #8 source 1..4796 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcccctctccctcccccccccctaacgttactggccgaagccgcttggaataaggccggtgtgcgtttgtctatatgttattttccaccatattgccgtcttttggcaatgtgagggcccggaaacctggccctgtcttcttgacgagcattcctaggggtctttcccctctcgccaaaggaatgcaaggtctgttgaatgtcgtgaaggaagcagttcctctggaagcttcttgaagacaaacaacgtctgtagcgaccctttgcaggcagcggaaccccccacctggcgacaggtgcctctgcggccaaaagccacgtgtataagatacacctgcaaaggcggcacaaccccagtgccacgttgtgagttggatagttgtggaaagagtcaaatggctctcctcaagcgtattcaacaaggggctgaaggatgcccagaaggtaccccattgtatgggatctgatctggggcctcggtacacatgctttacatgtgtttagtcgaggttaaaaaaacgtctaggccccccgaaccacggggacgtggttttcctttgaaaaacacgatgataatatggccacaatgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagcaattgaataaaagatctttattttcattagatctgtgtgttggttttttgtgtggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 4288 DNA PAT misc_feature 1..4288 note EC #9 source 1..4288 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctcgtttagtgaaccgtcagatcgcctggagaaggaactgaaaaaccagaaagttaactggtaagtttagtctttttgtcttttatttcaggtcccggatccggtggtggtgcaaatcaaagaactgctcctcagtggatgttgcctttacttctaggcctgtacggaagtgttacttctgctctaaaagctgcggaattgtagcccggttaattaagccaccatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacctgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccaaggttgctgatatatgatgcaagcaaaagagccacagggatccctgctaggttctctggttctggctctggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagagaagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggctgcaccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagtctggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttaggcatgcctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattctcagaactaacatacgctctccatcaaaacaaaacgaaacaaaacaaactagcaaaataggctgtccccagtgcaagtgcaggtgccagaacatttctctatcgaaggatctgcgatcgctccggtgcccgtcagtgggcagagcgcacatcgcccacagtccccgagaagttggggggaggggtcggcaattgaaccggtgcctagagaaggtggcgcggggtaaactgggaaagtgatgtcgtgtactggctccgcctttttcccgagggtgggggagaaccgtatataagtgcagtagtcgccgtgaacgttctttttcgcaacgggtttgccgccagaacacagctgaagcttcgaggggctcgcatctctccttcacgcgcccgccgccctacctgaggccgccatccacgccggttgagtcgcgttctgccgcctcccgcctgtggtgcctcctgaactgcgtccgccgtctaggtaagtttaaagctcaggtcgagaccgggcctttgtccggcgctcccttggagcctacctagactcagccggctctccacgctttgcctgaccctgcttgctcaactctacgtctttgtttcgttttctgttctgcgccgttacagatcgaagttggtcgtgaggcactgggcaggtaagtatcaaggttacaagacaggtttaaggagaccaatagaaactgggcttgtcgagacagagaagactcttgcgtttctgataggcacctattggtcttactgacatccactttgcctttctctccacaggtgtccactcccagttcaattacagctcttaaggctagtttaaaccaccatgcacagctctgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgtgcagcaagtggattcacatttagctcctatgggatgcattgggtcagacaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagggggagatttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggcagaaggtattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccactggccccctcttccaaaagtacatcaggtggcacagcagctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccctgcagtccttcagtcctctggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccaccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccaagagaagagcagtataatagcacatacagggttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcctgcacctattgaaaaaactatttcaaaggctaaagggcagccaagagagccccaggtctacaccctgcctccatccagggatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcactacacaaccattatacccagaagtctctcagtctgtcacctggcaaatagcctaggaataaaagatctttattttcattagatctgtgtgttggttttttgtgtgctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 2977 DNA PAT misc_feature 1..2977 note AAV8.mCherry source 1..2977 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatgggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgcgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggctcgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgagaggagcgcggccgggggcggtgccacgcggtgcggggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtggggggggtgagcagggggtgtgggcgcggcggtcgggctgtaacccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtgcggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcgggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggtctagactctgctaaccatgttcatgccttcttctctttcctacagctcctgggcaacgtgctggttgttgtgctgtctcatcattttggcaaagaattcaagcttccagctagcgccaccatggtgagcaagggcgaggaggataacatggccatcatcaaggagttcatgcgcttcaaggtgcacatggagggctccgtgaacggccacgagttcgagatcgagggcgagggcgagggccgcccctacgagggcacccagaccgccaagctgaaggtgaccaagggtggccccctgcccttcgcctgggacatcctgtcccctcagttcatgtacggctccaaggcctacgtgaagcaccccgccgacatccccgactacttgaagctgtccttccccgagggcttcaagtgggagcgcgtgatgaacttcgaggacggcggcgtggtgaccgtgacccaggactcctccctgcaggacggcgagttcatctacaaggtgaagctgcgcggcaccaacttcccctccgacggccccgtaatgcagaagaagaccatgggctgggaggcctcctccgagcggatgtaccccgaggacggcgccctgaagggcgagatcaagcagaggctgaagctgaaggacggcggccactacgacgctgaggtcaagaccacctacaaggccaagaagcccgtgcagctgcccggcgcctacaacgtcaacatcaagttggacatcacctcccacaacgaggactacaccatcgtggaacagtacgaacgcgccgagggccgccactccaccggcggcatggacgagctgtacaagtagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcag 2215 DNA PAT misc_feature 1..2215 note AAV9.mCherry source 1..2215 mol_type other DNA organism synthetic construct ctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacctagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgacgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggcttgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagctagagcctctgctaaccatgttcatgccttcttctttttcctacagctcctgggcaacgtgctggttattgtgctgtctcatcattttggcaaagcggccgcaagcttgaattcatttaaatccagctagcgccaccatggtgagcaagggcgaggaggataacatggccatcatcaaggagttcatgcgcttcaaggtgcacatggagggctccgtgaacggccacgagttcgagatcgagggcgagggcgagggccgcccctacgagggcacccagaccgccaagctgaaggtgaccaagggtggccccctgcccttcgcctgggacatcctgtcccctcagttcatgtacggctccaaggcctacgtgaagcaccccgccgacatccccgactacttgaagctgtccttccccgagggcttcaagtgggagcgcgtgatgaacttcgaggacggcggcgtggtgaccgtgacccaggactcctccctgcaggacggcgagttcatctacaaggtgaagctgcgcggcaccaacttcccctccgacggccccgtaatgcagaagaagaccatgggctgggaggcctcctccgagcggatgtaccccgaggacggcgccctgaagggcgagatcaagcagaggctgaagctgaaggacggcggccactacgacgctgaggtcaagaccacctacaaggccaagaagcccgtgcagctgcccggcgcctacaacgtcaacatcaagttggacatcacctcccacaacgaggactacaccatcgtggaacagtacgaacgcgccgagggccgccactccaccggcggcatggacgagctgtacaagtagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcag 673 AA PAT REGION 1..673 note VRDN-01100 source 1..673 mol_type protein organism synthetic construct DVVMTQTPLSLPVSLGDPASISCRSSQSIVHSNVNTYLEWYLQKPGQSPRLLIYKVSNRFSGVPDRFSGSGAGTDFTLRISRVEAEDLGIYYCFQGSHVPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLVQSGAEVVKPGASVKLSCKASGYTFTSYWMHWVKQRPGQGLEWIGEINPSNGRTNYNQKFQGKATLTVDKSSSTAYMQLSSLTSEDSAVYYFARGRPDYYGSSKWYFDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 113 AA PAT REGION 1..113 note VRDN-01100 VL source 1..113 mol_type protein organism synthetic construct DVVMTQTPLSLPVSLGDPASISCRSSQSIVHSNVNTYLEWYLQKPGQSPRLLIYKVSNRFSGVPDRFSGSGAGTDFTLRISRVEAEDLGIYYCFQGSHVPPTFGGGTKLEIKR 124 AA PAT REGION 1..124 note VRDN-01100 VH source 1..124 mol_type protein organism synthetic construct QVQLVQSGAEVVKPGASVKLSCKASGYTFTSYWMHWVKQRPGQGLEWIGEINPSNGRTNYNQKFQGKATLTVDKSSSTAYMQLSSLTSEDSAVYYFARGRPDYYGSSKWYFDVWGQGTTVTVSS 665 AA PAT REGION 1..665 note VRDN-02700 source 1..665 mol_type protein organism synthetic construct DIVMTQSPLSLPVTPGEPASISCRSSQSIVHSNGNTYLQWYLQKPGQSPQLLIYKVSNRLYGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCFQGSHVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQESGPGLVKPSETLSLTCTVSGYSITGGYLWNWIRQPPGKGLEWIGYISYDGTNNYKPSLKDRVTISRDTSKNQFSLKLSSVTAADTAVYYCARYGRVFFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLYITREPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG 113 AA PAT REGION 1..113 note VRDN-02700 VL source 1..113 mol_type protein organism synthetic construct DIVMTQSPLSLPVTPGEPASISCRSSQSIVHSNGNTYLQWYLQKPGQSPQLLIYKVSNRLYGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCFQGSHVPWTFGQGTKVEIKR 117 AA PAT REGION 1..117 note VRDN-02700 VH source 1..117 mol_type protein organism synthetic construct QVQLQESGPGLVKPSETLSLTCTVSGYSITGGYLWNWIRQPPGKGLEWIGYISYDGTNNYKPSLKDRVTISRDTSKNQFSLKLSSVTAADTAVYYCARYGRVFFDYWGQGTLVTVSS 12 DNA PAT misc_feature 1..12 note Kozak Sequence source 1..12 mol_type other DNA organism synthetic construct gcggccgccatg 449 AA PAT REGION 1..449 note Lonigutamab HC source 1..449 mol_type protein organism synthetic construct QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYIHWVRQAPGQGLEWMGWIWPGDGSTKYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYFCASPMITPNYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG 119 AA PAT REGION 1..119 note Lonigutamab VH source 1..119 mol_type protein organism synthetic construct VQLVQSGAEVKKPGASVKVSCKASGYTFTSYYIHWVRQAPGQGLEWMGWIWPGDGSTKYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYFCASPMITPNYAMDYWGQGTLVTVSS 8 AA PAT REGION 1..8 note Lonigutamab VH - CDR1 source 1..8 mol_type protein organism synthetic construct GYTFTSYY 8 AA PAT REGION 1..8 note Lonigutamab VH - CDR2 source 1..8 mol_type protein organism synthetic construct IWPGDGST 13 AA PAT REGION 1..13 note Lonigutamab VH - CDR3 source 1..13 mol_type protein organism synthetic construct ASPMITPNYAMDY 214 AA PAT REGION 1..214 note Lonigutamab LC source 1..214 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQDISKYLNWYQQKPGKAPKLLIYYTSRLQSGVPSRFSGRGSGTDYSLTISSLQPEDFATYFCQQGSTLPYTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 107 AA PAT REGION 1..107 note Lonigutamab VL source 1..107 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQDISKYLNWYQQKPGKAPKLLIYYTSRLQSGVPSRFSGRGSGTDYSLTISSLQPEDFATYFCQQGSTLPYTFGGGTKVEIK 6 AA PAT REGION 1..6 note Lonigutamab VL - CDR1 source 1..6 mol_type protein organism synthetic construct QDISKY 9 AA PAT REGION 1..9 note Lonigutamab VL - CDR3 source 1..9 mol_type protein organism synthetic construct QQGSTLPYT 449 AA PAT REGION 1..449 note Tocilizumab HC source 1..449 mol_type protein organism synthetic construct QVQLQESGPGLVRPSQTLSLTCTVSGYSITSDHAWSWVRQPPGRGLEWIGYISYSGITTYNPSLKSRVTMLRDTSKNQFSLRLSSVTAADTAVYYCARSLARTTAMDYWGQGSLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 119 AA PAT REGION 1..119 note Tocilizumab VH source 1..119 mol_type protein organism synthetic construct QVQLQESGPGLVRPSQTLSLTCTVSGYSITSDHAWSWVRQPPGRGLEWIGYISYSGITTYNPSLKSRVTMLRDTSKNQFSLRLSSVTAADTAVYYCARSLARTTAMDYWGQGSLVTVSS 9 AA PAT REGION 1..9 note Tocilizumab VH - CDR1 source 1..9 mol_type protein organism synthetic construct GYSITSDHA 7 AA PAT REGION 1..7 note Tocilizumab VH - CDR2 source 1..7 mol_type protein organism synthetic construct ISYSGIT 12 AA PAT REGION 1..12 note Tocilizumab VH - CDR3 source 1..12 mol_type protein organism synthetic construct ARSLARTTAMDY 214 AA PAT REGION 1..214 note Tocilizumab LC source 1..214 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQDISSYLNWYQQKPGKAPKLLIYYTSRLHSGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQGNTLPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 107 AA PAT REGION 1..107 note Tocilizumab VL source 1..107 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQDISSYLNWYQQKPGKAPKLLIYYTSRLHSGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQGNTLPYTFGQGTKVEIK 6 AA PAT REGION 1..6 note Tocilizumab VL - CDR1 source 1..6 mol_type protein organism synthetic construct QDISSY 8 AA PAT REGION 1..8 note Tocilizumab VL - CDR3 source 1..8 mol_type protein organism synthetic construct QQGNTLPY 446 AA PAT REGION 1..446 note TOUR006 HC - IgG1 source 1..446 mol_type protein organism synthetic construct QVQLQQWGAGLLKPSETLSLTCAIYGGSFREYYWSWIRQPPGKGLEWIGEIFHSGSTNYNPSLKSRVNISVDTSKNQFSLKLTSVTAADTAVYYCAREELDDFDIWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 442 AA PAT REGION 1..442 note TOUR006 HC - IgG2 source 1..442 mol_type protein organism synthetic construct QVQLQQWGAGLLKPSETLSLTCAIYGGSFREYYWSWIRQPPGKGLEWIGEIFHSGSTNYNPSLKSRVNISVDTSKNQFSLKLTSVTAADTAVYYCAREELDDFDIWGQGTMVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 116 AA PAT REGION 1..116 note TOUR006 VH source 1..116 mol_type protein organism synthetic construct QVQLQQWGAGLLKPSETLSLTCAIYGGSFREYYWSWIRQPPGKGLEWIGEIFHSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCAREELDDFDIWGQGTMVTVSS 5 AA PAT REGION 1..5 note TOUR006 VH - CDR1 source 1..5 mol_type protein organism synthetic construct EYYWS 16 AA PAT REGION 1..16 note TOUR006 VH - CDR2 source 1..16 mol_type protein organism synthetic construct EIFHSGSTNYNPSLKS 8 AA PAT REGION 1..8 note TOUR006 VH - CDR3 source 1..8 mol_type protein organism synthetic construct EELDDFDI 214 AA PAT REGION 1..214 note TOUR006 LC -IgG1 source 1..214 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQGISSWLAWYQQKPEKAPKSLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYKSYPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 214 AA PAT REGION 1..214 note TOUR006 LC -IgG2 source 1..214 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQGISSWLAWYQQKPEKAPKSLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYKSYPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 107 AA PAT REGION 1..107 note TOUR006 VL source 1..107 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCRASQGISSWLAWYQQKPEKAPKSLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYKSYPRTFGQGTKVEIK 11 AA PAT REGION 1..11 note TOUR006 VL - CDR1 source 1..11 mol_type protein organism synthetic construct RASQGISSWLA 7 AA PAT REGION 1..7 note TOUR006 VL - CDR2 source 1..7 mol_type protein organism synthetic construct AASSLQS 9 AA PAT REGION 1..9 note TOUR006 VL - CDR3 source 1..9 mol_type protein organism synthetic construct QQYKSYPRT 118 AA PAT REGION 1..118 note LASN01 VH source 1..118 mol_type protein organism synthetic construct EVQLLESGGGLVQPGGSLRLSCAASGFTFSWYSMTWVRQAPGKGLEWVSSIVPYGDLTQYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKGPGWGSFDLWGRGTLVTVSS 5 AA PAT REGION 1..5 note LASN01 VH - CDR1 source 1..5 mol_type protein organism synthetic construct WYSMT 17 AA PAT REGION 1..17 note LASN01 VH - CDR2 source 1..17 mol_type protein organism synthetic construct SIVPYGDLTQYADSVKG 9 AA PAT REGION 1..9 note LASN01 VH - CDR3 source 1..9 mol_type protein organism synthetic construct GPGWGSFDL 107 AA PAT REGION 1..107 note LASN01 VL source 1..107 mol_type protein organism synthetic construct DIQMTQSPSSLSASVGDRVTITCQASQDINNYLNWYQQKPGKAPKLLIYDASNLQTGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQHESQSPTFGPGTKVDIK 11 AA PAT REGION 1..11 note LASN01 VL - CDR1 source 1..11 mol_type protein organism synthetic construct QASQDINNYLN 7 AA PAT REGION 1..7 note LASN01 VL - CDR2 source 1..7 mol_type protein organism synthetic construct DASNLQT 9 AA PAT REGION 1..9 note LASN01 VL - CDR3 source 1..9 mol_type protein organism synthetic construct QQHESQSPT 450 AA PAT REGION 1..450 note Batoclimab HC source 1..450 mol_type protein organism synthetic construct QLLLQESGPGLVKPSETLSLTCTVSGGSLSSSFSYWVWIRQPPGKGLEWIGTIYYSGNTYYNPSLKSRLTISVDTSKNHFSLKLSSVTAADTAVYYCARRAGILTGYLDSWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG 121 AA PAT REGION 1..121 note Batoclimab VH source 1..121 mol_type protein organism synthetic construct QLLLQESGPGLVKPSETLSLTCTVSGGSLSSSFSYWVWIRQPPGKGLEWIGTIYYSGNTYYNPSLKSRLTISVDTSKNHFSLKLSSVTAADTAVYYCARRAGILTGYLDSWGQGTLVTVSS 10 AA PAT REGION 1..10 note Batoclimab VH - CDR1 source 1..10 mol_type protein organism synthetic construct GGSLSSSFSY 7 AA PAT REGION 1..7 note Batoclimab VH - CDR2 source 1..7 mol_type protein organism synthetic construct IYYSGNT 13 AA PAT REGION 1..13 note Batoclimab VH - CDR3 source 1..13 mol_type protein organism synthetic construct ARRAGILTGYLDS 214 AA PAT REGION 1..214 note Batoclimab LC source 1..214 mol_type protein organism synthetic construct SYVLTQSPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSASNSGNTATLTISRVEAGDEADYYCQVWDSSSDHVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 90 AA PAT REGION 1..90 note Batoclimab VL source 1..90 mol_type protein organism synthetic construct SYVLTQSPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSASNSGNTATLTISRVEAGDEADYYCQVW 6 AA PAT REGION 1..6 note Batoclimab VL - CDR1 source 1..6 mol_type protein organism synthetic construct NIGSKS 11 AA PAT REGION 1..11 note Batoclimab VL - CDR3 source 1..11 mol_type protein organism synthetic construct QVWDSSSDHVV 450 AA PAT REGION 1..450 note IMVT-1402 HC source 1..450 mol_type protein organism synthetic construct EVQLLESGGGLVQPGGSLRLSCAASEFTFGSSVMTWVRQAPGKGLEWVSVISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKTPWWLRSPFFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG 121 AA PAT REGION 1..121 note IMVT-1402 VH source 1..121 mol_type protein organism synthetic construct EVQLLESGGGLVQPGGSLRLSCAASEFTFGSSVMTWVRQAPGKGLEWVSVISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKTPWWLRSPFFDYWGQGTLVTVSS 5 AA PAT REGION 1..5 note IMVT-1402 VH - CDR1 source 1..5 mol_type protein organism synthetic construct SSVMT 17 AA PAT REGION 1..17 note IMVT-1402 VH - CDR2 source 1..17 mol_type protein organism synthetic construct VISGSGGSTYYADSVKG 12 AA PAT REGION 1..12 note IMVT-1402 VH - CDR3 source 1..12 mol_type protein organism synthetic construct TPWWLRSPFFDY 214 AA PAT REGION 1..214 note IMVT-1402 LC source 1..214 mol_type protein organism synthetic construct SYVLTQPPSVSVAPGQTARITCGGSNIGSTSVHWYQQKPGQAPVLVVHDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVRDSSSDHVIFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 119 AA PAT REGION 1..119 note IMVT-1402 VL source 1..119 mol_type protein organism synthetic construct SYVLTQPPSVSVAPGQTARITCGGSNIGSTSVHWYQQKPGQAPVLVVHDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVRDSSSDHVIFGGGTKLTVLGQPKAAPSVTL 11 AA PAT REGION 1..11 note IMVT-1402 VL - CDR1 source 1..11 mol_type protein organism synthetic construct GGSNIGSTSVH 7 AA PAT REGION 1..7 note IMVT-1402 VL - CDR2 source 1..7 mol_type protein organism synthetic construct DDSDRPS 11 AA PAT REGION 1..11 note IMVT-1402 VL - CDR3 source 1..11 mol_type protein organism synthetic construct QVRDSSSDHVI 3728 DNA PAT source 1..3728 mol_type other DNA organism Synthetic construct misc_feature 1..3728 note EC #10 cagatctgcagctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttccttagtattaaacgcgtgtcgacctagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgacgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggcttgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagctagagcctctgctaaccatgttcatgccttcttctttttcctacagctcctgggcaacgtgctggttattgtgctgtctcatcattttggcaaagcggccgcaagcttgaattcatttaaatccagctagcgccaccatgcacagctccgccctgctctgctgtttggtgcttctgacaggagtcagggctcaggttgagttagtggaatctggagggggtgtagtgcaacctggcagatcacagaggctgagttgcgcagcaagtggattcacatttagctcctatgggatgcattgggtccgccaggcccctggcaagggtctagagtgggtggctatcatttggtttgatggatcttcaacttattatgctgatagtgttagagggcgctttactataagcagggacaactccaaaaataccctctatctgcaaatgaactctttgagagcagaagatacagctgtgtacttctgtgctagggagctgggccgcagatattttgacctttggggcagaggaactcttgtctctgtatcctcagcaagtaccaaggggccatctgtgttcccgctggccccctcttccaaaagtacatcaggtggcaccgcggctctgggatgcttggttaaggattactttcctgaaccagtgactgtcagctggaatagtggggccttgacttctggggtgcacacattccccgcagtccttcagtccagcggtctgtattcattatccagtgtggttacagtgccttctagctccctgggaactcagacctacatctgtaatgtaaatcataaaccaagcaacacaaaggtggacaagaaagttgagcccaagtcttgtgataaaacccacacttgtccgccttgcccagcccctgagctacttgggggcccttcagtttttctgttcccacccaagcctaaagacacattgatgattagtaggactcctgaagtgacctgtgttgtggtggatgtttcccatgaggacccagaagtaaagttcaattggtatgtggatggagttgaggtgcacaatgctaagactaaaccgagggaagagcagtataatagcacatacagagttgtgtcagttctgacagtgcttcaccaagactggctcaatggaaaggagtataaatgcaaggtatctaataaggccctgcccgcacctattgaaaaaactatttcaaaggctaaagggcagccaagggagccccaggtctacaccctgcctccatccagagatgaattaacaaagaaccaggtgagtctcacttgcctggttaaaggtttttatccctctgatattgctgtggagtgggagtctaatggccaaccagaaaataactacaagaccacacctccagtcttggactctgatggaagcttctttctttactcaaagctgactgtggacaaaagtagatggcagcaggggaatgtgttcagctgttctgttatgcatgaggcgctacacaaccattatacccagaagtctctcagtctgtcacctggcaaaagaaagagaaggagtggctcaggagcccctgtgaaacagaccctgaactttgacctcttgaagcttgctggggatgtggagtctaatcctggtccaatgtacagaatgcagctgctcagctgcattgccttgtcccttgctctggtgaccaactctgagattgtcttaacacaatcacccgcaactctgagtctaagtcctggagaaagagcaactctcagctgtagggcctcccagtctgtttcaagttatctggcttggtaccagcaaaagccaggacaggccccgcgcttgctgatatatgatgcaagcaaaagggccacagggatccccgctagattcagcggttctggcagcggaacagattttactcttaccatttcctcacttgagcctgaagactttgcagtgtactattgccagcagcggagtaagtggccaccctggacatttgggcaaggcaccaaagtagagagcaagagaactgtggccgcgccttctgtcttcatctttccaccctctgatgaacagctgaaatcaggtactgcttcagtggtttgtctgctcaataacttctacccaagggaggccaaggtgcagtggaaggttgacaatgcattgcagagcggaaacagtcaagagtctgtaacagaacaggattccaaagacagcacctattcactttccagtactctgaccttatctaaggctgattatgagaaacacaaggtgtatgcttgtgaagttacacatcaggggctgagctcccctgtgaccaaaagctttaataggggggagtgttagcaattgctgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcaggcatgctggggatgcggtgggctctatggagctcgagaggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 141 DNA PAT source 1..141 mol_type other DNA organism Synthetic construct misc_feature 1..141 note 5' ITR cagatctgcagctgcgcgctcgctcgctcactgaggccgcccgggcaaagcccgggcgtcgggcgacctttggtcgcccggcctcagtgagcgagcgagcgcgcagagagggagtggccaactccatcactaggggttcct 141 DNA PAT source 1..141 mol_type other DNA organism Synthetic construct misc_feature 1..141 note 3' ITR aggaacccctagtgatggagttggccactccctctctgcgcgctcgctcgctcactgaggccgggcgaccaaaggtcgcccgacgcccgggctttgcccgggcggcctcagtgagcgagcgagcgcgcagctgcagatctg 942 DNA PAT source 1..942 mol_type other DNA organism Synthetic construct misc_feature 1..942 note smCBA promoter ctagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggactatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgacgctgccttcgccccgtgccccgctccgccgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggcttgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagctagagcctctgctaaccatgttcatgccttcttctttttcctacagctcctgggcaacgtgctggttattgtgctgtctcatcattttggcaaag 221 AA PAT source 1..221 mol_type protein organism synthetic construct REGION 1..221 note K1-70 Heavy Chain EVQLVQSGAEVKKPGQSLKISCKASGYSLTDNWIGWVRQKPGKGLEWMGIIYPGDSDTRYSPSFQGQVTISADKSINTAYLQWSSLKASDTAIYYCVGLDWNYNPLRYWGPGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 214 AA PAT source 1..214 mol_type protein organism synthetic construct REGION 1..214 note K1-70 Light Chain QSVLTQPPSVSAAPGQKVTISCSGSSSDIGSNYVSWYQQFPGTAPKLLIYDNNKRPSAIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSRLGIAVFGGGTQLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLVSDFYPGAVTVAWKADGSPVKVGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCRVTHEGSTVEKTVAPTE 119 AA PAT source 1..119 mol_type protein organism synthetic construct REGION 1..119 note K1-70 VH EVQLVQSGAEVKKPGQSLKISCKASGYSLTDNWIGWVRQKPGKGLEWMGIIYPGDSDTRYSPSFQGQVTISADKSINTAYLQWSSLKASDTAIYYCVGLDWNYNPLRYWGPGTLVTVSS 110 AA PAT source 1..110 mol_type protein organism synthetic construct REGION 1..110 note K1-70 VL QSVLTQPPSVSAAPGQKVTISCSGSSSDIGSNYVSWYQQFPGTAPKLLIYDNNKRPSAIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSRLGIAVFGGGTQLTVL 8 AA PAT source 1..8 mol_type protein organism synthetic construct REGION 1..8 note K1-70 HCDR1 GYSLTDNW 8 AA PAT source 1..8 mol_type protein organism synthetic construct REGION 1..8 note K1-70 HCDR2 IYPGDSDT 12 AA PAT source 1..12 mol_type protein organism synthetic construct REGION 1..12 note K1-70 HCDR3 VGLDWNYNPLRY 8 AA PAT source 1..8 mol_type protein organism synthetic construct REGION 1..8 note K1-70 LCDR1 SSDIGSNY 11 AA PAT source 1..11 mol_type protein organism synthetic construct REGION 1..11 note K1-70 LCDR3 GTWDSRLGIAV 1671 DNA PAT source 1..1671 mol_type other DNA organism synthetic construct misc_feature 1..1671 note CAG promoter gacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggagtatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtcgaggtgagccccacgttctgcttcactctccccatctcccccccctccccacccccaattttgtatttatttattttttaattattttgtgcagcgatgggggcggggggggggggggggcgcgcgccaggcggggcggggcggggcgaggggcggggcggggcgaggcggagaggtgcggcggcagccaatcagagcggcgcgctccgaaagtttccttttatggcgaggcggcggcggcggcggccctataaaaagcgaagcgcgcggcgggcgggagtcgctgcgttgccttcgccccgtgccccgctccgcgccgcctcgcgccgcccgccccggctctgactgaccgcgttactcccacaggtgagcgggcgggacggcccttctcctccgggctgtaattagcgcttggtttaatgacggcttgtttcttttctgtggctgcgtgaaagccttgaggggctccgggagggccctttgtgcggggggagcggctcggggggtgcgtgcgtgtgtgtgtgcgtggggagcgccgcgtgcggctccgcgctgcccggcggctgtgagcgctgcgggcgcggcgcggggctttgtgcgctccgcagtgtgcgcgaggggagcgcggccgggggcggtgccccgcggtgcggggggctgcgaggggaacaaaggctgcgtgcggggtgtgtgcgtgggggggtgagcagggggtgtgggcgcgtcggtcgggctgcaaccccccctgcacccccctccccgagttgctgagcacggcccggcttcgggtgcggggctccgtacggggcgtggcgcggggctcgccgtgccgggcggggggtggcggcaggtgggggtgccgggcggggcggggccgcctcgggccggggagggctcgggggaggggcgcggcggcccccggagcgccggcggctgtcgaggcgcggcgagccgcagccattgccttttatggtaatcgtgcgagagggcgcagggacttcctttgtcccaaatctgtgcggagccgaaatctgggaggcgccgccgcaccccctctagcgggcgcggggcgaagcggtgcggcgccggcaggaaggaaatgggcggggagggccttcgtgcgtcgccgcgccgccgtccccttctccctctccagcctcggggctgtccgcggggggacggctgccttcgggggggacggggcagggcggggttcggcttctggcgtgtgaccggcggctctagagcctctgctaaccatgttcatgccttcttctttttcctacag