EP JBI6837 US 63/608.030 2023-12-08 Janssen Biotech, Inc Janssen Biotech, Inc CD33 ANTIBODIES, CD33/Vδ2 MULTISPECIFIC ANTIBODIES AND USES THEREOF ANTICUERPOS DE CD33, ANTICUERPOS MULTIESPECÍFICOS DE CD33/Vδ2 Y USOS DE ESTOS 111 851 AA PAT source 1..851 mol_type protein note C33W1 C33W1 organism synthetic construct constructo sintético DPRVRLEVQESVTVQEGLCVLVPCTFFHPVPYHTRNSPVHGYWFREGAIVSLDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMEKGSTKYSYKSTQLSVHVTDLTHRPQILIPGALDPDHSKNLTCSVPWACEQGTPPIFSWMSAAPTSLGLRTTHSSVLIITPRPQDHGTNLTCQVKFPGAGVTTERTIQLNVSYASQNPRTDIFLGDGSGKQGVVQGSGSGSENLYFQGVRSSSDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQSPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLGGGSHHHHHH 855 AA PAT source 1..855 mol_type protein note C33W2 C33W2 organism synthetic construct constructo sintético DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGSGSGSENLYFQGVRSSSDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQSPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLGGGSHHHHHH 718 AA PAT source 1..718 mol_type protein note C33W3 C33W3 organism synthetic construct constructo sintético DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQSPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLHHHHHH 715 AA PAT source 1..715 mol_type protein note C33W4 C33W4 organism synthetic construct constructo sintético VHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQSPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLHHHHHH 135 AA PAT source 1..135 mol_type protein note C33W8 C33W8 organism synthetic construct constructo sintético DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRGSHHHHHH 132 AA PAT source 1..132 mol_type protein note C33W9 C33W9 organism synthetic construct constructo sintético VHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGSHHHHHH 251 AA PAT source 1..251 mol_type protein note C33W10 C33W10 organism synthetic construct constructo sintético QDLEFQLVAPESVTVEEGLCVHVPCSVFYPSIKLTLGPVTGSWLRKGVSLHEDSPVATSDPRQLVQKATQGRFQLLGDPQKHDCSLFIRDAQKNDTGMYFFRVVREPFVRYSYKKSQLSLHVTSLSRTPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGSHHHHHH 251 AA PAT source 1..251 mol_type protein note C33W12 C33W12 organism synthetic construct constructo sintético QDLEFQLVAPESVTVEEGLCVHVPCSVFYPSIKLTLGPVTGSWLRKGVSLHEDSPVATSDPRQLVQKATQGRFQLLGDPQKHDCSLFIRDAQKNDTGMYFFRVVREPFVRYSYKKSQLSLHVTSLSRTPQILIPGALDPDHSKNLTCSVPWACEQGTPPIFSWMSAAPTSLGLRTTHSSVLIITPRPQDHGTNLTCQVKFPGAGVTTERTIQLNVSYASQNPRTDIFLGDGSGRKARKQGVVQGSHHHHHH 250 AA PAT source 1..250 mol_type protein note C33W49 C33W49 organism synthetic construct constructo sintético DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGSHHHHHH 246 AA PAT source 1..246 mol_type protein note C33W50 C33W50 organism synthetic construct constructo sintético DPRVRLEVQESVTVQEGLCVLVPCTFFHPVPYHTRNSPVHGYWFREGAIVSLDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMEKGSTKYSYKSTQLSVHVTDLTHRPQILIPGALDPDHSKNLTCSVPWACEQGTPPIFSWMSAAPTSLGLRTTHSSVLIITPRPQDHGTNLTCQVKFPGAGVTTERTIQLNVSYASQNPRTDIFLGDGSGKQGVVQGSHHHHHH 230 AA PAT source 1..230 mol_type protein note C33W51 C33W51 organism synthetic construct constructo sintético DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGHHHHHH 10 AA PAT source 1..10 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis GFTFDDYTMH 10 AA PAT source 1..10 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis LVSWSGGSAY 10 AA PAT source 1..10 mol_type protein note CDR3 CDR3 organism Ablexis mouse Ratón ablexis ESAYNAYFDY 17 AA PAT source 1..17 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis KSSQSVLYSSNNKNYLA 7 AA PAT source 1..7 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis WASTRES 9 AA PAT source 1..9 mol_type protein note CDR3 CDR3 organism Ablexis mouse Ratón ablexis HQFYITPYT 5 AA PAT source 1..5 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis DYTMH 17 AA PAT source 1..17 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis LVSWSGGSAYYVDSVKG 7 AA PAT source 1..7 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis GFTFDDY 6 AA PAT source 1..6 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis SWSGGS 8 AA PAT source 1..8 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis GFTFDDYT 8 AA PAT source 1..8 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis VSWSGGSA 12 AA PAT source 1..12 mol_type protein note CDR3 CDR3 organism Ablexis mouse Ratón ablexis AKESAYNAYFDY 12 AA PAT source 1..12 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis QSVLYSSNNKNY 000 10 AA PAT source 1..10 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis GFTFSRYWMS 10 AA PAT source 1..10 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis NIKRDGSEKY 9 AA PAT source 1..9 mol_type protein note CDR3 CDR3 organism Ablexis mouse Ratón ablexis NSGTWEFDQ 13 AA PAT source 1..13 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis TRSSGSIASNDVQ 7 AA PAT source 1..7 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis EDKQRPS 9 AA PAT source 1..9 mol_type protein note CDR3 CDR3 organism Ablexis mouse Ratón ablexis QSYDNNNQV 5 AA PAT source 1..5 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis RYWMS 17 AA PAT source 1..17 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis NIKRDGSEKYYVDAVRG 7 AA PAT source 1..7 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis GFTFSRY 6 AA PAT source 1..6 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis KRDGSE 8 AA PAT source 1..8 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis GFTFSRYW 8 AA PAT source 1..8 mol_type protein note CDR2 CDR2 organism Ablexis mouse Ratón ablexis IKRDGSEK 11 AA PAT source 1..11 mol_type protein note CDR3 CDR3 organism Ablexis mouse Ratón ablexis ARNSGTWEFDQ 8 AA PAT source 1..8 mol_type protein note CDR1 CDR1 organism Ablexis mouse Ratón ablexis SGSIASND 000 119 AA PAT source 1..119 mol_type protein organism Ablexis mouse Ratón ablexis EVQLVESGGDVVQPGGSLRLSCAASGFTFDDYTMHWVRQAPGKGLEWVSLVSWSGGSAYYVDSVKGRFTISRDNSKNSLYLQMNSLKSEDTALYYCAKESAYNAYFDYWGQGTLVTVSS 113 AA PAT source 1..113 mol_type protein organism Ablexis mouse Ratón ablexis DIVMTQSPDSLAVSLGERATIYCKSSQSVLYSSNNKNYLAWYQQKAGQPPELLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVALYYCHQFYITPYTFGQGTKVEIK 118 AA PAT source 1..118 mol_type protein organism Ablexis mouse Ratón ablexis EVQLVESGGGLVQPGGSLRLSCAASGFTFSRYWMSWVRQAPGKGLEWMANIKRDGSEKYYVDAVRGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARNSGTWEFDQWGQGTLVTVSS 110 AA PAT source 1..110 mol_type protein organism Ablexis mouse Ratón ablexis NFMLTQPHSVSESPGKTVIISCTRSSGSIASNDVQWYQQRPGSSPTIVIYEDKQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQSYDNNNQVFGGGTKLTVL 10 AA PAT source 1..10 mol_type protein note CDR1 CDR1 organism Llama Llama GSIFSIFDMG 9 AA PAT source 1..9 mol_type protein note CDR2 CDR2 organism Llama Llama RITNGGITN 15 AA PAT source 1..15 mol_type protein note CDR3 CDR3 organism Llama Llama DIAANIGSNILYDDY 5 AA PAT source 1..5 mol_type protein note CDR1 CDR1 organism Llama Llama IFDMG 16 AA PAT source 1..16 mol_type protein note CDR2 CDR2 organism Llama Llama RITNGGITNYLDSVKG 7 AA PAT source 1..7 mol_type protein note CDR1 CDR1 organism Llama Llama GSIFSIF 5 AA PAT source 1..5 mol_type protein note CDR2 CDR2 organism Llama Llama TNGGI 8 AA PAT source 1..8 mol_type protein note CDR1 CDR1 organism Llama Llama GSIFSIFD 7 AA PAT source 1..7 mol_type protein note CDR2 CDR2 organism Llama Llama ITNGGIT 10 AA PAT source 1..10 mol_type protein note CDR1 CDR1 organism Llama Llama GSIFSINAMG 9 AA PAT source 1..9 mol_type protein note CDR2 CDR2 organism Llama Llama RITGGGATD 15 AA PAT source 1..15 mol_type protein note CDR3 CDR3 organism Llama Llama DLVTRVGSDLLYDDY 5 AA PAT source 1..5 mol_type protein note CDR1 CDR1 organism Llama Llama INAMG 16 AA PAT source 1..16 mol_type protein note CDR2 CDR2 organism Llama Llama RITGGGATDYVDSVKG 7 AA PAT source 1..7 mol_type protein note CDR1 CDR1 organism Llama Llama GSIFSIN 5 AA PAT source 1..5 mol_type protein note CDR2 CDR2 organism Llama Llama TGGGA 8 AA PAT source 1..8 mol_type protein note CDR1 CDR1 organism Llama Llama GSIFSINA 7 AA PAT source 1..7 mol_type protein note CDR2 CDR2 organism Llama Llama ITGGGAT 17 AA PAT source 1..17 mol_type protein note CDR3 CDR3 organism Llama Llama YADLVTRVGSDLLYDDY 123 AA PAT source 1..123 mol_type protein organism Llama Llama QVQLVESGGGLVQAGGSLRLSCEASGSIFSIFDMGWYRRPPGAQRELVARITNGGITNYLDSVKGRFSISRDNAKNTVYLQMNSLNAEDTAVYYCYADIAANIGSNILYDDYWGQGTQVTVSS 123 AA PAT source 1..123 mol_type protein organism Llama Llama EVQVVESGGGLVQGGGSLRLSCAASGSIFSINAMGWYHQAPGKQRELVARITGGGATDYVDSVKGRFTISLDSAKSTVYLQMNSLKPEDTAVYHCYADLVTRVGSDLLYDDYWGQGTQVTVSS 358 AA PAT source 1..358 mol_type protein note Heavy chain 1 LAVA177 LAVA177 de cadena pesada 1 organism synthetic construct constructo sintético EVQLVESGGGLVQAGGSLRLSCAASGRPFSNYGMGWFRQAPGKKREFVAGISWSGGSTDYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAAVFSGAETAYYPSDDYDYWGQGTQVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLYITREPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLWCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 355 AA PAT source 1..355 mol_type protein note Heavy Chain 2 JL45 JL45 de cadena pesada 2 organism synthetic construct constructo sintético QVQLVESGGGLVQAGGSLRLSCEASGSIFSIFDMGWYRRPPGAQRELVARITNGGITNYLDSVKGRFSISRDNAKNTVYLQMNSLNAEDTAVYYCYADIAANIGSNILYDDYWGQGTQVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLYITREPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 000 449 AA PAT source 1..449 mol_type protein note Heavy chain 2 C33SB1SC1494 cadena pesada 2 C33SB1SC1494 organism synthetic construct constructo sintético EVQLVESGGDVVQPGGSLRLSCAASGFTFDDYTMHWVRQAPGKGLEWVSLVSWSGGSAYYVDSVKGRFTISRDNSKNSLYLQMNSLKSEDTALYYCAKESAYNAYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLYITREPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 220 AA PAT source 1..220 mol_type protein note Light chain 2 C33SB1SC1494 cadena ligera 2 C33SB1SC1494 organism synthetic construct constructo sintético DIVMTQSPDSLAVSLGERATIYCKSSQSVLYSSNNKNYLAWYQQKAGQPPELLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVALYYCHQFYITPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 448 AA PAT source 1..448 mol_type protein note Heavy chain 2 C33F1318 cadena pesada 2 C33F1318 organism synthetic construct constructo sintético EVQLVESGGGLVQPGGSLRLSCAASGFTFSRYWMSWVRQAPGKGLEWMANIKRDGSEKYYVDAVRGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARNSGTWEFDQWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLYITREPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 216 AA PAT source 1..216 mol_type protein note Light chain 2 C33F1318 cadena ligera 2 C33F1318 organism synthetic construct constructo sintético NFMLTQPHSVSESPGKTVIISCTRSSGSIASNDVQWYQQRPGSSPTIVIYEDKQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQSYDNNNQVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 358 AA PAT source 1..358 mol_type protein note Heavy chain 1 LAVA177 cadena pesada 1 LAVA177 organism synthetic construct constructo sintético EVQLVESGGGLVQAGGSLRLSCAASGRPFSNYGMGWFRQAPGKKREFVAGISWSGGSTDYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAAVFSGAETAYYPSDDYDYWGQGTQVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLYITREPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLWCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 355 AA PAT source 1..355 mol_type protein note Heavy chain 2 AB266_1_CD33_B12_P09 cadena pesada 2 AB266_1_CD33_B12_P09 organism synthetic construct constructo sintético EVQVVESGGGLVQGGGSLRLSCAASGSIFSINAMGWYHQAPGKQRELVARITGGGATDYVDSVKGRFTISLDSAKSTVYLQMNSLKPEDTAVYHCYADLVTRVGSDLLYDDYWGQGTQVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLYITREPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 17 AA PAT source 1..17 mol_type protein note CDR3 CDR3 organism Llama Llama YADIAANIGSNILYDDY 10 AA PAT source 1..10 mol_type protein note CDR1 CDR1 organism Llama Llama GRPFSNYGMG 10 AA PAT source 1..10 mol_type protein note CDR2 CDR2 organism Llama Llama GISWSGGSTD 17 AA PAT source 1..17 mol_type protein note CDR3 CDR3 organism Llama Llama VFSGAETAYYPSDDYDY 5 AA PAT source 1..5 mol_type protein note CDR1 CDR1 organism Llama Llama NYGMG 17 AA PAT source 1..17 mol_type protein note CDR2 CDR2 organism Llama Llama GISWSGGSTDYADSVKG 7 AA PAT source 1..7 mol_type protein note CDR1 CDR1 organism Llama Llama GRPFSNY 6 AA PAT source 1..6 mol_type protein note CDR2 CDR2 organism Llama Llama SWSGGS 8 AA PAT source 1..8 mol_type protein note CDR1 CDR1 organism Llama Llama GRPFSNYG 8 AA PAT source 1..8 mol_type protein note CDR2 CDR2 organism Llama Llama ISWSGGST 19 AA PAT source 1..19 mol_type protein note CDR3 CDR3 organism Llama Llama AAVFSGAETAYYPSDDYDY 126 AA PAT source 1..126 mol_type protein organism Llama Llama EVQLVESGGGLVQAGGSLRLSCAASGRPFSNYGMGWFRQAPGKKREFVAGISWSGGSTDYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAAVFSGAETAYYPSDDYDYWGQGTQVTVSS 364 AA PAT source 1..364 mol_type protein organism Homo sapiens Homo sapiens MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSEVRTQ 1065 DNA PAT source 1..1065 mol_type other DNA note CD33 heavy chain cadena pesada de CD33 organism synthetic construct constructo sintético caagtgcaacttgtggaaagtggtggcggacttgtgcaagctggtggctcattgaggctgtcttgtgaagcatctggctcaatcttcagcatctttgatatgggttggtatagaagacctcccggggctcagagagaactggtggctagaatcacaaatggtgggattaccaattacctcgattcagttaagggaaggttctctatttccagagacaatgccaagaatactgtgtacttgcaaatgaacagcttgaatgccgaagatacagccgtgtactattgttacgcagatattgcagcaaacattggctcaaacattctgtacgatgactattggggtcaaggaacacaagttacagtcagttctgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtcctgcgccgtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctcgtgagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccggttcacgcagaagtctctctccctgtctccgggaaaa 1074 DNA PAT source 1..1074 mol_type other DNA note Vdelta2 heavy chain cadena pesada de Vdelta2 organism synthetic construct constructo sintético gaagttcagctggttgaaagtggtggtggccttgtgcaagccggtggctcattacgcttgtcatgtgcagcctctggaagacctttcagcaattatgggatggggtggtttagacaagcacccggaaagaaacgcgagtttgttgctggcatttcatggagtggcggaagtacagattatgcagattctgttaaaggacgctttacaattagtcgggacaacgcaaagaataccgtgtatctccagatgaatagccttaagccagaagatacagccgtttattattgtgccgctgttttctctggtgctgaaactgcatactatccatcagacgactacgattattggggtcaaggaactcaagtgacagtttctagtgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagtctctctccctgtctccgggaaaa 358 AA PAT source 1..358 mol_type protein note Heavy chain 1 LAVA177 LAVA177 de cadena pesada 1 organism synthetic construct constructo sintético EVQLVESGGGLVQAGGSLRLSCAASGRPFSNYGMGWFRQAPGKKREFVAGISWSGGSTDYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAAVFSGAETAYYPSDDYDYWGQGTQVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLYITREPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLWCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNRFTQKSLSLSPGK 355 AA PAT source 1..355 mol_type protein note Heavy Chain 2 JL45 JL45 de cadena pesada 2 organism synthetic construct constructo sintético QVQLVESGGGLVQAGGSLRLSCEASGSIFSIFDMGWYRRPPGAQRELVARITNGGITNYLDSVKGRFSISRDNAKNTVYLQMNSLNAEDTAVYYCYADIAANIGSNILYDDYWGQGTQVTVSSEPKSSDKTHTCPPCPAPEAAGGPSVFLFPPKPKDTLYITREPEVTCVVVSVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLSCAVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 117 AA PAT source 1..117 mol_type protein note JL5 VH (C33B1517) JL5 VH (C33B1517) organism synthetic construct constructo sintético QVQLQESGPGLVKPSETLSLTCSVSGASIRNYYWSWIRQTAGKGLEWLGHIYSTGNIHYNPSLKSRVTMSVDTSNNQFSLKLRSVTAADTAVYYCARDNGAALFDYWGQGTLVTVSS 110 AA PAT source 1..110 mol_type protein note JL5 VL (C33B1517) JL5 VL (C33B1517) organism synthetic construct constructo sintético QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNIVNWYQQFPGTAPKLLIYSNNQRPSGVPDRVSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGPVFGPGTKVTVL 369 DNA PAT source 1..369 mol_type other DNA note AB266_1_CD33_B12_P09.VR1 (INS241328) AB266_1_CD33_B12_P09.VR1 (INS241328) organism synthetic construct constructo sintético gaagttcaagttgtcgaatctggcggcgggcttgtgcaaggtggtgggtcattgaggctgtcttgtgctgcatctggttccatcttcagcattaacgccatgggttggtatcatcaagcacccggcaaacagagggaactggtggcaagaattactggaggaggagctaccgattatgtggattccgttaagggtcgcttcacaatcagtctggattcagctaagtctacagtctatctgcaaatgaactcactcaaaccagaagatacagcagtctaccattgttatgcagatcttgtgacaagagtgggatctgatcttctgtacgacgattattggggtcaaggaactcaagttactgtgtcaagt 369 DNA PAT source 1..369 mol_type other DNA note JL45 (INS242239) JL45 (INS242239) organism synthetic construct constructo sintético caagtgcaacttgtggaaagtggtggcggacttgtgcaagctggtggctcattgaggctgtcttgtgaagcatctggctcaatcttcagcatctttgatatgggttggtatagaagacctcccggggctcagagagaactggtggctagaatcacaaatggtgggattaccaattacctcgattcagttaagggaaggttctctatttccagagacaatgccaagaatactgtgtacttgcaaatgaacagcttgaatgccgaagatacagccgtgtactattgttacgcagatattgcagcaaacattggctcaaacattctgtacgatgactattggggtcaaggaacacaagttacagtcagttct 357 DNA PAT source 1..357 mol_type other DNA note C33SB1SC1494 041E121SV7 1.VR1 Heavy (INS159346) C33SB1SC1494 041E121SV7 1.VR1 Pesada (INS159346) organism synthetic construct constructo sintético gaggtgcagctggtggagtctgggggagacgtggtacagcctggggggtccctgagactctcctgtgcagcctctggattcacctttgatgattataccatgcactgggtccgtcaagctccggggaagggtctggagtgggtctctcttgttagttggagtggtggtagcgcatactatgtagactctgtgaagggccgattcaccatctccagagacaacagcaaaaactccctgtatctgcaaatgaacagtctgaaatctgaggacaccgccctgtattactgtgcaaaagaaagtgcatataatgcctactttgactactggggccagggaaccctggtcaccgtctcctca 339 DNA PAT source 1..339 mol_type other DNA note C33SB1SC1494 041E121SV7 1.VR1 Light (INS159345) C33SB1SC1494 041E121SV7 1.VR1 Ligera (INS159345) organism synthetic construct constructo sintético gacatcgtgatgacccagtctccagactccctggctgtgtctctgggcgagagggccaccatctactgcaagtccagccagagtgttttatacagctccaacaataagaactacttagcttggtaccaacagaaggcaggacagcctcctgaactgctcatttactgggcatctacccgggagtccggggtccctgaccgattcagtggcagcgggtctgggacagatttcactctcaccatcagcagcctgcaggctgaggatgtggcactttattactgtcaccaattttatattactccgtacacttttggccaggggaccaaggtggagatcaaa 354 DNA PAT source 1..354 mol_type other DNA note C33F1318 Heavy (INS171943) C33F1318 – Pesada (INS171943) organism synthetic construct constructo sintético gaggtccaacttgtggagtcaggcggcggcctcgtgcaaccagggggtagtttgcgcctgagttgcgctgccagcgggtttactttctcacgatattggatgagttgggttcgacaggcacctgggaagggactcgagtggatggctaatatcaagagggatggatctgaaaaatactatgtcgatgccgtcaggggtcgatttaccatttctcgtgacaatgctaaaaactccctttacctgcaaatgaacagtttgagagctgaagatacagcagtctattattgtgctcgcaatagcggcacttgggaatttgaccaatggggacaaggtacacttgtaacagtctcctca 330 DNA PAT source 1..330 mol_type other DNA note C33F1318 Light (INS171944) C33F1318 Ligera (INS171944) organism synthetic construct constructo sintético aattttatgcttacacagccccattctgtttccgaaagcccaggcaagaccgttatcatctcttgcacccgatcaagcgggtctatagcttccaacgacgtacaatggtaccaacagaggccaggcagcagtcccaccattgtcatttatgaggataaacagcgtccatctggagtacccgaccgttttagtggatctattgattccagctcaaactccgcatctctgactataagtgggctgaagactgaggatgaagccgactactattgtcaatcatacgacaacaacaatcaggtatttggtggcggcaccaagctcaccgtgctt 1074 DNA PAT source 1..1074 mol_type other DNA note GD33B273 Heavy Chain 1 (PBD203084) GD33B273 – cadena pesada 1 (PBD203084) organism synthetic construct constructo sintético gaagttcagctggttgaaagtggtggtggccttgtgcaagccggtggctcattacgcttgtcatgtgcagcctctggaagacctttcagcaattatgggatggggtggtttagacaagcacccggaaagaaacgcgagtttgttgctggcatttcatggagtggcggaagtacagattatgcagattctgttaaaggacgctttacaattagtcgggacaacgcaaagaataccgtgtatctccagatgaatagccttaagccagaagatacagccgtttattattgtgccgctgttttctctggtgctgaaactgcatactatccatcagacgactacgattattggggtcaaggaactcaagtgacagtttctagtgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagtctctctccctgtctccgggaaaa 1065 DNA PAT source 1..1065 mol_type other DNA note GD33B273 Heavy Chain 2 (PBD203084) GD33B273 cadena pesada 2 (PBD203084) organism synthetic construct constructo sintético caagtgcaacttgtggaaagtggtggcggacttgtgcaagctggtggctcattgaggctgtcttgtgaagcatctggctcaatcttcagcatctttgatatgggttggtatagaagacctcccggggctcagagagaactggtggctagaatcacaaatggtgggattaccaattacctcgattcagttaagggaaggttctctatttccagagacaatgccaagaatactgtgtacttgcaaatgaacagcttgaatgccgaagatacagccgtgtactattgttacgcagatattgcagcaaacattggctcaaacattctgtacgatgactattggggtcaaggaacacaagttacagtcagttctgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtcctgcgccgtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctcgtgagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccggttcacgcagaagtctctctccctgtctccgggaaaa 1074 DNA PAT source 1..1074 mol_type other DNA note GD33B112 Heavy Chain 1 (PBD142624) GD33B112 cadena pesada 1 (PBD142624) organism synthetic construct constructo sintético gaagtgcaattagtggaaagtggtggtggtctggtgcaggctggcggaagcctgagactgtcttgtgctgcctctggccggccattttccaactacggcatgggctggttcaggcaggcccctggcaagaaaagagagttcgtggccggcatctcctggtccggcggctctacagattacgccgactccgtgaagggcagattcaccatctctcgggataatgccaagaacaccgtctacctgcagatgaactccctgaagcctgaggacaccgctgtgtactactgcgccgccgtgttcagcggagctgaaaccgcctactatccttccgacgactacgactactggggccagggcacccaagtgaccgtgtcctctgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtcgaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagtctctctccctgtctccgggaaaa 1347 DNA PAT source 1..1347 mol_type other DNA note GD33B112 Heavy Chain 2 (PBD167215) GD33B112 cadena pesada 2 (PBD167215) organism synthetic construct constructo sintético gaagtgcagctggtggagagcggcggggacgtagtgcaacctggcggcagcctgagactgagctgcgccgctagcggcttcaccttcgacgactacaccatgcactgggtgagacaagcccctggcaagggcctggagtgggtgagcctggtgagctggagcggcggcagcgcctactacgtggacagcgtgaagggcagattcaccatcagcagagacaacagcaagaacagcctgtacctgcagatgaacagcctcaagagcgaggacaccgccctgtactactgcgccaaggagagcgcctacaacgcctacttcgactactggggccaaggcaccctggtgaccgtgagcagcgcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacccagacctacatctgcaacgtgaatcacaagcccagcaacaccaaggtggacaagaaagttgagcccaaatcttgtgacaaaactcacacatgtccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtctccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtcctgcgccgtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctcgtgagcaagctcaccgtggacaagtctagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccggttcacgcagaagagcctctccctgtctccgggaaaa 660 DNA PAT source 1..660 mol_type other DNA note GD33B112 Light Chain 2 (PBD167214) GD33B112 cadena ligera 2 (PBD167214) organism synthetic construct constructo sintético gacatcgtgatgacacagagccctgacagcctggccgtgagcctgggcgagagagccaccatctactgcaagagctctcagagcgtgctgtacagcagcaacaacaagaactacctggcctggtatcagcagaaggccggacagcctcctgagctgctgatctactgggctagcacaagagagagcggcgtgcctgacagattcagcggcagcggcagcggcaccgacttcaccctgaccatcagcagcctgcaagccgaggacgtggccctgtactactgccatcagttctacatcaccccttacaccttcggccaaggcaccaaggtggagatcaagcgtacggtggctgcaccatctgtcttcatcttcccgccatctgatgagcagttgaaatctggaactgcctctgttgtgtgcctgctgaataacttctatcccagagaggccaaagtacagtggaaggtggataacgccctccaatcgggtaactcccaggagagtgtcacagagcaggacagcaaggacagcacctacagcctcagcagcaccctgacgctgagcaaagcagactacgagaaacacaaagtctacgcctgcgaagtcacccatcagggcctgagctcgcccgtcacaaagagcttcaacaggggagagtgt 1074 DNA PAT source 1..1074 mol_type other DNA note GD33B116 Heavy Chain 1 (PBD142624) GD33B116 cadena pesada 1 (PBD142624) organism synthetic construct constructo sintético gaagtgcaattagtggaaagtggtggtggtctggtgcaggctggcggaagcctgagactgtcttgtgctgcctctggccggccattttccaactacggcatgggctggttcaggcaggcccctggcaagaaaagagagttcgtggccggcatctcctggtccggcggctctacagattacgccgactccgtgaagggcagattcaccatctctcgggataatgccaagaacaccgtctacctgcagatgaactccctgaagcctgaggacaccgctgtgtactactgcgccgccgtgttcagcggagctgaaaccgcctactatccttccgacgactacgactactggggccagggcacccaagtgaccgtgtcctctgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtcgaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagtctctctccctgtctccgggaaaa 1344 DNA PAT source 1..1344 mol_type other DNA note GD33B116 Heavy Chain 2 (PBD156894) GD33B116 cadena pesada 2 (PBD156894) organism synthetic construct constructo sintético gaggtccaacttgtggagtcaggcggcggcctcgtgcaaccagggggtagtttgcgcctgagttgcgctgccagcgggtttactttctcacgatattggatgagttgggttcgacaggcacctgggaagggactcgagtggatggctaatatcaagagggatggatctgaaaaatactatgtcgatgccgtcaggggtcgatttaccatttctcgtgacaatgctaaaaactccctttacctgcaaatgaacagtttgagagctgaagatacagcagtctattattgtgctcgcaatagcggcacttgggaatttgaccaatggggacaaggtacacttgtaacagtctcctcagcctccaccaagggcccatcggtcttccccctggcaccctcctccaagagcacctctgggggcacagcggccctgggctgcctggtcaaggactacttccccgaaccggtgacggtgtcgtggaactcaggcgccctgaccagcggcgtgcacaccttcccggctgtcctacagtcctcaggactctactccctcagcagcgtggtgaccgtgccctccagcagcttgggcacccagacctacatctgcaacgtgaatcacaagcccagcaacaccaaggtggacaagaaagttgagcccaaatcttgtgacaaaactcacacatgtccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtctccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtcctgcgccgtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctcgtgagcaagctcaccgtggacaagtctagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccggttcacgcagaagagcctctccctgtctccgggaaaa 648 DNA PAT source 1..648 mol_type other DNA note GD33B116 Light Chain 2 (PBD156378) GD33B116 cadena ligera 2 (PBD156378) organism synthetic construct constructo sintético aattttatgcttacacagccccattctgtttccgaaagcccaggcaagaccgttatcatctcttgcacccgatcaagcgggtctatagcttccaacgacgtacaatggtaccaacagaggccaggcagcagtcccaccattgtcatttatgaggataaacagcgtccatctggagtacccgaccgttttagtggatctattgattccagctcaaactccgcatctctgactataagtgggctgaagactgaggatgaagccgactactattgtcaatcatacgacaacaacaatcaggtatttggtggcggcaccaagctcaccgtgcttggtcagcccaaggctgcacccagtgtcactctgttcccgccctcctctgaggagcttcaagccaacaaggccacactggtgtgtctcataagtgacttctacccgggagccgtgacagtggcctggaaggccgatagcagccccgtcaaggcgggagtggagaccaccacaccctccaaacaaagcaacaacaagtacgcggccagcagctatctgagcctgacgcctgagcagtggaagtcccacagaagctacagctgccaggtcacgcatgaagggagcaccgtggagaagacagtggcccctacagaatgttca 1074 DNA PAT source 1..1074 mol_type other DNA note GD33B139 Heavy Chain 1 (PBD171082) GD33B139 cadena pesada 1 (PBD171082) organism synthetic construct constructo sintético gaagtgcaattagtggaaagtggtggtggtctggtgcaggctggcggaagcctgagactgtcttgtgctgcctctggccggccattttccaactacggcatgggctggttcaggcaggcccctggcaagaaaagagagttcgtggccggcatctcctggtccggcggctctacagattacgccgactccgtgaagggcagattcaccatctctcgggataatgccaagaacaccgtctacctgcagatgaactccctgaagcctgaggacaccgctgtgtactactgcgccgccgtgttcagcggagctgaaaccgcctactatccttccgacgactacgactactggggccagggcacccaagtgaccgtgtcctctgagcccaaatctagcgacaaaactcacacatgcccaccgtgcccagcacctgaagccgccgggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtgtcgaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtggtgcctggtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctctacagcaagctcaccgtggacaagagcagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccggttcacgcagaagtctctctccctgtctccgggaaaa 1065 DNA PAT source 1..1065 mol_type other DNA note GD33B139 Heavy Chain 2 (PBD171087) GD33B139 cadena pesada 2 (PBD171087) organism synthetic construct constructo sintético gaagtgcaagtggtggaaagtggtggtggtctcgtgcagggcggcggaagcctgagactgtcttgtgctgcttctggctctatcttctccatcaacgctatgggctggtatcaccaggctcctggcaagcagcgggaactggtggcccggatcaccggcggaggcgctaccgactacgtggactccgtgaagggcagattcaccatctctctggattctgccaagtccacagtgtacctgcagatgaactccctgaaacccgaggacaccgccgtgtaccactgctacgccgatctggtcaccagagtgggctccgacctgctgtacgacgactactggggccaaggcacccaggtgaccgtgtccagcgagcccaaatctagcgacaaaactcacacatgtccaccgtgcccagcacctgaagcagcagggggaccgtcagtcttcctcttccccccaaaacccaaggacaccctctacatcacccgggagcctgaggtcacatgcgtggtggtgagcgtgagccacgaagaccctgaggtcaagttcaactggtacgtggacggcgtggaggtgcataatgccaagacaaagccgcgggaggagcagtacaacagcacgtaccgtgtggtcagcgtcctcaccgtcctgcaccaggactggctgaatggcaaggagtacaagtgcaaggtctccaacaaagccctcccagcccccatcgagaaaaccatctccaaagccaaagggcagccccgagaaccacaggtgtacaccctgcccccatcccgggaggagatgaccaagaaccaggtcagcctgtcctgcgccgtcaaaggcttctatcccagcgacatcgccgtggagtgggagagcaatgggcagccggagaacaactacaagaccacgcctcccgtgctggactccgacggctccttcttcctcgtgagcaagctcaccgtggacaagtctagatggcagcaggggaacgtcttctcatgctccgtgatgcatgaggctctgcacaaccactacacgcagaagagcctctccctgtctccgggtaaa 13 AA PAT source 1..13 mol_type protein note CDR3 CDR3 organism Llama Llama YADIAANIGSNIL