JBI6831WOPCT1 US 63/518.049 2023-08-07 JANSSEN BIOTECH, INC. JANSSEN BIOTECH, INC. STABILIZED CD3 ANTIGEN BINDING AGENTS AND METHODS OF USE THEREOF AGENTES DE UNIÓN AL ANTÍGENO CD3 ESTABILIZADOS Y MÉTODOS DE USO DE ESTOS 157 207 AA PAT source 1..207 mol_type protein organism Homo sapiens Homo sapiens MQSGTHWRVLGLCLLSVGVWGQDGNEEMGGITQTPYKVSISGTTVILTCPQYPGSEILWQHNDKNIGGDEDDKNIGSDEDHLSLKEFSELEQSGYYVCYPRGSKPEDANFYLYLRARVCENCMEMDVMSVATIVIVDICITGGLLLLVYYWSKNRKAKAKPVTRGAGAGGRQRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRRI 18 AA PAT source 1..18 mol_type protein organism synthetic construct constructo sintético GGGSGGSGGCPPCGGSGG 16 AA PAT source 1..16 mol_type protein organism synthetic construct constructo sintético GGGSGGCPPCGGGSGG 16 AA PAT source 1..16 mol_type protein organism synthetic construct constructo sintético GGSGGSGGCPPCGSGG 17 AA PAT source 1..17 mol_type protein organism synthetic construct constructo sintético GGGSGGSGGCPPCGSGG 17 AA PAT source 1..17 mol_type protein organism synthetic construct constructo sintético GGGSGGGSGCPPCGGGG 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético RSTMH 17 AA PAT source 1..17 mol_type protein organism synthetic construct constructo sintético YINPSSAYTNYNQKFQG 12 AA PAT source 1..12 mol_type protein organism synthetic construct constructo sintético PQVHYDYAGFPY 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético SASSSVSYMN 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético DSSKLAS 9 AA PAT source 1..9 mol_type protein organism synthetic construct constructo sintético QQWSRNPPT 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético GYTFTRS 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético NPSSAY 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético GYTFTRSTMH 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético YINPSSAYTN 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético TRSTMH 13 AA PAT source 1..13 mol_type protein organism synthetic construct constructo sintético WIGYINPSSAYTN 13 AA PAT source 1..13 mol_type protein organism synthetic construct constructo sintético ASPQVHYDYAGFP 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético SYMNWY 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético RWIYDSSKLA 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético QQWSRNPP 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético GYTFTRST 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético INPSSAYT 14 AA PAT source 1..14 mol_type protein organism synthetic construct constructo sintético ASPQVHYDYAGFPY 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético SSVSY 000 121 AA PAT source 1..121 mol_type protein organism synthetic construct constructo sintético QVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSS 106 AA PAT source 1..106 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIK 245 AA PAT source 1..245 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSS 4 AA PAT source 1..4 mol_type protein organism synthetic construct constructo sintético CPPC 107 AA PAT source 1..107 mol_type protein organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGQGTKVEIK 108 AA PAT source 1..108 mol_type protein organism synthetic construct constructo sintético EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQDYGFPWTFGQGTKVEIK 110 AA PAT source 1..110 mol_type protein organism synthetic construct constructo sintético NFMLTQPHSVSESPGKTVTISCTRSSGSLANYYVQWYQQRPGSSPTIVIFANNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQTYDPYSVVFGGGTKLTVL 110 AA PAT source 1..110 mol_type protein organism synthetic construct constructo sintético NFMLTQPHSVSESPGKTVTISCTRSSGSLANYYVQWYQQRPGQSPTIVIFANNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQTYDPYSVVFGGGTKLTVL 119 AA PAT source 1..119 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKYDGIYGELDFWGQGTLVTVSS 118 AA PAT source 1..118 mol_type protein organism synthetic construct constructo sintético EVQLVQSGAEVKKPGESLKISCKGSGYSFTSYWISWVRQMPGKGLEWMGIIDPSDSDTRYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCARGDGSTDLDYWGQGTLVTVSS 118 AA PAT source 1..118 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFGFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDLIHGVTRNWGQGTLVTVSS 20 AA PAT source 1..20 mol_type protein organism synthetic construct constructo sintético GGGGSGGGGSGGGGSGGGGS 254 AA PAT source 1..254 mol_type protein organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGQGTKVEIKRGGGGSGGGGSGGGGSGGGGSEVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKYDGIYGELDFWGQGTLVTVSSGHHHHHH 252 AA PAT source 1..252 mol_type protein organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGCAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGQGTKVEIKRGGGSGGSGGCPPCGGSGGEVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKYDGIYGELDFWGCGTLVTVSSGHHHHHH 255 AA PAT source 1..255 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKYDGIYGELDFWGQGTLVTVSSAGGGGSGGGGSGGGGSGGGGSDIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGQGTKVEIKRGHHHHHH 252 AA PAT source 1..252 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGCGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKYDGIYGELDFWGQGTLVTVSSGGGSGGSGGCPPCGGSGGDIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGCGTKVEIKRGHHHHHH 253 AA PAT source 1..253 mol_type protein organism synthetic construct constructo sintético EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQDYGFPWTFGQGTKVEIKGGGGSGGGGSGGGGSGGGGSEVQLVQSGAEVKKPGESLKISCKGSGYSFTSYWISWVRQMPGKGLEWMGIIDPSDSDTRYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCARGDGSTDLDYWGQGTLVTVSSGHHHHHH 251 AA PAT source 1..251 mol_type protein organism synthetic construct constructo sintético EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGCAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQDYGFPWTFGQGTKVEIKGGGSGGSGGCPPCGGSGGEVQLVQSGAEVKKPGESLKISCKGSGYSFTSYWISWVRQMPGKGLEWMGIIDPSDSDTRYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCARGDGSTDLDYWGCGTLVTVSSGHHHHHH 253 AA PAT source 1..253 mol_type protein organism synthetic construct constructo sintético EVQLVQSGAEVKKPGESLKISCKGSGYSFTSYWISWVRQMPGKGLEWMGIIDPSDSDTRYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCARGDGSTDLDYWGQGTLVTVSSGGGGSGGGGSGGGGSGGGGSEIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQDYGFPWTFGQGTKVEIKGHHHHHH 249 AA PAT source 1..249 mol_type protein organism synthetic construct constructo sintético EVQLVQSGAEVKKPGESLKISCKGSGYSFTSYWISWVRQMPGCGLEWMGIIDPSDSDTRYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCARGDGSTDLDYWGQGTLVTVSSGGGSGGCPPCGGGSGGEIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQDYGFPWTFGCGTKVEIKGHHHHHH 255 AA PAT source 1..255 mol_type protein organism synthetic construct constructo sintético NFMLTQPHSVSESPGKTVTISCTRSSGSLANYYVQWYQQRPGSSPTIVIFANNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQTYDPYSVVFGGGTKLTVLGGGGSGGGGSGGGGSGGGGSEVQLLESGGGLVQPGGSLRLSCAASGFGFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDLIHGVTRNWGQGTLVTVSSGHHHHHH 251 AA PAT source 1..251 mol_type protein organism synthetic construct constructo sintético NFMLTQPHSVSESPGKTVTISCTRSSGSLANYYVQWYQQRPGCSPTIVIFANNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQTYDPYSVVFGGGTKLTVLGGSGGSGGCPPCGSGGEVQLLESGGGLVQPGGSLRLSCAASGFGFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDLIHGVTRNWGCGTLVTVSSGHHHHHH 255 AA PAT source 1..255 mol_type protein organism synthetic construct constructo sintético NFMLTQPHSVSESPGKTVTISCTRSSGSLANYYVQWYQQRPGQSPTIVIFANNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQTYDPYSVVFGGGTKLTVLGGGGSGGGGSGGGGSGGGGSEVQLLESGGGLVQPGGSLRLSCAASGFGFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDLIHGVTRNWGQGTLVTVSSGHHHHHH 252 AA PAT source 1..252 mol_type protein organism synthetic construct constructo sintético NFMLTQPHSVSESPGKTVTISCTRSSGSLANYYVQWYQQRPGCSPTIVIFANNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQTYDPYSVVFGGGTKLTVLGGGSGGSGGCPPCGSGGEVQLLESGGGLVQPGGSLRLSCAASGFGFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDLIHGVTRNWGCGTLVTVSSGHHHHHH 255 AA PAT source 1..255 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFGFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDLIHGVTRNWGQGTLVTVSSGGGGSGGGGSGGGGSGGGGSNFMLTQPHSVSESPGKTVTISCTRSSGSLANYYVQWYQQRPGSSPTIVIFANNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQTYDPYSVVFGGGTKLTVLGHHHHHH 252 AA PAT source 1..252 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFGFSSYAMSWVRQAPGCGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDLIHGVTRNWGQGTLVTVSSGGGSGGGSGCPPCGGGGNFMLTQPHSVSESPGKTVTISCTRSSGSLANYYVQWYQQRPGQSPTIVIFANNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQTYDPYSVVFGCGTKLTVLGHHHHHH 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético SYAMS 17 AA PAT source 1..17 mol_type protein organism synthetic construct constructo sintético AISGGIGSTYYADSVKG 12 AA PAT source 1..12 mol_type protein organism synthetic construct constructo sintético DAVGATPYYFDY 13 AA PAT source 1..13 mol_type protein organism synthetic construct constructo sintético SGSSSNIGINYVS 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético DNNKRPS 11 AA PAT source 1..11 mol_type protein organism synthetic construct constructo sintético GTWDSSLSAVV 121 AA PAT source 1..121 mol_type protein organism synthetic construct constructo sintético EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGGIGSTYYADSVKGRFTISRDNSKNTLWLQMNSLRAEDTAVYYCAKDAVGATPYYFDYWGQGTLVTVSS 110 AA PAT source 1..110 mol_type protein organism synthetic construct constructo sintético QSVLTQPPSVSAAPGQKVTISCSGSSSNIGINYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAVVFGGGTKLTVL 451 AA PAT source 1..451 mol_type protein organism synthetic construct constructo sintético EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGGIGSTYYADSVKGRFTISRDNSKNTLWLQMNSLRAEDTAVYYCAKDAVGATPYYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 216 AA PAT source 1..216 mol_type protein organism synthetic construct constructo sintético QSVLTQPPSVSAAPGQKVTISCSGSSSNIGINYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 1353 DNA PAT source 1..1353 mol_type other DNA organism synthetic construct constructo sintético gaggtgcagctggttgaatctggcggaggattggttcagcctggcggttctctgagactgtcttgtgccgcttccggcttcaccttctccagctacgctatgtcctgggtccgacaggctcctggcaaaggactggaatgggtgtccgctatctctggcggcatcggctctacctactacgccgactctgtgaagggcagattcaccatcagccgggacaactccaagaacaccctgtggctgcagatgaactccctgagagccgaggataccgccgtgtactactgtgccaaggatgccgtgggcgctaccccttactacttcgattattggggccagggcaccctggtcaccgtttcttctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacccagacctacatctgcaacgtgaatcacaagcccagcaacaccaaggtggacaagaaagttgagcccaaatcttgtgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctcatgatctcccggacccctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtcgaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtcctgcgccgtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctcgtgagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccggttcacgcagaagtctctctccctgtctccgggaaaa 648 DNA PAT source 1..648 mol_type other DNA organism synthetic construct constructo sintético cagtctgtgctgacccagcctccttctgtgtctgctgctcctggccagaaagtgaccatctcctgctccggctcctcctccaacatcggcatcaactacgtgtcctggtatcagcagctgcccggcacagctcccaaactgctgatctacgacaacaacaagcggcccagcggcatccctgacagattctccggatctaagtccggcacctctgctaccctgggcatcacaggattgcagacaggcgacgaggccgactactattgcggcacctgggactcttctctgtccgccgttgtttttggcggtggcaccaagctgacagtgctgggtcagcccaaggctgcacccagtgtcactctgttcccgccctcctctgaggagcttcaagccaacaaggccacactggtgtgtctcataagtgacttctacccgggagccgtgacagtggcctggaaggccgatagcagccccgtcaaggcgggagtcgaaaccaccacaccctccaaacaaagcaacaacaagtacgcggccagcagctatctgagcctgacgcctgagcagtggaagtcccacagaagctacagctgccaggtcacgcatgaagggagcaccgtggagaagacagtggcccctacagaatgttca 477 AA PAT source 1..477 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLWCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 1431 DNA PAT source 1..1431 mol_type other DNA organism synthetic construct constructo sintético gagatcgtgctgacccagtctcctgccacactgagtgcttctccaggcgagagagtgaccctgtcctgctccgcttcctcctccgtgtcctacatgaactggtatcagcagaagcccggctgcgcccctagaagatggatctacgactcctccaagctggcctctggcgtgcctgctagattttccggctctggctctggcagagactataccctgacaatctccagcctggaacctgaggacttcgccgtgtactactgccagcagtggtctaggaaccctcctacctttggcggaggcaccaaggtggaaatcaagggcggaggttctggtggatctggcggatgtcctccttgtggtggaagcggcggacaggttcagctggttcagtctggcgccgaagtgaagaaacctggctcctccgtgaaagtgtcctgcaaggcttccggctacacctttaccagatccaccatgcactgggtcaagcaggcccctggacaaggcttggagtggatcggctacatcaaccccagctccgcctacaccaactacaaccagaaattccagggcagagtgaccctgaccgccgacaagtctacctccaccgcctacatggaactgtccagcctgagatctgaggacaccgccgtgtactactgcgcctctcctcaggttcactacgactacgccggctttccttattggggctgtggcaccctggtcaccgtttcttctgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctcatgatctcccggacccctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtcgaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagtctctctccctgtctccgggaaaa 363 DNA PAT source 1..363 mol_type other DNA organism synthetic construct constructo sintético caggttcagctggttcagtctggcgccgaagtgaagaaacctggctcctccgtgaaagtgtcctgcaaggcttccggctacacctttaccagatccaccatgcactgggtcaagcaggcccctggacaaggcttggagtggatcggctacatcaaccccagctccgcctacaccaactacaaccagaaattccagggcagagtgaccctgaccgccgacaagtctacctccaccgcctacatggaactgtccagcctgagatctgaggacaccgccgtgtactactgcgcctctcctcaggttcactacgactacgccggctttccttattggggctgtggcaccctggtcaccgtttcttct 318 DNA PAT source 1..318 mol_type other DNA organism synthetic construct constructo sintético gagatcgtgctgacccagtctcctgccacactgagtgcttctccaggcgagagagtgaccctgtcctgctccgcttcctcctccgtgtcctacatgaactggtatcagcagaagcccggctgcgcccctagaagatggatctacgactcctccaagctggcctctggcgtgcctgctagattttccggctctggctctggcagagactataccctgacaatctccagcctggaacctgaggacttcgccgtgtactactgccagcagtggtctaggaaccctcctacctttggcggaggcaccaaggtggaaatcaag 1431 DNA PAT source 1..1431 mol_type other DNA organism synthetic construct constructo sintético gagatcgtgctgacccagtctcctgccacactgagtgcttctccaggcgagagagtgaccctgtcctgctccgcttcctcctccgtgtcctacatgaactggtatcagcagaagcccggctgcgcccctagaagatggatctacgactcctccaagctggcctctggcgtgcctgctagattttccggctctggctctggcagagactataccctgacaatctccagcctggaacctgaggacttcgccgtgtactactgccagcagtggtctaggaaccctcctacctttggcggaggcaccaaggtggaaatcaagggcggaggttctggtggatctggcggatgtcctccttgtggtggaagcggcggacaggttcagctggttcagtctggcgccgaagtgaagaaacctggctcctccgtgaaagtgtcctgcaaggcttccggctacacctttaccagatccaccatgcactgggtcaagcaggcccctggacaaggcttggagtggatcggctacatcaaccccagctccgcctacaccaactacaaccagaaattccagggcagagtgaccctgaccgccgacaagtctacctccaccgcctacatggaactgtccagcctgagatctgaggacaccgccgtgtactactgcgcctctcctcaggttcactacgactacgccggctttccttattggggctgtggcaccctggtcaccgtttcttctgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctcatgatctcccggacccctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtcgaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagtctctctccctgtctccgggaaaa 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético DYSMN 17 AA PAT source 1..17 mol_type protein organism synthetic construct constructo sintético SISSISSYVKYADSVKG 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético GHYFDY 11 AA PAT source 1..11 mol_type protein organism synthetic construct constructo sintético RASQSVSSNLA 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético GASTRAT 9 AA PAT source 1..9 mol_type protein organism synthetic construct constructo sintético QQYNNWPRT 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético GFTFSDY 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético SSISSY 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético GFTFSDYSMN 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético SISSISSYVK 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético SDYSMN 13 AA PAT source 1..13 mol_type protein organism synthetic construct constructo sintético WVSSISSISSYVK 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético ARGHYFD 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético SSNLAWY 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético LLIYGASTRA 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético QQYNNWPR 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético GFTFSDYS 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético ISSISSYV 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético ARGHYFDY 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético QSVSSN 000 115 AA PAT source 1..115 mol_type protein organism synthetic construct constructo sintético EVQLVESGGGRVKPGGSLRLSCAASGFTFSDYSMNWVRQAPGKGLEWVSSISSISSYVKYADSVKGRFTMSRDNAKNSLFLQMNSLRDEDMAVYYCARGHYFDYWGQGTLVTVSS 345 DNA PAT source 1..345 mol_type other DNA organism synthetic construct constructo sintético gaggtgcagctggttgaatctggcggcggaagagtgaagcctggcggatctctgagactgtcttgtgccgcctctggcttcaccttctccgactactccatgaactgggtccgacaggctcctggcaaaggcctggaatgggtgtcctctatctcctccatctccagctacgtgaagtacgccgactccgtgaagggcagattcaccatgtccagagacaacgccaagaactccctgttcctgcagatgaacagcctgcgcgacgaggacatggccgtgtactattgtgccagaggccactacttcgactactggggacagggcacactggtcacagtctcttct 107 AA PAT source 1..107 mol_type protein organism synthetic construct constructo sintético EIVMTQSPATLSVSPGERATLSCRASQSVSSNLAWYQQKPGLAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWPRTFGQGTKVEIK 321 DNA PAT source 1..321 mol_type other DNA organism synthetic construct constructo sintético gagatcgtgatgacccagtctcctgccacactgtctgtgtctcccggcgagagagctaccctgtcttgtagagcctctcagtccgtgtcctccaacctggcctggtatcagcagaagcctggactggctccccggctgttgatctatggcgcttctaccagagccacaggcatccccgctagattctccggctctggctctggcacagagtttaccctgaccatctccagcctgcagtccgaggatttcgccgtgtactactgccagcagtacaacaactggccccggacctttggccagggcaccaaggtggaaatcaag 477 AA PAT source 1..477 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLWCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 445 AA PAT source 1..445 mol_type protein organism synthetic construct constructo sintético EVQLVESGGGRVKPGGSLRLSCAASGFTFSDYSMNWVRQAPGKGLEWVSSISSISSYVKYADSVKGRFTMSRDNAKNSLFLQMNSLRDEDMAVYYCARGHYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 214 AA PAT source 1..214 mol_type protein organism synthetic construct constructo sintético EIVMTQSPATLSVSPGERATLSCRASQSVSSNLAWYQQKPGLAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 1431 DNA PAT source 1..1431 mol_type other DNA organism synthetic construct constructo sintético gagatcgtgctgacccagtctcctgccacactgagtgcttctccaggcgagagagtgaccctgtcctgctccgcttcctcctccgtgtcctacatgaactggtatcagcagaagcccggctgcgcccctagaagatggatctacgactcctccaagctggcctctggcgtgcctgctagattttccggctctggctctggcagagactataccctgacaatctccagcctggaacctgaggacttcgccgtgtactactgccagcagtggtctaggaaccctcctacctttggcggaggcaccaaggtggaaatcaagggcggaggttctggtggatctggcggatgtcctccttgtggtggaagcggcggacaggttcagctggttcagtctggcgccgaagtgaagaaacctggctcctccgtgaaagtgtcctgcaaggcttccggctacacctttaccagatccaccatgcactgggtcaagcaggcccctggacaaggcttggagtggatcggctacatcaaccccagctccgcctacaccaactacaaccagaaattccagggcagagtgaccctgaccgccgacaagtctacctccaccgcctacatggaactgtccagcctgagatctgaggacaccgccgtgtactactgcgcctctcctcaggttcactacgactacgccggctttccttattggggctgtggcaccctggtcaccgtttcttctgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctcatgatctcccggacccctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtcgaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagtctctctccctgtctccgggaaaa 1335 DNA PAT source 1..1335 mol_type other DNA organism synthetic construct constructo sintético gaggtgcagctggttgaatctggcggcggaagagtgaagcctggcggatctctgagactgtcttgtgccgcctctggcttcaccttctccgactactccatgaactgggtccgacaggctcctggcaaaggcctggaatgggtgtcctctatctcctccatctccagctacgtgaagtacgccgactccgtgaagggcagattcaccatgtccagagacaacgccaagaactccctgttcctgcagatgaacagcctgcgcgacgaggacatggccgtgtactattgtgccagaggccactacttcgactactggggacagggcacactggtcacagtctcttctgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacccagacctacatctgcaacgtgaatcacaagcccagcaacaccaaggtggacaagaaagttgagcccaaatcttgtgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctcatgatctcccggacccctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtcgaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtcctgcgccgtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctcgtgagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccggttcacgcagaagtctctctccctgtctccgggaaaa 642 DNA PAT source 1..642 mol_type other DNA organism synthetic construct constructo sintético gagatcgtgatgacccagtctcctgccacactgtctgtgtctcccggcgagagagctaccctgtcttgtagagcctctcagtccgtgtcctccaacctggcctggtatcagcagaagcctggactggctccccggctgttgatctatggcgcttctaccagagccacaggcatccccgctagattctccggctctggctctggcacagagtttaccctgaccatctccagcctgcagtccgaggatttcgccgtgtactactgccagcagtacaacaactggccccggacctttggccagggcaccaaggtggaaatcaagcgtactgtggctgcaccatctgtcttcatcttcccgccatctgatgagcagttgaaatctggaactgcctctgttgtgtgcctgctgaataacttctatcccagagaggccaaagtacagtggaaggtggataacgccctccaatcgggtaactcccaggagagtgtcacagagcaggacagcaaggacagcacctacagcctcagcagcaccctgacgctgagcaaagcagactacgagaaacacaaagtctacgcctgcgaagtcacccatcagggcctgagctcgcccgtcacaaagagcttcaacaggggagagtgt 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético HYYWS 16 AA PAT source 1..16 mol_type protein organism synthetic construct constructo sintético RIYTSGSTNYNPSLKS 9 AA PAT source 1..9 mol_type protein organism synthetic construct constructo sintético DRYTGYFDL 12 AA PAT source 1..12 mol_type protein organism synthetic construct constructo sintético RASQSVSSSYLA 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético GASSRAT 9 AA PAT source 1..9 mol_type protein organism synthetic construct constructo sintético QQYGSSPPT 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético GASISHY 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético YTSGS 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético GASISHYYWS 9 AA PAT source 1..9 mol_type protein organism synthetic construct constructo sintético RIYTSGSTN 6 AA PAT source 1..6 mol_type protein organism synthetic construct constructo sintético SHYYWS 12 AA PAT source 1..12 mol_type protein organism synthetic construct constructo sintético WIGRIYTSGSTN 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético ARDRYTGYFD 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético SSSYLAWY 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético LLIYGASSRA 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético QQYGSSPP 8 AA PAT source 1..8 mol_type protein organism synthetic construct constructo sintético GASISHYY 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético IYTSGST 11 AA PAT source 1..11 mol_type protein organism synthetic construct constructo sintético ARDRYTGYFDL 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético QSVSSSY 117 AA PAT source 1..117 mol_type protein organism synthetic construct constructo sintético QVQLQESGPGLVKPSETLSLTCTVSGASISHYYWSWIRRPAGKGLEWIGRIYTSGSTNYNPSLKSRVTVSVDTSKNQFSLKLSSVTAADTAVYYCARDRYTGYFDLWGRGTLVTVSS 108 AA PAT source 1..108 mol_type protein organism synthetic construct constructo sintético EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPPTFGGGTKLEIK 351 DNA PAT source 1..351 mol_type other DNA organism synthetic construct constructo sintético caggtgcagctgcaggagtcgggcccaggactggtgaagccttcggagaccctgtccctcacctgcactgtctctggtgcctccatcagtcattactactggagctggatccggcggcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccgtgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtatattactgtgcgagagatcgatatacggggtacttcgatctctggggccgtggcaccctggtcactgtctcctca 324 DNA PAT source 1..324 mol_type other DNA organism synthetic construct constructo sintético gaaattgtgttgacgcagtctccaggcaccctgtctttgtctccaggggaaagagccaccctctcctgcagggccagtcagagtgttagcagcagctacttagcctggtaccagcagaaacctggccaggctcccaggctcctcatctatggtgcatccagcagggccactggcatcccagacaggttcagtggcagtgggtctgggacagacttcactctcaccatcagcagactggagcctgaagattttgcagtttattactgtcagcagtatggtagctcacctcccactttcggcggagggaccaagctggagatcaaa 5 AA PAT source 1..5 mol_type protein organism synthetic construct constructo sintético RSTMH 17 AA PAT source 1..17 mol_type protein organism synthetic construct constructo sintético YINPSSAYTNYNQKFQG 12 AA PAT source 1..12 mol_type protein organism synthetic construct constructo sintético PQVHYDYAGFPY 10 AA PAT source 1..10 mol_type protein organism synthetic construct constructo sintético SASSSVSYMN 7 AA PAT source 1..7 mol_type protein organism synthetic construct constructo sintético DSSKLAS 9 AA PAT source 1..9 mol_type protein organism synthetic construct constructo sintético QQWSRNPPT 121 AA PAT source 1..121 mol_type protein organism synthetic construct constructo sintético QVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSS 106 AA PAT source 1..106 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIK 245 AA PAT source 1..245 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSS 363 DNA PAT source 1..363 mol_type other DNA organism synthetic construct constructo sintético caagtacaacttgttcaatctggcgctgaagtcaaaaaacccggatctagtgttaaagtttcatgtaaggcatcaggctatactttcactcggtctacaatgcactgggtcaagcaggctccagggcaaggtttggaatggatagggtacataaatccttctagcgcctatactaattacaaccagaagtttcagggacgtgttactctgactgctgacaaatcaacatctacagcctatatggaactgtcttcattgaggagtgaggacactgctgtgtattactgcgcttctcctcaggtgcactatgattacgctggctttccctactggggttgtggcaccctcgtcaccgtttcatct 318 DNA PAT source 1..318 mol_type other DNA organism synthetic construct constructo sintético gagatcgtcttgactcagtcccctgcaaccctcagcgcaagtcccggagagcgcgttacattgagttgttccgcatccagttcagtcagctacatgaactggtaccaacaaaagcccggttgtgctccaagaaggtggatctatgattccagtaagctggcctccggggtcccagcaaggttcagcggttccggcagcggaagggactacactctgaccataagttcccttgaaccagaagacttcgccgtctattattgtcagcagtggtcccgaaatccacctaccttcgggggcggcactaaagtggagattaaa 735 DNA PAT source 1..735 mol_type other DNA organism synthetic construct constructo sintético gagatcgtcttgactcagtcccctgcaaccctcagcgcaagtcccggagagcgcgttacattgagttgttccgcatccagttcagtcagctacatgaactggtaccaacaaaagcccggttgtgctccaagaaggtggatctatgattccagtaagctggcctccggggtcccagcaaggttcagcggttccggcagcggaagggactacactctgaccataagttcccttgaaccagaagacttcgccgtctattattgtcagcagtggtcccgaaatccacctaccttcgggggcggcactaaagtggagattaaaggaggaggtagtggcggctccggtggatgtcctccttgcggaggatcaggaggtcaagtacaacttgttcaatctggcgctgaagtcaaaaaacccggatctagtgttaaagtttcatgtaaggcatcaggctatactttcactcggtctacaatgcactgggtcaagcaggctccagggcaaggtttggaatggatagggtacataaatccttctagcgcctatactaattacaaccagaagtttcagggacgtgttactctgactgctgacaaatcaacatctacagcctatatggaactgtcttcattgaggagtgaggacactgctgtgtattactgcgcttctcctcaggtgcactatgattacgctggctttccctactggggttgtggcaccctcgtcaccgtttcatct 447 AA PAT source 1..447 mol_type protein organism synthetic construct constructo sintético QVQLQESGPGLVKPSETLSLTCTVSGASISHYYWSWIRRPAGKGLEWIGRIYTSGSTNYNPSLKSRVTVSVDTSKNQFSLKLSSVTAADTAVYYCARDRYTGYFDLWGRGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 215 AA PAT source 1..215 mol_type protein organism synthetic construct constructo sintético EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 477 AA PAT source 1..477 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLWCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 1341 DNA PAT source 1..1341 mol_type other DNA organism synthetic construct constructo sintético caggtgcagctgcaggagtcgggcccaggactggtgaagccttcggagaccctgtccctcacctgcactgtctctggtgcctccatcagtcattactactggagctggatccggcggcccgccgggaagggactggagtggattgggcgtatctataccagtgggagcaccaactacaacccctccctcaagagtcgagtcaccgtgtcagtagacacgtccaagaaccagttctccctgaagctgagctctgtgaccgccgcggacacggccgtatattactgtgcgagagatcgatatacggggtacttcgatctctggggccgtggcaccctggtcactgtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacccagacctacatctgcaacgtgaatcacaagcccagcaacaccaaggtggacaagaaagttgagcccaaatcttgtgacaaaactcacacatgtccaccgtgcccagcacctgaagcagcagggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctcatgatctcccggacccctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtctccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtcctgcgcggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctcgtcagcaagctcaccgtggacaagtctagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccggttcacgcagaagagcctctccctgtctccgggtaaa 645 DNA PAT source 1..645 mol_type other DNA organism synthetic construct constructo sintético gaaattgtgttgacgcagtctccaggcaccctgtctttgtctccaggggaaagagccaccctctcctgcagggccagtcagagtgttagcagcagctacttagcctggtaccagcagaaacctggccaggctcccaggctcctcatctatggtgcatccagcagggccactggcatcccagacaggttcagtggcagtgggtctgggacagacttcactctcaccatcagcagactggagcctgaagattttgcagtttattactgtcagcagtatggtagctcacctcccactttcggcggagggaccaagctggagatcaaacgtacggtggctgcaccatctgtcttcatcttcccgccatctgatgagcagttgaaatctggaactgcctctgttgtgtgcctgctgaataacttctatcccagagaggccaaagtacagtggaaggtggataacgccctccaatcgggtaactcccaggagagtgtcacagagcaggacagcaaggacagcacctacagcctcagcagcaccctgacgctgagcaaagcagactacgagaaacacaaagtctacgcctgcgaagtcacccatcagggcctgagctcgcccgtcacaaagagcttcaacaggggagagtgt 1431 DNA PAT source 1..1431 mol_type other DNA organism synthetic construct constructo sintético gagatcgtcttgactcagtcccctgcaaccctcagcgcaagtcccggagagcgcgttacattgagttgttccgcatccagttcagtcagctacatgaactggtaccaacaaaagcccggttgtgctccaagaaggtggatctatgattccagtaagctggcctccggggtcccagcaaggttcagcggttccggcagcggaagggactacactctgaccataagttcccttgaaccagaagacttcgccgtctattattgtcagcagtggtcccgaaatccacctaccttcgggggcggcactaaagtggagattaaaggaggaggtagtggcggctccggtggatgtcctccttgcggaggatcaggaggtcaagtacaacttgttcaatctggcgctgaagtcaaaaaacccggatctagtgttaaagtttcatgtaaggcatcaggctatactttcactcggtctacaatgcactgggtcaagcaggctccagggcaaggtttggaatggatagggtacataaatccttctagcgcctatactaattacaaccagaagtttcagggacgtgttactctgactgctgacaaatcaacatctacagcctatatggaactgtcttcattgaggagtgaggacactgctgtgtattactgcgcttctcctcaggtgcactatgattacgctggctttccctactggggttgtggcaccctcgtcaccgtttcatctgagcccaaatctagcgacaaaactcacacatgtccaccgtgcccagcacctgaagcagcagggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctcatgatctcccggacccctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtctccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagtctagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagagcctctccctgtctccgggtaaa 245 AA PAT source 1..245 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSS 245 AA PAT source 1..245 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSS 245 AA PAT source 1..245 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSS 245 AA PAT source 1..245 mol_type protein organism synthetic construct constructo sintético EIVLTQSPATLSASPGERVTLSCSASSSVSYMNWYQQKPGCAPRRWIYDSSKLASGVPARFSGSGSGRDYTLTISSLEPEDFAVYYCQQWSRNPPTFGGGTKVEIKGGGSGGSGGCPPCGGSGGQVQLVQSGAEVKKPGSSVKVSCKASGYTFTRSTMHWVKQAPGQGLEWIGYINPSSAYTNYNQKFQGRVTLTADKSTSTAYMELSSLRSEDTAVYYCASPQVHYDYAGFPYWGCGTLVTVSS 450 AA PAT source 1..450 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFIFSNYYMAWVRLAPGKGLEWVSSISIGGGKSSYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCVRHPQLGPNPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 218 AA PAT source 1..218 mol_type protein organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSVTISSVDLMNWYQQKPGKAPKLLIYRASNLASGIPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSRESPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 450 AA PAT source 1..450 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFIFSNYYMAWVRLAPGKGLEWVSSISIGGGKSHYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCVRHPSLGPNPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 218 AA PAT source 1..218 mol_type protein organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSVTISSVDLMNWYQQKPGKAPKLLIYRASNLASGIPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSRESPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 450 AA PAT source 1..450 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFIFSNYYMAWVRLAPGKGLEWVSSISIGGGKSHYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCVRHPQSGPNPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 218 AA PAT source 1..218 mol_type protein organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSVTISSVDLMNWYQQKPGKAPKLLIYRASNLASGIPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSRESPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 450 AA PAT source 1..450 mol_type protein organism synthetic construct constructo sintético EVQLLESGGGLVQPGGSLRLSCAASGFIFSNYYMAWVRLAPGKGLEWVSSISIGGGKSHYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCVRHPQLGPNPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLMISRTPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 218 AA PAT source 1..218 mol_type protein organism synthetic construct constructo sintético DIQMTQSPSSLSASVGDRVTITCRASQSVTISSVDLMNWYQQKPGKAPKLLIYRASNLASGIPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSRESPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 21 AA PAT source 1..21 mol_type protein organism synthetic construct constructo sintético AGGGGSGGGGSGGGGSGGGGS 4 AA PAT source 1..4 mol_type protein organism synthetic construct constructo sintético REGION 1 note When part of an spFv VL domain, an intrachain disulfide bond will be formed Cuando forma parte de un dominio spFv VL, se formará un enlace disulfuro intracadena REGION 4 note When part of an spFv VH domain, an intrachain disulfide bond will be formed Cuando forma parte de un dominio spFv VH, se formará un enlace disulfuro intracadena CPPC